Multiple interactions of the Asp(2.61(98)) side chain of the gonadotropin-releasing hormone receptor contribute differentially to ligand interaction

Biochemistry

Volumn 39, Issue 28, 2000, Pages 8133-8141

  Flanagan, Colleen A ^a,b   Rodic, Vladimir ^a   Konvicka, Karel ^a   Yuen, Tony ^a   Chi, Ling ^a   Rivier, Jean E ^c   Millar, Robert P ^b,d   Weinstein, Harel ^a   Sealfon, Stuart C ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

^c SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^d MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; GONADORELIN; GONADORELIN RECEPTOR;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; BINDING SITE; COMPLEX FORMATION; GENE EXPRESSION; HYDROGEN BOND; LIGAND BINDING; MUTATION; PRIORITY JOURNAL; PROTEIN INTERACTION;

ANIMALS; ASPARTIC ACID; BINDING, COMPETITIVE; COMPUTER SIMULATION; COS CELLS; GENE EXPRESSION; GONADOTROPIN-RELEASING HORMONE; INOSITOL PHOSPHATES; LIGANDS; MODELS, MOLECULAR; MUTATION; OSMOLAR CONCENTRATION; PEPTIDES; RECEPTORS, LHRH;

EID: 0034682639     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi000085g     Document Type: Article

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