How we detect microbes and respond to them: The Toll-like receptors and their transducers

Journal of Leukocyte Biology

Volumn 74, Issue 4, 2003, Pages 479-485

  Beutler, B ^a   Hoebe, K ^a   Du, X ^a   Ulevitch, R J ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Adjuvant; Infection; Innate immunity; Interferon; Interleukin 1; Lipopolysaccharide; MD 2 molecule; Sepsis; TNF

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; LIGAND; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG;

HOST PATHOGEN INTERACTION; HOST RESISTANCE; HUMAN; IMMUNITY; IMMUNOCOMPETENT CELL; IMMUNOMODULATION; IMMUNOSTIMULATION; INFLAMMATION; INNATE IMMUNITY; METAZOON; MICROORGANISM; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN INDUCTION; REVIEW; SEPSIS; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, DIFFERENTIATION; HUMANS; IMMUNITY, NATURAL; INFECTION; INFLAMMATION; LIPOPOLYSACCHARIDES; MEMBRANE GLYCOPROTEINS; MYELOID DIFFERENTIATION FACTOR 88; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC; SEPSIS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

BACTERIA (MICROORGANISMS); MAMMALIA; METAZOA;

EID: 0346731246     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0203082     Document Type: Review

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