Altered drug membrane permeability in a multidrug-resistant Leishmania tropica line

Biochemical Pharmacology

Volumn 55, Issue 2, 1998, Pages 131-139

  Chiquero, M Jesús ^a   Pérez Victoria, José M ^a   O'Valle, Francisco ^b   González Ros, José M ^c   Del Moral, Raimundo G ^b   Ferragut, José A ^c   Castanys, Santiago ^a   Gamarro, Francisco ^a  

^a INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

^b UNIVERSITY OF GRANADA   (Spain)

^c UNIVERSITY OF ALICANTE   (Spain)

Author keywords

Altered permeability; Leishmania tropica; MDR phenotype; Resistance to daunomycin

Indexed keywords

DAUNORUBICIN; DOXORUBICIN; GLYCOPROTEIN P; VINBLASTINE;

ARTICLE; DRUG UPTAKE; FLOW CYTOMETRY; LEISHMANIA TROPICA; MEMBRANE PERMEABILITY; MULTIDRUG RESISTANCE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; DAUNORUBICIN; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; KINETICS; LEISHMANIA TROPICA; P-GLYCOPROTEIN; PHENOTYPE; PUROMYCIN; VINBLASTINE;

EID: 0344333486     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(97)00385-7     Document Type: Article

References (42)

1. Simon SM, Schindler M. Cell biological mechanisms of multidrug resistance in tumors. Proc Natl Acad Sci USA. 91:1994;3497-3504.
2. Endicott JA, Ling V. The biochemistry of P-glycoprotein-mediated multidrug resistance. Annu Rev Biochem. 58:1989;137-171.
3. +-ATPase subunit C is overexpressed in multidrug-resistant HL60 cells. Biochem Biophys Res Commun. 182:1992;675-681.
4. Boscoboinik D, Gupta RS, Epand RM. Investigation of the relationship between altered intracellular pH and multidrug resistance in mammalian cells. Br J Cancer. 61:1990;568-572.
5. Eytan GD, Regev R, Oren G, Assaraf YG. The role of passive transbilayer drug movement in multidrug resistance and its modulation. J Biol Chem. 271:1996;12897-12902.
6. Soto F, Canaves JM, Gonzalez-Ros JM, Ferragut JA. Rapid kinetics of the interaction between daunomycin and drug-sensitive or drug-resistant P388 leukemia cells. FEBS Lett. 301:1992;119-123.
7. Ellenberger TE, Beverley SM. Biochemistry and regulation of folate and methotrexate transport in Leishmania major. J Biol Chem. 262:1987;10053-10058.
8. Kaur K, Coons T, Emmett K, Ullman B. Methotrexate-resistant Leishmania donovani genetically deficient in the folate-methotrexate transporter. J Biol Chem. 263:1988;7020-7028.
9. Beverley SM. Gene amplification in Leishmania. Annu Rev Microbiol. 45:1991;417-444.
10. Ouellette M, Papadopoulou B. Mechanisms of drug resistance in Leishmania. Parasitol Today. 9:1993;150-153.
11. Wilson CM, Serrano AE, Wasley A, Bogenschutz MP, Shankar AH, Wirth DF. Amplification of a gene related to mammalian mdr genes in drug resistant Plasmodium falciparum. Science. 244:1989;1184-1186.
12. Samuelson J, Ayala P, Orozco E, Wirth D. Emetine-resistant mutants of Entamoeba histolytica overexpress mRNAs for multidrug resistance. Mol Biochem Parasitol. 38:1990;281-290.
13. Henderson DM, Sifri CD, Rodgers M, Wirth DF, Hendrickson N, Ullman B. Multidrug resistance in Leishmania donovani is conferred by amplification of a gene homologous to the mammalian mdr1 gene. Mol Cell Biol. 12:1992;2855-2865.
14. Chow LMC, Wong AKC, Ullman B, Wirth DF. Cloning and functional analysis of an extrachromosomally amplified multidrug resistance-like gene in Leishmania enriettii. Mol Biochem Parasitol. 60:1993;195-208.
15. Iovannisci DM, Ullman B. High efficiency plating method for Leishmania promastigotes in semi-defined or completely-defined medium. J Parasitol. 69:1983;633-636.
16. Jackson PR, Lawrie JM, Stiteler JM, Hawkins DW, Wohlhieter JA, Rowtin ED. Detection and characterization of Leishmania species and strains from mammals and vectors by hybridization and restriction endonuclease digestion of kinetoplast DNA. Veter Parasitol. 20:1986;195-215.
17. Gamarro F, Chiquero MJ, Amador MV, Légaré D, Ouellette M, Castanys S. P-glycoprotein overexpression in methotrexate-resistant Leishmania tropica. Biochem Pharmacol. 47:1994;1939-1947.
18. Ellenberger TE, Beverley SM. Multidrug resistance and conservative amplification of the H region in Leishmania major. J Biol Chem. 264:1989;15094-15103.
19. Robinson JP. Handbook of Flow Cytometry Methods. 1993;Willey-Liss, New York.
20. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 162:1987;156-159.
21. Sambrook J, Fristch EF and Maniatis T, Eds. Molecular Cloning - A Laboratory Manual, 2nd Ed. Cold Spring Harbor Laboratory Press, Plainview, New York, 1989.
22. Gueiros-Filho FG, Gomez FCA, Araripe JR, Lopez UG. Characterization of multiple drug resistance genes in Leishmania amazonensis. Memorias do Instituto Oswaldo Cruz. 87:1992;42-43.
23. Chu G, Vollrath D, Davis RW. Separation of large DNA molecules by contour-clamped homogeneous electric field. Science. 234:1986;1582-1585.
24. Birnboim HC. A rapid alkaline extraction method for the isolation of plasmid DNA. Methods Enzymol. 100:1983;243-255.
25. 2-terminal domain. J Cell Biol. 128:1995;499-508.
26. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the folin phenol reagent. J Biol Chem. 193:1951;265-275.
27. Sanchez A, Castanys S, Gamarro F. Increased P-type ATPase activity in Leishmania tropica resistant to methotrexate. Biochem Biophys Res Commun. 199:1994;855-861.
28. Herzog CE, Tsokos M, Bates SE, Fojo AT. Increased mdr-1/P-glycoprotein expression after treatment of human colon carcinoma cells with P-glycoprotein antagonists. J Biol Chem. 268:1993;2946-2952.
29. Fojo A, Akiyama SI, Gottesman MM, Pastan I. Reduced drug accumulation in multiply drug-resistant human KB carcinoma cell lines. Cancer Res. 45:1985;3002-3007.
30. Choi K, Chen C, Kriegler M, Roninson IB. An altered pattern of cross-resistance in multidrug-resistant human cells results from spontaneous mutations in the mdr1. (P-glycoprotein) gene. Cell. 53:1988;519-529.
31. Burke TG, Tritton TR. Structural basis of anthracycline selectivity for unilamellar phosphatidylcholine vesicles an equilibrium binding study . Biochemistry. 24:1985;1768-1776.
32. Tritton TR and Posada JA, The role of the cell surface membrane in adriamycin resistance. In: Resistance to Antineoplastic Drugs (ed. Kessel D) pp. 127-137, 1989, CRC Press Inc, Boca Raton, Florida.
33. Mankhetkorn S, Dubru F, Hesschenbrouck J, Fiallo M, Garnier-Suillerot A. Relation among the resistance factor, kinetics of update, and kinetics of the P-glycoprotein-mediated efflux of doxorubicin, daunorubicin, 8-(S)-fluoroidarubicin, and idarubicin in multidrug-resistant K562 cells. Mol Pharmacol. 49:1996;532-539.
34. Skovsgaard T. Mechanisms of resistance to daunorubicin in Ehrlich ascites tumor cells. Cancer Res. 38:1978;1785-1791.
35. Versantvoort CHM, Broxterman HJ, Pinedo HM, de Vries EGE, Feller N, Kuiper CM, Lankelma J. Energy-dependent processes involved in reduced drug accumulation in multidrug-resistant human lung cancer cell lines without P-glycoprotein expression. Cancer Res. 52:1992;17-23.
36. Simon SM, Schindler M. Cell biological mechanisms of multidrug resistance in tumors. Proc Natl Acad Sci USA. 91:1994;3497-3504.
37. Turco SJ, Descoteaux A. The lipophosphoglycan of Leishmania parasites. Annu Rev Microbiol. 46:1992;65-94.
38. Siegfried JA, Burke TG, Tritton TR. Cellular transport of anthracyclines by passive diffusion. Biochem Pharmacol. 34:1985;593-598.
39. Higgins CF, Gottesman MM. Is the multidrug transporter a flippase? Trends Biochem Sci. 17:1992;18-21.
40. Gottesman MM, Pastan I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem. 62:1993;385-427.
41. Ramu A, Glaubiger D, Weintraub H. Differences in lipid composition of doxorubicin-sensitive and -resistant P388 cells. Cancer Treat Rep. 68:1984;637-641.
42. Escriba PV, Ferrer-Montiel AV, Ferragut JA, Gonzalez-Ros JM. Role of membrane lipids in the interaction of daunomycin with plasma membranes from tumor cells implications in drug-resistance phenomena . Biochemistry. 29:1990;7275-7282.