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Volumn 11, Issue 12, 1997, Pages 1814-1821

The tripartite basal enhancer of the gonadotropin-releasing hormone (GnRH) receptor gene promoter regulates cell-specific expression through a novel GnRH receptor activating sequence

Author keywords

[No Author keywords available]

Indexed keywords

GONADORELIN; GONADORELIN RECEPTOR; THYMIDINE KINASE; TRANSCRIPTION FACTOR AP 1;

EID: 0030666563     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.11.12.0020     Document Type: Article
Times cited : (74)

References (38)
  • 1
    • 0025286831 scopus 로고
    • Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors
    • Simmons DM, Voss JW, Ingraham HA, Holloway JM, Broide RS, Rosenfeld MG, Swanson LW 1990 Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors. Genes Dev 4:695-711
    • (1990) Genes Dev , vol.4 , pp. 695-711
    • Simmons, D.M.1    Voss, J.W.2    Ingraham, H.A.3    Holloway, J.M.4    Broide, R.S.5    Rosenfeld, M.G.6    Swanson, L.W.7
  • 2
    • 0026799459 scopus 로고
    • Gonadotrope- and thyrotrope-specific expression of the human and bovine glycoprotein hormone α-subunit genes is regulated by distinct cis-acting elements
    • Hamernik DL, Keri RA, Clay CM, Clay JN, Sherman GB, Sawyer Jr HR, Nett TM, Nilson JH 1992 Gonadotrope- and thyrotrope-specific expression of the human and bovine glycoprotein hormone α-subunit genes is regulated by distinct cis-acting elements. Mol Endocrinol 6:1745-1755
    • (1992) Mol Endocrinol , vol.6 , pp. 1745-1755
    • Hamernik, D.L.1    Keri, R.A.2    Clay, C.M.3    Clay, J.N.4    Sherman, G.B.5    Sawyer Jr., H.R.6    Nett, T.M.7    Nilson, J.H.8
  • 4
    • 0025248506 scopus 로고
    • Cell lines of the pituitary gonadotrope lineage derived by target oncogenesis in transgenic mice
    • Windle JJ, Weiner RI, Mellon PL 1990 Cell lines of the pituitary gonadotrope lineage derived by target oncogenesis in transgenic mice. Mol Endocrinol 4:597-603
    • (1990) Mol Endocrinol , vol.4 , pp. 597-603
    • Windle, J.J.1    Weiner, R.I.2    Mellon, P.L.3
  • 5
    • 0026752378 scopus 로고
    • Analysis of DNA sequences required for pituitary-specific expression of the glycoprotein hormone α-subunit gene
    • Schoderbek WE, Kim KE, Ridgway EC, Mellon PL, Maurer RA 1992 Analysis of DNA sequences required for pituitary-specific expression of the glycoprotein hormone α-subunit gene. Mol Endocrinol 6:893-903
    • (1992) Mol Endocrinol , vol.6 , pp. 893-903
    • Schoderbek, W.E.1    Kim, K.E.2    Ridgway, E.C.3    Mellon, P.L.4    Maurer, R.A.5
  • 6
    • 0028203766 scopus 로고
    • Activation of the glycoprotein hormone alpha subunit promoter by a LIM-homeodomain transcription factor
    • Roberson MS, Schoderbek WE, Tremml G, Maurer RA 1994 Activation of the glycoprotein hormone alpha subunit promoter by a LIM-homeodomain transcription factor. Mol Cell Biol 14:2985-2993
    • (1994) Mol Cell Biol , vol.14 , pp. 2985-2993
    • Roberson, M.S.1    Schoderbek, W.E.2    Tremml, G.3    Maurer, R.A.4
  • 7
    • 0028783348 scopus 로고
    • Different composite regulatory elements direct expression of the human α subunit gene to pituitary and placenta
    • Heckert LL, Schultz K, Nilson JH 1995 Different composite regulatory elements direct expression of the human α subunit gene to pituitary and placenta. J Biol Chem 270:26497-26504
    • (1995) J Biol Chem , vol.270 , pp. 26497-26504
    • Heckert, L.L.1    Schultz, K.2    Nilson, J.H.3
  • 8
    • 0028898942 scopus 로고
    • Upstream stimulatory factor, a basic-helix-loop-helix-zipper protein, regulates the activity of the α-glycoprotein hormone subunit gene in pituitary cells
    • Jackson SM, Gutierrez-Hartmann A, Hoeffler JP 1995 Upstream stimulatory factor, a basic-helix-loop-helix-zipper protein, regulates the activity of the α-glycoprotein hormone subunit gene in pituitary cells. Mol Endocrinol 9:278-291
    • (1995) Mol Endocrinol , vol.9 , pp. 278-291
    • Jackson, S.M.1    Gutierrez-Hartmann, A.2    Hoeffler, J.P.3
  • 9
    • 0028136164 scopus 로고
    • GATA-binding proteins regulate the human gonadotropin α-subunit gene in the placenta and pituitary gland
    • Steger DJ, Hecht JH, Mellon PL 1994 GATA-binding proteins regulate the human gonadotropin α-subunit gene in the placenta and pituitary gland. Mol Cell Biol 14:5592-5602
    • (1994) Mol Cell Biol , vol.14 , pp. 5592-5602
    • Steger, D.J.1    Hecht, J.H.2    Mellon, P.L.3
  • 10
    • 0026693316 scopus 로고
    • Tissue-specific gene expression in the pituitary: The glycoprotein hormone α-subunit gene is regulated by a gonadotrope-specific protein
    • Horn F, Windle JJ, Barnhart KM, Mellon PM 1992 Tissue-specific gene expression in the pituitary: the glycoprotein hormone α-subunit gene is regulated by a gonadotrope-specific protein. Mol Cell Biol 12:2143-2153
    • (1992) Mol Cell Biol , vol.12 , pp. 2143-2153
    • Horn, F.1    Windle, J.J.2    Barnhart, K.M.3    Mellon, P.M.4
  • 11
    • 0028365295 scopus 로고
    • The orphan nuclear receptor steroidogenic factor-1, regulates the glycoprotein hormone α-subunit gene in pituitary gonadotropes
    • Barnhart KM, Mellon PL 1994 The orphan nuclear receptor steroidogenic factor-1, regulates the glycoprotein hormone α-subunit gene in pituitary gonadotropes. Mol Endocrinol 8:878-885
    • (1994) Mol Endocrinol , vol.8 , pp. 878-885
    • Barnhart, K.M.1    Mellon, P.L.2
  • 12
    • 0023261937 scopus 로고
    • Cyclic AMP responsiveness of human gonadotropin-α gene transcription is directed by a repeated 18-base pair enhancer: α-promoter receptivity to the enhancer confers cell-preferential expression
    • Deutsch PJ, Jameson JL, Habener JF 1987 Cyclic AMP responsiveness of human gonadotropin-α gene transcription is directed by a repeated 18-base pair enhancer: α-promoter receptivity to the enhancer confers cell-preferential expression. J Biol Chem 262:12169-12174
    • (1987) J Biol Chem , vol.262 , pp. 12169-12174
    • Deutsch, P.J.1    Jameson, J.L.2    Habener, J.F.3
  • 13
    • 0023446832 scopus 로고
    • Tissue-specific enhancer of the human glycoprotein hormone alpha-subunit gene: Dependence on cyclic AMP-inducible elements
    • Delegeane AM, Ferland LH, Mellon PL 1987 Tissue-specific enhancer of the human glycoprotein hormone alpha-subunit gene: dependence on cyclic AMP-inducible elements. Mol Cell Biol 7:3994-4002
    • (1987) Mol Cell Biol , vol.7 , pp. 3994-4002
    • Delegeane, A.M.1    Ferland, L.H.2    Mellon, P.L.3
  • 14
    • 0029856393 scopus 로고    scopus 로고
    • The cAMP response elements of the a subunit gene bind similar proteins in trophoblasts and gonadotropes but have distinct functional sequence requirements
    • Heckert LL, Schultz K, Nilson JH 1996 The cAMP response elements of the a subunit gene bind similar proteins in trophoblasts and gonadotropes but have distinct functional sequence requirements. J Biol Chem 271:31650-31656
    • (1996) J Biol Chem , vol.271 , pp. 31650-31656
    • Heckert, L.L.1    Schultz, K.2    Nilson, J.H.3
  • 15
    • 0030002926 scopus 로고    scopus 로고
    • Stimulation of luteinizing hormone β gene promoter activity by the orphan nuclear receptor, steroidogenic factor-1
    • Halvorson LM, Kaiser UB, Chin WW 1996 Stimulation of luteinizing hormone β gene promoter activity by the orphan nuclear receptor, steroidogenic factor-1. J Biol Chem 271:6645-6650
    • (1996) J Biol Chem , vol.271 , pp. 6645-6650
    • Halvorson, L.M.1    Kaiser, U.B.2    Chin, W.W.3
  • 16
    • 15844387264 scopus 로고    scopus 로고
    • A steroidogenic factor-1 binding site is required for activity of the luteinizing hormone β subunit promoter in gonadotropes of transgenic mice
    • Keri RA, Nilson JH 1996 A steroidogenic factor-1 binding site is required for activity of the luteinizing hormone β subunit promoter in gonadotropes of transgenic mice. J Biol Chem 271:10782-10788
    • (1996) J Biol Chem , vol.271 , pp. 10782-10788
    • Keri, R.A.1    Nilson, J.H.2
  • 17
    • 0031021078 scopus 로고    scopus 로고
    • A binding site for steroidogenic factor-1 is part of a complex enhancer that mediates expression of the murine GnRH receptor gene
    • Duval DL, Nelson SE, Clay CM 1997 A binding site for steroidogenic factor-1 is part of a complex enhancer that mediates expression of the murine GnRH receptor gene. Biol Reprod 56:160-168
    • (1997) Biol Reprod , vol.56 , pp. 160-168
    • Duval, D.L.1    Nelson, S.E.2    Clay, C.M.3
  • 19
    • 0028276035 scopus 로고
    • Developmental expression of mouse steroidogenic factor-1, and essential regulator of the steroid hydroxylases
    • Ikeda Y, Shen W, Ingraham HA, Parker KL 1994 Developmental expression of mouse steroidogenic factor-1, and essential regulator of the steroid hydroxylases. Mol Endocrinol 8:654-662
    • (1994) Mol Endocrinol , vol.8 , pp. 654-662
    • Ikeda, Y.1    Shen, W.2    Ingraham, H.A.3    Parker, K.L.4
  • 20
    • 0027295482 scopus 로고
    • Characterization of the mouse FTZ-F1 gene, which encodes a key regulator of steroid hydroxylase gene expression
    • Ikeda Y, Lala DS, Luo X, Kim E, Moisan M-P, Parker KL 1993 Characterization of the mouse FTZ-F1 gene, which encodes a key regulator of steroid hydroxylase gene expression. Mol Endocrinol 7:852-860
    • (1993) Mol Endocrinol , vol.7 , pp. 852-860
    • Ikeda, Y.1    Lala, D.S.2    Luo, X.3    Kim, E.4    Moisan, M.-P.5    Parker, K.L.6
  • 21
    • 0029150668 scopus 로고
    • Cell-specific expression of the mouse gonadotropin-releasing hormone (GnRH) receptor gene is conferred by elements residing within 500 bp of proximal 5′ flanking region
    • Clay CM, Nelson SE, DiGregorio GB, Campion CE, Wiedemann AL, Nett RJ 1995 Cell-specific expression of the mouse gonadotropin-releasing hormone (GnRH) receptor gene is conferred by elements residing within 500 bp of proximal 5′ flanking region. Endocrine 3:615-622
    • (1995) Endocrine , vol.3 , pp. 615-622
    • Clay, C.M.1    Nelson, S.E.2    DiGregorio, G.B.3    Campion, C.E.4    Wiedemann, A.L.5    Nett, R.J.6
  • 22
    • 0028036664 scopus 로고
    • Isolation and characterization of the 5′-flanking region of the mouse gonadotropin-releasing hormone receptor gene
    • Albarracin CT, Kaiser UB, Chin WW 1994 Isolation and characterization of the 5′-flanking region of the mouse gonadotropin-releasing hormone receptor gene. Endocrinology 135:2300-2306
    • (1994) Endocrinology , vol.135 , pp. 2300-2306
    • Albarracin, C.T.1    Kaiser, U.B.2    Chin, W.W.3
  • 23
    • 0019792440 scopus 로고
    • Human placental receptors for luteinizing hormone releasing hormone
    • Currie AJ, Fraser HM, Sharpe RM 1981 Human placental receptors for luteinizing hormone releasing hormone. Biochem Biophys Res Commun 99:332-338
    • (1981) Biochem Biophys Res Commun , vol.99 , pp. 332-338
    • Currie, A.J.1    Fraser, H.M.2    Sharpe, R.M.3
  • 24
    • 0028799871 scopus 로고
    • Expression of gonadotropin-releasing hormone and gonadotropin releasing hormone receptor mRNAs in various non-reproductive human tissues
    • Kakar SS, Jennes L 1995 Expression of gonadotropin-releasing hormone and gonadotropin releasing hormone receptor mRNAs in various non-reproductive human tissues. Cancer Lett 98:57-62
    • (1995) Cancer Lett , vol.98 , pp. 57-62
    • Kakar, S.S.1    Jennes, L.2
  • 25
    • 0024517094 scopus 로고
    • Enhancer and promoter element interactions dictate cyclic adenosine monophosphate mediated and cell-specific expression of the glycoprotein hormone α-gene
    • Jameson JL, Powers AC, Gallagher GD, Habener JF 1989 Enhancer and promoter element interactions dictate cyclic adenosine monophosphate mediated and cell-specific expression of the glycoprotein hormone α-gene. Mol Endocrinol 3:763-772
    • (1989) Mol Endocrinol , vol.3 , pp. 763-772
    • Jameson, J.L.1    Powers, A.C.2    Gallagher, G.D.3    Habener, J.F.4
  • 26
    • 0024343938 scopus 로고
    • Expression of the glycoprotein hormone alpha-subunit gene in the placenta requires a functional cyclic AMP response element, whereas a different cis-acting element mediates pituitary-specific expression
    • Bokar JA, Keri RA, Farmerie TA, Fenstermaker RA, Andersen B, Hamernik DL, Yun J, Wagner T, Nilson JH 1989 Expression of the glycoprotein hormone alpha-subunit gene in the placenta requires a functional cyclic AMP response element, whereas a different cis-acting element mediates pituitary-specific expression. Mol Cell Biol 9:5113-5122
    • (1989) Mol Cell Biol , vol.9 , pp. 5113-5122
    • Bokar, J.A.1    Keri, R.A.2    Farmerie, T.A.3    Fenstermaker, R.A.4    Andersen, B.5    Hamernik, D.L.6    Yun, J.7    Wagner, T.8    Nilson, J.H.9
  • 27
    • 0028806064 scopus 로고
    • The human growth hormone gene is regulated by a multi-component locus control region
    • Jones BK, Monks BR, Liebhaber SA, Cooke NE 1995 The human growth hormone gene is regulated by a multi-component locus control region. Mol Cell Biol 15:7010-7021
    • (1995) Mol Cell Biol , vol.15 , pp. 7010-7021
    • Jones, B.K.1    Monks, B.R.2    Liebhaber, S.A.3    Cooke, N.E.4
  • 28
    • 0029035303 scopus 로고
    • Cooperation between elements of an organ-specific transcriptional enhancer in animals
    • Kruse F, Rose SD, Swift GH, Hammer RE, MacDonald RJ 1995 Cooperation between elements of an organ-specific transcriptional enhancer in animals. Mol Cell Biol 15:4385-4394
    • (1995) Mol Cell Biol , vol.15 , pp. 4385-4394
    • Kruse, F.1    Rose, S.D.2    Swift, G.H.3    Hammer, R.E.4    MacDonald, R.J.5
  • 29
    • 0028357757 scopus 로고
    • Integration of multiple signals through a complex hormone response unit in the phosphoenolpyruvate carboxykinase gene promoter
    • Mitchell J, Noisin E, Hall R, O'Brien R, Imai E, Granner D 1994 Integration of multiple signals through a complex hormone response unit in the phosphoenolpyruvate carboxykinase gene promoter. Mol Endocrinol 8:585-594
    • (1994) Mol Endocrinol , vol.8 , pp. 585-594
    • Mitchell, J.1    Noisin, E.2    Hall, R.3    O'Brien, R.4    Imai, E.5    Granner, D.6
  • 30
    • 0023268913 scopus 로고
    • Cyclic AMP regulation of the human glycoprotein hormone alpha-subunit gene is mediated by an 18-base-pair element
    • Silver BJ, Bokar JA, Virgin JB, Vallen ER, Milsted A, Nilson JA 1987 Cyclic AMP regulation of the human glycoprotein hormone alpha-subunit gene is mediated by an 18-base-pair element. Proc Natl Acad Sci USA 84:2198-2202
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 2198-2202
    • Silver, B.J.1    Bokar, J.A.2    Virgin, J.B.3    Vallen, E.R.4    Milsted, A.5    Nilson, J.A.6
  • 31
    • 0029006385 scopus 로고
    • Cooperative interaction of GATA-2 and AP1 regulates transcription of the endothelin-1 gene
    • Kawana M, Lee M, Quertermous EE 1995 Cooperative interaction of GATA-2 and AP1 regulates transcription of the endothelin-1 gene. Mol Cell Biol 15:4225-4231
    • (1995) Mol Cell Biol , vol.15 , pp. 4225-4231
    • Kawana, M.1    Lee, M.2    Quertermous, E.E.3
  • 32
    • 0026606084 scopus 로고
    • Fos and Jun repress transcriptional activation by myogenin and MyoD: The amino terminus of Jun can mediate repression
    • Li L, Chambard JC, Karin M, Olson EN 1992 Fos and Jun repress transcriptional activation by myogenin and MyoD: the amino terminus of Jun can mediate repression. Genes Dev 6:676-689
    • (1992) Genes Dev , vol.6 , pp. 676-689
    • Li, L.1    Chambard, J.C.2    Karin, M.3    Olson, E.N.4
  • 33
    • 0025986117 scopus 로고
    • Novel pathway for thyroid hormone receptor action through interaction with jun and fos oncogene activities
    • Zhang X, Wills KN, Husmann M, Hermann T, Pfahl M 1991 Novel pathway for thyroid hormone receptor action through interaction with jun and fos oncogene activities. Mol Cell Biol 11:6016-6025
    • (1991) Mol Cell Biol , vol.11 , pp. 6016-6025
    • Zhang, X.1    Wills, K.N.2    Husmann, M.3    Hermann, T.4    Pfahl, M.5
  • 34
    • 0028143056 scopus 로고
    • Interplay between estrogens, progestins, retinoid acid and AP-1 on a single regulatory site in the progesterone receptor gene
    • Savouret J, Rauch M, Redeuilh G, Sar S, Chauchereau A, Woodruff K, Parker MG, Milgrom E 1994 Interplay between estrogens, progestins, retinoid acid and AP-1 on a single regulatory site in the progesterone receptor gene. J Biol Chem 269:28955-28962
    • (1994) J Biol Chem , vol.269 , pp. 28955-28962
    • Savouret, J.1    Rauch, M.2    Redeuilh, G.3    Sar, S.4    Chauchereau, A.5    Woodruff, K.6    Parker, M.G.7    Milgrom, E.8
  • 35
    • 0029761277 scopus 로고    scopus 로고
    • A new group of conserved coactivators that increase the specificity of AP-1 transcription factors
    • Claret F-X, Hibi M, Dhut S, Toda T, Karin M 1996 A new group of conserved coactivators that increase the specificity of AP-1 transcription factors. Nature 383:453-457
    • (1996) Nature , vol.383 , pp. 453-457
    • Claret, F.-X.1    Hibi, M.2    Dhut, S.3    Toda, T.4    Karin, M.5
  • 36
    • 0029151923 scopus 로고    scopus 로고
    • A composite Ets/Pit-1 binding site in the prolactin gene can mediate transcriptional responses to multiple signal transduction pathways
    • Howard PW, Maurer RA 1997 A composite Ets/Pit-1 binding site in the prolactin gene can mediate transcriptional responses to multiple signal transduction pathways. J Biol Chem 270:20930-20936
    • (1997) J Biol Chem , vol.270 , pp. 20930-20936
    • Howard, P.W.1    Maurer, R.A.2
  • 37
    • 8544262895 scopus 로고    scopus 로고
    • Expression of a murine gonadotropin-releasing hormone receptor-luciferase fusion gene in transgenic mice is diminished by immunoneutralization of gonadotropin-releasing hormone
    • McCue JM, Quirk CC, Nelson SE, Bowen RA, Clay CM 1997 Expression of a murine gonadotropin-releasing hormone receptor-luciferase fusion gene in transgenic mice is diminished by immunoneutralization of gonadotropin-releasing hormone. Endocrinology 138: 3154-3160
    • (1997) Endocrinology , vol.138 , pp. 3154-3160
    • McCue, J.M.1    Quirk, C.C.2    Nelson, S.E.3    Bowen, R.A.4    Clay, C.M.5
  • 38
    • 0003450711 scopus 로고
    • SAS Institute Inc., Cary, NC
    • SAS/STAT 1989 User's Guide. Version 6, ed. 4. SAS Institute Inc., Cary, NC, vol 1
    • (1989) User's Guide. Version 6, Ed. 4. , vol.1


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