메뉴 건너뛰기




Volumn 34, Issue 4, 2004, Pages 433-444

The murine model of infection with Leishmania major and its importance for the deciphering of mechanisms underlying differences in Th cell differentiation in mice from different genetic backgrounds

Author keywords

Cytokines; Infection with Leishmania; Th1 Th2 responses

Indexed keywords

CYTOKINE;

EID: 1542298831     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpara.2003.11.021     Document Type: Review
Times cited : (77)

References (123)
  • 1
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas A.K., Murphy K.M., Sher A. Functional diversity of helper T lymphocytes. Nature. 383:1996;787-793.
    • (1996) Nature , vol.383 , pp. 787-793
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 6
    • 0034279242 scopus 로고    scopus 로고
    • A critical role for interleukin 4 in activating alloreactive CD4 T cells
    • Bagley J., Sawada T., Wu Y., Iacomini J. A critical role for interleukin 4 in activating alloreactive CD4 T cells. Nat. Immunol. 1:2000;257-261.
    • (2000) Nat. Immunol. , vol.1 , pp. 257-261
    • Bagley, J.1    Sawada, T.2    Wu, Y.3    Iacomini, J.4
  • 8
    • 0030612781 scopus 로고    scopus 로고
    • Serial backcross mapping of multiple loci associated with resistance to Leishmania major in mice
    • Beebe A., Mauze S., Schork N.J., Coffman R.L. Serial backcross mapping of multiple loci associated with resistance to Leishmania major in mice. Immunity. 6:1997;551-557.
    • (1997) Immunity , vol.6 , pp. 551-557
    • Beebe, A.1    Mauze, S.2    Schork, N.J.3    Coffman, R.L.4
  • 9
    • 0018648646 scopus 로고
    • Leishmania tropica: Pathogenicity and in vitro macrophage function of inbred mice
    • Behin R., Maüel J., Sordat B. Leishmania tropica: pathogenicity and in vitro macrophage function of inbred mice. Exp. Parasitol. 48:1979;81-91.
    • (1979) Exp. Parasitol. , vol.48 , pp. 81-91
    • Behin, R.1    Maüel, J.2    Sordat, B.3
  • 10
    • 0035914841 scopus 로고    scopus 로고
    • The role of interleukin(IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptor antibody for sterile cure
    • Belkaid Y., Hoffmann K.F., Mendez S., Kamhawi S., Udey M.C., Wynn T.A., Sacks D.L. The role of interleukin(IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptor antibody for sterile cure. J. Exp. Med. 194:2001;1497-1506.
    • (2001) J. Exp. Med. , vol.194 , pp. 1497-1506
    • Belkaid, Y.1    Hoffmann, K.F.2    Mendez, S.3    Kamhawi, S.4    Udey, M.C.5    Wynn, T.A.6    Sacks, D.L.7
  • 12
    • 0024412797 scopus 로고
    • Administration of monoclonal anti-IFN-γ antibodies in vivo abrogates natural resistance of C3H/HeN mice to infection with Leishmania major
    • Belosevic M., Finbloom D.S., van der Meide P.H., Slayter M.V., Nacy C.A. Administration of monoclonal anti-IFN-γ antibodies in vivo abrogates natural resistance of C3H/HeN mice to infection with Leishmania major. J. Immunol. 143:1989;266-274.
    • (1989) J. Immunol. , vol.143 , pp. 266-274
    • Belosevic, M.1    Finbloom, D.S.2    Van Der Meide, P.H.3    Slayter, M.V.4    Nacy, C.A.5
  • 16
    • 0032898950 scopus 로고    scopus 로고
    • Experimental Leishmania major infection in mice: Role of IL-10
    • Chatelain R., Mauze S., Coffman R. Experimental Leishmania major infection in mice: role of IL-10. Parasite Immunol. 21:1999;211-218.
    • (1999) Parasite Immunol. , vol.21 , pp. 211-218
    • Chatelain, R.1    Mauze, S.2    Coffman, R.3
  • 17
  • 18
    • 0023622458 scopus 로고
    • Two types of mouse helper T cell clones. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies
    • Cherwinski H.M., Schumacher J.H., Brown K.D., Mosmann T.R. Two types of mouse helper T cell clones. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies. J. Exp. Med. 166:1987;1229-1244.
    • (1987) J. Exp. Med. , vol.166 , pp. 1229-1244
    • Cherwinski, H.M.1    Schumacher, J.H.2    Brown, K.D.3    Mosmann, T.R.4
  • 19
    • 0032442862 scopus 로고    scopus 로고
    • Interleukin-4 and interleukin-13: Their similarities and discrepancies
    • Chomarat P., Banchereau J. Interleukin-4 and interleukin-13: their similarities and discrepancies. Int. Rev. Immunol. 17:1998;1-52.
    • (1998) Int. Rev. Immunol. , vol.17 , pp. 1-52
    • Chomarat, P.1    Banchereau, J.2
  • 20
    • 2642613665 scopus 로고    scopus 로고
    • The resolution of lesions induced by Leishmania major in mice requires a functional Fas (APO-1, CD95) pathway of cytotoxicyty
    • Conceiçao-Silva F., Hahne M., Schröter M., Louis J., Tschopp J. The resolution of lesions induced by Leishmania major in mice requires a functional Fas (APO-1, CD95) pathway of cytotoxicyty. Eur. J. Immunol. 28:1998;237-245.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 237-245
    • Conceiçao-Silva, F.1    Hahne, M.2    Schröter, M.3    Louis, J.4    Tschopp, J.5
  • 21
    • 0028089795 scopus 로고
    • Differential effects of blockade of CD28-B7 on the development of Th1 or Th2 effector cells in experimental leishmaniasis
    • Corry D.B., Reiner S.L., Linsley P.S., Locksley R.M. Differential effects of blockade of CD28-B7 on the development of Th1 or Th2 effector cells in experimental leishmaniasis. J. Immunol. 153:1994;4142-4148.
    • (1994) J. Immunol. , vol.153 , pp. 4142-4148
    • Corry, D.B.1    Reiner, S.L.2    Linsley, P.S.3    Locksley, R.M.4
  • 22
    • 0035170378 scopus 로고    scopus 로고
    • Production of IL-12 by human monocyte-derived dendritic cells is optimal when the stimulus is given at the onset of maturation, and its further enhanced by IL-4
    • Ebner S., Ratzinger G., Krosbacher B., Schmuth M., Weiss A., Reider D., Krockzek R.A., Herold M., Heufler C., Fritsch P., Romani N. Production of IL-12 by human monocyte-derived dendritic cells is optimal when the stimulus is given at the onset of maturation, and its further enhanced by IL-4. J. Immunol. 166:2001;633-641.
    • (2001) J. Immunol. , vol.166 , pp. 633-641
    • Ebner, S.1    Ratzinger, G.2    Krosbacher, B.3    Schmuth, M.4    Weiss, A.5    Reider, D.6    Krockzek, R.A.7    Herold, M.8    Heufler, C.9    Fritsch, P.10    Romani, N.11
  • 23
    • 0042991289 scopus 로고    scopus 로고
    • + T cell polarisation in mice is modulated by strain-specific major histocompatibility complex-independent differences within dendritic cells
    • + T cell polarisation in mice is modulated by strain-specific major histocompatibility complex-independent differences within dendritic cells. J. Exp. Med. 198:2003;201-209.
    • (2003) J. Exp. Med. , vol.198 , pp. 201-209
    • Filippi, C.1    Hugues, S.2    Cazareth, J.3    Julia, V.4    Glaichenhaus, N.5    Ugolini, S.6
  • 25
    • 0037013930 scopus 로고    scopus 로고
    • Mechanisms of transforming growth factor-β-induced inhibition of T helper type I differentiation
    • Gorelik L., Constant S.L., Flavell R.A. Mechanisms of transforming growth factor-β-induced inhibition of T helper type I differentiation. J. Exp. Med. 195:2002;1499-1505.
    • (2002) J. Exp. Med. , vol.195 , pp. 1499-1505
    • Gorelik, L.1    Constant, S.L.2    Flavell, R.A.3
  • 26
    • 0025648446 scopus 로고
    • Leishmania major amastigotes initiate the L-arginine dependent killing mechanism in IFN-γ-stimulated macrophages by induction of TNF-α
    • Green S.J., Crawford R.M., Hockmeyer J.T., Meltzer M.S., Nacy C.A. Leishmania major amastigotes initiate the L-arginine dependent killing mechanism in IFN-γ-stimulated macrophages by induction of TNF-α J. Immunol. 145:1990;4290-4297.
    • (1990) J. Immunol. , vol.145 , pp. 4290-4297
    • Green, S.J.1    Crawford, R.M.2    Hockmeyer, J.T.3    Meltzer, M.S.4    Nacy, C.A.5
  • 28
    • 0030062937 scopus 로고    scopus 로고
    • Selective development of T helper (Th)2 cells induced by continuous administration of low dose soluble proteins to normal and β2-microglobulin- deficient BALB/c mice
    • Guéry J.-C., Galbiati F., Smiroldo S., Adorini L. Selective development of T helper (Th)2 cells induced by continuous administration of low dose soluble proteins to normal and β2-microglobulin-deficient BALB/c mice. J. Exp. Med. 183:1996;485-497.
    • (1996) J. Exp. Med. , vol.183 , pp. 485-497
    • Guéry, J.-C.1    Galbiati, F.2    Smiroldo, S.3    Adorini, L.4
  • 30
    • 0024540908 scopus 로고
    • Reciprocal expression of interferon γ or interleukin 4 during the resolution or progression of murine leishmaniasis
    • Heinzel F.P., Sadick M.D., Holaday B.J., Coffman R.L., Locksley R.M. Reciprocal expression of interferon γ or interleukin 4 during the resolution or progression of murine leishmaniasis. J. Exp. Med. 169:1989;59-72.
    • (1989) J. Exp. Med. , vol.169 , pp. 59-72
    • Heinzel, F.P.1    Sadick, M.D.2    Holaday, B.J.3    Coffman, R.L.4    Locksley, R.M.5
  • 31
    • 0027158442 scopus 로고
    • IL-2 is necessary for the progression of leishmaniasis in susceptible murine hosts
    • Heinzel F.P., Rerko R.M., Hatam F., Locksley R.M. IL-2 is necessary for the progression of leishmaniasis in susceptible murine hosts. J. Immunol. 150:1993;3924-3931.
    • (1993) J. Immunol. , vol.150 , pp. 3924-3931
    • Heinzel, F.P.1    Rerko, R.M.2    Hatam, F.3    Locksley, R.M.4
  • 33
    • 0029076809 scopus 로고
    • Endogenous IL-12 is required for control of Th2 cytokine responses capable of exacerbating leishmaniasis in normally resistant mice
    • Heinzel F.P., Rerko R.M., Ahmed F., Pearlman E. Endogenous IL-12 is required for control of Th2 cytokine responses capable of exacerbating leishmaniasis in normally resistant mice. J. Immunol. 155:1995;730-739.
    • (1995) J. Immunol. , vol.155 , pp. 730-739
    • Heinzel, F.P.1    Rerko, R.M.2    Ahmed, F.3    Pearlman, E.4
  • 35
    • 0030068217 scopus 로고    scopus 로고
    • Cloning and characterization of a binding subunit of the interleukin-13 receptor that is also a component of the interleukin-4 receptor
    • Hilton D.J., Zhang J.-G., Metcalf D., Alexander W.S., Nicola N.A., Wilson T.A. Cloning and characterization of a binding subunit of the interleukin-13 receptor that is also a component of the interleukin-4 receptor. Proc. Natl. Acad. Sci. USA. 93:1996;497-501.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 497-501
    • Hilton, D.J.1    Zhang, J.-G.2    Metcalf, D.3    Alexander, W.S.4    Nicola, N.A.5    Wilson, T.A.6
  • 37
    • 0034193027 scopus 로고    scopus 로고
    • In BALB/c mice, IL-4 production during the initial phase of infection with Leishmania major is necessary and sufficient to instruct Th2 cell development resulting in progressive disease
    • Himmelrich H., Launois P., Maillard I., Biedermann T., Tacchini-Cottier F., Locksley R.M., Röcken M., Louis J.A. In BALB/c mice, IL-4 production during the initial phase of infection with Leishmania major is necessary and sufficient to instruct Th2 cell development resulting in progressive disease. J. Immunol. 164:2000;4819-4825.
    • (2000) J. Immunol. , vol.164 , pp. 4819-4825
    • Himmelrich, H.1    Launois, P.2    Maillard, I.3    Biedermann, T.4    Tacchini-Cottier, F.5    Locksley, R.M.6    Röcken, M.7    Louis, J.A.8
  • 38
    • 0033802387 scopus 로고    scopus 로고
    • Interleukin (IL)-4 is a major regulatory cytokine governing bioactive IL-12 production by mouse and human dendritic cells
    • Hochrein H., O'Keefe M., Luft T., Vandenabeele S., Grumont R.J., Maraskovsky E., Shortman K. Interleukin (IL)-4 is a major regulatory cytokine governing bioactive IL-12 production by mouse and human dendritic cells. J. Exp. Med. 192:2000;823-833.
    • (2000) J. Exp. Med. , vol.192 , pp. 823-833
    • Hochrein, H.1    O'Keefe, M.2    Luft, T.3    Vandenabeele, S.4    Grumont, R.J.5    Maraskovsky, E.6    Shortman, K.7
  • 40
    • 0032063360 scopus 로고    scopus 로고
    • Mice defective in Fas are highly susceptible to Leishmania major infection despite elevated IL-12 synthesis, strong Th1 responses and enhanced nitric oxide production
    • Huang F.P., Xu D., Esfandiari E.O., Sands W., Wei X.Q., Liew F.Y. Mice defective in Fas are highly susceptible to Leishmania major infection despite elevated IL-12 synthesis, strong Th1 responses and enhanced nitric oxide production. J. Immunol. 1998;4143-4147.
    • (1998) J. Immunol. , pp. 4143-4147
    • Huang, F.P.1    Xu, D.2    Esfandiari, E.O.3    Sands, W.4    Wei, X.Q.5    Liew, F.Y.6
  • 42
    • 0029849205 scopus 로고    scopus 로고
    • Resistance to Leishmania major induced by tolerance to a single antigen
    • Julia V., Rassoulzadegan M., Glaichenhaus N. Resistance to Leishmania major induced by tolerance to a single antigen. Science. 274:1996;421-423.
    • (1996) Science , vol.274 , pp. 421-423
    • Julia, V.1    Rassoulzadegan, M.2    Glaichenhaus, N.3
  • 44
    • 0029933509 scopus 로고    scopus 로고
    • Protective role of CD40 in Leishmania major infection at two distinct phases of cell-mediated immunity
    • Kamanaka M., Yu P., Yasui T., Yoshida K., Kawabe T., Horii T., Kishimoto T., Kikutani H. Protective role of CD40 in Leishmania major infection at two distinct phases of cell-mediated immunity. Immunity. 4:1996;275-281.
    • (1996) Immunity , vol.4 , pp. 275-281
    • Kamanaka, M.1    Yu, P.2    Yasui, T.3    Yoshida, K.4    Kawabe, T.5    Horii, T.6    Kishimoto, T.7    Kikutani, H.8
  • 45
    • 0027788043 scopus 로고
    • The relationship of IL-4- and IFN-γ-producing T cells studied by lineage ablation of IL-4 producing cells
    • Kamogawa Y., Minasi L.-A., Carding S.R., Bottomly K., Flavell R.A. The relationship of IL-4- and IFN-γ-producing T cells studied by lineage ablation of IL-4 producing cells. Cell. 75:1993;985-995.
    • (1993) Cell , vol.75 , pp. 985-995
    • Kamogawa, Y.1    Minasi, L.-A.2    Carding, S.R.3    Bottomly, K.4    Flavell, R.A.5
  • 46
    • 0035863867 scopus 로고    scopus 로고
    • The role of IL-10 in promoting disease progression in Leishmaniasis
    • Kane M.M., Mosser D.M. The role of IL-10 in promoting disease progression in Leishmaniasis. J. Immunol. 166:2001;1141-1147.
    • (2001) J. Immunol. , vol.166 , pp. 1141-1147
    • Kane, M.M.1    Mosser, D.M.2
  • 48
    • 0031255049 scopus 로고    scopus 로고
    • Characterization of T-cell mediated responses in nonhealing and healing Leishmania major infections in the absence of endogenous IL-4
    • Kropf P., Etges R., Schopf L., Chung C., Sypek J., Muller I. Characterization of T-cell mediated responses in nonhealing and healing Leishmania major infections in the absence of endogenous IL-4. J. Immunol. 159:1997;3434-3443.
    • (1997) J. Immunol. , vol.159 , pp. 3434-3443
    • Kropf, P.1    Etges, R.2    Schopf, L.3    Chung, C.4    Sypek, J.5    Muller, I.6
  • 49
    • 0032729433 scopus 로고    scopus 로고
    • Expression of Th2 cytokines and the stable Th2 marker ST2L in the absence of IL-4 during Leishmania major infection
    • Kropf P., Schopf L.R., Chung C.L., Xu D., Liew F.Y., Sypek J.P., Müller I. Expression of Th2 cytokines and the stable Th2 marker ST2L in the absence of IL-4 during Leishmania major infection. Eur. J. Immunol. 29:1999;3621-3628.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 3621-3628
    • Kropf, P.1    Schopf, L.R.2    Chung, C.L.3    Xu, D.4    Liew, F.Y.5    Sypek, J.P.6    Müller, I.7
  • 50
    • 0028949152 scopus 로고
    • B7-1 and B7-2 costimumatory molecules activate differentially the Th1/ Th2 developmental pathways: Application to autoimmune disease therapy
    • Kuchroo V.K., Das M.P., Brown J.A., Ranger A.M., Zamvil S.S., Sobel R.A., Weiner H.L., Nabavi N., Glimcher L.H. B7-1 and B7-2 costimumatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell. 80:1995;707-718.
    • (1995) Cell , vol.80 , pp. 707-718
    • Kuchroo, V.K.1    Das, M.P.2    Brown, J.A.3    Ranger, A.M.4    Zamvil, S.S.5    Sobel, R.A.6    Weiner, H.L.7    Nabavi, N.8    Glimcher, L.H.9
  • 53
    • 0031114125 scopus 로고    scopus 로고
    • Early production of IL-4 in susceptible mice infected with Leishmania major rapidly induces IL-12 unresponsiveness
    • Launois P., Swihart K., Milon G., Louis J.A. Early production of IL-4 in susceptible mice infected with Leishmania major rapidly induces IL-12 unresponsiveness. J. Immunol. 158:1997;3317-3324.
    • (1997) J. Immunol. , vol.158 , pp. 3317-3324
    • Launois, P.1    Swihart, K.2    Milon, G.3    Louis, J.A.4
  • 54
    • 0036570014 scopus 로고    scopus 로고
    • + T cells in resistant mice treated once with anti-IL-12 or IFN-γ antibodies at the onset of infection with Leishmania major instructs Th2 cell development, resulting in nonhealing lesions
    • + T cells in resistant mice treated once with anti-IL-12 or IFN-γ antibodies at the onset of infection with Leishmania major instructs Th2 cell development, resulting in nonhealing lesions. J. Immunol. 168:2002;4628-4635.
    • (2002) J. Immunol. , vol.168 , pp. 4628-4635
    • Launois, P.1    Gumy, A.2    Himmerlich, H.3    Locksley, R.M.4    Röcken, M.5    Louis, J.A.6
  • 55
  • 56
    • 0033555789 scopus 로고    scopus 로고
    • Anti-TGF-beta treatment promotes rapid healing of Leishmania major infection in mice by enhancing in vivo nitric oxide production
    • Li J., Hunter C.A., Farell J.P. Anti-TGF-beta treatment promotes rapid healing of Leishmania major infection in mice by enhancing in vivo nitric oxide production. J. Immunol. 162:1999;974-979.
    • (1999) J. Immunol. , vol.162 , pp. 974-979
    • Li, J.1    Hunter, C.A.2    Farell, J.P.3
  • 57
    • 0024352297 scopus 로고
    • Macrophage activation by interferon-γ from host-protective T cells is inhibited by interleukin (IL) 3 and IL4 produced by disease-promoting T cells in leishmaniasis
    • Liew F.Y., Millott S., Li Y., Lelchuck R., Chan W.L., Ziltener H. Macrophage activation by interferon-γ from host-protective T cells is inhibited by interleukin (IL) 3 and IL4 produced by disease-promoting T cells in leishmaniasis. Eur. J. Immunol. 19:1989;1227-1232.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 1227-1232
    • Liew, F.Y.1    Millott, S.2    Li, Y.3    Lelchuck, R.4    Chan, W.L.5    Ziltener, H.6
  • 58
    • 0025300228 scopus 로고
    • Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine
    • Liew F.Y., Millott S., Parkinson C., Palmer R.M., Moncada S. Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine. J. Immunol. 144:1990;4794-4797.
    • (1990) J. Immunol. , vol.144 , pp. 4794-4797
    • Liew, F.Y.1    Millott, S.2    Parkinson, C.3    Palmer, R.M.4    Moncada, S.5
  • 59
    • 0023492716 scopus 로고
    • Murine cutaneous leishmaniasis: Susceptibility correlates with differential expansion of helper T cell subset
    • Locksley R.M., Heinzel F.P., Sadick M.D., Holaday B.J., Gardner K.D. Murine cutaneous leishmaniasis: susceptibility correlates with differential expansion of helper T cell subset. Ann. Inst. Pasteur/Immunol. 138:1987;744-749.
    • (1987) Ann. Inst. Pasteur/Immunol. , vol.138 , pp. 744-749
    • Locksley, R.M.1    Heinzel, F.P.2    Sadick, M.D.3    Holaday, B.J.4    Gardner, K.D.5
  • 61
    • 0029996589 scopus 로고    scopus 로고
    • A Vβ4-specific superantigen encoded by a new exogenous mouse mammary tumor virus
    • Maillard I., Erny K., Acha-Orbea H., Diggelmann H. A Vβ4-specific superantigen encoded by a new exogenous mouse mammary tumor virus. Eur. J. Immunol. 26:1996;1000-1006.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1000-1006
    • Maillard, I.1    Erny, K.2    Acha-Orbea, H.3    Diggelmann, H.4
  • 64
    • 0030002111 scopus 로고    scopus 로고
    • Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response
    • Mattner F., Magram J., Ferrante J., Launois P., Di Padova K., Behin R., Gately M.K., Louis J.A., Alber G. Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response. Eur. J. Immunol. 26:1996;1553-1559.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1553-1559
    • Mattner, F.1    Magram, J.2    Ferrante, J.3    Launois, P.4    Di Padova, K.5    Behin, R.6    Gately, M.K.7    Louis, J.A.8    Alber, G.9
  • 65
    • 0025788370 scopus 로고
    • Nitrogen and oxygen metabolites and the killing of Leishmania by activated murine macrophages
    • Mauël J., Betz-Corradin S., Buchmüller Rouiller Y. Nitrogen and oxygen metabolites and the killing of Leishmania by activated murine macrophages. Res. Immunol. 142:1991;577-580.
    • (1991) Res. Immunol. , vol.142 , pp. 577-580
    • Mauël, J.1    Betz-Corradin, S.2    Buchmüller Rouiller, Y.3
  • 67
    • 0019720353 scopus 로고
    • Resistance and abrogation of resistance to cutaneous leishmaniasis in reconstituted BALB/c mice
    • Mitchell G.F., Curtis J.M., Scollay R.G., Handman E. Resistance and abrogation of resistance to cutaneous leishmaniasis in reconstituted BALB/c mice. Aust. J. Exp. Biol. Med. Sci. 59:1981;539-544.
    • (1981) Aust. J. Exp. Biol. Med. Sci. , vol.59 , pp. 539-544
    • Mitchell, G.F.1    Curtis, J.M.2    Scollay, R.G.3    Handman, E.4
  • 68
    • 0027422394 scopus 로고
    • Genetic control of Leishmania major infection in congenic, recombinant inbred and F2 populations of mice
    • Mock B., Blackwell J., Hilgers J., Potter M., Nacy C. Genetic control of Leishmania major infection in congenic, recombinant inbred and F2 populations of mice. Eur. J. Immunogenet. 20:1993;335-348.
    • (1993) Eur. J. Immunogenet. , vol.20 , pp. 335-348
    • Mock, B.1    Blackwell, J.2    Hilgers, J.3    Potter, M.4    Nacy, C.5
  • 69
    • 0034040798 scopus 로고    scopus 로고
    • Genetically resistant mice lacking IL-18 gene develop Th1 response and control cutaneous Leishmania major infection
    • Monteforte G.M., Takeda K., Rodriguez-Sosa M., Akira S., David J.R., Satoskar A.R. Genetically resistant mice lacking IL-18 gene develop Th1 response and control cutaneous Leishmania major infection. J. Immunol. 164:2000;5890-5893.
    • (2000) J. Immunol. , vol.164 , pp. 5890-5893
    • Monteforte, G.M.1    Takeda, K.2    Rodriguez-Sosa, M.3    Akira, S.4    David, J.R.5    Satoskar, A.R.6
  • 70
    • 0034278725 scopus 로고    scopus 로고
    • Dendritic cell regulation of TH1-TH2 development
    • Moser M., Murphy K.M. Dendritic cell regulation of TH1-TH2 development. Nat. Immunol. 1:2000;199-205.
    • (2000) Nat. Immunol. , vol.1 , pp. 199-205
    • Moser, M.1    Murphy, K.M.2
  • 71
    • 0024353079 scopus 로고
    • Th1 and Th2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • Mosmann T.R., Coffman R.L. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:1989;145-173.
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coffman, R.L.2
  • 74
    • 0035337992 scopus 로고    scopus 로고
    • BALB/c mice bearing a transgenic IL-12 receptor β2 gene exhibit a non healing phenotype to Leishmania major infection despite intact IL-12 signaling
    • Nishikomori R., Gurunathan S., Nishikimori K., Strober W. BALB/c mice bearing a transgenic IL-12 receptor β2 gene exhibit a non healing phenotype to Leishmania major infection despite intact IL-12 signaling. J. Immunol. 166:2001;6776-6783.
    • (2001) J. Immunol. , vol.166 , pp. 6776-6783
    • Nishikomori, R.1    Gurunathan, S.2    Nishikimori, K.3    Strober, W.4
  • 75
    • 0030023112 scopus 로고    scopus 로고
    • Susceptibility to Leishmania major infection in IL-4 deficient mice
    • Noben-Trauth N., Kropf P., Muller I. Susceptibility to Leishmania major infection in IL-4 deficient mice. Science. 271:1996;987-990.
    • (1996) Science , vol.271 , pp. 987-990
    • Noben-Trauth, N.1    Kropf, P.2    Muller, I.3
  • 76
    • 0033563135 scopus 로고    scopus 로고
    • IL-4- and IL-4 receptor deficient BALB/c mice reveal differences in susceptibility to Leishmania major parasite substrains
    • Noben-Trauth N., Paul W.E., Sacks D.L. IL-4- and IL-4 receptor deficient BALB/c mice reveal differences in susceptibility to Leishmania major parasite substrains. J. Immunol. 162:1999;6132-6140.
    • (1999) J. Immunol. , vol.162 , pp. 6132-6140
    • Noben-Trauth, N.1    Paul, W.E.2    Sacks, D.L.3
  • 77
    • 0038560975 scopus 로고    scopus 로고
    • The relative contribution of IL-4 receptor signaling and IL-10 to susceptibility to Leishmania major
    • Noben-Trauth N., Lira R., Nagase H., Paul W.E., Sacks D.L. The relative contribution of IL-4 receptor signaling and IL-10 to susceptibility to Leishmania major. J. Immunol. 170:2003;5152-5158.
    • (2003) J. Immunol. , vol.170 , pp. 5152-5158
    • Noben-Trauth, N.1    Lira, R.2    Nagase, H.3    Paul, W.E.4    Sacks, D.L.5
  • 78
    • 0036079651 scopus 로고    scopus 로고
    • Regulation of Th1 differentiation-controlling the controllers
    • O'Shea J.J., Paul W.E. Regulation of Th1 differentiation-controlling the controllers. Nat. Immunol. 3:2002;506-508.
    • (2002) Nat. Immunol. , vol.3 , pp. 506-508
    • O'Shea, J.J.1    Paul, W.E.2
  • 84
    • 0033732322 scopus 로고    scopus 로고
    • A targeted mutation in the IL4Ralpha gene protects mice against autoimmune diabetes
    • Radu D.L., Noben-Trauth N., Hu-Li J., Paul W.E., Bona C.A. A targeted mutation in the IL4Ralpha gene protects mice against autoimmune diabetes. Proc. Natl. Acad. Sci. USA. 97:2000;12700-12704.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 12700-12704
    • Radu, D.L.1    Noben-Trauth, N.2    Hu-Li, J.3    Paul, W.E.4    Bona, C.A.5
  • 85
    • 0028172588 scopus 로고
    • Differential ability of Th1 and Th2 T cells to express Fas ligand and to undergo activation-induced cell death
    • Ramsdell F., Seaman M., Miller R., Picha K., Kennedy M., Lynch D. Differential ability of Th1 and Th2 T cells to express Fas ligand and to undergo activation-induced cell death. Int. Immunol. 6:1994;1545-1553.
    • (1994) Int. Immunol. , vol.6 , pp. 1545-1553
    • Ramsdell, F.1    Seaman, M.2    Miller, R.3    Picha, K.4    Kennedy, M.5    Lynch, D.6
  • 87
    • 0027485741 scopus 로고
    • Mapping of genes controlling Leishmania major infection in CXS recombinant inbred mice
    • Roberts M., Mock B.A., Blackwell J.M. Mapping of genes controlling Leishmania major infection in CXS recombinant inbred mice. Eur. J. Immunogenet. 20:1993;349-362.
    • (1993) Eur. J. Immunogenet. , vol.20 , pp. 349-362
    • Roberts, M.1    Mock, B.A.2    Blackwell, J.M.3
  • 88
    • 0036065808 scopus 로고    scopus 로고
    • Further checkpoints in Th1 development
    • Robinson D.S., O'Garra A. Further checkpoints in Th1 development. Immunity. 16:2002;755-758.
    • (2002) Immunity , vol.16 , pp. 755-758
    • Robinson, D.S.1    O'Garra, A.2
  • 91
    • 0036831673 scopus 로고    scopus 로고
    • The immunology of susceptibility and resistance to Leishmania major in mice
    • Sacks D., Noben-Trauth N. The immunology of susceptibility and resistance to Leishmania major in mice. Nat. Rev. Immunol. 2:2002;845-858.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 845-858
    • Sacks, D.1    Noben-Trauth, N.2
  • 92
    • 0025133974 scopus 로고
    • Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon-γ independent mechanism
    • Sadick M.D., Heinzel F.P., Holaday B.J., Pu R.T., Dawkins R.S., Locksley R.M. Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon-γ independent mechanism. J. Exp. Med. 171:1990;115-127.
    • (1990) J. Exp. Med. , vol.171 , pp. 115-127
    • Sadick, M.D.1    Heinzel, F.P.2    Holaday, B.J.3    Pu, R.T.4    Dawkins, R.S.5    Locksley, R.M.6
  • 93
    • 0028031832 scopus 로고
    • Development and proliferation of lymphocytes in mice deficient for both interleukin-2 and -4
    • Sadlack B., Kuhn R., Schorle H., Rajewsky K., Muller W., Horak I. Development and proliferation of lymphocytes in mice deficient for both interleukin-2 and -4. Eur. J. Immunol. 24:1994;281-284.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 281-284
    • Sadlack, B.1    Kuhn, R.2    Schorle, H.3    Rajewsky, K.4    Muller, W.5    Horak, I.6
  • 96
    • 0029077326 scopus 로고
    • IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis
    • Scharton-Kersten T., Afonso L.C.C., Wysocka M., Trinchieri G., Scott P. IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis. J. Immunol. 154:1995;5320-5330.
    • (1995) J. Immunol. , vol.154 , pp. 5320-5330
    • Scharton-Kersten, T.1    Afonso, L.C.C.2    Wysocka, M.3    Trinchieri, G.4    Scott, P.5
  • 97
    • 0025899598 scopus 로고
    • Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting
    • Schorle H., Holtschke T., Hunig T., Schimpl A., Horak I. Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting. Nature. 352:1991;621-624.
    • (1991) Nature , vol.352 , pp. 621-624
    • Schorle, H.1    Holtschke, T.2    Hunig, T.3    Schimpl, A.4    Horak, I.5
  • 98
    • 0345628580 scopus 로고    scopus 로고
    • T helper cell type 1-associated and cytotoxic T lymphocyte-mediated tumor immunity is impaired in interleukin-4 deficient mice
    • Schuler T., Qin Z., Ibne S., Noben-Trauth N., Blankenstein T. T helper cell type 1-associated and cytotoxic T lymphocyte-mediated tumor immunity is impaired in interleukin-4 deficient mice. J. Exp. Med. 189:1999;803-810.
    • (1999) J. Exp. Med. , vol.189 , pp. 803-810
    • Schuler, T.1    Qin, Z.2    Ibne, S.3    Noben-Trauth, N.4    Blankenstein, T.5
  • 99
    • 0026056142 scopus 로고
    • IFN-γ modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis
    • Scott P.A. IFN-γ modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis. J. Immunol. 147:1991;3149-3155.
    • (1991) J. Immunol. , vol.147 , pp. 3149-3155
    • Scott, P.A.1
  • 100
    • 0024236111 scopus 로고
    • Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens
    • Scott P., Natovitz P., Coffman R.L., Pearce E., Sher A. Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens. J. Exp. Med. 168:1988;1675-1684.
    • (1988) J. Exp. Med. , vol.168 , pp. 1675-1684
    • Scott, P.1    Natovitz, P.2    Coffman, R.L.3    Pearce, E.4    Sher, A.5
  • 101
    • 0028123444 scopus 로고
    • CD28-mediated costimulation of interleukin 2(IL-2) production plays a critical role in T cell priming for IL-4 and interferon γ production
    • Seder R.A., Germain R.N., Linsley P.S., Paul W.E. CD28-mediated costimulation of interleukin 2(IL-2) production plays a critical role in T cell priming for IL-4 and interferon γ production. J. Exp. Med. 179:1994;299-304.
    • (1994) J. Exp. Med. , vol.179 , pp. 299-304
    • Seder, R.A.1    Germain, R.N.2    Linsley, P.S.3    Paul, W.E.4
  • 102
    • 0036597371 scopus 로고    scopus 로고
    • + suppressor T cells: More question than answers
    • + suppressor T cells: more question than answers. Nat. Rev. Immunol. 2:2002;389-400.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 389-400
    • Shevach, E.M.1
  • 103
    • 0032882699 scopus 로고    scopus 로고
    • Regulation of the IL-12/IL-12R axis: A critical step in T-helper cell differentiation and effector function
    • Sinigaglia F., D'Ambrosio D., Panina-Bordignon P., Rogge L. Regulation of the IL-12/IL-12R axis: a critical step in T-helper cell differentiation and effector function. Immunol. Rev. 170:1999;65-72.
    • (1999) Immunol. Rev. , vol.170 , pp. 65-72
    • Sinigaglia, F.1    D'Ambrosio, D.2    Panina-Bordignon, P.3    Rogge, L.4
  • 104
    • 0023907493 scopus 로고
    • Interleukin-2: Inception, impact and implications
    • Smith K.A. Interleukin-2: inception, impact and implications. Science. 240:1988;1169-1176.
    • (1988) Science , vol.240 , pp. 1169-1176
    • Smith, K.A.1
  • 107
    • 0028129526 scopus 로고
    • Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major
    • Stenger S., Thüring H., Röllinghoff M., Bogdan C. Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major. J. Exp. Med. 180:1994;783-793.
    • (1994) J. Exp. Med. , vol.180 , pp. 783-793
    • Stenger, S.1    Thüring, H.2    Röllinghoff, M.3    Bogdan, C.4
  • 108
    • 0036669784 scopus 로고    scopus 로고
    • Rapid expansion and IL-4 expression by Leishmania-specific naive helper T cells in vivo
    • Stetson D.B., Mohrs M., Mallet-Designe V., Teyton L., Locksley R.M. Rapid expansion and IL-4 expression by Leishmania-specific naive helper T cells in vivo. Immunity. 17:2002;191-200.
    • (2002) Immunity , vol.17 , pp. 191-200
    • Stetson, D.B.1    Mohrs, M.2    Mallet-Designe, V.3    Teyton, L.4    Locksley, R.M.5
  • 109
    • 0025222698 scopus 로고
    • IL-4 directs the development of Th2-like helper effectors
    • Swain S.L., Weinberg A.D., English M., Huston G. IL-4 directs the development of Th2-like helper effectors. J. Immunol. 145:1990;3796-3806.
    • (1990) J. Immunol. , vol.145 , pp. 3796-3806
    • Swain, S.L.1    Weinberg, A.D.2    English, M.3    Huston, G.4
  • 112
    • 0029071483 scopus 로고
    • Developmental commitment to the Th2 lineage by extinction of IL-12 signaling
    • Szabo S.J., Jacobson N.G., Dighe A.S., Gübler U., Murphy K.M. Developmental commitment to the Th2 lineage by extinction of IL-12 signaling. Immunity. 2:1995;665-675.
    • (1995) Immunity , vol.2 , pp. 665-675
    • Szabo, S.J.1    Jacobson, N.G.2    Dighe, A.S.3    Gübler, U.4    Murphy, K.M.5
  • 113
    • 0037059462 scopus 로고    scopus 로고
    • Distinct effects of T-bet in Th1 lineage commitment and IFN-γ production in CD4 and CD8 T cells
    • Szabo S.J., Sullivan B.M., Stemmann C., Satoskar A.R., Sleckman B.P., Glimcher L.H. Distinct effects of T-bet in Th1 lineage commitment and IFN-γ production in CD4 and CD8 T cells. Science. 295:2002;338-342.
    • (2002) Science , vol.295 , pp. 338-342
    • Szabo, S.J.1    Sullivan, B.M.2    Stemmann, C.3    Satoskar, A.R.4    Sleckman, B.P.5    Glimcher, L.H.6
  • 114
    • 0024502120 scopus 로고
    • Murine interleukin-4 displays potent anti-tumor activity in vivo
    • Tepper R.I., Pattengale P.K., Leder P. Murine interleukin-4 displays potent anti-tumor activity in vivo. Cell. 57:1989;503-512.
    • (1989) Cell , vol.57 , pp. 503-512
    • Tepper, R.I.1    Pattengale, P.K.2    Leder, P.3
  • 116
    • 0032962127 scopus 로고    scopus 로고
    • Inhibition of allergic contact dermatitis to DNCB but not oxazolone in interleukin-4-deficient mice
    • Traidl C., Jugert F., Krieg T., Merk H., Hunzelmann N. Inhibition of allergic contact dermatitis to DNCB but not oxazolone in interleukin-4- deficient mice. J. Invest. Dermatol. 112:1999;476-482.
    • (1999) J. Invest. Dermatol. , vol.112 , pp. 476-482
    • Traidl, C.1    Jugert, F.2    Krieg, T.3    Merk, H.4    Hunzelmann, N.5
  • 117
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
    • Trinchieri G. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 13:1995;251-276.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 251-276
    • Trinchieri, G.1
  • 119
    • 0028326103 scopus 로고
    • + effector cells default to the Th2 pathway in interferon γ-deficient mice infected with Leishmania major
    • + effector cells default to the Th2 pathway in interferon γ-deficient mice infected with Leishmania major. J. Exp. Med. 179:1994;1367-1371.
    • (1994) J. Exp. Med. , vol.179 , pp. 1367-1371
    • Wang, Z.-E.1    Reiner, S.L.2    Zheng, S.3    Dalton, D.K.4    Locksley, R.M.5
  • 120
    • 0025875022 scopus 로고
    • Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biological effect on T and natural killer cells
    • Wolf S.F., Temple P.A., Kobayashi M., Young D., Dicig M., Lowe L., Dzialo R., Fitz L., Ferenz C., Hewick R.M. Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biological effect on T and natural killer cells. J. Immunol. 146:1991;3074-3081.
    • (1991) J. Immunol. , vol.146 , pp. 3074-3081
    • Wolf, S.F.1    Temple, P.A.2    Kobayashi, M.3    Young, D.4    Dicig, M.5    Lowe, L.6    Dzialo, R.7    Fitz, L.8    Ferenz, C.9    Hewick, R.M.10
  • 121


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.