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Volumn 59, Issue 2, 2002, Pages 307-322

Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters

Author keywords

ABC transporters; Cancer cells; Flavonoids; Leishmania; Modulators; Multidrug resistance (MDR); P glycoprotein; Yeast

Indexed keywords

ABC TRANSPORTER; CYTOTOXIC AGENT; FLAVONOID; GLYCOPROTEIN P;

EID: 18244376403     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00018-002-8424-8     Document Type: Review
Times cited : (240)

References (128)
  • 15
    • 0032698874 scopus 로고    scopus 로고
    • ABC-ATPases, adaptable energy generators fuelling transmembrane movement of a variety of molecules in organisms from bacteria to humans
    • (1999) J. Mol. Biol. , vol.293 , pp. 381-399
    • Holland, I.B.1    Blight, M.A.2
  • 21
    • 0035937707 scopus 로고    scopus 로고
    • Correlation between steady-state ATP hydrolysis and vanadate-induced ADP trapping in human P-glycoprotein. Evidence for ADP release as the rate-limiting step in the catalytic cycle and its modulation by substrates
    • (2001) J. Biol. Chem. , vol.276 , pp. 8657-8664
    • Kerr, K.M.1    Sauna, Z.E.2    Ambudkar, S.V.3
  • 30
    • 0028307550 scopus 로고    scopus 로고
    • Phosphatidylcholine translocase: A physiological role for the mdr2 gene
    • Cell , vol.77 , pp. 1071-1081
    • Ruetz, S.1    Gros, P.2
  • 33
    • 0031434236 scopus 로고    scopus 로고
    • Identification of the drug-binding site of human P-glycoprotein using a thiol-reactive substrate
    • (1997) J. Biol. Chem. , vol.272 , pp. 31945-31948
    • Loo, T.W.1    Clarke, D.M.2
  • 34
    • 0030966409 scopus 로고    scopus 로고
    • Kinetics of the multidrug transporter (P-glycoprotein) and its reversal
    • (1997) Physiol. Rev. , vol.77 , pp. 545-590
    • Stein, W.D.1
  • 46
    • 0028111508 scopus 로고
    • Molecular cloning and expression of the Saccharomyces cerevisiae STS1 gene product. A yeast ABC transporter conferring mycotoxin resistance
    • (1994) J. Biol. Chem. , vol.269 , pp. 4180-4186
    • Bissinger, P.H.1    Kuchler, K.2
  • 51
  • 70
    • 0028028123 scopus 로고
    • The antiprogestatin drug RU486 potentiates doxorubicin cytotoxicity in multidrug resistant cells through inhibition of P-glycoprotein function
    • (1994) FEBS Lett. , vol.355 , pp. 187-191
    • Lecureur, V.1    Fardel, O.2    Guillouzo, A.3
  • 83
  • 120
    • 0029028792 scopus 로고
    • Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: Implications for drug delivery and activity in cancer chemotherapy
    • (1995) Mol. Carcinog. , vol.13 , pp. 129-134
    • Wacher, V.J.1    Wu, C.Y.2    Benet, L.Z.3
  • 122
    • 0033973926 scopus 로고    scopus 로고
    • Influence of dietary components on the gastrointestinal metabolism and transport of drugs
    • (2000) Ther. Drug. Monit. , vol.22 , pp. 131-136
    • Evans, A.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.