Differential use of signal transduction pathways in the gonadotropin- releasing hormone-mediated regulation of gonadotropin subunit gene expression

Endocrinology

Volumn 139, Issue 4, 1998, Pages 1835-1843

  Saunders, Brian D ^a   Sabbagh, Elena ^a   Chin, William W ^a   Kaiser, Ursula B ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; GONADORELIN; GONADORELIN RECEPTOR; GONADOTROPIN; GUANINE NUCLEOTIDE BINDING PROTEIN; NIMODIPINE; PHORBOL 12 ACETATE 13 MYRISTATE;

ARTICLE; CALCIUM CELL LEVEL; HORMONAL REGULATION; PRIORITY JOURNAL; REGULATORY MECHANISM; REPORTER GENE; SIGNAL TRANSDUCTION;

EID: 0031762011     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.139.4.5972     Document Type: Article

References (37)

1. Gharib SD, Wierman ME, Shupnik MA, Chin WW 1990 Molecular biology of the pituitary gonadotropins. Endocr Rev 11:177-199
2. Belchetz PE, Plant TM, Nakai Y, Keogh EJ, Knobil E 1978 Hypophysial responses to continuous and intermittent delivery of hypothalamic gonadotropin-releasing hormone. Science 202:631-633
3. Wildt L, Hausler A, Marshall G, Hutchison JS, Plant TM, Belchetz PE, Knobil E 1981 Frequency and amplitude of gonadotropin-releasing hormone stimulation and gonadotropin secretion in the rhesus monkey. Endocrinology 109:376-385
4. Wierman ME, Rivier JE, Wang C 1989 GnRH-dependent regulation of gonadotropin subunit mRNA levels in the rat. Endocrinology 124:272-278
5. Dalkin AC, Haisenleder DJ, Ortolano GA, Ellis TR, Marshall JC 1989 The frequency of gonadotropin-releasing hormone stimulation differentially regulates gonadotropin subunit messenger ribonucleic acid expression. Endocrinology 125:917-924
6. Shupnik MA 1990 Effects of gonadotropin-releasing hormone on rat gonadotropin gene transcription in vitro: requirement for pulsatile administration for luteinizing hormone-β gene stimulation. Mol Endocrinol 4:1444-1450
7. Haisenleder DJ, Dalkin AC, Ortolano GA, Marshall JC, Shupnik MA 1991 A pulsatile gonadotropin-releasing hormone stimulus is required to increase transcription of the gonadotropin subunit genes: evidence for differential regulation of transcription by pulse frequency in vivo. Endocrinology 128:509-517
8. 11. Mol Endocrinol 6:1673-1681
9. Huckle WR, Conn PM 1987 The relationship between gonadotropin-releasing hormone-stimulated luteinizing hormone release and inositol phosphate production: studies with calcium antagonists and protein kinase C activators. Endocrinology 120:160-169
10. 2+ pools and relationship to gonadotropin secretion. Mol Endocrinol 2:512-520
11. Stojilkovic SS, Chang JP, Ngo D, Catt KJ 1988 Evidence for a role of protein kinase C in luteinizing hormone synthesis and secretion. J Biol Chem 263:17307-17311
12. Starzec A, Jutisz M, Counis R 1989 Cyclic adenosine monophosphate and phorbol ester, like gonadotropin-releasing hormone, stimulate the biosynthesis of luteinizing hormone polypeptide chains in a nonadditive manner. Mol Endocrinol 3:618-624
13. Hawes BE, Barnes SJ, Conn PM 1993 Cholera toxin and pertussis toxin provoke differential effects on luteinizing hormone release, inositol phosphate production, and gonadotropin-releasing hormone (GnRH) receptor binding in the gonadotrope: evidence for multiple guanyl nucleotide binding proteins in GnRH action. Endocrinology 132:2124-2130
14. Ishizaka K, Tsujii T, Winters SJ 1993 Evidence for a role for the cyclic adenosine 3', 5'-monophosphate/protein kinase-A pathway in regulation of the gonadotropin subunit messenger ribonucleic acids. Endocrinology 133:2040-2048
15. Borgeat P, Chavancy G, Dupont A, Labrie F, Arimura A, Schally AV 1972 Stimulation of adenosine 3' ,5'-cyclic monophosphate accumulation in anterior pituitary gland in vitro by synthetic luteinizing hormone-releasing hormone. Proc Natl Acad Sci USA 69:2677-2681
16. Sim PJ, Wolbers WB, Mitchell R 1995 Activation of MAP kinase by the LHRH receptor through a dual mechanism involving protein kinase C and a pertussis toxin-sensitive G protein. Mol Cell Endocrinol 112:257-263
17. Roberson MS, Misra-Press A, Laurance ME, Stork PJS, Maurer RA 1995 A role for mitogen-activated protein kinase in mediating activation of the glycoprotein hormone α-subunit promoter by gonadotropin-releasing hormone. Mol Cell Biol 15:3531-3539
18. Sundaresan S, Colin IM, Pestell RG, Jameson JL 1996 Stimulation of mitogenactivated protein kinase by gonadotropin-releasing hormone: evidence for the involvement of protein kinase C. Endocrinology 137:304-311
19. Conn PM 1989 Does protein kinase C mediate pituitary actions of gonadotropin-releasing hormone? Mol Endocrinol 3:755-757
20. Chang JP, Stojilkovic SS, Graeter JS, Catt KJ 1988 Gonadotropin-releasing hormone stimulates luteinizing hormone secretion by extracellular calciumdependent and -independent mechanisms. Endocrinology 122:87-97
21. Andrews WV, Maurer RA, Conn PM 1988 Stimulation of rat luteinizing hormone-β messenger RNA levels by gonadotropin releasing hormone: apparent role for protein kinase C. J Biol Chem 263:13755-13761
22. Ben-Menahem D, Naor Z 1994 Regulation of gonadotropin mRNA levels in cultured rat pituitary cells by gonadotropin-releasing hormone (GnRH): role for calcium and protein kinase C. Biochemistry 33:3698-3704
23. Holdstock JG, Aylwin SJB, Burrin JM 1996 Calcium and glycoprotein hormone α-subunit gene expression and secretion in αT3-1 gonadotropes. Mol Endocrinol 10:1308-1317
24. Ibrahim SN, Moussa SM, Childs GV 1986 Morphometric studies of rat anterior pituitary cells after gonadectomy: correlation of changes in gonadotropes with the serum levels of gonadotropins. Endocrinology 119:629-637
25. Tashjian Jr AH, Yasumura Y, Levine L, Sato GH, Parker ML 1968 Establishment of clonal strains of rat pituitary tumor cells that secrete growth hormone. Endocrinology 82:342-352
26. Hinkle PM, Tashjian Jr AH1973 Receptors for thyrotropin-releasing hormone in prolactin-producing rat pituitary cells in culture. J Biol Chem 248:6180-6186
27. Stanislaus D, Janovick JA, Jennes L, Kaiser UB, Chin WW, Conn PM 1994 Functional and morphological characterization of four cell lines derived from GH3 cells stably transfected with gonadotropin-releasing hormone receptor complementary deoxyribonucleic acid. Endocrinology 135:2220-2227
28. Kaiser UB, Katzenellenbogen RA, Conn PM, Chin WW 1994 Evidence that signalling pathways by which thyrotropin-releasing hormone and gonadotropin-releasing hormone act are both common and distinct. Mol Endocrinol 8:1038-1048
29. Kaiser UB, Sabbagh E, Katzenellenbogen RA, Conn PM, Chin WW 1995 A mechanism for the differential regulation of gonadotropin subunit gene expression by gonadotropin-releasing hormone. Proc Natl Acad Sci USA 92:12280-12284
30. Nordeen S 1988 Luciferase reporter gene vectors for analysis of promoters and enhancers. Biotechniques 6:454-458
31. Berridge MJ 1993 Inositol triphosphate and calcium signalling. Nature 361:315-325
32. Schoderbek WE, Roberson MS, Maurer RA 1993 Two different DNA elements mediate gonadotropin releasing hormone effects on expression of the glycoprotein hormone α-subunit gene. J Biol Chem 268:3903-3910
33. 2+ mobilizing hormones: the case of gonadotropin-reieasing hormone. Endocr Rev 11:326-353
34. Newton AC 1995 Protein kinase C: structure, function, and regulation. J Biol Chem 270:28495-28498
35. Yuan Q, Swerdloff R, Bhasin S 1988 Differential regulation of rat luteinizing hormone alpha- and beta-subunits during the stimulatory and down-regulatory phases of gonadotropin-releasing hormone action. Endocrinology 122:504-510
36. Weiss J, Jameson JL, Burrin JM, Crowley Jr WF 1990 Divergent responses of gonadotropin subunit messenger RNAs to continuous vs. pulsatile gonadotropin-releasing hormone in vitro. Mol Endocrinol 4:557-564
37. Landy H, Boepple PA, Mansfield MJ, Whitcomb RW, Schneyer AL, Crawford JD, Crigler Jr JF, Crowley Jr WF 1991 Altered patterns of pituitary secretion and renal excretion of free alpha-subunit during gonadotropin-releasing hormone agonist-induced pituitary desensitization. J Clin Endocrinol Metab 72:711-717