The transcriptional responses of Mycobacterium tuberculosis to inhibitors of metabolism. Novel insights into drug mechanisms of action

Journal of Biological Chemistry

Volumn 279, Issue 38, 2004, Pages 40174-40184

  Boshoff, Helena I M ^a,d   Myers, Timothy G ^a   Copp, Brent R ^b   McNeil, Michael R ^c   Wilson, Michael A ^a   Barry III, Clifton E ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c Department of Environmental and Radiological Health Sciences   (United States)

^d Twinbrook 11 Facility   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DATA REDUCTION; DETOXIFICATION; DRUG PRODUCTS; GENES; METABOLISM; PURIFICATION;

DATASETS; PATHOGEN; TUBERCULOSIS;

BACTERIA;

5,5' DITHIOBIS(2 NITROBENZOIC ACID); ACRIDONE DERIVATIVE; AMIKACIN; AMOXICILLIN; ANTIINFECTIVE AGENT; CAPREOMYCIN; CEFALEXIN; CERULENIN; CLOFAZIMINE; CLOTRIMAZOLE; DIAMINE DERIVATIVE; ECONAZOLE; ETHAMBUTOL; ETHIONAMIDE; ISONIAZID; LEVOFLOXACIN; MENADIONE; MITOMYCIN C; OFLOXACIN; PALMITIC ACID; PHENOTHIAZINE DERIVATIVE; PYRAZINAMIDE; ROXITHROMYCIN; STREPTOMYCIN; SUCCINIC ACID; TETRACYCLINE; THIOLACTOMYCIN; UNINDEXED DRUG; VERAPAMIL; ZINC SULFATE;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL METABOLISM; CONTROLLED STUDY; DETOXIFICATION; DRUG MECHANISM; DRUG POTENCY; GENE CLUSTER; GENETIC TRANSCRIPTION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PURIFICATION; TRANSCRIPTION REGULATION; VALIDATION PROCESS;

ANTIPSYCHOTIC AGENTS; ANTITUBERCULAR AGENTS; AZOLES; CELL WALL; DNA GYRASE; DRUG DESIGN; ELECTRON TRANSPORT; ENERGY METABOLISM; ENZYME INHIBITORS; ETHAMBUTOL; FLUOROQUINOLONES; GENE EXPRESSION REGULATION, BACTERIAL; GENOME, BACTERIAL; MYCOBACTERIUM TUBERCULOSIS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTHIAZINES; TRANS-ACTIVATION (GENETICS);

ACTINOBACTERIA (CLASS); BACTERIA (MICROORGANISMS); MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; PROKARYOTA; UNCULTURED ACTINOMYCETE;

EID: 4544312369     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M406796200     Document Type: Article

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