Cardiac myocytes produce interleukin-6 in culture and in viable border zone of reperfused infarctions

Circulation

Volumn 99, Issue 4, 1999, Pages 546-551

  Gwechenberger, Marianne ^a   Mendoza, Leonardo H ^a   Youker, Keith A ^a   Frangogiannis, Nikolaos G ^b   Wayne Smith, C ^b   Michael, Lloyd H ^a   Entman, Mark L ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b Collateral Therapeutics ^*  (United States)

Author keywords

Interleukins; Myocardial infarction; Myocytes; Reperfusion

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOG; FEMALE; GENE EXPRESSION; HEART INFARCTION; HEART MUSCLE CELL; IN SITU HYBRIDIZATION; LYMPH; MALE; MUSCLE FIBER CULTURE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; REPERFUSION INJURY;

EID: 0033514260     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.99.4.546     Document Type: Article

References (51)

1. Go LO, Murry CE, Richard VJ, Weischedel GR, Jennings RB, Reimer KA. Myocardial neutrophil accumulation during repcrfusion after reversible or irreversible ischémie injury. Am J Physiol. 1988;255:H!I77-H1198.
2. Mullane KM, Smith CW. In: Piper, HM, ed. The Role of Leukocytes in Ischémie Damage, Reperfusion Injury and Repair of the Myocardium: Pathophysiology of Severe Ischémie Myocardial Injury. Dordrecht, The Netherlands: Kluwer Academic Publishers; 1990:239-267.
3. Dreyer WJ, Michael LH, West MS, Smith CW, Rothlein R, Rossen RD, Anderson DC, Entman ML. Neutrophil accumulation in ischcmic canine myocardium: insights into the time course, distribution and mechanism of localization during early reperfusion. Circulation. 1991:84:400-411.
4. Entman ML, Smith CW. Postreperfusion inflammation: a model for reaction to injury in cardiovascular disease. Cardiovasc Res. 1994;28: 1301-1311.
5. Hawkins HK, Entman ML, Zhu JY, Youker KA, Berens K, Dore M, Smith CW. Acute inflammatory reaction after myocardial ischémie injury and reperfusion: development and use of a neutrophil-spccific antibody. Am J Paihol. 1996; 148:1957-1969.
6. Baumgarten W. Infarction of the heart. Am J Physiol. 1899;2:243-265.
7. Gruppo Italiano per lo studio délia Streptochinasi nell'Infarto Miocardico. Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction. Lancet. 1986:1:397-401.
8. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Randomised trial of intravenous streptokinase, oral aspirin, both or neither among 17,187 cases of suspected myocardial infarction: ISIS-2. Lancet. 1988:2:349-360.
9. Neuhaus KL, Feuerer W, Jeep Tebbe S, Niederer W, Vogt A, Tebbc U. Improved thrombolysis with a modified dose regimen of rccombinant tissue type plasminogen activator. J Am Coll Cardiol. 1989:14:1566-1569.
10. Guillen I, Blanes M, Gomez-Lechon MJ, Castell JV. Cytokine signaling during myocardial infarction: sequential appearance of IL-1 beta and IL-6. Am J Physiol. I995;269:R229-R235.
11. Ikeda U, Ohkawa F, Seino Y, Yamamoto K, Hidaka Y, Kasahara T, Kawai T, Shimada K. Serum InterIeukin-6 becomes elevated in acute myocardial infarction. J Mol Cell Canliol. 1992;24:579-584.
12. Neumann FJ, Ott I, Gawaz M, Richardt G, Holzapfel H, Jochum M, Schoemig A. Cardiac release of cytokines and inflammatory responses in acute myocardial infarction. Circulation. 1995;92:748-755.
13. Entman ML, Youker KA, Shappell SB, Siegel C, Rothlein R, Dreyer WJ, Schmalstieg FC, Smith CW. Neutrophil adherence to isolated adult canine myocytes: evidence for a CD 18 dependent mechanism. J Clin Invest. 1990;85:1497-1506.
14. Smith CW, Entman ML, Lane CL, Beaudet AL, Ty TI, Youker KA, Hawkins HK, Anderson DC. Adherence of neutrophils to canine cardiac myocytes in vitro is dependent on intercellular adhesion molecule-1. J Clin Invest. 199I;88:I2I6-1223.
15. Entman ML, Youker KA, Shoji T, Kukielka GL, Shappell SB, Taylor AA, Smith CW. Neutrophil induced oxidative injury of cardiac myocytes: a compartmented system requiring CDllb/CD18-ICAM-I adherence. J Clin Invest. 1992;90:1335-1345.
16. Michael L, Lewis R, Brandon T, Entman M. Cardiac lymph flow in conscious dogs. Am J Physiol. I979;237(//car/ Circ Physiol 6):H311-H317.
17. Michael LH, Hunt JR, Weilbacher D, Ferryman MB, Roberts R, Lewis RM, Entman ML. Creatine kinase and phosphorylase in cardiac lymph: coronary occlusion and reperfusion. Am J Physiol. 1985;248: H350-H359.
18. Youker KA, Smith CW, Anderson DC, Miller D, Michael LH, Rossen RD, Entman ML. Neutrophil adherence to isolated adult cardiac myocytes: induction by cardiac lymph collected during ischemia and reperfusion. J Clin Invest. 1992;89:602-609.
19. Kukielka GL, Youker KA, Hawkins HK, Perrard JL, Micheal LH, Ballantyne CM, Smith CW, Entman ML. Regulation of ICAM-1 and IL-6 in the myocardial ischemia: effects of reperfusion. Ann N Y Acad Sei. 1994;723:258-270.
20. Youker KA, Hawkins HK, Kukielka GL, Perrard JL, Michael LH, Ballanlyne CM, Smith CW, Entman ML. Molecular evidence for induction of intercellular adhesion molecule 1 in the viable border zone associated with ischemia reperfusion injury of the dog heart. Circulation. 1994;89:2736-2746.
21. Kukielka GL, Hawkins HK, Michael LH, Manning AM, Lane CL, Entman ML, Smith CW, Anderson DC. Regulation of intercellular adhesion molecule-1 (ICAM-1) in ischémie and reperfused canine myocardium. J Clin Invest. 1993;92:1504-1516.
22. Kukielka GL, Smith CW, Manning AM, Youker K, Michael LH, Entman ML. Induction of interIeukin-6 synthesis in the myocardium: potential role in postreperfusion inflammatory injury. Circulation. 1995;92: 1866-1875.
23. Akira S, Taga T, Kishimoto T. Interleukin-6 in biology and medicine. Adv Immunol. I993;54:l-78.
24. Kukielka GL, Youker KA, Michael LH, Kumar AG, Ballantyne CM, Smith CW, Entman ML. Role of early reperfusion in the induction of adhesion molecules and cytokines in previously ischémie myocardium. Mol Cell Biochem. 1995;147:5-12.
25. Birdsall HH, Green DM, Trial J, Youker KA, Bums AR, MacKay CR, LaRosa GL, Hawkins HK, Smith CW, Michael LH, Entman ML, Rossen RD. Complement C5a, TGF-01, and MCP-1, in sequence, induce migration of monocytes into ischémie canine myocardium within the first one to five hours after reperfusion. Circulation. 1997;95:684-692.
26. Heymann MA, Payne BD, Hoffmann JIE, Rudolph AM. Blood flow measurements with radionuclide labeled particles. Prog Cardiovasc Dis. 1977;20:55-78.
27. Goddard-Finegold J, Michael LH. Cerebral blood flow and experimental intraventricular hemorrhage. Pediatr Res. 1984;18:7-11.
28. Chomczynski P, Sacchi N. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 1987;I62:156-159.
29. Sambrook J, Fritsch EF, Maniatis T. Molecular Cloning: A Laboratory Manual Cold Spring Harbor, NY: Cold Spring Harbor Laboratory; 1989:545.
30. Meerbaum S, Haendchen RV, Corday E, Povzhitkov M, Fishbein MC, Y-Rit J, Land T, Uchiyama T, Aosaki N, Broffman J. Hypothermie coronary venous phased retroperfusion: a closed-chest treatment of acute regional myocardial ischemia. Circulation. 1982;65:1435-1445.
31. Fishbein MC, Hare CA, Gissen SA, Spadaro J, Maclean D, Maroko PR. Identification and quantification of histcchemical border zones during the evolution of myocardial infarction in the rat Cardiovasc Res. 19SO;14:41-49.
32. Block ML, Said JW, Siegel RJ, Fishbein MC. Myocardial myoglobin following coronary artery occlusion: an immunohistochemical Study. Am J Pathol. 1983;! 11:374-379.
33. Yamauchi-Takihara K, Ihara Y, Ogata A, Yoshizaki K, Azuma J, Kishimoto T. Hypoxie stress induces cardiac myocyte-derived interIeukin-6. Circulation. 1995;91:1520-1524.
34. Hirschl MM, Gwechenberger M, Binder T, Graf S, Stefenelli T, Rauscha F, Laggner AN, Sochor H. Assessment of myocardial injury by tumor necrosis factor alpha measurements in acute myocardial infarction. Ear Heart J. 1996;17:1852-1859.
35. Lissoni P, Pelizzoni F, Mauri O, Perego M, Pittalis S, Barni S. Enhanced secretion of tumor necrosis factor in patients with myocardial infarction. EurJMed. 1992; 1:277-280.
36. Frangogiannis NG, Lindsey ML, Michael LH, Youker KA, Bressler RB, Mendoza LH, Spengler RN, Smith CW, Entman ML. Resident cardiac mast cells degranulate and release preformed TNF-o initiating the cytokine cascade in experimental canine myocardial ischemia/reperfusion. Circulation. 1998;98:699 -710.
37. Sanceau J, Kaisho T, Hirano T, Wietzerbin J. Triggering of the human interIeukin-6 gene by Interferon gamma and tumor necrosis factor alpha in monocytic cells involves cooperation between interferon regulatory factor-1, NfkB and Spl transcription factors. J Biol Client. 1995;270: 27920-27931.
38. Podor TJ, Jink FR, Loskutoff DJ, Carson DA. Lotz M. Human endothelial cells produce 1L-6: lack of responses to exogenous 1L-6. Ann N Y AcadSci. I989;557:374-385.
39. Elias JA, Lentz V. IL-1 and tumor necrosis factor synergistically stimulate fibroblast 1L-6 production and stabilize IL-6 messenger RNA. Jlmmunol. 1990;145:161-166.
40. Youker KA, Frangogiannis N, Lindsey M, Smith CW, Entman ML. Adhesion molecule induction and expression in neutrophil-induced myocardial injury. In: Schultheiss HP, Schwimmbeck P, eds. Tlie Role of Immune Mechanisms in Cardiovascular Disease. Berlin: Springer-Verlag; 1997: 125-137.
41. Finkel MS, Oddis CV, Jacob TD, Watkins SC, Hauler BG, Simmons RL. Negative inotropic effect of cytokines on the heart mediated by nitric oxide. Science. 1992;257:387-389.
42. Finkel MS, Hoffman RA, Shen L, Oddis CV, Simmons RL, Hattler BG. Interleukin-6 (IL-6) as a mediator of stunned myocardium. Am J Cordial. 1993;71:I231-1323.
43. Kinugawa K, Takahashi T, Kohmoto O, Yao A, Aoyagi T, Momomura S, Hirata Y, Serizawa T. Nitric oxide-mediated effects of interleukin-6 on [Ca3], and cell contraction in cultured chick ventricular myocytes. Circ Res. 1994;75:285-295.
44. Kishimoto T, Taga T, Akira S. Cytokine signal transduction. Cell. 1994; 76:253-262.
45. Pennica D, King KL, Shaw KJ, Luis E, Rullamas J, Luoh SM, Darbonne \VG, Knutzow DS, Yen R, Chien KR. Expression cloning of cardiotrophin-1, a cytokine that induces cardiac myocyte hypertrophy. Proc Natl Acad Sei USA. 1995;92:1142-1146.
46. Kodama H, Fukuda K, Pan J, Makino S, Baba A, Hori S, Ogawa S. Leukemia inhibitory factor, a potent hypertrophie cytokine, activates the JAK/STAT pathway in rat cardiomyocytes. Circ Res. 1997;81:656-663.
47. Hirato H, Yoshida K, Kishimoto T, Taga T. Continuous activation of gp 130, a signal transducing receptor component for interleukin-6 related cytokines, causes myocardial hypertrophy in mice. Proc Natl Acad Sei USA. 1995;92:4862-4866.
48. Sheng Z, Pennica D, Wood WI, Chien KR. Cardiotrophin-1 displays early expression in the murine heart tube and promotes cardiac myocyte survival. Development. I996;122:419-428.
49. Sheng Z, Knowlton K, Chen J, Hoshijiama M, Brown JH, Chien KR. Cardiotrophin-1 (CT-1) inhibition of cardiac myocyte apoptosis via a mitogen-activated protein-kinase dependent pathway: divergence from downstream CT-1 signals for myocardial cell hypertrophy. J Bio! Client. 1997:272:5783-5791.
50. Schwarze MMK, Hawley RG. Prevention of myeloma cell apoptosis by ectopic be 1-2 expression or interleukin-6 mediated upregulation ofbcl-xL. Cancer Res. 1995;55:2262-2265.
51. Fujio Y, Kunisada K, Hirota H, Yamauchi-Takihara K, Kishimoto T. Signals through gp!30 upregulate bcl-x gene expression via STAT-1 binding ciVelement in cardiac myocyte. J Clin Invest. I997;99: 2898-2905.