-
3
-
-
0030666222
-
Innate immunity: The virtues of a nonclonal system of recognition
-
Medzhitov, R., and C. A. Janeway, Jr. 1997. Innate immunity: the virtues of a nonclonal system of recognition. Cell 91:295.
-
(1997)
Cell
, vol.91
, pp. 295
-
-
Medzhitov, R.1
Janeway Jr., C.A.2
-
4
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov, R., P. Preston-Hurlburt, and C. A. Janeway, Jr. 1997. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388:394.
-
(1997)
Nature
, vol.388
, pp. 394
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway Jr., C.A.3
-
5
-
-
0031905311
-
A family of human receptors structurally related to Drosophila Toll
-
Rock, F. L., G. Hardiman, J. C. Timans, R. A. Kastelein, and J. F. Bazan. 1998. A family of human receptors structurally related to Drosophila Toll. Proc. Natl. Acad. Sci. USA 95:588.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 588
-
-
Rock, F.L.1
Hardiman, G.2
Timans, J.C.3
Kastelein, R.A.4
Bazan, J.F.5
-
6
-
-
0033614428
-
TLR6: A novel member of an expanding Toll-like receptor family
-
Takeuchi, O., T. Kawai, H. Sanjo, N. G. Copeland, D. J. Gilbert, N. A. Jenkins, K. Takeda, and S. Akira. 1999. TLR6: A novel member of an expanding Toll-like receptor family. Gene. 231:59.
-
(1999)
Gene
, vol.231
, pp. 59
-
-
Takeuchi, O.1
Kawai, T.2
Sanjo, H.3
Copeland, N.G.4
Gilbert, D.J.5
Jenkins, N.A.6
Takeda, K.7
Akira, S.8
-
7
-
-
0034457684
-
Cloning and characterization of a subfamily of human Toll-like receptors: HTLR7, hTLR8 and hTLR9
-
Chuang, T. H., and R. J. Ulevitch. 2000. Cloning and characterization of a subfamily of human Toll-like receptors: hTLR7, hTLR8 and hTLR9. Eur. Cytokine Netw. 11:372.
-
(2000)
Eur. Cytokine Netw.
, vol.11
, pp. 372
-
-
Chuang, T.H.1
Ulevitch, R.J.2
-
8
-
-
0035911644
-
Identification of hTLR10: A novel human Toll-like receptor preferentially expressed in immune cells
-
Chuang, T., and R. J. Ulevitch. 2001. Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells. Biochim. Biophys. Acta 1518:157.
-
(2001)
Biochim. Biophys. Acta
, vol.1518
, pp. 157
-
-
Chuang, T.1
Ulevitch, R.J.2
-
9
-
-
0034456693
-
Three novel mammalian Toll-like receptors: Gene structure, expression, and evolution
-
Du, X., A. Poltorak, Y. Wei, and B. Beutler. 2000. Three novel mammalian Toll-like receptors: gene structure, expression, and evolution. Eur. Cytokine. Netw. 11:362.
-
(2000)
Eur. Cytokine. Netw.
, vol.11
, pp. 362
-
-
Du, X.1
Poltorak, A.2
Wei, Y.3
Beutler, B.4
-
10
-
-
0033580949
-
Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by Toll-like receptor 2
-
Schwandner, R., R. Dziarski, H. Wesche, M. Rothe, and C. J. Kirschning. 1999. Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by Toll-like receptor 2. J. Biol. Chem. 274:17406.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17406
-
-
Schwandner, R.1
Dziarski, R.2
Wesche, H.3
Rothe, M.4
Kirschning, C.J.5
-
11
-
-
0033213590
-
Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components
-
Takeuchi, O., K. Hoshino, T. Kawai, H. Sanjo, H. Takada, T. Ogawa, K. Takeda, and S. Akira. 1999. Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components. Immunity 11:443.
-
(1999)
Immunity
, vol.11
, pp. 443
-
-
Takeuchi, O.1
Hoshino, K.2
Kawai, T.3
Sanjo, H.4
Takada, H.5
Ogawa, T.6
Takeda, K.7
Akira, S.8
-
12
-
-
0033168728
-
Cutting edge: Recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2
-
Yoshimura, A., E. Lien, R. R. Ingalls, E. Tuomanen, R. Dziarski, and D. Golenbock. 1999. Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2. J. Immunol. 163:1.
-
(1999)
J. Immunol.
, vol.163
, pp. 1
-
-
Yoshimura, A.1
Lien, E.2
Ingalls, R.R.3
Tuomanen, E.4
Dziarski, R.5
Golenbock, D.6
-
13
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
-
Alexopoulou, L., A. C. Holt, R. Medzhitov, and R. A. Flavell. 2001. Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3. Nature 413:732.
-
(2001)
Nature
, vol.413
, pp. 732
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
14
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak, A., X. He, I. Smirnova, M. Y. Liu, C. Van Huffel, X. Du, D. Birdwell, E. Alejos, M. Silva, C. Galanos, et al. 1998. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282:2085.
-
(1998)
Science
, vol.282
, pp. 2085
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
Van Huffel, C.5
Du, X.6
Birdwell, D.7
Alejos, E.8
Silva, M.9
Galanos, C.10
-
15
-
-
0033120081
-
Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product
-
Hoshino, K., O. Takeuchi, T. Kawai, H. Sanjo, T. Ogawa, Y. Takeda, K. Takeda, and S. Akira. 1999. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J. Immunol. 162:3749.
-
(1999)
J. Immunol.
, vol.162
, pp. 3749
-
-
Hoshino, K.1
Takeuchi, O.2
Kawai, T.3
Sanjo, H.4
Ogawa, T.5
Takeda, Y.6
Takeda, K.7
Akira, S.8
-
16
-
-
0345561540
-
Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)
-
Qureshi, S. T., L. Lariviere, G. Leveque, S. Clermont, K. J. Moore, P. Gros, and D. Malo. 1999. Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4). J. Exp. Med. 189:615.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 615
-
-
Qureshi, S.T.1
Lariviere, L.2
Leveque, G.3
Clermont, S.4
Moore, K.J.5
Gros, P.6
Malo, D.7
-
17
-
-
0035953543
-
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
-
Hayashi, F., K. D. Smith, A. Ozinsky, T. R. Hawn, E. C. Yi, D. R. Goodlett, J. K. Eng, S. Akira, D. M. Underhill, and A. Aderem. 2001. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature 410:1099.
-
(2001)
Nature
, vol.410
, pp. 1099
-
-
Hayashi, F.1
Smith, K.D.2
Ozinsky, A.3
Hawn, T.R.4
Yi, E.C.5
Goodlett, D.R.6
Eng, J.K.7
Akira, S.8
Underhill, D.M.9
Aderem, A.10
-
18
-
-
1542317550
-
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
-
Diebold, S. S., T. Kaisho, H. Hemmi, S. Akira, and C. Reis e Sousa. 2004. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 303:1529.
-
(2004)
Science
, vol.303
, pp. 1529
-
-
Diebold, S.S.1
Kaisho, T.2
Hemmi, H.3
Akira, S.4
Reis E Sousa, C.5
-
19
-
-
1542317578
-
Species-specific recognition of single-stranded RNA via Toll-like receptor 7 and 8
-
Heil, F., H. Hemmi, H. Hochrein, F. Ampenberger, C. Kirschning, S. Akira, G. Lipford, H. Wagner, and S. Bauer. 2004. Species-specific recognition of single-stranded RNA via Toll-like receptor 7 and 8. Science 303:1526.
-
(2004)
Science
, vol.303
, pp. 1526
-
-
Heil, F.1
Hemmi, H.2
Hochrein, H.3
Ampenberger, F.4
Kirschning, C.5
Akira, S.6
Lipford, G.7
Wagner, H.8
Bauer, S.9
-
20
-
-
1842631428
-
Recognition of single-stranded RNA viruses by Toll-like receptor 7
-
Lund, J. M., L. Alexopoulou, A. Sato, M. Karow, N. C. Adams, N. W. Gale, A. Iwasaki, and R. A. Flavell. 2004. Recognition of single-stranded RNA viruses by Toll-like receptor 7. Proc. Natl. Acad. Sci. USA 101:5598.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 5598
-
-
Lund, J.M.1
Alexopoulou, L.2
Sato, A.3
Karow, M.4
Adams, N.C.5
Gale, N.W.6
Iwasaki, A.7
Flavell, R.A.8
-
21
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi, H., O. Takeuchi, T. Kawai, T. Kaisho, S. Sato, H. Sanjo, M. Matsumoto, K. Hoshino, H. Wagner, K. Takeda, and S. Akira. 2000. A Toll-like receptor recognizes bacterial DNA. Nature 408:740.
-
(2000)
Nature
, vol.408
, pp. 740
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
Kaisho, T.4
Sato, S.5
Sanjo, H.6
Matsumoto, M.7
Hoshino, K.8
Wagner, H.9
Takeda, K.10
Akira, S.11
-
22
-
-
0037114185
-
Cutting edge: A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-β promoter in the Toll-like receptor signaling
-
Yamamoto, M., S. Sato, K. Mori, K. Hoshino, O. Takeuchi, K. Takeda, and S. Akira. 2002. Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-β promoter in the Toll-like receptor signaling. J. Immunol. 169:6668.
-
(2002)
J. Immunol.
, vol.169
, pp. 6668
-
-
Yamamoto, M.1
Sato, S.2
Mori, K.3
Hoshino, K.4
Takeuchi, O.5
Takeda, K.6
Akira, S.7
-
23
-
-
0345991221
-
TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to Toll-like receptor 4 TICAM-1 that induces interferon-β
-
Oshiumi, H., M. Sasai, K. Shida, T. Fujita, M. Matsumoto, and T. Seya. 2003. TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to Toll-like receptor 4 TICAM-1 that induces interferon-β. J. Biol. Chem. 278:49751.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 49751
-
-
Oshiumi, H.1
Sasai, M.2
Shida, K.3
Fujita, T.4
Matsumoto, M.5
Seya, T.6
-
24
-
-
0042591216
-
TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling
-
Bin, L. H., L. G. Xu, and H. B. Shu. 2003. TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling. J. Biol. Chem. 278:24526.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 24526
-
-
Bin, L.H.1
Xu, L.G.2
Shu, H.B.3
-
25
-
-
0242624622
-
TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway
-
Yamamoto, M., S. Sato, H. Hemmi, S. Uematsu, K. Hoshino, T. Kaisho, O. Takeuchi, K. Takeda, and S. Akira. 2003. TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway. Nat. Immunol. 4:1144.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 1144
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Uematsu, S.4
Hoshino, K.5
Kaisho, T.6
Takeuchi, O.7
Takeda, K.8
Akira, S.9
-
26
-
-
0035555301
-
TIRAP: An adapter molecule in the Toll signaling pathway
-
Horng, T., G. M. Barton, and R. Medzhitov. 2001. TIRAP: an adapter molecule in the Toll signaling pathway. Nat. Immunol. 2:835.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 835
-
-
Horng, T.1
Barton, G.M.2
Medzhitov, R.3
-
27
-
-
0141959224
-
LPS-TLR4 signaling to IRF-3/7 and NF-κB involves the Toll adapters TRAM and TRIP
-
Fitzgerald, K. A., D. C. Rowe, B. J. Barnes, D. R. Caffrey, A. Visintin, E. Latz, B. Monks, P. M. Pitha, and D. T. Golenbock. 2003. LPS-TLR4 signaling to IRF-3/7 and NF-κB involves the Toll adapters TRAM and TRIP. J. Exp. Med. 198:1043.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1043
-
-
Fitzgerald, K.A.1
Rowe, D.C.2
Barnes, B.J.3
Caffrey, D.R.4
Visintin, A.5
Latz, E.6
Monks, B.7
Pitha, P.M.8
Golenbock, D.T.9
-
28
-
-
0032133278
-
MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways
-
Medzhitov, R., P. Preston-Hurlburt, E. Kopp, A. Stadlen, C. Chen, S. Ghosh, and C. A. Janeway, Jr. 1998. MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways. Mol. Cell 2:253.
-
(1998)
Mol. Cell
, vol.2
, pp. 253
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Kopp, E.3
Stadlen, A.4
Chen, C.5
Ghosh, S.6
Janeway Jr., C.A.7
-
29
-
-
0037320451
-
TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-β induction
-
Oshiumi, H., M. Matsumoto, K. Funami, T. Akazawa, and T. Seya. 2003. TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-β induction. Nat. Immunol. 4:161.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 161
-
-
Oshiumi, H.1
Matsumoto, M.2
Funami, K.3
Akazawa, T.4
Seya, T.5
-
30
-
-
0035817925
-
Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction
-
Fitzgerald, K. A., E. M. Palsson-McDermott, A. G. Bowie, C. A. Jefferies, A. S. Mansell, G. Brady, E. Brint, A. Dunne, P. Gray, M. T. Harte, et al. 2001. Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature 413:78.
-
(2001)
Nature
, vol.413
, pp. 78
-
-
Fitzgerald, K.A.1
Palsson-McDermott, E.M.2
Bowie, A.G.3
Jefferies, C.A.4
Mansell, A.S.5
Brady, G.6
Brint, E.7
Dunne, A.8
Gray, P.9
Harte, M.T.10
-
31
-
-
0037505362
-
The Toll-IL-1 receptor adaptor family grows to five members
-
O'Neill, L. A., K. A. Fitzgerald, and A. G. Bowie. 2003, The Toll-IL-1 receptor adaptor family grows to five members. Trends Immunol. 24:286.
-
(2003)
Trends Immunol.
, vol.24
, pp. 286
-
-
O'Neill, L.A.1
Fitzgerald, K.A.2
Bowie, A.G.3
-
32
-
-
0035895540
-
Apoptotic molecular machinery: Vastly increased complexity in vertebrates revealed by genome comparisons
-
Aravind, L., V. M. Dixit, and E. V. Koonin. 2001. Apoptotic molecular machinery: vastly increased complexity in vertebrates revealed by genome comparisons. Science 291:1279.
-
(2001)
Science
, vol.291
, pp. 1279
-
-
Aravind, L.1
Dixit, V.M.2
Koonin, E.V.3
-
33
-
-
0346849669
-
Toll-like receptor gene family and TIR-domain adapters in Danio rerio
-
Jault, C., L. Pichon, and J. Chluba. 2004. Toll-like receptor gene family and TIR-domain adapters in Danio rerio. Mol. Immunol. 40:759.
-
(2004)
Mol. Immunol.
, vol.40
, pp. 759
-
-
Jault, C.1
Pichon, L.2
Chluba, J.3
-
34
-
-
0347480221
-
Expression analysis of the Toll-like receptor and TIR domain adaptor families of zebrafish
-
Meijer, A. H., S. F. Gabby Krens, I. A. Medina Rodriguez, S. He, W. Bitter, B. Ewa Snaar-Jagalska, and H. P. Spaink. 2004. Expression analysis of the Toll-like receptor and TIR domain adaptor families of zebrafish. Mol. Immunol. 40:773.
-
(2004)
Mol. Immunol.
, vol.40
, pp. 773
-
-
Meijer, A.H.1
Gabby Krens, S.F.2
Medina Rodriguez, I.A.3
He, S.4
Bitter, W.5
Ewa Snaar-Jagalska, B.6
Spaink, H.P.7
-
35
-
-
0036730113
-
Toll and interleukin-1 receptor (TIR) domain-containing proteins in plants: A genomic perspective
-
Jebanathirajah, J. A., S. Peri, and A. Pandey. 2002. Toll and interleukin-1 receptor (TIR) domain-containing proteins in plants: a genomic perspective. Trends Plant Sci. 7:388.
-
(2002)
Trends Plant Sci.
, vol.7
, pp. 388
-
-
Jebanathirajah, J.A.1
Peri, S.2
Pandey, A.3
-
36
-
-
2442664007
-
TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM
-
Couillault, C., N. Pujol, J. Reboul, L. Sabatier, J. F. Guichou, Y. Kohara, and J. J. Ewbank. 2004. TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM. Nat. Immunol. 5:488
-
(2004)
Nat. Immunol.
, vol.5
, pp. 488
-
-
Couillault, C.1
Pujol, N.2
Reboul, J.3
Sabatier, L.4
Guichou, J.F.5
Kohara, Y.6
Ewbank, J.J.7
-
37
-
-
0035367786
-
A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/β-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans
-
Mink, M., B. Fogelgren, K. Olszewski, P. Maroy, and K. Csiszar. 2001. A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/β-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans. Genomics 74:234.
-
(2001)
Genomics
, vol.74
, pp. 234
-
-
Mink, M.1
Fogelgren, B.2
Olszewski, K.3
Maroy, P.4
Csiszar, K.5
-
39
-
-
0036709969
-
A universal role for MyD88 in TLR/IL-1R-mediated signaling
-
Janssens, S., and R. Beyaert. 2002. A universal role for MyD88 in TLR/IL-1R-mediated signaling. Trends Biochem. Sci. 27:474.
-
(2002)
Trends Biochem. Sci.
, vol.27
, pp. 474
-
-
Janssens, S.1
Beyaert, R.2
-
40
-
-
0037129212
-
Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4
-
Suzuki, N., S. Suzuki, G. S. Duncan, D. G. Millar, T. Wada, C. Mirtsos, H. Takada, A. Wakeham, A. Itie, S. Li, et al. 2002. Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4. Nature 416:750.
-
(2002)
Nature
, vol.416
, pp. 750
-
-
Suzuki, N.1
Suzuki, S.2
Duncan, G.S.3
Millar, D.G.4
Wada, T.5
Mirtsos, C.6
Takada, H.7
Wakeham, A.8
Itie, A.9
Li, S.10
-
41
-
-
0037117543
-
IRAK-4: A novel member of the IRAK family with the properties of an IRAK-kinase
-
Li, S., A. Strelow, E. J. Fontana, and H. Wesche. 2002. IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase. Proc. Natl. Acad. Sci. USA 99:5567.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 5567
-
-
Li, S.1
Strelow, A.2
Fontana, E.J.3
Wesche, H.4
-
42
-
-
0029761275
-
TRAF6 is a signal transducer for interleukin-1
-
Cao, Z., J. Xiong, M. Takeuchi, T. Kurama, and D. V. Goeddel. 1996. TRAF6 is a signal transducer for interleukin-1. Nature 383:443.
-
(1996)
Nature
, vol.383
, pp. 443
-
-
Cao, Z.1
Xiong, J.2
Takeuchi, M.3
Kurama, T.4
Goeddel, D.V.5
-
43
-
-
0029865142
-
IRAK: A kinase associated with the interleukin-1 receptor
-
Cao, Z., W. J. Henzel, and X. Gao. 1996. IRAK: a kinase associated with the interleukin-1 receptor. Science 271:1128.
-
(1996)
Science
, vol.271
, pp. 1128
-
-
Cao, Z.1
Henzel, W.J.2
Gao, X.3
-
44
-
-
0037153191
-
Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4
-
Yamamoto, M., S. Sato, H. Hemmi, H. Sanjo, S. Uematsu, T. Kaisho, K. Hoshino, O. Takeuchi, M. Kobayashi, T. Fujita, et al. 2002. Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4. Nature 420:324.
-
(2002)
Nature
, vol.420
, pp. 324
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Sanjo, H.4
Uematsu, S.5
Kaisho, T.6
Hoshino, K.7
Takeuchi, O.8
Kobayashi, M.9
Fujita, T.10
-
45
-
-
0037153130
-
The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors
-
Horng, T., G. M. Barton, R. A. Flavell, and R. Medzhitov. 2002. The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors. Nature 420:329.
-
(2002)
Nature
, vol.420
, pp. 329
-
-
Horng, T.1
Barton, G.M.2
Flavell, R.A.3
Medzhitov, R.4
-
46
-
-
0042679529
-
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
-
Hoebe, K., X. Du, P. Georgel, E. Janssen, K. Tabeta, S. O. Kim, J. Goode, P. Lin, N. Mann, S. Mudd, et al. 2003. Identification of Lps2 as a key transducer of MyD88-independent TIR signalling. Nature 424:743.
-
(2003)
Nature
, vol.424
, pp. 743
-
-
Hoebe, K.1
Du, X.2
Georgel, P.3
Janssen, E.4
Tabeta, K.5
Kim, S.O.6
Goode, J.7
Lin, P.8
Mann, N.9
Mudd, S.10
-
47
-
-
0043176281
-
Role of adaptor TRIF in the MyD88-independent Toll-like receptor signaling pathway
-
Yamamoto, M., S. Sato, H. Hemmi, K. Hoshino, T. Kaisho, H. Sanjo, O. Takeuchi, M. Sugiyama, M. Okabe, K. Takeda, and S. Akira. 2003. Role of adaptor TRIF in the MyD88-independent Toll-like receptor signaling pathway. Science 301:640.
-
(2003)
Science
, vol.301
, pp. 640
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Hoshino, K.4
Kaisho, T.5
Sanjo, H.6
Takeuchi, O.7
Sugiyama, M.8
Okabe, M.9
Takeda, K.10
Akira, S.11
-
48
-
-
0032015647
-
Virus infection induces the assembly of coordinately activated transcription factors on the IFN-β enhancer in vivo
-
Wathelet, M. G., C. H. Lin, B. S. Parekh, L. V. Ronco, P. M. Howley, and T. Maniatis. 1998. Virus infection induces the assembly of coordinately activated transcription factors on the IFN-β enhancer in vivo. Mol. Cell 1:507.
-
(1998)
Mol. Cell
, vol.1
, pp. 507
-
-
Wathelet, M.G.1
Lin, C.H.2
Parekh, B.S.3
Ronco, L.V.4
Howley, P.M.5
Maniatis, T.6
-
49
-
-
0038393016
-
IKKε and TBK1 are essential components of the IRF3 signaling pathway
-
Fitzgerald, K. A., S. M. McWhirter, K. L. Faia, D. C. Rowe, E. Latz, D. T. Golenbock, A. J. Coyle, S. M. Liao, and T. Maniatis. 2003. IKKε and TBK1 are essential components of the IRF3 signaling pathway. Nat. Immunol. 4:491.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 491
-
-
Fitzgerald, K.A.1
McWhirter, S.M.2
Faia, K.L.3
Rowe, D.C.4
Latz, E.5
Golenbock, D.T.6
Coyle, A.J.7
Liao, S.M.8
Maniatis, T.9
-
50
-
-
0345827590
-
IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts
-
McWhirter, S. M., K. A. Fitzgerald, J. Rosains, D. C. Rowe, D. T. Golenbock, and T. Maniatis. 2004. IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts. Proc. Natl. Acad. Sci. USA 101:233.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 233
-
-
McWhirter, S.M.1
Fitzgerald, K.A.2
Rosains, J.3
Rowe, D.C.4
Golenbock, D.T.5
Maniatis, T.6
-
51
-
-
0038363463
-
Triggering the interferon antiviral response through an IKK-related pathway
-
Sharma, S., B. R. tenOever, N. Grandvaux, G. P. Zhou, R. Lin, and J. Hiscott. 2003. Triggering the interferon antiviral response through an IKK-related pathway. Science 300:1148.
-
(2003)
Science
, vol.300
, pp. 1148
-
-
Sharma, S.1
TenOever, B.R.2
Grandvaux, N.3
Zhou, G.P.4
Lin, R.5
Hiscott, J.6
-
52
-
-
0035889228
-
Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes
-
Kawai, T., O. Takeuchi, T. Fujita, J. Inoue, P. F. Muhlradt, S. Sato, K. Hoshino, and S. Akira. 2001. Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes. J. Immunol. 167:5887.
-
(2001)
J. Immunol.
, vol.167
, pp. 5887
-
-
Kawai, T.1
Takeuchi, O.2
Fujita, T.3
Inoue, J.4
Muhlradt, P.F.5
Sato, S.6
Hoshino, K.7
Akira, S.8
-
53
-
-
0035061538
-
IRF family of transcription factors as regulators of host defense
-
Taniguchi, T., K. Ogasawara, A. Takaoka, and N. Tanaka. 2001. IRF family of transcription factors as regulators of host defense. Annu. Rev. Immunol. 19:623.
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 623
-
-
Taniguchi, T.1
Ogasawara, K.2
Takaoka, A.3
Tanaka, N.4
-
54
-
-
0032915860
-
Structural and functional analysis of interferon regulatory factor 3: Localization of the transactivation and autoinhibitory domains
-
Lin, R., Y. Mamane, and J. Hiscott. 1999. Structural and functional analysis of interferon regulatory factor 3: localization of the transactivation and autoinhibitory domains. Mol. Cell Biol. 19:2465.
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 2465
-
-
Lin, R.1
Mamane, Y.2
Hiscott, J.3
-
55
-
-
0031893220
-
Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation
-
Lin, R., C. Heylbroeck, P. M. Pitha, and J. Hiscott. 1998. Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation. Mol. Cell. Biol. 18:2986.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2986
-
-
Lin, R.1
Heylbroeck, C.2
Pitha, P.M.3
Hiscott, J.4
-
56
-
-
1542723466
-
Toll-like receptor 3-mediated activation of NF-κB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-β
-
Jiang, Z., T. W. Mak, G. Sen, and X. Li. 2004. Toll-like receptor 3-mediated activation of NF-κB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-β. Proc. Natl. Acad. Sci. USA 101:3533.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3533
-
-
Jiang, Z.1
Mak, T.W.2
Sen, G.3
Li, X.4
-
57
-
-
0141923690
-
Toll/IL-1 receptor domain-containing adaptor inducing IFN-β (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-κB and IFN-regulatory factor-3, in the Toll-like receptor signaling
-
Sato, S., M. Sugiyama, M. Yamamoto, Y. Watanabe, T. Kawai, K. Takeda, and S. Akira. 2003. Toll/IL-1 receptor domain-containing adaptor inducing IFN-β (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-κB and IFN-regulatory factor-3, in the Toll-like receptor signaling. J. Immunol. 171:4304.
-
(2003)
J. Immunol.
, vol.171
, pp. 4304
-
-
Sato, S.1
Sugiyama, M.2
Yamamoto, M.3
Watanabe, Y.4
Kawai, T.5
Takeda, K.6
Akira, S.7
-
58
-
-
1642617628
-
The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4
-
Hsu, L. C., J. M. Park, K. Zhang, J. L. Luo, S. Maeda, R. J. Kaufman, L. Eckmann, D. G. Guiney, and M. Karin. 2004. The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4. Nature 428:341.
-
(2004)
Nature
, vol.428
, pp. 341
-
-
Hsu, L.C.1
Park, J.M.2
Zhang, K.3
Luo, J.L.4
Maeda, S.5
Kaufman, R.J.6
Eckmann, L.7
Guiney, D.G.8
Karin, M.9
-
59
-
-
0033618630
-
Cell activation and apoptosis by bacterial lipoproteins through Toll-like receptor-2
-
Aliprantis, A. O., R. B. Yang, M. R. Mark, S. Suggett, B. Devaux, J. D. Radolf, G. R. Klimpel, P. Godowski, and A. Zychlinsky. 1999. Cell activation and apoptosis by bacterial lipoproteins through Toll-like receptor-2. Science 285:736.
-
(1999)
Science
, vol.285
, pp. 736
-
-
Aliprantis, A.O.1
Yang, R.B.2
Mark, M.R.3
Suggett, S.4
Devaux, B.5
Radolf, J.D.6
Klimpel, G.R.7
Godowski, P.8
Zychlinsky, A.9
-
60
-
-
0034601057
-
The apoptotic signaling pathway activated by Toll-like receptor-2
-
Aliprantis, A. O., R. B. Yang, D. S. Weiss, P. Godowski, and A. Zychlinsky. 2000. The apoptotic signaling pathway activated by Toll-like receptor-2. EMBO J. 19:3325.
-
(2000)
EMBO J.
, vol.19
, pp. 3325
-
-
Aliprantis, A.O.1
Yang, R.B.2
Weiss, D.S.3
Godowski, P.4
Zychlinsky, A.5
-
61
-
-
0036172129
-
The Fas-associated death domain protein suppresses activation of NF-κB by LPS and IL-1β
-
Bannerman, D. D., J. C. Tupper, J. D. Kelly, R. K. Winn, and J. M. Harlan. 2002. The Fas-associated death domain protein suppresses activation of NF-κB by LPS and IL-1β. J. Clin. Invest. 109:419.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 419
-
-
Bannerman, D.D.1
Tupper, J.C.2
Kelly, J.D.3
Winn, R.K.4
Harlan, J.M.5
-
62
-
-
0035094982
-
Host defense, viruses and apoptosis
-
Barber, G. N. 2001. Host defense, viruses and apoptosis. Cell Death Differ. 8:113.
-
(2001)
Cell Death Differ.
, vol.8
, pp. 113
-
-
Barber, G.N.1
-
63
-
-
0037833742
-
Caspase-activation pathways in apoptosis and immunity
-
Creagh, E. M., H. Conroy, and S. J. Martin. 2003. Caspase-activation pathways in apoptosis and immunity. Immunol. Rev. 193:10.
-
(2003)
Immunol. Rev.
, vol.193
, pp. 10
-
-
Creagh, E.M.1
Conroy, H.2
Martin, S.J.3
-
64
-
-
0242656497
-
Death receptor-induced cell killing
-
Thorburn, A. 2004. Death receptor-induced cell killing. Cell Signal 16:139.
-
(2004)
Cell Signal
, vol.16
, pp. 139
-
-
Thorburn, A.1
-
65
-
-
0033709108
-
Activation of a caspase-9-mediated apoptotic pathway by subcellular redistribution of the novel caspase recruitment domain protein TMS1
-
McConnell, B. B., and P. M. Vertino. 2000. Activation of a caspase-9-mediated apoptotic pathway by subcellular redistribution of the novel caspase recruitment domain protein TMS1. Cancer Res. 60:6243.
-
(2000)
Cancer Res.
, vol.60
, pp. 6243
-
-
McConnell, B.B.1
Vertino, P.M.2
-
66
-
-
0032482752
-
MEKK1 activates both IκB kinase α and IκB kinase β
-
Lee, F. S., R. T. Peters, L. C. Dang, and T. Maniatis. 1998. MEKK1 activates both IκB kinase α and IκB kinase β. Proc. Natl. Acad. Sci. USA 95:9319.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 9319
-
-
Lee, F.S.1
Peters, R.T.2
Dang, L.C.3
Maniatis, T.4
-
68
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner, M. O. 2000. The biochemistry of apoptosis. Nature 407:770.
-
(2000)
Nature
, vol.407
, pp. 770
-
-
Hengartner, M.O.1
-
69
-
-
0033597882
-
Functional interaction of DFF35 and DFF45 with caspase-activated DNA fragmentation nuclease DFF40
-
Gu, J., R. P. Dong, C. Zhang, D. F. McLaughlin, M. X. Wu, and S. F. Schlossman. 1999. Functional interaction of DFF35 and DFF45 with caspase-activated DNA fragmentation nuclease DFF40. J. Biol. Chem. 274:20759.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 20759
-
-
Gu, J.1
Dong, R.P.2
Zhang, C.3
McLaughlin, D.F.4
Wu, M.X.5
Schlossman, S.F.6
-
70
-
-
0030916417
-
DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
-
Liu, X., H. Zou, C. Slaughter, and X. Wang. 1997. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 89:175.
-
(1997)
Cell
, vol.89
, pp. 175
-
-
Liu, X.1
Zou, H.2
Slaughter, C.3
Wang, X.4
-
71
-
-
0035980091
-
Crystal structure of baculovirus P35 reveals a novel conformational change in the reactive site loop after caspase cleavage
-
dela Cruz, W. P., P. D. Friesen, and A. J. Fisher. 2001. Crystal structure of baculovirus P35 reveals a novel conformational change in the reactive site loop after caspase cleavage. J. Biol. Chem. 276:32933.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 32933
-
-
Dela Cruz, W.P.1
Friesen, P.D.2
Fisher, A.J.3
-
72
-
-
0842281645
-
Cell death: Critical control points
-
Danial, N. N., and S. J. Korsmeyer. 2004. Cell death: critical control points. Cell 116:205.
-
(2004)
Cell
, vol.116
, pp. 205
-
-
Danial, N.N.1
Korsmeyer, S.J.2
-
73
-
-
0032080197
-
Defects in regulation of apoptosis in caspase-2-deficient mice
-
Bergeron, L., G. I. Perez, G. Macdonald, L. Shi, Y. Sun, A. Jurisicova, S. Varmuza, K. E. Latham, J. A. Flaws, I. C. Salter, et al. 1998. Defects in regulation of apoptosis in caspase-2-deficient mice. Genes Dev. 12:1304.
-
(1998)
Genes Dev.
, vol.12
, pp. 1304
-
-
Bergeron, L.1
Perez, G.I.2
Macdonald, G.3
Shi, L.4
Sun, Y.5
Jurisicova, A.6
Varmuza, S.7
Latham, K.E.8
Flaws, J.A.9
Salter, I.C.10
-
74
-
-
0037162833
-
Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization
-
Lassus, P., X. Opitz-Araya, and Y. Lazebnik. 2002. Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization. Science 297:1352.
-
(2002)
Science
, vol.297
, pp. 1352
-
-
Lassus, P.1
Opitz-Araya, X.2
Lazebnik, Y.3
-
75
-
-
2442453730
-
The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress
-
Tinel, A., and J. Tschopp. 2004. The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress. Science 304:843.
-
(2004)
Science
, vol.304
, pp. 843
-
-
Tinel, A.1
Tschopp, J.2
-
76
-
-
2542457495
-
Inflammatory caspases; linking an intracellular innate immune system to autoinflammatory diseases
-
Martinon, F., and J. Tschopp. 2004. Inflammatory caspases; linking an intracellular innate immune system to autoinflammatory diseases. Cell 117:561.
-
(2004)
Cell
, vol.117
, pp. 561
-
-
Martinon, F.1
Tschopp, J.2
-
77
-
-
0035827569
-
Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex
-
Krueger, A., I. Schmitz, S. Baumann, P. H. Krammer, and S. Kirchhoff. 2001. Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex. J. Biol. Chem. 276:20633.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20633
-
-
Krueger, A.1
Schmitz, I.2
Baumann, S.3
Krammer, P.H.4
Kirchhoff, S.5
-
78
-
-
0033941111
-
Viral caspase inhibitors CrmA and p35
-
Zhou, Q., and G. S. Salvesen. 2000. Viral caspase inhibitors CrmA and p35. Methods Enzymol. 322:143.
-
(2000)
Methods Enzymol.
, vol.322
, pp. 143
-
-
Zhou, Q.1
Salvesen, G.S.2
-
80
-
-
0037192790
-
Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X- Linked inhibitor-of-apoptosis protein
-
Sun, X. M., S. B. Bratton, M. Butterworth, M. MacFarlane, and G. M. Cohen. 2002. Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X- linked inhibitor-of-apoptosis protein. J. Biol. Chem. 277:11345.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 11345
-
-
Sun, X.M.1
Bratton, S.B.2
Butterworth, M.3
MacFarlane, M.4
Cohen, G.M.5
-
81
-
-
0036205587
-
Mechanism of caspase activation and inhibition during apoptosis
-
Shi, Y. 2002. Mechanism of caspase activation and inhibition during apoptosis. Molecular Cell 9:459.
-
(2002)
Molecular Cell
, vol.9
, pp. 459
-
-
Shi, Y.1
-
82
-
-
0024516201
-
The involvement of NF-κB in β-interferon gene regulation reveals its role as widely inducible mediator of signal transduction
-
Lenardo, M. J., C. M. Fan, T. Maniatis, and B. D. 1989. The involvement of NF-κB in β-interferon gene regulation reveals its role as widely inducible mediator of signal transduction. Cell 57:287.
-
(1989)
Cell
, vol.57
, pp. 287
-
-
Lenardo, M.J.1
Fan, C.M.2
Maniatis, T.3
-
83
-
-
2442605662
-
Mechanisms of the TRIF-induced interferon-stimulated response element and NF-κB activation and apoptosis pathways
-
Han, K. J., X. Su, L. G. Xu, L. H. Bin, J. Zhang, and H. B. Shu. 2004. Mechanisms of the TRIF-induced interferon-stimulated response element and NF-κB activation and apoptosis pathways. J. Biol. Chem. 279:15652.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 15652
-
-
Han, K.J.1
Su, X.2
Xu, L.G.3
Bin, L.H.4
Zhang, J.5
Shu, H.B.6
-
85
-
-
2442642691
-
RIP1 is an essential mediator of Toll-like receptor 3-induced NF-κB activation
-
Meylan, E., K. Burns, K. Hofmann, V. Blancheteau, F. Martinon, M. Kelliher, and J. Tschopp. 2004. RIP1 is an essential mediator of Toll-like receptor 3-induced NF-κB activation. Nat. Immunol. 5:503.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 503
-
-
Meylan, E.1
Burns, K.2
Hofmann, K.3
Blancheteau, V.4
Martinon, F.5
Kelliher, M.6
Tschopp, J.7
-
86
-
-
0037088632
-
Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3
-
Sun, X., J. Yin, M. A. Starovasnik, W. J. Fairbrother, and V. M. Dixit. 2002. Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3. J. Biol. Chem. 277:9505.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 9505
-
-
Sun, X.1
Yin, J.2
Starovasnik, M.A.3
Fairbrother, W.J.4
Dixit, V.M.5
-
87
-
-
0034025957
-
The IRF-3 transcription factor mediates Sendai virus-induced apoptosis
-
Heylbroeck, C., S. Balachandran, M. J. Servant, C. DeLuca, G. N. Barber, R. Lin, and J. Hiscott. 2000. The IRF-3 transcription factor mediates Sendai virus-induced apoptosis. J. Virol. 74:3781.
-
(2000)
J. Virol.
, vol.74
, pp. 3781
-
-
Heylbroeck, C.1
Balachandran, S.2
Servant, M.J.3
Deluca, C.4
Barber, G.N.5
Lin, R.6
Hiscott, J.7
-
88
-
-
0033725155
-
The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation
-
Devin, A., A. Cook, Y. Lin, Y. Rodriguez, M. Kelliher, and Z. Liu. 2000. The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation. Immunity 12:419.
-
(2000)
Immunity
, vol.12
, pp. 419
-
-
Devin, A.1
Cook, A.2
Lin, Y.3
Rodriguez, Y.4
Kelliher, M.5
Liu, Z.6
-
89
-
-
0033546276
-
RIP3, a novel apoptosis-inducing kinase
-
Sun, X., J. Lee, T. Navas, D. T. Baldwin, T. A. Stewart, and V. M. Dixit. 1999. RIP3, a novel apoptosis-inducing kinase. J. Biol. Chem. 274:16871.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 16871
-
-
Sun, X.1
Lee, J.2
Navas, T.3
Baldwin, D.T.4
Stewart, T.A.5
Dixit, V.M.6
-
90
-
-
0029760732
-
RIP and FADD: Two "death domain"-containing proteins can induce apoptosis by convergent, but dissociable, pathways
-
Grimm, S., B. Z. Stanger, and P. Leder. 1996. RIP and FADD: two "death domain"-containing proteins can induce apoptosis by convergent, but dissociable, pathways. Proc. Natl. Acad Sci. USA 93:10923.
-
(1996)
Proc. Natl. Acad Sci. USA
, vol.93
, pp. 10923
-
-
Grimm, S.1
Stanger, B.Z.2
Leder, P.3
-
91
-
-
0032033132
-
The death domain kinase RIP mediates the TNF-induced NF-κB signal
-
Kelliher, M. A., S. Grimm, Y. Ishida, F. Kuo, B. Z. Stanger, and P. Leder. 1998. The death domain kinase RIP mediates the TNF-induced NF-κB signal. Immunity 8:297.
-
(1998)
Immunity
, vol.8
, pp. 297
-
-
Kelliher, M.A.1
Grimm, S.2
Ishida, Y.3
Kuo, F.4
Stanger, B.Z.5
Leder, P.6
-
92
-
-
0029992609
-
Suppression of TNF-α-induced apoptosis by NF-κB
-
Van Antwerp, D. J., S. J. Martin, T. Kafri, D. R. Green, and I. M. Verma. 1996. Suppression of TNF-α-induced apoptosis by NF-κB. Science 274:787.
-
(1996)
Science
, vol.274
, pp. 787
-
-
Van Antwerp, D.J.1
Martin, S.J.2
Kafri, T.3
Green, D.R.4
Verma, I.M.5
-
93
-
-
0038714270
-
Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFκB and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR
-
Jiang, Z., M. Zamanian-Daryoush, H. Nie, A. M. Silva, B. R. Williams, and X. Li. 2003. Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFκB and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR. J. Biol. Chem. 278:16713.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 16713
-
-
Jiang, Z.1
Zamanian-Daryoush, M.2
Nie, H.3
Silva, A.M.4
Williams, B.R.5
Li, X.6
-
94
-
-
0033587070
-
Identification of RIP3, a RIP-like kinase that activates apoptosis and NFκB
-
Yu, P. W., B. C. Huang, M. Shen, J. Quast, E. Chan, X. Xu, G. P. Nolan, D. G. Payan, and Y. Luo. 1999. Identification of RIP3, a RIP-like kinase that activates apoptosis and NFκB. Curr. Biol. 9:539.
-
(1999)
Curr. Biol.
, vol.9
, pp. 539
-
-
Yu, P.W.1
Huang, B.C.2
Shen, M.3
Quast, J.4
Chan, E.5
Xu, X.6
Nolan, G.P.7
Payan, D.G.8
Luo, Y.9
-
95
-
-
0034485512
-
Critical roles of Toll-like receptors in host defense
-
Kaisho, T., and S. Akira. 2000. Critical roles of Toll-like receptors in host defense. Crit. Rev. Immunol. 20:393.
-
(2000)
Crit. Rev. Immunol.
, vol.20
, pp. 393
-
-
Kaisho, T.1
Akira, S.2
-
96
-
-
0042405132
-
Recognition of microbial infection by Toll-like receptors
-
Kopp, E., and R. Medzhitov. 2003. Recognition of microbial infection by Toll-like receptors. Curr. Opin. Immunol. 15:396.
-
(2003)
Curr. Opin. Immunol.
, vol.15
, pp. 396
-
-
Kopp, E.1
Medzhitov, R.2
-
98
-
-
0346731246
-
How we detect microbes and respond to them: The Toll-like receptors and their transducers
-
Beutler, B., K. Hoebe, X. Du, and R. J. Ulevitch. 2003. How we detect microbes and respond to them: the Toll-like receptors and their transducers. J. Leukocyte. Biol. 74:479.
-
(2003)
J. Leukocyte. Biol.
, vol.74
, pp. 479
-
-
Beutler, B.1
Hoebe, K.2
Du, X.3
Ulevitch, R.J.4
-
99
-
-
0037460116
-
Recognition of pathogen-associated molecular patterns by TLR family
-
Akira, S., and H. Hemmi. 2003. Recognition of pathogen-associated molecular patterns by TLR family. Immunol. Lett. 85:85.
-
(2003)
Immunol. Lett.
, vol.85
, pp. 85
-
-
Akira, S.1
Hemmi, H.2
|