Liposomal delivery of heat shock protein 72 into renal tubular cells blocks nuclear factor-κB activation, tumor necrosis factor-α production, and subsequent ischemia-induced apoptosis

Circulation Research

Volumn 92, Issue 3, 2003, Pages 293-299

  Meldrum, Kirstan K ^a   Burnett, Arthur L ^b   Meng, Xianzhong ^c   Misseri, Rosalia ^a   Shaw, Matthew B K ^a   Gearhart, John P ^b   Meldrum, Daniel R ^a  

^a INDIANA UNIVERSITY MEDICAL CENTER   (United States)

^b JOHNS HOPKINS HOSPITAL   (United States)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

Inflammation; Kidney; Reperfusion

Indexed keywords

HEAT SHOCK PROTEIN 72; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOSOME; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; ELECTROPHORETIC MOBILITY; GENE ACTIVATION; GENE INDUCTION; GENE TRANSFER; GENETIC TRANSCRIPTION; HEAT STRESS; IMMUNOCYTOCHEMISTRY; INFLAMMATION; KIDNEY CELL; KIDNEY INJURY; KIDNEY ISCHEMIA; KIDNEY TUBULE CELL; NICK END LABELING; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; PROTEIN TRANSPORT; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; ANTIBODIES; APOPTOSIS; BLOTTING, WESTERN; HEAT; HEAT-SHOCK PROTEINS; HEAT-SHOCK RESPONSE; HSP72 HEAT-SHOCK PROTEINS; HUMANS; I-KAPPA B PROTEINS; ISCHEMIA; KIDNEY TUBULES; LIPOSOMES; LLC-PK1 CELLS; NF-KAPPA B; RNA, MESSENGER; SWINE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0037458926     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000057754.35180.99     Document Type: Article

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