-
1
-
-
0025269612
-
Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum
-
Foote, S. J. et al. Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum. Nature 345, 255-258 (1990).
-
(1990)
Nature
, vol.345
, pp. 255-258
-
-
Foote, S.J.1
-
2
-
-
0024356582
-
Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum
-
Wilson, C. M. et al. Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum. Science 244, 1184-1186.
-
Science
, vol.244
, pp. 1184-1186
-
-
Wilson, C.M.1
-
3
-
-
0027474443
-
Derivation of highly mefloquine-resistant lines from Plasmodium falciparum in vitro
-
Peel, S. A., Merritt, S. C., Handy, J. & Baric, R. S. Derivation of highly mefloquine-resistant lines from Plasmodium falciparum in vitro. Am. J. Trop. Med. Hyg. 48, 385-397.
-
Am. J. Trop. Med. Hyg.
, vol.48
, pp. 385-397
-
-
Peel, S.A.1
Merritt, S.C.2
Handy, J.3
Baric, R.S.4
-
4
-
-
0028014644
-
Selection for mefloquine resistance in Plasmodium falciparum is linked to amplification of the pfmdr1 gene and cross-resistance to halofantrine and quinine
-
Cowman, A. F., Galatis, D. & Thompson, K. J. Selection for mefloquine resistance in Plasmodium falciparum is linked to amplification of the pfmdr1 gene and cross-resistance to halofantrine and quinine. Proc. Natl Acad. Sci, USA 91, 1143-1147 (1994).
-
(1994)
Proc. Natl Acad. Sci, USA
, vol.91
, pp. 1143-1147
-
-
Cowman, A.F.1
Galatis, D.2
Thompson, K.J.3
-
5
-
-
0028135205
-
A strong association between mefloquine and halofantrine resistance and amplification, overexpression, and mutation in the P-glycoprotein gene homolog (pfmdr) of Plasmodium falciparum in vitro
-
Peel, S. A., Bright, P., Yount, B., Handy, J. & Baric, R. S. A strong association between mefloquine and halofantrine resistance and amplification, overexpression, and mutation in the P-glycoprotein gene homolog (pfmdr) of Plasmodium falciparum in vitro. Am. J. Trop. Med. Hyg. 51, 648-658 (1994).
-
(1994)
Am. J. Trop. Med. Hyg.
, vol.51
, pp. 648-658
-
-
Peel, S.A.1
Bright, P.2
Yount, B.3
Handy, J.4
Baric, R.S.5
-
6
-
-
0025305350
-
Chloroquine resistance not linked to mdr-like genes in a Plasmodium falciparum cross
-
Wellems, T. E. et al. Chloroquine resistance not linked to mdr-like genes in a Plasmodium falciparum cross. Nature 345, 253-255. (1990).
-
(1990)
Nature
, vol.345
, pp. 253-255
-
-
Wellems, T.E.1
-
7
-
-
0024338609
-
Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum
-
Foote, S. J., Thompson, J. K., Cowman, A. F. & Kemp, D. J. Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum. Cell 57, 921-930 (1989).
-
(1989)
Cell
, vol.57
, pp. 921-930
-
-
Foote, S.J.1
Thompson, J.K.2
Cowman, A.F.3
Kemp, D.J.4
-
8
-
-
0032527779
-
Allelic exchange at the endogenous genomic locus in Plasmodium falciparum proves the role of dihydropteroate synthase in sulfadoxine-resistant malaria
-
Triglia, T., Wang, P., Sims, P. F. G., Hyde, J. E. & Cowman, A. F. Allelic exchange at the endogenous genomic locus in Plasmodium falciparum proves the role of dihydropteroate synthase in sulfadoxine-resistant malaria. EMBO J. 17, 3807-3815 (1998).
-
(1998)
EMBO J.
, vol.17
, pp. 3807-3815
-
-
Triglia, T.1
Wang, P.2
Sims, P.F.G.3
Hyde, J.E.4
Cowman, A.F.5
-
9
-
-
0025786518
-
A P-glycoprotein homologue of Plasmodium falciparum is localized on the digestive vacuole
-
Cowman, A. F., Karcz, S., Galatis, D & Culvenor, J. G. A P-glycoprotein homologue of Plasmodium falciparum is localized on the digestive vacuole. J. Cell Biol. 113, 1033-1042 (1991).
-
(1991)
J. Cell Biol.
, vol.113
, pp. 1033-1042
-
-
Cowman, A.F.1
Karcz, S.2
Galatis, D.3
Culvenor, J.G.4
-
10
-
-
0018606732
-
Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique
-
Desjardins, R. E., Canfield, C. J., Haynes, J. D. & Chulay, J. D. Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique. Antimicrob. Agents Chemother. 16, 710-718 (1979).
-
(1979)
Antimicrob. Agents Chemother.
, vol.16
, pp. 710-718
-
-
Desjardins, R.E.1
Canfield, C.J.2
Haynes, J.D.3
Chulay, J.D.4
-
11
-
-
0026450734
-
Susceptibility of African isolates of Plasmodium falciparum to artemisinin (gingluosu)
-
Doury, J. C., Ringwald, P., Gudain, J. & Le Bras, J. Susceptibility of African isolates of Plasmodium falciparum to artemisinin (gingluosu). Trop. Med. Parasitol. 43, 197-198 (1992).
-
(1992)
Trop. Med. Parasitol.
, vol.43
, pp. 197-198
-
-
Doury, J.C.1
Ringwald, P.2
Gudain, J.3
Le Bras, J.4
-
12
-
-
85046499191
-
Access to hematin: The basis of chloroquine resistance
-
Bray, P. G., Mungthin, M., Ridley, R. G. & Ward, S. A. Access to hematin: the basis of chloroquine resistance. Mol. Pharmacol. 34, 170-179 (1993).
-
(1993)
Mol. Pharmacol.
, vol.34
, pp. 170-179
-
-
Bray, P.G.1
Mungthin, M.2
Ridley, R.G.3
Ward, S.A.4
-
13
-
-
0030582428
-
The role of drug accumulation in 4-aminoquinoline antimaterial potency. The influence of structural substitution and physiochemical properties
-
Hawley, S. R., Bray, P. G., O'Neill, P. M., Park, B. K. & Ward, S. A. The role of drug accumulation in 4-aminoquinoline antimaterial potency. The influence of structural substitution and physiochemical properties. Biochem Pharmacol. 52, 723-733 (1996).
-
(1996)
Biochem Pharmacol.
, vol.52
, pp. 723-733
-
-
Hawley, S.R.1
Bray, P.G.2
O'Neill, P.M.3
Park, B.K.4
Ward, S.A.5
-
14
-
-
0023137728
-
Reversal of cloroquine resistance in Plasmodium falciparum by verapamil
-
Martin, S. K., Odunia, A. M. & Milhous, W. K. Reversal of cloroquine resistance in Plasmodium falciparum by verapamil Science 235, 899-901 (1987).
-
(1987)
Science
, vol.235
, pp. 899-901
-
-
Martin, S.K.1
Odunia, A.M.2
Milhous, W.K.3
-
15
-
-
0030451452
-
Physiochemical properties correlated with drug resistance and the reversal of drug resistance in Plasmodium falciparum
-
Bray, P. G., Hawley, S. R., Mungthin, M. & Ward, S. A. Physiochemical properties correlated with drug resistance and the reversal of drug resistance in Plasmodium falciparum. Mol. Pharmacol. 50, 1559-1566 (1996).
-
(1996)
Mol. Pharmacol.
, vol.50
, pp. 1559-1566
-
-
Bray, P.G.1
Hawley, S.R.2
Mungthin, M.3
Ward, S.A.4
-
16
-
-
0029062531
-
Current views on the mechanisms of resistance to quinoline-containing drugs in Plasmodium falciparum
-
Ward, S, A., Bray, P. G., Mungthin, M. & Hawley, S. R. Current views on the mechanisms of resistance to quinoline-containing drugs in Plasmodium falciparum. Ann. Trop. Med. Parasitol. 89, 121-124 (1995).
-
(1995)
Ann. Trop. Med. Parasitol.
, vol.89
, pp. 121-124
-
-
Ward, S.A.1
Bray, P.G.2
Mungthin, M.3
Hawley, S.R.4
-
17
-
-
0344867895
-
Cellular uptake of choroquine is dependent of binding to ferriprotoporphyrin IX and is independent of NHE activity in Plasmodium falciparum
-
Bray, P. G. et al. Cellular uptake of choroquine is dependent of binding to ferriprotoporphyrin IX and is independent of NHE activity in Plasmodium falciparum. J. Cell Biol. 145, 363-376 (1999).
-
(1999)
J. Cell Biol.
, vol.145
, pp. 363-376
-
-
Bray, P.G.1
-
18
-
-
0031589733
-
Complex polymorphisms in an ∼330 kDa protein are linked to choroquine-resistant P. falciparum in Southeast Asia and Africa
-
Su, X. -Z., Kirkman, L. A., Fujioka, H. & Wellems, T. E. Complex polymorphisms in an ∼330 kDa protein are linked to choroquine-resistant P. falciparum in Southeast Asia and Africa. Cell 91, 593-603 (1997).
-
(1997)
Cell
, vol.91
, pp. 593-603
-
-
Su, X.-Z.1
Kirkman, L.A.2
Fujioka, H.3
Wellems, T.E.4
-
19
-
-
0031452191
-
Stable transgene expression in Plasmodium falciparum
-
Crabb, B. S., Triglia, T., Waterkeym. J. G. & Cowman, A. F. Stable transgene expression in Plasmodium falciparum. Mol. Biochem. Parasitol, 90, 131-144 (1997).
-
(1997)
Mol. Biochem. Parasitol
, vol.90
, pp. 131-144
-
-
Crabb, B.S.1
Triglia, T.2
Waterkeym J, G.3
Cowman, A.F.4
-
20
-
-
0030035041
-
Transformation of Plasmodium falciparum malaria parasites by homologous integration of plasmids that confer resistance to pyrimethanmine
-
Wu, Y., Kirkman, L. A. & Wellems, T. E. Transformation of Plasmodium falciparum malaria parasites by homologous integration of plasmids that confer resistance to pyrimethanmine. Proc. Natl Acad. Sci. USA 93, 1130-1134 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 1130-1134
-
-
Wu, Y.1
Kirkman, L.A.2
Wellems, T.E.3
-
21
-
-
0030006717
-
Characterization of promoters and stable transfection by homologous and nonhomologous recombination in Plasmodium falciparum
-
Crabb, B. S. & Cowman, A. F. Characterization of promoters and stable transfection by homologous and nonhomologous recombination in Plasmodium falciparum. Proc. Natl Acad. Sci. USA 93, 7289-7294 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 7289-7294
-
-
Crabb, B.S.1
Cowman, A.F.2
-
22
-
-
0030904788
-
Targeted gene disruption shows that knobs enable malaria-infected red cells to cytoadhere under physiological shear stress
-
Crabb, B. S. et al. Targeted gene disruption shows that knobs enable malaria-infected red cells to cytoadhere under physiological shear stress. Cell 89, 287-296 (1997).
-
(1997)
Cell
, vol.89
, pp. 287-296
-
-
Crabb, B.S.1
-
23
-
-
0030885188
-
Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil
-
Fidock, D. A & Wellems, T. E. Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil. Proc. Natl Acad. Sci. USA 94, 10931-10936 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 10931-10936
-
-
Fidock, D.A.1
Wellems, T.E.2
-
24
-
-
0030176163
-
Plasmodium falciparum: Isolation of large numbers of parasite clones from infected blood samples
-
Kirkman, L. A., Su, X. Z. & Wellems, T. E. Plasmodium falciparum: isolation of large numbers of parasite clones from infected blood samples. Exp. Parasitol. 83, 143-149 (1996).
-
(1996)
Exp. Parasitol.
, vol.83
, pp. 143-149
-
-
Kirkman, L.A.1
Su, X.Z.2
Wellems, T.E.3
-
25
-
-
0030566669
-
In vitro selection of halofantrine resistance in Plasmodium falciparum is not associated with increased expression of Pgh1
-
Ritchie, G. Y. et al. In vitro selection of halofantrine resistance in Plasmodium falciparum is not associated with increased expression of Pgh1. Mol. Biochem. Parasitol. 83, 35-46 (1996).
-
(1996)
Mol. Biochem. Parasitol.
, vol.83
, pp. 35-46
-
-
Ritchie, G.Y.1
-
26
-
-
0025046280
-
Kinetic modelling of the response of Plasmodium falciparum to choloroquine and its experimental testing in vitro. Implications for mechanism of action and of resistance to the drug
-
Geary, T. G., Divo, A. D., Jensen, J. B., Zangwill, M. & Ginsburg, H. Kinetic modelling of the response of Plasmodium falciparum to choloroquine and its experimental testing in vitro. Implications for mechanism of action and of resistance to the drug. Biochem. Pharmacol. 40, 685-691 (1990).
-
(1990)
Biochem. Pharmacol.
, vol.40
, pp. 685-691
-
-
Geary, T.G.1
Divo, A.D.2
Jensen, J.B.3
Zangwill, M.4
Ginsburg, H.5
-
27
-
-
0029097044
-
Plasmodium falciparum: Detection of P-glycoprotein in chloroquine-susceptible and chloroquine-resistant clones and isolates
-
Cremer, G., Basco, L. K., Le Bras, J. L., Camus, D. & Slomianny, C. Plasmodium falciparum: detection of P-glycoprotein in chloroquine-susceptible and chloroquine-resistant clones and isolates. Exp. Parasitol. 81, 1-8 (1995).
-
(1995)
Exp. Parasitol.
, vol.81
, pp. 1-8
-
-
Cremer, G.1
Basco, L.K.2
Le Bras, J.L.3
Camus, D.4
Slomianny, C.5
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