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Volumn 26, Issue 2, 2005, Pages 283-306

Molecular biology of gonadotropin-releasing hormone (GnRH)-I, GnRH-II, and their receptors in humans

Author keywords

[No Author keywords available]

Indexed keywords

BUSERELIN; CETRORELIX; COMPLEMENTARY DNA; DESLORELIN; G PROTEIN COUPLED RECEPTOR; GONADORELIN; GONADORELIN RECEPTOR; GONADOTROPIN RELEASING HORMONE I; GONADOTROPIN RELEASING HORMONE II; GONADOTROPIN RELEASING HORMONE RECEPTOR TYPE 1; GONADOTROPIN RELEASING HORMONE RECEPTOR TYPE 2; GOSERELIN; LEUPRORELIN; MITOGEN ACTIVATED PROTEIN KINASE; RHODOPSIN; TRIPTORELIN; UNCLASSIFIED DRUG;

EID: 17044397637     PISSN: 0163769X     EISSN: None     Source Type: Journal    
DOI: 10.1210/er.2003-0039     Document Type: Review
Times cited : (255)

References (353)
  • 1
    • 0001169908 scopus 로고
    • Gonadotropin secretion and its control
    • Knobil E, Neill JD, eds. New York: Raven Press
    • Fink G 1988 Gonadotropin secretion and its control. In: Knobil E, Neill JD, eds. The physiology of reproduction. New York: Raven Press; 1349-1377
    • (1988) The Physiology of Reproduction , pp. 1349-1377
    • Fink, G.1
  • 2
    • 0032052309 scopus 로고    scopus 로고
    • Effects of LHRH-analogues on mitogenic signal transduction in cancer cells
    • Emons G, Muller V, Ortmann O, Schulz KD 1998 Effects of LHRH-analogues on mitogenic signal transduction in cancer cells. J Steroid Biochem Mol Biol 65:199-206
    • (1998) J Steroid Biochem Mol Biol , vol.65 , pp. 199-206
    • Emons, G.1    Muller, V.2    Ortmann, O.3    Schulz, K.D.4
  • 3
    • 0035145550 scopus 로고    scopus 로고
    • Comparison of the effects of GnRH-I and GnRH-II on HCG synthesis and secretion by first trimester trophoblast
    • Islami D, Chardonnens D, Campana A, Bischof P 2001 Comparison of the effects of GnRH-I and GnRH-II on HCG synthesis and secretion by first trimester trophoblast. Mol Hum Reprod 7:3-9
    • (2001) Mol Hum Reprod , vol.7 , pp. 3-9
    • Islami, D.1    Chardonnens, D.2    Campana, A.3    Bischof, P.4
  • 4
    • 0035103322 scopus 로고    scopus 로고
    • Stimulation of mitogen-activated protein kinase by gonadotropin-releasing hormone in human granulosa-luteal cells
    • Rang SK, Tai CJ, Nathwani PS, Choi KC, Leung PC 2001 Stimulation of mitogen-activated protein kinase by gonadotropin-releasing hormone in human granulosa-luteal cells. Endocrinology 142:671-679
    • (2001) Endocrinology , vol.142 , pp. 671-679
    • Rang, S.K.1    Tai, C.J.2    Nathwani, P.S.3    Choi, K.C.4    Leung, P.C.5
  • 5
    • 0033977938 scopus 로고    scopus 로고
    • Effects of gonadotropin-releasing hormone agonist on the incidence of apoptosis in porcine and human granulosa cells
    • Zhao S, Saito H, Wang X, Saito T, Kaneko T, Hiroi M 2000 Effects of gonadotropin-releasing hormone agonist on the incidence of apoptosis in porcine and human granulosa cells. Gynecol Obstet Invest 49:52-56
    • (2000) Gynecol Obstet Invest , vol.49 , pp. 52-56
    • Zhao, S.1    Saito, H.2    Wang, X.3    Saito, T.4    Kaneko, T.5    Hiroi, M.6
  • 6
    • 0036924522 scopus 로고    scopus 로고
    • Effects of GnRH analogues, 'add-back' steroid therapy, antiestrogen and antiprogestins on leiomyoma and myometrial smooth muscle cell growth and transforming growth factor-β expression
    • Chegini N, Ma C, Tang XM, Williams RS 2002 Effects of GnRH analogues, 'add-back' steroid therapy, antiestrogen and antiprogestins on leiomyoma and myometrial smooth muscle cell growth and transforming growth factor-β expression. Mol Hum Reprod 8:1071-1078
    • (2002) Mol Hum Reprod , vol.8 , pp. 1071-1078
    • Chegini, N.1    Ma, C.2    Tang, X.M.3    Williams, R.S.4
  • 7
    • 0036912911 scopus 로고    scopus 로고
    • The neuropeptides GnRH-II and GnRH-I are produced by human T cells and trigger laminin receptor gene expression, adhesion, chemotaxis and homing to specific organs
    • Chen A, Ganor Y, Rahimipour S, Ben-Aroya N, Koch Y, Levite M 2002 The neuropeptides GnRH-II and GnRH-I are produced by human T cells and trigger laminin receptor gene expression, adhesion, chemotaxis and homing to specific organs. Nat Med 8:1421-1426
    • (2002) Nat Med , vol.8 , pp. 1421-1426
    • Chen, A.1    Ganor, Y.2    Rahimipour, S.3    Ben-Aroya, N.4    Koch, Y.5    Levite, M.6
  • 8
    • 0042384384 scopus 로고    scopus 로고
    • Differential effects of gonadotropin-releasing hormone I and II on the urokinase-type plasminogen activator/plasminogen activator inhibitor system in human decidual stromal cells in vitro
    • Chou CS, MacCalman CD, Leung PC 2003 Differential effects of gonadotropin-releasing hormone I and II on the urokinase-type plasminogen activator/plasminogen activator inhibitor system in human decidual stromal cells in vitro. J Clin Endocrinol Metab 88:3806-3815
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 3806-3815
    • Chou, C.S.1    MacCalman, C.D.2    Leung, P.C.3
  • 9
    • 0037328743 scopus 로고    scopus 로고
    • Dose-dependent effects of gonadotropin-releasing hormone on matrix metalloproteinase (MMP)-2, and MMP-9 and tissue specific inhibitor of metalloproteinases-1 messenger ribonucleic acid levels in human decidual stromal cells in vitro
    • Chou CS, Tai CJ, MacCalman CD, Leung PC 2003 Dose-dependent effects of gonadotropin-releasing hormone on matrix metalloproteinase (MMP)-2, and MMP-9 and tissue specific inhibitor of metalloproteinases-1 messenger ribonucleic acid levels in human decidual stromal cells in vitro. J Clin Endocrinol Metab 88:680-688
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 680-688
    • Chou, C.S.1    Tai, C.J.2    MacCalman, C.D.3    Leung, P.C.4
  • 10
    • 0037323435 scopus 로고    scopus 로고
    • Tumor necrosis factor-α-induced interleukin-8 (IL-8) expression in endometriotic stromal cells, probably through nuclear factor-κB activation: Gonadotropin-releasing hormone agonist treatment reduced IL-8 expression
    • Sakamoto Y, Harada T, Hone S, Iba Y, Taniguchi F, Yoshida S, Iwabe T, Terakawa N 2003 Tumor necrosis factor-α-induced interleukin-8 (IL-8) expression in endometriotic stromal cells, probably through nuclear factor-κB activation: gonadotropin-releasing hormone agonist treatment reduced IL-8 expression. J Clin Endocrinol Metab 88:730-735
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 730-735
    • Sakamoto, Y.1    Harada, T.2    Hone, S.3    Iba, Y.4    Taniguchi, F.5    Yoshida, S.6    Iwabe, T.7    Terakawa, N.8
  • 11
    • 0028306250 scopus 로고
    • Gonadotropin-releasing hormone and its analogs
    • Conn PM, Crowley Jr WF 1994 Gonadotropin-releasing hormone and its analogs. Annu Rev Med 45:391-405
    • (1994) Annu Rev Med , vol.45 , pp. 391-405
    • Conn, P.M.1    Crowley Jr., W.F.2
  • 13
    • 0037315907 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone and reproductive medicine
    • Shalev E, Leung PC 2003 Gonadotropin-releasing hormone and reproductive medicine. J Obstet Gynaecol Can 25:98-113
    • (2003) J Obstet Gynaecol Can , vol.25 , pp. 98-113
    • Shalev, E.1    Leung, P.C.2
  • 14
    • 0037012226 scopus 로고    scopus 로고
    • Evolutionary development of three gonadotropin-releasing hormone (GnRH) systems in vertebrates
    • Dubois EA, Zandbergen MA, Peute J, Goos HJ 2002 Evolutionary development of three gonadotropin-releasing hormone (GnRH) systems in vertebrates. Brain Res Bull 57:413-418
    • (2002) Brain Res Bull , vol.57 , pp. 413-418
    • Dubois, E.A.1    Zandbergen, M.A.2    Peute, J.3    Goos, H.J.4
  • 15
    • 0011305311 scopus 로고
    • Identification of the second gonadotropin-releasing hormone in chicken hypothalamus: Evidence that gonadotropin secretion is probably controlled by two distinct gonadotropin-releasing hormone in avian species
    • Miyamoto K, Hasegawa Y, Nomura M, Igarashi M, Kangawa K, Matsuo H 1984 Identification of the second gonadotropin-releasing hormone in chicken hypothalamus: evidence that gonadotropin secretion is probably controlled by two distinct gonadotropin-releasing hormone in avian species. Proc Natl Acad Sci USA 81: 3874-3878
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 3874-3878
    • Miyamoto, K.1    Hasegawa, Y.2    Nomura, M.3    Igarashi, M.4    Kangawa, K.5    Matsuo, H.6
  • 17
    • 0038069320 scopus 로고    scopus 로고
    • GnRH II and type II GnRH receptors
    • Millar RP 2003 GnRH II and type II GnRH receptors. Trends Endocrinol Metab 14:35-43
    • (2003) Trends Endocrinol Metab , vol.14 , pp. 35-43
    • Millar, R.P.1
  • 18
    • 0037227498 scopus 로고    scopus 로고
    • An evolutionarily conserved form of gonadotropin-releasing hormone coordinates energy and reproductive behavior
    • Temple JL, Millar RP, Rissman EF 2003 An evolutionarily conserved form of gonadotropin-releasing hormone coordinates energy and reproductive behavior. Endocrinology 144:13-19
    • (2003) Endocrinology , vol.144 , pp. 13-19
    • Temple, J.L.1    Millar, R.P.2    Rissman, E.F.3
  • 19
    • 0034740086 scopus 로고    scopus 로고
    • Expression and antiproliferative effect of a second form of gonadotropin-releasing hormone in normal and neoplastic ovarian surface epithelial cells
    • Choi KC, Auersperg N, Leung PC 2001 Expression and antiproliferative effect of a second form of gonadotropin-releasing hormone in normal and neoplastic ovarian surface epithelial cells. J Clin Endocrinol Metab 86:5075-5078
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5075-5078
    • Choi, K.C.1    Auersperg, N.2    Leung, P.C.3
  • 20
    • 0035114414 scopus 로고    scopus 로고
    • Differential regulation of two forms of gonadotropin-releasing hormone messenger ribonucleic acid in human granulosa-luteal cells
    • Kang SK, Tai CJ, Nathwani PS, Leung PC 2001 Differential regulation of two forms of gonadotropin-releasing hormone messenger ribonucleic acid in human granulosa-luteal cells. Endocrinology 142:182-192
    • (2001) Endocrinology , vol.142 , pp. 182-192
    • Kang, S.K.1    Tai, C.J.2    Nathwani, P.S.3    Leung, P.C.4
  • 21
    • 0036965115 scopus 로고    scopus 로고
    • Expression of gonadotropin-releasing hormone II (GnRH-II) receptor in human endometrial and ovarian cells and effects of GnRH-II on tumor cell proliferation
    • Grundker C, Gunthert AR, Millar RP, Emons G 2002 Expression of gonadotropin-releasing hormone II (GnRH-II) receptor in human endometrial and ovarian cells and effects of GnRH-II on tumor cell proliferation. J Clin Endocrinol Metab 87:1427-1430
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 1427-1430
    • Grundker, C.1    Gunthert, A.R.2    Millar, R.P.3    Emons, G.4
  • 22
    • 0036928768 scopus 로고    scopus 로고
    • The effects of gonadotropin-releasing hormone (GnRH) I and GnRH II on the urokinase-type plasminogen activator/plasminogen activator inhibitor system in human extravillous cytotrophoblasts in vitro
    • Chou CS, Zhu H, Shalev E, MacCalman CD, Leung PC 2002 The effects of gonadotropin-releasing hormone (GnRH) I and GnRH II on the urokinase-type plasminogen activator/plasminogen activator inhibitor system in human extravillous cytotrophoblasts in vitro. J Clin Endocrinol Metab 87:5594-5603
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 5594-5603
    • Chou, C.S.1    Zhu, H.2    Shalev, E.3    MacCalman, C.D.4    Leung, P.C.5
  • 23
    • 0242288694 scopus 로고    scopus 로고
    • Regulatory effects of gonadotropin-releasing hormone (GnRH) I and GnRH II on the levels of matrix metalloproteinase (MMP)-2, MMP-9, and tissue inhibitor of metalloproteinases-1 in primary cultures of human extravillous cytotrophoblasts
    • Chou CS, Zhu H, MacCalman CD, Leung PC 2003 Regulatory effects of gonadotropin-releasing hormone (GnRH) I and GnRH II on the levels of matrix metalloproteinase (MMP)-2, MMP-9, and tissue inhibitor of metalloproteinases-1 in primary cultures of human extravillous cytotrophoblasts. J Clin Endocrinol Metab 88: 4781-4790
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 4781-4790
    • Chou, C.S.1    Zhu, H.2    MacCalman, C.D.3    Leung, P.C.4
  • 24
    • 0022610758 scopus 로고
    • Isolation of the gene and hypothalamic cDNA for the common precursor of gonadotropin-releasing hormone and prolactin release-inhibiting factor in human and rat
    • Adelman JP, Mason AJ, Hayflick JS, Seeburg PH 1986 Isolation of the gene and hypothalamic cDNA for the common precursor of gonadotropin-releasing hormone and prolactin release-inhibiting factor in human and rat. Proc Natl Acad Sci USA 83:179-183
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 179-183
    • Adelman, J.P.1    Mason, A.J.2    Hayflick, J.S.3    Seeburg, P.H.4
  • 25
    • 0021209195 scopus 로고
    • Characterization of cDNA for precursor of human luteinizing hormone releasing hormone
    • Seeburg PH, Adelman JP 1984 Characterization of cDNA for precursor of human luteinizing hormone releasing hormone. Nature 311:666-668
    • (1984) Nature , vol.311 , pp. 666-668
    • Seeburg, P.H.1    Adelman, J.P.2
  • 26
    • 0025319890 scopus 로고
    • Isolation and characterization of the human gonadotropin-releasing hormone gene in the hypothalamus and placenta
    • Radovick S, Wondisford FE, Nakayama Y, Yamada M, Cutler GB, Weintraub BD 1990 Isolation and characterization of the human gonadotropin-releasing hormone gene in the hypothalamus and placenta. Mol Endocrinol 4:476-480
    • (1990) Mol Endocrinol , vol.4 , pp. 476-480
    • Radovick, S.1    Wondisford, F.E.2    Nakayama, Y.3    Yamada, M.4    Cutler, G.B.5    Weintraub, B.D.6
  • 27
    • 0022644792 scopus 로고
    • Human luteinizing hormone-releasing hormone gene (LHRH) is located on short arm of chromosome 8 (region8p11.2-p21)
    • Yang-Feng TL, Seeburg PH, Francke U 1986 Human luteinizing hormone-releasing hormone gene (LHRH) is located on short arm of chromosome 8 (region8p11.2-p21). Somat Cell Mol Genet 12: 95-100
    • (1986) Somat Cell Mol Genet , vol.12 , pp. 95-100
    • Yang-Feng, T.L.1    Seeburg, P.H.2    Francke, U.3
  • 28
    • 0030270621 scopus 로고    scopus 로고
    • Characterization of two new preproGnRH mRNAs in the tree shrew: First direct evidence for mesencephalic GnRH gene expression in a placental mammal
    • Kasten TL, White SA, Norton TT, Bond CT, Adelman KP, Fernald RD 1996 Characterization of two new preproGnRH mRNAs in the tree shrew: first direct evidence for mesencephalic GnRH gene expression in a placental mammal. Gen Comp Endocrinol 104:7-19
    • (1996) Gen Comp Endocrinol , vol.104 , pp. 7-19
    • Kasten, T.L.1    White, S.A.2    Norton, T.T.3    Bond, C.T.4    Adelman, K.P.5    Fernald, R.D.6
  • 29
    • 0025836522 scopus 로고
    • Computer-assisted mapping of immunoreactive mammalian gonadotropin-releasing hormone in adult human basal forebrain and amygdala
    • Stopa EG, Koh ET, Svendsen CN, Rogers WT, Schwaber JS, King JC 1991 Computer-assisted mapping of immunoreactive mammalian gonadotropin-releasing hormone in adult human basal forebrain and amygdala. Endocrinology 128:3199-3207
    • (1991) Endocrinology , vol.128 , pp. 3199-3207
    • Stopa, E.G.1    Koh, E.T.2    Svendsen, C.N.3    Rogers, W.T.4    Schwaber, J.S.5    King, J.C.6
  • 30
    • 0021298482 scopus 로고
    • Immunocytochemical localization of LHRH in the median eminence, infundibular stalk, and neurohypophysis. Evidence for multiple sites of releasing hormone secretion in humans and other mammals
    • Anthony EL, King JC, Stopa EG 1984 Immunocytochemical localization of LHRH in the median eminence, infundibular stalk, and neurohypophysis. Evidence for multiple sites of releasing hormone secretion in humans and other mammals. Cell Tissue Res 236:5-14
    • (1984) Cell Tissue Res , vol.236 , pp. 5-14
    • Anthony, E.L.1    King, J.C.2    Stopa, E.G.3
  • 31
    • 0021267757 scopus 로고
    • LHRH neurons and their projections in humans and other mammals: Species comparisons
    • King JC, Anthony EL 1984 LHRH neurons and their projections in humans and other mammals: species comparisons. Peptides 5:195-207
    • (1984) Peptides , vol.5 , pp. 195-207
    • King, J.C.1    Anthony, E.L.2
  • 32
    • 0030029162 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone messenger RNA expression in gonadotroph tumors and normal human pituitary
    • Miller GM, Alexander JM, Klibanski A 1996 Gonadotropin-releasing hormone messenger RNA expression in gonadotroph tumors and normal human pituitary. J Clin Endocrinol Metab 81:80-83
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 80-83
    • Miller, G.M.1    Alexander, J.M.2    Klibanski, A.3
  • 33
    • 0031156848 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone and gonadotropin-releasing hormone receptor messenger ribonucleic acids expression in nontumorous and neoplastic pituitaries
    • Sanno N, Jin L, Qian X, Osamura RY, Scheithauer BW, Kovacs K, Lloyd RV 1997 Gonadotropin-releasing hormone and gonadotropin-releasing hormone receptor messenger ribonucleic acids expression in nontumorous and neoplastic pituitaries. J Clin Endocrinol Metab 82:1974-1982
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 1974-1982
    • Sanno, N.1    Jin, L.2    Qian, X.3    Osamura, R.Y.4    Scheithauer, B.W.5    Kovacs, K.6    Lloyd, R.V.7
  • 34
    • 0032544747 scopus 로고    scopus 로고
    • A second isoform of gonadotropin-releasing hormone is present in the brain of human and rodents
    • Chen A, Yahalom D, Ben-Aroya N, Kaganovsky E, Okon E, Koch Y 1998 A second isoform of gonadotropin-releasing hormone is present in the brain of human and rodents. FEBS Lett 435:199-203
    • (1998) FEBS Lett , vol.435 , pp. 199-203
    • Chen, A.1    Yahalom, D.2    Ben-Aroya, N.3    Kaganovsky, E.4    Okon, E.5    Koch, Y.6
  • 36
    • 0018308731 scopus 로고
    • Extrahypothalamic luteinizing hormone-releasing factor (LRF): Release of immunoreactive LRF in vitro
    • Siler-Khodr TM, Khodr GS 1979 Extrahypothalamic luteinizing hormone-releasing factor (LRF): release of immunoreactive LRF in vitro. Fertil Steril 32:294-296
    • (1979) Fertil Steril , vol.32 , pp. 294-296
    • Siler-Khodr, T.M.1    Khodr, G.S.2
  • 37
    • 0018903488 scopus 로고
    • Placental luteinizing hormone-releasing factor and its synthesis
    • Khodr GS, Siler-Khodr TM 1980 Placental luteinizing hormone-releasing factor and its synthesis. Science 207:315-317
    • (1980) Science , vol.207 , pp. 315-317
    • Khodr, G.S.1    Siler-Khodr, T.M.2
  • 38
  • 39
    • 1642336425 scopus 로고    scopus 로고
    • Cellular localization of gonadotropin-releasing hormone (GnRH) I and GnRH II in first-trimester human placenta and deciduas
    • Chou CS, Beristain AG, MacCalman CD, Leung PC 2004 Cellular localization of gonadotropin-releasing hormone (GnRH) I and GnRH II in first-trimester human placenta and deciduas. J Clin Endocrinol Metab 89:1459-1466
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 1459-1466
    • Chou, C.S.1    Beristain, A.G.2    MacCalman, C.D.3    Leung, P.C.4
  • 40
    • 0027968591 scopus 로고
    • Expression of luteinizing hormone releasing hormone and its mRNA in human endometrial cancer cell lines
    • Inner G, Burger C, Ortmann O, Schulz KD, Emons G 1994 Expression of luteinizing hormone releasing hormone and its mRNA in human endometrial cancer cell lines. J Clin Endocrinol Metab 79:916-919
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 916-919
    • Inner, G.1    Burger, C.2    Ortmann, O.3    Schulz, K.D.4    Emons, G.5
  • 41
    • 0029920507 scopus 로고    scopus 로고
    • The expression of gonadotropin-releasing hormone and its receptor in endometrial cancer, and its relevance as an autocrine growth factor
    • Chatzaki E, Bax CM, Eidne KA, Anderson L, Grudzinskas JG, Gallagher CJ 1996 The expression of gonadotropin-releasing hormone and its receptor in endometrial cancer, and its relevance as an autocrine growth factor. Cancer Res 56:2059-2065
    • (1996) Cancer Res , vol.56 , pp. 2059-2065
    • Chatzaki, E.1    Bax, C.M.2    Eidne, K.A.3    Anderson, L.4    Grudzinskas, J.G.5    Gallagher, C.J.6
  • 42
    • 0029823957 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone (GnRH) and GnRH receptor gene expression in human myometrium and leiomyomata and the direct action of GnRH analogs on myometrial smooth muscle cells and interaction with ovarian steroids in vitro
    • Chegini N, Rong H, Dou Q, Kipersztok S, Williams RS 1996 Gonadotropin-releasing hormone (GnRH) and GnRH receptor gene expression in human myometrium and leiomyomata and the direct action of GnRH analogs on myometrial smooth muscle cells and interaction with ovarian steroids in vitro. J Clin Endocrinol Metab 81:3215-3221
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3215-3221
    • Chegini, N.1    Rong, H.2    Dou, Q.3    Kipersztok, S.4    Williams, R.S.5
  • 43
    • 0031063029 scopus 로고    scopus 로고
    • Effects of GnRH analogue on human smooth muscle cells cultured from normal myometrial and from uterine leiomyomal tissues
    • Kobayashi Y, Zhai YL, Iinuma M, Horiuchi A, Nikaido T, Fujii S 1997 Effects of GnRH analogue on human smooth muscle cells cultured from normal myometrial and from uterine leiomyomal tissues. Mol Hum Reprod 3:91-99
    • (1997) Mol Hum Reprod , vol.3 , pp. 91-99
    • Kobayashi, Y.1    Zhai, Y.L.2    Iinuma, M.3    Horiuchi, A.4    Nikaido, T.5    Fujii, S.6
  • 44
    • 0343522721 scopus 로고    scopus 로고
    • Expression of gonadotropin-releasing hormone (GnRH) gene in human uterine endometrial tissue
    • Dong KW, Marcelin K, Hsu MI, Chiang CM, Hoffman G, Roberts JL 1998 Expression of gonadotropin-releasing hormone (GnRH) gene in human uterine endometrial tissue. Mol Hum Reprod 4:893-898
    • (1998) Mol Hum Reprod , vol.4 , pp. 893-898
    • Dong, K.W.1    Marcelin, K.2    Hsu, M.I.3    Chiang, C.M.4    Hoffman, G.5    Roberts, J.L.6
  • 45
    • 0031828974 scopus 로고    scopus 로고
    • Quantitative gonadotropin-releasing hormone gene expression and immunohistochemical localization in human endometrium throughout the menstrual cycle
    • Raga F, Casan EM, Krussel JS, Wen Y, Huang HY, Nezhat C, Polan ML 1998 Quantitative gonadotropin-releasing hormone gene expression and immunohistochemical localization in human endometrium throughout the menstrual cycle. Biol Reprod 59:661-669
    • (1998) Biol Reprod , vol.59 , pp. 661-669
    • Raga, F.1    Casan, E.M.2    Krussel, J.S.3    Wen, Y.4    Huang, H.Y.5    Nezhat, C.6    Polan, M.L.7
  • 46
    • 0035004022 scopus 로고    scopus 로고
    • Expression of the second isoform of gonadotropin-releasing hormone (GnRH-II) in human endometrium throughout the menstrual cycle
    • Cheon KW, Lee HS, Parhar IS, Kang IS 2001 Expression of the second isoform of gonadotropin-releasing hormone (GnRH-II) in human endometrium throughout the menstrual cycle. Mol Hum Reprod 7:447-452
    • (2001) Mol Hum Reprod , vol.7 , pp. 447-452
    • Cheon, K.W.1    Lee, H.S.2    Parhar, I.S.3    Kang, I.S.4
  • 47
    • 0034487528 scopus 로고    scopus 로고
    • Autocrine role of gonadotropin-releasing hormone and its receptor in ovarian cancer cell growth
    • Kang SK, Cheng KW, Nathwani PS, Choi KC, Leung PC 2000 Autocrine role of gonadotropin-releasing hormone and its receptor in ovarian cancer cell growth. Endocrine 13:297-304
    • (2000) Endocrine , vol.13 , pp. 297-304
    • Kang, S.K.1    Cheng, K.W.2    Nathwani, P.S.3    Choi, K.C.4    Leung, P.C.5
  • 48
    • 0034463904 scopus 로고    scopus 로고
    • Role of gonadotropin-releasing hormone as an autocrine growth factor in human ovarian surface epithelium
    • Kang SK, Choi KC, Cheng KW, Nathwani PS, Auersperg N, Leung PC 2000 Role of gonadotropin-releasing hormone as an autocrine growth factor in human ovarian surface epithelium. Endocrinology 141:72-80
    • (2000) Endocrinology , vol.141 , pp. 72-80
    • Kang, S.K.1    Choi, K.C.2    Cheng, K.W.3    Nathwani, P.S.4    Auersperg, N.5    Leung, P.C.6
  • 49
    • 0034456330 scopus 로고    scopus 로고
    • Human oviduct gonadotropin-releasing hormone: Possible implications in fertilization, early embryonic development, and implantation
    • Casan EM, Raga F, Bonilla-Musoles F, Polan ML 2000 Human oviduct gonadotropin-releasing hormone: possible implications in fertilization, early embryonic development, and implantation. J Clin Endocrinol Metab 85:1377-1380
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 1377-1380
    • Casan, E.M.1    Raga, F.2    Bonilla-Musoles, F.3    Polan, M.L.4
  • 50
    • 0025856681 scopus 로고
    • Gonadotropin-releasing hormone gene expression in MDA-MB-231 and ZR-75-1 breast carcinoma cell lines
    • Harris N, Dutlow C, Eidne K, Dong KW, Roberts J, Millar R 1991 Gonadotropin-releasing hormone gene expression in MDA-MB-231 and ZR-75-1 breast carcinoma cell lines. Cancer Res 51:2577-2581
    • (1991) Cancer Res , vol.51 , pp. 2577-2581
    • Harris, N.1    Dutlow, C.2    Eidne, K.3    Dong, K.W.4    Roberts, J.5    Millar, R.6
  • 51
    • 0036173838 scopus 로고    scopus 로고
    • Two forms of gonadotropin-releasing hormone (GnRH) are expressed in human breast tissue and overexpressed in breast cancer: A putative mechanism for the antiproliferative effect of GnRH by down-regulation of acidic ribosomal phosphoproteins P1 and P2
    • Chen A, Kaganovsky E, Rahimipour S, Ben-Aroya N, Okon E, Koch Y 2002 Two forms of gonadotropin-releasing hormone (GnRH) are expressed in human breast tissue and overexpressed in breast cancer: a putative mechanism for the antiproliferative effect of GnRH by down-regulation of acidic ribosomal phosphoproteins P1 and P2. Cancer Res 62:1036-1044
    • (2002) Cancer Res , vol.62 , pp. 1036-1044
    • Chen, A.1    Kaganovsky, E.2    Rahimipour, S.3    Ben-Aroya, N.4    Okon, E.5    Koch, Y.6
  • 53
    • 0033015566 scopus 로고    scopus 로고
    • Human peripheral blood mononuclear cells express gonadotropin-releasing hormone (GnRH), GnRH receptor, and interleukin-2 receptor γ-chain messenger ribonucleic acids that are regulated by GnRH in vitro
    • Chen HF, Jeung EB, Stephenson M, Leung PC 1999 Human peripheral blood mononuclear cells express gonadotropin-releasing hormone (GnRH), GnRH receptor, and interleukin-2 receptor γ-chain messenger ribonucleic acids that are regulated by GnRH in vitro. J Clin Endocrinol Metab 84:743-750
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 743-750
    • Chen, H.F.1    Jeung, E.B.2    Stephenson, M.3    Leung, P.C.4
  • 54
    • 0028787711 scopus 로고
    • Stage specific identification of the expression of GnRH mRNA and localization of the GnRH receptor in mature rat and adult human testis
    • Bahk JY, Hyun JS, Chung SH, Lee H, Kim MO, Lee BH, Choi WS 1995 Stage specific identification of the expression of GnRH mRNA and localization of the GnRH receptor in mature rat and adult human testis. J Urol 154:1958-1961
    • (1995) J Urol , vol.154 , pp. 1958-1961
    • Bahk, J.Y.1    Hyun, J.S.2    Chung, S.H.3    Lee, H.4    Kim, M.O.5    Lee, B.H.6    Choi, W.S.7
  • 55
    • 0033045103 scopus 로고    scopus 로고
    • GnRH mRNA and protein expression in human preimplantation embryos
    • Casan EM, Raga F, Polan ML 1999 GnRH mRNA and protein expression in human preimplantation embryos. Mol Hum Reprod 5:234-239
    • (1999) Mol Hum Reprod , vol.5 , pp. 234-239
    • Casan, E.M.1    Raga, F.2    Polan, M.L.3
  • 56
    • 0030664268 scopus 로고    scopus 로고
    • Evidence for autocrine inhibition of gonadotropin-releasing hormone (GnRH) gene transcription by GnRH in hypothalamic GT1-1 neuronal cells
    • Cho S, Han J, Sun W, Choi D, Kwon HB, Jarry H, Wuttke W, Kim K 1997 Evidence for autocrine inhibition of gonadotropin-releasing hormone (GnRH) gene transcription by GnRH in hypothalamic GT1-1 neuronal cells. Brain Res Mol Brain Res 50:51-58
    • (1997) Brain Res Mol Brain Res , vol.50 , pp. 51-58
    • Cho, S.1    Han, J.2    Sun, W.3    Choi, D.4    Kwon, H.B.5    Jarry, H.6    Wuttke, W.7    Kim, K.8
  • 57
    • 0033038980 scopus 로고    scopus 로고
    • Negative regulation of gonadotropin-releasing hormone and gonadotropin-releasing hormone receptor gene expression by a gonadotropin-releasing hormone agonist in the rat hypothalamus
    • Han YG, Kang SS, Seong JY, Geum D, Suh YH, Kim K 1999 Negative regulation of gonadotropin-releasing hormone and gonadotropin-releasing hormone receptor gene expression by a gonadotropin-releasing hormone agonist in the rat hypothalamus. J Neuroendocrinol 11:195-201
    • (1999) J Neuroendocrinol , vol.11 , pp. 195-201
    • Han, Y.G.1    Kang, S.S.2    Seong, J.Y.3    Geum, D.4    Suh, Y.H.5    Kim, K.6
  • 58
    • 0034455307 scopus 로고    scopus 로고
    • Regulation of gonadotropin-releasing hormone and its receptor gene expression by 17β-estradiol in cultured human granulosaluteal cells
    • Nathwani PS, Kang SK, Cheng KW, Choi KC, Leung PC 2000 Regulation of gonadotropin-releasing hormone and its receptor gene expression by 17β-estradiol in cultured human granulosaluteal cells. Endocrinology 141:1754-1763
    • (2000) Endocrinology , vol.141 , pp. 1754-1763
    • Nathwani, P.S.1    Kang, S.K.2    Cheng, K.W.3    Choi, K.C.4    Leung, P.C.5
  • 59
    • 0035099655 scopus 로고    scopus 로고
    • Estradiol regulates gonadotropin-releasing hormone (GnRH) and its receptor gene expression and antagonizes the growth inhibitory effects of GnRH in human ovarian surface epithelial and ovarian cancer cells
    • Kang SK, Choi KC, Tai CJ, Auersperg N, Leung PC 2001 Estradiol regulates gonadotropin-releasing hormone (GnRH) and its receptor gene expression and antagonizes the growth inhibitory effects of GnRH in human ovarian surface epithelial and ovarian cancer cells. Endocrinology 142:580-588
    • (2001) Endocrinology , vol.142 , pp. 580-588
    • Kang, S.K.1    Choi, K.C.2    Tai, C.J.3    Auersperg, N.4    Leung, P.C.5
  • 60
    • 0036193917 scopus 로고    scopus 로고
    • The transcription of the hGnRH-I and hGnRH-II genes in human neuronal cells is differentially regulated by estrogen
    • Chen A, Ziv K, Laskar-Levy O, Koch Y 2002 The transcription of the hGnRH-I and hGnRH-II genes in human neuronal cells is differentially regulated by estrogen. J Mol Neurosci 18:67-76
    • (2002) J Mol Neurosci , vol.18 , pp. 67-76
    • Chen, A.1    Ziv, K.2    Laskar-Levy, O.3    Koch, Y.4
  • 61
    • 0037328595 scopus 로고    scopus 로고
    • Differential regulation of gonadotropin-releasing hormone (GnRH)I and GnRHII messenger ribonucleic acid by gonadal steroids in human granulosa-luteal cells
    • Khosravi S, Leung PC 2003 Differential regulation of gonadotropin- releasing hormone (GnRH)I and GnRHII messenger ribonucleic acid by gonadal steroids in human granulosa-luteal cells. J Clin Endocrinol Metab 88:663-672
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 663-672
    • Khosravi, S.1    Leung, P.C.2
  • 62
    • 0032746919 scopus 로고    scopus 로고
    • Estrogen receptor-mediated repression of gonadotropin-releasing hormone (GnRH) promoter activity in transfected CHO-K1 cells
    • Chen ZG, Yu KL, Zheng HM, Dong KW 1999 Estrogen receptor-mediated repression of gonadotropin-releasing hormone (GnRH) promoter activity in transfected CHO-K1 cells. Mol Cell Endocrinol 158:131-142
    • (1999) Mol Cell Endocrinol , vol.158 , pp. 131-142
    • Chen, Z.G.1    Yu, K.L.2    Zheng, H.M.3    Dong, K.W.4
  • 63
    • 0033237619 scopus 로고    scopus 로고
    • Estrogen directly represses gonadotropin-releasing hormone (GnRH) gene expression in estrogen receptor-α (ERα)- and ERβ-expressing GT1-7 GnRH neurons
    • Roy D, Angelini NL, Belsham DD 1999 Estrogen directly represses gonadotropin-releasing hormone (GnRH) gene expression in estrogen receptor-α (ERα)- and ERβ-expressing GT1-7 GnRH neurons. Endocrinology 140:5045-5053
    • (1999) Endocrinology , vol.140 , pp. 5045-5053
    • Roy, D.1    Angelini, N.L.2    Belsham, D.D.3
  • 64
    • 0031738481 scopus 로고    scopus 로고
    • Regulation of gonadotropin-releasing hormone (GnRH) gene expression by 5α-dihydrotestosterone in GnRH-secreting GT1-7 hypothalamic neurons
    • Belsham DD, Evangelou A, Roy D, Due VL, Brown TJ 1998 Regulation of gonadotropin-releasing hormone (GnRH) gene expression by 5α- dihydrotestosterone in GnRH-secreting GT1-7 hypothalamic neurons. Endocrinology 139:1108-1114
    • (1998) Endocrinology , vol.139 , pp. 1108-1114
    • Belsham, D.D.1    Evangelou, A.2    Roy, D.3    Due, V.L.4    Brown, T.J.5
  • 65
    • 0036842223 scopus 로고    scopus 로고
    • Differential regulation of gonadotropin-releasing hormone secretion and gene expression by androgen: Membrane versus nuclear receptor activation
    • Shakil T, Hoque AN, Husain M, Belsham DD 2002 Differential regulation of gonadotropin-releasing hormone secretion and gene expression by androgen: membrane versus nuclear receptor activation. Mol Endocrinol 16:2592-2602
    • (2002) Mol Endocrinol , vol.16 , pp. 2592-2602
    • Shakil, T.1    Hoque, A.N.2    Husain, M.3    Belsham, D.D.4
  • 66
    • 0034917627 scopus 로고    scopus 로고
    • Transcriptional regulation of the human GnRH II gene is mediated by a putative cAMP response element
    • Chen A, Laskar-Levy O, Ben-Aroya N, Koch Y 2001 Transcriptional regulation of the human GnRH II gene is mediated by a putative cAMP response element. Endocrinology 142:3483-3492
    • (2001) Endocrinology , vol.142 , pp. 3483-3492
    • Chen, A.1    Laskar-Levy, O.2    Ben-Aroya, N.3    Koch, Y.4
  • 67
    • 0037289712 scopus 로고    scopus 로고
    • Interleukin-1β regulation of gonadotropin-releasing hormone messenger ribonucleic acid in cultured human endometrial stromal cells
    • Huang HY, Raga F, Wen Y, Kruessel JS, Soong YK, Polan ML 2003 Interleukin-1β regulation of gonadotropin-releasing hormone messenger ribonucleic acid in cultured human endometrial stromal cells. Fertil Steril 79:399-406
    • (2003) Fertil Steril , vol.79 , pp. 399-406
    • Huang, H.Y.1    Raga, F.2    Wen, Y.3    Kruessel, J.S.4    Soong, Y.K.5    Polan, M.L.6
  • 68
    • 0031011236 scopus 로고    scopus 로고
    • Regulation of gonadotropin-releasing hormone (GnRH) gene expression by insulin-like growth factor I in a cultured GnRH-expressing neuronal cell line
    • Zhen S, Zakaria M, Wolfe A, Radovick S 1997 Regulation of gonadotropin-releasing hormone (GnRH) gene expression by insulin-like growth factor I in a cultured GnRH-expressing neuronal cell line. Mol Endocrinol 11:1145-1155
    • (1997) Mol Endocrinol , vol.11 , pp. 1145-1155
    • Zhen, S.1    Zakaria, M.2    Wolfe, A.3    Radovick, S.4
  • 70
    • 0024554568 scopus 로고
    • Origin of luteinizing hormone-releasing hormone neurons
    • Schwanzel-Fukuda M, Pfaff DW 1989 Origin of luteinizing hormone-releasing hormone neurons. Nature 338:161-164
    • (1989) Nature , vol.338 , pp. 161-164
    • Schwanzel-Fukuda, M.1    Pfaff, D.W.2
  • 71
    • 0000678016 scopus 로고
    • Evidence that cells expressing luteinizing hormone-releasing hormone mRNA in the mouse are derived from progenitor cells in the olfactory placode
    • Wray S, Grant P, Gainer H 1989 Evidence that cells expressing luteinizing hormone-releasing hormone mRNA in the mouse are derived from progenitor cells in the olfactory placode. Proc Natl Acad Sci USA 86:8132-8136
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 8132-8136
    • Wray, S.1    Grant, P.2    Gainer, H.3
  • 72
    • 0034752124 scopus 로고    scopus 로고
    • Cyclical regulation of GnRH gene expression in GT1-7 GnRH-secreting neurons by melatonin
    • Roy D, Angelini NL, Fujieda H, Brown GM, Belsham DD 2001 Cyclical regulation of GnRH gene expression in GT1-7 GnRH-secreting neurons by melatonin. Endocrinology 142:4711-4720
    • (2001) Endocrinology , vol.142 , pp. 4711-4720
    • Roy, D.1    Angelini, N.L.2    Fujieda, H.3    Brown, G.M.4    Belsham, D.D.5
  • 73
    • 0037016713 scopus 로고    scopus 로고
    • Melatonin receptor activation regulates GnRH gene expression and secretion in GT1-7 GnRH neurons. Signal transduction mechanisms
    • Roy D, Belsham DD 2002 Melatonin receptor activation regulates GnRH gene expression and secretion in GT1-7 GnRH neurons. Signal transduction mechanisms. J Biol Chem 277:251-258
    • (2002) J Biol Chem , vol.277 , pp. 251-258
    • Roy, D.1    Belsham, D.D.2
  • 74
    • 0036186171 scopus 로고    scopus 로고
    • Identification of a discrete promoter region of the human GnRH gene that is sufficient for directing neuron-specific expression: A role for POU homeodomain transcription factors
    • Wolfe A, Kim HH, Tobet S, Stafford DJ, Radovick S 2002 Identification of a discrete promoter region of the human GnRH gene that is sufficient for directing neuron-specific expression: a role for POU homeodomain transcription factors. Mol Endocrinol 16:435-449
    • (2002) Mol Endocrinol , vol.16 , pp. 435-449
    • Wolfe, A.1    Kim, H.H.2    Tobet, S.3    Stafford, D.J.4    Radovick, S.5
  • 75
    • 0038649067 scopus 로고    scopus 로고
    • Functional cooperation between multiple regulatory elements in the untranslated exon 1 stimulates the basal transcription of the human GnRH-II gene
    • Cheng CK, Hoo RL, Chow BK, Leung PC 2003 Functional cooperation between multiple regulatory elements in the untranslated exon 1 stimulates the basal transcription of the human GnRH-II gene. Mol Endocrinol 17:1175-1191
    • (2003) Mol Endocrinol , vol.17 , pp. 1175-1191
    • Cheng, C.K.1    Hoo, R.L.2    Chow, B.K.3    Leung, P.C.4
  • 76
    • 0025052367 scopus 로고
    • Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity
    • Hu YF, Luscher B, Admon A, Mermod N, Tjian R 1990 Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity. Genes Dev 4:1741-1752
    • (1990) Genes Dev , vol.4 , pp. 1741-1752
    • Hu, Y.F.1    Luscher, B.2    Admon, A.3    Mermod, N.4    Tjian, R.5
  • 77
    • 0028092770 scopus 로고
    • Gonadotropin-releasing hormone receptors: Structure and signal transduction pathways
    • Stojilkovic SS, Reinhart J, Catt KJ 1994 Gonadotropin-releasing hormone receptors: structure and signal transduction pathways. Endocr Rev 15:462-499
    • (1994) Endocr Rev , vol.15 , pp. 462-499
    • Stojilkovic, S.S.1    Reinhart, J.2    Catt, K.J.3
  • 78
    • 0030937284 scopus 로고    scopus 로고
    • Molecular mechanism of ligand interaction with gonadotropin-releasing hormone receptor
    • Sealfon SC, Weinstein H, Millar RP 1997 Molecular mechanism of ligand interaction with gonadotropin-releasing hormone receptor. Endocr Rev 18:180-205
    • (1997) Endocr Rev , vol.18 , pp. 180-205
    • Sealfon, S.C.1    Weinstein, H.2    Millar, R.P.3
  • 80
    • 0037862083 scopus 로고    scopus 로고
    • The 'magic tail' of G protein-coupled receptors: An anchorage for functional protein networks
    • Bockaert J, Marin P, Dumuis A, Fagni L 2003 The 'magic tail' of G protein-coupled receptors: an anchorage for functional protein networks. FEBS Lett 546:65-72
    • (2003) FEBS Lett , vol.546 , pp. 65-72
    • Bockaert, J.1    Marin, P.2    Dumuis, A.3    Fagni, L.4
  • 81
    • 0035101820 scopus 로고    scopus 로고
    • Evolving concepts in G protein-coupled receptor endocytosis: The role in receptor desensitization and signaling
    • Ferguson SS 2001 Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. Pharmacol Rev 53:1-24
    • (2001) Pharmacol Rev , vol.53 , pp. 1-24
    • Ferguson, S.S.1
  • 82
    • 0032079392 scopus 로고    scopus 로고
    • Alanine-261 in intracellular loop III of the human gonadotropin-releasing hormone receptor is crucial for G-protein coupling and receptor internalization
    • Myburgh DB, Millar RP, Hapgood JP 1998 Alanine-261 in intracellular loop III of the human gonadotropin-releasing hormone receptor is crucial for G-protein coupling and receptor internalization. Biochem J 331:893-896
    • (1998) Biochem J , vol.331 , pp. 893-896
    • Myburgh, D.B.1    Millar, R.P.2    Hapgood, J.P.3
  • 84
    • 0029666304 scopus 로고    scopus 로고
    • Asn102 of the gonadotropin-releasing hormone receptor is a critical determinant of potency for agonists containing C-terminal glycinamide
    • Davidson JS, McArdle CA, Davies P, Elario R, Flanagan CA, Millar RP 1996 Asn102 of the gonadotropin-releasing hormone receptor is a critical determinant of potency for agonists containing C-terminal glycinamide. J Biol Chem 271:15510-15514
    • (1996) J Biol Chem , vol.271 , pp. 15510-15514
    • Davidson, J.S.1    McArdle, C.A.2    Davies, P.3    Elario, R.4    Flanagan, C.A.5    Millar, R.P.6
  • 86
    • 0034464661 scopus 로고    scopus 로고
    • Residues within transmembrane helices 2 and 5 of the human gonadotropin-releasing hormone receptor contribute to agonist and antagonist binding
    • Hoffmann SH, ter Laak T, Kuhne R, Reilander H, Beckers T 2000 Residues within transmembrane helices 2 and 5 of the human gonadotropin-releasing hormone receptor contribute to agonist and antagonist binding. Mol Endocrinol 14:1099-1115
    • (2000) Mol Endocrinol , vol.14 , pp. 1099-1115
    • Hoffmann, S.H.1    Ter Laak, T.2    Kuhne, R.3    Reilander, H.4    Beckers, T.5
  • 87
    • 0034747357 scopus 로고    scopus 로고
    • Roles of aspartate7.32(302) of the human gonadotropin-releasing hormone receptor in stabilizing a high-affinity ligand conformation
    • Fromme BJ, Katz AA, Roeske RW, Millar RP, Flanagan CA 2001 Roles of aspartate7.32(302) of the human gonadotropin-releasing hormone receptor in stabilizing a high-affinity ligand conformation. Mol Pharmacol 60:1280-1287
    • (2001) Mol Pharmacol , vol.60 , pp. 1280-1287
    • Fromme, B.J.1    Katz, A.A.2    Roeske, R.W.3    Millar, R.P.4    Flanagan, C.A.5
  • 88
    • 0033304628 scopus 로고    scopus 로고
    • Influence of a species-specific extracellular amino acid on expression and function of the human gonadotropin-releasing hormone receptor
    • Arora KK, Chung HO, Catt KJ 1999 Influence of a species-specific extracellular amino acid on expression and function of the human gonadotropin-releasing hormone receptor. Mol Endocrinol 13:890-896
    • (1999) Mol Endocrinol , vol.13 , pp. 890-896
    • Arora, K.K.1    Chung, H.O.2    Catt, K.J.3
  • 89
    • 0025864962 scopus 로고
    • Retroposons-seed of evolution
    • Brosius J 1991 Retroposons-seed of evolution. Science 251:753
    • (1991) Science , vol.251 , pp. 753
    • Brosius, J.1
  • 90
    • 0028861803 scopus 로고
    • The human gonadotropin-releasing hormone receptor gene: Complete structure including multiple promoters, transcription initiation sites, and polyadenylation signals
    • Fan NC, Peng C, Krisinger J, Leung PC 1995 The human gonadotropin- releasing hormone receptor gene: complete structure including multiple promoters, transcription initiation sites, and polyadenylation signals. Mol Cell Endocrinol 107:R1-R8
    • (1995) Mol Cell Endocrinol , vol.107
    • Fan, N.C.1    Peng, C.2    Krisinger, J.3    Leung, P.C.4
  • 91
    • 0030758094 scopus 로고    scopus 로고
    • Molecular structure of the human gonadotropin-releasing hormone receptor gene
    • Kakar SS 1997 Molecular structure of the human gonadotropin-releasing hormone receptor gene. Eur J Endocrinol 137:183-192
    • (1997) Eur J Endocrinol , vol.137 , pp. 183-192
    • Kakar, S.S.1
  • 92
    • 0028036664 scopus 로고
    • Isolation and characterization of the 5′-flanking region of the mouse gonadotropin-releasing hormone receptor gene
    • Albarracin CT, Kaiser UB, Chin WW 1994 Isolation and characterization of the 5′-flanking region of the mouse gonadotropin-releasing hormone receptor gene. Endocrinology 135:2300-2306
    • (1994) Endocrinology , vol.135 , pp. 2300-2306
    • Albarracin, C.T.1    Kaiser, U.B.2    Chin, W.W.3
  • 93
    • 0029965981 scopus 로고    scopus 로고
    • The gene encoding the ovine gonadotropin-releasing hormone (GnRH) receptor: Cloning and initial characterization
    • Campion CE, Turzillo AM, Clay CM 1996 The gene encoding the ovine gonadotropin-releasing hormone (GnRH) receptor: cloning and initial characterization. Gene 170:277-280
    • (1996) Gene , vol.170 , pp. 277-280
    • Campion, C.E.1    Turzillo, A.M.2    Clay, C.M.3
  • 94
    • 0030805547 scopus 로고    scopus 로고
    • Structural organization and characterization of the promoter region of the rat gonadotropin-releasing hormone receptor gene
    • Reinhart J, Xiao S, Arora KK, Catt KJ 1997 Structural organization and characterization of the promoter region of the rat gonadotropin-releasing hormone receptor gene. Mol Cell Endocrinol 130: 1-12
    • (1997) Mol Cell Endocrinol , vol.130 , pp. 1-12
    • Reinhart, J.1    Xiao, S.2    Arora, K.K.3    Catt, K.J.4
  • 95
    • 0029286471 scopus 로고
    • Mapping of the gonadotropin-releasing hormone (GnRH) receptor gene to human chromosome 4q21.2 by fluorescence in situ hybridization
    • Leung PC, Squire J, Peng C, Fan N, Hayden MR, Olofsson JI 1995 Mapping of the gonadotropin-releasing hormone (GnRH) receptor gene to human chromosome 4q21.2 by fluorescence in situ hybridization. Mamm Genome 6:309-310
    • (1995) Mamm Genome , vol.6 , pp. 309-310
    • Leung, P.C.1    Squire, J.2    Peng, C.3    Fan, N.4    Hayden, M.R.5    Olofsson, J.I.6
  • 96
    • 0029988881 scopus 로고    scopus 로고
    • Control of messenger RNA instability in higher eukaryotes
    • Ross J 1996 Control of messenger RNA instability in higher eukaryotes. Trends Genet 12:171-175
    • (1996) Trends Genet , vol.12 , pp. 171-175
    • Ross, J.1
  • 97
    • 0034684980 scopus 로고    scopus 로고
    • AUUUA sequences compromise human insulin-like growth factor binding protein-1 mRNA instability
    • Gay E, Babajko S 2000 AUUUA sequences compromise human insulin-like growth factor binding protein-1 mRNA instability. Biochem Biophys Res Commun 267:509-515
    • (2000) Biochem Biophys Res Commun , vol.267 , pp. 509-515
    • Gay, E.1    Babajko, S.2
  • 98
    • 0030967202 scopus 로고    scopus 로고
    • Characterization of the human thrombopoietin gene promoter. A possible role of an Ets transcription factor, E4TF1/GABP
    • Kamura T, Handa H, Hamasaki N, Kitajima S 1997 Characterization of the human thrombopoietin gene promoter. A possible role of an Ets transcription factor, E4TF1/GABP. J Biol Chem 272: 11361-11368
    • (1997) J Biol Chem , vol.272 , pp. 11361-11368
    • Kamura, T.1    Handa, H.2    Hamasaki, N.3    Kitajima, S.4
  • 99
    • 0030742986 scopus 로고    scopus 로고
    • Structure of the m1 muscarinic acetylcholine receptor gene and its promoter
    • Pepitoni S, Wood IC, Buckley NJ 1997 Structure of the m1 muscarinic acetylcholine receptor gene and its promoter. J Biol Chem 272:17112-17117
    • (1997) J Biol Chem , vol.272 , pp. 17112-17117
    • Pepitoni, S.1    Wood, I.C.2    Buckley, N.J.3
  • 100
    • 0030693993 scopus 로고    scopus 로고
    • Molecular cloning, sequencing and functional study of the promoter region of the human α2C4-adrenergic receptor gene
    • Schaak S, Devedjian JC, Cayla C, Sender Y, Paris H 1997 Molecular cloning, sequencing and functional study of the promoter region of the human α2C4-adrenergic receptor gene. Biochem J 328:431-438
    • (1997) Biochem J , vol.328 , pp. 431-438
    • Schaak, S.1    Devedjian, J.C.2    Cayla, C.3    Sender, Y.4    Paris, H.5
  • 101
    • 0033610058 scopus 로고    scopus 로고
    • Characterization of the promoter region of the human melanocortin-1 receptor (MC1R) gene
    • Moro O, Ideta R, Ifuku O 1999 Characterization of the promoter region of the human melanocortin-1 receptor (MC1R) gene. Biochem Biophys Res Commun 262:452-460
    • (1999) Biochem Biophys Res Commun , vol.262 , pp. 452-460
    • Moro, O.1    Ideta, R.2    Ifuku, O.3
  • 103
    • 0031446639 scopus 로고    scopus 로고
    • Inhibition of gonadotropin-releasing hormone receptor signaling by expression of a splice variant of the human receptor
    • Grosse R, Schoneberg T, Schultz G, Gudermann T 1997 Inhibition of gonadotropin-releasing hormone receptor signaling by expression of a splice variant of the human receptor. Mol Endocrinol 11:1305-1318
    • (1997) Mol Endocrinol , vol.11 , pp. 1305-1318
    • Grosse, R.1    Schoneberg, T.2    Schultz, G.3    Gudermann, T.4
  • 105
    • 0033833895 scopus 로고    scopus 로고
    • Detection of gonadotropin-releasing hormone receptor in normal human pituitary cells and pituitary adenomas using immunohistochemistry
    • La Rosa S, Celato N, Uccella S, Capella C 2000 Detection of gonadotropin-releasing hormone receptor in normal human pituitary cells and pituitary adenomas using immunohistochemistry. Virchows Arch 437:264-269
    • (2000) Virchows Arch , vol.437 , pp. 264-269
    • La Rosa, S.1    Celato, N.2    Uccella, S.3    Capella, C.4
  • 106
    • 0028795235 scopus 로고
    • Expression of human gonadotropin-releasing hormone receptor gene in the placenta and its functional relationship to human chorionic gonadotropin secretion
    • Lin LS, Roberts VJ, Yen SS 1995 Expression of human gonadotropin- releasing hormone receptor gene in the placenta and its functional relationship to human chorionic gonadotropin secretion. J Clin Endocrinol Metab 80:580-585
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 580-585
    • Lin, L.S.1    Roberts, V.J.2    Yen, S.S.3
  • 107
    • 0034456399 scopus 로고    scopus 로고
    • Regulation of human gonadotropin-releasing hormone receptor gene expression in placental cells
    • Cheng KW, Nathwani PS, Leung PC 2000 Regulation of human gonadotropin-releasing hormone receptor gene expression in placental cells. Endocrinology 141:2340-2349
    • (2000) Endocrinology , vol.141 , pp. 2340-2349
    • Cheng, K.W.1    Nathwani, P.S.2    Leung, P.C.3
  • 108
    • 0023180470 scopus 로고
    • Specific binding sites for gonadotropin-releasing hormone, LH/chorionic gonadotropin, low-density lipoprotein, prolactin and FSH in homogenates of human corpus luteum. II. Concentrations throughout the luteal phase of the menstrual cycle and early pregnancy
    • Bramley TA, Stirling D, Swanston IA, Menzies GS, McNeilly AS, Baird DT 1987 Specific binding sites for gonadotropin-releasing hormone, LH/chorionic gonadotropin, low-density lipoprotein, prolactin and FSH in homogenates of human corpus luteum. II. Concentrations throughout the luteal phase of the menstrual cycle and early pregnancy. J Endocrinol 113:317-327
    • (1987) J Endocrinol , vol.113 , pp. 317-327
    • Bramley, T.A.1    Stirling, D.2    Swanston, I.A.3    Menzies, G.S.4    McNeilly, A.S.5    Baird, D.T.6
  • 111
    • 0030955750 scopus 로고    scopus 로고
    • Specific gonadotropin-releasing hormone analogue binding predominantly in human luteinized follicular aspirates and not in human pre-ovulatory follicles
    • Brus L, Lambalk CB, de Koning J, Helder MN, Janssens RM, Schoemaker J 1997 Specific gonadotropin-releasing hormone analogue binding predominantly in human luteinized follicular aspirates and not in human pre-ovulatory follicles. Hum Reprod 12:769-773
    • (1997) Hum Reprod , vol.12 , pp. 769-773
    • Brus, L.1    Lambalk, C.B.2    De Koning, J.3    Helder, M.N.4    Janssens, R.M.5    Schoemaker, J.6
  • 112
    • 0028586112 scopus 로고
    • The nucleotide sequences of human GnRH receptors in breast and ovarian tumors are identical with that found in pituitary
    • Kakar SS, Grizzle WE, Neill JD 1994 The nucleotide sequences of human GnRH receptors in breast and ovarian tumors are identical with that found in pituitary. Mol Cell Endocrinol 106:145-149
    • (1994) Mol Cell Endocrinol , vol.106 , pp. 145-149
    • Kakar, S.S.1    Grizzle, W.E.2    Neill, J.D.3
  • 113
    • 0028148727 scopus 로고
    • Expression and regulation of gonadotropin-releasing hormone (GnRH) and GnRH receptor messenger ribonucleic acids in human granulosaluteal cells
    • Peng C, Fan NC, Ligier M, Vaananen J, Leung PC 1994 Expression and regulation of gonadotropin-releasing hormone (GnRH) and GnRH receptor messenger ribonucleic acids in human granulosaluteal cells. Endocrinology 135:1740-1746
    • (1994) Endocrinology , vol.135 , pp. 1740-1746
    • Peng, C.1    Fan, N.C.2    Ligier, M.3    Vaananen, J.4    Leung, P.C.5
  • 114
    • 0027134802 scopus 로고
    • High affinity and direct antiproliferative effects of luteinizing hormone-releasing hormone analogs in human endometrial cancer cell lines
    • Emons G, Schroder B, Ortmann O, Westphalen S, Schulz KD, Schally AV 1993 High affinity and direct antiproliferative effects of luteinizing hormone-releasing hormone analogs in human endometrial cancer cell lines. J Clin Endocrinol Metab 77:1458-1464
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 1458-1464
    • Emons, G.1    Schroder, B.2    Ortmann, O.3    Westphalen, S.4    Schulz, K.D.5    Schally, A.V.6
  • 115
    • 0025317908 scopus 로고
    • Detection and partial characterization of receptors for [D-Trp6]-luteinizing hormone-releasing hormone and epidermal growth factor in human endometrial carcinoma
    • Srkalovic G, Wittliff JL, Schally AV 1990 Detection and partial characterization of receptors for [D-Trp6]-luteinizing hormone-releasing hormone and epidermal growth factor in human endometrial carcinoma. Cancer Res 50:1841-1846
    • (1990) Cancer Res , vol.50 , pp. 1841-1846
    • Srkalovic, G.1    Wittliff, J.L.2    Schally, A.V.3
  • 116
    • 0027944974 scopus 로고
    • Presence of gonadotropin-releasing hormone receptor and its messenger ribonucleic acid in endometrial carcinoma and endometrium
    • Imai A, Ohno T, Iida K, Fuseya T, Furui T, Tamaya T 1994 Presence of gonadotropin-releasing hormone receptor and its messenger ribonucleic acid in endometrial carcinoma and endometrium. Gynecol Oncol 55:144-148
    • (1994) Gynecol Oncol , vol.55 , pp. 144-148
    • Imai, A.1    Ohno, T.2    Iida, K.3    Fuseya, T.4    Furui, T.5    Tamaya, T.6
  • 117
    • 0033958986 scopus 로고    scopus 로고
    • Expression of GnRH receptor in human ectopic endometrial cells and inhibition of their proliferation by leuprolide acetate
    • Borroni R, Di Blasio AM, Gaffuri B, Santorsola R, Busacca M, Vigano P, Vignali M 2000 Expression of GnRH receptor in human ectopic endometrial cells and inhibition of their proliferation by leuprolide acetate. Mol Cell Endocrinol 159:37-43
    • (2000) Mol Cell Endocrinol , vol.159 , pp. 37-43
    • Borroni, R.1    Di Blasio, A.M.2    Gaffuri, B.3    Santorsola, R.4    Busacca, M.5    Vigano, P.6    Vignali, M.7
  • 118
    • 0035020249 scopus 로고    scopus 로고
    • Antiproliferative signaling of luteinizing hormone-releasing hormone in human endometrial and ovarian cancer cells through G protein αi-mediated activation of phosphotyrosine phosphatase
    • Grundker C, Volker P, Emons G 2001 Antiproliferative signaling of luteinizing hormone-releasing hormone in human endometrial and ovarian cancer cells through G protein αi-mediated activation of phosphotyrosine phosphatase. Endocrinology 142:2369-2380
    • (2001) Endocrinology , vol.142 , pp. 2369-2380
    • Grundker, C.1    Volker, P.2    Emons, G.3
  • 119
    • 0024405857 scopus 로고
    • Receptors for luteinizing hormone-releasing hormone, somatostatin, prolactin, and epidermal growth factor in rat and human prostate cancers and in benign prostate hyperplasia
    • Fekete A, Redding TW, Comaru-Schally AM, Pontes JE, Connelly RW, Srkalovic G, Schally AV 1989 Receptors for luteinizing hormone-releasing hormone, somatostatin, prolactin, and epidermal growth factor in rat and human prostate cancers and in benign prostate hyperplasia. Prostate 14:191-208
    • (1989) Prostate , vol.14 , pp. 191-208
    • Fekete, A.1    Redding, T.W.2    Comaru-Schally, A.M.3    Pontes, J.E.4    Connelly, R.W.5    Srkalovic, G.6    Schally, A.V.7
  • 120
    • 0026716297 scopus 로고
    • Antiproliferative effects of luteinizing hormone-releasing hormone agonists on the human prostatic cancer cell line LNCaP
    • Limonta P, Dondi D, Moretti RM, Maggi R, Motta M 1992 Antiproliferative effects of luteinizing hormone-releasing hormone agonists on the human prostatic cancer cell line LNCaP. J Clin Endocrinol Metab 75:207-212
    • (1992) J Clin Endocrinol Metab , vol.75 , pp. 207-212
    • Limonta, P.1    Dondi, D.2    Moretti, R.M.3    Maggi, R.4    Motta, M.5
  • 122
    • 0031671617 scopus 로고    scopus 로고
    • Expression of gonadotropin-releasing hormone (GnRH) and GnRH receptor mRNA in prostate cancer cells and effect of GnRH on the proliferation of prostate cancer cells
    • Bahk JY, Hyun JS, Lee H, Kim MO, Cho GJ, Lee BH, Choi WS 1998 Expression of gonadotropin-releasing hormone (GnRH) and GnRH receptor mRNA in prostate cancer cells and effect of GnRH on the proliferation of prostate cancer cells. Urol Res 26:259-264
    • (1998) Urol Res , vol.26 , pp. 259-264
    • Bahk, J.Y.1    Hyun, J.S.2    Lee, H.3    Kim, M.O.4    Cho, G.J.5    Lee, B.H.6    Choi, W.S.7
  • 123
    • 0033303530 scopus 로고    scopus 로고
    • The luteinizing hormone-releasing hormone receptor in human prostate cancer cells: Messenger ribonucleic acid expression, molecular size, and signal transduction pathway
    • Limonta P, Moretti RM, Marelli MM, Dondi D, Parenti M, Motta M 1999 The luteinizing hormone-releasing hormone receptor in human prostate cancer cells: messenger ribonucleic acid expression, molecular size, and signal transduction pathway. Endocrinology 140:5250-5256
    • (1999) Endocrinology , vol.140 , pp. 5250-5256
    • Limonta, P.1    Moretti, R.M.2    Marelli, M.M.3    Dondi, D.4    Parenti, M.5    Motta, M.6
  • 124
    • 0033963203 scopus 로고    scopus 로고
    • High incidence of receptors for luteinizing hormone-releasing hormone (LHRH) and LHRH receptor gene expression in human prostate cancers
    • Halmos G, Arencibia JM, Schally AV, Davis R, Bostwick DG 2000 High incidence of receptors for luteinizing hormone-releasing hormone (LHRH) and LHRH receptor gene expression in human prostate cancers. J Urol 163:623-629
    • (2000) J Urol , vol.163 , pp. 623-629
    • Halmos, G.1    Arencibia, J.M.2    Schally, A.V.3    Davis, R.4    Bostwick, D.G.5
  • 125
    • 0035371234 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone receptor expression in the human prostate
    • Tieva A, Stattin P, Wikstrom P, Bergh A, Damber JE 2001 Gonadotropin-releasing hormone receptor expression in the human prostate. Prostate 47:276-284
    • (2001) Prostate , vol.47 , pp. 276-284
    • Tieva, A.1    Stattin, P.2    Wikstrom, P.3    Bergh, A.4    Damber, J.E.5
  • 126
    • 0022388942 scopus 로고
    • Gonadotropin-releasing hormone binding sites in human breast carcinoma
    • Eidne KA, Flanagan CA, Millar RP 1985 Gonadotropin-releasing hormone binding sites in human breast carcinoma. Science 229: 989-991
    • (1985) Science , vol.229 , pp. 989-991
    • Eidne, K.A.1    Flanagan, C.A.2    Millar, R.P.3
  • 127
    • 0026545546 scopus 로고
    • Direct effects of luteinizing hormone-releasing hormone agonists and antagonists on MCF-7 mammary cancer cells
    • Segal-Abramson T, Kitroser H, Levy J, Schally AV, Sharoni Y 1992 Direct effects of luteinizing hormone-releasing hormone agonists and antagonists on MCF-7 mammary cancer cells. Proc Natl Acad Sci USA 89:2336-2339
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 2336-2339
    • Segal-Abramson, T.1    Kitroser, H.2    Levy, J.3    Schally, A.V.4    Sharoni, Y.5
  • 128
    • 0030923675 scopus 로고    scopus 로고
    • The genes for gonadotropin-releasing hormone and its receptor are expressed in human breast with fibrocystic disease and cancer
    • Kottler ML, Starzec A, Carre MC, Lagarde JP, Martin A, Counis R 1997 The genes for gonadotropin-releasing hormone and its receptor are expressed in human breast with fibrocystic disease and cancer. Int J Cancer 71:595-599
    • (1997) Int J Cancer , vol.71 , pp. 595-599
    • Kottler, M.L.1    Starzec, A.2    Carre, M.C.3    Lagarde, J.P.4    Martin, A.5    Counis, R.6
  • 130
    • 0028799871 scopus 로고
    • Expression of gonadotropin-releasing hormone and gonadotropin-releasing hormone receptor mRNAs in various non-reproductive human tissues
    • Kakar SS, Jennes L 1995 Expression of gonadotropin-releasing hormone and gonadotropin-releasing hormone receptor mRNAs in various non-reproductive human tissues. Cancer Lett 98:57-62
    • (1995) Cancer Lett , vol.98 , pp. 57-62
    • Kakar, S.S.1    Jennes, L.2
  • 131
    • 0036348467 scopus 로고    scopus 로고
    • Locally expressed LHRH receptors mediate the oncostatic and antimetastatic activity of LHRH agonists on melanoma cells
    • Moretti RM, Montagnani Marelli M, Van Groeninghen JC, Limonta P 2002 Locally expressed LHRH receptors mediate the oncostatic and antimetastatic activity of LHRH agonists on melanoma cells. J Clin Endocrinol Metab 87:3791-3797
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3791-3797
    • Moretti, R.M.1    Montagnani Marelli, M.2    Van Groeninghen, J.C.3    Limonta, P.4
  • 132
    • 0020045055 scopus 로고
    • Homologous regulation of gonadotropin-releasing hormone receptors in cultured pituitary cells
    • Loumaye E, Catt KJ 1982 Homologous regulation of gonadotropin-releasing hormone receptors in cultured pituitary cells. Science 215:983-985
    • (1982) Science , vol.215 , pp. 983-985
    • Loumaye, E.1    Catt, K.J.2
  • 133
    • 0023641189 scopus 로고
    • Homologous down-regulation of gonadotropin-releasing hormone receptor and desensitization of gonadotropes: Lack of dependence on protein kinase C
    • McArdle CA, Gorospe WC, Huckle WR, Conn PM 1987 Homologous down-regulation of gonadotropin-releasing hormone receptor and desensitization of gonadotropes: lack of dependence on protein kinase C. Mol Endocrinol 1:420-429
    • (1987) Mol Endocrinol , vol.1 , pp. 420-429
    • McArdle, C.A.1    Gorospe, W.C.2    Huckle, W.R.3    Conn, P.M.4
  • 134
    • 85003145419 scopus 로고
    • Homologous up-regulation of the gonadotropin-releasing hormone receptor in αT3-1 cells is associated with unchanged receptor messenger RNA (mRNA) levels and altered mRNA activity
    • Tsutsumi M, Laws SC, Sealfon SC 1993 Homologous up-regulation of the gonadotropin-releasing hormone receptor in αT3-1 cells is associated with unchanged receptor messenger RNA (mRNA) levels and altered mRNA activity. Mol Endocrinol 7:1625-1633
    • (1993) Mol Endocrinol , vol.7 , pp. 1625-1633
    • Tsutsumi, M.1    Laws, S.C.2    Sealfon, S.C.3
  • 135
    • 0028855756 scopus 로고
    • Translational regulation of the gonadotropin-releasing hormone receptor in αT3-1 cells
    • Tsutsumi M, Laws SC, Rodic V, Sealfon SC 1995 Translational regulation of the gonadotropin-releasing hormone receptor in αT3-1 cells. Endocrinology 136:1128-1136
    • (1995) Endocrinology , vol.136 , pp. 1128-1136
    • Tsutsumi, M.1    Laws, S.C.2    Rodic, V.3    Sealfon, S.C.4
  • 136
    • 0031047409 scopus 로고    scopus 로고
    • Differential effects of gonadotropin-releasing hormone (GnRH) pulse frequency on gonadotropin subunit and GnRH receptor messenger ribonucleic acid levels in vitro
    • Kaiser UB, Jakubowiak A, Steinberger A, Chin WW 1997 Differential effects of gonadotropin-releasing hormone (GnRH) pulse frequency on gonadotropin subunit and GnRH receptor messenger ribonucleic acid levels in vitro. Endocrinology 138:1224-1231
    • (1997) Endocrinology , vol.138 , pp. 1224-1231
    • Kaiser, U.B.1    Jakubowiak, A.2    Steinberger, A.3    Chin, W.W.4
  • 137
    • 0021919586 scopus 로고
    • Estradiol potentiation of gonadotropin-releasing hormone responsiveness in the anterior pituitary is mediated by an increase in GnRH receptor
    • Menon M, Peegel H, Katta V 1985 Estradiol potentiation of gonadotropin-releasing hormone responsiveness in the anterior pituitary is mediated by an increase in GnRH receptor. Am J Obstet Gynecol 151:534-540
    • (1985) Am J Obstet Gynecol , vol.151 , pp. 534-540
    • Menon, M.1    Peegel, H.2    Katta, V.3
  • 138
    • 0024268409 scopus 로고
    • Modulation of gonadotropin-releasing hormone receptor concentration in cultured female rat pituitary cells by estradiol treatment
    • Emons G, Hoffman HG, Brack C, Ortmann O, Strum R, Ball P, Knuppen R 1988 Modulation of gonadotropin-releasing hormone receptor concentration in cultured female rat pituitary cells by estradiol treatment. J Steroid Biochem 31:751-756
    • (1988) J Steroid Biochem , vol.31 , pp. 751-756
    • Emons, G.1    Hoffman, H.G.2    Brack, C.3    Ortmann, O.4    Strum, R.5    Ball, P.6    Knuppen, R.7
  • 139
    • 0027197988 scopus 로고
    • Regulation of rat pituitary gonadotropin-releasing hormone receptor mRNA levels in vivo and in vitro
    • Kaiser UB, Jakubowiak A, Steinberger A, Chin WW 1993 Regulation of rat pituitary gonadotropin-releasing hormone receptor mRNA levels in vivo and in vitro. Endocrinology 133:931-934
    • (1993) Endocrinology , vol.133 , pp. 931-934
    • Kaiser, U.B.1    Jakubowiak, A.2    Steinberger, A.3    Chin, W.W.4
  • 140
    • 0343618360 scopus 로고    scopus 로고
    • Estrogen regulation of gonadotropin-releasing hormone receptor messenger RNA in female rat pituitary tissue
    • Quinones-Jenab V, Jenab S, Ogawa S, Funabashi T, Weesner GD, Pfaff DW 1996 Estrogen regulation of gonadotropin-releasing hormone receptor messenger RNA in female rat pituitary tissue. Mol Brain Res 38:243-250
    • (1996) Mol Brain Res , vol.38 , pp. 243-250
    • Quinones-Jenab, V.1    Jenab, S.2    Ogawa, S.3    Funabashi, T.4    Weesner, G.D.5    Pfaff, D.W.6
  • 141
    • 0346849701 scopus 로고    scopus 로고
    • An AP-1-like motif mediates 17β-estradiol repression of GnRH receptor promoter via an estrogen receptor α-dependent mechanism in ovarian and breast cancer cells
    • Cheng CK, Chow BK, Leung PC 2003 An AP-1-like motif mediates 17β-estradiol repression of GnRH receptor promoter via an estrogen receptor α-dependent mechanism in ovarian and breast cancer cells. Mol Endocrinol 17:2613-2629
    • (2003) Mol Endocrinol , vol.17 , pp. 2613-2629
    • Cheng, C.K.1    Chow, B.K.2    Leung, P.C.3
  • 142
    • 0005688965 scopus 로고
    • Estradiol and inhibin increase a single polypeptide GnRH receptor in ovine pituitary cultures
    • Washington, DC, Abstract P1-110
    • Gardner DB, Miller WL, Estradiol and inhibin increase a single polypeptide GnRH receptor in ovine pituitary cultures. Program of the 77th Annual Meeting of The Endocrine Society, Washington, DC, 1995, p 140 (Abstract P1-110)
    • (1995) Program of the 77th Annual Meeting of the Endocrine Society , pp. 140
    • Gardner, D.B.1    Miller, W.L.2
  • 143
    • 0034463921 scopus 로고    scopus 로고
    • Estradiol induces and hyperglycosylates the receptor for ovine gonadotropin-releasing hormone
    • Gardner DB, Sebastian J, Miller WL 2000 Estradiol induces and hyperglycosylates the receptor for ovine gonadotropin-releasing hormone. Endocrinology 141:91-99
    • (2000) Endocrinology , vol.141 , pp. 91-99
    • Gardner, D.B.1    Sebastian, J.2    Miller, W.L.3
  • 144
    • 0025358977 scopus 로고
    • Inhibin increases and progesterone decrease receptor for gonadotropin-releasing hormone in ovine pituitary cultures
    • Laws SC, Beggs JM, Webster JC, Miller WL 1990 Inhibin increases and progesterone decrease receptor for gonadotropin-releasing hormone in ovine pituitary cultures. Endocrinology 127:373-380
    • (1990) Endocrinology , vol.127 , pp. 373-380
    • Laws, S.C.1    Beggs, J.M.2    Webster, J.C.3    Miller, W.L.4
  • 145
    • 0028345486 scopus 로고
    • Gonadal hormones and gonadotropin-releasing hormone (GnRH) alter messenger ribonucleic acid levels for GnRH receptors in sheep
    • Wu JC, Sealfon SC, Miller WL 1994 Gonadal hormones and gonadotropin-releasing hormone (GnRH) alter messenger ribonucleic acid levels for GnRH receptors in sheep. Endocrinology 134: 1846-1850
    • (1994) Endocrinology , vol.134 , pp. 1846-1850
    • Wu, J.C.1    Sealfon, S.C.2    Miller, W.L.3
  • 146
    • 0030614617 scopus 로고    scopus 로고
    • Concentrations of GnRH receptor and GnRH receptor mRNA in pituitary tissue of orchidectomized sheep: Effect of oestradiol, progesterone, and progesterone withdrawal
    • Sakurai H, Adams BM, Adems TE 1997 Concentrations of GnRH receptor and GnRH receptor mRNA in pituitary tissue of orchidectomized sheep: effect of oestradiol, progesterone, and progesterone withdrawal. J Endocrinol 152:91-98
    • (1997) J Endocrinol , vol.152 , pp. 91-98
    • Sakurai, H.1    Adams, B.M.2    Adems, T.E.3
  • 147
    • 0031857863 scopus 로고    scopus 로고
    • Estradiol and gonadotropin-releasing hormone (GnRH) interact to increase GnRH receptor expression in ovariectomized ewes after hypothalamic-pituitary disconnection
    • Kirkpatrick BL, Esquivel E, Moss GE, Hamemik DL, Wise ME 1998 Estradiol and gonadotropin-releasing hormone (GnRH) interact to increase GnRH receptor expression in ovariectomized ewes after hypothalamic-pituitary disconnection. Endocrine 8:225-229
    • (1998) Endocrine , vol.8 , pp. 225-229
    • Kirkpatrick, B.L.1    Esquivel, E.2    Moss, G.E.3    Hamemik, D.L.4    Wise, M.E.5
  • 148
    • 0035215296 scopus 로고    scopus 로고
    • Differential role of PR-A and -B isoforms in transcription regulation of human GnRH receptor gene
    • Cheng KW, Cheng CK, Leung PC 2001 Differential role of PR-A and -B isoforms in transcription regulation of human GnRH receptor gene. Mol Endocrinol 15:2078-2092
    • (2001) Mol Endocrinol , vol.15 , pp. 2078-2092
    • Cheng, K.W.1    Cheng, C.K.2    Leung, P.C.3
  • 149
    • 0028861749 scopus 로고
    • Homologous and heterologous regulation of gonadotropin-releasing hormone receptor gene expression in preovulatory rat granulosa cells
    • Olofsson JI, Conti CC, Leung PC 1995 Homologous and heterologous regulation of gonadotropin-releasing hormone receptor gene expression in preovulatory rat granulosa cells. Endocrinology 136:974-980
    • (1995) Endocrinology , vol.136 , pp. 974-980
    • Olofsson, J.I.1    Conti, C.C.2    Leung, P.C.3
  • 150
    • 0030039623 scopus 로고    scopus 로고
    • Human chorionic gonadotropin down-regulates the expression of gonadotropin-releasing hormone receptor gene in GT1-7 neurons
    • Li X, Lei ZM, Rao CV 1996 Human chorionic gonadotropin down-regulates the expression of gonadotropin-releasing hormone receptor gene in GT1-7 neurons. Endocrinology 137:899-904
    • (1996) Endocrinology , vol.137 , pp. 899-904
    • Li, X.1    Lei, Z.M.2    Rao, C.V.3
  • 152
    • 0036327276 scopus 로고    scopus 로고
    • Human chorionic gonadotropin-activated cAMP pathway regulates human placental GnRH receptor gene transcription in choriocarcinoma JEG-3 cells
    • Cheng KW, Leung PC 2002 Human chorionic gonadotropin-activated cAMP pathway regulates human placental GnRH receptor gene transcription in choriocarcinoma JEG-3 cells. J Clin Endocrinol Metab 87:3291-3299
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3291-3299
    • Cheng, K.W.1    Leung, P.C.2
  • 155
    • 0035741988 scopus 로고    scopus 로고
    • Influence of melatonin on basal and gonadotropin-stimulated progesterone and estradiol secretion of cultured human granulosa cells and in the superfused granulosa cell system
    • Bodis J, Koppan M, Kornya L, Tinneberg HR, Torok A 2001 Influence of melatonin on basal and gonadotropin-stimulated progesterone and estradiol secretion of cultured human granulosa cells and in the superfused granulosa cell system. Gynecol Obstet Invest 52:198-202
    • (2001) Gynecol Obstet Invest , vol.52 , pp. 198-202
    • Bodis, J.1    Koppan, M.2    Kornya, L.3    Tinneberg, H.R.4    Torok, A.5
  • 158
    • 0026547786 scopus 로고
    • Activin-A stimulates the synthesis of gonadotropin-releasing hormone receptors
    • Braden TD, Conn PM 1992 Activin-A stimulates the synthesis of gonadotropin-releasing hormone receptors. Endocrinology 130: 2101-2105
    • (1992) Endocrinology , vol.130 , pp. 2101-2105
    • Braden, T.D.1    Conn, P.M.2
  • 159
    • 0029879685 scopus 로고    scopus 로고
    • Transcriptional activation of the gonadotropin-releasing hormone receptor gene by activin A
    • Fernandez-Vazquez G, Kaiser UB, Albarracin CT, Chin WW 1996 Transcriptional activation of the gonadotropin-releasing hormone receptor gene by activin A. Mol Endocrinol 10:356-366
    • (1996) Mol Endocrinol , vol.10 , pp. 356-366
    • Fernandez-Vazquez, G.1    Kaiser, U.B.2    Albarracin, C.T.3    Chin, W.W.4
  • 160
    • 0031694570 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone deficiency in the human (idiopathic hypogonadotropic hypogonadism and Kallmann's syndrome): Pathophysiological and genetic considerations
    • Seminara SB, Hayes FJ, Crowley Jr WF 1998 Gonadotropin-releasing hormone deficiency in the human (idiopathic hypogonadotropic hypogonadism and Kallmann's syndrome): pathophysiological and genetic considerations. Endocr Rev 19:521-539
    • (1998) Endocr Rev , vol.19 , pp. 521-539
    • Seminara, S.B.1    Hayes, F.J.2    Crowley Jr., W.F.3
  • 164
    • 0030698188 scopus 로고    scopus 로고
    • A family with hypogonadotropic hypogonadism and mutations in the gonadotropin-releasing hormone receptor
    • de Roux N, Young J, Misrahi M, Genet R, Chanson P, Schaison G, Milgrom E 1997 A family with hypogonadotropic hypogonadism and mutations in the gonadotropin-releasing hormone receptor. N Engl J Med 337:1597-1602
    • (1997) N Engl J Med , vol.337 , pp. 1597-1602
    • De Roux, N.1    Young, J.2    Misrahi, M.3    Genet, R.4    Chanson, P.5    Schaison, G.6    Milgrom, E.7
  • 165
    • 17144439793 scopus 로고    scopus 로고
    • Mutations in gonadotropin-releasing hormone receptor gene cause hypogonadotropic hypogonadism
    • Layman LC, Cohen DP, Jin M, Xie J, Li Z, Reindollar RH, Bolbolan S 1998 Mutations in gonadotropin-releasing hormone receptor gene cause hypogonadotropic hypogonadism. Nat Genet 18:14-15
    • (1998) Nat Genet , vol.18 , pp. 14-15
    • Layman, L.C.1    Cohen, D.P.2    Jin, M.3    Xie, J.4    Li, Z.5    Reindollar, R.H.6    Bolbolan, S.7
  • 167
    • 0033017005 scopus 로고    scopus 로고
    • The same molecular defects of the gonadotropin-releasing hormone receptor determine variable degree of hypogonadism in affected kindred
    • de Roux N, Young J, Brailly-Tabard S, Misrhai M, Milgrom E, Schaison G 1999 The same molecular defects of the gonadotropin-releasing hormone receptor determine variable degree of hypogonadism in affected kindred. J Clin Endocrinol Metab 84:567-572
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 567-572
    • De Roux, N.1    Young, J.2    Brailly-Tabard, S.3    Misrhai, M.4    Milgrom, E.5    Schaison, G.6
  • 168
    • 0033304606 scopus 로고    scopus 로고
    • Complete hypogonadotropic hypogonadism associated with a novel inactivating mutation of the gonadotropin-releasing hormone receptor
    • Pralong FP, Gomez F, Castillo E, Cotecchia S, Abuin L, Aubert ML, Portmann L 1999 Complete hypogonadotropic hypogonadism associated with a novel inactivating mutation of the gonadotropin-releasing hormone receptor. J Clin Endocrinol Metab 84:3811-3816
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 3811-3816
    • Pralong, F.P.1    Gomez, F.2    Castillo, E.3    Cotecchia, S.4    Abuin, L.5    Aubert, M.L.6    Portmann, L.7
  • 169
    • 0033694510 scopus 로고    scopus 로고
    • A new compound heterozygous mutation of the gonadotropin-releasing hormone receptor (L314X, Q106R) in a woman with complete hypogonadotropic hypogonadism: Chronic estrogen administration amplifies the gonadotropin defect
    • Kottler ML, Chauvin S, Lahlou N, Harris CE, Johnston CJ, Lagarde JP, Bouchard P, Farid N, Counis R 2000 A new compound heterozygous mutation of the gonadotropin-releasing hormone receptor (L314X, Q106R) in a woman with complete hypogonadotropic hypogonadism: chronic estrogen administration amplifies the gonadotropin defect. J Clin Endocrinol Metab 85:3002-3008
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3002-3008
    • Kottler, M.L.1    Chauvin, S.2    Lahlou, N.3    Harris, C.E.4    Johnston, C.J.5    Lagarde, J.P.6    Bouchard, P.7    Farid, N.8    Counis, R.9
  • 171
    • 0034966302 scopus 로고    scopus 로고
    • Two novel mutations in the gonadotropin-releasing hormone receptor gene in Brazilian patients with hypogonadotropic hypogonadism and normal olfaction
    • Costa EM, Bedecarrats GY, Mendonca BB, Arnhold IJ, Kaiser UB, Latronico AC 2001 Two novel mutations in the gonadotropin-releasing hormone receptor gene in Brazilian patients with hypogonadotropic hypogonadism and normal olfaction. J Clin Endocrinol Metab 86:2680-2686
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 2680-2686
    • Costa, E.M.1    Bedecarrats, G.Y.2    Mendonca, B.B.3    Arnhold, I.J.4    Kaiser, U.B.5    Latronico, A.C.6
  • 172
    • 0038697838 scopus 로고    scopus 로고
    • Mutation of Ala(171)Thr stabilizes the gonadotropin-releasing hormone receptor in its inactive conformation, causing familial hypogonadotropic hypogonadism
    • Karges B, Karges W, Mine M, Ludwig L, Kuhne R, Milgrom E, de Roux N 2003 Mutation of Ala(171)Thr stabilizes the gonadotropin-releasing hormone receptor in its inactive conformation, causing familial hypogonadotropic hypogonadism. J Clin Endocrinol Metab 88:1873-1879
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 1873-1879
    • Karges, B.1    Karges, W.2    Mine, M.3    Ludwig, L.4    Kuhne, R.5    Milgrom, E.6    De Roux, N.7
  • 173
    • 0034978722 scopus 로고    scopus 로고
    • The fertile eunuch variant of idiopathic hypogonadotropic hypogonadism: Spontaneous reversal associated with a homozygous mutation in the gonadotropin-releasing hormone receptor
    • Pitteloud N, Boepple PA, DeCruz S, Valkenburgh SB, Crowley Jr WF, Hayes FJ 2001 The fertile eunuch variant of idiopathic hypogonadotropic hypogonadism: spontaneous reversal associated with a homozygous mutation in the gonadotropin-releasing hormone receptor. J Clin Endocrinol Metab 86:2470-2475
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 2470-2475
    • Pitteloud, N.1    Boepple, P.A.2    DeCruz, S.3    Valkenburgh, S.B.4    Crowley Jr., W.F.5    Hayes, F.J.6
  • 174
    • 0035723564 scopus 로고    scopus 로고
    • A novel homozygous mutation in the second transmembrane domain of gonadotropin-releasing hormone receptor gene
    • Soderlund D, Canto P, de la Chesnaye E, Ulloa-Aguirre A, Mendez JP 2001 A novel homozygous mutation in the second transmembrane domain of gonadotropin-releasing hormone receptor gene. Clin Endocrinol (Oxf) 54:493-498
    • (2001) Clin Endocrinol (Oxf) , vol.54 , pp. 493-498
    • Soderlund, D.1    Canto, P.2    De La Chesnaye, E.3    Ulloa-Aguirre, A.4    Mendez, J.P.5
  • 175
    • 0347362854 scopus 로고    scopus 로고
    • Unexpected effects of epitope and chimeric tags on gonadotropin-releasing hormone receptors: Implications for understanding the molecular etiology of hypogonadotropic hypogonadism
    • Brothers SP, Janovick J, Conn PM 2003 Unexpected effects of epitope and chimeric tags on gonadotropin-releasing hormone receptors: implications for understanding the molecular etiology of hypogonadotropic hypogonadism. J Clin Endocrinol Metab 88: 6107-6112
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 6107-6112
    • Brothers, S.P.1    Janovick, J.2    Conn, P.M.3
  • 176
    • 0344059035 scopus 로고    scopus 로고
    • Structure-activity relations of successful pharmacologic chaperones for rescue of naturally occurring and manufactured mutants of the gonadotropin-releasing hormone receptor
    • Janovick JA, Goulet M, Bush E, Greer J, Wettlaufer DG, Conn PM 2003 Structure-activity relations of successful pharmacologic chaperones for rescue of naturally occurring and manufactured mutants of the gonadotropin-releasing hormone receptor. J Pharmacol Exp Ther 305:608-614
    • (2003) J Pharmacol Exp Ther , vol.305 , pp. 608-614
    • Janovick, J.A.1    Goulet, M.2    Bush, E.3    Greer, J.4    Wettlaufer, D.G.5    Conn, P.M.6
  • 177
    • 0242500958 scopus 로고    scopus 로고
    • Misrouted cell surface receptors as a novel disease etiology and potential therapeutic target: The case of hypogonadotropic hypogonadism due to gonadotropin-releasing hormone resistance
    • Ulloa-Aguirre A, Janovick J, Leanos-Miranda A, Conn PM 2003 Misrouted cell surface receptors as a novel disease etiology and potential therapeutic target: the case of hypogonadotropic hypogonadism due to gonadotropin-releasing hormone resistance. Expert Opin Ther Targets 7:175-185
    • (2003) Expert Opin Ther Targets , vol.7 , pp. 175-185
    • Ulloa-Aguirre, A.1    Janovick, J.2    Leanos-Miranda, A.3    Conn, P.M.4
  • 178
    • 0033279280 scopus 로고    scopus 로고
    • Steroidogenic factor-1 interacts with a gonadotrope-specific element within the first exon of the human gonadotropin-releasing hormone receptor gene to mediate gonadotrope-specific expression
    • Ngan ES, Cheng PK, Leung PC, Chow BK 1999 Steroidogenic factor-1 interacts with a gonadotrope-specific element within the first exon of the human gonadotropin-releasing hormone receptor gene to mediate gonadotrope-specific expression. Endocrinology 140:2452-2462
    • (1999) Endocrinology , vol.140 , pp. 2452-2462
    • Ngan, E.S.1    Cheng, P.K.2    Leung, P.C.3    Chow, B.K.4
  • 179
    • 0242330293 scopus 로고    scopus 로고
    • Steroidogenic factor-1 (SF-1) and the gonadotrope-specific element (GSE) enhance basal and pituitary adenylate cyclase-activating polypeptide (PACAP)-stimulated transcription of the human glycoprotein hormone α-subunit gene (αGSU) in gonadotropes
    • Fowkes RC, Desclozeaux M, Patel MV, Aylwin SJ, King P, Ingraham HA, Burrin JM 2003 Steroidogenic factor-1 (SF-1) and the gonadotrope-specific element (GSE) enhance basal and pituitary adenylate cyclase-activating polypeptide (PACAP)-stimulated transcription of the human glycoprotein hormone α-subunit gene (αGSU) in gonadotropes. Mol Endocrinol 17:2177-2188
    • (2003) Mol Endocrinol , vol.17 , pp. 2177-2188
    • Fowkes, R.C.1    Desclozeaux, M.2    Patel, M.V.3    Aylwin, S.J.4    King, P.5    Ingraham, H.A.6    Burrin, J.M.7
  • 180
    • 0028783348 scopus 로고
    • Different composite regulatory elements direct expression of the human α subunit gene to pituitary and placenta
    • Heckert LL, Schulte K, Nilson JH 1995 Different composite regulatory elements direct expression of the human α subunit gene to pituitary and placenta. J Biol Chem 270:26497-26504
    • (1995) J Biol Chem , vol.270 , pp. 26497-26504
    • Heckert, L.L.1    Schulte, K.2    Nilson, J.H.3
  • 181
    • 0030002926 scopus 로고    scopus 로고
    • Stimulation of luteinizing hormone β gene promoter activity by the orphan nuclear receptor, Steroidogenic factor-1
    • Halvorson LM, Kaiser UB, Chin WW 1996 Stimulation of luteinizing hormone β gene promoter activity by the orphan nuclear receptor, Steroidogenic factor-1. J Biol Chem 271:6645-6650
    • (1996) J Biol Chem , vol.271 , pp. 6645-6650
    • Halvorson, L.M.1    Kaiser, U.B.2    Chin, W.W.3
  • 182
    • 0034713158 scopus 로고    scopus 로고
    • Steroidogenic factor (SF-1) is essential for ovarian development and function
    • Hanley NA, Ikeda Y, Luo X, Parker KL 2000 Steroidogenic factor (SF-1) is essential for ovarian development and function. Mol Cell Endocrinol 163:27-32
    • (2000) Mol Cell Endocrinol , vol.163 , pp. 27-32
    • Hanley, N.A.1    Ikeda, Y.2    Luo, X.3    Parker, K.L.4
  • 184
    • 0030666563 scopus 로고    scopus 로고
    • The tripartite basal enhancer of the gonadotropin-releasing hormone (GnRH) receptor gene promoter regulates cell-specific expression through a novel GnRH receptor activating sequence
    • Duval DL, Nelson SE, Clay CM 1997 The tripartite basal enhancer of the gonadotropin-releasing hormone (GnRH) receptor gene promoter regulates cell-specific expression through a novel GnRH receptor activating sequence. Mol Endocrinol 11:1814-1821
    • (1997) Mol Endocrinol , vol.11 , pp. 1814-1821
    • Duval, D.L.1    Nelson, S.E.2    Clay, C.M.3
  • 185
    • 0031785733 scopus 로고    scopus 로고
    • Differentially expressed messenger RNA isoforms of the human estrogen receptor-α gene are generated by alternative splicing and promoter usage
    • Flouriot G, Griffin C, Kenealy M, Sonntag-Buck V, Cannon F 1998 Differentially expressed messenger RNA isoforms of the human estrogen receptor-α gene are generated by alternative splicing and promoter usage. Mol Endocrinol 12:1939-1954
    • (1998) Mol Endocrinol , vol.12 , pp. 1939-1954
    • Flouriot, G.1    Griffin, C.2    Kenealy, M.3    Sonntag-Buck, V.4    Cannon, F.5
  • 187
    • 0035978412 scopus 로고    scopus 로고
    • Structure, expression profile and alternative processing of the human phosphatidylethanolamine N-methyltransferase (PEMT) gene
    • Shields DJ, Agellon LB, Vance DE 2001 Structure, expression profile and alternative processing of the human phosphatidylethanolamine N-methyltransferase (PEMT) gene. Biochim Biophys Acta 1532:105-114
    • (2001) Biochim Biophys Acta , vol.1532 , pp. 105-114
    • Shields, D.J.1    Agellon, L.B.2    Vance, D.E.3
  • 188
    • 0035053010 scopus 로고    scopus 로고
    • Functional mapping of a placenta-specific upstream promoter for human gonadotropin-releasing hormone receptor gene
    • Cheng KW, Chow BK, Leung PC 2001 Functional mapping of a placenta-specific upstream promoter for human gonadotropin-releasing hormone receptor gene. Endocrinology 142:1506-1516
    • (2001) Endocrinology , vol.142 , pp. 1506-1516
    • Cheng, K.W.1    Chow, B.K.2    Leung, P.C.3
  • 189
    • 85047684055 scopus 로고    scopus 로고
    • Characterization of a new upstream gonadotropin-releasing hormone receptor promoter in human ovarian granulosa-luteal cells
    • Cheng CK, Yeung CM, Chow BK, Leung PC 2002 Characterization of a new upstream gonadotropin-releasing hormone receptor promoter in human ovarian granulosa-luteal cells. Mol Endocrinol 16:1552-1564
    • (2002) Mol Endocrinol , vol.16 , pp. 1552-1564
    • Cheng, C.K.1    Yeung, C.M.2    Chow, B.K.3    Leung, P.C.4
  • 190
    • 0033534448 scopus 로고    scopus 로고
    • Identification and characterization of the gonadotropin-releasing hormone response elements in the mouse gonadotropin-releasing hormone receptor gene
    • Norwitz ER, Cardona GR, Jeong KH, Chin WW 1999 Identification and characterization of the gonadotropin-releasing hormone response elements in the mouse gonadotropin-releasing hormone receptor gene. J Biol Chem 274:867-880
    • (1999) J Biol Chem , vol.274 , pp. 867-880
    • Norwitz, E.R.1    Cardona, G.R.2    Jeong, K.H.3    Chin, W.W.4
  • 191
    • 0033306831 scopus 로고    scopus 로고
    • Homologous regulation of the gonadotropin-releasing hormone receptor gene is partially mediated by protein kinase C activation of an activator protein-1 element
    • White BR, Duval DL, Mulvaney JM, Roberson MS, Clay CM 1999 Homologous regulation of the gonadotropin-releasing hormone receptor gene is partially mediated by protein kinase C activation of an activator protein-1 element. Mol Endocrinol 13:566-577
    • (1999) Mol Endocrinol , vol.13 , pp. 566-577
    • White, B.R.1    Duval, D.L.2    Mulvaney, J.M.3    Roberson, M.S.4    Clay, C.M.5
  • 193
    • 0037020178 scopus 로고    scopus 로고
    • Direct binding of AP-1 (Fos/Jun) proteins to a SMAD binding element facilitates both gonadotropin-releasing hormone (GnRH)- and activin-mediated transcriptional activation of the mouse GnRH receptor gene
    • Norwitz ER, Xu S, Xu J, Spiryda LB, Park JS, Jeong KH, McGee EA, Kaiser UB 2002 Direct binding of AP-1 (Fos/Jun) proteins to a SMAD binding element facilitates both gonadotropin-releasing hormone (GnRH)- and activin-mediated transcriptional activation of the mouse GnRH receptor gene. J Biol Chem 277:37469-37479
    • (2002) J Biol Chem , vol.277 , pp. 37469-37479
    • Norwitz, E.R.1    Xu, S.2    Xu, J.3    Spiryda, L.B.4    Park, J.S.5    Jeong, K.H.6    McGee, E.A.7    Kaiser, U.B.8
  • 194
    • 0033752089 scopus 로고    scopus 로고
    • Transcriptional down-regulation of human gonadotropin-releasing hormone (GnRH) receptor gene by GnRH: Role of protein kinase C and activating protein 1
    • Cheng KW, Ngan ES, Kang SK, Chow BK, Leung PC 2000 Transcriptional down-regulation of human gonadotropin-releasing hormone (GnRH) receptor gene by GnRH: role of protein kinase C and activating protein 1. Endocrinology 141:3611-3622
    • (2000) Endocrinology , vol.141 , pp. 3611-3622
    • Cheng, K.W.1    Ngan, E.S.2    Kang, S.K.3    Chow, B.K.4    Leung, P.C.5
  • 195
    • 0021268231 scopus 로고
    • Adenosine 3′,5′-monophosphate derivatives increase gonadotropin-releasing hormone receptors in cultured pituitary cells
    • Young LS, Naik SI, Clayton RN 1984 Adenosine 3′,5′- monophosphate derivatives increase gonadotropin-releasing hormone receptors in cultured pituitary cells. Endocrinology 114:2114-2122
    • (1984) Endocrinology , vol.114 , pp. 2114-2122
    • Young, L.S.1    Naik, S.I.2    Clayton, R.N.3
  • 196
    • 0028842051 scopus 로고
    • Adenosine 3′,5′-cyclic monophosphate and the self-priming effect of gonadotropin-releasing hormone
    • Abdilnour G, Bourne GA 1995 Adenosine 3′,5′-cyclic monophosphate and the self-priming effect of gonadotropin-releasing hormone. Mol Cell Endocrinol 107:1-7
    • (1995) Mol Cell Endocrinol , vol.107 , pp. 1-7
    • Abdilnour, G.1    Bourne, G.A.2
  • 197
    • 0028803357 scopus 로고
    • Effect of cAMP on GnRH stimulated LH secretion from individual pituitary gonadotropes
    • Cassina P, Sellers J, Neill JD 1995 Effect of cAMP on GnRH stimulated LH secretion from individual pituitary gonadotropes. Mol Cell Endocrinol 114:127-135
    • (1995) Mol Cell Endocrinol , vol.114 , pp. 127-135
    • Cassina, P.1    Sellers, J.2    Neill, J.D.3
  • 198
    • 0031730721 scopus 로고    scopus 로고
    • Transcriptional activation of gonadotropin-releasing hormone (GnRH) receptor gene by GnRH and cyclic adenosine monophosphate
    • Lin X, Conn PM 1998 Transcriptional activation of gonadotropin-releasing hormone (GnRH) receptor gene by GnRH and cyclic adenosine monophosphate. Endocrinology 139:3896-3902
    • (1998) Endocrinology , vol.139 , pp. 3896-3902
    • Lin, X.1    Conn, P.M.2
  • 199
    • 0035811543 scopus 로고    scopus 로고
    • Human gonadotropin-releasing hormone receptor gene transcription: Up-regulation by 3′,5′-cyclic adenosine monophosphate/protein kinase A pathway
    • Cheng KW, Leung PC 2001 Human gonadotropin-releasing hormone receptor gene transcription: up-regulation by 3′,5′-cyclic adenosine monophosphate/protein kinase A pathway. Mol Cell Endocrinol 181:15-26
    • (2001) Mol Cell Endocrinol , vol.181 , pp. 15-26
    • Cheng, K.W.1    Leung, P.C.2
  • 201
    • 0025788098 scopus 로고
    • Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73
    • Smeal T, Binetruy B, Mercola DA, Birrer M, Karin M 1991 Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73. Nature 354:494-496
    • (1991) Nature , vol.354 , pp. 494-496
    • Smeal, T.1    Binetruy, B.2    Mercola, D.A.3    Birrer, M.4    Karin, M.5
  • 202
    • 0343527941 scopus 로고    scopus 로고
    • Differential expression of human gonadotropin-releasing hormone receptor gene in pituitary and ovarian cells
    • Kang SK, Cheng KW, Ngan ES, Chow BK, Choi KC, Leung PC 2000 Differential expression of human gonadotropin-releasing hormone receptor gene in pituitary and ovarian cells. Mol Cell Endocrinol 162:157-166
    • (2000) Mol Cell Endocrinol , vol.162 , pp. 157-166
    • Kang, S.K.1    Cheng, K.W.2    Ngan, E.S.3    Chow, B.K.4    Choi, K.C.5    Leung, P.C.6
  • 203
    • 0036893336 scopus 로고    scopus 로고
    • Oct-1 is involved in the transcriptional repression of the gonadotropin-releasing hormone receptor gene
    • Cheng CK, Yeung CM, Hoo RL, Chow BK, Leung PC 2002 Oct-1 is involved in the transcriptional repression of the gonadotropin-releasing hormone receptor gene. Endocrinology 143:4693-4701
    • (2002) Endocrinology , vol.143 , pp. 4693-4701
    • Cheng, C.K.1    Yeung, C.M.2    Hoo, R.L.3    Chow, B.K.4    Leung, P.C.5
  • 205
    • 0029816592 scopus 로고    scopus 로고
    • Coupling of gonadotropin-releasing hormone receptor to Gi protein in human reproductive tract tumors
    • Imai A, Takagi H, Horibe S, Fuseya T, Tamaya T 1996 Coupling of gonadotropin-releasing hormone receptor to Gi protein in human reproductive tract tumors. J Clin Endocrinol Metab 81:3249-3253
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3249-3253
    • Imai, A.1    Takagi, H.2    Horibe, S.3    Fuseya, T.4    Tamaya, T.5
  • 206
    • 0037199927 scopus 로고    scopus 로고
    • Involvement of both G(q/11) and G(s) proteins in gonadotropin-releasing hormone receptor-mediated signaling in LβT2 cells
    • Liu F, Usui I, Evans LG, Austin DA, Mellon PL, Olefsky JM, Webster NJ 2002 Involvement of both G(q/11) and G(s) proteins in gonadotropin-releasing hormone receptor-mediated signaling in LβT2 cells. J Biol Chem 277:32099-32108
    • (2002) J Biol Chem , vol.277 , pp. 32099-32108
    • Liu, F.1    Usui, I.2    Evans, L.G.3    Austin, D.A.4    Mellon, P.L.5    Olefsky, J.M.6    Webster, N.J.7
  • 207
  • 208
    • 0037418302 scopus 로고    scopus 로고
    • An agonist-induced switch in G protein coupling of the gonadotropin-releasing hormone receptor regulates pulsatile neuropeptide secretion
    • Krsmanovic LZ, Mores N, Navarro CE, Arora KK, Catt KJ 2003 An agonist-induced switch in G protein coupling of the gonadotropin-releasing hormone receptor regulates pulsatile neuropeptide secretion. Proc Natl Acad Sci USA 100:2969-2974
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 2969-2974
    • Krsmanovic, L.Z.1    Mores, N.2    Navarro, C.E.3    Arora, K.K.4    Catt, K.J.5
  • 209
    • 0036098860 scopus 로고    scopus 로고
    • Activation and targeting of mitogen-activated protein kinases by G-protein-coupled receptors
    • Luttrell LM 2002 Activation and targeting of mitogen-activated protein kinases by G-protein-coupled receptors. Can J Physiol Pharmacol 80:375-382
    • (2002) Can J Physiol Pharmacol , vol.80 , pp. 375-382
    • Luttrell, L.M.1
  • 210
    • 0035952645 scopus 로고    scopus 로고
    • New mechanisms in heptahelical receptor signaling to mitogen-activated protein kinase cascades
    • Pierce KL, Luttrell LM, Lefkowitz RJ 2001 New mechanisms in heptahelical receptor signaling to mitogen-activated protein kinase cascades. Oncogene 20:1532-1539
    • (2001) Oncogene , vol.20 , pp. 1532-1539
    • Pierce, K.L.1    Luttrell, L.M.2    Lefkowitz, R.J.3
  • 211
    • 0032928614 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase: Conservation of a three-kinase module from yeast to human
    • Widmann C, Gibson S, Jarpe MB, Johnson GL 1999 Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human. Physiol Rev 79:143-180
    • (1999) Physiol Rev , vol.79 , pp. 143-180
    • Widmann, C.1    Gibson, S.2    Jarpe, M.B.3    Johnson, G.L.4
  • 212
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • Chang L, Karin M 2001 Mammalian MAP kinase signalling cascades. Nature 410:37-40
    • (2001) Nature , vol.410 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 213
    • 0037032817 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
    • Johnson GL, Lapadat R 2002 Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 298:1911-1912
    • (2002) Science , vol.298 , pp. 1911-1912
    • Johnson, G.L.1    Lapadat, R.2
  • 214
    • 0034119581 scopus 로고    scopus 로고
    • Activation of MAPK cascades by G-protein-coupled receptors: The case of gonadotropin-releasing hormone receptor
    • Naor Z, Benard O, Seger R 2000 Activation of MAPK cascades by G-protein-coupled receptors: the case of gonadotropin-releasing hormone receptor. Trends Endocrinol Metab 11:91-99
    • (2000) Trends Endocrinol Metab , vol.11 , pp. 91-99
    • Naor, Z.1    Benard, O.2    Seger, R.3
  • 215
    • 0035676783 scopus 로고    scopus 로고
    • Intracellular signaling pathways mediated by the gonadotropin-releasing hormone (GnRH) receptor
    • Kraus S, Naor Z, Seger R 2001 Intracellular signaling pathways mediated by the gonadotropin-releasing hormone (GnRH) receptor. Arch Med Res 32:499-509
    • (2001) Arch Med Res , vol.32 , pp. 499-509
    • Kraus, S.1    Naor, Z.2    Seger, R.3
  • 217
    • 0035895872 scopus 로고    scopus 로고
    • Role of dynamin, Src, and Ras in the protein kinase C-mediated activation of ERK by gonadotropin-releasing hormone
    • Benard O, Naor Z, Seger R 2001 Role of dynamin, Src, and Ras in the protein kinase C-mediated activation of ERK by gonadotropin-releasing hormone. J Biol Chem 276:4554-4563
    • (2001) J Biol Chem , vol.276 , pp. 4554-4563
    • Benard, O.1    Naor, Z.2    Seger, R.3
  • 218
    • 0036185866 scopus 로고    scopus 로고
    • GnRH activates ERK1/2 leading to the induction of c-fos and LHβ protein expression in LβT2 cells
    • Liu F, Austin DA, Mellon PL, Olefsky JM, Webster NJ 2002 GnRH activates ERK1/2 leading to the induction of c-fos and LHβ protein expression in LβT2 cells. Mol Endocrinol 16:419-434
    • (2002) Mol Endocrinol , vol.16 , pp. 419-434
    • Liu, F.1    Austin, D.A.2    Mellon, P.L.3    Olefsky, J.M.4    Webster, N.J.5
  • 219
    • 0033569875 scopus 로고    scopus 로고
    • Calcium influx through L-type channels is required for selective activation of extracellular signal-regulated kinase by gonadotropin-releasing hormone
    • Mulvaney JM, Zhang T, Fewtrell C, Roberson MS 1999 Calcium influx through L-type channels is required for selective activation of extracellular signal-regulated kinase by gonadotropin-releasing hormone. J Biol Chem 274:29796-29804
    • (1999) J Biol Chem , vol.274 , pp. 29796-29804
    • Mulvaney, J.M.1    Zhang, T.2    Fewtrell, C.3    Roberson, M.S.4
  • 220
    • 0041355360 scopus 로고    scopus 로고
    • Constitutive localization of the gonadotropin-releasing hormone (GnRH) receptor to low density membrane microdomains is necessary for GnRH signaling to ERK
    • Navratil AM, Bliss SP, Berghorn KA, Haughian JM, Farmerie TA, Graham JK, Clay CM, Roberson MS 2003 Constitutive localization of the gonadotropin- releasing hormone (GnRH) receptor to low density membrane microdomains is necessary for GnRH signaling to ERK. J Biol Chem 278:31593-31602
    • (2003) J Biol Chem , vol.278 , pp. 31593-31602
    • Navratil, A.M.1    Bliss, S.P.2    Berghorn, K.A.3    Haughian, J.M.4    Farmerie, T.A.5    Graham, J.K.6    Clay, C.M.7    Roberson, M.S.8
  • 221
    • 0032230247 scopus 로고    scopus 로고
    • Stimulation of Jun N-terminal kinase (JNK) by gonadotropin-releasing hormone in pituitary αT3-1 cell line is mediated by protein kinase C, c-Src, and CDC42
    • Levi NL, Hanoch T, Benard O, Rozenblat M, Harris D, Reiss N, Naor Z, Seger R 1998 Stimulation of Jun N-terminal kinase (JNK) by gonadotropin- releasing hormone in pituitary αT3-1 cell line is mediated by protein kinase C, c-Src, and CDC42. Mol Endocrinol 12:815-824
    • (1998) Mol Endocrinol , vol.12 , pp. 815-824
    • Levi, N.L.1    Hanoch, T.2    Benard, O.3    Rozenblat, M.4    Harris, D.5    Reiss, N.6    Naor, Z.7    Seger, R.8
  • 222
    • 0034640289 scopus 로고    scopus 로고
    • Divergent signaling pathways requiring discrete calcium signals mediate concurrent activation of two mitogen-activated protein kinases by gonadotropin-releasing hormone
    • Mulvaney JM, Roberson MS 2000 Divergent signaling pathways requiring discrete calcium signals mediate concurrent activation of two mitogen-activated protein kinases by gonadotropin-releasing hormone. J Biol Chem 275:14182-14189
    • (2000) J Biol Chem , vol.275 , pp. 14182-14189
    • Mulvaney, J.M.1    Roberson, M.S.2
  • 223
    • 0032963917 scopus 로고    scopus 로고
    • Activation of the p38 mitogen-activated protein kinase pathway by gonadotropin-releasing hormone
    • Roberson MS, Zhang T, Li HL, Mulvaney JM 1999 Activation of the p38 mitogen-activated protein kinase pathway by gonadotropin-releasing hormone. Endocrinology 140:1310-1318
    • (1999) Endocrinology , vol.140 , pp. 1310-1318
    • Roberson, M.S.1    Zhang, T.2    Li, H.L.3    Mulvaney, J.M.4
  • 224
    • 0041355688 scopus 로고    scopus 로고
    • c-Src is activated by EGF-receptor in a pathway that mediates JNK and ERK activation by gonadotropin-releasing hormone in COS7 cells
    • Kraus S, Benard O, Naor Z, Seger R 2003 c-Src is activated by EGF-receptor in a pathway that mediates JNK and ERK activation by gonadotropin-releasing hormone in COS7 cells. J Biol Chem 278:32618-32630
    • (2003) J Biol Chem , vol.278 , pp. 32618-32630
    • Kraus, S.1    Benard, O.2    Naor, Z.3    Seger, R.4
  • 225
    • 0037474304 scopus 로고    scopus 로고
    • Dependence of gonadotropin-releasing hormone-induced neuronal MAPK signaling on epidermal growth factor receptor transactivation
    • Shah BH, Soh JW, Catt KJ 2003 Dependence of gonadotropin-releasing hormone-induced neuronal MAPK signaling on epidermal growth factor receptor transactivation. J Biol Chem 278:2866-2875
    • (2003) J Biol Chem , vol.278 , pp. 2866-2875
    • Shah, B.H.1    Soh, J.W.2    Catt, K.J.3
  • 226
    • 0032496280 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone receptors with intracellular carboxyl-terminal tails undergo acute desensitization of total inositol phosphate production and exhibit accelerated internalization kinetics
    • Heding A, Vrecl M, Bogerd J, McGregor A, Sellar R, Taylor PL, Eidne KA 1998 Gonadotropin-releasing hormone receptors with intracellular carboxyl-terminal tails undergo acute desensitization of total inositol phosphate production and exhibit accelerated internalization kinetics. J Biol Chem 273:11472-11477
    • (1998) J Biol Chem , vol.273 , pp. 11472-11477
    • Heding, A.1    Vrecl, M.2    Bogerd, J.3    McGregor, A.4    Sellar, R.5    Taylor, P.L.6    Eidne, K.A.7
  • 227
    • 0033570130 scopus 로고    scopus 로고
    • Lack of a C-terminal tail in the mammalian gonadotropin-releasing hormone receptor confers resistance to agonist-dependent phosphorylation and rapid desensitization
    • Willars GB, Heding A, Vrecl M, Sellar R, Blomenrohr M, Nahorski SR, Eidne KA 1999 Lack of a C-terminal tail in the mammalian gonadotropin-releasing hormone receptor confers resistance to agonist-dependent phosphorylation and rapid desensitization. J Biol Chem 274:30146-30153
    • (1999) J Biol Chem , vol.274 , pp. 30146-30153
    • Willars, G.B.1    Heding, A.2    Vrecl, M.3    Sellar, R.4    Blomenrohr, M.5    Nahorski, S.R.6    Eidne, K.A.7
  • 228
    • 0028242680 scopus 로고
    • Absence of rapid desensitization of the mouse gonadotropin-releasing hormone receptor
    • Davidson JS, Wakefield IK, Millar RP 1994 Absence of rapid desensitization of the mouse gonadotropin-releasing hormone receptor. Biochem J 300:299-302
    • (1994) Biochem J , vol.300 , pp. 299-302
    • Davidson, J.S.1    Wakefield, I.K.2    Millar, R.P.3
  • 229
    • 0031757743 scopus 로고    scopus 로고
    • Agonist-induced endocytosis and recycling of the gonadotropin-releasing hormone receptor: Effect of β-arrestin on internalization kinetics
    • Vrecl M, Anderson L, Hanyaloglu A, McGregor AM, Groarke AD, Milligan G, Taylor PL, Eidne KA 1998 Agonist-induced endocytosis and recycling of the gonadotropin-releasing hormone receptor: effect of β-arrestin on internalization kinetics. Mol Endocrinol 12:1818-1829
    • (1998) Mol Endocrinol , vol.12 , pp. 1818-1829
    • Vrecl, M.1    Anderson, L.2    Hanyaloglu, A.3    McGregor, A.M.4    Groarke, A.D.5    Milligan, G.6    Taylor, P.L.7    Eidne, K.A.8
  • 230
    • 0036241442 scopus 로고    scopus 로고
    • Signaling, cycling and desensitization of gonadotropin-releasing hormone receptors
    • McArdle CA, Franklin J, Green L, Hislop JN 2002 Signaling, cycling and desensitization of gonadotropin-releasing hormone receptors. J Endocrinol 173:1-11
    • (2002) J Endocrinol , vol.173 , pp. 1-11
    • McArdle, C.A.1    Franklin, J.2    Green, L.3    Hislop, J.N.4
  • 231
    • 0035955742 scopus 로고    scopus 로고
    • Differential internalization of mammalian and non-mammalian gonadotropin-releasing hormone receptors. Uncoupling of dynamin-dependent internalization from mitogen-activated protein kinase signaling
    • Hislop JL, Everest HM, Flynn A, Harding T, Uney JB, Troskie BE, Millar RP, McArdle CA 2001 Differential internalization of mammalian and non-mammalian gonadotropin-releasing hormone receptors. Uncoupling of dynamin-dependent internalization from mitogen-activated protein kinase signaling. J Biol Chem 276:39685-39694
    • (2001) J Biol Chem , vol.276 , pp. 39685-39694
    • Hislop, J.L.1    Everest, H.M.2    Flynn, A.3    Harding, T.4    Uney, J.B.5    Troskie, B.E.6    Millar, R.P.7    McArdle, C.A.8
  • 232
    • 0034748094 scopus 로고    scopus 로고
    • Signaling and anti-proliferative effects mediated by gonadotropin- releasing hormone receptors after expression in breast cancer cells using recombinant adenovirus
    • Everest HM, Hislop JN, Harding T, Uney JB, Flynn A, Millar RP, McArdle CA 2001 Signaling and anti-proliferative effects mediated by gonadotropin- releasing hormone receptors after expression in breast cancer cells using recombinant adenovirus. Endocrinology 142:4663-4672
    • (2001) Endocrinology , vol.142 , pp. 4663-4672
    • Everest, H.M.1    Hislop, J.N.2    Harding, T.3    Uney, J.B.4    Flynn, A.5    Millar, R.P.6    McArdle, C.A.7
  • 234
    • 0029198265 scopus 로고
    • Molecular biology of gonadotropins
    • Hamemik DL 1995 Molecular biology of gonadotropins. J Reprod Fertil Suppl 49:257-269
    • (1995) J Reprod Fertil Suppl , vol.49 , pp. 257-269
    • Hamemik, D.L.1
  • 235
    • 0030457786 scopus 로고    scopus 로고
    • Calcium and glycoprotein hormone α-subunit gene expression and secretion in αT3-1 gonadotropes
    • Holdstock JG, Aylwin SJ, Burrin JM 1996 Calcium and glycoprotein hormone α-subunit gene expression and secretion in αT3-1 gonadotropes. Mol Endocrinol 10:1308-1317
    • (1996) Mol Endocrinol , vol.10 , pp. 1308-1317
    • Holdstock, J.G.1    Aylwin, S.J.2    Burrin, J.M.3
  • 236
    • 0037318494 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase and c-Src, but not Jun N-terminal kinase, are involved in basal and gonadotropin-releasing hormone-stimulated activity of the glycoprotein hormone α-sub-unit promoter
    • Harris D, Chuderland D, Bonfil D, Kraus S, Seger R, Naor Z 2003 Extracellular signal-regulated kinase and c-Src, but not Jun N-terminal kinase, are involved in basal and gonadotropin-releasing hormone-stimulated activity of the glycoprotein hormone α-sub-unit promoter. Endocrinology 144:612-622
    • (2003) Endocrinology , vol.144 , pp. 612-622
    • Harris, D.1    Chuderland, D.2    Bonfil, D.3    Kraus, S.4    Seger, R.5    Naor, Z.6
  • 237
    • 0032230357 scopus 로고    scopus 로고
    • Differential gonadotropin-releasing hormone stimulation of rat luteinizing hormone subunit gene transcription by calcium influx and mitogen-activated protein kinase-signaling pathways
    • Week J, Fallest PC, Pitt LK, Shupnik MA 1998 Differential gonadotropin-releasing hormone stimulation of rat luteinizing hormone subunit gene transcription by calcium influx and mitogen-activated protein kinase-signaling pathways. Mol Endocrinol 12:451-457
    • (1998) Mol Endocrinol , vol.12 , pp. 451-457
    • Week, J.1    Fallest, P.C.2    Pitt, L.K.3    Shupnik, M.A.4
  • 238
    • 0031762011 scopus 로고    scopus 로고
    • Differential use of signal transduction pathways in the gonadotropin-releasing hormone-mediated regulation of gonadotropin subunit gene expression
    • Saunders BD, Sabbagh E, Chin WW, Kaiser UB 1998 Differential use of signal transduction pathways in the gonadotropin-releasing hormone-mediated regulation of gonadotropin subunit gene expression. Endocrinology 139:1835-1843
    • (1998) Endocrinology , vol.139 , pp. 1835-1843
    • Saunders, B.D.1    Sabbagh, E.2    Chin, W.W.3    Kaiser, U.B.4
  • 239
    • 0036721555 scopus 로고    scopus 로고
    • Different signaling pathways control acute induction versus long-term repression of LHβ transcription by GnRH
    • Vasilyev W, Lawson MA, Dipaolo D, Webster NJ, Mellon PL 2002 Different signaling pathways control acute induction versus long-term repression of LHβ transcription by GnRH. Endocrinology 143:3414-3426
    • (2002) Endocrinology , vol.143 , pp. 3414-3426
    • Vasilyev, W.1    Lawson, M.A.2    Dipaolo, D.3    Webster, N.J.4    Mellon, P.L.5
  • 240
    • 0032814586 scopus 로고    scopus 로고
    • Gonadotropin releasing hormone activates the equine luteinizing hormone β promoter through a protein kinase C/mitogen activated protein kinase pathway
    • Call GB, Wolfe MW 1999 Gonadotropin releasing hormone activates the equine luteinizing hormone β promoter through a protein kinase C/mitogen activated protein kinase pathway. Biol Reprod 61:715-723
    • (1999) Biol Reprod , vol.61 , pp. 715-723
    • Call, G.B.1    Wolfe, M.W.2
  • 241
    • 0032557554 scopus 로고    scopus 로고
    • Sp1 binds to the rat luteinizing hormone β (LHβ) gene promoter and mediates gonadotropin-releasing hormone-stimulated expression of the LHβ subunit gene
    • Kaiser UB, Sabbagh E, Chen MT, Chin WW, Saunders BD 1998 Sp1 binds to the rat luteinizing hormone β (LHβ) gene promoter and mediates gonadotropin-releasing hormone-stimulated expression of the LHβ subunit gene. J Biol Chem 273:12943-12951
    • (1998) J Biol Chem , vol.273 , pp. 12943-12951
    • Kaiser, U.B.1    Sabbagh, E.2    Chen, M.T.3    Chin, W.W.4    Saunders, B.D.5
  • 242
    • 0031766617 scopus 로고    scopus 로고
    • Identification of cis-acting deoxyribonucleic acid elements that mediate gonadotropin-releasing hormone stimulation of the rat luteinizing hormone β-subunit gene
    • Kaiser UB, Sabbagh E, Saunders BD, Chin WW 1998 Identification of cis-acting deoxyribonucleic acid elements that mediate gonadotropin-releasing hormone stimulation of the rat luteinizing hormone β-subunit gene. Endocrinology 139:2443-2451
    • (1998) Endocrinology , vol.139 , pp. 2443-2451
    • Kaiser, U.B.1    Sabbagh, E.2    Saunders, B.D.3    Chin, W.W.4
  • 243
    • 0034463302 scopus 로고    scopus 로고
    • Divergent and composite gonadotropin-releasing hormone responsive elements in the rat luteinizing hormone subunit genes
    • Week J, Anderson AC, Jenkins S, Fallest PC, Shupnik MA 2000 Divergent and composite gonadotropin-releasing hormone responsive elements in the rat luteinizing hormone subunit genes. Mol Endocrinol 14:472-485
    • (2000) Mol Endocrinol , vol.14 , pp. 472-485
    • Week, J.1    Anderson, A.C.2    Jenkins, S.3    Fallest, P.C.4    Shupnik, M.A.5
  • 244
    • 0032893316 scopus 로고    scopus 로고
    • The protein kinase C system acts through the early growth response protein 1 to increase LHβ gene expression in synergy with steroidogenic factor-1
    • Halvorson LM, Kaiser UB, Chin WW 1999 The protein kinase C system acts through the early growth response protein 1 to increase LHβ gene expression in synergy with steroidogenic factor-1. Mol Endocrinol 13:106-116
    • (1999) Mol Endocrinol , vol.13 , pp. 106-116
    • Halvorson, L.M.1    Kaiser, U.B.2    Chin, W.W.3
  • 245
    • 0032940188 scopus 로고    scopus 로고
    • Egr-1 is a downstream effector of GnRH and synergizes by direct interaction with Ptx1 and SF-1 to enhance luteinizing hormone β gene transcription
    • Tremblay JJ, Drouin J 1999 Egr-1 is a downstream effector of GnRH and synergizes by direct interaction with Ptx1 and SF-1 to enhance luteinizing hormone β gene transcription. Mol Cell Biol 19:2567-2576
    • (1999) Mol Cell Biol , vol.19 , pp. 2567-2576
    • Tremblay, J.J.1    Drouin, J.2
  • 246
    • 0036224365 scopus 로고    scopus 로고
    • Transcriptional activation of the ovine follicle-stimulating hormone-β gene by gonadotropin-releasing hormone involves multiple signal transduction pathways
    • Vasilyev W, Pernasetti F, Rosenberg SB, Barsoum MJ, Austin DA, Webster NJ, Mellon PL 2002 Transcriptional activation of the ovine follicle-stimulating hormone-β gene by gonadotropin-releasing hormone involves multiple signal transduction pathways. Endocrinology 143:1651-1659
    • (2002) Endocrinology , vol.143 , pp. 1651-1659
    • Vasilyev, W.1    Pernasetti, F.2    Rosenberg, S.B.3    Barsoum, M.J.4    Austin, D.A.5    Webster, N.J.6    Mellon, P.L.7
  • 247
    • 0031735917 scopus 로고    scopus 로고
    • Transcriptional activation of the ovine follicle-stimulating hormone β-subunit gene by gonadotropin-releasing hormone: Involvement of two activating protein-1 sites and protein kinase C
    • Strahl BD, Huang HJ, Sebastian J, Ghosh BR, Miller WL 1998 Transcriptional activation of the ovine follicle-stimulating hormone β-subunit gene by gonadotropin-releasing hormone: involvement of two activating protein-1 sites and protein kinase C. Endocrinology 139:4455-4465
    • (1998) Endocrinology , vol.139 , pp. 4455-4465
    • Strahl, B.D.1    Huang, H.J.2    Sebastian, J.3    Ghosh, B.R.4    Miller, W.L.5
  • 248
    • 0035020036 scopus 로고    scopus 로고
    • Cell-specific transcriptional regulation of follicle-stimulating hormone-β by activin and gonadotropin-releasing hormone in the LβT2 pituitary gonadotrope cell model
    • Pernasetti F, Vasilyev W, Rosenberg SB, Bailey JS, Huang HJ, Miller WL, Mellon PL 2001 Cell-specific transcriptional regulation of follicle-stimulating hormone-β by activin and gonadotropin-releasing hormone in the LβT2 pituitary gonadotrope cell model. Endocrinology 142:2284-2295
    • (2001) Endocrinology , vol.142 , pp. 2284-2295
    • Pernasetti, F.1    Vasilyev, W.2    Rosenberg, S.B.3    Bailey, J.S.4    Huang, H.J.5    Miller, W.L.6    Mellon, P.L.7
  • 249
    • 0027905031 scopus 로고
    • Rhythmic exocyotsis stimulated by GnRH-induced calcium oscillations in rat gonadotropes
    • Tse A, Tse FW, Almers W, Hille B 1993 Rhythmic exocyotsis stimulated by GnRH-induced calcium oscillations in rat gonadotropes. Science 260:82-84
    • (1993) Science , vol.260 , pp. 82-84
    • Tse, A.1    Tse, F.W.2    Almers, W.3    Hille, B.4
  • 250
    • 0028805276 scopus 로고
    • Novel aspects of GnRH-induced intracellular signaling and secretion in pituitary gonadotrophs
    • Stojilkovic SS, Catt KJ 1995 Novel aspects of GnRH-induced intracellular signaling and secretion in pituitary gonadotrophs. J Neuroendocrinol 7:739-757
    • (1995) J Neuroendocrinol , vol.7 , pp. 739-757
    • Stojilkovic, S.S.1    Catt, K.J.2
  • 251
    • 0023693964 scopus 로고
    • Gonadotropin-releasing hormone stimulates luteinizing hormone secretion by extracellular calcium-dependent and independent mechanisms
    • Chang JP, Stojilkovic SS, Graeter JS, Catt KJ 1988 Gonadotropin-releasing hormone stimulates luteinizing hormone secretion by extracellular calcium-dependent and independent mechanisms. Endocrinology 123:87-97
    • (1988) Endocrinology , vol.123 , pp. 87-97
    • Chang, J.P.1    Stojilkovic, S.S.2    Graeter, J.S.3    Catt, K.J.4
  • 253
    • 0024204781 scopus 로고
    • Evidence for the role of protein kinase C in luteinizing hormone synthesis and secretion
    • Stojilkovic SS, Chang JP, Ngo D, Catt KJ 1988 Evidence for the role of protein kinase C in luteinizing hormone synthesis and secretion. J Biol Chem 263:17307-17311
    • (1988) J Biol Chem , vol.263 , pp. 17307-17311
    • Stojilkovic, S.S.1    Chang, J.P.2    Ngo, D.3    Catt, K.J.4
  • 254
    • 0024535251 scopus 로고
    • Gonadotropin-releasing hormone-stimulated luteinizing hormone (LH) release from ovine gonadotrophs in culture is separate from phorbol ester-stimulated LH release
    • Beggs MJ, Miller WL 1989 Gonadotropin-releasing hormone-stimulated luteinizing hormone (LH) release from ovine gonadotrophs in culture is separate from phorbol ester-stimulated LH release. Endocrinology 124:667-674
    • (1989) Endocrinology , vol.124 , pp. 667-674
    • Beggs, M.J.1    Miller, W.L.2
  • 255
    • 0023281039 scopus 로고
    • Phosphorylation substrates for protein kinase C in intact pituitary cells: Characterization of a receptor-mediated event using novel gonadotropin-releasing hormone analogues
    • Strulovici B, Tahilramani R, Nestor JJ 1987 Phosphorylation substrates for protein kinase C in intact pituitary cells: characterization of a receptor-mediated event using novel gonadotropin-releasing hormone analogues. Biochemistry 26:6005-6011
    • (1987) Biochemistry , vol.26 , pp. 6005-6011
    • Strulovici, B.1    Tahilramani, R.2    Nestor, J.J.3
  • 256
    • 0024209739 scopus 로고
    • Mechanisms of secretory responses to gonadotropin-releasing hormone and phorbol esters in cultured pituitary cells
    • Stojilkovic SS, Chang JP, Izumi SI, Tsaka K, Catt KJ 1988 Mechanisms of secretory responses to gonadotropin-releasing hormone and phorbol esters in cultured pituitary cells. J Biol Chem 263: 17301-17306
    • (1988) J Biol Chem , vol.263 , pp. 17301-17306
    • Stojilkovic, S.S.1    Chang, J.P.2    Izumi, S.I.3    Tsaka, K.4    Catt, K.J.5
  • 259
    • 0018168286 scopus 로고
    • Hypophysial responses to continuous and intermittent delivery of hypothalamic gonadotropin-releasing hormone
    • Belchetz PE, Plant TM, Nakai Y, Keogh EJ, Knobil E 1978 Hypophysial responses to continuous and intermittent delivery of hypothalamic gonadotropin-releasing hormone. Science 202:631-633
    • (1978) Science , vol.202 , pp. 631-633
    • Belchetz, P.E.1    Plant, T.M.2    Nakai, Y.3    Keogh, E.J.4    Knobil, E.5
  • 260
    • 0028862330 scopus 로고
    • Desensitization of gonadotropin-releasing hormone action in the gonadotrope-derived αT3-1 cell line
    • McArdle CA, Forrest-Owen W, Willars G, Davidson J, Poch A, Kratzmeier M 1995 Desensitization of gonadotropin-releasing hormone action in the gonadotrope-derived αT3-1 cell line. Endocrinology 136:4864-4871
    • (1995) Endocrinology , vol.136 , pp. 4864-4871
    • McArdle, C.A.1    Forrest-Owen, W.2    Willars, G.3    Davidson, J.4    Poch, A.5    Kratzmeier, M.6
  • 261
    • 0038030829 scopus 로고    scopus 로고
    • Relative effect of gonadotropin-releasing hormone (GnRH)-I and GnRH-II on gonadotropin release
    • Densmore VS, Urbanski HF 2003 Relative effect of gonadotropin-releasing hormone (GnRH)-I and GnRH-II on gonadotropin release. J Clin Endocrinol Metab 88:2126-2134
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2126-2134
    • Densmore, V.S.1    Urbanski, H.F.2
  • 262
    • 0141460511 scopus 로고    scopus 로고
    • Evidence that gonadotropin-releasing hormone (GnRH) II stimulates luteinizing hormone and follicle-stimulating hormone secretion from monkey pituitary cultures by activating the GnRH I receptor
    • Okada Y, Murota-Kawano A, Kakar SS, Winters SJ 2003 Evidence that gonadotropin-releasing hormone (GnRH) II stimulates luteinizing hormone and follicle-stimulating hormone secretion from monkey pituitary cultures by activating the GnRH I receptor. Biol Reprod 69:1356-1361
    • (2003) Biol Reprod , vol.69 , pp. 1356-1361
    • Okada, Y.1    Murota-Kawano, A.2    Kakar, S.S.3    Winters, S.J.4
  • 263
    • 0024994130 scopus 로고
    • Steroidogenesis in vitro of human granulosa-luteal cells pretreated in vivo with gonadotropin-releasing hormone analogs
    • Pellicer A, Miro F 1990 Steroidogenesis in vitro of human granulosa-luteal cells pretreated in vivo with gonadotropin-releasing hormone analogs. Fertil Steril 54:590-596
    • (1990) Fertil Steril , vol.54 , pp. 590-596
    • Pellicer, A.1    Miro, F.2
  • 264
    • 0027510552 scopus 로고
    • Effect of a gonadotropin-releasing hormone agonist on luteinizing hormone receptors and Steroidogenesis in ovarian cells
    • Guerrero HE, Stein P, Asch RH, de Fried EP, Tesone M 1993 Effect of a gonadotropin-releasing hormone agonist on luteinizing hormone receptors and Steroidogenesis in ovarian cells. Fertil Steril 59:803-808
    • (1993) Fertil Steril , vol.59 , pp. 803-808
    • Guerrero, H.E.1    Stein, P.2    Asch, R.H.3    De Fried, E.P.4    Tesone, M.5
  • 265
    • 0028289981 scopus 로고
    • Influence of gonadotropin releasing hormone (GnRH) and a GnRH-agonist on granulosa cell Steroidogenesis
    • Gaetje R 1994 Influence of gonadotropin releasing hormone (GnRH) and a GnRH-agonist on granulosa cell Steroidogenesis. Clin Exp Obstet Gynecol 21:164-169
    • (1994) Clin Exp Obstet Gynecol , vol.21 , pp. 164-169
    • Gaetje, R.1
  • 266
    • 0034036956 scopus 로고    scopus 로고
    • Effects of gonadotropin-releasing hormone agonists on human ovarian steroid secretion in vivo and in vitro-results of a perspective, randomized in-vitro fertilization study
    • Dor J, Bider D, Shulman A, Levron JL, Shine S, Mashiach S, Rabinovici J 2000 Effects of gonadotropin-releasing hormone agonists on human ovarian steroid secretion in vivo and in vitro-results of a perspective, randomized in-vitro fertilization study. Hum Reprod 15:1225-1230
    • (2000) Hum Reprod , vol.15 , pp. 1225-1230
    • Dor, J.1    Bider, D.2    Shulman, A.3    Levron, J.L.4    Shine, S.5    Mashiach, S.6    Rabinovici, J.7
  • 267
    • 0034704389 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone activates mitogen-activated protein kinase in human ovarian and placental cells
    • Rang SK, Tai CJ, Cheng KW, Leung PC 2000 Gonadotropin-releasing hormone activates mitogen-activated protein kinase in human ovarian and placental cells. Mol Cell Endocrinol 170:143-151
    • (2000) Mol Cell Endocrinol , vol.170 , pp. 143-151
    • Rang, S.K.1    Tai, C.J.2    Cheng, K.W.3    Leung, P.C.4
  • 268
    • 0021971578 scopus 로고
    • Growth of human breast cancer cells inhibited by a luteinizing hormone-releasing hormone agonist
    • Miller WR, Scott WN, Morris R, Fraser HM, Sharpe RM 1985 Growth of human breast cancer cells inhibited by a luteinizing hormone-releasing hormone agonist. Nature 313:231-233
    • (1985) Nature , vol.313 , pp. 231-233
    • Miller, W.R.1    Scott, W.N.2    Morris, R.3    Fraser, H.M.4    Sharpe, R.M.5
  • 269
    • 0036164170 scopus 로고    scopus 로고
    • Biology of the gonadotropin-releasing hormone system in gynecological cancers
    • Grundker C, Gunthert AR, Westphalen S, Emons G 2002 Biology of the gonadotropin-releasing hormone system in gynecological cancers. Eur J Endocrinol 146:1-14
    • (2002) Eur J Endocrinol , vol.146 , pp. 1-14
    • Grundker, C.1    Gunthert, A.R.2    Westphalen, S.3    Emons, G.4
  • 270
    • 0037937565 scopus 로고    scopus 로고
    • Potential role of gonadotropin-releasing hormone (GnRH)-I and GnRH-II in the ovary and ovarian cancer
    • Kang SK, Choi KC, Yang HS, Leung PC 2003 Potential role of gonadotropin-releasing hormone (GnRH)-I and GnRH-II in the ovary and ovarian cancer. Endocr Relat Cancer 10:169-177
    • (2003) Endocr Relat Cancer , vol.10 , pp. 169-177
    • Kang, S.K.1    Choi, K.C.2    Yang, H.S.3    Leung, P.C.4
  • 272
    • 0032723879 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinase/extracellular signal-regulated kinase cascade in gonadotropin-releasing hormone-induced growth inhibition of a human ovarian cancer cell line
    • Kimura A, Ohmichi M, Kurachi H, Ikegami H, Hayakawa J, Tasaka K, Kanda Y, Nishio Y, Jikihara H, Matsuura N, Murata Y 1999 Role of mitogen-activated protein kinase/extracellular signal-regulated kinase cascade in gonadotropin-releasing hormone-induced growth inhibition of a human ovarian cancer cell line. Cancer Res 59:5133-5142
    • (1999) Cancer Res , vol.59 , pp. 5133-5142
    • Kimura, A.1    Ohmichi, M.2    Kurachi, H.3    Ikegami, H.4    Hayakawa, J.5    Tasaka, K.6    Kanda, Y.7    Nishio, Y.8    Jikihara, H.9    Matsuura, N.10    Murata, Y.11
  • 273
    • 0036554706 scopus 로고    scopus 로고
    • Luteinizing hormone-releasing hormone agonist limits DU-145 prostate cancer growth by attenuating epidermal growth factor signaling
    • Wells A, Souto JC, Solava J, Kassis J, Bailey KJ, Turner T 2002 Luteinizing hormone-releasing hormone agonist limits DU-145 prostate cancer growth by attenuating epidermal growth factor signaling. Clin Cancer Res 8:1251-1257
    • (2002) Clin Cancer Res , vol.8 , pp. 1251-1257
    • Wells, A.1    Souto, J.C.2    Solava, J.3    Kassis, J.4    Bailey, K.J.5    Turner, T.6
  • 274
    • 0004933908 scopus 로고    scopus 로고
    • Cell cycle arrest in endometrial carcinoma cells exposed to gonadotropin-releasing hormone analog
    • Kim JW, Lee YS, Kim BK, Park DC, Lee JM, Kim IK, Namkoong SE 1999 Cell cycle arrest in endometrial carcinoma cells exposed to gonadotropin-releasing hormone analog. Gynecol Oncol 73:368-371
    • (1999) Gynecol Oncol , vol.73 , pp. 368-371
    • Kim, J.W.1    Lee, Y.S.2    Kim, B.K.3    Park, D.C.4    Lee, J.M.5    Kim, I.K.6    Namkoong, S.E.7
  • 275
    • 0036296651 scopus 로고    scopus 로고
    • Luteinizing hormone-releasing hormone induces JunD-DNA binding and extends cell cycle in human ovarian cancer cells
    • Gunthert AR, Grundker C, Hollmann K, Emons G 2002 Luteinizing hormone-releasing hormone induces JunD-DNA binding and extends cell cycle in human ovarian cancer cells. Biochem Biophys Res Commun 294:11-15
    • (2002) Biochem Biophys Res Commun , vol.294 , pp. 11-15
    • Gunthert, A.R.1    Grundker, C.2    Hollmann, K.3    Emons, G.4
  • 276
    • 0028325891 scopus 로고
    • Mouse JunD negatively regulates fibroblast growth and antagonizes transformation by ras
    • Pfarr CM, Mechta F, Spyrou G, Lallemand D, Carillo S, Yaniv M 1994 Mouse JunD negatively regulates fibroblast growth and antagonizes transformation by ras. Cell 76:747-760
    • (1994) Cell , vol.76 , pp. 747-760
    • Pfarr, C.M.1    Mechta, F.2    Spyrou, G.3    Lallemand, D.4    Carillo, S.5    Yaniv, M.6
  • 277
    • 0030067871 scopus 로고    scopus 로고
    • Evidence for coupling of phosphotyrosine phosphatase to gonadotropin-releasing hormone receptor in ovarian carcinoma membrane
    • Imai A, Takagi H, Furui T, Horibe S, Fuseya T, Tamaya T 1996 Evidence for coupling of phosphotyrosine phosphatase to gonadotropin-releasing hormone receptor in ovarian carcinoma membrane. Cancer 77:132-137
    • (1996) Cancer , vol.77 , pp. 132-137
    • Imai, A.1    Takagi, H.2    Furui, T.3    Horibe, S.4    Fuseya, T.5    Tamaya, T.6
  • 278
    • 0030614823 scopus 로고    scopus 로고
    • Gi protein activation of gonadotropin-releasing hormone-mediated protein dephosphorylation in human endometrial carcinoma
    • Imai A, Horibe S, Takagi A, Tamaya T 1997 Gi protein activation of gonadotropin-releasing hormone-mediated protein dephosphorylation in human endometrial carcinoma. Am J Obstet Gynecol 176:371-376
    • (1997) Am J Obstet Gynecol , vol.176 , pp. 371-376
    • Imai, A.1    Horibe, S.2    Takagi, A.3    Tamaya, T.4
  • 279
    • 0032922082 scopus 로고    scopus 로고
    • Luteinizing hormone-releasing hormone agonists interfere with the mitogenic activity of the insulin-like growth factor system in androgen-independent prostate cancer cells
    • Marelli MM, Moretti RM, Dondi D, Motta M, Limonta P 1999 Luteinizing hormone-releasing hormone agonists interfere with the mitogenic activity of the insulin-like growth factor system in androgen-independent prostate cancer cells. Endocrinology 140: 329-334
    • (1999) Endocrinology , vol.140 , pp. 329-334
    • Marelli, M.M.1    Moretti, R.M.2    Dondi, D.3    Motta, M.4    Limonta, P.5
  • 280
    • 0036605041 scopus 로고    scopus 로고
    • Inhibitory effects of a luteinizing hormone-releasing hormone agonist on basal and epidermal growth factor-induced cell proliferation and metastasis-associated properties in human epidermoid carcinoma A431 cells
    • Huang YT, Hwang JJ, Lee LT, Liebow C, Lee PP, Ke FC, Lo TB, Serially AV, Lee MT 2002 Inhibitory effects of a luteinizing hormone-releasing hormone agonist on basal and epidermal growth factor-induced cell proliferation and metastasis-associated properties in human epidermoid carcinoma A431 cells. Int J Cancer 99:505-513
    • (2002) Int J Cancer , vol.99 , pp. 505-513
    • Huang, Y.T.1    Hwang, J.J.2    Lee, L.T.3    Liebow, C.4    Lee, P.P.5    Ke, F.C.6    Lo, T.B.7    Serially, A.V.8    Lee, M.T.9
  • 281
    • 0029803245 scopus 로고    scopus 로고
    • Luteinizing hormone-releasing hormone agonist triptorelin antagonizes signal transduction and mitogenic activity of epidermal growth factor in human ovarian and endometrial cancer cell lines
    • Emons G, Muller V, Ortmann O, Grossmann G, Trautner U, von Stuckrad B, Schulz KD, Schally AV 1996 Luteinizing hormone-releasing hormone agonist triptorelin antagonizes signal transduction and mitogenic activity of epidermal growth factor in human ovarian and endometrial cancer cell lines. Int J Oncol 9:1129-1137
    • (1996) Int J Oncol , vol.9 , pp. 1129-1137
    • Emons, G.1    Muller, V.2    Ortmann, O.3    Grossmann, G.4    Trautner, U.5    Von Stuckrad, B.6    Schulz, K.D.7    Schally, A.V.8
  • 282
    • 0033842808 scopus 로고    scopus 로고
    • Luteinizing hormone-releasing hormone (LHRH) agonist triptorelin and antagonist cetrorelix inhibit EGF-induced c-fos expression in human gynecological cancers
    • Grundker C, Volker P, Schulz KD, Emons G 2000 Luteinizing hormone-releasing hormone (LHRH) agonist triptorelin and antagonist cetrorelix inhibit EGF-induced c-fos expression in human gynecological cancers. Gynecol Oncol 78:194-202
    • (2000) Gynecol Oncol , vol.78 , pp. 194-202
    • Grundker, C.1    Volker, P.2    Schulz, K.D.3    Emons, G.4
  • 283
    • 10344248844 scopus 로고    scopus 로고
    • Luteinizing hormone-releasing hormone agonists interfere with the stimulatory actions of epidermal growth factor in human prostatic cancer cell lines, LNCaP and DU 145
    • Moretti RM, Marelli MM, Dondi D, Poletti A, Martini L, Motta M, Limonta P 1996 Luteinizing hormone-releasing hormone agonists interfere with the stimulatory actions of epidermal growth factor in human prostatic cancer cell lines, LNCaP and DU 145. J Clin Endocrinol Metab 81:3930-3937
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3930-3937
    • Moretti, R.M.1    Marelli, M.M.2    Dondi, D.3    Poletti, A.4    Martini, L.5    Motta, M.6    Limonta, P.7
  • 284
    • 0029027714 scopus 로고
    • Evidence for tight coupling of gonadotropin-releasing hormone receptors to phosphatidy linositol kinase in plasma membrane from ovarian carcinomas
    • Takagi H, Imai A, Furui T, Horibe S, Fuseya T, Tamaya T 1995 Evidence for tight coupling of gonadotropin-releasing hormone receptors to phosphatidy linositol kinase in plasma membrane from ovarian carcinomas. Gynecol Oncol 58:110-115
    • (1995) Gynecol Oncol , vol.58 , pp. 110-115
    • Takagi, H.1    Imai, A.2    Furui, T.3    Horibe, S.4    Fuseya, T.5    Tamaya, T.6
  • 285
    • 0033709497 scopus 로고    scopus 로고
    • A gonadotropin-releasing hormone-responsive phosphatase hydrolyses lysophosphatidic acid within the plasma membrane of ovarian cancer cells
    • Imai A, Furui T, Tamaya T, Mills GB 2000 A gonadotropin-releasing hormone-responsive phosphatase hydrolyses lysophosphatidic acid within the plasma membrane of ovarian cancer cells. J Clin Endocrinol Metab 85:3370-3375
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3370-3375
    • Imai, A.1    Furui, T.2    Tamaya, T.3    Mills, G.B.4
  • 286
    • 0036835799 scopus 로고    scopus 로고
    • GnRH agonist inhibits human telomerase reverse transcriptase mRNA expression in endometrial cancer cells
    • Nagai N, Oshita T, Mukai K, Shiroyama Y, Shigemasa K, Ohama K 2002 GnRH agonist inhibits human telomerase reverse transcriptase mRNA expression in endometrial cancer cells. Int J Mol Med 10:593-597
    • (2002) Int J Mol Med , vol.10 , pp. 593-597
    • Nagai, N.1    Oshita, T.2    Mukai, K.3    Shiroyama, Y.4    Shigemasa, K.5    Ohama, K.6
  • 287
    • 0038238317 scopus 로고    scopus 로고
    • Regulation of prostate-specific antigen gene expression by an LH-RH analogue in human prostatic cells
    • Sica G, Zelano G, Settesoldi D, Iacopino F 2003 Regulation of prostate-specific antigen gene expression by an LH-RH analogue in human prostatic cells. Anticancer Res 22:1283-1287
    • (2003) Anticancer Res , vol.22 , pp. 1283-1287
    • Sica, G.1    Zelano, G.2    Settesoldi, D.3    Iacopino, F.4
  • 288
    • 0036213910 scopus 로고    scopus 로고
    • Relationship between platelet-derived growth factor expression in leiomyomas and uterine volume changes after gonadotropin-releasing hormone agonist treatment
    • Di Lieto A, De Rosa G, De Falco M, Iannotti F, Staibano S, Pollio F, Scaramellino M, Salvatore G 2002 Relationship between platelet-derived growth factor expression in leiomyomas and uterine volume changes after gonadotropin-releasing hormone agonist treatment. Hum Pathol 33:220-224
    • (2002) Hum Pathol , vol.33 , pp. 220-224
    • Di Lieto, A.1    De Rosa, G.2    De Falco, M.3    Iannotti, F.4    Staibano, S.5    Pollio, F.6    Scaramellino, M.7    Salvatore, G.8
  • 289
    • 0035085112 scopus 로고    scopus 로고
    • Interleukin 8 production and interleukin 8 receptor expression in human myometrium and leiomyoma
    • Senturk LM, Sozen I, Gutierrez L, Arici A 2001 Interleukin 8 production and interleukin 8 receptor expression in human myometrium and leiomyoma. Am J Obstet Gynecol 184:559-566
    • (2001) Am J Obstet Gynecol , vol.184 , pp. 559-566
    • Senturk, L.M.1    Sozen, I.2    Gutierrez, L.3    Arici, A.4
  • 290
    • 0031777222 scopus 로고    scopus 로고
    • Cellular proliferation, estrogen receptor, progesterone receptor, and bcl-2 expression in GnRH agonist-treated uterine leiomyomas
    • Vu K, Greenspan DL, Wu TC, Zacur HA, Kurman RJ 1998 Cellular proliferation, estrogen receptor, progesterone receptor, and bcl-2 expression in GnRH agonist-treated uterine leiomyomas. Hum Pathol 29:359-363
    • (1998) Hum Pathol , vol.29 , pp. 359-363
    • Vu, K.1    Greenspan, D.L.2    Wu, T.C.3    Zacur, H.A.4    Kurman, R.J.5
  • 291
    • 0042135781 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone agonist induces apoptosis and reduces cell proliferation in eutopic endometrial cultures from women with endometriosis
    • Meresman GF, Bilotas M, Buquet RA, Baranao RI, Sueldo C, Tesone M 2003 Gonadotropin-releasing hormone agonist induces apoptosis and reduces cell proliferation in eutopic endometrial cultures from women with endometriosis. Fertil Steril 80:702-707
    • (2003) Fertil Steril , vol.80 , pp. 702-707
    • Meresman, G.F.1    Bilotas, M.2    Buquet, R.A.3    Baranao, R.I.4    Sueldo, C.5    Tesone, M.6
  • 292
    • 0032079723 scopus 로고    scopus 로고
    • Pathogenetic significance of increased levels of interleukin-8 in the peritoneal fluid of patients with endometriosis
    • Iwabe T, Harada T, Tsudo T, Tanikawa M, Onohara Y, Terakawa N 1998 Pathogenetic significance of increased levels of interleukin-8 in the peritoneal fluid of patients with endometriosis. Fertil Steril 69:924-930
    • (1998) Fertil Steril , vol.69 , pp. 924-930
    • Iwabe, T.1    Harada, T.2    Tsudo, T.3    Tanikawa, M.4    Onohara, Y.5    Terakawa, N.6
  • 293
    • 0034454647 scopus 로고    scopus 로고
    • Tumor necrosis factor-α promotes proliferation of endometriotic stromal cells by inducing interleukin-8 gene and protein expression
    • Iwabe T, Harada T, Tsudo T, Nagano Y, Yoshida S, Tanikawa M, Terakawa N 2000 Tumor necrosis factor-α promotes proliferation of endometriotic stromal cells by inducing interleukin-8 gene and protein expression. J Clin Endocrinol Metab 85:824-829
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 824-829
    • Iwabe, T.1    Harada, T.2    Tsudo, T.3    Nagano, Y.4    Yoshida, S.5    Tanikawa, M.6    Terakawa, N.7
  • 294
    • 0036182849 scopus 로고    scopus 로고
    • Expression of receptors for luteinizing hormone-releasing hormone in human ovarian and endometrial cancers: Frequency, autoregulation, and correlation with direct antiproliferative activity of luteinizing hormone-releasing hormone analogues
    • Volker P, Grundker C, Schmidt O, Schulz KD, Emons G 2002 Expression of receptors for luteinizing hormone-releasing hormone in human ovarian and endometrial cancers: frequency, autoregulation, and correlation with direct antiproliferative activity of luteinizing hormone-releasing hormone analogues. Am J Obstet Gynecol 186:171-179
    • (2002) Am J Obstet Gynecol , vol.186 , pp. 171-179
    • Volker, P.1    Grundker, C.2    Schmidt, O.3    Schulz, K.D.4    Emons, G.5
  • 295
    • 0027955120 scopus 로고
    • Gonadotropin-releasing hormone directly induces apoptotic cell death in the rat ovary: Biochemical and in situ detection of deoxyribonucleic acid fragmentation in granulosa cells
    • Billig H, Furuta I, Hsueh AJ 1994 Gonadotropin-releasing hormone directly induces apoptotic cell death in the rat ovary: biochemical and in situ detection of deoxyribonucleic acid fragmentation in granulosa cells. Endocrinology 134:245-252
    • (1994) Endocrinology , vol.134 , pp. 245-252
    • Billig, H.1    Furuta, I.2    Hsueh, A.J.3
  • 296
    • 0030811822 scopus 로고    scopus 로고
    • Effect of luteinizing hormone-releasing hormone analogs on the rat ovarian follicle development
    • Yano T, Yano N, Matsumi H, Morita Y, Tsutsumi O, Serially AV, Taketani Y 1997 Effect of luteinizing hormone-releasing hormone analogs on the rat ovarian follicle development. Horm Res 48:35-41
    • (1997) Horm Res , vol.48 , pp. 35-41
    • Yano, T.1    Yano, N.2    Matsumi, H.3    Morita, Y.4    Tsutsumi, O.5    Serially, A.V.6    Taketani, Y.7
  • 297
    • 0032840716 scopus 로고    scopus 로고
    • Mitochondrial peripheral-type benzodiazepine receptor expression.
    • Papadopoulos V, Dharmarajan AM, Li H, Culty M, Lemay M, Sridaran R 1999 Mitochondrial peripheral-type benzodiazepine receptor expression. Correlation with gonadotropin-releasing hormone (GnRH) agonist-induced apoptosis in the corpus luteum. Biochem Pharmacol 58:1389-1393
    • (1999) Biochem Pharmacol , vol.58 , pp. 1389-1393
    • Papadopoulos, V.1    Dharmarajan, A.M.2    Li, H.3    Culty, M.4    Lemay, M.5    Sridaran, R.6
  • 298
    • 0031732851 scopus 로고    scopus 로고
    • Evidence for tight coupling of gonadotropin-releasing hormone receptor to stimulated Fas ligand expression in reproductive tract tumors: Possible mechanism for hormonal control of apoptotic cell death
    • Imai A, Takagi A, Horibe S, Takagi H, Tamaya T 1998 Evidence for tight coupling of gonadotropin-releasing hormone receptor to stimulated Fas ligand expression in reproductive tract tumors: possible mechanism for hormonal control of apoptotic cell death. J Clin Endocrinol Metab 83:427-431
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 427-431
    • Imai, A.1    Takagi, A.2    Horibe, S.3    Takagi, H.4    Tamaya, T.5
  • 300
    • 0033756722 scopus 로고    scopus 로고
    • Luteinizing hormone-releasing hormone induces nuclear factor κB-activation and inhibits apoptosis in ovarian cancer cells
    • Grundker C, Schulz K, Gunthert AR, Emons G 2000 Luteinizing hormone-releasing hormone induces nuclear factor κB-activation and inhibits apoptosis in ovarian cancer cells. J Clin Endocrinol Metab 85:3815-3820
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3815-3820
    • Grundker, C.1    Schulz, K.2    Gunthert, A.R.3    Emons, G.4
  • 301
    • 0030885421 scopus 로고    scopus 로고
    • Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis C-IAP2 is under NF-κB control
    • Chu ZL, McKinsey TA, Liu L, Gentry JJ, Malim MH, Ballard DW 1997 Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis C-IAP2 is under NF-κB control. Proc Natl Acad Sci USA 94:10057-10062
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10057-10062
    • Chu, Z.L.1    McKinsey, T.A.2    Liu, L.3    Gentry, J.J.4    Malim, M.H.5    Ballard, D.W.6
  • 302
    • 0030707537 scopus 로고    scopus 로고
    • ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein
    • You M, Ku PT, Hrdlickova R, Bose Jr HR 1997 ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein. Mol Cell Biol 17: 7328-7341
    • (1997) Mol Cell Biol , vol.17 , pp. 7328-7341
    • You, M.1    Ku, P.T.2    Hrdlickova, R.3    Bose Jr., H.R.4
  • 303
    • 0032508414 scopus 로고    scopus 로고
    • NF-κB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and C-IAP2 to suppress caspase-8 activation
    • Wang CY, Mayo MW, Komeluk RG, Goeddel DV, Baldwin Jr AS 1998 NF-κB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and C-IAP2 to suppress caspase-8 activation. Science 281: 1680-1683
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.Y.1    Mayo, M.W.2    Komeluk, R.G.3    Goeddel, D.V.4    Baldwin Jr., A.S.5
  • 304
    • 0033558215 scopus 로고    scopus 로고
    • The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-κB that blocks TNFα-induced apoptosis
    • Zong WX, Edelstein LC, Chen C, Bash J, Gelinas C 1999 The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-κB that blocks TNFα-induced apoptosis. Genes Dev 13:382-387
    • (1999) Genes Dev , vol.13 , pp. 382-387
    • Zong, W.X.1    Edelstein, L.C.2    Chen, C.3    Bash, J.4    Gelinas, C.5
  • 305
    • 0034744033 scopus 로고    scopus 로고
    • NF-κB inducers upregulates cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling
    • Kreuz S, Siegmund D, Scheurich P, Wajant H 2001 NF-κB inducers upregulates cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling. Mol Cell Biol 21:3964-3973
    • (2001) Mol Cell Biol , vol.21 , pp. 3964-3973
    • Kreuz, S.1    Siegmund, D.2    Scheurich, P.3    Wajant, H.4
  • 307
    • 0031762899 scopus 로고    scopus 로고
    • Suppression of cell proliferation and induction of apoptosis in uterine leiomyoma by gonadotropin-releasing hormone agonist (leuprolide acetate)
    • Mizutani T, Sugihara A, Nakamuro K, Terada N 1998 Suppression of cell proliferation and induction of apoptosis in uterine leiomyoma by gonadotropin-releasing hormone agonist (leuprolide acetate). J Clin Endocrinol Metab 83:1253-1255
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1253-1255
    • Mizutani, T.1    Sugihara, A.2    Nakamuro, K.3    Terada, N.4
  • 308
    • 0036204393 scopus 로고    scopus 로고
    • Down-regulation of proliferation and up-regulation of apoptosis by gonadotropin-releasing hormone agonist in cultured uterine leiomyoma cells
    • Wang Y, Matsuo H, Kurachi O, Maruo T 2002 Down-regulation of proliferation and up-regulation of apoptosis by gonadotropin-releasing hormone agonist in cultured uterine leiomyoma cells. Eur J Endocrinol 146:447-456
    • (2002) Eur J Endocrinol , vol.146 , pp. 447-456
    • Wang, Y.1    Matsuo, H.2    Kurachi, O.3    Maruo, T.4
  • 309
    • 0030929479 scopus 로고    scopus 로고
    • Enhanced deoxyribonucleic acid damage and repair but unchanged apoptosis in uterine leiomyomas treated with gonadotropin-releasing hormone agonist
    • Huang SC, Chou CY, Lin YS, Tsai YC, Hsu KF, Liu CH, Huang KE 1997 Enhanced deoxyribonucleic acid damage and repair but unchanged apoptosis in uterine leiomyomas treated with gonadotropin-releasing hormone agonist. Am J Obstet Gynecol 177:417-424
    • (1997) Am J Obstet Gynecol , vol.177 , pp. 417-424
    • Huang, S.C.1    Chou, C.Y.2    Lin, Y.S.3    Tsai, Y.C.4    Hsu, K.F.5    Liu, C.H.6    Huang, K.E.7
  • 310
    • 0036775167 scopus 로고    scopus 로고
    • Fas and its ligand, caspases, and bcl-2 expression in gonadotropin-releasing hormone agonist-treated uterine leiomyoma
    • Huang SC, Tang MJ, Hsu KF, Cheng YM, Chou CY 2002 Fas and its ligand, caspases, and bcl-2 expression in gonadotropin-releasing hormone agonist-treated uterine leiomyoma. J Clin Endocrinol Metab 87:4580-4586
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 4580-4586
    • Huang, S.C.1    Tang, M.J.2    Hsu, K.F.3    Cheng, Y.M.4    Chou, C.Y.5
  • 311
    • 0034123428 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone analog repairs reduced endometrial cell apoptosis in endometriosis in vitro
    • Imai A, Takagi A, Tamaya T 2000 Gonadotropin-releasing hormone analog repairs reduced endometrial cell apoptosis in endometriosis in vitro. Am J Obstet Gynecol 182:1142-1146
    • (2000) Am J Obstet Gynecol , vol.182 , pp. 1142-1146
    • Imai, A.1    Takagi, A.2    Tamaya, T.3
  • 312
    • 0043265128 scopus 로고    scopus 로고
    • Effect of GnRH analogues on apoptosis and release of interleukin-1β and vascular endothelial growth factor in endometrial cell cultures from patients with endometriosis
    • Meresman GF, Bilotas MA, Lombardi E, Tesone M, Sueldo C, Baranao RI 2003 Effect of GnRH analogues on apoptosis and release of interleukin-1β and vascular endothelial growth factor in endometrial cell cultures from patients with endometriosis. Hum Reprod 18:1767-1771
    • (2003) Hum Reprod , vol.18 , pp. 1767-1771
    • Meresman, G.F.1    Bilotas, M.A.2    Lombardi, E.3    Tesone, M.4    Sueldo, C.5    Baranao, R.I.6
  • 313
    • 0029065072 scopus 로고
    • The signals and molecular pathways involved in implantation, a symbiotic interaction between blastocyst and endometrium involving adhesion and tissue invasion
    • Tabibzadeh S, Babaknia A 1995 The signals and molecular pathways involved in implantation, a symbiotic interaction between blastocyst and endometrium involving adhesion and tissue invasion. Hum Reprod 10:1579-1602
    • (1995) Hum Reprod , vol.10 , pp. 1579-1602
    • Tabibzadeh, S.1    Babaknia, A.2
  • 314
    • 0037150686 scopus 로고    scopus 로고
    • Deciphering the cross-talk of implantation: Advances and challenges
    • Paria BC, Reese J, Das SK, Dey SK 2002 Deciphering the cross-talk of implantation: advances and challenges. Science 296:2185-2188
    • (2002) Science , vol.296 , pp. 2185-2188
    • Paria, B.C.1    Reese, J.2    Das, S.K.3    Dey, S.K.4
  • 315
    • 0035931010 scopus 로고    scopus 로고
    • GnRH agonist Buserelin affects colony-forming efficiency of HHUA and Jurkat cells
    • Enomoto M, Mori T, Park MK 2001 GnRH agonist Buserelin affects colony-forming efficiency of HHUA and Jurkat cells. Biochem Biophys Res Commun 289:1180-1187
    • (2001) Biochem Biophys Res Commun , vol.289 , pp. 1180-1187
    • Enomoto, M.1    Mori, T.2    Park, M.K.3
  • 316
    • 0033857735 scopus 로고    scopus 로고
    • Immunoidentification of gonadotropin releasing hormone receptor in human sperm, pituitary and cancer cells
    • Lee CY, Ho J, Chow SN, Yasojima K, Schwab C, McGeer PL 2000 Immunoidentification of gonadotropin releasing hormone receptor in human sperm, pituitary and cancer cells. Am J Reprod Immunol 44:170-177
    • (2000) Am J Reprod Immunol , vol.44 , pp. 170-177
    • Lee, C.Y.1    Ho, J.2    Chow, S.N.3    Yasojima, K.4    Schwab, C.5    McGeer, P.L.6
  • 317
    • 0033874294 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone-stimulated sperm binding to the human zona is mediated by a calcium influx
    • Morales P, Pizarro E, Kong M, Kerr B, Ceric F, Vigil P 2000 Gonadotropin-releasing hormone-stimulated sperm binding to the human zona is mediated by a calcium influx. Biol Reprod 63:635-642
    • (2000) Biol Reprod , vol.63 , pp. 635-642
    • Morales, P.1    Pizarro, E.2    Kong, M.3    Kerr, B.4    Ceric, F.5    Vigil, P.6
  • 320
    • 0034810482 scopus 로고    scopus 로고
    • A gonadotropin-releasing hormone (GnRH) receptor specific for GnRH II in primates
    • Neill JD, Duck LW, Sellers JC, Musgrove LC 2001 A gonadotropin-releasing hormone (GnRH) receptor specific for GnRH II in primates. Biochem Biophys Res Commun 282:1012-1018
    • (2001) Biochem Biophys Res Commun , vol.282 , pp. 1012-1018
    • Neill, J.D.1    Duck, L.W.2    Sellers, J.C.3    Musgrove, L.C.4
  • 323
    • 0033515025 scopus 로고    scopus 로고
    • Two gonadotropin-releasing hormone receptor subtypes with distinct ligand selectivity and differential distribution in brain and pituitary in the goldfish (Carassius auratus)
    • Illing N, Troskie BE, Nahorniak CS, Hapgood JP, Peter RE, Millar RP 1999 Two gonadotropin-releasing hormone receptor subtypes with distinct ligand selectivity and differential distribution in brain and pituitary in the goldfish (Carassius auratus). Proc Natl Acad Sci USA 96:2526-2531
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2526-2531
    • Illing, N.1    Troskie, B.E.2    Nahorniak, C.S.3    Hapgood, J.P.4    Peter, R.E.5    Millar, R.P.6
  • 324
    • 0034456241 scopus 로고    scopus 로고
    • Complementary deoxyribonucleic acid cloning, gene expression, and ligand selectivity of a novel gonadotropin-releasing hormone receptor expressed in the pituitary and midbrain of Xenopus laevis
    • Troskie BE, Hapgood JP, Millar RP, Illing N 2000 Complementary deoxyribonucleic acid cloning, gene expression, and ligand selectivity of a novel gonadotropin-releasing hormone receptor expressed in the pituitary and midbrain of Xenopus laevis. Endocrinology 141:1764-1771
    • (2000) Endocrinology , vol.141 , pp. 1764-1771
    • Troskie, B.E.1    Hapgood, J.P.2    Millar, R.P.3    Illing, N.4
  • 327
    • 0022981014 scopus 로고
    • Desensitization to gonadotropin-releasing hormone in perifused chicken anterior pituitary cells
    • King JA, Davidson JS, Millar RP 1986 Desensitization to gonadotropin-releasing hormone in perifused chicken anterior pituitary cells. Endocrinology 119:1510-1518
    • (1986) Endocrinology , vol.119 , pp. 1510-1518
    • King, J.A.1    Davidson, J.S.2    Millar, R.P.3
  • 329
    • 85047684264 scopus 로고    scopus 로고
    • GnRH and GnRH receptor genes in the human genome
    • Neill JD 2002 GnRH and GnRH receptor genes in the human genome. Endocrinology 143:737-743
    • (2002) Endocrinology , vol.143 , pp. 737-743
    • Neill, J.D.1
  • 330
    • 0041920691 scopus 로고    scopus 로고
    • Multiple determinants for rapid agonist-induced internalization of a nonmammalian gonadotropin-releasing hormone receptor: A putative palmitoylation site and threonine doublet within the carboxyl-terminal tail are critical
    • Pawson AJ, Maudsley SR, Lopes J, Katz AA, Sun YM, Davidson JS, Millar RP 2003 Multiple determinants for rapid agonist-induced internalization of a nonmammalian gonadotropin-releasing hormone receptor: a putative palmitoylation site and threonine doublet within the carboxyl-terminal tail are critical. Endocrinology 144:3860-3871
    • (2003) Endocrinology , vol.144 , pp. 3860-3871
    • Pawson, A.J.1    Maudsley, S.R.2    Lopes, J.3    Katz, A.A.4    Sun, Y.M.5    Davidson, J.S.6    Millar, R.P.7
  • 331
    • 0032230140 scopus 로고    scopus 로고
    • Addition of catfish gonadotropin-releasing hormone (GnRH) receptor intracellular carboxyl-terminal tail to rat GnRH receptor alters receptor expression and regulation
    • Lin X, Janovick JA, Brothers S, Blomenrohr M, Bogerd J, Conn PM 1998 Addition of catfish gonadotropin-releasing hormone (GnRH) receptor intracellular carboxyl-terminal tail to rat GnRH receptor alters receptor expression and regulation. Mol Endocrinol 12:161-171
    • (1998) Mol Endocrinol , vol.12 , pp. 161-171
    • Lin, X.1    Janovick, J.A.2    Brothers, S.3    Blomenrohr, M.4    Bogerd, J.5    Conn, P.M.6
  • 332
    • 0345045562 scopus 로고    scopus 로고
    • Pivotal role for the cytoplasmic carboxyl-terminal tail of a nonmammalian gonadotropin-releasing hormone receptor in cell surface expression, ligand binding, and receptor phosphorylation and internalization
    • Blomenrohr M, Heding A, Sellar R, Leurs R, Bogerd J, Eidne KA, Willars GB 1999 Pivotal role for the cytoplasmic carboxyl-terminal tail of a nonmammalian gonadotropin-releasing hormone receptor in cell surface expression, ligand binding, and receptor phosphorylation and internalization. Mol Pharmacol 56:12229-12237
    • (1999) Mol Pharmacol , vol.56 , pp. 12229-12237
    • Blomenrohr, M.1    Heding, A.2    Sellar, R.3    Leurs, R.4    Bogerd, J.5    Eidne, K.A.6    Willars, G.B.7
  • 334
    • 0028100755 scopus 로고
    • Glutamate 301 of the mouse gonadotropin-releasing hormone receptor confers specificity for arginine 8 of mammalian gonadotropin-releasing hormone
    • Flanagan CA, Becker II, Davidson JS, Wakefield IK, Zhou W, Sealfon SC, Millar RP 1994 Glutamate 301 of the mouse gonadotropin-releasing hormone receptor confers specificity for arginine 8 of mammalian gonadotropin-releasing hormone. J Biol Chem 269:22636-22641
    • (1994) J Biol Chem , vol.269 , pp. 22636-22641
    • Flanagan, C.A.1    Becker, I.I.2    Davidson, J.S.3    Wakefield, I.K.4    Zhou, W.5    Sealfon, S.C.6    Millar, R.P.7
  • 335
    • 0028203309 scopus 로고
    • Inhibition of human epithelial ovarian cancer cell growth in vitro by agonistic and antagonistic analogues of luteinizing hormone-releasing hormone
    • Yano T, Pinski J, Radulovic S, Schally AV 1994 Inhibition of human epithelial ovarian cancer cell growth in vitro by agonistic and antagonistic analogues of luteinizing hormone-releasing hormone. Proc Natl Acad Sci USA 91:1701-1704 336.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 1701-1704
    • Yano, T.1    Pinski, J.2    Radulovic, S.3    Schally, A.V.4
  • 338
    • 0037320294 scopus 로고    scopus 로고
    • A transcriptionally active human type II gonadotropin-releasing hormone receptor gene homolog overlaps two genes in the antisense orientation on chromosome 1q. 12
    • Morgan K, Conklin D, Pawson AJ, Sellar R, Ott TR, Millar RP 2003 A transcriptionally active human type II gonadotropin-releasing hormone receptor gene homolog overlaps two genes in the antisense orientation on chromosome 1q. 12. Endocrinology 144:423-436
    • (2003) Endocrinology , vol.144 , pp. 423-436
    • Morgan, K.1    Conklin, D.2    Pawson, A.J.3    Sellar, R.4    Ott, T.R.5    Millar, R.P.6
  • 340
    • 0141613856 scopus 로고    scopus 로고
    • Type II gonadotropin-releasing hormone (GnRH-II) in reproductive biology
    • Pawson AJ, Morgan K, Maudsley SR, Millar RP 2003 Type II gonadotropin-releasing hormone (GnRH-II) in reproductive biology. Reproduction 126:271-278
    • (2003) Reproduction , vol.126 , pp. 271-278
    • Pawson, A.J.1    Morgan, K.2    Maudsley, S.R.3    Millar, R.P.4
  • 341
    • 2042478034 scopus 로고    scopus 로고
    • Sheep exhibit novel variations in the organization of the mammalian type II gonadotropin-releasing hormone receptor gene
    • Gault PM, Morgan K, Pawson AJ, Millar RP, Lincoln GA 2004 Sheep exhibit novel variations in the organization of the mammalian type II gonadotropin-releasing hormone receptor gene. Endocrinology 145:2362-2374
    • (2004) Endocrinology , vol.145 , pp. 2362-2374
    • Gault, P.M.1    Morgan, K.2    Pawson, A.J.3    Millar, R.P.4    Lincoln, G.A.5
  • 342
    • 0034756120 scopus 로고    scopus 로고
    • The genes encoding the type II gonadotropin-releasing hormone receptor and the ribonucleoprotein RBM8A in humans overlap in two genomic loci
    • Faurholm B, Millar RP, Katz AA 2001 The genes encoding the type II gonadotropin-releasing hormone receptor and the ribonucleoprotein RBM8A in humans overlap in two genomic loci. Genomics 78:15-18
    • (2001) Genomics , vol.78 , pp. 15-18
    • Faurholm, B.1    Millar, R.P.2    Katz, A.A.3
  • 343
    • 0034306703 scopus 로고    scopus 로고
    • Identification and structural analysis of human RBM8A and RBM8B: Two highly conserved RNA-binding motif proteins that interact with OVCA1, a candidate tumor suppressor
    • Salicioni AM, Xi M, Vanderveer LA, Balsara B, Testa JR, Dunbrack Jr RL, Godwin AK 2000 Identification and structural analysis of human RBM8A and RBM8B: two highly conserved RNA-binding motif proteins that interact with OVCA1, a candidate tumor suppressor. Genomics 69:54-62
    • (2000) Genomics , vol.69 , pp. 54-62
    • Salicioni, A.M.1    Xi, M.2    Vanderveer, L.A.3    Balsara, B.4    Testa, J.R.5    Dunbrack Jr., R.L.6    Godwin, A.K.7
  • 344
    • 1842831523 scopus 로고    scopus 로고
    • Type II gonadotropin-releasing hormone receptor transcripts in human sperm
    • van Biljon W, Wykes S, Scherer S, Krawetz SA, Hapgood J 2002 Type II gonadotropin-releasing hormone receptor transcripts in human sperm. Biol Reprod 67:1741-1749
    • (2002) Biol Reprod , vol.67 , pp. 1741-1749
    • Van Biljon, W.1    Wykes, S.2    Scherer, S.3    Krawetz, S.A.4    Hapgood, J.5
  • 345
    • 0033529257 scopus 로고    scopus 로고
    • Five-transmembrane domains appear sufficient for a G protein-coupled receptor: Functional five-transmembrane domain chemokine receptors
    • Ling K, Wang P, Zhao J, Wu YL, Cheng ZJ, Ubi GX, Hu W, Ma L, Pei G 1999 Five-transmembrane domains appear sufficient for a G protein-coupled receptor: functional five-transmembrane domain chemokine receptors. Proc Natl Acad Sci USA 96:7922-7927
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 7922-7927
    • Ling, K.1    Wang, P.2    Zhao, J.3    Wu, Y.L.4    Cheng, Z.J.5    Ubi, G.X.6    Hu, W.7    Ma, L.8    Pei, G.9
  • 347
    • 0034723169 scopus 로고    scopus 로고
    • Structural implication for receptor oligomerization from functional reconstitution studies of mutant V2 vasopressin receptors
    • Schultz A, Groose R, Schultz G, Gudermann T, Schoneberg T 2000 Structural implication for receptor oligomerization from functional reconstitution studies of mutant V2 vasopressin receptors. J Biol Chem 275:2381-2389
    • (2000) J Biol Chem , vol.275 , pp. 2381-2389
    • Schultz, A.1    Groose, R.2    Schultz, G.3    Gudermann, T.4    Schoneberg, T.5
  • 348
    • 0034928729 scopus 로고    scopus 로고
    • Mammalian selenium-containing proteins
    • Behne D, Kyriakopoulos A 2001 Mammalian selenium-containing proteins. Annu Rev Nutr 21:453-473
    • (2001) Annu Rev Nutr , vol.21 , pp. 453-473
    • Behne, D.1    Kyriakopoulos, A.2
  • 349
    • 0141541812 scopus 로고    scopus 로고
    • Regulation of gene expression by stop codon receding: Selenocysteine
    • Copeland PR 2003 Regulation of gene expression by stop codon receding: selenocysteine. Gene 312:17-25
    • (2003) Gene , vol.312 , pp. 17-25
    • Copeland, P.R.1
  • 350
    • 0032561359 scopus 로고    scopus 로고
    • UGA codon position affects the efficiency of selenocysteine incorporation into glutathione peroxidase-1
    • Wen W, Weiss SL, Sunde RA 1998 UGA codon position affects the efficiency of selenocysteine incorporation into glutathione peroxidase-1. J Biol Chem 273:28533-28541
    • (1998) J Biol Chem , vol.273 , pp. 28533-28541
    • Wen, W.1    Weiss, S.L.2    Sunde, R.A.3
  • 351
    • 0042477742 scopus 로고    scopus 로고
    • Activation and nuclear translocation of PKCδ, Pyk2 and ERK1/2 by gonadotropin-releasing hormone in HEK293 cells
    • Farshori PQ, Shah BH, Arora KK, Martinez-Fuentes A, Catt KJ 2003 Activation and nuclear translocation of PKCδ, Pyk2 and ERK1/2 by gonadotropin-releasing hormone in HEK293 cells. J Steroid Biochem Mol Biol 85:337-347
    • (2003) J Steroid Biochem Mol Biol , vol.85 , pp. 337-347
    • Farshori, P.Q.1    Shah, B.H.2    Arora, K.K.3    Martinez-Fuentes, A.4    Catt, K.J.5
  • 352
    • 0345826089 scopus 로고    scopus 로고
    • Cytoskeleton reorganization dependence of signaling by the gonadotropin-releasing hormone receptor
    • Davidson L, Pawson AJ, Millar RP, Maudsley S 2004 Cytoskeleton reorganization dependence of signaling by the gonadotropin-releasing hormone receptor. J Biol Chem 279:1980-1993
    • (2004) J Biol Chem , vol.279 , pp. 1980-1993
    • Davidson, L.1    Pawson, A.J.2    Millar, R.P.3    Maudsley, S.4
  • 353
    • 1642564476 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone-induced activation of diacylglycerol kinase-ζ and its association with active c-src
    • Davidson L, Pawson AJ, De Maturana RL, Freestone SH, Barran P, Millar RP, Maudsley S 2004 Gonadotropin-releasing hormone-induced activation of diacylglycerol kinase-ζ and its association with active c-src. J Biol Chem 279:11906-11916
    • (2004) J Biol Chem , vol.279 , pp. 11906-11916
    • Davidson, L.1    Pawson, A.J.2    De Maturana, R.L.3    Freestone, S.H.4    Barran, P.5    Millar, R.P.6    Maudsley, S.7


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