The Three-dimensional Structure of the C-terminal DNA-binding Domain of Human Ku70

Journal of Biological Chemistry

Volumn 276, Issue 41, 2001, Pages 38231-38236

  Zhang, Ziming ^a   Zhu, Lingyang ^a   Lin, Donghai ^a   Chen, Fanqing ^b   Chen, David J ^b   Chen, Yuan ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DNA; HYDROPHOBICITY; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE;

BINDING ACTIVITY;

PROTEINS;

DIMER; DOUBLE STRANDED DNA; HELIX LOOP HELIX PROTEIN; KU ANTIGEN; UNCLASSIFIED DRUG; CELL NUCLEUS ANTIGEN; DNA; DNA BINDING PROTEIN; HELICASE; NUCLEAR PROTEIN; XRCC5 PROTEIN, HUMAN;

ARTICLE; BINDING KINETICS; BINDING SITE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; DNA BINDING; DNA REPAIR; DNA STRAND BREAKAGE; GENE DELETION; HUMAN; HYDROPHOBICITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; NON-PROGRAMMATIC; PROTEIN BINDING; PROTEIN CONFORMATION;

MAMMALIA;

NON-PROGRAMMATIC;

AMINO ACID SEQUENCE; ANTIGENS, NUCLEAR; BINDING SITES; DNA; DNA HELICASES; DNA-BINDING PROTEINS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0035851127     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Critchlow, S. E. & Jackson, S. P. (1998) Trends Biochem. Sci. 23, 394-398
2. Blier, P. R., Griffith, A. J., Craft, J. & Hardin, J. A. (1993) J. Biol. Chem. 268, 7594-7601
3. Cary, R. B., Peterson, S. R., Wang, J., Bear, D. G., Bradbury, E. M. & Chen, D. J. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 4267-4272
4. Hammarsten, O. & Chu, G. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 525-530
5. Critchlow, S. E., Bowater, R. P. & Jackson, S. P. (1997) Curr. Biol. 7, 588-598
6. Leber, R., Wise, T. W., Mizuta, R. & Meek, K. (1998) J. Biol. Chem. 273, 1794-1801
7. Koonin, E. V., Altschul, S. F. & Bork, P. (1996) Nat. Genet. 13, 266-268
8. Grawunder, U., Wilm, M., Wu, X., Kulesza, P., Wilson, T. E., Mann, M. & Lieber, M. R. (1997) Nature 388, 492-495
9. Ramsden, D. A. & Gellert, M. (1998) EMBO J. 17, 609-614
10. Chou, C. H., Wang, J., Knuth, M. W. & Reeves, W. H. (1992) J. Exp. Med. 175, 1677-1684
11. Wu, X. & Lieber, M. R. (1996) Mol. Cell. Biol. 16, 5186-5193
12. Wang, J., Dong, X. & Reeves, W. H. (1998) J. Biol. Chem. 273, 31068-31074
13. Wang, J., Dong, X., Myung, K., Hendrickson, E. A. & Reeves, W. H. (1998) J. Biol. Chem. 273, 842-848
14. Bax, A., Vuister, G. W., Grzesiek, S., Delaglio, F., Wang, A. C., Tschudin, R. & Zhu, G. (1994) Methods Enzymol. 239, 79-105
15. Clore, G. M. & Gronenborn, A. M. (1994) Methods Enzymol. 239, 349-362
16. Clore G. M., Bax, A. & Gronenborn A. M. (1991) J. Biomol. NMR 1, 13-22
17. Archer, S. J., Ikura, M. & Torchia, D. (1991) J. Magn. Reson. 95, 636-641
18. Kuboniwa, H., Grzesiek, S., Delaglio, F. & Bax, A. (1994) J. Biomol. NMR 4, 871-878
19. Guntert, P., Mumenthaler, C. & Wuthrich, K. (1997) J. Mol. Biol. 273, 283-298
20. Raaijmakers, H., Vix, O., Toro, I., Golz, S., Kemper, B. & Suck, D. (1999) EMBO J. 18, 1447-1458
21. Koike, M., Ikuta, T., Miyasaka, T. & Shiomi, T. (1999) Exp. Cell. Res. 250, 401-413
22. Rost, B. (1998) Methods Enzymol. 266, 525-539
23. Reeves, W. H., Pierani, A., Chou, C., Ng, T., Nicastri, C., Roeder, R. G. & Sthoeger, Z. M. (1991) J. Immunol. 146, 2678-2686
24. Hore, P. J. (1983) J. Magn. Reson. 55, 283-300
25. Ikura, M. & Bax, A. (1992) J. Am. Chem. Soc. 114, 2433-2440
26. Chen, Y., Reizer, J., Saier, M. H., Jr., Fairbrother, W. J. & Wright, P. E. (1993) Biochemistry 32, 32-37
27. Yoo, S., Kimzey, A. & Dynan, W. S. (1999) J. Biol. Chem. 274, 20034-20039
28. Holmes, L. & Sander, C. (1993) J. Mol. Biol. 233, 123-138
29. Laskowski, R. A., Rullmann, J. A. C., MacArthur, M. W., Kaptein, R. & Thornton, J. (1996) J. Biomol. NMR 8, 477-486
30. Allison, T. J., Wood, T. C., Briercheck, D. M., Rastinejad, F., Richardson, J. P. & Rule, G. S. (1998) Nat. Struct. Biol. 5, 352-356
31. Briercheck, D. M., Wood, T. C., Allison, T. J., Richardson, J. P. & Rule, G. S. (1998) Nat. Struct. Biol. 5, 393-398
32. Onesti, S., Miller, A. D. & Brick, P. (1995) Structure 3, 163-176
33. Golz, S., Christoph, A., Birkenkamp-Detroder, K. & Kemper, B. (1997) Eur. J. Biochem. 245, 573-580
34. Birkenbihl, R. P. & Kemper, B. (1998) EMBO J. 17, 4527-4534
35. Cavarelli, J., Rees, B., Ruff, M., Thierry, J. C. & Moras, D. (1993) Nature 362, 181-184
36. Brunger, A. T., Adams, P. O., Clore, G. M., Delano, W. L., Gros, P., Grosse-Kunsleve, R. W., Jiang, J.-S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. F., Rice, L. M., Simonson, T., and Warren, G. L. (1998) D54, 905-921