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Volumn 17, Issue 42008, 1998, Pages 1-52

Interleukin-4 and lnterleukin-13: Their Similarities and Discrepancies

Author keywords

IL 13 receptor; IL 4 receptor; Interleukin 13; Interleukin 4; T lymphocytes

Indexed keywords

IL13RA1 PROTEIN, HUMAN; INTERLEUKIN 13; INTERLEUKIN 13 RECEPTOR; INTERLEUKIN 13 RECEPTOR ALPHA1; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR; INTERLEUKIN RECEPTOR;

EID: 0032442862     PISSN: 08830185     EISSN: 15635244     Source Type: Journal    
DOI: 10.3109/08830189809084486     Document Type: Article
Times cited : (279)

References (300)
  • 3
    • 0042927891 scopus 로고
    • Isolation and characterization of a human inter-leukin cDNA clone, homologous to mouse B-cell stimulatory factor 1, that expresses B-cell-stimulatory activities
    • Yokota T., Otsuka T., Mosmann T., Banchereau J., Defrance T., Blanchard D., de Vries J. E., Lee F., Arai K. Isolation and characterization of a human inter-leukin cDNA clone, homologous to mouse B-cell stimulatory factor 1, that expresses B-cell-stimulatory activities. Proc. Natl. Acad. Sci. USA 1986; 83: 5894 – 5898
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 5894-5898
    • Yokota, T.1    Otsuka, T.2    Mosmann, T.3    Banchereau, J.4    Defrance, T.5    Blanchard, D.6    de Vries, J.E.7    Lee, F.8    Arai, K.9
  • 4
    • 0024559126 scopus 로고
    • A family of small inducible proteins secreted by leukocytes are members of a new superfamily that includes leukocyte and fibroblast-derived inflammatory agents, growth factors, and indicators of various activation process
    • Brown K. D., Zurawski S. M., Mosmann T. R., Zurawski G. A family of small inducible proteins secreted by leukocytes are members of a new superfamily that includes leukocyte and fibroblast-derived inflammatory agents, growth factors, and indicators of various activation process. J. Immunol. 1989; 142: 679 – 687
    • (1989) J. Immunol. , vol.142 , pp. 679-687
    • Brown, K.D.1    Zurawski, S.M.2    Mosmann, T.R.3    Zurawski, G.4
  • 7
    • 0027143034 scopus 로고
    • The immunobiology of interleukin 4
    • O'Garra A., Spits H. The immunobiology of interleukin 4. Res. Immunol. 1993; 144: 567 – 643
    • (1993) Res. Immunol. , vol.144 , pp. 567-643
    • O'Garra, A.1    Spits, H.2
  • 8
    • 0031014560 scopus 로고    scopus 로고
    • Functions of IL-4 and control of its expression
    • Brown M. A., Hural J. Functions of IL-4 and control of its expression. Crit. Rev. Immunol. 1997; 17: 1 – 32
    • (1997) Crit. Rev. Immunol. , vol.17 , pp. 1-32
    • Brown, M.A.1    Hural, J.2
  • 9
    • 0028176655 scopus 로고
    • Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells
    • Zurawski G., de Vries J. E. Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells. Immunol. Today 1994; 15: 19 – 26
    • (1994) Immunol. Today , vol.15 , pp. 19-26
    • Zurawski, G.1    de Vries, J.E.2
  • 11
    • 0027274890 scopus 로고
    • Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction
    • Zurawski S. M., Vega F., Jr., Huyghe B., Zurawski G. Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction. EMBO J. 1993; 12: 2663 – 2670
    • (1993) EMBO J. , vol.12 , pp. 2663-2670
    • Zurawski, S.M.1    Vega, F.2    Huyghe, B.3    Zurawski, G.4
  • 12
    • 0027884911 scopus 로고
    • Identification of an alternatively spliced transcript of human interleukin-4 lacking the sequence encoded by exon 2
    • Sorg R. V., Enczmann J., Sorg U. R., Schneider E. M., Wernet P. Identification of an alternatively spliced transcript of human interleukin-4 lacking the sequence encoded by exon 2. Exp. Hematol. 1993; 21: 560 – 563
    • (1993) Exp. Hematol. , vol.21 , pp. 560-563
    • Sorg, R.V.1    Enczmann, J.2    Sorg, U.R.3    Schneider, E.M.4    Wernet, P.5
  • 13
    • 0030052465 scopus 로고    scopus 로고
    • An alternative splice variant of human IL-4, IL-4 delta 2, inhibits IL-4-stimulated T cell proliferation
    • Atamas S. P., Choi J., Yurovsky V. V., White B. An alternative splice variant of human IL-4, IL-4 delta 2, inhibits IL-4-stimulated T cell proliferation. J. Immunol. 1996; 156: 435 – 441
    • (1996) J. Immunol. , vol.156 , pp. 435-441
    • Atamas, S.P.1    Choi, J.2    Yurovsky, V.V.3    White, B.4
  • 14
    • 0027435159 scopus 로고
    • An interleukin 4 (IL-4) mutant protein inhibits both IL-4 or IL-13-induced human immunoglobulin G4 (IgG4) and IgE synthesis and B cell proliferation: support for a common component shared by IL-4 and IL-13 receptors
    • Aversa G., Punnonen J., Cocks B. J., de Waal Malefyt R., Vega F., Zurawski S. M., Zurawski G., de Vries J. E. An interleukin 4 (IL-4) mutant protein inhibits both IL-4 or IL-13-induced human immunoglobulin G4 (IgG4) and IgE synthesis and B cell proliferation: support for a common component shared by IL-4 and IL-13 receptors. J. Exp. Med. 1993; 178: 2213 – 2218
    • (1993) J. Exp. Med. , vol.178 , pp. 2213-2218
    • Aversa, G.1    Punnonen, J.2    Cocks, B.J.3    de Waal Malefyt, R.4    Vega, F.5    Zurawski, S.M.6    Zurawski, G.7    de Vries, J.E.8
  • 15
    • 0026731478 scopus 로고
    • Conversion of human interleukin-4 into a high affinity antagonist by a single amino acid replacement
    • Kruse N., Tony H. P., Sebald W. Conversion of human interleukin-4 into a high affinity antagonist by a single amino acid replacement. EMBO J. 1992; 11: 3237 – 3244
    • (1992) EMBO J. , vol.11 , pp. 3237-3244
    • Kruse, N.1    Tony, H.P.2    Sebald, W.3
  • 19
    • 0026764439 scopus 로고
    • Three-dimensional solution structure of human interleukin-4 by multidimensional heteronuclear magnetic resonance spectroscopy
    • Powers R., Garrett D. S., March C. J., Frieden E. A., Gronenborn A. M., Clore G. M. Three-dimensional solution structure of human interleukin-4 by multidimensional heteronuclear magnetic resonance spectroscopy. Science 1992; 256: 1673 – 1677
    • (1992) Science , vol.256 , pp. 1673-1677
    • Powers, R.1    Garrett, D.S.2    March, C.J.3    Frieden, E.A.4    Gronenborn, A.M.5    Clore, G.M.6
  • 20
    • 0026731946 scopus 로고
    • The selective isolation of novel cDNAs encoded by the regions surrounding the human interleukin 4 and 5 genes
    • Morgan J. G., Dolganov G. M., Robbins S. E., Hinton L. M., Lovett M. The selective isolation of novel cDNAs encoded by the regions surrounding the human interleukin 4 and 5 genes. Nucleic Acids Res. 1992; 20: 5173 – 5179
    • (1992) Nucleic Acids Res. , vol.20 , pp. 5173-5179
    • Morgan, J.G.1    Dolganov, G.M.2    Robbins, S.E.3    Hinton, L.M.4    Lovett, M.5
  • 21
    • 0028910112 scopus 로고
    • Tandem arrangement of human genes for interleukin-4 and interleukin-13: resemblance in their organization
    • Smirnov D. V., Smirnova M. G., Korobko V. G., Frolova E. I. Tandem arrangement of human genes for interleukin-4 and interleukin-13: resemblance in their organization. Gene 1995; 155: 277 – 281
    • (1995) Gene , vol.155 , pp. 277-281
    • Smirnov, D.V.1    Smirnova, M.G.2    Korobko, V.G.3    Frolova, E.I.4
  • 22
    • 0026552626 scopus 로고
    • An 11-base-pair DNA sequence motif apparently unique to the human interleukin 4 gene confers responsiveness to T-cell activation signals
    • Abe E., de Waal Malefyt R., Matsuda I., Arai K., Arai N. An 11-base-pair DNA sequence motif apparently unique to the human interleukin 4 gene confers responsiveness to T-cell activation signals. Proc. Natl. Acad. Sci. USA 1992; 89: 2864 – 2868
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 2864-2868
    • Abe, E.1    de Waal Malefyt, R.2    Matsuda, I.3    Arai, K.4    Arai, N.5
  • 23
    • 0027305687 scopus 로고
    • Identification of cis-acting regulatory elements controlling interleukin-4 gene expression in T cells
    • Szabo S. J., Gold J. S., Murphy T. L., Murphy K. M. Identification of cis-acting regulatory elements controlling interleukin-4 gene expression in T cells. Mol. Cell. Biol. 1993; 13: 4793 – 4805
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4793-4805
    • Szabo, S.J.1    Gold, J.S.2    Murphy, T.L.3    Murphy, K.M.4
  • 24
    • 0029995279 scopus 로고    scopus 로고
    • Coexpression of the interleukin-13 and interleukin-4 genes correlates with their physical linkage in the cytokine gene cluster on human chromosome 5q23–31
    • Dolganov G., Bort S., Lovett M., Burr J., Schubert L., Short D., McGurn M., Gibson C., Lewis D. B. Coexpression of the interleukin-13 and interleukin-4 genes correlates with their physical linkage in the cytokine gene cluster on human chromosome 5q23–31. Blood 1996; 87: 3316 – 3326
    • (1996) Blood , vol.87 , pp. 3316-3326
    • Dolganov, G.1    Bort, S.2    Lovett, M.3    Burr, J.4    Schubert, L.5    Short, D.6    McGurn, M.7    Gibson, C.8    Lewis, D.B.9
  • 25
    • 0031567889 scopus 로고    scopus 로고
    • Identification of IL-4 promoter elements conferring Th2-restricted expression during T helper cell subset development
    • Wenner C. A., Szabo S. J., Murphy K. M. Identification of IL-4 promoter elements conferring Th2-restricted expression during T helper cell subset development. J. Immunol. 1997; 158: 765 – 773
    • (1997) J. Immunol. , vol.158 , pp. 765-773
    • Wenner, C.A.1    Szabo, S.J.2    Murphy, K.M.3
  • 27
    • 0027275095 scopus 로고
    • A novel enhancer element in the human IL-4 promoter is suppressed by a position-independent silencer
    • Li-Weber M., Krafft H., Krammer P. H. A novel enhancer element in the human IL-4 promoter is suppressed by a position-independent silencer. J. Immunol. 1993; 151: 1371 – 1382
    • (1993) J. Immunol. , vol.151 , pp. 1371-1382
    • Li-Weber, M.1    Krafft, H.2    Krammer, P.H.3
  • 28
    • 0031068113 scopus 로고    scopus 로고
    • Differential interaction of nuclear factors with the PRE-I enhancer element of the human IL-4 promoter in different T cell subsets
    • Li-Weber M., Salgame P., Hu C., Davydov I. V., Krammer P. H. Differential interaction of nuclear factors with the PRE-I enhancer element of the human IL-4 promoter in different T cell subsets. J. Immunol. 1997; 158: 1194 – 1200
    • (1997) J. Immunol. , vol.158 , pp. 1194-1200
    • Li-Weber, M.1    Salgame, P.2    Hu, C.3    Davydov, I.V.4    Krammer, P.H.5
  • 29
    • 0029030775 scopus 로고
    • Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene
    • Rooney J. W., Hoey T., Glimcher L. H. Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene. Immunity 1995; 2: 473 – 483
    • (1995) Immunity , vol.2 , pp. 473-483
    • Rooney, J.W.1    Hoey, T.2    Glimcher, L.H.3
  • 30
    • 0030030331 scopus 로고    scopus 로고
    • Polymorphic nucleotides within the human IL-4 promoter that mediate overexpression of the gene
    • Song Z., Casolaro V., Chen R., Georas S. N., Monos D., Ono S. J. Polymorphic nucleotides within the human IL-4 promoter that mediate overexpression of the gene. J. Immunol. 1996; 156: 424 – 429
    • (1996) J. Immunol. , vol.156 , pp. 424-429
    • Song, Z.1    Casolaro, V.2    Chen, R.3    Georas, S.N.4    Monos, D.5    Ono, S.J.6
  • 31
    • 0027985435 scopus 로고
    • Role of NF-Y and IRF-2 in the regulation of human IL-4 gene expression
    • Li-Weber M., Davydov I. V., Krafft H., Krammer P. H. Role of NF-Y and IRF-2 in the regulation of human IL-4 gene expression. J. Immunol. 1994; 153: 4122 – 4133
    • (1994) J. Immunol. , vol.153 , pp. 4122-4133
    • Li-Weber, M.1    Davydov, I.V.2    Krafft, H.3    Krammer, P.H.4
  • 33
    • 0023178658 scopus 로고
    • Characterization of the human B cell stimulatory factor 1 receptor
    • Park L. S., Friend D., Sassenfeld H. M., Urdal D. L. Characterization of the human B cell stimulatory factor 1 receptor. J. Exp. Med. 1987; 166: 476 – 488
    • (1987) J. Exp. Med. , vol.166 , pp. 476-488
    • Park, L.S.1    Friend, D.2    Sassenfeld, H.M.3    Urdal, D.L.4
  • 34
    • 0031568012 scopus 로고    scopus 로고
    • The IL-13 receptor structure differs on various cell types and may share more than one component with IL-4 receptor
    • Obiri N. I., Leland P., Murata T., Debinski W., Puri R. K. The IL-13 receptor structure differs on various cell types and may share more than one component with IL-4 receptor. J. Immunol. 1997; 158: 756 – 764
    • (1997) J. Immunol. , vol.158 , pp. 756-764
    • Obiri, N.I.1    Leland, P.2    Murata, T.3    Debinski, W.4    Puri, R.K.5
  • 35
    • 0029032061 scopus 로고
    • The IL-2 receptor 7c chain does not function as a subunit shared by the IL-4 and IL-13 receptors. Implication for the structure of the IL-4 receptor
    • He Y. W., Malek T. R. The IL-2 receptor 7c chain does not function as a subunit shared by the IL-4 and IL-13 receptors. Implication for the structure of the IL-4 receptor. J. Immunol 1995; 155: 9 – 12
    • (1995) J. Immunol , vol.155 , pp. 9-12
    • He, Y.W.1    Malek, T.R.2
  • 37
    • 0024430130 scopus 로고
    • Identification of interleukin-4 receptor-associated proteins and expression of both high and low affinity binding on human lymphoid cells
    • Foxwell B. M.J., Woerly G., Ryffel B. Identification of interleukin-4 receptor-associated proteins and expression of both high and low affinity binding on human lymphoid cells. Eur. J. Immunol. 1989; 19: 1637 – 1641
    • (1989) Eur. J. Immunol. , vol.19 , pp. 1637-1641
    • Foxwell, B.M.J.1    Woerly, G.2    Ryffel, B.3
  • 39
    • 0025762023 scopus 로고
    • A recombinant extracellular domain of the human interleukin 4 receptor inhibits the biological effects of interleukin 4 on T and B lymphocytes
    • Garrone P., Djossou O., Galizzi J. P., Banchereau J. A recombinant extracellular domain of the human interleukin 4 receptor inhibits the biological effects of interleukin 4 on T and B lymphocytes. Eur. J. Immunol. 1991; 21: 1365 – 1369
    • (1991) Eur. J. Immunol. , vol.21 , pp. 1365-1369
    • Garrone, P.1    Djossou, O.2    Galizzi, J.P.3    Banchereau, J.4
  • 43
    • 0028219966 scopus 로고
    • An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth
    • Keegan A. D., Nelms K., White M., Wang L. M., Pierce J. H., Paul W. E. An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth. Cell 1994; 76: 811 – 820
    • (1994) Cell , vol.76 , pp. 811-820
    • Keegan, A.D.1    Nelms, K.2    White, M.3    Wang, L.M.4    Pierce, J.H.5    Paul, W.E.6
  • 44
    • 0027751556 scopus 로고
    • Interleukin-2 receptor γ chain: a functional component of the interleukin-7 receptor
    • Noguchi M., Nakamura Y., Russel S. M., Ziegler S. F., Tsang M., Cao X., Leonard W. J. Interleukin-2 receptor γ chain: a functional component of the interleukin-7 receptor. Science 1993; 262: 1877 – 1880
    • (1993) Science , vol.262 , pp. 1877-1880
    • Noguchi, M.1    Nakamura, Y.2    Russel, S.M.3    Ziegler, S.F.4    Tsang, M.5    Cao, X.6    Leonard, W.J.7
  • 47
    • 0028962572 scopus 로고
    • The role of shared receptor motifs and common stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13 and IL-15
    • Lin J. X., Migone T. S., Tsang M., Friedmann M., Weatherbee J. A., Zhou L., Yamauchi A., Bloom E. T., Mietz J., John S., Leonard W. J. The role of shared receptor motifs and common stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13 and IL-15. Immunity 1995; 2: 331 – 339
    • (1995) Immunity , vol.2 , pp. 331-339
    • Lin, J.X.1    Migone, T.S.2    Tsang, M.3    Friedmann, M.4    Weatherbee, J.A.5    Zhou, L.6    Yamauchi, A.7    Bloom, E.T.8    Mietz, J.9    John, S.10    Leonard, W.J.11
  • 49
    • 0028917463 scopus 로고
    • Receptor for interleukin 13. Interaction with interleukin 4 by a mechanism that does not involve the common γ chain shared by receptors for Interleukins 2, 4, 7, 9 and 15
    • Obiri N. I., Debinski W., Leonard W. J., Puri R. K. Receptor for interleukin 13. Interaction with interleukin 4 by a mechanism that does not involve the common γ chain shared by receptors for Interleukins 2, 4, 7, 9 and 15. J. Biol. Chem. 1995; 270: 8797 – 8804
    • (1995) J. Biol. Chem. , vol.270 , pp. 8797-8804
    • Obiri, N.I.1    Debinski, W.2    Leonard, W.J.3    Puri, R.K.4
  • 50
    • 0028898492 scopus 로고
    • Characterization and comparison of the Interleukin 13 receptor with the interleukin 4 receptor on several cell types
    • Vita N., Lefort S., Laurent P., Caput D., Ferrara P. Characterization and comparison of the Interleukin 13 receptor with the interleukin 4 receptor on several cell types. J. Biol. Chem. 1995; 270: 3512 – 3517
    • (1995) J. Biol. Chem. , vol.270 , pp. 3512-3517
    • Vita, N.1    Lefort, S.2    Laurent, P.3    Caput, D.4    Ferrara, P.5
  • 51
    • 0028797453 scopus 로고
    • Function of the Interleukin-2 (IL-2) receptor γ-chain in biologic responses of X-linked severe combined immunodeficient B cells to IL-2, IL-4, IL-13 and IL-15
    • Matthews D. J., Clark P. A., Herbert J., Morgan G., Armitage R. J., Kinnon C., Minty A., Grabstein K. H., Caput D., Ferrara P., Callard R. Function of the Interleukin-2 (IL-2) receptor γ-chain in biologic responses of X-linked severe combined immunodeficient B cells to IL-2, IL-4, IL-13 and IL-15. Blood 1995; 85: 38 – 42
    • (1995) Blood , vol.85 , pp. 38-42
    • Matthews, D.J.1    Clark, P.A.2    Herbert, J.3    Morgan, G.4    Armitage, R.J.5    Kinnon, C.6    Minty, A.7    Grabstein, K.H.8    Caput, D.9    Ferrara, P.10    Callard, R.11
  • 52
    • 0028909292 scopus 로고
    • Both interleukin 4 and interleukin 13 induce tyrosine phosphorylation of the 140-kDa subunit of the interleukin 4 receptor
    • Smerz-Bertling C., Duschl A. Both interleukin 4 and interleukin 13 induce tyrosine phosphorylation of the 140-kDa subunit of the interleukin 4 receptor. J. Biol. Chem. 1995; 270: 966 – 970
    • (1995) J. Biol. Chem. , vol.270 , pp. 966-970
    • Smerz-Bertling, C.1    Duschl, A.2
  • 53
    • 0030068217 scopus 로고    scopus 로고
    • Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor
    • Hilton D. J., Zhang J. G., Metcalf D., Alexander W. S., Nicola N. A., Willson T. A. Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor. Proc. Natl. Acad. Sci. USA 1996; 93: 497 – 501
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 497-501
    • Hilton, D.J.1    Zhang, J.G.2    Metcalf, D.3    Alexander, W.S.4    Nicola, N.A.5    Willson, T.A.6
  • 54
    • 10544246077 scopus 로고    scopus 로고
    • cDNA cloning and characterization of the human interleukin 13 receptor α chain
    • Aman M. J., Tayebi N., Obiri N., Puri R. K., Modi W. S., Leonard W. J. cDNA cloning and characterization of the human interleukin 13 receptor α chain. J. Biol. Chem. 1996; 271: 29265 – 29270
    • (1996) J. Biol. Chem. , vol.271 , pp. 29265-29270
    • Aman, M.J.1    Tayebi, N.2    Obiri, N.3    Puri, R.K.4    Modi, W.S.5    Leonard, W.J.6
  • 56
    • 0028815074 scopus 로고
    • IL-13 selectively induces vascular cell adhesion molecule-1 expression in human endothelial cells
    • Bochner B. S., Klunk D. A., Sterbinsky S. A., Coffman R. L., Schleimer R. P. IL-13 selectively induces vascular cell adhesion molecule-1 expression in human endothelial cells. J. Immunol. 1995; 154: 799 – 803
    • (1995) J. Immunol. , vol.154 , pp. 799-803
    • Bochner, B.S.1    Klunk, D.A.2    Sterbinsky, S.A.3    Coffman, R.L.4    Schleimer, R.P.5
  • 57
    • 0029968650 scopus 로고    scopus 로고
    • Interleukin-4 (IL-4) and IL-13 bind to a shared heterodimeric complex on endothelial cells mediating vascular cell adhesion molecule-1 induction in the absence of the common gamma chain
    • Schnyder B., Lugli S., Feng N., Etter H., Lutz R. A., Ryffel B., Sugamura K., Wunderli-Allenspach H., Moser R. Interleukin-4 (IL-4) and IL-13 bind to a shared heterodimeric complex on endothelial cells mediating vascular cell adhesion molecule-1 induction in the absence of the common gamma chain. Blood 1996; 87: 4286 – 4295
    • (1996) Blood , vol.87 , pp. 4286-4295
    • Schnyder, B.1    Lugli, S.2    Feng, N.3    Etter, H.4    Lutz, R.A.5    Ryffel, B.6    Sugamura, K.7    Wunderli-Allenspach, H.8    Moser, R.9
  • 58
    • 0029927153 scopus 로고    scopus 로고
    • Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor α chain
    • Caput D., Laurent P., Kaghad M., Lelias J. M., Lefort S., Vita N., Ferrara P. Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor α chain. J. Biol. Chem. 1996; 271: 16921 – 16926
    • (1996) J. Biol. Chem. , vol.271 , pp. 16921-16926
    • Caput, D.1    Laurent, P.2    Kaghad, M.3    Lelias, J.M.4    Lefort, S.5    Vita, N.6    Ferrara, P.7
  • 59
    • 0030936534 scopus 로고    scopus 로고
    • Interleukin-13 responsiveness and interleukin-13 receptor expression in non-Hodgkin's lymphoma and reactive lymph node B cells. Modulation by CD40 activation
    • Billard C., Caput D., Vita N., Ferrara P., Orrico M., Gaulard P., Boumsell L., Bensussan A., Farcet J. P. Interleukin-13 responsiveness and interleukin-13 receptor expression in non-Hodgkin's lymphoma and reactive lymph node B cells. Modulation by CD40 activation. Eur. Cytokine Netw. 1997; 8: 19 – 27
    • (1997) Eur. Cytokine Netw. , vol.8 , pp. 19-27
    • Billard, C.1    Caput, D.2    Vita, N.3    Ferrara, P.4    Orrico, M.5    Gaulard, P.6    Boumsell, L.7    Bensussan, A.8    Farcet, J.P.9
  • 60
    • 0025362240 scopus 로고
    • A soluble, high-affinity, interleukin-4 binding protein is present in the biological fluids of mice
    • Fernandez-Botran R., Vitetta E. S. A soluble, high-affinity, interleukin-4 binding protein is present in the biological fluids of mice. Proc. Natl. Acad. Sci. USA 1990; 87: 4202 – 4206
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 4202-4206
    • Fernandez-Botran, R.1    Vitetta, E.S.2
  • 61
    • 0030239647 scopus 로고    scopus 로고
    • Two distinct stimulus-dependent pathways lead to production of soluble murine interleukin-4 receptor
    • Blum H., Wolf M., Enssle K., Rollinghoff M., Gessner A. Two distinct stimulus-dependent pathways lead to production of soluble murine interleukin-4 receptor. J. Immunol. 1996; 157: 1846 – 1853
    • (1996) J. Immunol. , vol.157 , pp. 1846-1853
    • Blum, H.1    Wolf, M.2    Enssle, K.3    Rollinghoff, M.4    Gessner, A.5
  • 62
    • 0025902284 scopus 로고
    • Evidence that natural murine soluble interleukin 4 receptors may act as transport proteins
    • Fernandez-Botran R., Vitetta E. S. Evidence that natural murine soluble interleukin 4 receptors may act as transport proteins. J. Exp. Med. 1991; 174: 673 – 681
    • (1991) J. Exp. Med. , vol.174 , pp. 673-681
    • Fernandez-Botran, R.1    Vitetta, E.S.2
  • 66
    • 0030975719 scopus 로고    scopus 로고
    • Identification, purification and characterization of a soluble interleukin (IL)-13-binding protein. Evidence that it is distinct from the cloned il-13 receptor and il-4 receptor alpha-chains
    • Zhang J. G., Hilton D. J., Willson T. A., McFarlane C., Roberts B. A., Moritz R. L., Simpson R. J., Alexander W. S., Metcalf D., Nicola N. A. Identification, purification and characterization of a soluble interleukin (IL)-13-binding protein. Evidence that it is distinct from the cloned il-13 receptor and il-4 receptor alpha-chains. J. Biol. Chem. 1997; 272: 9474 – 9480
    • (1997) J. Biol. Chem. , vol.272 , pp. 9474-9480
    • Zhang, J.G.1    Hilton, D.J.2    Willson, T.A.3    McFarlane, C.4    Roberts, B.A.5    Moritz, R.L.6    Simpson, R.J.7    Alexander, W.S.8    Metcalf, D.9    Nicola, N.A.10
  • 67
    • 0030452008 scopus 로고    scopus 로고
    • IL-4 regulates growth and differentiation by distinct mechanisms
    • Keegan A. D., Ryan J. J., Paul W. E. IL-4 regulates growth and differentiation by distinct mechanisms. The Immunologist 1996; 4: 194 – 198
    • (1996) The Immunologist , vol.4 , pp. 194-198
    • Keegan, A.D.1    Ryan, J.J.2    Paul, W.E.3
  • 68
    • 0027968558 scopus 로고
    • Evidence for a critical role for the cytoplasmic region of the interleukin-2 (IL-2) receptor γ chain in IL-2, IL-4, and IL-7 signalling
    • Kawahara A., Minami Y., Taniguchi T. Evidence for a critical role for the cytoplasmic region of the interleukin-2 (IL-2) receptor γ chain in IL-2, IL-4, and IL-7 signalling. Mol. Cel. Biol. 1994; 14: 5433 – 5440
    • (1994) Mol. Cel. Biol. , vol.14 , pp. 5433-5440
    • Kawahara, A.1    Minami, Y.2    Taniguchi, T.3
  • 69
    • 0027453419 scopus 로고
    • Interleukin-4 (IL-4) induces protein tyrosine phosphorylation of the IL-4 receptor and association of phosphatidylinositol 3-kinase to the IL-4 receptor in a mouse T cell line, HT2
    • Izuhara K., Harada N. Interleukin-4 (IL-4) induces protein tyrosine phosphorylation of the IL-4 receptor and association of phosphatidylinositol 3-kinase to the IL-4 receptor in a mouse T cell line, HT2. J. Biol. Chem. 1993; 268: 13097 – 13102
    • (1993) J. Biol. Chem. , vol.268 , pp. 13097-13102
    • Izuhara, K.1    Harada, N.2
  • 70
    • 0029019017 scopus 로고
    • Interleukin-13 signal transduction in lymphohemopoietic cells. Similarities and differences in signal transduction with interleukin-4 and insulin
    • Welham M. J., Learmonth L., Bone H., Schrader J. W. Interleukin-13 signal transduction in lymphohemopoietic cells. Similarities and differences in signal transduction with interleukin-4 and insulin. J. Biol. Chem. 1995; 270: 12286 – 12296
    • (1995) J. Biol. Chem. , vol.270 , pp. 12286-12296
    • Welham, M.J.1    Learmonth, L.2    Bone, H.3    Schrader, J.W.4
  • 71
    • 0028244396 scopus 로고
    • Involvement of the Jak-3 Janus kinase in signalling by interleukin 2 and 4 in lymphoid and myeloid cells
    • Witthuhn B. A., Silvennoinen O., Miura O., Lai K. S., Cwik C., Liu E. T., Ihle J. N. Involvement of the Jak-3 Janus kinase in signalling by interleukin 2 and 4 in lymphoid and myeloid cells. Nature 1994; 370: 153 – 157
    • (1994) Nature , vol.370 , pp. 153-157
    • Witthuhn, B.A.1    Silvennoinen, O.2    Miura, O.3    Lai, K.S.4    Cwik, C.5    Liu, E.T.6    Ihle, J.N.7
  • 72
    • 0028149328 scopus 로고
    • JAK1 kinase forms complexes with interleukin-4 receptor and 4PS/insulin receptor substrate-1-like protein and is activated by interleukin-4 and interleukin-9 in T lymphocytes
    • Yin T., Tsang M. L.S., Yang Y. C. JAK1 kinase forms complexes with interleukin-4 receptor and 4PS/insulin receptor substrate-1-like protein and is activated by interleukin-4 and interleukin-9 in T lymphocytes. J. Mol. Biol. 1994; 269: 26614 – 26617
    • (1994) J. Mol. Biol. , vol.269 , pp. 26614-26617
    • Yin, T.1    Tsang, M.L.S.2    Yang, Y.C.3
  • 74
    • 0030584699 scopus 로고    scopus 로고
    • IL-13 induces phosphorylation and activation of JAK2 Janus kinase in human colon carcinoma cell lines: similarities between IL-4 and IL-13 signaling
    • Murata T., Noguchi P. D., Puri R. K. IL-13 induces phosphorylation and activation of JAK2 Janus kinase in human colon carcinoma cell lines: similarities between IL-4 and IL-13 signaling. J. Immunol. 1996; 156: 2972 – 2978
    • (1996) J. Immunol. , vol.156 , pp. 2972-2978
    • Murata, T.1    Noguchi, P.D.2    Puri, R.K.3
  • 75
    • 0031068016 scopus 로고    scopus 로고
    • The IL-4- induced tyrosine phosphorylation of the insulin receptor substrate is dependent on JAK-1 expression in human fibrosarcoma cells
    • Wang H. Y., Zamorano J., Yoerkie J. L., Paul W. E., Keegan A. D. The IL-4- induced tyrosine phosphorylation of the insulin receptor substrate is dependent on JAK-1 expression in human fibrosarcoma cells. J. Immunol. 1997; 158: 1037 – 1040
    • (1997) J. Immunol. , vol.158 , pp. 1037-1040
    • Wang, H.Y.1    Zamorano, J.2    Yoerkie, J.L.3    Paul, W.E.4    Keegan, A.D.5
  • 77
    • 0029910989 scopus 로고    scopus 로고
    • IL-4 and IL-13 activate the JAK2 tyrosine kinase and Stat6 in cultured human vascular endothelial cells through a common pathway that does not involve the gamma c chain
    • Palmer-Crocker R. L., Hughes C. C., Pober J. S. IL-4 and IL-13 activate the JAK2 tyrosine kinase and Stat6 in cultured human vascular endothelial cells through a common pathway that does not involve the gamma c chain. J. Clin. Invest. 1996; 98: 604 – 609
    • (1996) J. Clin. Invest. , vol.98 , pp. 604-609
    • Palmer-Crocker, R.L.1    Hughes, C.C.2    Pober, J.S.3
  • 78
    • 0031561791 scopus 로고    scopus 로고
    • Comparison of IL-13 and IL-4-induced signaling in EBV- immortalized human B cells
    • Murata T., Puri R. K. Comparison of IL-13 and IL-4-induced signaling in EBV- immortalized human B cells. Cell. Immunol. 1997; 175: 33 – 40
    • (1997) Cell. Immunol. , vol.175 , pp. 33-40
    • Murata, T.1    Puri, R.K.2
  • 79
    • 0027094764 scopus 로고
    • IL-4 activates a distinct signal transduction cascade from IL-3 in factor-dependent myeloid cells
    • Wang L. M., Keegan A. D., Paul W. E., Heidaran M. A., Gutkind J. S., Pierce J. H. IL-4 activates a distinct signal transduction cascade from IL-3 in factor-dependent myeloid cells. EMBO J. 1992; 11: 4899 – 4908
    • (1992) EMBO J. , vol.11 , pp. 4899-4908
    • Wang, L.M.1    Keegan, A.D.2    Paul, W.E.3    Heidaran, M.A.4    Gutkind, J.S.5    Pierce, J.H.6
  • 80
    • 0028818459 scopus 로고
    • The insulin receptor substrate-1-related 4PS substrate but not the interleukin-2R gamma chain is involved in interleukin-13-mediated signal transduction
    • Wang L. M., Michieli P., Lie W. R., Liu F., Lee C. C., Minty A., Sun X. J., Levine A., White M. F., Pierce J. H. The insulin receptor substrate-1-related 4PS substrate but not the interleukin-2R gamma chain is involved in interleukin-13-mediated signal transduction. Blood 1995; 86: 4218 – 4227
    • (1995) Blood , vol.86 , pp. 4218-4227
    • Wang, L.M.1    Michieli, P.2    Lie, W.R.3    Liu, F.4    Lee, C.C.5    Minty, A.6    Sun, X.J.7    Levine, A.8    White, M.F.9    Pierce, J.H.10
  • 81
    • 0027481642 scopus 로고
    • Human interleukin-4 receptor signalling requires sequences contained within two cytoplasmic regions
    • Koettnitz K., Kalthoff F. S. Human interleukin-4 receptor signalling requires sequences contained within two cytoplasmic regions. Eur. J. Immunol. 1993; 23: 988 – 991
    • (1993) Eur. J. Immunol. , vol.23 , pp. 988-991
    • Koettnitz, K.1    Kalthoff, F.S.2
  • 82
    • 0029997462 scopus 로고    scopus 로고
    • Growth inhibition signalled through the interleukin-4/interleukin-13 receptor complex is associated with tyrosine phosphorylation of insulin receptor substrate-1
    • Schnyder B., Lahm H., Woerly G., Odartchenko N., Ryffel B., Car B. D. Growth inhibition signalled through the interleukin-4/interleukin-13 receptor complex is associated with tyrosine phosphorylation of insulin receptor substrate-1. Biochem. J. 1996; 315: 767 – 774
    • (1996) Biochem. J. , vol.315 , pp. 767-774
    • Schnyder, B.1    Lahm, H.2    Woerly, G.3    Odartchenko, N.4    Ryffel, B.5    Car, B.D.6
  • 83
    • 0026467035 scopus 로고
    • Identification of an essential region for growth signal transduction in the cytoplasmic domain of the human interleukin-4 receptor
    • Harada N., Yang G., Miyajima A., Howard M. Identification of an essential region for growth signal transduction in the cytoplasmic domain of the human interleukin-4 receptor. J. Biol. Chem. 1992; 267: 22752 – 22758
    • (1992) J. Biol. Chem. , vol.267 , pp. 22752-22758
    • Harada, N.1    Yang, G.2    Miyajima, A.3    Howard, M.4
  • 87
    • 0029001660 scopus 로고
    • Components of a Stat recognition code: evidence for two layers of molecular selectivity
    • Schindler U., Wu P., Rothe M., Brasseur M., McKnight S. L. Components of a Stat recognition code: evidence for two layers of molecular selectivity. Immunity 1995; 2: 689 – 697
    • (1995) Immunity , vol.2 , pp. 689-697
    • Schindler, U.1    Wu, P.2    Rothe, M.3    Brasseur, M.4    McKnight, S.L.5
  • 88
    • 0030239633 scopus 로고    scopus 로고
    • IL-4-induced expression of the IL-1 receptor antagonist gene is mediated by STAT6
    • Ohmori Y., Smith M. F., Hamilton T. A. IL-4-induced expression of the IL-1 receptor antagonist gene is mediated by STAT6. J. Immunol. 1996; 157: 2058 – 2065
    • (1996) J. Immunol. , vol.157 , pp. 2058-2065
    • Ohmori, Y.1    Smith, M.F.2    Hamilton, T.A.3
  • 89
    • 0029876629 scopus 로고    scopus 로고
    • Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells
    • Kaplan M. H., Schindler U., Smiley S. T., Grusby M. J. Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells. Immunity 1996; 4: 313 – 319
    • (1996) Immunity , vol.4 , pp. 313-319
    • Kaplan, M.H.1    Schindler, U.2    Smiley, S.T.3    Grusby, M.J.4
  • 91
    • 0030587813 scopus 로고    scopus 로고
    • Impaired IL-13-mediated functions of macrophages in STAT6-deficient mice
    • Takeda K., Kamanaka M., Tanaka T., Kishimoto T., Akira S. Impaired IL-13-mediated functions of macrophages in STAT6-deficient mice. J. Immunol. 1996; 157: 3220 – 3222
    • (1996) J. Immunol. , vol.157 , pp. 3220-3222
    • Takeda, K.1    Kamanaka, M.2    Tanaka, T.3    Kishimoto, T.4    Akira, S.5
  • 93
    • 0029834119 scopus 로고    scopus 로고
    • Interleukin-4-specific signal transduction events are driven by homotypic interactions of the interleukin-4 receptor alpha subunit
    • Lai S. Y., Molden J., Liu K. D., Puck J. M., White M. D., Goldsmith M. A. Interleukin-4-specific signal transduction events are driven by homotypic interactions of the interleukin-4 receptor alpha subunit. EMBO J. 1996; 15: 4506 – 4514
    • (1996) EMBO J. , vol.15 , pp. 4506-4514
    • Lai, S.Y.1    Molden, J.2    Liu, K.D.3    Puck, J.M.4    White, M.D.5    Goldsmith, M.A.6
  • 94
    • 0030028353 scopus 로고    scopus 로고
    • Signal transduction pathway of interleukin-4 and interleukin-13 in human B cells derived from X-linked severe combined immunodeficiency patients
    • Izuhara K., Heike T., Otsuka T., Yamaoka K., Mayumi M., Imamura T., Niho Y., Harada N. Signal transduction pathway of interleukin-4 and interleukin-13 in human B cells derived from X-linked severe combined immunodeficiency patients. J. Biol. Chem. 1996; 271: 619 – 622
    • (1996) J. Biol. Chem. , vol.271 , pp. 619-622
    • Izuhara, K.1    Heike, T.2    Otsuka, T.3    Yamaoka, K.4    Mayumi, M.5    Imamura, T.6    Niho, Y.7    Harada, N.8
  • 95
    • 0027688778 scopus 로고
    • Requirement of tyrosine phosphorylation for rapid activation of a DNA binding factor by IL-4
    • Kotanides H., Reich N. C. Requirement of tyrosine phosphorylation for rapid activation of a DNA binding factor by IL-4. Science 1993; 262: 1265 – 1267
    • (1993) Science , vol.262 , pp. 1265-1267
    • Kotanides, H.1    Reich, N.C.2
  • 96
    • 0028341465 scopus 로고
    • Human interleukin-13 activates the interleukin-4-dependent transcription factor NF-IL-4 sharing a DNA binding motif with an interferon-gamma-induced nuclear binding factor
    • Kohler I., Alliger P., Minty A., Caput D., Ferrara P., Holl-Neugebauer B., Rank G., Rieber E. P. Human interleukin-13 activates the interleukin-4-dependent transcription factor NF-IL-4 sharing a DNA binding motif with an interferon-gamma-induced nuclear binding factor. FEBS. Lett. 1994; 345: 187 – 192
    • (1994) FEBS. Lett. , vol.345 , pp. 187-192
    • Kohler, I.1    Alliger, P.2    Minty, A.3    Caput, D.4    Ferrara, P.5    Holl-Neugebauer, B.6    Rank, G.7    Rieber, E.P.8
  • 97
    • 0028262965 scopus 로고
    • STF-IL-4: a novel IL-4-induced signal transducing factor
    • Schindler C., Kashleva H., Pernis A., Pine R., Rothman P. STF-IL-4: a novel IL-4-induced signal transducing factor. EMBO J. 1994; 13: 1350 – 1356
    • (1994) EMBO J. , vol.13 , pp. 1350-1356
    • Schindler, C.1    Kashleva, H.2    Pernis, A.3    Pine, R.4    Rothman, P.5
  • 98
    • 0028225367 scopus 로고
    • Interaction of the c-fes, proto-oncogene product with the interleukin-4 receptor
    • Izuhara K., Feldman R. A., Greer P., Harada N. Interaction of the c-fes, proto-oncogene product with the interleukin-4 receptor. J. Biol. Chem. 1994; 269: 18623 – 18629
    • (1994) J. Biol. Chem. , vol.269 , pp. 18623-18629
    • Izuhara, K.1    Feldman, R.A.2    Greer, P.3    Harada, N.4
  • 99
    • 0029849027 scopus 로고    scopus 로고
    • Interleukin-4 induces association of c-fes, proto-oncogene product with phosphatidylinositol-3 kinase
    • Izuhara K., Feldman R. A., Greer P., Harada N. Interleukin-4 induces association of c-fes, proto-oncogene product with phosphatidylinositol-3 kinase. Blood 1996; 88: 3910 – 3918
    • (1996) Blood , vol.88 , pp. 3910-3918
    • Izuhara, K.1    Feldman, R.A.2    Greer, P.3    Harada, N.4
  • 100
    • 0025237579 scopus 로고
    • Interleukin 4 activates human B lymphocytes via transient inositol lipid hydrolysis and delayed cyclic adenosine monophosphate generation
    • Finney M., Guy G. R., Michell R. H., Gordon J., Dugas B., Rigley K. P., Callard R. E. Interleukin 4 activates human B lymphocytes via transient inositol lipid hydrolysis and delayed cyclic adenosine monophosphate generation. Eur. J. Immunol. 1990; 20: 151 – 156
    • (1990) Eur. J. Immunol. , vol.20 , pp. 151-156
    • Finney, M.1    Guy, G.R.2    Michell, R.H.3    Gordon, J.4    Dugas, B.5    Rigley, K.P.6    Callard, R.E.7
  • 101
    • 0028923286 scopus 로고
    • Interleukin-13 inhibits protein kinase C-triggered respiratory burst in human monocytes. Role of calcium and cyclic AMP
    • Sozzani P., Cambon C., Vita N., Seguelas M. H., Caput D., Ferrara P., Pipy B. Interleukin-13 inhibits protein kinase C-triggered respiratory burst in human monocytes. Role of calcium and cyclic AMP. J. Biol. Chem. 1995; 270: 5084 – 5088
    • (1995) J. Biol. Chem. , vol.270 , pp. 5084-5088
    • Sozzani, P.1    Cambon, C.2    Vita, N.3    Seguelas, M.H.4    Caput, D.5    Ferrara, P.6    Pipy, B.7
  • 102
    • 0022975169 scopus 로고
    • BSF-1 induces membrane protein phosphorylation but not phosphoinositide metabolism, Ca2+ mobilization, protein kinase C translocation, or membrane depolarization in resting murine B lymphocytes
    • Justement L., Chen Z. Z., Harris L. K., Ransom J. T., Sandoval V. S., Smith C., Rennick D., Roehm N., Cambier J. BSF-1 induces membrane protein phosphorylation but not phosphoinositide metabolism, Ca2+ mobilization, protein kinase C translocation, or membrane depolarization in resting murine B lymphocytes. J. Immunol. 1986; 137: 3664 – 3670
    • (1986) J. Immunol. , vol.137 , pp. 3664-3670
    • Justement, L.1    Chen, Z.Z.2    Harris, L.K.3    Ransom, J.T.4    Sandoval, V.S.5    Smith, C.6    Rennick, D.7    Roehm, N.8    Cambier, J.9
  • 103
    • 0026777099 scopus 로고
    • IL-4 receptor signal transduction in human monocytes is associated with protein kinase C translocation
    • Arruda S., Ho J. L. IL-4 receptor signal transduction in human monocytes is associated with protein kinase C translocation. J. Immunol. 1992; 149: 1258 – 1264
    • (1992) J. Immunol. , vol.149 , pp. 1258-1264
    • Arruda, S.1    Ho, J.L.2
  • 104
    • 0028173717 scopus 로고
    • Interleukin-4-mediated inhibition of c-fos, mRNA expression: Role of the lipoxygenase directed pathway
    • Dokter W. H.A., Sierdsema S. J., Esselink M. T., Halie M. R., Vellenga E. Interleukin-4-mediated inhibition of c-fos, mRNA expression: Role of the lipoxygenase directed pathway. Leukemia 1994; 8: 1181 – 1184
    • (1994) Leukemia , vol.8 , pp. 1181-1184
    • Dokter, W.H.A.1    Sierdsema, S.J.2    Esselink, M.T.3    Halie, M.R.4    Vellenga, E.5
  • 105
    • 0024820636 scopus 로고
    • The effect of recombinant interleukin 4 upon protein kinase activities associated with murine and human B lymphocyte plasma membranes
    • McGarvie G. M., Cushley W. The effect of recombinant interleukin 4 upon protein kinase activities associated with murine and human B lymphocyte plasma membranes. Cell Signal 1989; 1: 447 – 460
    • (1989) Cell Signal , vol.1 , pp. 447-460
    • McGarvie, G.M.1    Cushley, W.2
  • 106
    • 0026000225 scopus 로고
    • Interleukin-4 proliferative signal transduction involves the activation of a tyrosine-specific phosphatase and the dephosphorylation of an 80-kDa protein
    • Mire-Sluis A. R., Thorpe R. Interleukin-4 proliferative signal transduction involves the activation of a tyrosine-specific phosphatase and the dephosphorylation of an 80-kDa protein. J. Biol. Chem. 1991; 266: 18113 – 18118
    • (1991) J. Biol. Chem. , vol.266 , pp. 18113-18118
    • Mire-Sluis, A.R.1    Thorpe, R.2
  • 107
    • 0030001762 scopus 로고    scopus 로고
    • Interleukin-13 is produced by activated human CD45RA+ and CD45RO+ T cells: modulation by interleukin-4 and interleukin-12
    • Jung T., Wijdenes J., Neumann C., de Vries J. E., Yssel H. Interleukin-13 is produced by activated human CD45RA+ and CD45RO+ T cells: modulation by interleukin-4 and interleukin-12. Eur. J. Immunol. 1996; 26: 571 – 577
    • (1996) Eur. J. Immunol. , vol.26 , pp. 571-577
    • Jung, T.1    Wijdenes, J.2    Neumann, C.3    de Vries, J.E.4    Yssel, H.5
  • 109
    • 0024353079 scopus 로고
    • Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties
    • Mosmann T. R., Coffman R. L. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Ann. Rev. Immunol. 1989; 7: 145 – 173
    • (1989) Ann. Rev. Immunol. , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coffman, R.L.2
  • 110
    • 0030024033 scopus 로고    scopus 로고
    • Human IL-13 production is negatively influenced by CD3 engagement. Enhancement of IL-13 production by cyclosporin A
    • Van Der Pouw Kraan T. C., Boeije L. C., Troon J. T., Rutschmann S. K., Wijdenes J., Aarden L. A. Human IL-13 production is negatively influenced by CD3 engagement. Enhancement of IL-13 production by cyclosporin A. J. Immunol. 1996; 156: 1818 – 1823
    • (1996) J. Immunol. , vol.156 , pp. 1818-1823
    • Van Der Pouw Kraan, T.C.1    Boeije, L.C.2    Troon, J.T.3    Rutschmann, S.K.4    Wijdenes, J.5    Aarden, L.A.6
  • 111
    • 0028085555 scopus 로고
    • CD30 defines a subset of activated human T cells that produce IFN-γ and IL-5 and exhibit enhanced B cell helper activity
    • Alzona M., Jäck H. M., Fisher R. I., Ellis T. M. CD30 defines a subset of activated human T cells that produce IFN-γ and IL-5 and exhibit enhanced B cell helper activity. J. Immunol. 1994; 153: 2861 – 2867
    • (1994) J. Immunol. , vol.153 , pp. 2861-2867
    • Alzona, M.1    Jäck, H.M.2    Fisher, R.I.3    Ellis, T.M.4
  • 112
    • 0028857640 scopus 로고
    • CD30, Th2 cytokines and HIV infection: a complex and fascinating link
    • Del Prete G., Maggi E., Pizzolo G., Romagnani S. CD30, Th2 cytokines and HIV infection: a complex and fascinating link. Immunol. Today 1995; 16: 76 – 80
    • (1995) Immunol. Today , vol.16 , pp. 76-80
    • Del Prete, G.1    Maggi, E.2    Pizzolo, G.3    Romagnani, S.4
  • 114
    • 0028835954 scopus 로고
    • High IL-4 production is a stable phenotype of CD8neg CD45R Aneg CD27neg T cells
    • Sunder-Plassmann R., Majdiç O., Knapp W., Holler W. High IL-4 production is a stable phenotype of CD8neg CD45R Aneg CD27neg T cells. Cell. Immunol. 1995; 160: 309 – 313
    • (1995) Cell. Immunol. , vol.160 , pp. 309-313
    • Sunder-Plassmann, R.1    Majdiç, O.2    Knapp, W.3    Holler, W.4
  • 115
    • 0028815671 scopus 로고
    • A ThO/Th2-like function of CD4+CD7- T helper cells from normal donors and HIV-infected patients
    • Autran B., Legac E., Blanc C., Debré P. A ThO/Th2-like function of CD4+CD7- T helper cells from normal donors and HIV-infected patients. J. Immunol. 1995; 154: 1408 – 1417
    • (1995) J. Immunol. , vol.154 , pp. 1408-1417
    • Autran, B.1    Legac, E.2    Blanc, C.3    Debré, P.4
  • 117
    • 8044250881 scopus 로고    scopus 로고
    • Regulation of the interleukin (IL)-12R /V2 subunit expression in developing T helper 1 (Th1) and Th2 cells
    • Szabo S. J., Dighe A. S., Gubler U., Murphy K. M. Regulation of the interleukin (IL)-12R /V2 subunit expression in developing T helper 1 (Th1) and Th2 cells. J. Exp. Med. 1997; 185: 817 – 824
    • (1997) J. Exp. Med. , vol.185 , pp. 817-824
    • Szabo, S.J.1    Dighe, A.S.2    Gubler, U.3    Murphy, K.M.4
  • 118
    • 0024357498 scopus 로고
    • Anti-proliferative effect of IFN-γ in immune regulation III. Differential selection of Th1 and Th2 murine helper T lymphocyte clones using recombinant IL-2 and recombinant IFN-γ
    • Gajewski T. F., Joyce J., Fitch F. W. Anti-proliferative effect of IFN-γ in immune regulation III. Differential selection of Th1 and Th2 murine helper T lymphocyte clones using recombinant IL-2 and recombinant IFN-γ. J. Immunol. 1989; 143: 15 – 22
    • (1989) J. Immunol. , vol.143 , pp. 15-22
    • Gajewski, T.F.1    Joyce, J.2    Fitch, F.W.3
  • 119
    • 0024342924 scopus 로고
    • Recombinant interleukin-4 suppresses the production of interferon γ by human mononuclear cells
    • Peleman R., Wu J., Fargeas C., Delespesse G. Recombinant interleukin-4 suppresses the production of interferon γ by human mononuclear cells. J. Exp. Med. 1989; 170: 1751 – 1756
    • (1989) J. Exp. Med. , vol.170 , pp. 1751-1756
    • Peleman, R.1    Wu, J.2    Fargeas, C.3    Delespesse, G.4
  • 120
    • 0025918157 scopus 로고
    • Role of cytokines in the differentiation of CD4+ T cell subsets in vivo
    • Coffman R. L., Varkila K., Scott P., Chatelain R. Role of cytokines in the differentiation of CD4+ T cell subsets in vivo. Immunol. Rev. 1991; 123: 189 – 207
    • (1991) Immunol. Rev. , vol.123 , pp. 189-207
    • Coffman, R.L.1    Varkila, K.2    Scott, P.3    Chatelain, R.4
  • 122
    • 0031048039 scopus 로고    scopus 로고
    • Multiple pathways for the initiation of T helper 2 (Th2) responses
    • Coffman R. L., von der Weid T. Multiple pathways for the initiation of T helper 2 (Th2) responses. J. Exp. Med. 1997; 185: 373 – 375
    • (1997) J. Exp. Med. , vol.185 , pp. 373-375
    • Coffman, R.L.1    von der Weid, T.2
  • 123
  • 126
    • 0028928646 scopus 로고
    • The functional role of CD8+ T helper type 2 cells
    • Seder R. A., Le Gros G. G. The functional role of CD8+ T helper type 2 cells. J. Exp. Med. 1995; 181: 5 – 7
    • (1995) J. Exp. Med. , vol.181 , pp. 5-7
    • Seder, R.A.1    Le Gros, G.G.2
  • 127
    • 0027164561 scopus 로고
    • Switch of CD8 T cells to noncytolytic CD8- CD4+ cells that make Th2 cytokines and help B cells
    • Erard F., Wild M. T., Garcia-Snaz J. A., Le Gros G. G. Switch of CD8 T cells to noncytolytic CD8- CD4+ cells that make Th2 cytokines and help B cells. Science 1993; 260: 1802 – 1805
    • (1993) Science , vol.260 , pp. 1802-1805
    • Erard, F.1    Wild, M.T.2    Garcia-Snaz, J.A.3    Le Gros, G.G.4
  • 128
    • 0028960040 scopus 로고
    • Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines
    • Sad S., Marcotte R., Mosmann T. R. Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines. Immunity 1995; 2: 271 – 279
    • (1995) Immunity , vol.2 , pp. 271-279
    • Sad, S.1    Marcotte, R.2    Mosmann, T.R.3
  • 131
    • 0027139766 scopus 로고
    • CD4+ type 1 and CD8+ type 2 T cell subsets in human leishmaniasis have distinct T cell receptor
    • Uyemura K., Pirmez C., Sieling P. A., Kiene K., Paes-Oliveira M., Modlin R. L. CD4+ type 1 and CD8+ type 2 T cell subsets in human leishmaniasis have distinct T cell receptor. J. Immunol. 1993; 151: 7095 – 7104
    • (1993) J. Immunol. , vol.151 , pp. 7095-7104
    • Uyemura, K.1    Pirmez, C.2    Sieling, P.A.3    Kiene, K.4    Paes-Oliveira, M.5    Modlin, R.L.6
  • 133
    • 0028177589 scopus 로고
    • CD4pos, NKl.lpos T cells promptly produce interleukin 4 in response to in vivo, challenge with anti-CD3
    • Yoshimoto T., Paul W. E. CD4pos, NKl.lpos T cells promptly produce interleukin 4 in response to in vivo, challenge with anti-CD3. J. Exp. Med. 1994; 179: 1285 – 1295
    • (1994) J. Exp. Med. , vol.179 , pp. 1285-1295
    • Yoshimoto, T.1    Paul, W.E.2
  • 135
    • 0027464843 scopus 로고
    • Human peripheral blood basophils primed by interleukin-3 (IL-3) produce IL-4 in response to immunoglobulin E receptor stimulation
    • Brunner T., Heusser C. H., Dahinden C. A. Human peripheral blood basophils primed by interleukin-3 (IL-3) produce IL-4 in response to immunoglobulin E receptor stimulation. J. Exp. Med. 1993; 177: 605 – 611
    • (1993) J. Exp. Med. , vol.177 , pp. 605-611
    • Brunner, T.1    Heusser, C.H.2    Dahinden, C.A.3
  • 136
    • 0029975243 scopus 로고    scopus 로고
    • IL-13 released by and localized in human basophils
    • Li H., Sim T. C., Alam R. IL-13 released by and localized in human basophils. J. Immunol. 1996; 156: 4833 – 4838
    • (1996) J. Immunol. , vol.156 , pp. 4833-4838
    • Li, H.1    Sim, T.C.2    Alam, R.3
  • 137
    • 0023667058 scopus 로고
    • B cell stimulatory factor-1/inter Ieukin-4 mRNA is expressed by normal and transformed mast cells
    • Brown M. A., Pierce J. H., Watson C. J., Falco J., Ihle J. N., Paul W. E. B cell stimulatory factor-1/inter Ieukin-4 mRNA is expressed by normal and transformed mast cells. Cell 1987; 50: 809 – 818
    • (1987) Cell , vol.50 , pp. 809-818
    • Brown, M.A.1    Pierce, J.H.2    Watson, C.J.3    Falco, J.4    Ihle, J.N.5    Paul, W.E.6
  • 138
  • 140
    • 0030999135 scopus 로고    scopus 로고
    • Nasal mast cells in perennial allergic rhinitics exhibit increased expression of the Fc epsilon Rl, CD40L, IL-4, and IL-13, and can induce IgE synthesis in B cells
    • Pawankar R., Okuda M., Yssel H., Okumura K., Ra C. Nasal mast cells in perennial allergic rhinitics exhibit increased expression of the Fc epsilon Rl, CD40L, IL-4, and IL-13, and can induce IgE synthesis in B cells. J. Clin. Invest. 1997; 99: 1492 – 1499
    • (1997) J. Clin. Invest. , vol.99 , pp. 1492-1499
    • Pawankar, R.1    Okuda, M.2    Yssel, H.3    Okumura, K.4    Ra, C.5
  • 142
    • 0029062988 scopus 로고
    • Interleukin-2 secretion by human B lymphocytes occurs as a late event and requires additional stimulation after CD40 cross-linking
    • Kindler V., Matthes T., Jeannin P., Zubler R. H. Interleukin-2 secretion by human B lymphocytes occurs as a late event and requires additional stimulation after CD40 cross-linking. Eur. J. Immunol. 1995; 25: 1239 – 1243
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1239-1243
    • Kindler, V.1    Matthes, T.2    Jeannin, P.3    Zubler, R.H.4
  • 146
    • 13344282080 scopus 로고    scopus 로고
    • Interleukin-13 inhibits interleukin-2-induced proliferation and protects chronic lymphocytic leukemia B cells from in vitro, apoptosis
    • Chaouchi N., Wallon C., Goujard C., Tertian G., Rudent A., Caput D., Ferrera P., Minty A., Vazquez A., Delfraissy J. F. Interleukin-13 inhibits interleukin-2-induced proliferation and protects chronic lymphocytic leukemia B cells from in vitro, apoptosis. Blood 1996; 87: 1022 – 1029
    • (1996) Blood , vol.87 , pp. 1022-1029
    • Chaouchi, N.1    Wallon, C.2    Goujard, C.3    Tertian, G.4    Rudent, A.5    Caput, D.6    Ferrera, P.7    Minty, A.8    Vazquez, A.9    Delfraissy, J.F.10
  • 147
    • 0024510874 scopus 로고
    • Increased expression of surface IgM but not IgD or IgG on human B cells in response to IL-4
    • Shields J. G., Armitage R., Jamieson B. N., Beverley P. C.L., Callard R. E. Increased expression of surface IgM but not IgD or IgG on human B cells in response to IL-4. Immunol. 1989; 66: 224 – 227
    • (1989) Immunol. , vol.66 , pp. 224-227
    • Shields, J.G.1    Armitage, R.2    Jamieson, B.N.3    Beverley, P.C.L.4    Callard, R.E.5
  • 148
    • 0025907438 scopus 로고
    • IL-4 and IL-2 upregulate the expression of antigen B7, the B cell counterstructure to T cell CD28: an amplification mechanism for T-B cell interactions
    • Vallé A., Aubry J. P., Durand I., Banchereau J. IL-4 and IL-2 upregulate the expression of antigen B7, the B cell counterstructure to T cell CD28: an amplification mechanism for T-B cell interactions. Int. Immunol. 1991; 3: 229 – 235
    • (1991) Int. Immunol. , vol.3 , pp. 229-235
    • Vallé, A.1    Aubry, J.P.2    Durand, I.3    Banchereau, J.4
  • 150
    • 0030056358 scopus 로고
    • CD40-CD40 ligand, a multifunctional receptor-ligand pair
    • Van Kooten C., Banchereau J. CD40-CD40 ligand, a multifunctional receptor-ligand pair. Adv. Immunol. 1995; 61: 1 – 77
    • (1995) Adv. Immunol. , vol.61 , pp. 1-77
    • Van Kooten, C.1    Banchereau, J.2
  • 151
    • 0024454176 scopus 로고
    • Interleukin 4 induces selective production of Interleukin 6 from normal human B lymphocytes
    • Smeland E. B., Blomhoff H. K., Funderud S., Shalaby M. R., Espevik T. Interleukin 4 induces selective production of Interleukin 6 from normal human B lymphocytes. J. Exp. Med. 1989; 170: 1463 – 1468
    • (1989) J. Exp. Med. , vol.170 , pp. 1463-1468
    • Smeland, E.B.1    Blomhoff, H.K.2    Funderud, S.3    Shalaby, M.R.4    Espevik, T.5
  • 153
    • 0027305427 scopus 로고
    • IL-13 induces proliferation and differentiation of human B cells activated by the CD40 ligand
    • Cocks B. C., de Waal Malefyt R., Galizzi J. P., de Vries J. E., Aversa G. IL-13 induces proliferation and differentiation of human B cells activated by the CD40 ligand. Int. Immunol. 1993; 5: 657 – 663
    • (1993) Int. Immunol. , vol.5 , pp. 657-663
    • Cocks, B.C.1    de Waal Malefyt, R.2    Galizzi, J.P.3    de Vries, J.E.4    Aversa, G.5
  • 154
    • 0026092621 scopus 로고
    • Long term human B cell lines dependent on interleukin 4 and antibody to CD40
    • Banchereau J., de Paoli P., Valle A., Garcia E., Rousset F. Long term human B cell lines dependent on interleukin 4 and antibody to CD40. Science 1991; 251: 70 – 72
    • (1991) Science , vol.251 , pp. 70-72
    • Banchereau, J.1    de Paoli, P.2    Valle, A.3    Garcia, E.4    Rousset, F.5
  • 155
    • 0023708633 scopus 로고
    • Interleukin 4 inhibits the proliferation but not the differentiation of activated human B cells in response to interleukin 2
    • Defrance T., Vanbervliet B., Aubry J. P., Banchereau J. Interleukin 4 inhibits the proliferation but not the differentiation of activated human B cells in response to interleukin 2. J. Exp. Med. 1988; 168: 1321 – 1337
    • (1988) J. Exp. Med. , vol.168 , pp. 1321-1337
    • Defrance, T.1    Vanbervliet, B.2    Aubry, J.P.3    Banchereau, J.4
  • 157
    • 0025170783 scopus 로고
    • IL-4 inhibits the expression of high affinity IL-2 receptors on monoclonal human B cells
    • Karray S., Dautry-Varsat A., Tsudo M., Merle-Beral H., Debré P., Galanaud P. IL-4 inhibits the expression of high affinity IL-2 receptors on monoclonal human B cells. J. Immunol. 1990; 145: 1152 – 1158
    • (1990) J. Immunol. , vol.145 , pp. 1152-1158
    • Karray, S.1    Dautry-Varsat, A.2    Tsudo, M.3    Merle-Beral, H.4    Debré, P.5    Galanaud, P.6
  • 158
    • 0028043897 scopus 로고
    • IL-13 has only a subset of IL-4 like activities on B chronic lymphocytic leukemia cells
    • Fluckiger A. C., Briere F., Zurawski G., Bridon J. M., Banchereau J. IL-13 has only a subset of IL-4 like activities on B chronic lymphocytic leukemia cells. Immunology 1994; 83: 397 – 403
    • (1994) Immunology , vol.83 , pp. 397-403
    • Fluckiger, A.C.1    Briere, F.2    Zurawski, G.3    Bridon, J.M.4    Banchereau, J.5
  • 159
    • 0022568935 scopus 로고
    • B cell stimulatory factor-1 enhances the lgE response of lipopolysaccharide-activated B cells
    • Coffman R. L., Ohara J., Bond M. W., Carty J., Zlotnick A., Paul W. E. B cell stimulatory factor-1 enhances the lgE response of lipopolysaccharide-activated B cells. J. Immunol. 1986; 136: 4538 – 4541
    • (1986) J. Immunol. , vol.136 , pp. 4538-4541
    • Coffman, R.L.1    Ohara, J.2    Bond, M.W.3    Carty, J.4    Zlotnick, A.5    Paul, W.E.6
  • 160
    • 0026026410 scopus 로고
    • Cytokine-induced proliferation and immunoglobulin production of human B lymphocytes triggered through their CD40 antigen
    • Rousset F., Garcia E., Banchereau J. Cytokine-induced proliferation and immunoglobulin production of human B lymphocytes triggered through their CD40 antigen. J. Exp. Med. 1991; 173: 705 – 710
    • (1991) J. Exp. Med. , vol.173 , pp. 705-710
    • Rousset, F.1    Garcia, E.2    Banchereau, J.3
  • 161
    • 0028829363 scopus 로고
    • IL-4 induces germ-line IgE heavy chain gene transcription in human fetal pre-B cells. Evidence for differential expression of functional IL-4 and IL-13 receptors during B cell ontogeny
    • Punnonen J., Cocks B. G., de Vries J. E. IL-4 induces germ-line IgE heavy chain gene transcription in human fetal pre-B cells. Evidence for differential expression of functional IL-4 and IL-13 receptors during B cell ontogeny. J. Immunol. 1995; 155: 4248 – 42254
    • (1995) J. Immunol. , vol.155 , pp. 4248-42254
    • Punnonen, J.1    Cocks, B.G.2    de Vries, J.E.3
  • 162
    • 0029741568 scopus 로고    scopus 로고
    • The human lgE germline promoter is regulated by interleukin-4, interleukin-13, interferon-alpha and interferon-gamma via an interferon-gamma-activated site and its flanking regions
    • Ezernieks J., Schnarr B., Metz K., Duschl A. The human lgE germline promoter is regulated by interleukin-4, interleukin-13, interferon-alpha and interferon-gamma via an interferon-gamma-activated site and its flanking regions. Eur. J. Biochem. 1996; 240: 667 – 673
    • (1996) Eur. J. Biochem. , vol.240 , pp. 667-673
    • Ezernieks, J.1    Schnarr, B.2    Metz, K.3    Duschl, A.4
  • 163
    • 0027381450 scopus 로고
    • Sequential switching from u to epsilon via gamma4 in human B cells stimulated with IL-4 and hydrocortisone
    • Jabara H. H., Loh R., Ramesh K., Vercelli D., Geha R. S. Sequential switching from u to epsilon via gamma4 in human B cells stimulated with IL-4 and hydrocortisone. J. Immunol. 1993; 151: 4528
    • (1993) J. Immunol. , vol.151 , pp. 4528
    • Jabara, H.H.1    Loh, R.2    Ramesh, K.3    Vercelli, D.4    Geha, R.S.5
  • 164
    • 0026532658 scopus 로고
    • Molecular analysis of the induction of immunoglobulin E synthesis in human B cells by interleukin 4 and engagement of CD40 antigen
    • Shapira S. K., Vercelli D., Jabara H. H., Fu S. M., Geha R. S. Molecular analysis of the induction of immunoglobulin E synthesis in human B cells by interleukin 4 and engagement of CD40 antigen. J. Exp. Med. 1992; 175: 289 – 292
    • (1992) J. Exp. Med. , vol.175 , pp. 289-292
    • Shapira, S.K.1    Vercelli, D.2    Jabara, H.H.3    Fu, S.M.4    Geha, R.S.5
  • 165
    • 0026036128 scopus 로고
    • Human B cell clones can be induced to proliferate and to switch to IgE and IgG4 synthesis by interleukin 4 and a signal provided by activated CD4+ T cell clones
    • Gascan H., Gauchat J. F., Roncarolo M. G., Yssel H., Spits H., de Vries J. E. Human B cell clones can be induced to proliferate and to switch to IgE and IgG4 synthesis by interleukin 4 and a signal provided by activated CD4+ T cell clones. J. Exp. Med. 1991; 173: 747 – 750
    • (1991) J. Exp. Med. , vol.173 , pp. 747-750
    • Gascan, H.1    Gauchat, J.F.2    Roncarolo, M.G.3    Yssel, H.4    Spits, H.5    de Vries, J.E.6
  • 166
    • 0026328818 scopus 로고
    • Generation and analysis of interleukin-4 deficient mice
    • Kühn R., Rajewsky K., Müller W. Generation and analysis of interleukin-4 deficient mice. Science 1991; 254: 707 – 710
    • (1991) Science , vol.254 , pp. 707-710
    • Kühn, R.1    Rajewsky, K.2    Müller, W.3
  • 167
    • 0025083185 scopus 로고
    • IL-4 induces allergic-like inflammatory disease and alters T cell development in transgenic mice
    • Tepper R. I., Levinson D. A., Stanger B. Z., Campos-Torres J., Abbas A. K., Leder P. IL-4 induces allergic-like inflammatory disease and alters T cell development in transgenic mice. Cell. 1990; 62: 457 – 467
    • (1990) Cell. , vol.62 , pp. 457-467
    • Tepper, R.I.1    Levinson, D.A.2    Stanger, B.Z.3    Campos-Torres, J.4    Abbas, A.K.5    Leder, P.6
  • 168
    • 0028860632 scopus 로고
    • IL-4 induces human B cell maturation and lgE synthesis in SCID-hu mice. Inhibition of ongoing IgE production by in vivo, treatment with an IL-4/IL-13 receptor antagonist
    • Carballido J. M., Schols D., Namikawa R., Zurawski S., Zurawski G., Roncarolo M. G., de Vries J. E. IL-4 induces human B cell maturation and lgE synthesis in SCID-hu mice. Inhibition of ongoing IgE production by in vivo, treatment with an IL-4/IL-13 receptor antagonist. J. Immunol. 1995; 155: 4162 – 4170
    • (1995) J. Immunol. , vol.155 , pp. 4162-4170
    • Carballido, J.M.1    Schols, D.2    Namikawa, R.3    Zurawski, S.4    Zurawski, G.5    Roncarolo, M.G.6    de Vries, J.E.7
  • 170
    • 0023133192 scopus 로고
    • B cell stimulatory factor 1/interleukin 4 is a potent costimulant for normal resting T lymphocytes
    • Hu-Li J., Shevach E. M., Mizuguchi J., Ohara J., Mosmann T., Paul W. E. B cell stimulatory factor 1/interleukin 4 is a potent costimulant for normal resting T lymphocytes. J. Exp. Med. 1987; 165: 157 – 172
    • (1987) J. Exp. Med. , vol.165 , pp. 157-172
    • Hu-Li, J.1    Shevach, E.M.2    Mizuguchi, J.3    Ohara, J.4    Mosmann, T.5    Paul, W.E.6
  • 171
    • 0024239620 scopus 로고
    • Specific inhibition of lymphokine biosynthesis and autocrine growth using antisense oligonucleotides in Th1 and Th2 helper T cell clones
    • Harel-Bellan A., Durum S., Muegge K., Abbas A. K., Farrar W. L. Specific inhibition of lymphokine biosynthesis and autocrine growth using antisense oligonucleotides in Th1 and Th2 helper T cell clones. J. Exp. Med. 1988; 168: 2309 – 2318
    • (1988) J. Exp. Med. , vol.168 , pp. 2309-2318
    • Harel-Bellan, A.1    Durum, S.2    Muegge, K.3    Abbas, A.K.4    Farrar, W.L.5
  • 172
    • 0025340811 scopus 로고
    • Inhibitory effect of IL-4 on the sepharose-CD3-induced proliferation of the CD4CD45RO human T cell subset
    • Gaya A., Alsinet E., Martorell J., Places L., De La Calle O., Yagüe J., Vives J. Inhibitory effect of IL-4 on the sepharose-CD3-induced proliferation of the CD4CD45RO human T cell subset. Int. Immunol. 1990; 2: 685 – 689
    • (1990) Int. Immunol. , vol.2 , pp. 685-689
    • Gaya, A.1    Alsinet, E.2    Martorell, J.3    Places, L.4    De La Calle, O.5    Yagüe, J.6    Vives, J.7
  • 173
    • 0023747688 scopus 로고
    • Interleukin-4 inhibits interleukin-2 mediated induction of human lymphokine activated killer cells, but not the generation of antigen specific cytotoxic T lymphocytes in mixed leucocyte cultures
    • Spits H., Yssel H., Paliard X., Kastelein R., Figdor D., de Vries J. E. Interleukin-4 inhibits interleukin-2 mediated induction of human lymphokine activated killer cells, but not the generation of antigen specific cytotoxic T lymphocytes in mixed leucocyte cultures. J. Immunol. 1988; 141: 29 – 36
    • (1988) J. Immunol. , vol.141 , pp. 29-36
    • Spits, H.1    Yssel, H.2    Paliard, X.3    Kastelein, R.4    Figdor, D.5    de Vries, J.E.6
  • 174
    • 0024237623 scopus 로고
    • IL-4 (B cell-stimulatory factor 1) regulates multiple aspects of influenza virus-specific cell-mediated immunity
    • Horohov D. W., Crim J. A., Smith P. L., Siegel J. P. IL-4 (B cell-stimulatory factor 1) regulates multiple aspects of influenza virus-specific cell-mediated immunity. J. Immunol. 1988; 141: 4217 – 4223
    • (1988) J. Immunol. , vol.141 , pp. 4217-4223
    • Horohov, D.W.1    Crim, J.A.2    Smith, P.L.3    Siegel, J.P.4
  • 175
    • 0024409831 scopus 로고
    • IL-4 regulates IL-2 induction of lymphokine-activated killer activity from human lymphocytes
    • Kawakami Y., Custer M. C., Rosenberg S. A., Lotze M. T. IL-4 regulates IL-2 induction of lymphokine-activated killer activity from human lymphocytes. J. Immunol. 1989; 142: 3452 – 3461
    • (1989) J. Immunol. , vol.142 , pp. 3452-3461
    • Kawakami, Y.1    Custer, M.C.2    Rosenberg, S.A.3    Lotze, M.T.4
  • 176
    • 0029067565 scopus 로고
    • Production of IL-5 by human NK cells and regulation of IL-5 secretion by IL-4, IL-10, and IL-12
    • Warren H. S., Kinnear B. F., Phillips J. H., Lanier L. L. Production of IL-5 by human NK cells and regulation of IL-5 secretion by IL-4, IL-10, and IL-12. J. Immunol. 1995; 154: 5144 – 5152
    • (1995) J. Immunol. , vol.154 , pp. 5144-5152
    • Warren, H.S.1    Kinnear, B.F.2    Phillips, J.H.3    Lanier, L.L.4
  • 178
    • 0027183125 scopus 로고
    • Interleukin-4 and its receptor; Modulating effects on immature and mature hematopoietic cells
    • Vellenga E., Dokter W., Halie R. M. Interleukin-4 and its receptor; Modulating effects on immature and mature hematopoietic cells. Leukemia 1993; 7: 1131 – 1141
    • (1993) Leukemia , vol.7 , pp. 1131-1141
    • Vellenga, E.1    Dokter, W.2    Halie, R.M.3
  • 179
    • 0027404227 scopus 로고
    • Human interleukin-4 inhibits proliferation of megakaryocyte progenitor cells in culture
    • Sonoda Y., Kuzuyama Y., Tanaka S., Yokota S., Maekawa T., Clark S. C., Abe T. Human interleukin-4 inhibits proliferation of megakaryocyte progenitor cells in culture. Blood 1993; 81: 624 – 630
    • (1993) Blood , vol.81 , pp. 624-630
    • Sonoda, Y.1    Kuzuyama, Y.2    Tanaka, S.3    Yokota, S.4    Maekawa, T.5    Clark, S.C.6    Abe, T.7
  • 180
    • 0029164555 scopus 로고
    • Differential effects of recombinant human interleukin-13 on the in vitro, growth of human haemopoietic progenitor cells
    • Xi X., Schlegel N., Caen J. P., Minty A., Fournier S., Caput D., Ferrera P., Han Z. C. Differential effects of recombinant human interleukin-13 on the in vitro, growth of human haemopoietic progenitor cells. Br. J. Haematol. 1995; 90: 921 – 927
    • (1995) Br. J. Haematol. , vol.90 , pp. 921-927
    • Xi, X.1    Schlegel, N.2    Caen, J.P.3    Minty, A.4    Fournier, S.5    Caput, D.6    Ferrera, P.7    Han, Z.C.8
  • 181
    • 1842340840 scopus 로고    scopus 로고
    • Continuous administration of IL-13 to mice induces extramedullary hemopoiesis and monocytosis
    • Lai Y. H., Heslan J. M., Poppema S., Elliot J. F., Mosmann T. R. Continuous administration of IL-13 to mice induces extramedullary hemopoiesis and monocytosis. J. Immunol. 1996; 156: 3166 – 3173
    • (1996) J. Immunol. , vol.156 , pp. 3166-3173
    • Lai, Y.H.1    Heslan, J.M.2    Poppema, S.3    Elliot, J.F.4    Mosmann, T.R.5
  • 182
    • 0029010501 scopus 로고
    • Interleukin-13 selectively suppresses the growth of human macrophage progenitors at the late stage
    • Sakamoto O., Hashiyama M., Minty A., Ando M., Suda T. Interleukin-13 selectively suppresses the growth of human macrophage progenitors at the late stage. Blood 1995; 85: 3487 – 3493
    • (1995) Blood , vol.85 , pp. 3487-3493
    • Sakamoto, O.1    Hashiyama, M.2    Minty, A.3    Ando, M.4    Suda, T.5
  • 183
    • 0028303167 scopus 로고
    • Interleukin-13: novel role in direct regulation of proliferation and differentiation of primitive hematopoietic progenitor cells
    • Jacobsen S. E., Okkenhaug C., Veiby O. P., Caput D., Ferrara P., Minty A. Interleukin-13: novel role in direct regulation of proliferation and differentiation of primitive hematopoietic progenitor cells. J. Exp. Med. 1994; 180: 75 – 82
    • (1994) J. Exp. Med. , vol.180 , pp. 75-82
    • Jacobsen, S.E.1    Okkenhaug, C.2    Veiby, O.P.3    Caput, D.4    Ferrara, P.5    Minty, A.6
  • 184
    • 0027492915 scopus 로고
    • Effects of IL-13 on pheno-type, cytokine production, and cytotoxic function of human monocytes. Comparison with IL-4 and modulation by 1FNγ or IL-10
    • de Waal Malefyt R., Figdor C., Huijbens R., Mohan-Peterson S., Bennett B., Culpepper J., Dang W., Zurawski G., de Vries J. E. Effects of IL-13 on pheno-type, cytokine production, and cytotoxic function of human monocytes. Comparison with IL-4 and modulation by 1FNγ or IL-10. J. Immunol. 1993; 151: 6370 – 6381
    • (1993) J. Immunol. , vol.151 , pp. 6370-6381
    • de Waal Malefyt, R.1    Figdor, C.2    Huijbens, R.3    Mohan-Peterson, S.4    Bennett, B.5    Culpepper, J.6    Dang, W.7    Zurawski, G.8    de Vries, J.E.9
  • 185
    • 0025361670 scopus 로고
    • IL-4 induced expression of Fc, RIIb and soluble Fc, RIIb release from human monocytes is downregulated by IFNα and IFNγ
    • Te Velde A. A., Rousset F., Péronne C., de Vries J. E., Figdor C. IL-4 induced expression of Fc, RIIb and soluble Fc, RIIb release from human monocytes is downregulated by IFNα and IFNγ. J. Immunol. 1990; 144: 3052 – 3059
    • (1990) J. Immunol. , vol.144 , pp. 3052-3059
    • Te Velde, A.A.1    Rousset, F.2    Péronne, C.3    de Vries, J.E.4    Figdor, C.5
  • 187
    • 0028289244 scopus 로고
    • Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha
    • Sallusto F., Lanzavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J. Exp. Med. 1994; 179: 1109 – 1118
    • (1994) J. Exp. Med. , vol.179 , pp. 1109-1118
    • Sallusto, F.1    Lanzavecchia, A.2
  • 189
    • 0029961746 scopus 로고    scopus 로고
    • CD 14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells
    • Zhou L. J., Tedder T. F. CD 14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells. Proc. Natl. Acad. Sci. USA 1996; 93: 2588 – 2592
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 2588-2592
    • Zhou, L.J.1    Tedder, T.F.2
  • 190
    • 0030293442 scopus 로고    scopus 로고
    • Molecular and functional characteristics of dendritic cells generated from highly purified CD14+ peripheral blood monocytes
    • Pickl W. F., Majdic O., Kohl P., Stockl J., Riedl E., Scheinecker C., Bello-Fernandez C., Knapp W. Molecular and functional characteristics of dendritic cells generated from highly purified CD14+ peripheral blood monocytes. J. Immunol. 1996; 157: 3850 – 3859
    • (1996) J. Immunol. , vol.157 , pp. 3850-3859
    • Pickl, W.F.1    Majdic, O.2    Kohl, P.3    Stockl, J.4    Riedl, E.5    Scheinecker, C.6    Bello-Fernandez, C.7    Knapp, W.8
  • 191
    • 0031110968 scopus 로고    scopus 로고
    • Interleukin-13 induces human monocyte/macrophage fusion and macrophage mannose receptor expression
    • Defife K. M., Jenney C. R., McNally A. K., Colton E., Anderson J. M. Interleukin-13 induces human monocyte/macrophage fusion and macrophage mannose receptor expression. J. Immunol. 1997; 158: 3385 – 3390
    • (1997) J. Immunol. , vol.158 , pp. 3385-3390
    • Defife, K.M.1    Jenney, C.R.2    McNally, A.K.3    Colton, E.4    Anderson, J.M.5
  • 192
    • 0000999931 scopus 로고
    • Potential anti-inflammatory effects of interleukin 4: suppression of human monocyte tumor necrosis factor α, interleukin 1, and prostaglandin E2
    • Hart P. H., Vitti G. F., Burgess D. R., Whitty G. A., Piccoli D. S., Hamilton J. A. Potential anti-inflammatory effects of interleukin 4: suppression of human monocyte tumor necrosis factor α, interleukin 1, and prostaglandin E2. Proc. Natl. Acad. Sci. USA 1989; 86: 3803 – 3807
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 3803-3807
    • Hart, P.H.1    Vitti, G.F.2    Burgess, D.R.3    Whitty, G.A.4    Piccoli, D.S.5    Hamilton, J.A.6
  • 193
    • 0028911482 scopus 로고
    • Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the production of cytokines by human peripheral blood mononuclear cells: priming for IL-12 and tumor necrosis factor alpha production
    • D'Andrea A., Ma X., Aste-Amezaga M., Paganin C., Trinchieri G. Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the production of cytokines by human peripheral blood mononuclear cells: priming for IL-12 and tumor necrosis factor alpha production. J. Exp. Med. 1995; 181: 537 – 546
    • (1995) J. Exp. Med. , vol.181 , pp. 537-546
    • D'Andrea, A.1    Ma, X.2    Aste-Amezaga, M.3    Paganin, C.4    Trinchieri, G.5
  • 194
    • 15844404868 scopus 로고    scopus 로고
    • Interleukin-13 (IL-13) induces IL-1 receptor antagonist gene expression and protein synthesis in peripheral blood mononuclear cells: inhibition by an IL-4 mutant protein
    • Vannier E., de Waal Malefyt R., Salazar-Montes A., de Vries J. E., Dinarello C. A. Interleukin-13 (IL-13) induces IL-1 receptor antagonist gene expression and protein synthesis in peripheral blood mononuclear cells: inhibition by an IL-4 mutant protein. Blood 1996; 87: 3307 – 3315
    • (1996) Blood , vol.87 , pp. 3307-3315
    • Vannier, E.1    de Waal Malefyt, R.2    Salazar-Montes, A.3    de Vries, J.E.4    Dinarello, C.A.5
  • 195
    • 0030578447 scopus 로고    scopus 로고
    • IL-4 and IL-13 modulate IL-10 release in endotoxin-stimulated murine peritoneal mononuclear phagocytes
    • Kambayashi T., Jacob C. O., Strassmann G. IL-4 and IL-13 modulate IL-10 release in endotoxin-stimulated murine peritoneal mononuclear phagocytes. Cell. Immunol. 1996; 171: 153 – 158
    • (1996) Cell. Immunol. , vol.171 , pp. 153-158
    • Kambayashi, T.1    Jacob, C.O.2    Strassmann, G.3
  • 197
    • 0026515544 scopus 로고
    • Interleukin 4 inhibition of prostaglandin E2 synthesis blocks interstitial collagenase and 92-kDa type IV collagenase/gelatinase production by human monocytes
    • Corcoran M. L., Stetler-Stevenson W. G., Brown P. D., Wahl L. M. Interleukin 4 inhibition of prostaglandin E2 synthesis blocks interstitial collagenase and 92-kDa type IV collagenase/gelatinase production by human monocytes. J. Biol. Chem. 1992; 267: 515 – 519
    • (1992) J. Biol. Chem. , vol.267 , pp. 515-519
    • Corcoran, M.L.1    Stetler-Stevenson, W.G.2    Brown, P.D.3    Wahl, L.M.4
  • 198
    • 0025099266 scopus 로고
    • IL-4 inhibits superoxide production by human mononuclear phagocytes
    • Abramson S. L., Gallin J. I. IL-4 inhibits superoxide production by human mononuclear phagocytes. J. Immunol. 1990; 144: 625 – 63
    • (1990) J. Immunol. , vol.144 , pp. 625-663
    • Abramson, S.L.1    Gallin, J.I.2
  • 199
    • 0029871319 scopus 로고    scopus 로고
    • LPS-dependent cyclooxygenase-2 induction in human monocytes is down-regulated by IL-13, but not by IFN-gamma
    • Endo T., Ogushi F., Sone S. LPS-dependent cyclooxygenase-2 induction in human monocytes is down-regulated by IL-13, but not by IFN-gamma. J. Immunol. 1996; 156: 2240 – 2246
    • (1996) J. Immunol. , vol.156 , pp. 2240-2246
    • Endo, T.1    Ogushi, F.2    Sone, S.3
  • 200
    • 0028859171 scopus 로고
    • Differential effects of anti-inflammatory cytokines (IL-4, IL-10 and IL-13) on tumoricidal and chemotactic properties of human monocytes induced by monocyte chemoractic and activating factor
    • Yano S., Sone S., Nishioka Y., Mukaida N., Matsushima K., Ogura T. Differential effects of anti-inflammatory cytokines (IL-4, IL-10 and IL-13) on tumoricidal and chemotactic properties of human monocytes induced by monocyte chemoractic and activating factor. J. Leukoc. Biol. 1995; 57: 303 – 309
    • (1995) J. Leukoc. Biol. , vol.57 , pp. 303-309
    • Yano, S.1    Sone, S.2    Nishioka, Y.3    Mukaida, N.4    Matsushima, K.5    Ogura, T.6
  • 201
    • 0030639030 scopus 로고    scopus 로고
    • Pathways for the regulation of macrophage iron metabolism by the anti-inflammatory cytokines IL-4 and IL-13
    • Weiss G., Bodgan C., Hentze M. W. Pathways for the regulation of macrophage iron metabolism by the anti-inflammatory cytokines IL-4 and IL-13. J. Immunol. 1997; 158: 420 – 425
    • (1997) J. Immunol. , vol.158 , pp. 420-425
    • Weiss, G.1    Bodgan, C.2    Hentze, M.W.3
  • 202
    • 0027934352 scopus 로고
    • Mechanisms of IL-4-mediated suppression of IP-gene expression in murine macrophages
    • Deng W., Ohmori Y., Hamilton T. A. Mechanisms of IL-4-mediated suppression of IP-gene expression in murine macrophages. J. Immunol. 1994; 153: 2130 – 2136
    • (1994) J. Immunol. , vol.153 , pp. 2130-2136
    • Deng, W.1    Ohmori, Y.2    Hamilton, T.A.3
  • 205
    • 0031569104 scopus 로고    scopus 로고
    • IL-13 protects mice from lipopolysaccharide-induced lethal endotoxemia
    • Muchamuel T., Menon S., Pisacane P., Howard M. C., Cockayne D. A. IL-13 protects mice from lipopolysaccharide-induced lethal endotoxemia. J. Immunol. 1997; 158: 2898 – 2903
    • (1997) J. Immunol. , vol.158 , pp. 2898-2903
    • Muchamuel, T.1    Menon, S.2    Pisacane, P.3    Howard, M.C.4    Cockayne, D.A.5
  • 206
    • 0029078353 scopus 로고
    • Stimulation of the expression and the enzyme activity of aminopeptidase N/CD13 and dipeptidylpeptidase IV/CD26 on human renal cell carcinoma cells and renal tubular epithelial cells by T cell-derived cytokines, such as IL-4 and IL-13
    • Riemann D., Kehlen A., Langner J. Stimulation of the expression and the enzyme activity of aminopeptidase N/CD13 and dipeptidylpeptidase IV/CD26 on human renal cell carcinoma cells and renal tubular epithelial cells by T cell-derived cytokines, such as IL-4 and IL-13. Clin. Exp. Immunol. 1995; 100: 277 – 283
    • (1995) Clin. Exp. Immunol. , vol.100 , pp. 277-283
    • Riemann, D.1    Kehlen, A.2    Langner, J.3
  • 207
    • 0028041265 scopus 로고
    • Potential indirect antiinflammatory effects of IL-4. Stimulation of human monocytes, macrophages, and endothelial cells by IL-4 increases aminopeptidase-N activity (CD13; EC 3.4.11.2)
    • Van Hal P. T.W., Hopstaken-Broos J. P.M., Prins A., Favaloro E. J., Huijbens R. J.F., Hilvering C., Figdor C. G., Hoogsteden H. C. Potential indirect antiinflammatory effects of IL-4. Stimulation of human monocytes, macrophages, and endothelial cells by IL-4 increases aminopeptidase-N activity (CD13; EC 3.4.11.2). J. Immunol. 1994; 153: 2718 – 2728
    • (1994) J. Immunol. , vol.153 , pp. 2718-2728
    • Van Hal, P.T.W.1    Hopstaken-Broos, J.P.M.2    Prins, A.3    Favaloro, E.J.4    Huijbens, R.J.F.5    Hilvering, C.6    Figdor, C.G.7    Hoogsteden, H.C.8
  • 208
    • 0028127310 scopus 로고
    • Induction of 15-lipoxygenase by interleukin-13 in human blood monocytes
    • Nassar G. M., Morrow J. D., Roberts L. J., Lakkis F. G., Badr K. F. Induction of 15-lipoxygenase by interleukin-13 in human blood monocytes. J. Biol. Chem. 1994; 269: 27631 – 27634
    • (1994) J. Biol. Chem. , vol.269 , pp. 27631-27634
    • Nassar, G.M.1    Morrow, J.D.2    Roberts, L.J.3    Lakkis, F.G.4    Badr, K.F.5
  • 209
    • 0024460107 scopus 로고
    • IL-4 inhibits H2O2 production and antileishmanial capacity of human cultured monocytes mediated by IFN-γ
    • Lehn M., Weiser W. Y., Engelhorn S., Gillis S., Remold H. G. IL-4 inhibits H2O2 production and antileishmanial capacity of human cultured monocytes mediated by IFN-γ. J. Immunol. 1989; 143: 3020 – 3024
    • (1989) J. Immunol. , vol.143 , pp. 3020-3024
    • Lehn, M.1    Weiser, W.Y.2    Engelhorn, S.3    Gillis, S.4    Remold, H.G.5
  • 210
    • 0026751012 scopus 로고
    • IL-4 inhibits macrophage-mediated killing of Plasmodium Falciparum in vitro
    • Kumaratilake L. M., Ferrante A. IL-4 inhibits macrophage-mediated killing of Plasmodium Falciparum in vitro. J. Immunol. 1992; 149: 194 – 199
    • (1992) J. Immunol. , vol.149 , pp. 194-199
    • Kumaratilake, L.M.1    Ferrante, A.2
  • 213
    • 0025265090 scopus 로고
    • Inhibition of IgG-triggered human eosinophil function by IL-4
    • Baskar P., Silberstein D. S., Pincus S. H. Inhibition of IgG-triggered human eosinophil function by IL-4. J. Immunol. 1990; 144: 2321 – 2326
    • (1990) J. Immunol. , vol.144 , pp. 2321-2326
    • Baskar, P.1    Silberstein, D.S.2    Pincus, S.H.3
  • 214
    • 0030586671 scopus 로고    scopus 로고
    • Activation of human eosinophils by IL-13. Induction of CD69 surface antigen, its relationship to messenger RNA expression, and promotion of cellular viability
    • Luttmann W., Knoechel B., Foerster M., Matthys H., Virchow J. C., Kroegel C. Activation of human eosinophils by IL-13. Induction of CD69 surface antigen, its relationship to messenger RNA expression, and promotion of cellular viability. J. Immunol. 1996; 157: 1678 – 1683
    • (1996) J. Immunol. , vol.157 , pp. 1678-1683
    • Luttmann, W.1    Knoechel, B.2    Foerster, M.3    Matthys, H.4    Virchow, J.C.5    Kroegel, C.6
  • 215
  • 219
    • 0028287509 scopus 로고
    • Interleukin-13 induces expression and release of interleukin-1 decoy receptor in human polymorphonuclear cells
    • Colotta F., Re F., Muzio M., Polentarutti N., Minty A., Caput D., Ferrara P., Mantovani A. Interleukin-13 induces expression and release of interleukin-1 decoy receptor in human polymorphonuclear cells. J. Biol Chem. 1994; 269: 12403 – 12406
    • (1994) J. Biol Chem. , vol.269 , pp. 12403-12406
    • Colotta, F.1    Re, F.2    Muzio, M.3    Polentarutti, N.4    Minty, A.5    Caput, D.6    Ferrara, P.7    Mantovani, A.8
  • 220
    • 0028922191 scopus 로고
    • Effects of interleukin (IL)-13 on immediate-early response gene expression, phenotype and differentiation of human mast cells. Comparison with IL-4
    • Nilsson G., Nilsson K. Effects of interleukin (IL)-13 on immediate-early response gene expression, phenotype and differentiation of human mast cells. Comparison with IL-4. Eur. J. Immunol. 1995; 25: 870 – 873
    • (1995) Eur. J. Immunol. , vol.25 , pp. 870-873
    • Nilsson, G.1    Nilsson, K.2
  • 221
    • 0025998184 scopus 로고
    • Fibroblast chemotaxis induction by human recombinant interleukin-4. Identification by synthetic peptide analysis of two chemotactic domains residing in amino acid sequences 70–88 and 89–122
    • Postlethwaite A. E., Seyer J. M. Fibroblast chemotaxis induction by human recombinant interleukin-4. Identification by synthetic peptide analysis of two chemotactic domains residing in amino acid sequences 70–88 and 89–122. J. Clin. Invest. 1991; 87: 2147 – 2152
    • (1991) J. Clin. Invest. , vol.87 , pp. 2147-2152
    • Postlethwaite, A.E.1    Seyer, J.M.2
  • 223
    • 0026446005 scopus 로고
    • Human fibroblasts synthetize elevated levels of extracellular matrix proteins in response to interleukin 4
    • Postlethwaite A. E., Holness M. A., Katai H., Raghow R. Human fibroblasts synthetize elevated levels of extracellular matrix proteins in response to interleukin 4. J. Clin. Invest. 1992; 90: 1479 – 1485
    • (1992) J. Clin. Invest. , vol.90 , pp. 1479-1485
    • Postlethwaite, A.E.1    Holness, M.A.2    Katai, H.3    Raghow, R.4
  • 224
    • 0029003842 scopus 로고
    • Stimulation of sulphated glycosaminoglycan and decorin production in adult dermal fibroblasts by recombinant human interleukin-4
    • Wegrowski Y., Paltot V., Gillery P., Kalis B., Randoux A., Maquart F. X. Stimulation of sulphated glycosaminoglycan and decorin production in adult dermal fibroblasts by recombinant human interleukin-4. Biochem. J. 1995; 307: 673 – 678
    • (1995) Biochem. J. , vol.307 , pp. 673-678
    • Wegrowski, Y.1    Paltot, V.2    Gillery, P.3    Kalis, B.4    Randoux, A.5    Maquart, F.X.6
  • 225
    • 0029075931 scopus 로고
    • IL-13 results in differential regulation of the complement proteins C3 and factor B in tumor necrosis factor (TNF)-stimulated fibroblasts
    • Katz Y., Stav D., Barr J., Passwell J. H. IL-13 results in differential regulation of the complement proteins C3 and factor B in tumor necrosis factor (TNF)-stimulated fibroblasts. Clin. Exp. Immunol. 1995; 101: 150 – 156
    • (1995) Clin. Exp. Immunol. , vol.101 , pp. 150-156
    • Katz, Y.1    Stav, D.2    Barr, J.3    Passwell, J.H.4
  • 226
    • 0027431910 scopus 로고
    • Interleukin 4 inhibits growth factor-stimulated rheumatoid synoviocyte proliferation by blocking the early phases of the cell cycle
    • Dechanet J., Briolay J., Rissoan M. C., Chomarat P., Galizzi J. P., Banchereau J., Miossec P. Interleukin 4 inhibits growth factor-stimulated rheumatoid synoviocyte proliferation by blocking the early phases of the cell cycle. J. Immunol. 1993; 151: 4908 – 4917
    • (1993) J. Immunol. , vol.151 , pp. 4908-4917
    • Dechanet, J.1    Briolay, J.2    Rissoan, M.C.3    Chomarat, P.4    Galizzi, J.P.5    Banchereau, J.6    Miossec, P.7
  • 227
    • 0028605693 scopus 로고
    • Interleukin-4 but not interleukin-10 inhibits the production of leukemia inhibitory factor by rheumatoid synovium and synoviocytes
    • Dechanet J., Taupin J. L., Chomarat P., Rissoan M. C., Moreau J. F., Banchereau J., Miossec P. Interleukin-4 but not interleukin-10 inhibits the production of leukemia inhibitory factor by rheumatoid synovium and synoviocytes. Eur. J. Immunol. 1994; 24: 3222 – 3228
    • (1994) Eur. J. Immunol. , vol.24 , pp. 3222-3228
    • Dechanet, J.1    Taupin, J.L.2    Chomarat, P.3    Rissoan, M.C.4    Moreau, J.F.5    Banchereau, J.6    Miossec, P.7
  • 228
    • 0029027422 scopus 로고
    • Effects of Th1 and Th2 cytokines on cytokine production and 1CAM-1 expression on synovial fibroblasts
    • Schlaak J. F., Schwarting A., Knolle P., Meyer zum Buschenfelde K. H., Mayet W. Effects of Th1 and Th2 cytokines on cytokine production and 1CAM-1 expression on synovial fibroblasts. Ann. Rheum. Dis. 1995; 54: 560 – 565
    • (1995) Ann. Rheum. Dis. , vol.54 , pp. 560-565
    • Schlaak, J.F.1    Schwarting, A.2    Knolle, P.3    Meyer zum Buschenfelde, K.H.4    Mayet, W.5
  • 229
    • 0025755792 scopus 로고
    • Interleukin 4 alone or in combination with interleukin 1 stimulates 3T3 fibroblasts to produce colony-stimulating factors
    • Tushinski R. J., Larsen A., Park L. S., Spoor E. Interleukin 4 alone or in combination with interleukin 1 stimulates 3T3 fibroblasts to produce colony-stimulating factors. Exp. Hematol. 1991; 19: 238 – 244
    • (1991) Exp. Hematol. , vol.19 , pp. 238-244
    • Tushinski, R.J.1    Larsen, A.2    Park, L.S.3    Spoor, E.4
  • 230
    • 0029836785 scopus 로고    scopus 로고
    • Opposite effects of interleukin-13 and interleukin-12 on the release of inflammatory cytokines, cytokine inhibitors and prostaglandin E from synovial fibroblasts and blood mononuclear cells
    • Seitz M., Loetscher P., Dewald B., Towbin H., Baggiolini M. Opposite effects of interleukin-13 and interleukin-12 on the release of inflammatory cytokines, cytokine inhibitors and prostaglandin E from synovial fibroblasts and blood mononuclear cells. Eur. J. Immunol. 1996; 26: 2198 – 2202
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2198-2202
    • Seitz, M.1    Loetscher, P.2    Dewald, B.3    Towbin, H.4    Baggiolini, M.5
  • 231
    • 0026501594 scopus 로고
    • Regulation of ICAM-1 expression and function in human dermal fibroblasts by IL-4
    • Piela-Smith T. H., Broketa G., Hand A., Korn J. H. Regulation of ICAM-1 expression and function in human dermal fibroblasts by IL-4. J. Immunol. 1992; 148: 1375 – 1381
    • (1992) J. Immunol. , vol.148 , pp. 1375-1381
    • Piela-Smith, T.H.1    Broketa, G.2    Hand, A.3    Korn, J.H.4
  • 232
    • 0026558355 scopus 로고
    • Inhibition of colon and breast carcinoma cell growth by Interleukin-4
    • Toi M., Bicknell R., Harris A. L. Inhibition of colon and breast carcinoma cell growth by Interleukin-4. Cancer Res. 1992; 52: 275 – 279
    • (1992) Cancer Res. , vol.52 , pp. 275-279
    • Toi, M.1    Bicknell, R.2    Harris, A.L.3
  • 233
    • 0026073847 scopus 로고
    • Tumor necrosis factor combines with IL-4 or IFN-γ to selectively enhance endothelial cell adhesiveness for T cells. The contribution of vascular cell adhesion molecule-1-dependent and-independent binding mechanisms
    • Thornhill M. H., Wellicome S. M., Mahiouz D. L., Lanchbury J. S.S., Kyan-Aung U., Haskard D. O. Tumor necrosis factor combines with IL-4 or IFN-γ to selectively enhance endothelial cell adhesiveness for T cells. The contribution of vascular cell adhesion molecule-1-dependent and-independent binding mechanisms. J. Immunol. 1991; 146: 592 – 598
    • (1991) J. Immunol. , vol.146 , pp. 592-598
    • Thornhill, M.H.1    Wellicome, S.M.2    Mahiouz, D.L.3    Lanchbury, J.S.S.4    Kyan-Aung, U.5    Haskard, D.O.6
  • 234
    • 0028986026 scopus 로고
    • IL-4 induction of VCAM-1 on endothelial cells involves activation of a protein tyrosine kinase
    • Palmer-Crocker R. L., Pober J. S. IL-4 induction of VCAM-1 on endothelial cells involves activation of a protein tyrosine kinase. J. Immunol. 1995; 154: 2838 – 2845
    • (1995) J. Immunol. , vol.154 , pp. 2838-2845
    • Palmer-Crocker, R.L.1    Pober, J.S.2
  • 235
    • 15444341552 scopus 로고    scopus 로고
    • Tumor necrosis factor α enhances the expression of the interleukin (IL)-4 receptor α-chain on endothelial cells increasing IL-4 or IL-13-induced Stat6 activation
    • Lugli S. M., Feng N., Heim M. H., Adam M., Schnyder B., Etter H., Yamage M., Eugster H. P., Lutz R. A., Zurawski G., Moser R. Tumor necrosis factor α enhances the expression of the interleukin (IL)-4 receptor α-chain on endothelial cells increasing IL-4 or IL-13-induced Stat6 activation. J. Biol Chem. 1997; 272: 5487 – 5494
    • (1997) J. Biol Chem. , vol.272 , pp. 5487-5494
    • Lugli, S.M.1    Feng, N.2    Heim, M.H.3    Adam, M.4    Schnyder, B.5    Etter, H.6    Yamage, M.7    Eugster, H.P.8    Lutz, R.A.9    Zurawski, G.10    Moser, R.11
  • 236
    • 0026692094 scopus 로고
    • IL-4 controls the selective endothelium-driven transmigration of eosinophils from allergic individuals
    • Moser R., Fehr J., Bruijnzeel P. L.B. IL-4 controls the selective endothelium-driven transmigration of eosinophils from allergic individuals. J. Immunol. 1992; 149: 1432 – 1438
    • (1992) J. Immunol. , vol.149 , pp. 1432-1438
    • Moser, R.1    Fehr, J.2    Bruijnzeel, P.L.B.3
  • 238
    • 0025336004 scopus 로고
    • IL-4 regulates endothelial cell activation by IL-1, tumor necrosis factor, or IFN-γ
    • Thornhill M. H., Kaskard D. O. IL-4 regulates endothelial cell activation by IL-1, tumor necrosis factor, or IFN-γ. J. Immunol. 1990; 145: 865 – 872
    • (1990) J. Immunol. , vol.145 , pp. 865-872
    • Thornhill, M.H.1    Kaskard, D.O.2
  • 239
    • 0030444620 scopus 로고    scopus 로고
    • Biological activity of IL-4 and IL-13 on human endothelial cells: functional evidence that both cytokines act through the same receptor
    • Kotowicz K., Callard R. E., Friedrich K., Matthews D. J., Klein N. Biological activity of IL-4 and IL-13 on human endothelial cells: functional evidence that both cytokines act through the same receptor. Int. Immunol. 1996; 8: 1915 – 1925
    • (1996) Int. Immunol. , vol.8 , pp. 1915-1925
    • Kotowicz, K.1    Callard, R.E.2    Friedrich, K.3    Matthews, D.J.4    Klein, N.5
  • 240
    • 0027418575 scopus 로고
    • IL-4 regulates the morphology, cytoskeleton, and proliferation of human umbilical vein endothelial cells: relationship between vimentin and CD23
    • Klein N. J., Rigley K. P., Callard R. E. IL-4 regulates the morphology, cytoskeleton, and proliferation of human umbilical vein endothelial cells: relationship between vimentin and CD23. Int. Immunol. 1993; 5: 293 – 301
    • (1993) Int. Immunol. , vol.5 , pp. 293-301
    • Klein, N.J.1    Rigley, K.P.2    Callard, R.E.3
  • 241
    • 0028861841 scopus 로고
    • Regulation of vascular cell adhesion molecule-1 expression by IL-4 and TNF-alpha in cultured endothelial cells
    • Iademarco M. F., Barks J. L., Dean D. C. Regulation of vascular cell adhesion molecule-1 expression by IL-4 and TNF-alpha in cultured endothelial cells. J. Clin. Invest. 1995; 95: 264 – 271
    • (1995) J. Clin. Invest. , vol.95 , pp. 264-271
    • Iademarco, M.F.1    Barks, J.L.2    Dean, D.C.3
  • 242
    • 0026657616 scopus 로고
    • Effects of tumor necrosis factor, lipopolysaccharide, and IL-4 on the expression of vascular cell adhesion molecule-1 in vivo., Correlation with CD3+ T cell infiltration
    • Briscoe D. M., Cotran R. S., Pober J. S. Effects of tumor necrosis factor, lipopolysaccharide, and IL-4 on the expression of vascular cell adhesion molecule-1 in vivo., Correlation with CD3+ T cell infiltration. J. Immunol. 1992; 149: 2954 – 2960
    • (1992) J. Immunol. , vol.149 , pp. 2954-2960
    • Briscoe, D.M.1    Cotran, R.S.2    Pober, J.S.3
  • 243
    • 0028129414 scopus 로고
    • Regulation of endothelial and mesothelial cell function by interleukin-13: selective induction of vascular cell adhesion molecule-1 and amplification of interleukin-6 production
    • Sironi M., Sciacca F. L., Matteuci C., Conni M., Vecchi A., Bernasconi S., Minty A., Caput D., Ferrara P., Colotta F., Mantovani A. Regulation of endothelial and mesothelial cell function by interleukin-13: selective induction of vascular cell adhesion molecule-1 and amplification of interleukin-6 production. Blood 1994; 84: 1913 – 1921
    • (1994) Blood , vol.84 , pp. 1913-1921
    • Sironi, M.1    Sciacca, F.L.2    Matteuci, C.3    Conni, M.4    Vecchi, A.5    Bernasconi, S.6    Minty, A.7    Caput, D.8    Ferrara, P.9    Colotta, F.10    Mantovani, A.11
  • 244
    • 0026031380 scopus 로고
    • Interleukin 4 induces interleukin 6 production by endothelial cells: synergy with interferon-γ
    • Howells G., Pham P., Taylor D., Foxwell B., Feldman M. Interleukin 4 induces interleukin 6 production by endothelial cells: synergy with interferon-γ. Eur. J. Immunol. 1991; 21: 97 – 101
    • (1991) Eur. J. Immunol. , vol.21 , pp. 97-101
    • Howells, G.1    Pham, P.2    Taylor, D.3    Foxwell, B.4    Feldman, M.5
  • 245
    • 0028814601 scopus 로고
    • Regulation of the production of the RANTES chemokine by endothelial cells. Synergistic induction by IFN-gamma plus TNF-alpha and inhibition by IL-4 and IL-13
    • Marfaing-Koka A., Devergne O., Gorgone G., Portier A., Schall T. J., Galanaud P., Emilie D. Regulation of the production of the RANTES chemokine by endothelial cells. Synergistic induction by IFN-gamma plus TNF-alpha and inhibition by IL-4 and IL-13. J. Immunol. 1995; 154: 1870 – 1878
    • (1995) J. Immunol. , vol.154 , pp. 1870-1878
    • Marfaing-Koka, A.1    Devergne, O.2    Gorgone, G.3    Portier, A.4    Schall, T.J.5    Galanaud, P.6    Emilie, D.7
  • 246
    • 0027296185 scopus 로고
    • IL-4 and IL-13 exhibit comparable abilities to reduce pyrogen-induced expression of procoagulant activity in endothelial cells and monocytes
    • Herbert J. M., Savi P., Laplace M. C., Lale A., Dol F., Dumas A., Labit C., Minty A. IL-4 and IL-13 exhibit comparable abilities to reduce pyrogen-induced expression of procoagulant activity in endothelial cells and monocytes. FEBS Lett. 1993; 328: 268 – 270
    • (1993) FEBS Lett. , vol.328 , pp. 268-270
    • Herbert, J.M.1    Savi, P.2    Laplace, M.C.3    Lale, A.4    Dol, F.5    Dumas, A.6    Labit, C.7    Minty, A.8
  • 248
    • 0025145163 scopus 로고
    • Synergistic effect of IL-4 and IFN-γ on the expression of polymeric Ig receptor (secretory component) and IgA binding by human epithelial cells
    • Phillips J. O., Everson M. P., Moldoveanu Z., Lue C., Mestecky J. Synergistic effect of IL-4 and IFN-γ on the expression of polymeric Ig receptor (secretory component) and IgA binding by human epithelial cells. J. Immunol. 1990; 145: 1740 – 1744
    • (1990) J. Immunol. , vol.145 , pp. 1740-1744
    • Phillips, J.O.1    Everson, M.P.2    Moldoveanu, Z.3    Lue, C.4    Mestecky, J.5
  • 249
    • 0025787986 scopus 로고
    • IL-1, IL-4, and IFN-γ differentially regulate cytokine production and cell surface molecule expression in cultured human thymic epithelial cells
    • Galy A. H., Spits H. IL-1, IL-4, and IFN-γ differentially regulate cytokine production and cell surface molecule expression in cultured human thymic epithelial cells. J. Immunol. 1991; 147: 3823 – 3830
    • (1991) J. Immunol. , vol.147 , pp. 3823-3830
    • Galy, A.H.1    Spits, H.2
  • 250
    • 0029813757 scopus 로고    scopus 로고
    • Interleukin-8 production by the human colon epithelial cell line HT-29: modulation by interleukin-13
    • Kolios G., Robertson D. A., Jordan N. J., Minty A., Caput D., Ferrara P., Westwick J. Interleukin-8 production by the human colon epithelial cell line HT-29: modulation by interleukin-13. Br. J. Immunol. 1996; 119: 351 – 359
    • (1996) Br. J. Immunol. , vol.119 , pp. 351-359
    • Kolios, G.1    Robertson, D.A.2    Jordan, N.J.3    Minty, A.4    Caput, D.5    Ferrara, P.6    Westwick, J.7
  • 251
    • 0029821696 scopus 로고    scopus 로고
    • Inhibition of inducible nitric oxide synthase expression by interleukin-4 and interleukin-13 in human epithelial cells
    • Berkman N. Inhibition of inducible nitric oxide synthase expression by interleukin-4 and interleukin-13 in human epithelial cells. Immunology 1996; 89: 363 – 367
    • (1996) Immunology , vol.89 , pp. 363-367
    • Berkman, N.1
  • 253
    • 0029922844 scopus 로고    scopus 로고
    • Interleukin-4 and interleukin-13 differentially regulate epithelial chloride secretion
    • Zund G., Madara J. L., Dzus A. L., Awtrey C. S., Colgan S. P. Interleukin-4 and interleukin-13 differentially regulate epithelial chloride secretion. J. Biol. Chem. 1996; 271: 7460 – 7464
    • (1996) J. Biol. Chem. , vol.271 , pp. 7460-7464
    • Zund, G.1    Madara, J.L.2    Dzus, A.L.3    Awtrey, C.S.4    Colgan, S.P.5
  • 255
    • 0025874151 scopus 로고
    • Interleukin-4 inhibits stimulation of hepatic lipogenesis by tumor necrosis factor, interleukin-1 and interleukin-6 but not interferon-α
    • Grunfeld C., Soued M., Adi S., Moser A. H., Fiers W., Dinarello C. A., Feingold K. R. Interleukin-4 inhibits stimulation of hepatic lipogenesis by tumor necrosis factor, interleukin-1 and interleukin-6 but not interferon-α. Cancer Res. 1991; 51: 2803 – 2807
    • (1991) Cancer Res. , vol.51 , pp. 2803-2807
    • Grunfeld, C.1    Soued, M.2    Adi, S.3    Moser, A.H.4    Fiers, W.5    Dinarello, C.A.6    Feingold, K.R.7
  • 256
    • 0027443904 scopus 로고
    • Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture
    • Razzak Z. A., Loyer P., Fautrel A., Gautier J. C., Corcos L., Turlin B., Beaune P., Guillouzo A. Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture. Mol. Pharmacol. 1993; 44: 707 – 715
    • (1993) Mol. Pharmacol. , vol.44 , pp. 707-715
    • Razzak, Z.A.1    Loyer, P.2    Fautrel, A.3    Gautier, J.C.4    Corcos, L.5    Turlin, B.6    Beaune, P.7    Guillouzo, A.8
  • 258
    • 0029025420 scopus 로고
    • Down-regulating effects of IL-4 and IL-10 on the IFN-γ response in atopic dermatitis
    • Lester M. R., Hofer M. F., Gately M., Trumble A., Leung D. Y.M. Down-regulating effects of IL-4 and IL-10 on the IFN-γ response in atopic dermatitis. J. Immunol. 1995; 154: 6174 – 6181
    • (1995) J. Immunol. , vol.154 , pp. 6174-6181
    • Lester, M.R.1    Hofer, M.F.2    Gately, M.3    Trumble, A.4    Leung, D.Y.M.5
  • 259
    • 0025806447 scopus 로고
    • Shifts in interleukin-4 and interferon-γ production by T cells of patients with elevated serum IgE levels and the modulatory effects of these lymphokines on spontaneous IgE synthesis
    • Rousset F., Robert J., Andary M., Bonnin J. P., Souillet G., Chretien I., Briere F., Pene J., de Vries J. E. Shifts in interleukin-4 and interferon-γ production by T cells of patients with elevated serum IgE levels and the modulatory effects of these lymphokines on spontaneous IgE synthesis. J. Allergy Clin. Immunol. 1991; 87: 58 – 69
    • (1991) J. Allergy Clin. Immunol. , vol.87 , pp. 58-69
    • Rousset, F.1    Robert, J.2    Andary, M.3    Bonnin, J.P.4    Souillet, G.5    Chretien, I.6    Briere, F.7    Pene, J.8    de Vries, J.E.9
  • 260
    • 0028901793 scopus 로고
    • Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-γ secretion in specific allergen-stimulated T cell cultures
    • Jutel M., Pichler W. J., Skrbic D., Urwyler A., Dahinden C., Müller U. R. Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-γ secretion in specific allergen-stimulated T cell cultures. J. Immunol. 1995; 154: 4187 – 4194
    • (1995) J. Immunol. , vol.154 , pp. 4187-4194
    • Jutel, M.1    Pichler, W.J.2    Skrbic, D.3    Urwyler, A.4    Dahinden, C.5    Müller, U.R.6
  • 261
    • 0027443372 scopus 로고
    • Allergen immunotherapy decreases interleukin 4 production in CD4+ T cells from allergic individuals
    • Secrist H., Chelen C. J., Wen Y., Marshall J. D., Umetsu D. T. Allergen immunotherapy decreases interleukin 4 production in CD4+ T cells from allergic individuals. J. Exp. Med. 1993; 178: 2123 – 2130
    • (1993) J. Exp. Med. , vol.178 , pp. 2123-2130
    • Secrist, H.1    Chelen, C.J.2    Wen, Y.3    Marshall, J.D.4    Umetsu, D.T.5
  • 262
    • 0025734395 scopus 로고
    • Evidence suggesting involvement of interleukin-4 (IL-4) production in spontaneous in vitro, IgE synthesis in patients with atopic dermatitis
    • Vollenweider S., Saurat J. H., Rocken M., Hauser C. Evidence suggesting involvement of interleukin-4 (IL-4) production in spontaneous in vitro, IgE synthesis in patients with atopic dermatitis. J. Allergy Clin. Immunol. 1991; 87: 1088 – 1095
    • (1991) J. Allergy Clin. Immunol. , vol.87 , pp. 1088-1095
    • Vollenweider, S.1    Saurat, J.H.2    Rocken, M.3    Hauser, C.4
  • 264
    • 0026775122 scopus 로고
    • Circulating elevated levels of soluble CD23, interleukin 4, and CD20+ CD23+ lymphocytes in atopic subjects with elevated serum IgE concentrations
    • Reddy M. M., Weissman A. M., Mazza D. S., Meriney D. K., Johns M., Carrabis S., Grieco M. H. Circulating elevated levels of soluble CD23, interleukin 4, and CD20+ CD23+ lymphocytes in atopic subjects with elevated serum IgE concentrations. Ann. Allergy 1992; 69: 131 – 134
    • (1992) Ann. Allergy , vol.69 , pp. 131-134
    • Reddy, M.M.1    Weissman, A.M.2    Mazza, D.S.3    Meriney, D.K.4    Johns, M.5    Carrabis, S.6    Grieco, M.H.7
  • 267
    • 0028931038 scopus 로고
    • Interleukin 4 production by CD4+ T cells from allergic individuals is modulated by antigen concentration and antigen-presenting cell type
    • Secrist H., DeKruyff R. H., Umetsur D. T. Interleukin 4 production by CD4+ T cells from allergic individuals is modulated by antigen concentration and antigen-presenting cell type. J. Exp. Med. 1995; 181: 1081 – 1089
    • (1995) J. Exp. Med. , vol.181 , pp. 1081-1089
    • Secrist, H.1    DeKruyff, R.H.2    Umetsur, D.T.3
  • 269
    • 0024502120 scopus 로고
    • Murine interleukin-4 displays potent anti-tumor activity in vivo
    • Tepper R. I., Pattengale P. K., Leder P. Murine interleukin-4 displays potent anti-tumor activity in vivo. Cell 1989; 57: 503 – 512
    • (1989) Cell , vol.57 , pp. 503-512
    • Tepper, R.I.1    Pattengale, P.K.2    Leder, P.3
  • 270
    • 0026657391 scopus 로고
    • An eosinophil-dependent mechanism for the antitumor effect of interleukin-4
    • Tepper R. I., Coffman R. L., Leder P. An eosinophil-dependent mechanism for the antitumor effect of interleukin-4. Science 1992; 257: 548 – 551
    • (1992) Science , vol.257 , pp. 548-551
    • Tepper, R.I.1    Coffman, R.L.2    Leder, P.3
  • 271
    • 0025119692 scopus 로고
    • Low doses of interleukin 4 injected perilymphatically in tumor-bearing mice inhibit the growth of poorly and apparently nonimmunogenic tumors and induce a tumor-specific immune memory
    • Bosco M. C., Giovarelli M., Forni M., Modesti A., Scarpa G., Masuelli L., Forni G. Low doses of interleukin 4 injected perilymphatically in tumor-bearing mice inhibit the growth of poorly and apparently nonimmunogenic tumors and induce a tumor-specific immune memory. J. Immunol. 1990; 145: 3136 – 3143
    • (1990) J. Immunol. , vol.145 , pp. 3136-3143
    • Bosco, M.C.1    Giovarelli, M.2    Forni, M.3    Modesti, A.4    Scarpa, G.5    Masuelli, L.6    Forni, G.7
  • 275
    • 0025772317 scopus 로고
    • Interleukin 4 suppresses the spontaneous growth of chronic myelomonocytic leukemia cells
    • Akashi K., Shibuya T., Harada M., Takamatsu Y., Uike N., Eto T., Niho Y. Interleukin 4 suppresses the spontaneous growth of chronic myelomonocytic leukemia cells. J. Clin. Invest. 1991; 88: 223 – 230
    • (1991) J. Clin. Invest. , vol.88 , pp. 223-230
    • Akashi, K.1    Shibuya, T.2    Harada, M.3    Takamatsu, Y.4    Uike, N.5    Eto, T.6    Niho, Y.7
  • 276
    • 0027469405 scopus 로고
    • Expression of high affinity interleukin-4 receptors on human renal cell carcinoma cells and inhibition of tumor cell growth in vitro, by interleukin-4
    • Obiri N. I., Hillman G. G., Haas G. P., Sud S., Puri R. K. Expression of high affinity interleukin-4 receptors on human renal cell carcinoma cells and inhibition of tumor cell growth in vitro, by interleukin-4. J. Clin. Invest. 1993; 91: 88 – 93
    • (1993) J. Clin. Invest. , vol.91 , pp. 88-93
    • Obiri, N.I.1    Hillman, G.G.2    Haas, G.P.3    Sud, S.4    Puri, R.K.5
  • 277
    • 0028000624 scopus 로고
    • Interleukin-13 inhibits the proliferation of normal and leukemic human B-cell precursors
    • Renard N., Duvert V., Banchereau J., Saeland S. Interleukin-13 inhibits the proliferation of normal and leukemic human B-cell precursors. Blood 1994; 84: 2253 – 2260
    • (1994) Blood , vol.84 , pp. 2253-2260
    • Renard, N.1    Duvert, V.2    Banchereau, J.3    Saeland, S.4
  • 278
    • 0029777411 scopus 로고    scopus 로고
    • Effects of interleukin-13 on cytokine secretion by human acute myelogenous leukemia blasts
    • Bruserud O. Effects of interleukin-13 on cytokine secretion by human acute myelogenous leukemia blasts. Leukemia 1996; 10: 1497 – 1503
    • (1996) Leukemia , vol.10 , pp. 1497-1503
    • Bruserud, O.1
  • 282
    • 0029934957 scopus 로고    scopus 로고
    • Targeting of interleukin-13 receptor on human renal cell carcinoma cells by a recombinant chimeric protein composed of interleukin-13 and a truncated form of Pseudomonas exotoxin A (PE38QQR)
    • Puri R. K., Leland P., Obiri N. I., Husain S. R., Kreitman R. J., Haas G. P., Pastan I., Debinski W. Targeting of interleukin-13 receptor on human renal cell carcinoma cells by a recombinant chimeric protein composed of interleukin-13 and a truncated form of Pseudomonas exotoxin A (PE38QQR). Blood 1996; 87: 4333 – 4339
    • (1996) Blood , vol.87 , pp. 4333-4339
    • Puri, R.K.1    Leland, P.2    Obiri, N.I.3    Husain, S.R.4    Kreitman, R.J.5    Haas, G.P.6    Pastan, I.7    Debinski, W.8
  • 283
    • 0029146695 scopus 로고
    • Gene therapy of metastatic cancer by in vivo, retroviral gene targeting
    • Hurford R. K., Dranoff G., Mulligan R. C., Tepper R. I. Gene therapy of metastatic cancer by in vivo, retroviral gene targeting. Nature Genetics 1995; 10: 430 – 435
    • (1995) Nature Genetics , vol.10 , pp. 430-435
    • Hurford, R.K.1    Dranoff, G.2    Mulligan, R.C.3    Tepper, R.I.4
  • 284
    • 0026717477 scopus 로고
    • Inhibition of the production of proinflammatory cytokines and immunoglobulins by interleukin-4 in an ex vivo, model of rheumatoid synovitis
    • Miossec P., Briolay J., Dechanet J., Wijdenes J., Martinez-Valdez H., Banchereau J. Inhibition of the production of proinflammatory cytokines and immunoglobulins by interleukin-4 in an ex vivo, model of rheumatoid synovitis. Arthritis Rheum. 1992; 35: 874 – 883
    • (1992) Arthritis Rheum. , vol.35 , pp. 874-883
    • Miossec, P.1    Briolay, J.2    Dechanet, J.3    Wijdenes, J.4    Martinez-Valdez, H.5    Banchereau, J.6
  • 285
    • 0028930076 scopus 로고
    • Regulatory effects of IL-13 on synovial fluid macrophages and blood monocytes from patients with inflammatory arthritis
    • Hart P. H., Ahernn M. J., Smith M. D., Finlay-Jones J. J. Regulatory effects of IL-13 on synovial fluid macrophages and blood monocytes from patients with inflammatory arthritis. Clin. Exp. Immunol. 1995; 99: 331 – 337
    • (1995) Clin. Exp. Immunol. , vol.99 , pp. 331-337
    • Hart, P.H.1    Ahernn, M.J.2    Smith, M.D.3    Finlay-Jones, J.J.4
  • 286
    • 0029163574 scopus 로고
    • Differential effects of interleukins 10 and 4 on the production of interleukin-6 by blood and synovium monocytes in rheumatoid arthritis
    • Chomarat P., Banchereau J., Miossec P. Differential effects of interleukins 10 and 4 on the production of interleukin-6 by blood and synovium monocytes in rheumatoid arthritis. Arthritis Rheum. 1995; 38: 1046 – 1054
    • (1995) Arthritis Rheum. , vol.38 , pp. 1046-1054
    • Chomarat, P.1    Banchereau, J.2    Miossec, P.3
  • 287
    • 0029999293 scopus 로고    scopus 로고
    • Immunoregulatory properties of IL-13 in patients with inflammatory bowel disease; comparison with IL-4 and IL-10
    • Kucharzik T., Lügering N., Weigelt H., Adolf M., Domschke W., Stoll R. Immunoregulatory properties of IL-13 in patients with inflammatory bowel disease; comparison with IL-4 and IL-10. Clin. Exp. Immunol. 1996; 104: 483 – 490
    • (1996) Clin. Exp. Immunol. , vol.104 , pp. 483-490
    • Kucharzik, T.1    Lügering, N.2    Weigelt, H.3    Adolf, M.4    Domschke, W.5    Stoll, R.6
  • 288
    • 0029740959 scopus 로고    scopus 로고
    • The presence of interleukin-13 in rheumatoid synovium and its antiinflammatory effects on synovial fluid macrophages from patients with rheumatoid arthritis
    • Isomaki P., Luukkainen R., Toivanen P., Punnonen J. The presence of interleukin-13 in rheumatoid synovium and its antiinflammatory effects on synovial fluid macrophages from patients with rheumatoid arthritis. Arthritis Rheum. 1996; 39: 1693 – 1702
    • (1996) Arthritis Rheum. , vol.39 , pp. 1693-1702
    • Isomaki, P.1    Luukkainen, R.2    Toivanen, P.3    Punnonen, J.4
  • 289
    • 0028061264 scopus 로고
    • Interleukin 4 inhibits bone resorption through an effect on osteoclasts and proinflammatory cytokines in an ex vivo, model of bone resorption in rheumatoid arthritis
    • Miossec P., Chomarat P., Dechanet J., Moreau J. F., Roux J. P., Delmas P., Banchereau J. Interleukin 4 inhibits bone resorption through an effect on osteoclasts and proinflammatory cytokines in an ex vivo, model of bone resorption in rheumatoid arthritis. Arthritis Rheum. 1994; 37: 1715 – 1722
    • (1994) Arthritis Rheum. , vol.37 , pp. 1715-1722
    • Miossec, P.1    Chomarat, P.2    Dechanet, J.3    Moreau, J.F.4    Roux, J.P.5    Delmas, P.6    Banchereau, J.7
  • 290
    • 0028978683 scopus 로고
    • Interleukin-4, interferon-gamma, and prostaglandin E impact the osteoclastic cell-forming potential of murine bone marrow macrophages
    • Lacey D. L., Erdmann J. M., Teitelbaum S. L., Tan H. L., Ohara J., Shioi A. Interleukin-4, interferon-gamma, and prostaglandin E impact the osteoclastic cell-forming potential of murine bone marrow macrophages. Endocrinology 1995; 136: 2367 – 2376
    • (1995) Endocrinology , vol.136 , pp. 2367-2376
    • Lacey, D.L.1    Erdmann, J.M.2    Teitelbaum, S.L.3    Tan, H.L.4    Ohara, J.5    Shioi, A.6
  • 292
  • 293
    • 0028876611 scopus 로고
    • Retinoid treatment of experimental allergic encephalomyelitis. IL-4 production correlates with improved disease course
    • Racke M. K., Burnett D., Pak S. H., Albert P. S., Cannella B., Raine C. S., McFarlin D. E., Scott D. E. Retinoid treatment of experimental allergic encephalomyelitis. IL-4 production correlates with improved disease course. J. Immunol. 1995; 154: 450 – 458
    • (1995) J. Immunol. , vol.154 , pp. 450-458
    • Racke, M.K.1    Burnett, D.2    Pak, S.H.3    Albert, P.S.4    Cannella, B.5    Raine, C.S.6    McFarlin, D.E.7    Scott, D.E.8
  • 295
    • 0028089802 scopus 로고
    • Macrophage-inactivating IL-13 suppresses experimental autoimmune encephalomyelitis in rats
    • Cash E., Minty A., Ferrara P., Caput D., Fradelizi D., Rott O. Macrophage-inactivating IL-13 suppresses experimental autoimmune encephalomyelitis in rats. J. Immunol. 1994; 153: 4258 – 4267
    • (1994) J. Immunol. , vol.153 , pp. 4258-4267
    • Cash, E.1    Minty, A.2    Ferrara, P.3    Caput, D.4    Fradelizi, D.5    Rott, O.6
  • 296
    • 0029030964 scopus 로고
    • T helper cell subsets in insulin-dependent diabetes
    • Katz J. D., Benoist C., Mathis D. T helper cell subsets in insulin-dependent diabetes. Science 1995; 268: 1185 – 1188
    • (1995) Science , vol.268 , pp. 1185-1188
    • Katz, J.D.1    Benoist, C.2    Mathis, D.3
  • 297
    • 0027370379 scopus 로고
    • Suppression of monocyte function and differential regulation of IL-1 and IL-1ra by IL-4 contribute to resolution of experimental arthritis
    • Allen J. B., Wong H. L., Costa G. L., Bienkowski M. J., Wahl S. M. Suppression of monocyte function and differential regulation of IL-1 and IL-1ra by IL-4 contribute to resolution of experimental arthritis. J. Immunol. 1993; 151: 4344 – 4351
    • (1993) J. Immunol. , vol.151 , pp. 4344-4351
    • Allen, J.B.1    Wong, H.L.2    Costa, G.L.3    Bienkowski, M.J.4    Wahl, S.M.5
  • 298
    • 0029797868 scopus 로고    scopus 로고
    • Attenuation of collagen-induced arthritis in mice by treatment with vector cells engineered to secrete interleukin-13
    • Bessis N., Boissier M. C., Ferrara P., Blankenstein T., Fradelizi D., Fournier C. Attenuation of collagen-induced arthritis in mice by treatment with vector cells engineered to secrete interleukin-13. Eur. J. Immunol. 1996; 26: 2399 – 2403
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2399-2403
    • Bessis, N.1    Boissier, M.C.2    Ferrara, P.3    Blankenstein, T.4    Fradelizi, D.5    Fournier, C.6
  • 299
    • 0027508426 scopus 로고
    • Protective effects of IL-4 and IL-10 against immune complex-induced lung injury
    • Mulligan M. S., Jones M. L., Vaporciyan A. A., Howard M. C., Ward P. A. Protective effects of IL-4 and IL-10 against immune complex-induced lung injury. J. Immunol. 1993; 151: 5666 – 5674
    • (1993) J. Immunol. , vol.151 , pp. 5666-5674
    • Mulligan, M.S.1    Jones, M.L.2    Vaporciyan, A.A.3    Howard, M.C.4    Ward, P.A.5


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