Anabolic steroids induce injury and apoptosis of differentiated skeletal muscle

Journal of Neuroscience Research

Volumn 47, Issue 2, 1997, Pages 186-197

  Abu Shakra, S ^a   Alhalabi, M S ^a   Nachtman, F C ^a   Schemidt, R A ^a   Brusilow, W S A ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

anabolic steroids; apoptosis; cellular ATP; injury; skeletal muscle

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANABOLIC AGENT; CELL DNA; STANOZOLOL;

ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; DNA STRAND BREAKAGE; HORMONE ACTION; MOUSE; MUSCLE DEVELOPMENT; MUSCLE INJURY; NONHUMAN; PRIORITY JOURNAL; SKELETAL MUSCLE;

ADENOSINE TRIPHOSPHATE; ANABOLIC AGENTS; ANIMALS; APOPTOSIS; CALCIMYCIN; CELL DIFFERENTIATION; CELL LINE; DNA FRAGMENTATION; DRUG EVALUATION, PRECLINICAL; IONOPHORES; KINETICS; MICE; MUSCLE, SKELETAL; NECROSIS; NUCLEOSOMES; STANOZOLOL;

EID: 0031018427     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19970115)47:2<186::AID-JNR7>3.0.CO;2-B     Document Type: Article

References (50)

1. Abu-Shakra SR, Nachtman FC (1995): Anabolic steroids induce skeletal muscle injury and immediate early gene expression through a receptor-independent mechanism. Ann NY Acad Sci 761: 395-399.
2. Abu-Shakra SR, Cole AJ, Adams RN, Drachman DB (1994): Cholinergic stimulation of skeletal muscle cells induces rapid immediate early gene expression: Role of intracellular calcium. Mol Brain Res 26:55-60.
3. Ankarcrona M, Dypbukt JM, Bonfoco E, Zhivotovsky B, Orrenuis S, Lipton SA, Nictoera P (1995): Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function. Neuron 15:961-973.
4. Ayala A, Herdon CD, Lehman DL, DeMaso CM, Ayala CA, Chaudry IH (1995): The induction of accelerated thymic programmed cell death during polymicrobial sepsis: Control by corticosteroids but not tumor necrosis factor. Shock 3:259-267.
5. Behrendt H, Boffin H (1977): Myocardial cell lesions caused by an anabolic hormone. Cell Tissue Res 181:423-426.
6. Blin N, Stafford DW (1976): A general method for isolation of high molecular weight DNA from eukaryotes. Nucleic Acids Res 3:2303.
7. Buerke M, Murohara T, Skurk C, Nuss C, Tomaselli K, Lefer AM (1995): Cardioprotective effect of insulin-like growth factor I in myocardial ischemia followed by reperfusion. Proc Natl Acad Sci 92:8031-8035.
8. Chomczynski P (1993): A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. Biotechniques 15:532-537.
9. Ciancio G, Pollack A, Taupier MA, Block NL, Irvin GL III (1988): Measurement of cell-cycle phase-specific cell death using Hoechst 33342 and propidium iodide: Preservation by ethanol fixation. J Histochem Cytochem 9:1147-1152.
10. Cohen JJ, Duke RC (1984): Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death. J Immunol 132:38-42.
11. Ellwart JW, Dörmer P (1990): Vitality measurement using spectrum shift in Hoechst 33342 stained cells. Cytometry 11:239-243.
12. Fidzianska A, Kaminska A (1991): Apoptosis: A basic pathological reaction of injured neonatal muscle. Pediatr Pathol 11:421-429.
13. Gavrieli Y, Sherman Y, Ben-Sasson SA (1992): Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119:493-500.
14. Gottlieb RA, Burleson KO, Kloner RA, Babior BM, Engler RL (1994): Reperfusion injury induces apoptosis in rabbit cardiomyocytes. J Clin Invest 94:1621-1628.
15. Haupt HA (1993): Anabolic steroids and growth hormone. Am J Sports Med 21:468-474.
16. Heron A, Pollard H, Dessi F, Moreau J, Lasbennes F, Ben-Ari Y, Charriaut-Marlangue C (1993): Regional variability in DNA fragmentation after global ischemia evidenced by combined histological and gel electrophoresis observations in the rat brain. J Neurochem 61:1973-1976.
17. Jondal M, Okret S, McConkey D (1993): Killing of immature CD4+ CD8+ thymocytes in vivo by anti-CD3 or 5′-(N-ethyl)-carboxamide adenosine is blocked by glucocorticoid receptor anatagonist RU 486. Eur J Immunol 23:1246-1250.
18. Kennedy MC, Lawrence C (1993): Anabolic steroid abuse and cardiac death. Med J Aust 158:346-348.
19. Kerr JF, Searle J (1973): Deletion of cells by apoptosis during castration-induced involution of the rat prostate. Virchows Arch B Cell Pathol 13:87-102.
20. Kerr JFR, Wyllie AH, Currie AR (1972): Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239-257.
21. Kibble MW, Ross MB (1987): Adverse effects of anabolic steroids in athletes. Clin Pharmacol Ther 6:686-692.
22. 1 lymphocytes by non-stoichiometric Hoechst fluorochrome binding. Cytometry 11:386-394.
23. Kyprianou N, English HF, Issacs JT (1990): Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation. Cancer Res 50:3748-3753.
24. Linnik MD, Zobrist RH, Hatfield MD (1993): Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats. Stroke 24:2002-2009.
25. Lowry OH, Rosebrough LNT, Farr AL, Randall RJ (1951): Protein measurement with the folin phenol reagent. J Biol Chem 193: 265-275.
26. Maron BJ, Roberts WC, McAllister HA, Rosing DR, Epstein SE (1980): Sudden death in young athletes. Circulation 62:218-229.
27. Martin DP, Schmidt RE, DiStefano PS, Lowry OH, Carter JG, Johnson EM Jr (1988): Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation. J Cell Biol 106:829-844.
28. Matsuda R, Nishikawa A, Tanaka H (1995): Visualization of dystrophic muscle fibers in mdx mouse by vital staining with Evans blue: Evidence of apoptosis in dystrophin-deficient muscle. J Biochem 118:959-964.
29. McEwen BS (1991): Non-genomic and genomic effects of steroids on neural activity. Trends Pharmacol Sci 12:141-146.
30. McNutt RA, Ferenchick GS, Kirlin PC, Hamlin NJ (1988): Acute myocardial infarction in a 22-year-old world class weight lifter using anabolic steroids. Am J Cardiol 62:164.
31. Nachtman FC, Alhalabi MS, Abu-Shakra SR (1995): Calcium-mediated injury of skeletal muscle leads to necrotic cell death not apoptosis [Abstract]. Neurology 45:A184.
32. Oppenheim RW, Prevette D, Tytell M, Homma S (1990): Naturally occurring and induced neuronal death in the chick embryo in vivo requires protein and RNA synthesis: Evidence for the role of cell death genes. Dev Biol 138:104-113.
33. Polunovsky VA, Wendt CH, Ingbar DH, Peterson MS, Bitterman PB (1994): Induction of endothelial cell apoptosis by TNF-α: Modulation by inhibitors of protein synthesis. Exp Cell Res 214: 584-594.
34. Portera-Cailliau C, Hedreen JC, Price DL, Koliatsos VE (1995): Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models. J Neurosci 15:3775-3787.
35. Ratan RR, Murphy TH, Baraban JM (1994): Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione. J Neurosci 14:4382-4385.
36. Sandri M, Carraro U, Podhorska-Okolov M, Rizzi C, Arslan P, Monti D, Franceschi C (1995): Apoptosis, DNA damage and ubiquitin expression in normal and mdx muscle fibers after exercise. FEBS Lett 373:291-295.
37. Sanford NL, Searle JW, Kerr JFR (1984): Successive waves of apoptosis in rat prostate after repeated withdrawal of testosterone stimulation. Pathology 16:406-410.
38. 0 proton-translocating ATPases. J Biol Chem 266: 18567-18572.
39. Schwartz LM (1992): Insect muscle as a model for programmed cell death. J Neurobiol 23:1312-1326.
40. Sharov VG, Sabbah HN, Shimoyama H, Goussev AV, Lescn M, Goldstein S (1996): Evidence of cardiocyte apoptosis in myocardium of dogs with chronic heart failure. Am J Pathol 148: 141-149.
41. 2 and nitric oxide-mediated oxidative stress induce apoptosis in rat skeletal muscle myoblasts. J Neuropathol Exp Neurol 55:36-43.
42. Tanaka M, Ito H, Adachi S, Akimoto H, Nishikawa T, Kasajima T, Marumo F, Hiroe M (1994): Hypoxia induces apoptosis with enhanced expression of fas antigen messenger RNA in cultured neonatal rat cardiomyocytes. Circ Res 75:426-433.
43. Thompson EB, Thulasi R, Saeed MF, Johnson BH (1995): Glucocorticoid antagonist RU 486 reverses agonist-induced apoptosis and c-myc repression in human leukemic CEM-C7 cells. Ann NY Acad Sci 761:261-275.
44. Tidball JG, Albrecht DE, Lokensgard BE, Spencer MJ (1995): Apoptosis precedes necrosis of dystrophin-deficient muscle. J Cell Sci 108:2197-2204.
45. Tomei LD, Shapiro JP, Cope FO (1993): Apoptosis in C3H/10TI/2 mouse embryonic cells: Evidence for internucleosomal DNA modification in the absence of double-strand cleavage. Proc Natl Acad Sci USA 90:853-857.
46. Wadewitz AG, Lockshin RA (1988): Programmed cell death: Dying cells synthesize a coordinated, unique set of proteins in two different episodes of cell death. FEBS Lett 241:19-23.
47. Wijsman JH, Jonker RR, Keijzer R, Van De Velde CJH, Cornelisse CJ, Van Dierendonck JH (1993): A new method to detect apoptosis in paraffin sections: In situ end-labeling of fragmented DNA. J Histochem Cytochem 41:7-12.
48. Wyllie AH (1980): Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284:555-556.
49. Wyllie AH, Kerr JFR, Currie AR (1980): Cell death: The significance of apoptosis. Int Rev Cytol 68:251-306.
50. Wyllie AH, Morris RG, Smith AL, Dunlop D (1984): Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis. J Pathol 142:67-77.