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1
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12144265945
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Sex Differences in the Myocardial Inflammatory Response to Ischemia/Reperfusion Injury
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Wang M, L Baker, BM Tsai, KK Meldrum, and DR Meldrum: Sex Differences in the Myocardial Inflammatory Response to Ischemia/Reperfusion Injury. Am J Physiol Endocrinol Metab 288, E321-E326 (2005)
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(2005)
Am J Physiol Endocrinol Metab
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Wang, M.1
Baker, L.2
Tsai, B.M.3
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Meldrum, D.R.5
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2
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11144341920
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The Role of Endogenous Testosterone in Myocardial Proinflammatory and Proapoptotic Signaling after Acute Ischemia-Reperfusion
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Wang M, BM Tsai, A Kher, LB Baker, GM Wairiuko, and DR Meldrum: The Role of Endogenous Testosterone in Myocardial Proinflammatory and Proapoptotic Signaling after Acute Ischemia-Reperfusion. Am J Physiol Heart Circ Physiol 288, H221-H226 (2005)
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(2005)
Am J Physiol Heart Circ Physiol
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Wang, M.1
Tsai, B.M.2
Kher, A.3
Baker, L.B.4
Wairiuko, G.M.5
Meldrum, D.R.6
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4
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0033542402
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The protective effects of estrogen on the cardiovascular system
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Mendelsohn ME and RH Karas: The protective effects of estrogen on the cardiovascular system. N Engl J Med 340, 1801-1811 (1999)
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N Engl J Med
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Mendelsohn, M.E.1
Karas, R.H.2
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5
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0031918203
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Tumor necrosis factor in the heart
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Meldrum DR: Tumor necrosis factor in the heart. Am J Physiol 274, R577-595 (1998)
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(1998)
Am J Physiol
, vol.274
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Meldrum, D.R.1
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6
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0036905303
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Vascular endothelial growth factor, polycystic ovary syndrome, and ovarian hyperstimulation syndrome
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Meldrum DR: Vascular endothelial growth factor, polycystic ovary syndrome, and ovarian hyperstimulation syndrome. Fertil Steril 78, 1170-1171 (2002)
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Fertil Steril
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Meldrum, D.R.1
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7
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0026770229
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Energetics of defective macrophage antigen presentation following hemorrhage
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Meldrum DR, A Ayala, and IH Chaudry: Energetics of defective macrophage antigen presentation following hemorrhage. Surgery 112, 150-158 (1992)
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(1992)
Surgery
, vol.112
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Meldrum, D.R.1
Ayala, A.2
Chaudry, I.H.3
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8
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0027185290
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Mechanism of diltiazem's immunomodulatory effects following hemorrhage and resuscitation
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Meldrum DR, A Ayala, and IH Chaudry: Mechanism of diltiazem's immunomodulatory effects following hemorrhage and resuscitation. Am J Physiol 265, C412-C421 (1993)
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(1993)
Am J Physiol
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Meldrum, D.R.1
Ayala, A.2
Chaudry, I.H.3
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10
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0026046587
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Diltiazem restores IL-2, IL-3, IL-6, and IFN-gamma synthesis and decreases host susceptibility to sepsis following hemorrhage
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Meldrum DR, A Ayala, MM Perrin, W Ertel, and IH Chaudry: Diltiazem restores IL-2, IL-3, IL-6, and IFN-gamma synthesis and decreases host susceptibility to sepsis following hemorrhage. J Surg Res 51, 158-164 (1991)
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(1991)
J Surg Res
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Meldrum, D.R.1
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Perrin, M.M.3
Ertel, W.4
Chaudry, I.H.5
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11
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0026080125
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Association between decreased splenic ATP levels and immunodepression: Amelioration with ATP-MgC12
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Meldrum DR, A Ayala, P Wang, W Ertel, and IH Chaudry: Association between decreased splenic ATP levels and immunodepression: amelioration with ATP-MgC12. Am J Physiol 261, R351-357 (1991)
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(1991)
Am J Physiol
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Meldrum, D.R.1
Ayala, A.2
Wang, P.3
Ertel, W.4
Chaudry, I.H.5
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12
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0030816872
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Adenosine decreases post-ischaemic cardiac TNF-alpha production: Anti-inflammatory implications for preconditioning and transplantation
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Meldrum DR, BS Cain, JC Cleveland, Jr., X Meng, A Ayala, A Banerjee, and AH Harken: Adenosine decreases post-ischaemic cardiac TNF-alpha production: anti-inflammatory implications for preconditioning and transplantation. Immunology 92, 472-477 (1997)
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(1997)
Immunology
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Meldrum, D.R.1
Cain, B.S.2
Cleveland Jr., J.C.3
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Ayala, A.5
Banerjee, A.6
Harken, A.H.7
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13
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0031000630
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1-adrenoceptor mediated, protein synthesis independent mechanism
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1-adrenoceptor mediated, protein synthesis independent mechanism. Am J Physiol 272, R718-R725 (1997)
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(1997)
Am J Physiol
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Meldrum, D.R.1
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Harken, A.H.6
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14
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0030253339
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Constructive priming of myocardium against ischemia-reperfusion injury
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Meldrum DR, JC Cleveland, MB Mitchell, RT Rowland, A Banerjee, and AH Harken: Constructive priming of myocardium against ischemia-reperfusion injury. Shock 6, 238-242 (1996)
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(1996)
Shock
, vol.6
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Meldrum, D.R.1
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Rowland, R.T.4
Banerjee, A.5
Harken, A.H.6
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16
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0031446179
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Adaptive and maladaptive mechanisms of cellular priming
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Meldrum DR, JC Cleveland, EE Moore, DA Partrick, A Banerjee, and AH Harken: Adaptive and maladaptive mechanisms of cellular priming. Ann Surg 226, 587-598. (1997)
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(1997)
Ann Surg
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Meldrum, D.R.1
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Partrick, D.A.4
Banerjee, A.5
Harken, A.H.6
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17
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0030200075
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Calcium induced inotropy is in part mediated by protein kinase C
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Meldrum DR, JC Cleveland, RT Rowland, A Banerjee, and AH Harken: Calcium induced inotropy is in part mediated by protein kinase C. J Surg Res 63, 400-405 (1996)
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(1996)
J Surg Res
, vol.63
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Meldrum, D.R.1
Cleveland, J.C.2
Rowland, R.T.3
Banerjee, A.4
Harken, A.H.5
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18
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0030846256
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Early and delayed preconditioning: Differential mechanisms and additive protection
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Meldrum DR, JC Cleveland, RT Rowland, A Banerjee, AH Harken, and X Meng: Early and delayed preconditioning: Differential mechanisms and additive protection. Am J Physiol 273, H725-H733 (1997)
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(1997)
Am J Physiol
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Meldrum, D.R.1
Cleveland, J.C.2
Rowland, R.T.3
Banerjee, A.4
Harken, A.H.5
Meng, X.6
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19
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0031127633
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Protein kinase C isoform diversity in preconditioning
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Meldrum DR, JC Cleveland, BC Sheridan, X Meng, F Robertson, BS Cain, AH Harken, and A Banerjee: Protein kinase C isoform diversity in preconditioning. J Surg Res 69, 183-187 (1997)
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(1997)
J Surg Res
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Meldrum, D.R.1
Cleveland, J.C.2
Sheridan, B.C.3
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Robertson, F.5
Cain, B.S.6
Harken, A.H.7
Banerjee, A.8
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20
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0030273367
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Differential effects of adenosine preconditioning on the post-ischemic rat myocardium
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Meldrum DR, JC Cleveland, BC Sheridan, RT Rowland, A Banerjee, and AH Harken: Differential effects of adenosine preconditioning on the post-ischemic rat myocardium. J Surg Res 65, 156-164 (1996)
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(1996)
J Surg Res
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Meldrum, D.R.1
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Banerjee, A.5
Harken, A.H.6
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21
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0030115716
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Cardiac surgical implications of calcium dyshomeostasis in the heart
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Meldrum DR, JC Cleveland, BC Sheridan, RT Rowland, A Banerjee, and AH Harken; Cardiac surgical implications of calcium dyshomeostasis in the heart. Ann Thorac Surg 61, 1273-1280 (1996)
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(1996)
Ann Thorac Surg
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Meldrum, D.R.1
Cleveland, J.C.2
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Rowland, R.T.4
Banerjee, A.5
Harken, A.H.6
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22
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0029858901
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Cardiac preconditioning with calcium: Clinically accessible myocardial protection
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Meldrum DR, JC Cleveland, BC Sheridan, RT Rowland, A Banerjee, and AH Harken: Cardiac preconditioning with calcium: Clinically accessible myocardial protection. J Thorac Cardiovasc Surg 112, 778-786 (1996)
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(1996)
J Thorac Cardiovasc Surg
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Meldrum, D.R.1
Cleveland, J.C.2
Sheridan, B.C.3
Rowland, R.T.4
Banerjee, A.5
Harken, A.H.6
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23
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0031148245
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Alpha-adrenergic activation of myocardial NFκB during hemorrhage
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Meldrum DR, JC Cleveland, BC Sheridan, RT Rowland, CH Selzman, A Banerjee, and AH Harken: Alpha-adrenergic activation of myocardial NFκB during hemorrhage. J Surg Res 69, 268-276 (1997)
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(1997)
J Surg Res
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Meldrum, D.R.1
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Sheridan, B.C.3
Rowland, R.T.4
Selzman, C.H.5
Banerjee, A.6
Harken, A.H.7
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24
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0031877074
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Hydrogen peroxide induces tumor necrosis factor alpha-mediated cardiac injury by a P38 mitogen-activated protein kinase-dependent mechanism
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Meldrum DR, CA Dinarello, JC Cleveland, Jr., BS Cain, BD Shames, X Meng, and AH Harken: Hydrogen peroxide induces tumor necrosis factor alpha-mediated cardiac injury by a P38 mitogen-activated protein kinase-dependent mechanism. Surgery 124, 291-296; discussion 297 (1998)
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Surgery
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Meldrum, D.R.1
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Cleveland Jr., J.C.3
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Shames, B.D.5
Meng, X.6
Harken, A.H.7
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25
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0345516048
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Ischemic preconditioning decreases post-ischemic myocardial TNF: Potential ultimate effector mechanism of preconditioning
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Meldrum DR, CA Dinarello, JC Cleveland, BS Cain, BD Shames, X Meng, and AH Harken: Ischemic preconditioning decreases post-ischemic myocardial TNF: Potential ultimate effector mechanism of preconditioning. Circulation 98, 214-219 (1998)
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(1998)
Circulation
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Meldrum, D.R.1
Dinarello, C.A.2
Cleveland, J.C.3
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Shames, B.D.5
Meng, X.6
Harken, A.H.7
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26
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0032167388
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Feature Article. Human myocardial TNF production following acute global ischemia and reperfusion injury in vivo
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Meldrum DR, CA Dinarello, JC Cleveland, BS Cain, BD Shames, X Meng, and AH Harken: Feature Article. Human myocardial TNF production following acute global ischemia and reperfusion injury in vivo. J Mol Cell Cardiol 30, 1683-1689 (1998)
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(1998)
J Mol Cell Cardiol
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Meldrum, D.R.1
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Cleveland, J.C.3
Cain, B.S.4
Shames, B.D.5
Meng, X.6
Harken, A.H.7
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27
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0344308819
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p38 MAP kinase mediates myocardial ischemia reperfusion injury
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In press
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Meldrum DR, CA Dinarello, JC Cleveland, L Shapiro, BC Sheridan, and AH Harken: p38 MAP kinase mediates myocardial ischemia reperfusion injury. Surg Forum In press (1997)
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(1997)
Surg Forum
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Meldrum, D.R.1
Dinarello, C.A.2
Cleveland, J.C.3
Shapiro, L.4
Sheridan, B.C.5
Harken, A.H.6
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0345516048
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Ischemic preconditioning decreases postischemic myocardial tumor necrosis factor-alpha production. Potential ultimate effector mechanism of preconditioning
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Meldrum DR, CA Dinarello, BD Shames, JC Cleveland, Jr., BS Cain, A Banerjee, X Meng, and AH Harken: Ischemic preconditioning decreases postischemic myocardial tumor necrosis factor-alpha production. Potential ultimate effector mechanism of preconditioning. Circulation 98, II214-218; discussion II218-219 (1998)
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(1998)
Circulation
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Meldrum, D.R.1
Dinarello, C.A.2
Shames, B.D.3
Cleveland Jr., J.C.4
Cain, B.S.5
Banerjee, A.6
Meng, X.7
Harken, A.H.8
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29
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0032772516
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Role of TNF in mediating renal insufficiency following cardiac surgery: Evidence of a postbypass cardiorenal syndrome
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Meldrum DR and KK Donnahoo: Role of TNF in mediating renal insufficiency following cardiac surgery: evidence of a postbypass cardiorenal syndrome. J Surg Res 85, 185-199 (1999)
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(1999)
J Surg Res
, vol.85
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Meldrum, D.R.1
Donnahoo, K.K.2
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0031445340
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L-arginine decreases alveolar macrophage proinflammatory monokine production during acute lung injury by a nitric oxide synthase-dependent mechanism
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Meldrum DR, RC McIntyre, BC Sheridan, JC Cleveland, Jr., DA Fullerton, and AH Harken: L-arginine decreases alveolar macrophage proinflammatory monokine production during acute lung injury by a nitric oxide synthase-dependent mechanism. J Trauma 43, 888-893 (1997)
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(1997)
J Trauma
, vol.43
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Meldrum, D.R.1
McIntyre, R.C.2
Sheridan, B.C.3
Cleveland Jr., J.C.4
Fullerton, D.A.5
Harken, A.H.6
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31
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0032167388
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Human myocardial tissue TNFalpha expression following acute global ischemia in vivo
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Meldrum DR, X Meng, CA Dinarello, A Ayala, BS Cain, BD Shames, L Ao, A Banerjee, and AH Harken: Human myocardial tissue TNFalpha expression following acute global ischemia in vivo. J Mol Cell Cardiol 30, 1683-1689 (1998)
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(1998)
J Mol Cell Cardiol
, vol.30
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Meldrum, D.R.1
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Dinarello, C.A.3
Ayala, A.4
Cain, B.S.5
Shames, B.D.6
Ao, L.7
Banerjee, A.8
Harken, A.H.9
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32
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0032816420
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Liposomal delivery of heat-shock protein 72 into the heart prevents endotoxin-induced myocardial contractile dysfunction
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Meldrum DR, X Meng, BD Shames, B Pomerantz, KK Donnahoo, A Banerjee, and AH Harken: Liposomal delivery of heat-shock protein 72 into the heart prevents endotoxin-induced myocardial contractile dysfunction. Surgery 126, 135-141 (1999)
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(1999)
Surgery
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Meldrum, D.R.1
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Banerjee, A.6
Harken, A.H.7
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33
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0032040329
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Tissue-specific protein kinase C isoforms differentially mediate macrophage TNFalpha and IL-1beta production
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Meldrum DR, X Meng, BC Sheridan, RC McIntyre, Jr., AH Harken, and A Banerjee: Tissue-specific protein kinase C isoforms differentially mediate macrophage TNFalpha and IL-1beta production. Shock 9, 256-260 (1998)
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(1998)
Shock
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Meldrum, D.R.1
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McIntyre Jr., R.C.4
Harken, A.H.5
Banerjee, A.6
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0027496594
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Cardiac preconditioning: Induction of endogenous tolerance to ischemia-reperfusion injury
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Meldrum DR, MB Mitchell, A Banerjee, and AH Harken: Cardiac preconditioning: Induction of endogenous tolerance to ischemia-reperfusion injury. Arch Surg 128, 1208-1211 (1993)
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(1993)
Arch Surg
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Meldrum, D.R.1
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Banerjee, A.3
Harken, A.H.4
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35
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0041347752
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On-pump coronary artery bypass surgery activates human myocardial NF-kappaB and increases TNF-alpha in the heart
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Meldrum DR, DA Partrick, JC Cleveland, Jr., R Shenkar, KK Meldrum, A Raiesdana, A Ayala, JW Brown, and AH Harken: On-pump coronary artery bypass surgery activates human myocardial NF-kappaB and increases TNF-alpha in the heart. J Surg Res 112, 175-179 (2003)
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J Surg Res
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Meldrum, D.R.1
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Meldrum, K.K.5
Raiesdana, A.6
Ayala, A.7
Brown, J.W.8
Harken, A.H.9
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36
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0031257781
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Hemorrhage activates myocardial NFkappaB and increases TNF-alpha in the heart
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Meldrum DR, R Shenkar, BC Sheridan, BS Cain, E Abraham, and AH Harken: Hemorrhage activates myocardial NFkappaB and increases TNF-alpha in the heart. J Mol Cell Cardiol 29, 2849-2854 (1997)
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(1997)
J Mol Cell Cardiol
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Meldrum, D.R.1
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Abraham, E.5
Harken, A.H.6
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37
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0029903746
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Neutrophils are required for endotoxin induced myocardial cross-tolerance to ischemia-reperfusion injury
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Meldrum DR, BC Sheridan, JC Cleveland, DA Fullerton, A Banerjee, and AH Harken: Neutrophils are required for endotoxin induced myocardial cross-tolerance to ischemia-reperfusion injury. Arch Surg 131, 1203-1208 (1996)
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(1996)
Arch Surg
, vol.131
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Meldrum, D.R.1
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Harken, A.H.6
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38
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0034880612
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p38 MAPK mediates renal tubular cell TNF-alpha production and TNF-alpha-dependent apoptosis during simulated ischemia
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Meldrum KK, DR Meldrum, KL Hile, EB Yerkes, A Ayala, MP Cain, RC Rink, AJ Casale, and MA Kaefer: p38 MAPK mediates renal tubular cell TNF-alpha production and TNF-alpha-dependent apoptosis during simulated ischemia. Am J Physiol Cell Physiol 281, C563-570 (2001)
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(2001)
Am J Physiol Cell Physiol
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Meldrum, K.K.1
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Rink, R.C.7
Casale, A.J.8
Kaefer, M.A.9
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39
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0036085203
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TNF-alpha-dependent bilateral renal injury is induced by unilateral renal ischemia-reperfusion
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Meldrum KK, DR Meldrum, X Meng, L Ao, and AH Harken: TNF-alpha-dependent bilateral renal injury is induced by unilateral renal ischemia-reperfusion. Am J Physiol Heart Circ Physiol 282, H540-546 (2002)
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(2002)
Am J Physiol Heart Circ Physiol
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Meldrum, K.K.1
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40
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0034804016
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Heat shock prevents simulated ischemia-induced apoptosis in renal tubular cells via a PKC-dependent mechanism
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Meldrum KK, DR Meldrum, SF Sezen, JK Crone, and AL Burnett: Heat shock prevents simulated ischemia-induced apoptosis in renal tubular cells via a PKC-dependent mechanism. Am J Physiol Regul Integr Comp Physiol 281, R359-364 (2001)
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(2001)
Am J Physiol Regul Integr Comp Physiol
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Meldrum, K.K.1
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41
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0035917840
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Tech. Sight. Sequencing genomes and beyond
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Meldrum DR: Tech. Sight. Sequencing genomes and beyond. Science 292, 515-517 (2001)
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(2001)
Science
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Meldrum, D.R.1
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0037458926
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Liposomal delivery of heat shock protein 72 into renal tubular cells blocks nuclear factor-kappaB activation, tumor necrosis factor-alpha production, and subsequent ischemia-induced apoptosis
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Meldrum KK, AL Burnett, X Meng, R Misseri, MB Shaw, JP Gearhart, and DR Meldrum: Liposomal delivery of heat shock protein 72 into renal tubular cells blocks nuclear factor-kappaB activation, tumor necrosis factor-alpha production, and subsequent ischemia-induced apoptosis. Circ Res 92, 293-299 (2003)
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(2003)
Circ Res
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Meldrum, K.K.1
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Meldrum, D.R.7
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43
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0022374305
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Sex hormones, immune responses, and autoimmune diseases. Mechanisms of sex hormone action
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Tumor necrosis factor-alpha gene and protein expression in adult feline myocardium after endotoxin administration
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Tumor necrosis factor alpha and interleukin 1beta are responsible for in vitro myocardial cell depression induced by human septic shock serum
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IL-1beta and IL-6 act synergistically with TNF-alpha to alter cardiac contractile function after burn trauma
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Maass DL, J White, and JW Horton: IL-1beta and IL-6 act synergistically with TNF-alpha to alter cardiac contractile function after burn trauma. Shock 18, 360-366 (2002)
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