Gonadotropin-releasing hormone messenger RNA expression in gonadotroph tumors and normal human pituitary

Journal of Clinical Endocrinology and Metabolism

Volumn 81, Issue 1, 1996, Pages 80-83

  Miller, Gregory M ^a   Alexander, Joseph M ^a   Klibanski, Anne ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FOLLITROPIN; GONADORELIN; GONADORELIN RECEPTOR; LUTEINIZING HORMONE; MESSENGER RNA;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; HYPOPHYSIS ADENOMA; MALE; PRIORITY JOURNAL; RADIOIMMUNOASSAY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION;

ADENOMA; ADULT; AGED; BASE SEQUENCE; FEMALE; GONADOTROPIN-RELEASING HORMONE; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PITUITARY GLAND; PITUITARY NEOPLASMS; POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 0030029162     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.81.1.80     Document Type: Article

References (34)

1. Black PM, Hsu DW, Klibanski A, et al. 1987 Hormone production in clinically nonfunctioning pituitary adenomas. J Neurosurg. 66:244-250.
2. Jameson JL, Klibanski A, Black PM, et al. 1987 Glycoprotein hormone genes are expressed in clinically nonfunctioning pituitary adenomas. J Clin Invest. 80:1472-1478.
3. Vaitukaitis JL. 1974 Changing placontal concentrations of human chorionic gonadotropin and its subunits during gestation. J Clin Endocrinol Metab. 38:755-760.
4. Kourides IA, Landon MB, Hoffman BJ, Weintraub BD. 1980 Excess free alpha relative to beta subunits of the glycoprotein hormones in normal and abnormal human pituitary glands. Clin Endocrinol (Oxf). 12:407-416.
5. Jameson JL, Lindell CM, Habener JF. 1987 Gonadotropin and thyrotropin alpha- and beta-subunit gene expression in normal and neoplastic tissues characterized using specific messenger ribonucleic acid hybridization probes. J Clin Endocrinol Metab. 64:319-327.
6. Katznelson L, Alexander JM, Bikkal HA, Jameson JL, Hsu DW, Klibanski A. 1992 Imbalanced follicle-stimulating hormone beta-subunit hormone biosynthesis in human pituitary adenomas. J Clin Endocrinol Metab. 74:1343-1351.
7. Klibanski A, Deutsch FJ, Jameson JL, et al. 1987 Luteinizing hormone-secreting pituitary tumor: biosynthetic characterization and clinical studies. J Clin Endocrinol Metab. 64:536-542.
8. Klibanski A, Jameson JL, Biller BMK, et al. 1989 Gonadotropin and alpha-subunit responses to chronic gonadotropin-releasing hormone analog administration in patients with glycoprotein hormone-secreting pituitary tumors. J Clin Endocrinol Metab. 68:81-86.
9. Culler MD, Negro-Vilar A. 1986 Evidence that pulsatile follicle-stimulating hormone secretion is independent of endogenous luteinizing hormone-releasing hormone. Endocrinology. 118:609-612.
10. May V, Wilber JF, U'Prichard DC, Childs GV. 1987 Persistence of immunoreactive TRH and GnRH in long-term primary anterior pituitary cultures. Peptides. 8:543-558.
11. Pagesy P, Li JY, Berthet M, Peillon F. 1992 Evidence of gonadotropin-releasing hormone mRNA in the rat anterior pituitary. Mol Endocrinol. 6:523-528.
12. Kerdelhue B, Lenoir V, Toner J, et al. 1990 The GnRH precursor is present in the anterior pituitary gland, and an important increase in its content precedes serum LH surge induced by estradiol-17 beta in female primates. [French]. C R Acad Sci Ill. 311:479-485.
13. Chomczynski P, Sacchi N. 1987 Single-step method of RNA isolation by acid guanidinium thiocyariate-phenol-chloroform extraction. Anal Biochem. 162: 156-159.
14. Dong KW, Yu KL, Roberts JL. 1993 Identification of a major up-stream transcription start site for the human progonadotropin-releasing hormone gene used in reproductive tissues and cell lines. Mol Endocrinol. 7:1654-1666.
15. Klibanski A, Shupnik MA, Bikkal HA, Black PM, Kliman B, Zervas NT, 1988 Dopaminergic regulation of alpha-subunit secretion and messenger ribonucleic acid levels in alpha-secreting pituitary tumors. J Clin Endocrinol Metab. 66:96-102.
16. Nett TM, Akbar AM, Niswender GD, Hedlund MT, White WF. 1973 A radioimmunoassay for gonadotropin-releasing hormone (Gn-RH) in serum. J Clin Endocrinol Metab. 36:880-885.
17. Odell WD, Ross GT, Rayford PL. 1967 Radioimmunoassay for luteinizing hormone in human plasma or serum. J Clin Invest. 46:248-255.
18. Snyder PJ, Johnson J, Muzyka R. 1980 Abnormal secretion of glycoprotein alpha-subunit and follicle-stimulating hormone (FSH) beta-subunit in men with pituitary adenomas and FSH hypersecretion. J Clin Endocrinol Metab. 51:579-584.
19. Snyder PJ, Bashey HM, Kim SU, Chappel SC. 1984 Secretion of uncombined subunits of luteinizing hormone by gonadotroph cell adenomas. J Clin Endocrinol Metab. 59:1169-1175.
20. Thotakura NR, Bahl OP. 1985 Highly specific and sensitive hybridoma antibodies against the alpha subunit of human glycoprotein hormones. Endocrinology. 117:1300-1308.
21. Kourides IA, Weintraub BD, Levko MA, Maloof F. 1974 Alpha and beta subunits of human thyrotropin: purification and development of specific radioimmunoassay. Endocrinology. 94:1411-1421.
22. Hsu DW, Riskind PN, Hedley-Whyte E. 1989 Vasoactive intestinal peptide in the human pituitary gland and adenomas. An immunocytochemical study. Am J Pathol. 135:329-338.
23. Shupnik MA. 1990 Effects of gonadotropin-releasing hormone on rat gonadotropin gene transcription in vitro: requirement for pulsatile administration for luteinizing hormone-beta gene stimulation. Mol Endocrinol. 4:1444-1450.
24. Haisenleder DJ, Dalkin AC, Ortolano GA, Marshall JC, Shupnik MA. 1991 A pulsatile gonadotropin-releasing hormone stimulus is required to increase transcription of the gonadotropin subunit genes: evidence for differential regulation of transcription by pulse frequency in vivo. Endocrinology. 128:509-517,
25. Strobl FJ, Levine JE. 1988 Estrogen inhibits luteinizing hormone (LH), but not follicle-stimulating hormone secretion in hypophysectomized pituitary-grafted rats receiving pulsatile LH-releasing hormone infusions. Endocrinology. 123:622-630.
26. Samuels MH, Henry P, Kleinschmidt-Demasters BK, Lillehei K, Ridgway EC. 1991 Pulsatile glycoprotein hormone secretion in glycoprotein-producing pituitary tumors. J Clin Endocrinol Metab. 73:1281-1288.
27. Lamberts SW, Verleun T, Oosterom R, et al. 1987 Effects of bromocriptine, thyrotropin-releasing hormone, and gonadotropin-releasing hormone on hormone secretion by gonadotropin-secreting pituitary adenomas in vivo and in vitro. J Clin Endocrinol Metab. 64:524-530.
28. Kwekkeboom DJ, de Jong FH, Lamberts SW. 1989 Gonadotropin release by clinically nonfunctioning and gonadotroph pituitary adenomas in vivo and in vitro: relation to sex and effects of thyrotropin-releasing hormone, gonadotropin-releasing hormone, and bromocryptine. J Clin Endocrinol Metab. 68: 1128-1135.
29. Spada A, Reza-Elahi F, Lania A, Gil-del-Alamo P, Bassetti M, Faglia G. 1991 Hypothalamic peptides modulate cytosolic free Ca2+ levels and adenylyl cyclase activity in human nonfunctioning pituitary adenomas. J Clin Endocrinol Metab. 73:913-918.
30. Alexander JM, Klibanski A. 1994 Gonadotropin-releasing hormone receptor mRNA expression by human pituitary tumors in vitro. J Clin Invest. 93:2332-2339.
31. Peng C, Fan NC, Ligier M, Vaananen J, Leung PC. 1994 Expression and regulation of gonadotropin-releasing hormone (GnRH) and GnRH receptor messenger ribonudeic acids in human granulosa-luteal Cells. Endocrinology. 135:1740-1746.
32. Olofsson JI, Conti CC, Leung PC. 1995 Homologous and heterologous regulation of gonadotropin-releasing hormone receptor gene expression in preovulatory rat granulosa cells. Endocrinology. 136:974-980.
33. Kaiser UB, Jakubowiak A, Steinberger A, Chin WW. 1993 Regulation of rat pituitary gonadotropin-releasing hormone receptor mRNA levels in vivo and in vitro. Endocrinology. 133:931-934.
34. Dong KW, Roberts JL. Translation of the human reproductive specific GnRH mRNA. 24th Annual Meeting of the Society of Neuroscience. 1994, Miami FL; (Abstract) 43:8.