Regulatory effects of estriol on T cell migration and cytokine profile: Inhibition of transcription factor NF-κB

Journal of Neuroimmunology

Volumn 124, Issue 1-2, 2002, Pages 106-114

  Zang, Ying C Q ^a   Halder, Jyotsnabaran B ^a   Hong, Jian ^a   Rivera, Victor M ^a   Zhang, Jingwu Z ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Estriol; Multiple sclerosis; NF B; T cells

Indexed keywords

ANTIGEN; CYTOKINE; ESTRIOL; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION FUNCTION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; HUMAN; HUMAN CELL; IMMUNOREGULATION; LYMPHOCYTE MIGRATION; PHENOTYPE; PREGNANCY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ADULT; CASE-CONTROL STUDIES; CELL MOVEMENT; CYTOKINES; DNA-BINDING PROTEINS; ESTRIOL; FEMALE; HUMANS; I-KAPPA B PROTEINS; MALE; MATRIX METALLOPROTEINASE 9; MULTIPLE SCLEROSIS; MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE; MULTIPLE SCLEROSIS, RELAPSING-REMITTING; NF-KAPPA B; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036200198     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(02)00016-4     Document Type: Article

References (31)

1. Pregnancy and multiple sclerosis
2. Immunosuppression by glucocorticoids-inhibition of NF-kB activity throgh induction of IkB synthesis
3. Function and activation of NF-kB in the immune system
4. IL-10 suppresses experimental autoimmune neuritis and down-regulates TH1-type immune responses
5. Low-dose estrogen therapy ameliorates experimental autoimmune encephalomyelitis in two different inbred mouse strains
6. IkB interacts with the nuclear-localization sequences of the subunits of NF-kB - A mechanism for cytoplasmic retention
7. Tumor-necrosis factor and interleukin-1 lead to phosphorylation and loss of IkBα-a mechanism for NF-kB activation
8. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s
9. NF-kappa B activation by tumor necrosis factor and interleukin-1
10. Rate of pregnancy-related relapse in multiple sclerosis
11. Steroid hormone regulation of cytokine secretion by proteolipid protein-specific CD4+ T cell clones isolated from multiple sclerosis patients and normal control subjects
12. Estradiol down-regulates LPS-induced cytokine production and NFkB activation in murine macrophages
13. Effect of estradiol on cytokine secretion by proteolipid protein-specific T cell clones isolated from multiple sclerosis patients and normal control subjects
14. The cytokine profile of MBP-reactive T cells and early lines in multiple sclerosis and healthy controls
15. Experimental autoimmune encephalomyelitis in NF-kB-deficient mice: Roles of NF-kB in the activation and differentiation of autoreactive T cells
16. 17 beta-estradiol inhibits tumor necrosis factor-alpha-induced nuclear factor-kappa B activation by increasing nuclear factor-kappa B p105 level in MCF-7 breast cancer cells
17. Estriol ameliorates autoimmune demyelinating disease: Implications for multiple sclerosis
18. Promoter analysis of the gene encoding the IkBα/MAD-3 inhibitor of NF-kB: Positive regulation by members of the rel/NF-kB family
19. The role of adhesion molecules and proteinases in lymphocyte transendothelial migration
20. Molecular control of immune/inflammatory responses: Interactions between nuclear factor-kB and steroid receptor signaling pathways
21. Treatment of multiple sclerosis with gamma interferon: Exacerbations associated with activation of the immune system
22. Estrogen effects in the myocardium: Inhibition of NF-kappaB DNA binding by estrogen receptor-alpha and -beta
23. An improved in vitro assay to quantitate chemotaxis of rat peripheral blood large granular lymphocytes (LGL)
24. IL-10 inhibits NF-kB/rel nuclear activity in CD3 stimulated human peripheral T lymphocytes
25. Role of transcriptional activation of IkBα in mediation of immunosuppression by glucocorticoids
26. Association between tumor necrosis factor-alpha and disease progression in patients with multiple sclerosis
27. NF-kB activation: The IkB kinase revealed?
28. Chemotaxis of T lymphocytes on extracellular matrix proteins
29. Bidirectional cytokine interactions in the maternal-fetal relationship: Is a successful pregnancy a Th2 phnomenon
30. Aberrant T cell migration toward RANTES and MIP-1a in patients with multiple sclerosis: Over-expression of chemokines receptor CCR5