-
1
-
-
0037429820
-
Long-suffering lipids gain respect
-
Wilson, J. F. Long-suffering lipids gain respect. The Scientist 17, 34-46 (2003).
-
(2003)
The Scientist
, vol.17
, pp. 34-46
-
-
Wilson, J.F.1
-
2
-
-
0344413852
-
Lipidomics is emerging
-
Lagarde, M., Geloen, A., Record, M., Vance, D. & Spener, F. Lipidomics is emerging. Biochim. Biophys. Acta 1634, 61 (2003).
-
(2003)
Biochim. Biophys. Acta
, vol.1634
, pp. 61
-
-
Lagarde, M.1
Geloen, A.2
Record, M.3
Vance, D.4
Spener, F.5
-
4
-
-
0032803887
-
Protein lipid interactions on the surfaces of cell membranes
-
Glomset, J. A. Protein lipid interactions on the surfaces of cell membranes. Curr. Opin. Struct. Biol. 9, 425-427 (1999).
-
(1999)
Curr. Opin. Struct. Biol.
, vol.9
, pp. 425-427
-
-
Glomset, J.A.1
-
5
-
-
0028358009
-
Structure catalytic mechanism of secretory phospholipases A2
-
Scott, D. L. & Sigler, P. B. Structure and catalytic mechanism of secretory phospholipases A2. Adv. Protein Chem. 45, 53-88 (1994).
-
(1994)
Adv. Protein Chem.
, vol.45
, pp. 53-88
-
-
Scott, D.L.1
Sigler, P.B.2
-
6
-
-
0034739443
-
Do membrane-bound enzymes access their substrates from the membrane or aqueous phase: Interfacial versus non-interfacial enzymes
-
Gelb, M. H., Min, J. H. & Jain, M. K. Do membrane-bound enzymes access their substrates from the membrane or aqueous phase: interfacial versus non-interfacial enzymes. Biochim. Biophys. Acta 1488, 20-27 (2000).
-
(2000)
Biochim. Biophys. Acta
, vol.1488
, pp. 20-27
-
-
Gelb, M.H.1
Min, J.H.2
Jain, M.K.3
-
7
-
-
0032544230
-
Structure of type IIbeta phosphatidylinositol phosphate kinase: A protein kinase fold flattened for interfacial phosphorylation
-
Rao, V. D., Misra, S., Boronenkov, I. V., Anderson, R. A. & Hurley, J. H. Structure of type IIbeta phosphatidylinositol phosphate kinase: a protein kinase fold flattened for interfacial phosphorylation. Cell 94, 829-839 (1998).
-
(1998)
Cell
, vol.94
, pp. 829-839
-
-
Rao, V.D.1
Misra, S.2
Boronenkov, I.V.3
Anderson, R.A.4
Hurley, J.H.5
-
8
-
-
0035805064
-
Specificity determinants in phosphoinositide dephosphorylation: Crystal structure of an archetypal inositol polyphosphate 5-phosphatase
-
Tsujishita, Y., Guo, S., Stolz, L. E., York, J. D. & Hurley, J. H. Specificity determinants in phosphoinositide dephosphorylation: crystal structure of an archetypal inositol polyphosphate 5-phosphatase. Cell 105, 379-389 (2001).
-
(2001)
Cell
, vol.105
, pp. 379-389
-
-
Tsujishita, Y.1
Guo, S.2
Stolz, L.E.3
York, J.D.4
Hurley, J.H.5
-
9
-
-
0029835971
-
Phospholipases: Structural functional motifs for working at an interface
-
Roberts, M. F. Phospholipases: structural and functional motifs for working at an interface. FASEB J. 10, 1159-1172 (1996).
-
(1996)
FASEB J.
, vol.10
, pp. 1159-1172
-
-
Roberts, M.F.1
-
10
-
-
0033969444
-
The activation loop of phosphatidylinositol phosphate kinases determines signaling specificity
-
Kunz, J. et al. The activation loop of phosphatidylinositol phosphate kinases determines signaling specificity. Mol. Cells 5, 1-11 (2000).
-
(2000)
Mol. Cells
, vol.5
, pp. 1-11
-
-
Kunz, J.1
-
11
-
-
32644465780
-
-
(eds Muller G. Petry S.) (Wiley-VCH Weinheim Germany)
-
Goni, F. M. & Alonso, A. in Lipases and Phospholipases in Drug Development (eds Muller, G. & Petry, S.) 79-100 (Wiley-VCH, Weinheim, Germany, 2004).
-
(2004)
Lipases Phospholipases in Drug Development
, pp. 79-100
-
-
Goni, F.M.1
Alonso, A.2
-
12
-
-
0017750496
-
Refinement of the fluid-mosaic model of membrane structure
-
Israelachvili, J. N. Refinement of the fluid-mosaic model of membrane structure. Biochim. Biophys. Acta 469, 221-225 (1977).
-
(1977)
Biochim. Biophys. Acta
, vol.469
, pp. 221-225
-
-
Israelachvili, J.N.1
-
13
-
-
0021878252
-
Proton-induced fusion of oleic acid-phosphatidylethanolamine liposomes
-
Duzgunes, N., Straubinger, R. M., Baldwin, P. A., Friend, D. S. & Papahadjopoulos, D. Proton-induced fusion of oleic acid-phosphatidylethanolamine liposomes. Biochemistry 24, 3091-3098 (1985).
-
(1985)
Biochemistry
, vol.24
, pp. 3091-3098
-
-
Duzgunes, N.1
Straubinger, R.M.2
Baldwin, P.A.3
Friend, D.S.4
Papahadjopoulos, D.5
-
14
-
-
0029147925
-
Lipids in biological membrane fusion
-
Chernomordik, L., Kozlov, M. M. & Zimmerberg, J. Lipids in biological membrane fusion. J. Membr. Biol. 146, 1-14 (1995).
-
(1995)
J. Membr. Biol.
, vol.146
, pp. 1-14
-
-
Chernomordik, L.1
Kozlov, M.M.2
Zimmerberg, J.3
-
15
-
-
0035016931
-
Ternary phase diagram of dipalmitoyl-PC/dilauroyl-PC/cholesterol: Nanoscopic domain formation driven by cholesterol
-
Feigenson, G. W. & Buboltz, J. T. Ternary phase diagram of dipalmitoyl-PC/dilauroyl-PC/cholesterol: nanoscopic domain formation driven by cholesterol. Biophys. J. 80, 2775-2788 (2001).
-
(2001)
Biophys. J.
, vol.80
, pp. 2775-2788
-
-
Feigenson, G.W.1
Buboltz, J.T.2
-
16
-
-
0027397544
-
Inositol trisphosphate calcium signaling
-
Berridge, M. J. Inositol trisphosphate and calcium signaling. Nature 361, 315-325 (1993).
-
(1993)
Nature
, vol.361
, pp. 315-325
-
-
Berridge, M.J.1
-
17
-
-
0028216874
-
The protein kinase C family for neuronal signaling
-
Tanaka, C. & Nishizuka, Y. The protein kinase C family for neuronal signaling. Annu. Rev. Neurosci. 17, 551-567 (1994).
-
(1994)
Annu. Rev. Neurosci.
, vol.17
, pp. 551-567
-
-
Tanaka, C.1
Nishizuka, Y.2
-
18
-
-
2942716956
-
Diacylglycerol kinases
-
Luo, B., Regier, D. S., Prescott, S. M. & Topham, M. K. Diacylglycerol kinases. Cell Signal. 16, 983-989 (2004).
-
(2004)
Cell Signal.
, vol.16
, pp. 983-989
-
-
Luo, B.1
Regier, D.S.2
Prescott, S.M.3
Topham, M.K.4
-
19
-
-
0033571069
-
Phosphatidic acid a key intermediate in lipid metabolism
-
Athenstaedt, K. & Daum, G. Phosphatidic acid, a key intermediate in lipid metabolism. Eur. J. Biochem. 266, 1-16 (1999).
-
(1999)
Eur. J. Biochem.
, vol.266
, pp. 1-16
-
-
Athenstaedt, K.1
Daum, G.2
-
20
-
-
0942290439
-
How versatile are inositol phosphate kinases?
-
Shears, S. B. How versatile are inositol phosphate kinases? Biochem. J. 377, 265-280 (2004).
-
(2004)
Biochem. J.
, vol.377
, pp. 265-280
-
-
Shears, S.B.1
-
21
-
-
2942609102
-
Eicosanomics: Targeted lipidomics of eicosanoids in biological systems
-
Balazy, M. Eicosanomics: targeted lipidomics of eicosanoids in biological systems. Prostaglandins Other Lipid Mediat. 73, 173-180 (2004).
-
(2004)
Prostaglandins Other Lipid Mediat.
, vol.73
, pp. 173-180
-
-
Balazy, M.1
-
22
-
-
7444230581
-
Sphingomyelin cholesterol: From membrane biophysics rafts to potential medical applications
-
Barenholz, Y. Sphingomyelin and cholesterol: from membrane biophysics and rafts to potential medical applications. Subcell. Biochem. 37, 167-215 (2004).
-
(2004)
Subcell. Biochem.
, vol.37
, pp. 167-215
-
-
Barenholz, Y.1
-
23
-
-
2942754160
-
Sphingolipids in inflammation: Roles implications
-
Pettus, B. J., Chalfant, C. E. & Hannun, Y. A. Sphingolipids in inflammation: roles and implications. Curr. Mol. Med. 4, 405-418 (2004).
-
(2004)
Curr. Mol. Med.
, vol.4
, pp. 405-418
-
-
Pettus, B.J.1
Chalfant, C.E.2
Hannun, Y.A.3
-
24
-
-
1542358155
-
Ceramide synthesis metabolism as a target for cancer therapy
-
Reynolds, C. P., Maurer, B. J. & Kolesnick, R. N. Ceramide synthesis and metabolism as a target for cancer therapy. Cancer Lett. 206, 160-180 (2004).
-
(2004)
Cancer Lett.
, vol.206
, pp. 160-180
-
-
Reynolds, C.P.1
Maurer, B.J.2
Kolesnick, R.N.3
-
25
-
-
3242696730
-
Physiological pathological actions of sphingosine 1-phosphate
-
Hla, T. Physiological and pathological actions of sphingosine 1-phosphate. Semin. Cell Dev. Biol. 15, 513-520 (2004).
-
(2004)
Semin. Cell Dev. Biol.
, vol.15
, pp. 513-520
-
-
Hla, T.1
-
26
-
-
15244341285
-
Sphingosine kinase signalling in immune cells
-
Kee, T. H., Vit, P. & Melendez, A. J. Sphingosine kinase signalling in immune cells. Clin. Exp. Pharmacol. Physiol. 32, 153-161 (2005).
-
(2005)
Clin. Exp. Pharmacol. Physiol.
, vol.32
, pp. 153-161
-
-
Kee, T.H.1
Vit, P.2
Melendez, A.J.3
-
27
-
-
0035980759
-
Phosphoinositides key molecules for regulation of actin cytoskeletal organization membrane traffic from the plasma membrane
-
Takenawa, T. & Itoh, T. Phosphoinositides, key molecules for regulation of actin cytoskeletal organization and membrane traffic from the plasma membrane. Biochim. Biophys. Acta 1533, 190-206 (2001).
-
(2001)
Biochim. Biophys. Acta
, vol.1533
, pp. 190-206
-
-
Takenawa, T.1
Itoh, T.2
-
28
-
-
2942623783
-
Inaugural article: Protein-lipid interactions phosphoinositide metabolism in membrane traffic: Insights from vesicle recycling in nerve terminals
-
Wenk, M. R. & De Camilli, P. Inaugural article: Protein-lipid interactions and phosphoinositide metabolism in membrane traffic: Insights from vesicle recycling in nerve terminals. Proc. Natl Acad. Sci. USA 101, 8262-8269 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 8262-8269
-
-
Wenk, M.R.1
De Camilli, P.2
-
29
-
-
0035313710
-
Subcellular targeting by membrane lipids
-
Hurley, J. H. & Meyer, T. Subcellular targeting by membrane lipids. Curr. Opin. Cell Biol. 13, 146-152 (2001).
-
(2001)
Curr. Opin. Cell Biol.
, vol.13
, pp. 146-152
-
-
Hurley, J.H.1
Meyer, T.2
-
30
-
-
0037177352
-
Visualizing cellular phosphoinositide pools with GFP-fused protein- modules
-
Balla, T. & Varnai, P. Visualizing cellular phosphoinositide pools with GFP-fused protein- modules. Sci STKE L3 (2002).
-
(2002)
Sci STKE
-
-
Balla, T.1
Varnai, P.2
-
31
-
-
14544307864
-
Phospholipase Cγ1 controls surface expression of TRPC3 through an intermolecular PH domain
-
van Rossum, D. B. et al. Phospholipase Cγ1 controls surface expression of TRPC3 through an intermolecular PH domain. Nature 434, 99-104 (2005).
-
(2005)
Nature
, vol.434
, pp. 99-104
-
-
van Rossum, D.B.1
-
32
-
-
2342556630
-
FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P
-
Godi, A. et al. FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P. Nature Cell Biol. 6, 393-404 (2004).
-
(2004)
Nature Cell Biol.
, vol.6
, pp. 393-404
-
-
Godi, A.1
-
33
-
-
0035424239
-
The role of phosphoinositides in membrane transport
-
Simonsen, A., Wurmser, A. E., Emr, S. D. & Stenmark, H. The role of phosphoinositides in membrane transport. Curr. Opin. Cell Biol. 13, 485-492 (2001).
-
(2001)
Curr. Opin. Cell Biol.
, vol.13
, pp. 485-492
-
-
Simonsen, A.1
Wurmser, A.E.2
Emr, S.D.3
Stenmark, H.4
-
34
-
-
0346729925
-
Vacuole size control: Regulation of PtdIns(3 5)P2 levels by the vacuole-associated Vac14-Fig4 complex a PtdIns(3 5)P2-specific phosphatase
-
Rudge, S. A., Anderson, D. M. & Emr, S. D. Vacuole size control: regulation of PtdIns(3, 5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3, 5)P2-specific phosphatase. Mol. Biol. Cell 15, 24-36 (2004).
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 24-36
-
-
Rudge, S.A.1
Anderson, D.M.2
Emr, S.D.3
-
35
-
-
1642523683
-
Lipopenia and skin barrier abnormalities in DGAT2-deficient mice
-
Stone, S. J. et al. Lipopenia and skin barrier abnormalities in DGAT2-deficient mice. J. Biol. Chem. 279, 11767-11776 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 11767-11776
-
-
Stone, S.J.1
-
36
-
-
4344598315
-
Lipid metabolic enzymes: Emerging drug targets for the treatment of obesity
-
Shi, Y. & Burn, P. Lipid metabolic enzymes: emerging drug targets for the treatment of obesity. Nature Rev. Drug Discov. 3, 695-710 (2004).
-
(2004)
Nature Rev. Drug Discov.
, vol.3
, pp. 695-710
-
-
Shi, Y.1
Burn, P.2
-
38
-
-
0037484189
-
Orlistat in the treatment of obesity
-
Hollander, P. Orlistat in the treatment of obesity. Prim. Care 30, 427-440 (2003).
-
(2003)
Prim. Care
, vol.30
, pp. 427-440
-
-
Hollander, P.1
-
39
-
-
0035804251
-
The lipid phosphatase SHIP2 controls insulin sensitivity
-
Clement, S. et al. The lipid phosphatase SHIP2 controls insulin sensitivity. Nature 409, 92-97 (2001).
-
(2001)
Nature
, vol.409
, pp. 92-97
-
-
Clement, S.1
-
40
-
-
20044364159
-
Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity
-
Sleeman, M. W. et al. Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity. Nature Med. 11, 199-205 (2005).
-
(2005)
Nature Med.
, vol.11
, pp. 199-205
-
-
Sleeman, M.W.1
-
41
-
-
0037067570
-
Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss
-
Cohen, P. et al. Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss. Science 297, 240-243 (2002).
-
(2002)
Science
, vol.297
, pp. 240-243
-
-
Cohen, P.1
-
42
-
-
0035787305
-
Intracellular organization of insulin signaling GLUT4 translocation
-
Watson, R. T. & Pessin, J. E. Intracellular organization of insulin signaling and GLUT4 translocation. Recent Prog. Horm. Res. 56, 175-193 (2001).
-
(2001)
Recent Prog. Horm. Res.
, vol.56
, pp. 175-193
-
-
Watson, R.T.1
Pessin, J.E.2
-
43
-
-
0029948212
-
Mechanism of free fatty acid-induced insulin resistance in humans
-
Roden, M. et al. Mechanism of free fatty acid-induced insulin resistance in humans. J. Clin. Invest 97, 2859-2865 (1996).
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 2859-2865
-
-
Roden, M.1
-
44
-
-
1542713799
-
Joe Goldstein Mike Brown: From cholesterol homeostasis to new paradigms in membrane biology
-
Anderson, R. G. Joe Goldstein and Mike Brown: from cholesterol homeostasis to new paradigms in membrane biology. Trends Cell Biol. 13, 534-539 (2003).
-
(2003)
Trends Cell Biol.
, vol.13
, pp. 534-539
-
-
Anderson, R.G.1
-
45
-
-
0043172415
-
The SREBP pathway - Insights from Insigs and insects
-
Rawson, R. B. The SREBP pathway - insights from Insigs and insects. Nature Rev. Mol. Cell Biol. 4, 631-640 (2003).
-
(2003)
Nature Rev. Mol. Cell Biol.
, vol.4
, pp. 631-640
-
-
Rawson, B.1
-
46
-
-
0036846241
-
Lipid metabolome-wide effects of the PPARgamma agonist rosiglitazone
-
Watkins, S. M., Reifsnyder, P. R., Pan, H. J., German, J. B. & Leiter, E. H. Lipid metabolome-wide effects of the PPARgamma agonist rosiglitazone. J. Lipid Res. 43, 1809-1817 (2002).
-
(2002)
J. Lipid Res.
, vol.43
, pp. 1809-1817
-
-
Watkins, S.M.1
Reifsnyder, P.R.2
Pan, H.J.3
German, J.B.4
Leiter, E.H.5
-
47
-
-
0035874921
-
G-protein signaling through tubby proteins
-
Santagata, S. et al. G-protein signaling through tubby proteins. Science 292, 2041-2050 (2001).
-
(2001)
Science
, vol.292
, pp. 2041-2050
-
-
Santagata, S.1
-
48
-
-
0347132262
-
Tubby proteins: The plot thickens
-
Carroll, K., Gomez, C. & Shapiro, L. Tubby proteins: the plot thickens. Nature Rev. Mol. Cell Biol. 5, 55-63 (2004).
-
(2004)
Nature Rev. Mol. Cell Biol.
, vol.5
, pp. 55-63
-
-
Carroll, K.1
Gomez, C.2
Shapiro, L.3
-
49
-
-
0024601010
-
PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells
-
Auger, K. R., Serunian, L. A., Soltoff, S. P., Libby, P. & Cantley, L. C. PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells. Cell 57, 167-175 (1989).
-
(1989)
Cell
, vol.57
, pp. 167-175
-
-
Auger, K.R.1
Serunian, L.A.2
Soltoff, S.P.3
Libby, P.4
Cantley, L.C.5
-
50
-
-
0038650888
-
Dynamics of phosphoinositides in membrane retrieval insertion
-
Czech, M. P. Dynamics of phosphoinositides in membrane retrieval and insertion. Annu. Rev. Physiol. 65, 791-815 (2003).
-
(2003)
Annu. Rev. Physiol.
, vol.65
, pp. 791-815
-
-
Czech, M.P.1
-
51
-
-
0032577699
-
The tumor suppressor PTEN/MMAC1 delphosphorylates the lipid second messenger phosphatidylinositol 3 4 5-trisphosphate
-
Maehama, T. & Dixon, J. E. The tumor suppressor, PTEN/MMAC1, delphosphorylates the lipid second messenger, phosphatidylinositol 3, 4, 5-trisphosphate. J. Biol. Chem. 273, 13375-13378 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
52
-
-
0038538512
-
Phosphoinositide signaling disorders in human diseases
-
Pendaries, C., Tronchere, H., Plantavid, M. & Payrastre, B. Phosphoinositide signaling disorders in human diseases. FEBS Lett. 546, 25-31 (2003).
-
(2003)
FEBS Lett.
, vol.546
, pp. 25-31
-
-
Pendaries, C.1
Tronchere, H.2
Plantavid, M.3
Payrastre, B.4
-
53
-
-
3142749712
-
Long-lived Drosophila with overexpressed dFOXO in adult fat body
-
Giannakou, M. E. et al. Long-lived Drosophila with overexpressed dFOXO in adult fat body. Science 305, 361 (2004).
-
(2004)
Science
, vol.305
, pp. 361
-
-
Giannakou, M.E.1
-
54
-
-
2342460325
-
PI 3-kinase inhibition: A therapeutic target for respiratory disease
-
Finan, P. M. & Thomas, M. J. PI 3-kinase inhibition: a therapeutic target for respiratory disease. Biochem. Soc. Trans. 32, 378-382 (2004).
-
(2004)
Biochem. Soc. Trans.
, vol.32
, pp. 378-382
-
-
Finan, P.M.1
Thomas, M.J.2
-
55
-
-
2342472012
-
Towards an understanding of isoform specificity in phosphoinositide 3-kinase signalling in lymphocytes
-
Fruman, D. A. Towards an understanding of isoform specificity in phosphoinositide 3-kinase signalling in lymphocytes. Biochem. Soc. Trans. 32, 315-319 (2004).
-
(2004)
Biochem. Soc. Trans.
, vol.32
, pp. 315-319
-
-
Fruman, D.A.1
-
56
-
-
2342472006
-
Phosphatases as small-molecule targets: Inhibiting the endogenous inhibitors of kinases
-
Schmid, A. C. & Woscholski, R. Phosphatases as small-molecule targets: inhibiting the endogenous inhibitors of kinases. Biochem. Soc. Trans. 32, 348-349 (2004).
-
(2004)
Biochem. Soc. Trans.
, vol.32
, pp. 348-349
-
-
Schmid, A.C.1
Woscholski, R.2
-
57
-
-
2442596885
-
Phosphoinositide 3-kinases as targets for therapeutic intervention
-
Wetzker, R. & Rommel, C. Phosphoinositide 3-kinases as targets for therapeutic intervention. Curr. Pharm. Des 10, 1915-1922 (2004).
-
(2004)
Curr. Pharm. Des.
, vol.10
, pp. 1915-1922
-
-
Wetzker, R.1
Rommel, C.2
-
58
-
-
2442661614
-
Cathepsin D links TNF-induced acid sphingomyelinase to Bid-mediated caspase-9 and-3 activation
-
Heinrich, M. et al. Cathepsin D links TNF-induced acid sphingomyelinase to Bid-mediated caspase-9 and-3 activation. Cell Death. Differ. 11, 550-563 (2004).
-
(2004)
Cell Death Differ.
, vol.11
, pp. 550-563
-
-
Heinrich, M.1
-
59
-
-
0029148660
-
Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals
-
Bose, R. et al. Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals. Cell 82, 405-414 (1995).
-
(1995)
Cell
, vol.82
, pp. 405-414
-
-
Bose, R.1
-
60
-
-
3543114272
-
Biologically active sphingolipids in cancer pathogenesis treatment
-
Ogretmen, B. & Hannun, Y. A. Biologically active sphingolipids in cancer pathogenesis and treatment. Nature Rev. Cancer 4, 604-616 (2004).
-
(2004)
Nature Rev. Cancer
, vol.4
, pp. 604-616
-
-
Ogretmen, B.1
Hannun, Y.A.2
-
61
-
-
0034735916
-
An oncogenic role of sphingosine kinase
-
Xia, P. et al. An oncogenic role of sphingosine kinase. Curr. Biol. 10, 1527-1530 (2000).
-
(2000)
Curr. Biol.
, vol.10
, pp. 1527-1530
-
-
Xia, P.1
-
62
-
-
0034974903
-
Differential regulation of sphingosine-1-phosphate- VEGF-induced endothelial cell chemotaxis. Involvement of G(ialpha2)-linked Rho kinase activity
-
Liu, F. et al. Differential regulation of sphingosine-1-phosphate- and VEGF-induced endothelial cell chemotaxis. Involvement of G(ialpha2)-linked Rho kinase activity. Am. J. Respir. Cell Mol. Biol. 24, 711-719 (2001).
-
(2001)
Am. J. Respir. Cell Mol. Biol.
, vol.24
, pp. 711-719
-
-
Liu, F.1
-
63
-
-
0037162092
-
Biological activities metabolism of the lysophosphoinositides glycerophosphoinositols
-
Corda, D., Iurisci, C. & Berrie, C. P. Biological activities and metabolism of the lysophosphoinositides and glycerophosphoinositols. Biochim. Biophys. Acta 1582, 52-69 (2002).
-
(2002)
Biochim. Biophys. Acta
, vol.1582
, pp. 52-69
-
-
Corda, D.1
Iurisci, C.2
Berrie, C.P.3
-
64
-
-
10744221197
-
Antitumor activity of lysophosphatidic acid acyltransferase-beta inhibitors a novel class of agents in multiple myeloma
-
Hideshima, T. et al. Antitumor activity of lysophosphatidic acid acyltransferase-beta inhibitors, a novel class of agents, in multiple myeloma. Cancer Res. 63, 8428-8436 (2003).
-
(2003)
Cancer Res.
, vol.63
, pp. 8428-8436
-
-
Hideshima, T.1
-
65
-
-
0345868348
-
Nonsteroidal anti-inflammatory drugs cyclooxygenase-2 selective inhibitors for prostate cancer chemoprevention
-
Basler, J. W. & Piazza, G. A. Nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 selective inhibitors for prostate cancer chemoprevention. J. Urol. 171, S59-S62 (2004).
-
(2004)
J. Urol.
, vol.171
-
-
Basler, J.W.1
Piazza, G.A.2
-
66
-
-
0035074215
-
Phosphoinositides in membrane traffic at the synapse
-
Cremona, O. & De Camilli, P. Phosphoinositides in membrane traffic at the synapse. J. Cell. Sci. 114, 1041-1052 (2001).
-
(2001)
J. Cell. Sci.
, vol.114
, pp. 1041-1052
-
-
Cremona, O.1
De Camilli, P.2
-
67
-
-
1242338183
-
Involvement of oxidative stress-induced abnormalities in ceramide cholesterol metabolism in brain aging Alzheimer's disease
-
Cutler, R. G. et al. Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease. Proc. Natl Acad. Sci. USA 101, 2070-2075 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 2070-2075
-
-
Cutler, R.G.1
-
68
-
-
0028885854
-
GM1 ganglioside-bound amyloid beta-protein (A beta): A possible form of preamyloid in Alzheimer's disease
-
Yanagisawa, K., Odaka, A., Suzuki, N. & Ihara, Y. GM1 ganglioside-bound amyloid beta-protein (A beta): a possible form of preamyloid in Alzheimer's disease. Nature Med. 1, 1062-1066 (1995).
-
(1995)
Nature Med.
, vol.1
, pp. 1062-1066
-
-
Yanagisawa, K.1
Odaka, A.2
Suzuki, N.3
Ihara, Y.4
-
69
-
-
0035834655
-
Exposure to long chain polyunsaturated fatty acids triggers rapid multimerization of synucleins
-
Perrin, R. J., Woods, W. S., Clayton, D. F. & George, J. M. Exposure to long chain polyunsaturated fatty acids triggers rapid multimerization of synucleins. J. Biol. Chem. 276, 41958-41962 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 41958-41962
-
-
Perrin, R.J.1
Woods, W.S.2
Clayton, D.F.3
George, J.M.4
-
70
-
-
0037456578
-
The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease
-
Sharon, R. et al. The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease. Neuron 37, 583-595 (2003).
-
(2003)
Neuron
, vol.37
, pp. 583-595
-
-
Sharon, R.1
-
71
-
-
0346059412
-
Glucocerebrosidase mutations in subjects with parkinsonism
-
Lwin, A., Orvisky, E., Goker-Alpan, O., LaMarca, M. E. & Sidransky, E. Glucocerebrosidase mutations in subjects with parkinsonism. Mol. Genet. Metab 81, 70-73 (2004).
-
(2004)
Mol. Genet. Metab.
, vol.81
, pp. 70-73
-
-
Lwin, A.1
Orvisky, E.2
Goker-Alpan, O.3
LaMarca, M.E.4
Sidransky, E.5
-
72
-
-
0000721551
-
A defect in cholesterol esterification in Niemann-Pick disease (type C) patients
-
Pentchev, P. G. et al. A defect in cholesterol esterification in Niemann-Pick disease (type C) patients. Proc. Natl Acad. Sci. USA 82, 8247-8251 (1985).
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 8247-8251
-
-
Pentchev, P.G.1
-
73
-
-
4744363991
-
The pathophysiology mechanisms of NP-C disease
-
Sturley, S. L., Patterson, M. C., Balch, W. & Liscum, L. The pathophysiology and mechanisms of NP-C disease. Biochim. Biophys. Acta 1685, 83-87 (2004).
-
(2004)
Biochim. Biophys. Acta
, vol.1685
, pp. 83-87
-
-
Sturley, S.L.1
Patterson, M.C.2
Balch, W.3
Liscum, L.4
-
74
-
-
7944233158
-
Cell biology of protein misfolding: The examples of Alzheimer's Parkinson's diseases
-
Selkoe, D. J. Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases. Nature Cell Biol. 6, 1054-1061 (2004).
-
(2004)
Nature Cell Biol.
, vol.6
, pp. 1054-1061
-
-
Selkoe, D.J.1
-
75
-
-
0035899360
-
Structural mimicry in bacterial virulence
-
Stebbins, C. E. & Galan, J. E. Structural mimicry in bacterial virulence. Nature 412, 701-705 (2001).
-
(2001)
Nature
, vol.412
, pp. 701-705
-
-
Stebbins, C.E.1
Galan, J.E.2
-
76
-
-
2942718724
-
Protein kinase G from pathogenic mycobacteria promotes survival within macrophages
-
Walburger, A. et al. Protein kinase G from pathogenic mycobacteria promotes survival within macrophages. Science 304, 1800-1804 (2004).
-
(2004)
Science
, vol.304
, pp. 1800-1804
-
-
Walburger, A.1
-
77
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak, A. et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282, 2085-2088 (1998).
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
-
78
-
-
3142724031
-
Toll-like receptor signalling
-
Akira, S. & Takeda, K. Toll-like receptor signalling. Nature Rev. Immunol. 4, 499-511 (2004).
-
(2004)
Nature Rev. Immunol.
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
79
-
-
0037459076
-
Membrane fusion
-
Jahn, R., Lang, T. & Sudhof, T. C. Membrane fusion. Cell 112, 519-533 (2003).
-
(2003)
Cell
, vol.112
, pp. 519-533
-
-
Jahn, R.1
Lang, T.2
Sudhof, T.C.3
-
80
-
-
0030949124
-
Functional rafts in cell membranes
-
Simons, K. & Ikonen, E. Functional rafts in cell membranes. Nature 387, 569-572 (1997).
-
(1997)
Nature
, vol.387
, pp. 569-572
-
-
Simons, K.1
Ikonen, E.2
-
81
-
-
0032510559
-
A lipid associated with the antiphospholipid syndrome regulates endosome structure function
-
Kobayashi, T. et al. A lipid associated with the antiphospholipid syndrome regulates endosome structure and function. Nature 392, 193-197 (1998).
-
(1998)
Nature
, vol.392
, pp. 193-197
-
-
Kobayashi, T.1
-
82
-
-
0037036135
-
A role for lipid shells in targeting proteins to caveolae rafts other lipid domains
-
Anderson, R. G. & Jacobson, K. A role for lipid shells in targeting proteins to caveolae, rafts, and other lipid domains. Science 296, 1821-1825 (2002).
-
(2002)
Science
, vol.296
, pp. 1821-1825
-
-
Anderson, R.G.1
Jacobson, K.2
-
83
-
-
0034595877
-
Essential role for cholesterol in entry of mycobacteria into macrophages
-
Gatfield, J. & Pieters, J. Essential role for cholesterol in entry of mycobacteria into macrophages. Science 288, 1647-1650 (2000).
-
(2000)
Science
, vol.288
, pp. 1647-1650
-
-
Gatfield, J.1
Pieters, J.2
-
84
-
-
6944255361
-
Phosphatidylinositol (4 5) bisphosphate regulates HIV-1 Gag targeting to the plasma membrane
-
Ono, A., Ablan, S. D., Lockett, S. J., Nagashima, K. & Freed, E. O. Phosphatidylinositol (4, 5) bisphosphate regulates HIV-1 Gag targeting to the plasma membrane. Proc. Natl Acad. Sci. USA 101, 14889-14894 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 14889-14894
-
-
Ono, A.1
Ablan, S.D.2
Lockett, S.J.3
Nagashima, K.4
Freed, E.O.5
-
85
-
-
0034864631
-
Multimerization of human immunodeficiency virus type 1 Gag promotes its localization to barges raft-like membrane microdomains
-
Lindwasser, O. W. & Resh, M. D. Multimerization of human immunodeficiency virus type 1 Gag promotes its localization to barges, raft-like membrane microdomains. J. Virol. 75, 7913-7924 (2001).
-
(2001)
J. Virol.
, vol.75
, pp. 7913-7924
-
-
Lindwasser, O.W.1
Resh, M.D.2
-
86
-
-
0034015604
-
Evidence for budding of human immunodeficiency virus type 1 selectively from glycolipid-enriched membrane lipid rafts
-
Nguyen, D. H. & Hildreth, J. E. Evidence for budding of human immunodeficiency virus type 1 selectively from glycolipid-enriched membrane lipid rafts. J. Virol. 74, 3264-3272 (2000).
-
(2000)
J. Virol.
, vol.74
, pp. 3264-3272
-
-
Nguyen, D.H.1
Hildreth, J.E.2
-
87
-
-
7444248910
-
Ceramide a target for antiretroviral therapy
-
Finnegan, C. M. et al. Ceramide, a target for antiretroviral therapy. Proc. Natl Acad. Sci. USA 101, 15452-15457 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 15452-15457
-
-
Finnegan, C.M.1
-
88
-
-
0033593321
-
Influenza viruses select ordered lipid domains during budding from the plasma membrane
-
Scheiffele, P., Rietveld, A., Wilk, T. & Simons, K. Influenza viruses select ordered lipid domains during budding from the plasma membrane. J. Biol. Chem. 274, 2038-2044 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 2038-2044
-
-
Scheiffele, P.1
Rietveld, A.2
Wilk, T.3
Simons, K.4
-
89
-
-
0037159920
-
Virion-associated cholesterol is critical for the maintenance of HIV-1 structure infectivity
-
Campbell, S. M., Crowe, S. M. & Mak, J. Virion-associated cholesterol is critical for the maintenance of HIV-1 structure and infectivity. AIDS 16, 2253-2261 (2002).
-
(2002)
AIDS
, vol.16
, pp. 2253-2261
-
-
Campbell, S.M.1
Crowe, S.M.2
Mak, J.3
-
90
-
-
0037699899
-
Phospholipid analogs against HIV-1 infection disease
-
Morris-Natschke, S. L., Ishaq, K. S. & Kucera, L. S. Phospholipid analogs against HIV-1 infection and disease. Curr. Pharm. Des. 9, 1441-1451 (2003).
-
(2003)
Curr. Pharm. Des.
, vol.9
, pp. 1441-1451
-
-
Morris-Natschke, S.L.1
Ishaq, K.S.2
Kucera, L.S.3
-
91
-
-
0036027897
-
Human immunodeficiency virus host cell lipids. Interesting pathways in research for a new HIV therapy
-
Raulin, J. Human immunodeficiency virus and host cell lipids. Interesting pathways in research for a new HIV therapy. Prog. Lipid. Res. 41, 27-65 (2002).
-
(2002)
Prog. Lipid. Res.
, vol.41
, pp. 27-65
-
-
Raulin, J.1
-
92
-
-
0041920891
-
Tuberculosis toxin blocking phagosome maturation inhibits a novel Ca2+/calmodulin-PI3K hVPS34 cascade
-
Vergne, I., Chua, J. & Deretic, V. Tuberculosis toxin blocking phagosome maturation inhibits a novel Ca2+/calmodulin-PI3K hVPS34 cascade. J. Exp. Med. 198, 653-659 (2003).
-
(2003)
J. Exp. Med.
, vol.198
, pp. 653-659
-
-
Vergne, I.1
Chua, J.2
Deretic, V.3
-
93
-
-
0038354913
-
Identification macrophage-activating activity of glycolipids released from intracellular Mycobacterium bovis BCG
-
Rhoades, E. et al. Identification and macrophage-activating activity of glycolipids released from intracellular Mycobacterium bovis BCG. Mol. Microbiol. 48, 875-888 (2003).
-
(2003)
Mol. Microbiol.
, vol.48
, pp. 875-888
-
-
Rhoades, E.1
-
94
-
-
0037627408
-
Mycobacterium tuberculosis glycosylated phosphatidylinositol causes phagosome maturation arrest
-
Fratti, R. A., Chua, J., Vergne, I. & Deretic, V. Mycobacterium tuberculosis glycosylated phosphatidylinositol causes phagosome maturation arrest. Proc. Natl Acad. Sci. USA 100, 5437-5442 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5437-5442
-
-
Fratti, R.A.1
Chua, J.2
Vergne, I.3
Deretic, V.4
-
95
-
-
2942750147
-
Salmonella modulates vesicular traffic by altering phosphoinositide metabolism
-
Hernandez, L. D., Hueffer, K., Wenk, M. R. & Galan, J. E. Salmonella modulates vesicular traffic by altering phosphoinositide metabolism. Science 304, 1805-1807 (2004).
-
(2004)
Science
, vol.304
, pp. 1805-1807
-
-
Hernandez, L.D.1
Hueffer, K.2
Wenk, M.R.3
Galan, J.E.4
-
96
-
-
0038623770
-
MmpL8 is required for sulfolipid-1 biosynthesis Mycobacterium tuberculosis virulence
-
Converse, S. E. et al. MmpL8 is required for sulfolipid-1 biosynthesis and Mycobacterium tuberculosis virulence. Proc. Natl Acad. Sci. USA 100, 6121-6126 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 6121-6126
-
-
Converse, S.E.1
-
97
-
-
14844349788
-
Sphingosine kinase 1 (SK1) is recruited to nascent phagosomes in human macrophages: Inhibition of SK1 translocation by Mycobacterium tuberculosis
-
Thompson, C. R. et al. Sphingosine kinase 1 (SK1) is recruited to nascent phagosomes in human macrophages: inhibition of SK1 translocation by Mycobacterium tuberculosis. J. Immunol. 174, 3551-3561 (2005).
-
(2005)
J. Immunol.
, vol.174
, pp. 3551-3561
-
-
Thompson, C.R.1
-
98
-
-
20044380517
-
Bacterial injectisomes: Needle length does matter
-
Mota, L. J., Journet, L., Sorg, I., Agrain, C. & Cornelis, G. R. Bacterial injectisomes: needle length does matter. Science 307, 1278 (2005).
-
(2005)
Science
, vol.307
, pp. 1278
-
-
Mota, L.J.1
Journet, L.2
Sorg, I.3
Agrain, C.4
Cornelis, G.R.5
-
99
-
-
15244340430
-
Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis
-
Vergne, I. et al. Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis. Proc. Natl Acad. Sci. USA 102, 4033-4038 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 4033-4038
-
-
Vergne, I.1
-
100
-
-
0034532057
-
Activation of Akt/protein kinase B in epithelial cells by the Salmonella typhimurium effector sigD
-
Steele-Mortimer, O. et al. Activation of Akt/protein kinase B in epithelial cells by the Salmonella typhimurium effector sigD. J. Biol. Chem. 275, 37718-37724 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 37718-37724
-
-
Steele-Mortimer, O.1
-
101
-
-
0024444653
-
Recognition of cluster of differentiation 1 antigens by human CD4-CD8-cytolytic T lymphocytes
-
Porcelli, S. et al. Recognition of cluster of differentiation 1 antigens by human CD4-CD8-cytolytic T lymphocytes. Nature 341, 447-450 (1989).
-
(1989)
Nature
, vol.341
, pp. 447-450
-
-
Porcelli, S.1
-
102
-
-
0028980830
-
CD1-restricted T cell recognition of microbial lipoglycan antigens
-
Sieling, P. A. et al. CD1-restricted T cell recognition of microbial lipoglycan antigens. Science 269, 227-230 (1995).
-
(1995)
Science
, vol.269
, pp. 227-230
-
-
Sieling, P.A.1
-
103
-
-
2542448243
-
CD1: Antigen presentation T cell function
-
Brigl, M. & Brenner, M. B. CD1: Antigen presentation and T cell function. Annu. Rev. Immunol. 22, 817-890 (2004).
-
(2004)
Annu. Rev. Immunol.
, vol.22
, pp. 817-890
-
-
Brigl, M.1
Brenner, M.B.2
-
104
-
-
11844286843
-
CD1 assembly the formation of CD1-antigen complexes
-
Hava, D. L. et al. CD1 assembly and the formation of CD1-antigen complexes. Curr. Opin. Immunol. 17, 88-94 (2005).
-
(2005)
Curr. Opin. Immunol.
, vol.17
, pp. 88-94
-
-
Hava, D.L.1
-
105
-
-
10744232076
-
Saposin C is required for lipid presentation by human CD1b
-
Winau, F. et al. Saposin C is required for lipid presentation by human CD1b. Nature Immunol. 5, 169-174 (2004).
-
(2004)
Nature Immunol.
, vol.5
, pp. 169-174
-
-
Winau, F.1
-
106
-
-
0742270963
-
Lipid-protein interactions: Biosynthetic assembly of CD1 with lipids in the endoplasmic reticulum is evolutionarily conserved
-
Park, J. J. et al. Lipid-protein interactions: biosynthetic assembly of CD1 with lipids in the endoplasmic reticulum is evolutionarily conserved. Proc. Natl Acad. Sci. USA 101, 1022-1026 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1022-1026
-
-
Park, J.J.1
-
107
-
-
0028080105
-
Electrospray ionization mass spectroscopic analysis of human erythrocyte plasma membrane phospholipids
-
Han, X. & Gross, R. W. Electrospray ionization mass spectroscopic analysis of human erythrocyte plasma membrane phospholipids. Proc. Natl Acad. Sci. USA 91, 10635-10639 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 10635-10639
-
-
Han, X.1
Gross, R.W.2
-
108
-
-
0028774677
-
Liquid chromatography/mass spectrometry of phospholipids using electrospray ionization
-
Kim, H. Y. Wang, T C. & Ma, Y. C. Liquid chromatography/mass spectrometry of phospholipids using electrospray ionization. Anal. Chem. 66, 3977-3982 (1994).
-
(1994)
Anal. Chem.
, vol.66
, pp. 3977-3982
-
-
Kim, H.Y.1
Wang, T.C.2
Ma, Y.C.3
-
109
-
-
0028217603
-
Identification of molecular species of glycerophospholipids and sphingomyelin using electrospray mass spectrometry
-
Kerwin, J. L., Tuininga, A. R. & Ericsson, L. H. Identification of molecular species of glycerophospholipids and sphingomyelin using electrospray mass spectrometry. J. Lipid. Res. 35, 1102-1114 (1994).
-
(1994)
J. Lipid. Res.
, vol.35
, pp. 1102-1114
-
-
Kerwin, J.L.1
Tuininga, A.R.2
Ericsson, L.H.3
-
110
-
-
0141974064
-
Electrospray mass spectrometry of phospholipids
-
Pulfer, M. & Murphy, R. C. Electrospray mass spectrometry of phospholipids. Mass Spectrom. Rev. 22, 332-364 (2003).
-
(2003)
Mass Spectrom. Rev.
, vol.22
, pp. 332-364
-
-
Pulfer, M.1
Murphy, R.C.2
-
111
-
-
0141653274
-
Global analyses of cellular lipidomes directly from crude extracts of biological samples by ESI/MS: A bridge to lipidomics
-
Han, X. & Gross, R. W. Global analyses of cellular lipidomes directly from crude extracts of biological samples by ESI/MS: a bridge to lipidomics. J. Lipid. Res. 44, 1071-1079 (2003).
-
(2003)
J. Lipid. Res.
, vol.44
, pp. 1071-1079
-
-
Han, X.1
Gross, R.W.2
-
112
-
-
2442617114
-
Lipid species profiling: A high-throughput approach to identify lipid compositional changes determine the function of genes involved in lipid metabolism signaling
-
Welti, R. & Wang, X. Lipid species profiling: a high-throughput approach to identify lipid compositional changes and determine the function of genes involved in lipid metabolism and signaling. Curr. Opin. Plant Biol. 7, 337-344 (2004).
-
(2004)
Curr. Opin. Plant Biol.
, vol.7
, pp. 337-344
-
-
Welti, R.1
Wang, X.2
-
113
-
-
0030962474
-
Quantitative analysis of biological membrane lipids at the low picomole level by nano-electrospray ionization tandem mass spectrometry
-
Brugger, B., Erben, G., Sandhoff, R., Wieland, F. T. & Lehmann, W. D. Quantitative analysis of biological membrane lipids at the low picomole level by nano-electrospray ionization tandem mass spectrometry. Proc. Natl Acad. Sci. USA 94, 2339-2344 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 2339-2344
-
-
Brugger, B.1
Erben, G.2
Sandhoff, R.3
Wieland, F.T.4
Lehmann, W.D.5
-
114
-
-
0035970197
-
Analysis of sphingosine 1-phosphate ceramides other bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry
-
Sullards, M. C. & Merrill, A. H., Jr. Analysis of sphingosine 1-phosphate, ceramides, and other bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry. Sci STKE PL1 (2001).
-
(2001)
Sci. STKE
-
-
Sullards, M.C.1
Merrill Jr., A.H.2
-
115
-
-
0035425057
-
Quantitative analysis molecular species fingerprinting of triacylglyceride molecular species directly from lipid extracts of biological samples by electrospray ionization tandem mass spectrometry
-
Han, X. & Gross, R. W. Quantitative analysis and molecular species fingerprinting of triacylglyceride molecular species directly from lipid extracts of biological samples by electrospray ionization tandem mass spectrometry. Anal. Biochem. 295, 88-100 (2001).
-
(2001)
Anal. Biochem.
, vol.295
, pp. 88-100
-
-
Han, X.1
Gross, R.W.2
-
116
-
-
0035912783
-
Electrospray ionization mass spectrometry analysis of changes in phospholipids in RBL-2H3 mastocytoma cells during degranulation
-
Ivanova, P. T. et al. Electrospray ionization mass spectrometry analysis of changes in phospholipids in RBL-2H3 mastocytoma cells during degranulation. Proc. Natl Acad. Sci. USA 98, 7152-7157 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 7152-7157
-
-
Ivanova, P.T.1
-
117
-
-
2942592419
-
Toward fingerprinting cellular lipidomes directly from biological samples by two-dimensional electrospray ionization mass spectrometry
-
Han, X., Yang, J., Cheng, H., Ye, H. & Gross, R. W. Toward fingerprinting cellular lipidomes directly from biological samples by two-dimensional electrospray ionization mass spectrometry. Anal. Biochem. 330, 317-331 (2004).
-
(2004)
Anal. Biochem.
, vol.330
, pp. 317-331
-
-
Han, X.1
Yang, J.2
Cheng, H.3
Ye, H.4
Gross, R.W.5
-
118
-
-
0036500210
-
Quantitative profiling of phospholipids by multiple precursor ion scanning on a hybrid quadrupole time-of-flight mass spectrometer
-
Ekroos, K., Chernushevich, I. V., Simons, K. & Shevchenko, A. Quantitative profiling of phospholipids by multiple precursor ion scanning on a hybrid quadrupole time-of-flight mass spectrometer. Anal. Chem. 74, 941-949 (2002).
-
(2002)
Anal. Chem.
, vol.74
, pp. 941-949
-
-
Ekroos, K.1
Chernushevich, I.V.2
Simons, K.3
Shevchenko, A.4
-
119
-
-
0037726628
-
High-resolution field desorption/ionization fourier transform ion cyclotron resonance mass analysis of nonpolar molecules
-
Schaub, T. M., Hendrickson, C. L., Qian, K., Quinn, J. P. & Marshall, A. G. High-resolution field desorption/ionization fourier transform ion cyclotron resonance mass analysis of nonpolar molecules. Anal. Chem. 75, 2172-2176 (2003).
-
(2003)
Anal. Chem.
, vol.75
, pp. 2172-2176
-
-
Schaub, T.M.1
Hendrickson, C.L.2
Qian, K.3
Quinn, J.P.4
Marshall, A.G.5
-
120
-
-
10744230720
-
Phosphoinositide profiling in complex lipid mixtures using electrospray ionization mass spectrometry
-
Wenk, M. R. et al. Phosphoinositide profiling in complex lipid mixtures using electrospray ionization mass spectrometry. Nature Biotechnol. 21, 813-817 (2003).
-
(2003)
Nature Biotechnol.
, vol.21
, pp. 813-817
-
-
Wenk, M.R.1
-
121
-
-
0037086037
-
Characterization direct quantitation of ceramide molecular species from lipid extracts of biological samples by electrospray ionization tandem mass spectrometry
-
Han, X. Characterization and direct quantitation of ceramide molecular species from lipid extracts of biological samples by electrospray ionization tandem mass spectrometry. Anal. Biochem. 302, 199-212 (2002).
-
(2002)
Anal. Biochem.
, vol.302
, pp. 199-212
-
-
Han, X.1
-
122
-
-
7644220905
-
Coupling thin-layer chromatography with vibrational cooling matrix-assisted laser desorption/ionization Fourier transform mass spectrometry for the analysis of ganglioside mixtures
-
Ivleva, V. B. et al. Coupling thin-layer chromatography with vibrational cooling matrix-assisted laser desorption/ionization Fourier transform mass spectrometry for the analysis of ganglioside mixtures. Anal. Chem. 76, 6484-6491 (2004).
-
(2004)
Anal. Chem.
, vol.76
, pp. 6484-6491
-
-
Ivleva, V.B.1
-
123
-
-
0037199955
-
Profiling membrane lipids in plant stress responses. Role of phospholipase D alpha in freezing-induced lipid changes in Arabidopsis
-
Welti, R. et al. Profiling membrane lipids in plant stress responses. Role of phospholipase D alpha in freezing-induced lipid changes in Arabidopsis. J. Biol. Chem. 277, 31994-32002 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 31994-32002
-
-
Welti, R.1
-
124
-
-
0035063286
-
Quantitative determination of phospholipid compositions by ESI-MS: Effects of acyl chain length unsaturation lipid concentration on instrument response
-
Koivusalo, M., Haimi, P., Heikinheimo, L., Kostiainen, R. & Somerharju, P. Quantitative determination of phospholipid compositions by ESI-MS: effects of acyl chain length, unsaturation, and lipid concentration on instrument response. J. Lipid. Res. 42, 663-672 (2001).
-
(2001)
J. Lipid. Res.
, vol.42
, pp. 663-672
-
-
Koivusalo, M.1
Haimi, P.2
Heikinheimo, L.3
Kostiainen, R.4
Somerharju, P.5
-
125
-
-
0035865416
-
Detection of individual phospholipids in lipid mixtures by matrix- assisted laser desorption/ionization time-of-flight mass spectrometry: Phosphatidylcholine prevents the detection of further species
-
Petkovic, M. et al. Detection of individual phospholipids in lipid mixtures by matrix- assisted laser desorption/ionization time-of-flight mass spectrometry: phosphatidylcholine prevents the detection of further species. Anal. Biochem. 289, 202-216 (2001).
-
(2001)
Anal. Biochem.
, vol.289
, pp. 202-216
-
-
Petkovic, M.1
-
126
-
-
0038635425
-
Limits for the detection of (poly)phosphoinositides by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS)
-
Muller, M. et al. Limits for the detection of (poly)phosphoinositides by matrix-assisted laser desorption and ionization time-of-flight mass spectrometry (MALDI-TOF MS). Chem. Phys. Lipids 110, 151-164 (2001).
-
(2001)
Chem. Phys. Lipids
, vol.110
, pp. 151-164
-
-
Muller, M.1
-
127
-
-
14744291867
-
A shotgun tandem mass spectrometric analysis of phospholipids with normal-phase and/or reverse-phase liquid chromatography/electrospray ionization mass spectrometry
-
Houjou, T., Yamatani, K., Imagawa, M., Shimizu, T. & Taguchi, R. A shotgun tandem mass spectrometric analysis of phospholipids with normal-phase and/or reverse-phase liquid chromatography/electrospray ionization mass spectrometry. Rapid Commun. Mass Spectrom. 19, 654-666 (2005).
-
(2005)
Rapid Commun. Mass Spectrom.
, vol.19
, pp. 654-666
-
-
Houjou, T.1
Yamatani, K.2
Imagawa, M.3
Shimizu, T.4
Taguchi, R.5
-
128
-
-
16244410140
-
Automated quantitative analysis of complex lipidomes by liquid chromatography/mass spectrometry
-
Hermansson, M., Uphoff, A., Kakela, R. & Somerharju, P. Automated quantitative analysis of complex lipidomes by liquid chromatography/mass spectrometry. Anal. Chem. 77, 2166-2175 (2005).
-
(2005)
Anal. Chem.
, vol.77
, pp. 2166-2175
-
-
Hermansson, M.1
Uphoff, A.2
Kakela, R.3
Somerharju, P.4
-
129
-
-
2942527049
-
Lipomic profiling in drug discovery development clinical trial evaluation
-
Watkins, S. M. Lipomic profiling in drug discovery, development and clinical trial evaluation. Curr. Opin. Drug Discov. Devel. 7, 112-117 (2004).
-
(2004)
Curr. Opin. Drug Discov. Devel.
, vol.7
, pp. 112-117
-
-
Watkins, S.M.1
-
130
-
-
0030041158
-
Quantitative high-performance liquid chromatography analysis of plant phospholipids glycolipids using light-scattering detection
-
Picchioni, G. A., Watada, A. E. & Whitaker, B. D. Quantitative high-performance liquid chromatography analysis of plant phospholipids and glycolipids using light-scattering detection. Lipids 31, 217-221 (1996).
-
(1996)
Lipids
, vol.31
, pp. 217-221
-
-
Picchioni, G.A.1
Watada, A.E.2
Whitaker, B.D.3
-
131
-
-
0037083398
-
Nonradioactive analysis of phosphatidylinositides and other anionic phospholipids by anion-exchange high-performance liquid chromatography with suppressed conductivity detection
-
Nasuhoglu, C. et al. Nonradioactive analysis of phosphatidylinositides and other anionic phospholipids by anion-exchange high-performance liquid chromatography with suppressed conductivity detection. Anal. Biochem. 301, 243-254 (2002).
-
(2002)
Anal. Biochem.
, vol.301
, pp. 243-254
-
-
Nasuhoglu, C.1
-
132
-
-
0037333361
-
Separation of phospholipids in microfluidic chip device: Application to high-throughput screening assays for lipid-modifying enzymes
-
Lin, S., Fischl, A. S., Bi, X. & Parce, W. Separation of phospholipids in microfluidic chip device: application to high-throughput screening assays for lipid-modifying enzymes. Anal. Biochem. 314, 97-107 (2003).
-
(2003)
Anal. Biochem.
, vol.314
, pp. 97-107
-
-
Lin, S.1
Fischl, A.S.2
Bi, X.3
Parce, W.4
-
133
-
-
0142185928
-
Capillary electrophoresis of cardiolipin with on-line dye interaction spectrophotometric detection
-
Qi, L., Danielson, N. D., Dai, Q. & Lee, R. M. Capillary electrophoresis of cardiolipin with on-line dye interaction and spectrophotometric detection. Electrophoresis 24, 1680-1686 (2003).
-
(2003)
Electrophoresis
, vol.24
, pp. 1680-1686
-
-
Qi, L.1
Danielson, N.D.2
Dai, Q.3
Lee, R.M.4
-
134
-
-
0345168944
-
Personal metabolomics as a next generation nutritional assessment
-
German, J. B., Roberts, M. A. & Watkins, S. M. Personal metabolomics as a next generation nutritional assessment. J. Nutr. 133, 4260-4266 (2003).
-
(2003)
J. Nutr.
, vol.133
, pp. 4260-4266
-
-
German, J.B.1
Roberts, M.A.2
Watkins, S.M.3
-
136
-
-
0017617172
-
Effect of a single cis double bond on the structures of a phospholipid bilayer
-
Seelig, A. & Seelig, J. Effect of a single cis double bond on the structures of a phospholipid bilayer. Biochemistry 16, 45-50 (1977).
-
(1977)
Biochemistry
, vol.16
, pp. 45-50
-
-
Seelig, A.1
Seelig, J.2
-
137
-
-
0036289241
-
Novel NMR tools to study structure dynamics of biomembranes
-
Gawrisch, K., Eldho, N. V. & Polozov, I. V. Novel NMR tools to study structure and dynamics of biomembranes. Chem. Phys. Lipids 116, 135-151 (2002).
-
(2002)
Chem. Phys. Lipids
, vol.116
, pp. 135-151
-
-
Gawrisch, K.1
Eldho, N.V.2
Polozov, I.V.3
-
138
-
-
7044224839
-
The protein-lipid interface: Perspectives from magnetic resonance crystal structures
-
Marsh, D. & Pali, T. The protein-lipid interface: perspectives from magnetic resonance and crystal structures. Biochim. Biophys. Acta 1666, 118-141 (2004).
-
(2004)
Biochim. Biophys. Acta
, vol.1666
, pp. 118-141
-
-
Marsh, D.1
Pali, T.2
-
139
-
-
0018083022
-
Immobilized lipid in acetylcholine receptor-rich membranes from Torpedo marmorata
-
Marsh, D. & Barrantes, F. J. Immobilized lipid in acetylcholine receptor-rich membranes from Torpedo marmorata. Proc. Natl Acad. Sci. USA 75, 4329-4333 (1978).
-
(1978)
Proc. Natl. Acad. Sci. USA
, vol.75
, pp. 4329-4333
-
-
Marsh, D.1
Barrantes, F.J.2
-
140
-
-
0035808040
-
The complex and intriguing lives of PIP2 with ion channels and transporters
-
Hilgemann, D. W., Feng, S. & Nasuhoglu, C. The complex and intriguing lives of PIP2 with ion channels and transporters. Sci. STKE. RE19 (2001).
-
(2001)
Sci. STKE
-
-
Hilgemann, D.W.1
Feng, S.2
Nasuhoglu, C.3
-
141
-
-
0032986388
-
Solid-state nuclear magnetic resonance investigation of protein and polypeptide structure
-
Fu, R. & Cross, T. A. Solid-state nuclear magnetic resonance investigation of protein and polypeptide structure. Annu. Rev. Biophys. Biomol. Struct. 28, 235-268 (1999).
-
(1999)
Annu. Rev. Biophys. Biomol. Struct.
, vol.28
, pp. 235-268
-
-
Fu, R.1
Cross, T.A.2
-
142
-
-
0034634448
-
An NMR-based metabonomic approach to investigate the biochemical consequences of genetic strain differences: Application to the C57BL10J Alpk: ApfCD mouse
-
Gavaghan, C. L., Holmes, E., Lenz, E., Wilson, I. D. & Nicholson, J. K. An NMR-based metabonomic approach to investigate the biochemical consequences of genetic strain differences: application to the C57BL10J and Alpk: ApfCD mouse. FEBS Lett. 484, 169-174 (2000).
-
(2000)
FEBS Lett.
, vol.484
, pp. 169-174
-
-
Gavaghan, C.L.1
Holmes, E.2
Lenz, E.3
Wilson, I.D.4
Nicholson, J.K.5
-
143
-
-
0043069547
-
Opinion: Understanding 'global' systems biology: Metabonomics the continuum of metabolism
-
Nicholson, J. K. & Wilson, I. D. Opinion: understanding 'global' systems biology: metabonomics and the continuum of metabolism. Nature Rev. Drug Discov. 2, 668-676 (2003).
-
(2003)
Nature Rev. Drug Discov.
, vol.2
, pp. 668-676
-
-
Nicholson, J.K.1
Wilson, I.D.2
-
144
-
-
2642563771
-
Phosphoinositide signaling; from affinity probes to pharmaceutical targets
-
Prestwich, G. D. Phosphoinositide signaling; from affinity probes to pharmaceutical targets. Chem. Biol. 11, 619-637 (2004).
-
(2004)
Chem. Biol.
, vol.11
, pp. 619-637
-
-
Prestwich, G.D.1
-
145
-
-
4644285834
-
Assaying phosphoinositide phosphatases
-
Taylor, G. S. & Dixon, J. E. Assaying phosphoinositide phosphatases. Methods Mol. Biol. 284, 217-228 (2004).
-
(2004)
Methods Mol. Biol.
, vol.284
, pp. 217-228
-
-
Taylor, G.S.1
Dixon, J.E.2
-
146
-
-
0035860499
-
Global analysis of protein activities using proteome chips
-
Zhu, H. et al. Global analysis of protein activities using proteome chips. Science 293, 2101-2105 (2001).
-
(2001)
Science
, vol.293
, pp. 2101-2105
-
-
Zhu, H.1
-
147
-
-
0034157389
-
Role of membrane organization membrane domains in endocytic lipid trafficking
-
Mukherjee, S. & Maxfield, F. R. Role of membrane organization and membrane domains in endocytic lipid trafficking. Traffic 1, 203-211 (2000).
-
(2000)
Traffic
, vol.1
, pp. 203-211
-
-
Mukherjee, S.1
Maxfield, F.R.2
-
148
-
-
1542327659
-
Transbilayer movement of phospholipids in biogenic membranes
-
Kol, M. A., de Kroon, A. I., Killian, J. A. & de, K. B. Transbilayer movement of phospholipids in biogenic membranes. Biochemistry 43, 2673-2681 (2004).
-
(2004)
Biochemistry
, vol.43
, pp. 2673-2681
-
-
Kol, M.A.1
de Kroon, A.I.2
Killian, J.A.3
de, K.B.4
-
149
-
-
0242286219
-
Assembly of endocytosis-associated proteins on liposomes
-
Wenk, M. R. & De Camilli, P. Assembly of endocytosis-associated proteins on liposomes. Meth. Enzymol. 372, 248-260 (2003).
-
(2003)
Meth. Enzymol.
, vol.372
, pp. 248-260
-
-
Wenk, M.R.1
De Camilli, P.2
-
150
-
-
18244392475
-
Identification of ARAP3 a novel PI3K effector regulating both Arf Rho GTPases by selective capture on phosphoinositide affinity matrices
-
Krugmann, S. et al. Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices. Mol. Cell 9, 95-108 (2002).
-
(2002)
Mol. Cell
, vol.9
, pp. 95-108
-
-
Krugmann, S.1
-
151
-
-
0033973792
-
A colorimetric assay for rapid screening of antimicrobial peptides
-
Kolusheva, S., Boyer, L. & Jelinek, R. A colorimetric assay for rapid screening of antimicrobial peptides. Nature Biotechnol. 18, 225-227 (2000).
-
(2000)
Nature Biotechnol.
, vol.18
, pp. 225-227
-
-
Kolusheva, S.1
Boyer, L.2
Jelinek, R.3
-
152
-
-
0034739859
-
Localized biphasic changes in phosphatidylinositol-4 5-bisphosphate at sites of phagocytosis
-
Botelho, R. J. et al. Localized biphasic changes in phosphatidylinositol-4, 5-bisphosphate at sites of phagocytosis. J. Cell Biol. 151, 1353-1368 (2000).
-
(2000)
J. Cell Biol.
, vol.151
, pp. 1353-1368
-
-
Botelho, R.J.1
-
153
-
-
33845261493
-
A rapid method of total lipid extraction purification
-
Bligh, E. G. & Dyer, W. J. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37, 911-917 (1959).
-
(1959)
Can. J. Biochem. Physiol.
, vol.37
, pp. 911-917
-
-
Bligh, E.G.1
Dyer, W.J.2
-
154
-
-
78651052311
-
Preparation of lipide extracts from brain tissue
-
Folch, J., Ascoli, I., Lees, M., Meath, J. A. & Le, B. N. Preparation of lipide extracts from brain tissue. J. Biol. Chem. 191, 833-841 (1951).
-
(1951)
J. Biol. Chem.
, vol.191
, pp. 833-841
-
-
Folch, J.1
Ascoli, I.2
Lees, M.3
Meath, J.A.4
Le, B.N.5
-
155
-
-
32644460653
-
-
(eds. Feng, L. & Prestwich, G. D.) (Dekker-CRC, New York, in the press)
-
Wenk, M. R. & De Camilli, P. in Functional Lipidomics (eds. Feng, L. & Prestwich, G. D.) (Dekker-CRC, New York, in the press).
-
Functional Lipidomics
-
-
Wenk, M.R.1
De Camilli, P.2
-
156
-
-
20444419500
-
A comprehensive classification system for lipids
-
Fahy, E. et al. A comprehensive classification system for lipids. J. Lipid Res. 46, 839-862 (2005).
-
(2005)
J. Lipid Res.
, vol.46
, pp. 839-862
-
-
Fahy, E.1
-
157
-
-
1842428733
-
Computational lipidomics: A multiplexed analysis of dynamic changes in membrane lipid composition during signal transduction
-
Forrester, J. S., Milne, S. B., Ivanova, P. T. & Brown, H. A. Computational lipidomics: a multiplexed analysis of dynamic changes in membrane lipid composition during signal transduction. Mol. Pharmacol. 65, 813-821 (2004).
-
(2004)
Mol. Pharmacol.
, vol.65
, pp. 813-821
-
-
Forrester, J.S.1
Milne, S.B.2
Ivanova, P.T.3
Brown, H.A.4
-
158
-
-
21744442925
-
Mediator-lipidomics: Databases and search algorithms for PUFA-derived mediators
-
Lu, Y., Hong, S., Tjonahen, E. & Serhan, C. N. Mediator-lipidomics: databases and search algorithms for PUFA-derived mediators. J. Lipid Res. 46, 790-802 (2005).
-
(2005)
J. Lipid Res.
, vol.46
, pp. 790-802
-
-
Lu, Y.1
Hong, S.2
Tjonahen, E.3
Serhan, C.N.4
-
159
-
-
13444283465
-
Simulation validation of modelled sphingolipid metabolism in Saccharomyces cerevisiae
-
varez-Vasquez, F. et al. Simulation and validation of modelled sphingolipid metabolism in Saccharomyces cerevisiae. Nature 433, 425-430 (2005).
-
(2005)
Nature
, vol.433
, pp. 425-430
-
-
Varez-Vasquez, F.1
-
161
-
-
8744219635
-
Pleckstrin homology domains: Not just for phosphoinositides
-
Lemmon, M. A. Pleckstrin homology domains: not just for phosphoinositides. Biochem. Soc. Trans. 32, 707-711 (2004).
-
(2004)
Biochem. Soc. Trans.
, vol.32
, pp. 707-711
-
-
Lemmon, M.A.1
-
162
-
-
2442647715
-
Differential metabolic networks unravel the effects of silent plant phenotypes
-
Weckwerth, W., Loureiro, M. E., Wenzel, K. & Fiehn, O. Differential metabolic networks unravel the effects of silent plant phenotypes. Proc. Natl Acad. Sci. USA 101, 7809-7814 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 7809-7814
-
-
Weckwerth, W.1
Loureiro, M.E.2
Wenzel, K.3
Fiehn, O.4
-
163
-
-
0036195958
-
Metabolic control analysis in drug discovery disease
-
Cascante, M. et al. Metabolic control analysis in drug discovery and disease. Nature Biotechnol. 20, 243-249 (2002).
-
(2002)
Nature Biotechnol.
, vol.20
, pp. 243-249
-
-
Cascante, M.1
-
164
-
-
0032102323
-
Diacylglycerols phosphatidates: Which molecular species are intracellular messengers?
-
Hodgkin, M. N. et al. Diacylglycerols and phosphatidates: which molecular species are intracellular messengers? Trends Biochem. Sci. 23, 200-204 (1998).
-
(1998)
Trends Biochem. Sci.
, vol.23
, pp. 200-204
-
-
Hodgkin, M.N.1
-
165
-
-
9144251640
-
A molecular defect in intracellular lipid signaling in human neutrophils in localized aggressive periodontal tissue damage
-
Gronert, K. et al. A molecular defect in intracellular lipid signaling in human neutrophils in localized aggressive periodontal tissue damage. J. Immunol. 172, 1856-1861 (2004).
-
(2004)
J. Immunol.
, vol.172
, pp. 1856-1861
-
-
Gronert, K.1
-
166
-
-
0035957921
-
Induction of apoptosis through B-cell receptor cross-linking occurs via de novo generated C16-ceramide involves mitochondria
-
Kroesen, B. J. et al. Induction of apoptosis through B-cell receptor cross-linking occurs via de novo generated C16-ceramide and involves mitochondria. J. Biol. Chem. 276, 13606-13614 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 13606-13614
-
-
Kroesen, B.J.1
-
167
-
-
7244244035
-
Defects in cell growth regulation by C18:0-ceramide and longevity assurance gene 1 in human head and neck squamous cell carcinomas
-
Koybasi, S. et al. Defects in cell growth regulation by C18:0-ceramide and longevity assurance gene 1 in human head and neck squamous cell carcinomas. J. Biol. Chem. 279, 44311-44319 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 44311-44319
-
-
Koybasi, S.1
-
168
-
-
0035415869
-
Chemical genetic approaches for the elucidation of signaling pathways
-
Alaimo, P. J., Shogren-Knaak, M. A. & Shokat, K. M. Chemical genetic approaches for the elucidation of signaling pathways. Curr. Opin. Chem. Biol. 5, 360-367 (2001).
-
(2001)
Curr. Opin. Chem. Biol.
, vol.5
, pp. 360-367
-
-
Alaimo, P.J.1
Shogren-Knaak, M.A.2
Shokat, K.M.3
-
169
-
-
0037452981
-
Novel functions of the phosphatidylinositol metabolic pathway discovered by a chemical genomics screen with wortmannin
-
Zewail, A. et al. Novel functions of the phosphatidylinositol metabolic pathway discovered by a chemical genomics screen with wortmannin. Proc. Natl Acad. Sci. USA 100, 3345-3350 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 3345-3350
-
-
Zewail, A.1
-
170
-
-
4544312369
-
The transcriptional responses of Mycobacterium tuberculosis to inhibitors of metabolism: Novel insights into drug mechanisms of action
-
Boshoff, H. I. et al. The transcriptional responses of Mycobacterium tuberculosis to inhibitors of metabolism: novel insights into drug mechanisms of action. J. Biol. Chem. 279, 40174-40184 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 40174-40184
-
-
Boshoff, H.I.1
-
171
-
-
9144251572
-
T cell activation by lipopeptide antigens
-
Moody, D. B. et al. T cell activation by lipopeptide antigens. Science 303, 527-531 (2004).
-
(2004)
Science
, vol.303
, pp. 527-531
-
-
Moody, D.B.1
-
172
-
-
13444280215
-
CD36 is a sensor of diacylglycerides
-
Hoebe, K. et al. CD36 is a sensor of diacylglycerides. Nature 433, 523-527 (2005).
-
(2005)
Nature
, vol.433
, pp. 523-527
-
-
Hoebe, K.1
-
173
-
-
0025325535
-
Structure of a cannabinoid receptor functional expression of the cloned cDNA
-
Matsuda, L. A,, Lolait, S. J., Brownstein, M. J., Young, A. C. & Bonner, T. I. Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346, 561-564 (1990).
-
(1990)
Nature
, vol.346
, pp. 561-564
-
-
Matsuda, L.A.1
Lolait, S.J.2
Brownstein, M.J.3
Young, A.C.4
Bonner, T.I.5
-
174
-
-
0027078685
-
Isolation structure of a brain constituent that binds to the cannabinoid receptor
-
Devane, W. A. et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258, 1946-1949 (1992).
-
(1992)
Science
, vol.258
, pp. 1946-1949
-
-
Devane, W.A.1
-
176
-
-
0036197530
-
Binding of a Pleckstrin homology domain protein to phosphoinositide in membranes: A miniaturized FRET-based assay for drug screening
-
Hamman, B. D., Pollok, B. A., Bennett, T., Allen, J. & Heim, R. Binding of a Pleckstrin homology domain protein to phosphoinositide in membranes: a miniaturized FRET-based assay for drug screening. J. Biomol. Screen. 7, 45-55 (2002).
-
(2002)
J. Biomol. Screen.
, vol.7
, pp. 45-55
-
-
Hamman, B.D.1
Pollok, B.A.2
Bennett, T.3
Allen, J.4
Heim, R.5
-
177
-
-
0037442448
-
Nonradioactive methods for the assay of phosphoinositide 3-kinases phosphoinositide phosphatases selective detection of signaling lipids in cell tissue extracts
-
Gray, A., Olsson, H., Batty, I. H., Priganica, L. & Peter Downes, C. Nonradioactive methods for the assay of phosphoinositide 3-kinases and phosphoinositide phosphatases and selective detection of signaling lipids in cell and tissue extracts. Anal. Biochem. 313, 234-245 (2003).
-
(2003)
Anal. Biochem.
, vol.313
, pp. 234-245
-
-
Gray, A.1
Olsson, H.2
Batty, I.H.3
Priganica, L.4
Peter Downes, C.5
-
178
-
-
8544253237
-
Assignment of endogenous substrates to enzymes by global metabolite profiling
-
Saghatelian, A. et al. Assignment of endogenous substrates to enzymes by global metabolite profiling. Biochemistry 43, 14332-14339 (2004).
-
(2004)
Biochemistry
, vol.43
, pp. 14332-14339
-
-
Saghatelian, A.1
-
179
-
-
1242330282
-
A ratiometric expressible FRET sensor for phosphoinositides displays a signal change in highly dynamic membrane structures in fibroblasts
-
Cicchetti, G., Biernacki, M., Farquharson, J. & Allen, P. G. A ratiometric expressible FRET sensor for phosphoinositides displays a signal change in highly dynamic membrane structures in fibroblasts. Biochemistry 43, 1930-1949 (2004).
-
(2004)
Biochemistry
, vol.43
, pp. 1930-1949
-
-
Cicchetti, G.1
Biernacki, M.2
Farquharson, J.3
Allen, P.G.4
-
180
-
-
4644260485
-
Fluorescent biosensor for quantitative real-time measurements of inositol 1 4 5-trisphosphate in single living cells
-
Tanimura, A., Nezu, A., Morita, T., Turner, R. J. & Tojyo, Y. Fluorescent biosensor for quantitative real-time measurements of inositol 1, 4, 5-trisphosphate in single living cells. J. Biol. Chem. 279, 38095-38098 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 38095-38098
-
-
Tanimura, A.1
Nezu, A.2
Morita, T.3
Turner, R.J.4
Tojyo, Y.5
-
181
-
-
3142737966
-
Chemical genetic screening identifies sulfonamides that raise organellar pH interfere with membrane traffic
-
Nieland, T. J. et al. Chemical genetic screening identifies sulfonamides that raise organellar pH and interfere with membrane traffic. Traffic. 5, 478-492 (2004).
-
(2004)
Traffic
, vol.5
, pp. 478-492
-
-
Nieland, T.J.1
-
182
-
-
0038016550
-
Antagonists of myo-inositol 3 4 5 6-tetrakisphosphate allow repeated epithelial chloride secretion
-
Rudolf, M. T., Dinkel, C., Traynor-Kaplan, A. E. & Schultz, C. Antagonists of myo-inositol 3, 4, 5, 6-tetrakisphosphate allow repeated epithelial chloride secretion. Bioorg. Med. Chem. 11, 3315-3329 (2003).
-
(2003)
Bioorg. Med. Chem.
, vol.11
, pp. 3315-3329
-
-
Rudolf, M.T.1
Dinkel, C.2
Traynor-Kaplan, A.E.3
Schultz, C.4
-
183
-
-
10844275607
-
Phosphorylation of proteins by inositol pyrophosphates
-
Saiardi, A., Bhandari, R., Resnick, A. C., Snowman, A. M. & Snyder, S. H. Phosphorylation of proteins by inositol pyrophosphates. Science 306, 2101-2105 (2004).
-
(2004)
Science
, vol.306
, pp. 2101-2105
-
-
Saiardi, A.1
Bhandari, R.2
Resnick, A.C.3
Snowman, A.M.4
Snyder, S.H.5
-
184
-
-
1642285882
-
Enzymatic release of antitumor ether lipids by specific phospholipase A2 activation of liposome-forming prodrugs
-
Andresen, T. L., Davidsen, J,, Begtrup, M., Mouritsen, O. G. & Jorgensen, K. Enzymatic release of antitumor ether lipids by specific phospholipase A2 activation of liposome-forming prodrugs. J. Med. Chem. 47, 1694-1703 (2004).
-
(2004)
J. Med. Chem.
, vol.47
, pp. 1694-1703
-
-
Andresen, T.L.1
Davidsen, J.2
Begtrup, M.3
Mouritsen, O.G.4
Jorgensen, K.5
-
185
-
-
0036314168
-
HPLC-MS/MS analysis of the products generated from all-trans-retinoic acid using recombinant human CYP26A
-
Chithalen, J. V., Luu, L., Petkovich, M. & Jones, G. HPLC-MS/MS analysis of the products generated from all-trans-retinoic acid using recombinant human CYP26A. J. Lipid Res. [b 43, 1133-1142 (2002).
-
(2002)
J. Lipid Res.
, vol.43
, pp. 1133-1142
-
-
Chithalen, J.V.1
Luu, L.2
Petkovich, M.3
Jones, G.4
-
186
-
-
20544466649
-
Metabonomics in toxicology: A review
-
Robertson, D. G. Metabonomics in toxicology: a review. Toxicol. Sci. 85, 809-822 (2005).
-
(2005)
Toxicol. Sci.
, vol.85
, pp. 809-822
-
-
Robertson, D.G.1
-
187
-
-
0036905921
-
Amyloid beta-peptide (1-42)-induced oxidative stress neurotoxicity: Implications for neurodegeneration in Alzheimer's disease brain. A review
-
Butterfield, D. A. Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review. Free Radic. Res. 36, 1307-1313 (2002).
-
(2002)
Free Radic. Res.
, vol.36
, pp. 1307-1313
-
-
Butterfield, D.A.1
-
188
-
-
0842346368
-
Isoprostanes related products of lipid peroxidation in neurodegenerative diseases
-
Montine, K. S. et al. Isoprostanes and related products of lipid peroxidation in neurodegenerative diseases. Chem. Phys. Lipids 128, 117-124 (2004).
-
(2004)
Chem. Phys. Lipids
, vol.128
, pp. 117-124
-
-
Montine, K.S.1
-
189
-
-
0035011337
-
Raised levels of F(2)-isoprostanes and prostaglandin F(2alpha) in different rheumatic diseases
-
Basu, S., Whiteman, M., Mattey, D. L. & Halliwell, B. Raised levels of F(2)-isoprostanes and prostaglandin F(2alpha) in different rheumatic diseases. Ann. Rheum. Dis. 60, 627-631 (2001).
-
(2001)
Ann. Rheum. Dis.
, vol.60
, pp. 627-631
-
-
Basu, S.1
Whiteman, M.2
Mattey, D.L.3
Halliwell, B.4
-
190
-
-
18144437430
-
Direct observation of lipid hydroperoxides in phospholipid vesicles by electrospray mass spectrometry
-
Spickett, C. M., Pitt, A. R. & Brown, A. J. Direct observation of lipid hydroperoxides in phospholipid vesicles by electrospray mass spectrometry. Free Radic. Biol. Med. 25, 613-620 (1998).
-
(1998)
Free Radic. Biol. Med.
, vol.25
, pp. 613-620
-
-
Spickett, C.M.1
Pitt, A.R.2
Brown, A.J.3
-
191
-
-
5444238154
-
High-resolution analysis by nano-electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry for the identification of molecular species of phospholipids their oxidized metabolites
-
Ishida, M. et al. High-resolution analysis by nano-electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry for the identification of molecular species of phospholipids and their oxidized metabolites. Rapid Commun. Mass Spectrom. 18, 2486-2494 (2004).
-
(2004)
Rapid Commun. Mass Spectrom.
, vol.18
, pp. 2486-2494
-
-
Ishida, M.1
-
192
-
-
13044265838
-
Structurally similar oxidized phospholipids differentially regulate endothelial binding of monocytes neutrophils
-
Leitinger, N. et al. Structurally similar oxidized phospholipids differentially regulate endothelial binding of monocytes and neutrophils. Proc. Natl Acad. Sci. USA 96, 12010-12015 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 12010-12015
-
-
Leitinger, N.1
-
193
-
-
0034306169
-
Cardiolipin provides specificity for targeting of tBid to mitochondria
-
Lutter, M. et al. Cardiolipin provides specificity for targeting of tBid to mitochondria. Nature Cell Biol. 2, 754-761 (2000).
-
(2000)
Nature Cell Biol.
, vol.2
, pp. 754-761
-
-
Lutter, M.1
-
194
-
-
0036644558
-
A role for oxidative stress in apoptosis: Oxidation externalization of phosphatidylserine is required for macrophage clearance of cells undergoing Fas-mediated apoptosis
-
Kagan, V. E. et al. A role for oxidative stress in apoptosis: oxidation and externalization of phosphatidylserine is required for macrophage clearance of cells undergoing Fas-mediated apoptosis. J. Immunol. 169, 487-499 (2002).
-
(2002)
J. Immunol.
, vol.169
, pp. 487-499
-
-
Kagan, V.E.1
-
195
-
-
15444364395
-
Molecular circuits of resolution: Formation and actions of resolvins and protectins
-
Bannenberg, G. L. et al. Molecular circuits of resolution: formation and actions of resolvins and protectins. J. Immunol. 174, 4345-4355 (2005).
-
(2005)
J. Immunol.
, vol.174
, pp. 4345-4355
-
-
Bannenberg, G.L.1
-
196
-
-
0036534398
-
A comparison of two algorithms for warping of analytical signals
-
Pravdova, V., Walczak, B. & Massart, D. L. A comparison of two algorithms for warping of analytical signals. Anal. Chim. Acta 456, 77-92 (2002).
-
(2002)
Anal. Chim. Acta
, vol.456
, pp. 77-92
-
-
Pravdova, V.1
Walczak, B.2
Massart, D.L.3
-
198
-
-
0036082665
-
PIP(2) and proteins: Interactions, organization, and information flow
-
McLaughlin, S., Wang, J,, Gambhir, A. & Murray, D. PIP(2) and proteins: interactions, organization, and information flow. Annu. Rev. Biophys. Biomol. Struct. 31, 151-175 (2002).
-
(2002)
Annu. Rev. Biophys. Biomol. Struct.
, vol.31
, pp. 151-175
-
-
McLaughlin, S.1
Wang, J.2
Gambhir, A.3
Murray, D.4
-
199
-
-
9644294471
-
Structural basis for lipid modulation of nicotinic acetylcholine receptor function
-
Barrantes, F. J. Structural basis for lipid modulation of nicotinic acetylcholine receptor function. Brain Res. Brain Res. Rev. 47, 71-95 (2004).
-
(2004)
Brain Res. Brain Res. Rev.
, vol.47
, pp. 71-95
-
-
Barrantes, F.J.1
-
200
-
-
0038281249
-
Phosphoinositide recognition domains
-
Lemmon, M. A. Phosphoinositide recognition domains. Traffic 4, 201-213 (2003).
-
(2003)
Traffic
, vol.4
, pp. 201-213
-
-
Lemmon, M.A.1
|