-
1
-
-
0029896163
-
Regulation, substrates and functions of Src
-
Brown, M. T. & Cooper, J. A. Regulation, substrates and functions of Src. Biochim. Biophys. Acta 1287, 121-149 (1996).
-
(1996)
Biochim. Biophys. Acta
, vol.1287
, pp. 121-149
-
-
Brown, M.T.1
Cooper, J.A.2
-
2
-
-
0023352242
-
Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cells
-
Quintrell, N. et al. Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cells. Mol. Cell. Biol. 7, 2267-2275 (1987).
-
(1987)
Mol. Cell. Biol.
, vol.7
, pp. 2267-2275
-
-
Quintrell, N.1
-
3
-
-
0023358725
-
Novel protein-tyrosine kinase gene (hck) preferentially expressed in cells of hematopoietic origin
-
Zeigler, S. F., March, J. D., Lewis, D. B. & Perlmutter, R. M. Novel protein-tyrosine kinase gene (hck) preferentially expressed in cells of hematopoietic origin. Mol. Cell. Biol. 7, 2276-2285 (1987).
-
(1987)
Mol. Cell. Biol.
, vol.7
, pp. 2276-2285
-
-
Zeigler, S.F.1
March, J.D.2
Lewis, D.B.3
Perlmutter, R.M.4
-
4
-
-
0028293147
-
Functional overlap in the src gene family: Interaction of hck and fgr impairs natural immunity
-
Lowell, C. A., Soriano, P. & Varmus, H. E. Functional overlap in the src gene family: interaction of hck and fgr impairs natural immunity. Genes Dev. 8, 387-398 (1994).
-
(1994)
Genes Dev.
, vol.8
, pp. 387-398
-
-
Lowell, C.A.1
Soriano, P.2
Varmus, H.E.3
-
5
-
-
0030067201
-
Deficiency of the Hck and Sre Tyrosine Kinases results in extreme levels of extramedullary hematopoiesis
-
Lowell, C. A., Niwa, M., Soriano, P. & Varmus, H. E. Deficiency of the Hck and Sre Tyrosine Kinases results in extreme levels of extramedullary hematopoiesis. Blood 87, 1780-1792 (1996).
-
(1996)
Blood
, vol.87
, pp. 1780-1792
-
-
Lowell, C.A.1
Niwa, M.2
Soriano, P.3
Varmus, H.E.4
-
6
-
-
0028859279
-
Protein modules and signalling networks
-
Pawson, R. Protein modules and signalling networks. Nature 373, 573-580 (1995).
-
(1995)
Nature
, vol.373
, pp. 573-580
-
-
Pawson, R.1
-
7
-
-
0028895654
-
Modular binding domains in signal transduction proteins
-
Cohen, G. B., Ren, R. & Baltimore, D. Modular binding domains in signal transduction proteins. Cell 80, 237-248 (1995).
-
(1995)
Cell
, vol.80
, pp. 237-248
-
-
Cohen, G.B.1
Ren, R.2
Baltimore, D.3
-
9
-
-
0026727936
-
Synthesis and biological evaluation of a series of flavones designed as inhibitors of protein tyrosine kinases
-
Cunningham, B. D., Threadgill, M. A., Groundwater, P. W., Dale, I. L. & Hickman, J. A. Synthesis and biological evaluation of a series of flavones designed as inhibitors of protein tyrosine kinases. Anti-cancer Drug Design 7, 365-384 (1992).
-
(1992)
Anti-cancer Drug Design
, vol.7
, pp. 365-384
-
-
Cunningham, B.D.1
Threadgill, M.A.2
Groundwater, P.W.3
Dale, I.L.4
Hickman, J.A.5
-
10
-
-
0026698924
-
Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides
-
Waksman, F. et al. Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides. Nature 358, 646-653 (1992).
-
(1992)
Nature
, vol.358
, pp. 646-653
-
-
Waksman, F.1
-
11
-
-
0026437577
-
Crystal structure of a Src-homology 3 (SH3) domain
-
Musacchio, A., Noble, M., Pauptit, R., Wierenga, R. & Saraste, M. Crystal structure of a Src-homology 3 (SH3) domain. Nature 359, 851-855 (1992).
-
(1992)
Nature
, vol.359
, pp. 851-855
-
-
Musacchio, A.1
Noble, M.2
Pauptit, R.3
Wierenga, R.4
Saraste, M.5
-
12
-
-
0026342401
-
Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase
-
Knichton, D. R. et al. Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase. Science 253, 407-414 (1991).
-
(1991)
Science
, vol.253
, pp. 407-414
-
-
Knichton, D.R.1
-
13
-
-
0028582185
-
Crystal structure of the tyrosine kinase domain of the human insulin receptor
-
Hubbard, S. R., Wei, L., Ellis, L. & Hendrickson, W. A. Crystal structure of the tyrosine kinase domain of the human insulin receptor. Nature 372, 746-754 (1994).
-
(1994)
Nature
, vol.372
, pp. 746-754
-
-
Hubbard, S.R.1
Wei, L.2
Ellis, L.3
Hendrickson, W.A.4
-
14
-
-
16144364951
-
Structural basis for activation of the human lymphocyte kinase Lck upon tyrosine phosphorylation
-
Yamaguchi, H. & Hendrickson, W. A. Structural basis for activation of the human lymphocyte kinase Lck upon tyrosine phosphorylation. Nature 384, 484-489 (1996).
-
(1996)
Nature
, vol.384
, pp. 484-489
-
-
Yamaguchi, H.1
Hendrickson, W.A.2
-
15
-
-
0029993727
-
Active and inactive protein kinases: Structural basis for regulation
-
Johnson, L. N., Noble, M. E. M. & Owen, D. J. Active and inactive protein kinases: structural basis for regulation. Cell 85, 149-158 (1996).
-
(1996)
Cell
, vol.85
, pp. 149-158
-
-
Johnson, L.N.1
Noble, M.E.M.2
Owen, D.J.3
-
16
-
-
0027474991
-
Left-handed polyproline II helices commonly occur in globular proteins
-
Adzhubei, A. A. & Sternberg, M. J. E. Left-handed polyproline II helices commonly occur in globular proteins. J. Mol. Biol. 229, 472-493 (1993).
-
(1993)
J. Mol. Biol.
, vol.229
, pp. 472-493
-
-
Adzhubei, A.A.1
Sternberg, M.J.E.2
-
17
-
-
0013484134
-
Structural basis for the binding of proline-rich peptides to SH3 domains
-
Yu, H., Chen, J. K., Feng, S., Dalgarno, D. C., Brauer, A. W. & Schreiber, S. L. Structural basis for the binding of proline-rich peptides to SH3 domains. Cell 76, 933-945 (1994).
-
(1994)
Cell
, vol.76
, pp. 933-945
-
-
Yu, H.1
Chen, J.K.2
Feng, S.3
Dalgarno, D.C.4
Brauer, A.W.5
Schreiber, S.L.6
-
18
-
-
0028485085
-
High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides
-
Musacchio, A., Saraste, M. & Wilmanns, M. High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides. Nature Struct. Biol. 1, 546-551 (1994).
-
(1994)
Nature Struct. Biol.
, vol.1
, pp. 546-551
-
-
Musacchio, A.1
Saraste, M.2
Wilmanns, M.3
-
19
-
-
0028337397
-
Crystal structure of the regulatory domains of the Src-family tyrosine kinase lck
-
Eck, M. J., Atwell, S. K., Shoelson, S. E. & Harrison, S. C. Crystal structure of the regulatory domains of the Src-family tyrosine kinase lck. Nature 368, 764-769 (1994).
-
(1994)
Nature
, vol.368
, pp. 764-769
-
-
Eck, M.J.1
Atwell, S.K.2
Shoelson, S.E.3
Harrison, S.C.4
-
20
-
-
0000127673
-
Å refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MnATP and a peptide inhibitor
-
Zheng, J. et al. 2.2 Å refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MnATP and a peptide inhibitor. Acta Crystallogr. D49, 362-365 (1993).
-
(1993)
Acta Crystallogr.
, vol.D49
, pp. 362-365
-
-
Zheng, J.1
-
21
-
-
0027182223
-
Crystal structure of cyclin-dependent kinase 2
-
DeBondt, H. L. et al. Crystal structure of cyclin-dependent kinase 2. Nature 363, 595-602 (1993).
-
(1993)
Nature
, vol.363
, pp. 595-602
-
-
DeBondt, H.L.1
-
22
-
-
0027409064
-
Binding of a high affinity phosphotyrosyl peptide to the src SH2 domain: Crystal structures of the complexed and peptide-free forms
-
Waksman, G., Shoelson, S. E., Plant, N., Cowburn, D. & Kuriyan, J. Binding of a high affinity phosphotyrosyl peptide to the src SH2 domain: crystal structures of the complexed and peptide-free forms. Cell 72, 779-790 (1993).
-
(1993)
Cell
, vol.72
, pp. 779-790
-
-
Waksman, G.1
Shoelson, S.E.2
Plant, N.3
Cowburn, D.4
Kuriyan, J.5
-
23
-
-
0027502504
-
Recognition of a high affinity phosphotyrosyl peptide by the Src homology 2 domain of p56lck
-
Eck, M. J., Shoelson, S. E. & Harrison, S. C. Recognition of a high affinity phosphotyrosyl peptide by the Src homology 2 domain of p56lck. Nature 362, 87-91 (1993).
-
(1993)
Nature
, vol.362
, pp. 87-91
-
-
Eck, M.J.1
Shoelson, S.E.2
Harrison, S.C.3
-
24
-
-
0027403027
-
SH2 domains recognize specific phosphopeptide sequences
-
Songyang, Z. et al. SH2 domains recognize specific phosphopeptide sequences. Cell 72, 767-778 (1993).
-
(1993)
Cell
, vol.72
, pp. 767-778
-
-
Songyang, Z.1
-
25
-
-
0028905264
-
Measurement of the binding tyrosyl phosphopeptides to SH2 domains: A reappraisal
-
Ladbury, J. E. et al. Measurement of the binding tyrosyl phosphopeptides to SH2 domains: a reappraisal. Proc. Natl Acad. Sci. USA 92, 3199-3203 (1995).
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 3199-3203
-
-
Ladbury, J.E.1
-
26
-
-
0028148629
-
Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains
-
Lim, W. A., Richards, D. M. & Fox, R. O. Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains. Nature 372, 375-379 (1994).
-
(1994)
Nature
, vol.372
, pp. 375-379
-
-
Lim, W.A.1
Richards, D.M.2
Fox, R.O.3
-
27
-
-
0028805516
-
A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein
-
Lee, C.-H. et al. A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein. EMBO J. 14, 5006-5015 (1995).
-
(1995)
EMBO J.
, vol.14
, pp. 5006-5015
-
-
Lee, C.-H.1
-
28
-
-
0343494918
-
Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain
-
Lee, C.-H., Saksela, K., Mirza, U. A., Chait, B. T. & Kuriyan, J. Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain. Cell 85, 931-942 (1996).
-
(1996)
Cell
, vol.85
, pp. 931-942
-
-
Lee, C.-H.1
Saksela, K.2
Mirza, U.A.3
Chait, B.T.4
Kuriyan, J.5
-
29
-
-
0028941630
-
Mutational analysis of the Src SH3 domain: The same residues of the ligand binding surface are important for intra- and inter-molecular interactions
-
Erpel, T. A., Superti-Furga, G. & Courtneidge, S. A. Mutational analysis of the Src SH3 domain: the same residues of the ligand binding surface are important for intra- and inter-molecular interactions. EMBO J. 14, 963-975 (1995).
-
(1995)
EMBO J.
, vol.14
, pp. 963-975
-
-
Erpel, T.A.1
Superti-Furga, G.2
Courtneidge, S.A.3
-
30
-
-
0024348319
-
Structural differences between repressed and derepressed forms of p60c-src
-
MacAuley, A. & Cooper, J. A. Structural differences between repressed and derepressed forms of p60c-src. Mol. Cell. Biol. 9, 2448-2656 (1989).
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 2448-2656
-
-
MacAuley, A.1
Cooper, J.A.2
-
31
-
-
0029029617
-
Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex
-
Juffrey, P. D. et al. Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex. Nature 376, 294-295 (1995).
-
(1995)
Nature
, vol.376
, pp. 294-295
-
-
Juffrey, P.D.1
-
32
-
-
0022081671
-
Activation of the pp60c-src kinase by middle T antigen binding or by dephosphorylation
-
Courtneidge, S. A. Activation of the pp60c-src kinase by middle T antigen binding or by dephosphorylation. EMBO J. 4, 1471-1477 (1985).
-
(1985)
EMBO J.
, vol.4
, pp. 1471-1477
-
-
Courtneidge, S.A.1
-
33
-
-
0023649672
-
Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation
-
Kmiecik, T. E. & Shalloway, D. Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation. Cell 49, 65-73 (1987).
-
(1987)
Cell
, vol.49
, pp. 65-73
-
-
Kmiecik, T.E.1
Shalloway, D.2
-
34
-
-
0023649622
-
Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-Src
-
Piwnica-Worms, H., Saunders, K. B., Roberts, T. M., Smith, A. E. & Cheng, S. H. Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-Src. Cell 49, 75-82 (1987).
-
(1987)
Cell
, vol.49
, pp. 75-82
-
-
Piwnica-Worms, H.1
Saunders, K.B.2
Roberts, T.M.3
Smith, A.E.4
Cheng, S.H.5
-
35
-
-
0023649625
-
Cell transformation by pp60c-Src mutated in the carboxy-terminal regulatory domain
-
Cartwright, C. A., Eckhart, W., Simon, S. & Kaplan, P. L. Cell transformation by pp60c-Src mutated in the carboxy-terminal regulatory domain. Cell 49, 83-91 (1987).
-
(1987)
Cell
, vol.49
, pp. 83-91
-
-
Cartwright, C.A.1
Eckhart, W.2
Simon, S.3
Kaplan, P.L.4
-
36
-
-
0022982097
-
Dephosphorylation or antibody binding to the carboxy terminus stimulates pp60c-src
-
Cooper, J. A. & King, C. S. Dephosphorylation or antibody binding to the carboxy terminus stimulates pp60c-src. Mol. Cell. Biol. 6, 4467-4477 (1986).
-
(1986)
Mol. Cell. Biol.
, vol.6
, pp. 4467-4477
-
-
Cooper, J.A.1
King, C.S.2
-
37
-
-
0024821548
-
Genetics of src. structure and functal organization of a protein tyrosine kinase
-
Parsons, T. J. & Weber, M. J. Genetics of src. structure and functal organization of a protein tyrosine kinase. Curr. Top. Microb. Immunol. 147, 80-127 (1989).
-
(1989)
Curr. Top. Microb. Immunol.
, vol.147
, pp. 80-127
-
-
Parsons, T.J.1
Weber, M.J.2
-
38
-
-
0031017838
-
Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement
-
Moarefi, I. et al. Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement. Nature 385, 650-653 (1997).
-
(1997)
Nature
, vol.385
, pp. 650-653
-
-
Moarefi, I.1
-
39
-
-
0029024880
-
The Ras GTPase-activating protein (GAP) is an SH3 domain-binding protein and substrate for the Src-related tyrosine kinase
-
Briggs, S. D., Bryant, S. S., Jove, R., Sanderson, S. D. & Smithgall, T. E. The Ras GTPase-activating protein (GAP) is an SH3 domain-binding protein and substrate for the Src-related tyrosine kinase, Hek. J. Biol. Chem. 270, 14718-14724 (1995).
-
(1995)
Hek. J. Biol. Chem.
, vol.270
, pp. 14718-14724
-
-
Briggs, S.D.1
Bryant, S.S.2
Jove, R.3
Sanderson, S.D.4
Smithgall, T.E.5
-
40
-
-
0029766101
-
Coordinate activation of c-Src by SH3- and SH2-binding sites on a novel p130Cas-related protein, Sin
-
Alexandropoulos, K. & Baltimore, D. Coordinate activation of c-Src by SH3- and SH2-binding sites on a novel p130Cas-related protein, Sin. Genes Dev. 10, 1341-1355 (1996).
-
(1996)
Genes Dev.
, vol.10
, pp. 1341-1355
-
-
Alexandropoulos, K.1
Baltimore, D.2
-
42
-
-
84889120137
-
Improved methods for building protein models in electron density maps and the location of errors in these models
-
Jones, T. A., Zou, J. Y., Cowan, S. W. & Kjeldgaard, M. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr. A47, 110-119 (1991).
-
(1991)
Acta Crystallogr.
, vol.A47
, pp. 110-119
-
-
Jones, T.A.1
Zou, J.Y.2
Cowan, S.W.3
Kjeldgaard, M.4
-
43
-
-
0004283184
-
-
Yale University, New Haven, CT
-
Brunger, A. R. X-PLOR (Yale University, New Haven, CT, 1992).
-
(1992)
X-PLOR
-
-
Brunger, A.R.1
-
45
-
-
0026319199
-
Protein folding and association: Insights from the interracial and thermodynamic properties of hydrocarbons
-
Nicholls, A., Sharp, K. A. & Honig, B. Protein folding and association: insights from the interracial and thermodynamic properties of hydrocarbons. Proteins Struct. Funct. Genet. 11, 281-296 (1991).
-
(1991)
Proteins Struct. Funct. Genet.
, vol.11
, pp. 281-296
-
-
Nicholls, A.1
Sharp, K.A.2
Honig, B.3
-
46
-
-
0024279342
-
Crystallographic refinement by simulated annealing: Application to a 2.8 Å resolution structure of aspartate aminotransferase
-
Brünger, A. T. Crystallographic refinement by simulated annealing: application to a 2.8 Å resolution structure of aspartate aminotransferase. J. Mol. Biol. 203, 803-816 (1988).
-
(1988)
J. Mol. Biol.
, vol.203
, pp. 803-816
-
-
Brünger, A.T.1
|