Role of Aspartate 7.32(302) of the human gonadotropin-releasing hormone receptor in stabilizing a high-affinity ligand conformation

Molecular Pharmacology

Volumn 60, Issue 6, 2001, Pages 1280-1287

  Fromme, B J ^a   Katz, A A ^a   Roeske, R W ^a   Millar, R P ^a   Flanagan, C A ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; ASPARTIC ACID; GLUTAMIC ACID; GONADORELIN DERIVATIVE; GONADORELIN RECEPTOR; GONADORELIN; LACTAM; LIGAND;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONFORMATION; CONFORMATIONAL TRANSITION; DRUG RECEPTOR BINDING; NONHUMAN; PRIORITY JOURNAL; RECEPTOR INTRINSIC ACTIVITY; RECEPTOR OCCUPANCY; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; ANIMAL; BINDING COMPETITION; CELL STRAIN COS1; CHEMISTRY; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; MUTATION; PROTEIN CONFORMATION; RADIOASSAY;

AMINO ACID SUBSTITUTION; ANIMAL; ARGININE; ASPARTIC ACID; BINDING, COMPETITIVE; COS CELLS; GONADORELIN; HUMAN; LACTAMS; LIGANDS; MUTATION; PROTEIN CONFORMATION; RADIOLIGAND ASSAY; TRANSFECTION;

EID: 0034747357     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.60.6.1280     Document Type: Article

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