Attenuation of postischemic reperfusion injury is related to prevention of [Ca2+](m) overload in rat hearts

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 271, Issue 5 40-5, 1996, Pages

  Miyamae, Masami ^b   Camacho, S Albert ^b   Weiner, Michael W ^b   Figueredo, Vincent M ^a  

^a SAN FRANCISCO GENERAL HOSPITAL   (United States)

^b NONE

Author keywords

indo 1 fluorescence; intracellular calcium; myocardium; ruthenium red

Indexed keywords

CALCIUM ION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; MALE; NONHUMAN; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

EID: 0029949676     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1996.271.5.h2145     Document Type: Article

References (41)

1. Allard, M. F., J. D. Flint, J. C. English, S. L. Henning, M. C. Salamanca, C. T. Kamimura, and D. R. English. Calcium overload during reperfusion is accelerated in isolated hypertrophied rat hearts. J. Mol. Cell. Cardiol. 26: 1551-1563, 1994.
2. 2+ under various conditions. J. Mol. Cell. Cardiol. 24: 765-773, 1992.
3. Atar, D., W. D. Gao, and E. Marban. Alterations of excitation-contraction coupling in stunned myocardium and in failing myocardium. J. Mol. Cell. Cardiol. 27: 783-791, 1995.
4. Baker, A. J., R. Brandes, J. H. Schreur, S. A. Camacho, and M. W. Weiner. Protein and acidosis alter calcium-binding and fluorescence spectra of the calcium indicator indo-1. Biophys. J. 67: 1646-1654, 1994.
5. Benzi, R. H., and R. Lerch. Dissociation between contractile function and oxidative metabolism in postisehemic myocardium. Attenuation by ruthenium red administered during reperfusion. Circ. Res. 71. 567-576, 1992.
6. Bolli, R. Mechanism of myocardial "stunning". Circulation 82: 723-738, 1990.
7. Bourdillon, P. D., and P.A. Poole-Wilson. Effects of ischaemia and reperfusion on calcium exchange and mechanical function in isolated rabbit myocardium. Cardiovasc. Res. 15: 121-130, 1981.
8. c in whole perfused hearts using indo-1 fluorometry. Biophys. J. 65: 1973-1982, 1993.
9. c quantitation in perfused hearts. Biophys. J. 65: 1983-1993, 1993.
10. Brandes, R., V. M. Figueredo, S. A. Camacho, B. M. Massie, and M. W. Weiner. Suppression of motion artifacts in fluorescence spectroscopy of perfused hearts. Am. J. Physiol. 263 (Heart Circ. Physiol. 32): H972-H980, 1992.
11. Brandes, R., V. M. Figueredo, S. A. Camacho, and M. W. Weiner. Compensation for changes in tissue light absorption in fluorometry of hypoxic perfused rat hearts. Am. J. Physiol. 266 (Heart Circ. Physiol. 35): H2554-H2567, 1994.
12. 2+ transient decline and myocardial relaxation are slowed during low-flow ischemia in rat hearts. J. Clin. Invest. 93: 951-957, 1994.
13. Carrozza, J. P., Jr., L. A. Bentivegna, C. P. Williams, R. E. Kuntz, W. Grossman, and J. P. Morgan. Decreased myofilament responsiveness in myocardial stunning follows transient calcium overload during ischemia and reperfusion. Circ. Res. 71: 1334-1340, 1992.
14. 2+ in hearts of cardiomyopathic hamsters. Am. J. Physiol. 264 (Heart Circ. Physiol. 33): H2188-H2197, 1993.
15. Ferrari, R., F. di Lisa, R. Raddino, and O. Visioli. The effects of ruthenium red on mitochondrial function during postischaemic reperfusion. J. Mol. Cell. Cardiol. 14: 737-740, 1982.
16. Figueredo, V. M., R. Brandes, M. W. Weiner, B. M. Massie, and S. A. Camacho. Cardiac contractile dysfunction during mild coronary flow reductions is due to an altered calcium-pressure relationship in rat hearts. J. Clin. Invest. 90: 1794-1802, 1992.
17. Figueredo, V. M., R. Brandes, M. W. Weiner, B. M. Massie, and S. A. Camacho. Endocardial versus epicardial differences of intracellular free calcium under normal and ischemic conditions in perfused rat hearts. Circ. Res. 72: 1082-1090, 1993.
18. Figueredo, V. M., K. P. Dresdner, Jr., A. C. Wolney, and A. M. Keller. Postischaemic reperfusion injury in the isolated rat heart: effect of ruthenium red. Cardiovasc. Res. 25: 337-342, 1991.
19. 2+ responsiveness and altered diastolic function in intact ventricular muscle. Circ. Res. 76: 1036-1048, 1995.
20. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260: 3440-3450, 1985.
21. Gupta, M. P., I. R. Innes, and N. S. Dhalla. Responses of contractile function to ruthenium red in rat heart. Am. J. Physiol. 255 (Heart Circ. Physiol. 24): H1413-H1420, 1988.
22. 2+ transport. J. Bioeng. Biomembr. 26: 495-508, 1994.
23. Isenberg, G., S. Han, A. Schiefer, and M. F. Wendt-Gallitelli. Changes in mitochondrial calcium concentration during the cardiac contraction cycle. Cardiovasc. Res. 27: 1800-1809, 1993.
24. 2+ oscillations in single living cells revealed by rhod-2 and laser confocal microscopy (Abstract). Biophys. J. 66: A94, 1994.
25. 2+ transients underlie stunning? Circ. Res. 66: 1268-1276, 1990.
26. Kusuoka, H., and E. Marban. Cellular mechanisms of myocardial stunning. Annu. Rev. Physiol. 54: 243-256, 1992.
27. Lorell, B. H., C. S. Apstein, M. J. Cunningham, F. J. Schoen, E. O. Weinberg, G. A. Peeters, and W. H. Barry. Contribution of endothelial cells to calcium-dependent fluorescence transients in rabbit hearts loaded with indo 1. Circ. Res. 67: 415-425, 1990.
28. Marban, E. Myocardial stunning and hibernation. The physiology behind the colloquialisms. Circulation 83: 681-688, 1991.
29. 2+ modulation during postischemic reperfusion in rat heart. Am. J. Physiol. 268 (Heart Circ. Physiol. 37): H100-H111, 1995.
30. Miyata, H., E. G. Lakatta, M. D. Stern, and H. S. Silverman. Relation of mitochondrial and cytosolic free calcium to cardiac myocyte recovery after exposure to anoxia. Circ. Res. 71: 605-613, 1992.
31. 2+ concentration in living single rat cardiac myocytes. Am. J. Physiol. 261 (Heart Circ. Physiol. 30): H1123-H1134, 1991.
32. Murphy, E., R. Jacob, and M. Lieberman. Cytosolic free calcium in chick heart cells. Its role in cell injury. J. Mol. Cell. Cardiol. 17: 221-231, 1985.
33. Nayler, W. G. Calcium and cell death. Eur. Heart J. 4: 33-41, 1983.
34. Otani, H., H. Tanaka, T. Inoue, M. Umemoto, K. Omoto, K. Tanaka, T. Sato, T. Osako, A. Masuda, A. Nonoyama, and T. Kagawa. In vitro study on contribution of oxidative metabolism of isolated rabbit heart mitochondria to myocardial reperfusion injury. Circ. Res. 55: 168-175, 1984.
35. 2+-chelating agents. J. Mol. Cell. Cardiol. 9: 897-908, 1977.
36. Peng, C. F., J. J. Kane, K. D. Straub, and M. L. Murphy. Improvement of mitochondrial energy production in ischemic myocardium by in vivo infusion of ruthenium red. J. Cardiovasc. Pharmacol. 2: 45-54, 1980.
37. 2+. Biophy. J. 70:2571-2580, 1996.
38. 2+, contraction, and potential in cardiac myocytes. Am. J. Physiol. 258 (Heart Circ. Physiol. 27): H574-H586, 1990.
39. 2+ overload in reperfused ischemic myocardium. Annu. Rev. Physiol. 52: 543-559, 1990.
40. Wendt-Gallitelli, M. F., and G. Isenberg. Total and free myoplasmic calcium during a contraction cycle: x-ray microanalysis in guinea-pig ventricular myocytes. J. Physiol. Lond. 435: 349-372, 1991.
41. Westfall, M. V., and R. J. Solaro. Alterations in myofibrillar function and protein profiles after complete global ischemia in rat hearts. Circ. Res. 70: 302-313, 1992.