Gene delivery of Kir6.2/SUR2A in conjunction with pinacidil handles intracellular Ca2+ homeostasis under metabolic stress

FASEB Journal

Volumn 13, Issue 8, 1999, Pages 923-929

  Jovanović, Nenad ^a   Jovanović, Sofija ^a   Jovanović, Aleksandar ^a   Terzic, Andre ^a  

^a MAYO CLINIC   (United States)

Author keywords

Gene therapy; Ischemia; K(ATP) channels; Potassium channel opener

Indexed keywords

2,4 DINITROPHENOL; 5 HYDROXYDECANOIC ACID; CALCIUM; PINACIDIL;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CONTROLLED STUDY; GENE TARGETING; HYPOXIA; METABOLIC DISORDER; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; REOXYGENATION;

EID: 0032948514     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.13.8.923     Document Type: Article

References (45)

1. Granger, D. N., and Korthius, R. J. (1995) Physiologic mechanisms of postischemic tissue injury. Annu. Rev. Physiol. 57, 311-332
2. Kristian, T., and Siesjo, B. K. (1998) Calcium in ischemic cell death. Stroke 29, 705-718
3. Maxwell, S. R. J., and Lip, G. Y. H. (1997) Reperfusion injury: a review of the pathophysiology, clinical manifestations and therapeutic options. Int. J. Cardiol. 58, 95-117
4. Aguilar-Bryan, L., Nichols, C. G., Wechsler, S. W., Clement, J. P., Boyd, A. E., Gonzales, G., Hererra-Sosa, H., Nguy, K., Bryan, J., and Nelson D. A. (1995) Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion. Science 268, 423-426
5. KATP: an inward rectifier subunit plus the sulfonylurea receptor. Science 270, 1166-1170
6. Inagaki, N., Gonoi, T., Clement, J. P., Wang, C. Z., Aguilar-Bryan, L., Bryan, J., and Seino, S. (1996) A family of sulfonylurea receptors determines the pharmacological properties of ATP-sensitive K+ channels. Neuron 16, 1011-1017
7. + channel. J. Biol. Chem. 271, 24321-24324
8. Nichols, C. G., Shyng, S. L., Nestorowicz, A., Glaser, B., Clement, J. P., Gonzales, G., Aguilar-Bryan, L., Permutt, M. A., and Bryan, J. (1996) Adenosine diphosphate as an intracellular regulator of insulin secretion. Science 272, 1785-1787
9. Clement, J. P., Kunjilwar, K., Gonzales, G., Schwanstecher, M., Panten, U., Aguilar-Bryan, L., and Bryan, J. (1997) Association and stoichiometry of KATP channel subunits. Neuron 18, 827-838
10. + channel behavior. J. Membr. Biol. 159, 161-168
11. + channel. Mol. Cell. Biol. 18, 1652-1659
12. + channels. Trends Neurosci. 21, 288-294
13. Lauritzen, I., De Weille, J. R, and M. Lazdunski. (1997) The potassium channel opener (-) cromakalim prevents glutamate-induced cell death in hippocampal neurons. J. Neurochem. 69, 1570-1579
14. Liu, Y. G., Sato, T., Orourke, B., and Marban, E. (1998) Mitochondrial ATP-dependent potassium channels - novel effectors of cardioprotection. Circulation 97, 2463-2469
15. + channel subunits confer resistance towards chemical hypoxia-reoxygenation injury. Circulation 98, 1548-1555
16. Jovanović, A., Jovanović, S., Carrasco, A. J., and Terzic, A. (1998) Acquired resistance of a mammalian cell line to hypoxia-reoxygenation through co-transfection of Kir6.2 and SUR1 clones. Lab. Invest. 78, 1101-1107
17. Miki, T., Nagashima, K., Tashiro, F., Kotake, K., Yoshitami, H., Tamamoto, A., Gonoi, T., Iwanaga, T., Miyazaki, J., and Seino, S. (1998) Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice. Proc. Natl. Acad. Sci. U. S. A. 95, 10402-10406
18. + channel expressed in a mammalian cell line, HEK293T cells. Pfluegers Arch. 435, 595-603
19. Lopez, J. R., Jovanovic, A., and Terzic, A. (1995) Spontaneous calcium waves without contraction in cardiac myocytes. Biochem. Biophys. Res. Commun. 214, 781-787
20. 2+ domain-dependent protective action of adenosine in a cardiomyocytes. Eur. J. Pharmacol. 298, 63-69
21. Jovanovic, A., Alekseev, A. E., Lopez, J. R., Shen, W. K., and Terzic, A. (1997) Adenosine prevents hyperkalemia-induced calcium loading in cardiac cells: relevance for cardioplegia. Ann. Thorac. Surg. 63, 153-161
22. 2+ loading in cardiomyocytes. Eur. J. Pharmacol. 308, 343-349
23. + channel opening drugs. Am. J. Physiol. 269, C525-C545
24. + channel by 5-hydroxydecanoate in guinea pig ventricular myocytes. J. Pharmacol. Exp. Ther. 260, 702-708
25. 2+ pump. J. Biol. Chem. 267, 12545-12551
26. Hansford, R. G., and Lakatta, E. G. (1987) Ryanodine releases calcium from sarcoplasmatic reticulum in calcium-tolerant rat cardiac myocytes. J. Physiol. (London) 390, 453-467
27. 2+ pool in the isolated hepatocytes. FEBS Lett. 313, 39-42
28. Kim, J. S., and Southard, J. H. (1998) Alterations in cellular calcium and mitochondrial functions in the rat liver during cold preservation. Transplantation 65, 369-375
29. Miller, T. W., and Tormey, J. McD. (1995) Subcellular calcium pools of ischaemic and reperfused myocardium characterised by electron probe. Cardiovasc. Res. 29, 85-94
30. 2+ antagonists. J. Mol. Cell. Cardiol. 18 (Suppl. 4), 71-75
31. Kusuoka, H., Correti, M. C., Koretsune, Y., and Marban, E. (1998) Mechanism for the cardioprotective effects of the calcium channel blocker clentiazem during ischemia and reperfusion. Jpn. Circ. J. 62, 611-616
32. Levitsky, J., Gurell, D., Frishman, W. H. (1998) Sodium ion hydrogen ion exchange inhibition - a new pharmacologic approach to myocardial ischemia and reperfusion injury. J. Clin. Pharmacol. 38, 887-897
33. Zwack, R. M., Zhou, W., Zhang, Y., Darby, C. J., Dudus, L., Halldorson, J., Oberley, L., and Engelhardt, J. F. (1998) Redox gene therapy for ischemia/reperfusion injury of the liver reduces API and NF-κB activation. Nature Med. 4, 698-704
34. Daniel, C., Erzurum, S. C., Prayssac, P., Eissa, N. T., Crystal, R. G., Herve, P., Baudet, B., Mazmanian, M., and Lemerchand, P. (1998) Gene therapy for oxidant injury-related diseases: adenovirus-mediated transfer of superoxide dismutase and catalase cDNAs protects against hyperoxia but not against ischemia-reperfusion lung injury. Hum. Gene Ther. 9, 1487-1496
35. French, BA. (1998) Gene therapy and cardiovascular diseases. Curr. Opin. Cardiol. 13, 205-213
36. ATP channel. Proc. Natl. Acad. Sci U. S. A. 94, 11969-11973
37. Gross, G. J. (1995) ATP-sensitive potassium channels and myocardial preconditioning. Basic Res. Cardiol. 90, 85-88
38. Hearse, D. J. (1995) Activation of ATP-sensitive potassium channels: a novel pharmacological approach to myocardial protection. Cardiovasc. Res. 30, 1-17
39. Lopez, J. R., Jahangir, R., Jahangir, A., Shen, W. K., and Terzic, A. (1996) Potassium channel openers prevent potassium-induced calcium loading of cardiac cells: possible implications in cardioplegia. J. Thorac. Cardiovasc. Surg. 112, 820-831
40. ATP) openers in models of myocardial ischemia and reperfusion. Can. J. Physiol. Pharmacol 75, 309-315
41. ATP-channel openers protect against increased cytosolic calcium during ischemia and reperfusion. J. Mol. Cell. Cardiol. 27, 1809-1817
42. 2+ release from IP3-sensitive internal stores in a green monkey kidney cell line. J. Physiol. (London) 493, 371-384
43. Balastrino, M. (1995) Pathophysiology of anoxic depolarization: new findings and working hypothesis. J. Neurosci. Methods 59, 99-103
44. Yanagisawa, T., Teshigawara, T., and Taira, N. (1990) Cytoplasmic calcium and the relaxation of canine coronary arterial smooth muscle produced by cromakalim, pinacidil and nicorandil. Br. J. Pharmacol. 101, 157-165
45. + channels modulate cardiac mitochondrial function. Am. J. Physiol. 275, H1567-H1576