The functional microdomain in transmembrane helices 2 and 7 regulates expression, activation, and coupling pathways of the gonadotropin-releasing hormone receptor

Journal of Biological Chemistry

Volumn 274, Issue 41, 1999, Pages 28880-28886

  Flanagan, Colleen A ^a   Zhou, Wei ^a   Chi, Ling ^a   Yuen, Tony ^a   Rodic, Vladimir ^a   Robertson, Derek ^b   Johnson, Melanie ^b,d   Holland, Pamela ^b   Millar, Robert P ^c,e   Weinstein, Harel ^a   Mitchell, Rory ^b,d   Sealfon, Stuart C ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b Med Res Cncl Brain Metab Unit   (United Kingdom)

^c UNIVERSITY OF CAPE TOWN   (South Africa)

^d Dept of Biomedical Sciences   (United Kingdom)

^e UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GONADORELIN RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHOLIPASE C;

AMINO ACID SEQUENCE; ARTICLE; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENE MUTATION; HORMONE RECEPTOR INTERACTION; IMMUNOBLOTTING; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0032879688     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.41.28880     Document Type: Article

References (37)

1. Sealfon, S. C., Weinstein, H., and Millar, R. P. (1997) Endocr. Rev. 18, 180-205
2. Baldwin, J. M. (1993) EMBO J. 12, 1693-1703
3. Probst, W. C., Snyder, L. A., Schuster, D. I., Brosius, J., and Sealfon, S. C. (1992) DNA Cell Biol. 11, 1-20
4. Ballesteros, J., Kitanovic, S., Guarnieri, F., Davies, P., Fromme, B. J., Konvicka, K., Chi, L., Millar, R. P., Davidson, J. S., Weinstein, H., and Sealfon, S. C. (1998) J. Biol. Chem. 273, 10445-10453
5. Schertler, G. F., Villa, C., and Henderson, R. (1993) Nature 362, 770-772
6. Schertler, G. F., and Hargrave, P. A. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 11578-11582
7. Ballesteros, J., and Weinstein, W. (1995) Methods Neurosci. 25, 366-428
8. Zhou, W., Flanagan, C., Ballesteros, J. A., Konvicka, K., Davidson, J. S., Weinstein, H., Millar, R. P., and Sealfon, S. C. (1994) Mol. Pharmacol. 45, 165-170
9. Sealfon, S. C., Chi, L., Ebersole, B. J., Rodic, V., Zhang, D., Ballesteros, J. A., and Weinstein, H. (1995) J. Biol. Chem. 270, 16683-16688
10. Perlman, J. H., Colson, A.-O., Wang, W., Bence, K., Osman, R., and Gershengorn, M. C. (1997) J. Biol. Chem. 272, 11937-11942
11. Xu, W., Ozdener, F., Li, J., Chen, C., de Riel, J., Weinstein, H., and Liu-Chen, L. (1999) FEBS Lett. 447, 318-324
12. Donnelly, D., Maudsley, S., Gent, J. P., Moser, R. N., Hurrell, C. R., and Findlay, J. B. (1999) Biochem. J. 339, 55-61
13. Cook, J. V., Faccenda, E., Anderson, L., Couper, G. G., Eidne, K. A., and Taylor, P. L. (1993) J. Endocrinol. 139, R1-4
14. Jagerschmidt, A., Guillaume, N., Goudreau, N., Maigret, B., and Roques, B. (1995) Mol. Pharmacol. 48, 783-789
15. Blomenrohr, M., Bogerd, J., Leurs, R., Schulz, R. W., Tensen, C. P., Zandbergen, M. A., and Goos, H. J. (1997) Biochem. Biophys. Res. Commun. 238, 517-522
16. Illing, N., Troskie, B., Nahorniak, C., Hapgood, J., Peter, R., and Millar, R. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 2526-2531
17. Barak, L. S., Menard, L., Ferguson, S. S., Colapietro, A. M., and Caron, M. G. (1995) Biochemistry 34, 15407-15414
18. Konvicka, K., Guarnieri, F., Ballesteros, J., and Weinstein, H. (1998) Biophys. J. 75, 601-611
19. Mitchell, R., McCulloch, D., Lutz, E., Johnson, M., MacKenzie, C., Fennell, M., Fink, G., Zhou, W., and Sealfon, S. (1998) Nature 392, 411-414
20. Millar, R., Conklin, D., Lofton-Day, C., Hutchinson, E., Troskie, B., Illing, N., Sealfon, S. C., and Hapgood, J. (1999) J. Endocrinol. 162, 117-126
21. Zhou, W., Rodic, V., Kitanovic, S., Flanagan, C. A., Chi, L., Weinstein, H., Maayani, S., Millar, R. P., and Sealfon, S. C. (1995) J. Biol. Chem. 270, 18853-18857
22. Laws, S. C., Beggs, M. J., Webster, J. C., and Miller, W. L. (1990) Endocrinology 127, 373-380
23. Sealfon, S., Zhou, W., Almaula, N., and Rodic, V. (1996) Methods Neurosci. 29, 143-196
24. Millar, R. P., Davidson, J., Flanagan, C. A., and Wakefield, I. (1995) Methods in Neurosciences, Receptor Molecular Biology, pp. 145-162, Academic Press, San Diego
25. Berg, K. A., Clarke, W. P., Sailstad, C., Saltzman, A., and Maayani, S. (1994) Mol. Pharmacol. 46, 477-484
26. Mitchell, R., Wolbers, W. B., Sim, P., and Fennell, M. (1995) Biochem. Soc. Trans. 23, 208S
27. Munson, P. J., and Rodbard, D. (1980) Anal. Biochem. 107, 220-239
28. Davidson, J. S., Assefa, D., Pawson, A., Davies, P., Hapgood, J., Becker, I., Flanagan, C., Roeske, R., and Millar, R. (1997) Biochemistry 36, 12881-12889
29. Suryanarayana, S., Daunt, D. A., Von Zastrow, M., and Kobilka, B. K. (1991) J. Biol. Chem. 266, 15488-15492
30. Gether, U., Ballesteros, J. A., Seifert, R., Sanders-Bush, E., Weinstein, H., and Kobilka, B. K. (1997) J. Biol. Chem. 272, 2587-2590
31. van Rhee, A. M., and Jacobson, K. A. (1996) Drug Dev. Res. 37, 1-38
32. Harrison, R. W., and Weber, I. T. (1994) Protein Eng. 7, 1353-1363
33. Davies, D. R. (1990) Annu. Rev. Biophys. Biophys. Chem. 19, 189-215
34. Scheer, A., Fanelli, F., Costa, T., De Benedetti, P., and Cotecchia, S. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 808-813
35. Hunyady, L., Bor, M., Baukal, A. J., Balla, T., and Catt, K. J. (1995) J. Biol. Chem. 270, 16602-16609
36. Parent, J.-L., Le Gouill, C., Escher, E., Rola-Pleszczynski, M., and Stakova, J. (1996) J. Biol. Chem. 271, 23298-23303
37. Surprenant, A., Horstman, D. A., Akbarali, H., and Limbird, L. E. (1992) Science 257, 977-980