The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4

Nature

Volumn 428, Issue 6980, 2004, Pages 341-345

  Hsu, Li Chung ^a   Park, Jin Mo ^a   Zhang, Kezhong ^c   Luo, Jun Li ^a   Maeda, Shin ^a   Kaufman, Randal J ^c   Eckmann, Lars ^b   Guiney, Donald G ^b   Karin, Michael ^a  

^a San Diego   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CELL CULTURE; IMMUNOLOGY; RNA;

CELL WALLS; PATHOGENS;

ENZYMES;

ANTHRAX TOXIN; BACTERIUM LIPOPOLYSACCHARIDE; BIOLOGICAL FACTOR; DOUBLE STRANDED RNA; INTERFERON RESPONSE FACTOR 3; LIPOTEICHOIC ACID; MITOGEN ACTIVATED PROTEIN KINASE P38; NUCLEIC ACID; PROTEIN KINASE; PROTEIN KINASE R; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; VIRULENCE FACTOR; CELL SURFACE RECEPTOR; DNA BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; IRF3 PROTEIN, MOUSE; LIPOPOLYSACCHARIDE; MEMBRANE PROTEIN; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR;

MEDICINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BACILLUS ANTHRACIS; BACTERIAL CELL WALL; BACTERIAL VIRULENCE; CONTROLLED STUDY; IMMUNE SYSTEM; INNATE IMMUNITY; MACROPHAGE; MICROORGANISM; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; SALMONELLA; SHIGELLA; SIGNAL TRANSDUCTION; YERSINIA; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG EFFECT; GENE DELETION; GENETICS; METABOLISM; MICROBIOLOGY; PHYSIOLOGY; SALMONELLA TYPHIMURIUM; YERSINIA PSEUDOTUBERCULOSIS;

ANIMALIA; ANTHRAX; BACILLUS ANTHRACIS; BACTERIA (MICROORGANISMS); SALMONELLA; SHIGELLA; YERSINIA;

ANIMALS; APOPTOSIS; BACILLUS ANTHRACIS; CELLS, CULTURED; DNA-BINDING PROTEINS; EIF-2 KINASE; GENE DELETION; INTERFERON REGULATORY FACTOR-3; LIPOPOLYSACCHARIDES; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MICE; RECEPTORS, CELL SURFACE; SALMONELLA TYPHIMURIUM; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS; TRANSCRIPTION FACTORS; YERSINIA PSEUDOTUBERCULOSIS;

EID: 1642617628     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature02405     Document Type: Article

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