Limits for the detection of (poly-)phosphoinositides by matrix-assisted laser desorption and ionization time-of-flight mass spectrometry (MALDI-TOF MS)

Chemistry and Physics of Lipids

Volumn 110, Issue 2, 2001, Pages 151-164

  Müller, Matthias ^a   Schiller, Jürgen ^a   Petković, Marijana ^a   Oehrl, Wolf ^b   Heinze, Regina ^b   Wetzker, Reinhard ^b   Arnold, Klaus ^a   Arnhold, Jürgen ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Detection limits; Lipid analysis; MALDI TOF mass spectrometry; Phosphoinositides

Indexed keywords

GENTISIC ACID; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITOL; PHOSPHOLIPID;

ARTICLE; DESORPTION; DEVICE; IONIZATION; LASER; LIPID ANALYSIS; MASS SPECTROMETRY; MOLECULAR WEIGHT; PHOSPHORYLATION; PRIORITY JOURNAL;

PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHORYLATION; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 0038635425     PISSN: 00093084     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-3084(01)00132-3     Document Type: Article

References (41)

1. Asbury G.R., Al-Saad K., Siems W.F., Hannan R.M., Hill H.H. Analysis of triacylglycerols and whole oils by matrix-assisted laser desorption/ionization time of flight mass spectrometry. J. Am. Soc. Mass. Spectrom. 10:1999;983-991.
2. Bahr U., Stahl-Zeng J., Karas M. Delayed extraction time-of-flight MALDI mass spectrometry of proteins above 25,000 Da. J. Mass. Spectrom. 32:1997;1111-1116.
3. Benard S., Arnhold J., Lehnert M., Schiller J., Arnold K. Experiments towards quantification of saturated and polyunsaturated diacylglycerols by matrix-assisted laser desorption and ionization time-of-flight mass spectrometry. Chem. Phys. Lipids. 100:1999;115-125.
4. Berridge M.J., Irvine R.F. Inositol trisphosphate, a novel second messenger in cellular signal transduction. Nature. 312:1984;315-321.
5. Braun S., Kalinowski H.-O., Berger S. 150 and More Basic NMR Experiments: A Practical Course. 1998;Wiley-VCH, Weinheim, New York, Chichester, Brisbane, Singapore, Toronto.
6. Carpenter C.L., Cantley L.C. Phosphoinositide kinases. Curr. Opin. Cell Biol. 8:1996;153-158.
7. Chen P., Baker A.G., Novotny M.V. The use of osazones as matrices for the matrix-assisted laser desorption/ionization mass spectrometry of carbohydrates. Anal. Biochem. 244:1997;144-151.
8. Divecha N., Irvine R.F. Phospholipid signaling. Cell. 80:1995;269-278.
9. Duckworth B.C., Cantley L.C. PI 3-kinase and receptor-linked signal transduction. Bell R.M., Exton J.H., Prescott S.M. Lipid Second Messengers. 1996;125-175 Plenum Press, New York.
10. Duncan M.W., Matanović G., Cerpa-Poljak A. Quantitative analysis of low molecular weight compounds of biological interest by matrix-assisted laser desorption ionization. Rapid Commun. Mass Spectrom. 7:1993;1090-1094.
11. Fitzgerald M.C., Parr G.R., Smith L.M. Basic matrices for the matrix-assisted laser desorption/ionization mass spectrometry of proteins and oligonucleotides. Anal. Chem. 65:1993;3204-3211.
12. 2). Biochim. Biophys. Acta. 979:1989;105-112.
13. Günther H. NMR-Spektroskopie. 1983;Thieme-Verlag, Stuttgart, New York.
14. Gunnarsson T., Ekblad L., Karlsson A., Michelsen P., Odham G., Jergil B. Separation of polyphosphoinositides using normal-phase high-performance liquid chromatography and evaporative light scattering detection or electrospray mass spectrometry. Anal. Biochem. 254:1997;293-296.
15. Harvey D.J. Matrix-assisted laser desorption/ionization mass spectrometry of phospholipids. J. Mass Spectrom. 30:1995;1333-1346.
16. Harvey D.J. Matrix-assisted laser desorption/ionization mass spectrometry of carbohydrates. Mass Spectrom. Rev. 18:1999;349-451.
17. Hillenkamp F., Karas M., Beavis R.C., Chait B.T. Matrix-assisted laser desorption/ionization mass spectrometry of biopolymers. Anal. Chem. 63:1991;1193A-1203A.
18. Hsu F.F., Turk J. Characterization of phosphatidylinositol, phosphatidylinositol-4-phosphate, and phosphatidylinositol-4,5-bisphosphate by electrospray ionization tandem mass spectrometry: a mechanistic study. J Am. Soc. Mass Spectrom. 11:2000;986-999.
19. Isenberg G. Actin-binding protein-lipid interactions. J. Muscle Res. Cell Motil. 12:1991;136-144.
20. Isenberg G., Niggli V. Interaction of cytoskeletal proteins with membrane lipids. Int. Rev. Cytol. 178:1998;73-125.
21. Janmey P.A. Cell membranes and the cytosceleton. Lipowsky R., Sackmann E. Handbook of Biological Physics, Structure and Dynamics of Membranes. 1:1995;805-849 Elsevier, Amsterdam.
22. Jensen N.J., Tomer K.B., Gross M.L. FAB MS/MS for phosphatidylinositol, -glycerol, -ethanolamine and other complex phospholipids. Lipids. 22:1987;480-489.
23. Jerlich A., Pitt A.R., Schaur R.J., Spickett C.M. Pathways of phospholipid oxidation by HOCl in human LDL detected by LC-MS. Free Radic. Biol. Med. 28:2000;673-682.
24. Kapeller R., Cantley L.C. Phosphatidylinositol 3-kinase. Bioessays. 16:1994;565-576.
25. Karas M., Glückmann M., Schäfer J. Ionization in matrix-assisted laser desorption/ionization: singly charged molecular ions are the lucky survivors. J. Mass Spectrom. 35:2000;1-12.
26. Kerwin J.L., Tuininga A.R., Eriksson L.H. Identification of molecular species of glycerophospholipids and sphingomyelin using electrospray mass spectrometry. J. Lipid Res. 35:1994;1102-1114.
27. Marto J.A., White F.M., Seldomridge S., Marshall A.G. Structural characterization of phospholipids by matrix-assisted laser desorption/ionization fourier transform ion cyclotron resonance mass spectrometry. Anal. Chem. 67:1995;3979-3984.
28. Michelsen P., Jergil B., Odham G. Quantification of polyphosphoinositides using selected-ion monitoring electrospray mass spectrometry. Rapid Commun. Mass Spectrom. 9:1995;1109-1114.
29. Petković, M., Schiller, J., Müller, M., Benard, S., Reichl, S., Arnold, K., Arnhold, J., 2001. Detection of individual phospholipids in lipid mixtures by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry: phosphatidylcholine prevents the detection of further species. Anal. Biochem. 289, 202-216.
30. Schiller J., Arnold K. Mass spectrometry in structural biology. Meyers R.A. Encyclopedia of Analytical Chemistry. 2000;559-585 John Wiley & Sons, Chichester.
31. Schiller J., Arnhold J., Benard S., Müller M., Reichl S., Arnold K. Lipid analysis by matrix-assisted laser desorption and ionization mass spectrometry: a methodological approach. Anal. Biochem. 267:1999a;46-56.
32. Schiller J., Arnhold J., Benard S., Reichl S., Arnold K. Cartilage degradation by hyaluronate lyase and chondoitin ABC lyase: a MALDI-TOF mass spectrometric study. Carbohydr. Res. 318:1999b;116-122.
33. Schiller J., Arnhold J., Glander H.-J., Arnold K. Lipid analysis of human spermatozoa and seminal plasma by MALDI-TOF mass spectrometry and NMR spectroscopy - effects of freezing and thawing. Chem. Phys. Lipids. 106:2000;145-156.
34. Sherman W.R., Ackermann K.E., Bateman R.H., Green B.N., Lewis I. Mass-analysed ion kinetic energy spectra and B1E-B2 triple sector mass spectrometric analysis of phosphoinositides by fast atom bombardment. Biomed. Mass. Spectrom. 12:1985;409-413.
35. Spickett C.M., Pitt A.R., Brown A.J. Direct observation of lipid hydroperoxides in phospholipid vesicles by electrospray mass spectrometry. Free Radic. Biol. Med. 25:1998;613-620.
36. Stahl B., Steup M., Karas M., Hillenkamp F. Analysis of neutral oligosaccharides by matrix-assisted laser desorption/ionization mass spectrometry. Anal. Chem. 63:1991;1463-1466.
37. Stoyanov B., Volinia S., Hanck T., Rubio I., Loubtchenkov M., Malek D., Stoyanova S., Vanhaesebroeck B., Dhand R., Nürnberg B., Gierschick P., Seedorf K., Hsuan J.J., Waterfield M.D., Wetzker R. Cloning and characterization of a G-protein-activated human phosphoinositide 3-kinase. Science. 269:1995;690-693.
38. Toner M., Vaio G., McLaughlin A., McLaughlin S. Adsorption of cations to phosphatidylinositol 4,5-bisphosphate. Biochemistry. 27:1988;7435-7443.
39. Wymann M.P., Bulgarelli-Leva G., Zvelebil M.J., Pirola L., Vanhaesebroeck B., Waterfield M.D., Panayotou G. Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction. Mol. Cell Biol. 16:1996;1722-1733.
40. Zenobi R., Knochenmuss R. Ion formation in MALDI mass spectrometry. Mass Spectrom. Rev. 17:1998;337-366.
41. Zvelebil M.J., MacDougall L., Leevers S., Volinia S., Vanhaesebroeck B., Gout I., Panayotou G., Domin J., Stein R., Pages F., Koga H., Salim K., Linacre J., Das P., Panaretou C., Wetzker R., Waterfield M. Structural and functional diversity of phosphoinositide 3-kinases. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 351:1996;217-223.