The time course of cardiac Nf-κB activation and TNF-α secretion by cardiac myocytes after burn injury: Contribution to burn-related cardiac contractile dysfunction

Shock

Volumn 17, Issue 4, 2002, Pages 293-299

  Maass, David L ^a   Hybki, Dixie Peters ^a   White, Jean ^a   Horton, Jureta W ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Cardiac contractile function; Cardiomyocyte secretion of the inflammatory cytokine; Langendorff preparation; Nf b; Rat model of thermal trauma; Tnf ; Transcription factor

Indexed keywords

ACETYLLEUCYL LEUCYL NORLEUCINAL; ACETYLLEUCYL-LEUCYL-NORLEUCINAL; AUTACOID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEUPEPTIN; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; BIOSYNTHESIS; BURN; DRUG EFFECT; GENETICS; HEART; HEART CONTRACTION; HEART DISEASE; HEART MUSCLE; HEMODYNAMICS; IN VITRO STUDY; KINETICS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; BURNS; HEART; HEART DISEASES; HEMODYNAMIC PROCESSES; INFLAMMATION MEDIATORS; KINETICS; LEUPEPTINS; MYOCARDIAL CONTRACTION; MYOCARDIUM; NF-KAPPA B; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036549370     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-200204000-00009     Document Type: Article

References (40)

1. Adams HR, Baxter CR, Parker JL: Contractile function of heart muscle from burned guinea pigs. Circ Shock 9:63-73, 1982.
2. Horton JW, White J, Maass D: Protein kinase C inhibition improves ventricular function after thermal trauma. J Trauma 44(2):254-265, 1998.
3. Bankey P, Prager M, Geldon D, Taylor S, McIntyre K: Acute phase hepatocytes regulate liver sinusoidal cell mediator production. Arch Surg 129:1166-1171, 1994.
4. 23Na NMR study. J Surg Res 69:212-219, 1997.
5. Horton JW, Maass DL, White DJ, Sanders B: Hypertonic saline dextran alters burn-related cytokine synthesis by cardiomyocytes. Am J Physiol 280:H1591-H1601, 2000.
6. Williams JG, Bankey P, Minei JP, McIntyre K, Turbeville T: Burn injury enhances alveolar macrophage endotoxin sensitivity. J Burn Care and Rehab 15:493-498, 1994.
7. Meldrum DR: Tumor necrosis factor in the heart. Am J Physiol 274:R577-R595, 1998.
8. Kapadia S, Lee J, Torre-Amione G, Birdsall HH, Ma TS, Mann DL: Tumor necrosis factor-α gene and protein expression in adult feline myocardium after endotoxin administration. J Clin Invest 96:1042-1052, 1993.
9. Kumar A, Thota V, Dee L, Olson J, Uretz E, Parrillo JE: Tumor necrosis factor-α and interleukin 1β are responsible for in vitro myocardial cell depression induced by human septic shock serum. J Exp Med 183:949-958, 1996.
10. Giroir BP, Johnson JH, Brown T, Allen GI, Beutler B: The tissue distribution of tumor necrosis factor biosynthesis during endotoxemia. J Clin Invest 91: 693-698, 1992.
11. Yokoyama T, Nakano M, Bednarczyk JL: Tumor necrosis factor-α provokes a hypertrophic growth response in adult cardiac myocytes. Circulation 95:1247-1252, 1997.
12. Oral H, Kapadia S, Nakano M, Torre-Amione G, Lee J, Lee-Jackson D, Young JB, Mann DL: Tumor necrosis factor a and the failing human heart. Clin Cardiol 18:S20-S27, 1995.
13. Bryant D, Becker L, Richardson J, Shelton J, Franco F, Peshock R, Thompson M, Giroir BP: Cardiac failure in transgenic mice with myocardial expression of tumor necrosis factor-alpha. Circulation 97:175-183, 1998.
14. Meldrum DR, Shenkar R, Sheridan BC, Cain BS, Abraham E, Harken AH: Hemorrhage activates myocardial NF-κB and increases TNF-α in the heart. J Mol Cell Cardiol 29:2849-2854, 1997.
15. Krown KA, Page MT, Nguyen C, et. al.: Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. J Clin Invest 98:2854-2865, 1996.
16. Lightfoot Jr E, Horton JW, Maass DE, Giroir B: TNF-α induced apoptosis of cardiomyocytes. Shock 13 (Suppl), 2000.
17. Haudek SB, Spenser E, Bryant DD, White DJ, Maass DE, Horton JW, Chen ZJ, Giroir BP: Overexpression of cardiac I-κB prevents endotoxin-induced myocardial dysfunction. Am J Physiol 280:H962-H968, 2001.
18. Caput D, Beutler B, Hartog K, Thayer R, Brown-Shimer SE, Cerami A: Identification of a common nucleotide sequence in the 3′-untranslated region of mRNA molecules specifying inflammatory mediators. Proc Natl Acad Sc. 83: 1670-1674, 1986.
19. Schow SR, Joly A: N-acetyl-leucinyl-leucinyl-norleucinal inhibits lipopolysaccharide-induced NF-κB activation and prevents TNF-α and IL-6 synthesis in vivo. Cell Immun 175:199-202, 1997.
20. Schreiber E, Matthias P, Muller MM, Schaffner W: Rapid detection of octomer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res 17:6419-6424, 1989.
21. Horton JW: Cellular basis for burn-mediated cardiac dysfunction in adult rabbits. Am J Physiol 271:H2615-H2621, 1996.
22. Lum RT, Kerwar SS, Meyer SM, Nelson MG, Schow SR, Shiftman D, Wick MM, Joly A: A new structural class of proteosome inhibitors that prevent NF-κB activation. Biochem Pharmacol 55:1391-1397, 1998.
23. Marks JD, Marks CB, Luce JM: Plasma tumor necrosis factor in patients with septic shock: Mortality rate, incidence of adult respiratory distress syndrome and effects of methylprednisolone administration. Am Rev Respir Dis 141:94-97, 1990.
24. Damas P, Reuter A, Gysen P, Demonty J, Lamy M, Franchimont P: Tumor necrosis factor and interleukin-1 serum levels during severe sepsis in humans. Crit Care Med 17:975-978, 1989.
25. White J, Maass D, Horton JW: Development of acute burn model in adult mice for studies of cardiac function and cardiomyocyte cellular function. Shock 16(2):122-129, 2001.
26. Horton JW, Garcia NM, White DJ, Keffer J: Postburn cardiac contractile function and biochemical markers of postburn cardiac injury. J Am Coll Surg 181: 289-298, 1995.
27. Giroir BP, Horton JW, White DJ, Mclntryre KE, Lin CQ: Inhibition of tumor necrosis factor (TNF-α) prevents myocardial dysfunction during burn shock. Am J Physiol 267:H118-H124, 1994.
28. Elgjo GI, Mathey B, de Figueiredo LFP, Schenarts PJ, Horton JW, Kramer GC: Resuscitation with hypertonic saline dextran improves cardiac function in vivo and ex vivo after burn injury in sheep. Shock 9:375-383, 1998.
29. Horton JW: Bacterial translocation after burn injury: contribution of ischemia and permeability channel. Shock 1:286-290, 1994.
30. Tokyay R, Ziegler ST, Traver DE, Stothert Jr JC, Loick HM, Heggers JP, Herndon DN: Postburn gastrointestinal vasoconstriction increases bacterial and endotoxin translocation. J Appl Physiol 74:1521-1527, 1993.
31. Deitch EA: Intestinal permeability is increased in burn patients shortly after injury. Surgery 107:411-416, 1990.
32. Barnes PJ, Karvin M: Nuclear factor kappa B-a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 336:1066-1071, 1997.
33. Mihm KS, Galter D, Droge W: Modulation of transcription factor NFκB activity by intracellular glutathione levels and by variations of the extracellular cysteine supply. FASEB J 9:246-252, 1995.
34. Horton JW, Mileski WJ, White DJ, Lipsky P: Monoclonal antibody to intercellular adhesion molecule-1 reduces cardiac contractile dysfunction after burn injury in rabbits. J Surg Res 64:49-56, 1996.
35. Horton JW, White DJ: Role of xanthine oxidase and leukocytes in postburn cardiac dysfunction. J Am Coll Surg 181:129-137, 1995.
36. Horton JW, White DJ, Maass D, Haudek S, Hybki DP: Antioxidant vitamin therapy alters burn trauma mediated cardiac NF-κB activation and cardiomyocyte cytokine secretion. J Trauma 50(3):397-408, 2001.
37. 4-induced hepatic injury in mice is associated with inhibition of nuclear factor kappa B binding. Hepatology 22:1474-1481, 1995.
38. Graciano AL, Bryant DD, White DJ, Horton JW, Bowels NE, Giroir BP: Targeted disruption of ICAM-1, P-selectin genes improves cardiac function and survival in TNF-α transgenic mice. Am J Physiol 280:H1464-H1471, 2001
39. Finkel MS, Oddis CV, Jacob TD, Watkins SC, Hattler BG, Simmons RL. Negative inotropic effects of cytokines on the heart mediated by nitric oxide. Science 227:387-389, 1992.
40. Oral H, Dorn GW, Mann DE: Sphingosine mediates the immediate negative inotroic effecs of tumor necrosis factor-α in the adult mammalian cardiac myocyte. J Biol Chem 272:4836-4842, 1997.