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Volumn 159, Issue 7, 1997, Pages 3434-3443

Characterization of T Cell-Mediated Responses in Nonhealing and Healing Leishmania major Infections in the Absence of Endogenous IL-4

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CYTOKINE; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 12; INTERLEUKIN 4; MONOCLONAL ANTIBODY;

EID: 0031255049     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (47)

References (70)
  • 1
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted protein
    • Mosmann, T. R., H. Cherwinski, M. W. Bond, M. A. Giedlin, and R. L. Coffman. 1986. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted protein. J. Immunol. 136:2348.
    • (1986) J. Immunol. , vol.136 , pp. 2348
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 2
    • 0024353079 scopus 로고
    • TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • Mosmann, T. R., and R. L. Coffman. 1989. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145.
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 145
    • Mosmann, T.R.1    Coffman, R.L.2
  • 3
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas, A. K., K. M. Murphy, and A. Sher. 1996. Functional diversity of helper T lymphocytes. Nature 383:787.
    • (1996) Nature , vol.383 , pp. 787
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 8
    • 0026500979 scopus 로고
    • IL-4 induces a Th2 response in Leishmania major-infected mice
    • Chatelain, R., K. Varkila, and R. L. Coffman. 1992. IL-4 induces a Th2 response in Leishmania major-infected mice. J. Immunol. 148:1182.
    • (1992) J. Immunol. , vol.148 , pp. 1182
    • Chatelain, R.1    Varkila, K.2    Coffman, R.L.3
  • 9
    • 0029149075 scopus 로고
    • Induction of Th2 responses in infectious diseases
    • Pearce, E. J., and S. L. Reiner. 1995. Induction of Th2 responses in infectious diseases. Curr. Opin. Immunol. 7:497.
    • (1995) Curr. Opin. Immunol. , vol.7 , pp. 497
    • Pearce, E.J.1    Reiner, S.L.2
  • 11
    • 0024589297 scopus 로고
    • + T cells in leishmaniasis
    • + T cells in leishmaniasis. Immunol. Today 10:40.
    • (1989) Immunol. Today , vol.10 , pp. 40
    • Liew, F.Y.1
  • 14
    • 0028933795 scopus 로고
    • The regulation of immunity to Leishmania major
    • Reiner, S. L., and R. M. Locksley. 1995. The regulation of immunity to Leishmania major. Annu. Rev. Immunol. 13:151.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 151
    • Reiner, S.L.1    Locksley, R.M.2
  • 15
    • 0024412797 scopus 로고
    • Administration of monoclonal anti-IFN-γ antibodies in vivo abrogates resistance of C3H/HeN mice to infection with Leishmania major
    • Belosevic, M., D. S. Finbloom, P. H. van der Meide, M. V. Slayter, and C. A. Nacy. 1989. Administration of monoclonal anti-IFN-γ antibodies in vivo abrogates resistance of C3H/HeN mice to infection with Leishmania major. J. Immunol. 143:266.
    • (1989) J. Immunol. , vol.143 , pp. 266
    • Belosevic, M.1    Finbloom, D.S.2    Van Der Meide, P.H.3    Slayter, M.V.4    Nacy, C.A.5
  • 16
    • 0024391966 scopus 로고
    • T-cell responses and immunity to experimental infection with Leishmania major
    • Müller, I., T. Pedrazzini, J. P. Farrell, and J. Louis. 1989. T-cell responses and immunity to experimental infection with Leishmania major. Annu. Rev. Immunol. 7:561.
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 561
    • Müller, I.1    Pedrazzini, T.2    Farrell, J.P.3    Louis, J.4
  • 17
    • 0024372986 scopus 로고
    • + T cell clones recognizing antigen(s) associated with live parasites
    • + T cell clones recognizing antigen(s) associated with live parasites. Eur. J. Immunol. 19:865.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 865
    • Müller, I.1    Louis, J.A.2
  • 18
  • 20
    • 0027135979 scopus 로고
    • Cytokines in leishmaniasis: A complex network of stimulatory and inhibitory interactions
    • Bogdan, C., A. Gessner, and M. Röllinghoff. 1993. Cytokines in leishmaniasis: a complex network of stimulatory and inhibitory interactions. Immunobiology 189: 356.
    • (1993) Immunobiology , vol.189 , pp. 356
    • Bogdan, C.1    Gessner, A.2    Röllinghoff, M.3
  • 22
    • 0025133974 scopus 로고
    • Cure of murine leishmaniasis with anti-interleukin-4 monoclonal antibody: Evidence for a T-cell-dependent, interferon-γ-independent mechanism
    • Sadick, M. D., F. P. Heinzel, B. J. Holaday, R. T. Pu, R. S. Dawkins, and R. M. Locksley. 1990. Cure of murine leishmaniasis with anti-interleukin-4 monoclonal antibody: evidence for a T-cell-dependent, interferon-γ-independent mechanism. J. Exp. Med. 171:115.
    • (1990) J. Exp. Med. , vol.171 , pp. 115
    • Sadick, M.D.1    Heinzel, F.P.2    Holaday, B.J.3    Pu, R.T.4    Dawkins, R.S.5    Locksley, R.M.6
  • 24
    • 0027945732 scopus 로고
    • Depletion of interleukin-4 in BALB/c mice with established Leishmania major infections increases the efficacy of antimony therapy and promotes Th1-like responses
    • Nabors, G. S., and J. P. Farrell. 1994. Depletion of interleukin-4 in BALB/c mice with established Leishmania major infections increases the efficacy of antimony therapy and promotes Th1-like responses. Infect. Immun. 62:5498.
    • (1994) Infect. Immun. , vol.62 , pp. 5498
    • Nabors, G.S.1    Farrell, J.P.2
  • 25
    • 0030023112 scopus 로고    scopus 로고
    • Susceptibility to Leishmania major infection in interleukin-4 deficient mice
    • Noben-Trauth, N., P. Kropf, and I. Müller 1996. Susceptibility to Leishmania major infection in interleukin-4 deficient mice. Science 271:987.
    • (1996) Science , vol.271 , pp. 987
    • Noben-Trauth, N.1    Kropf, P.2    Müller, I.3
  • 26
    • 0029071483 scopus 로고
    • Developmental commitment to the Th2 lineage by extinction of IL-12 signaling
    • Szabo, S. J., N. G. Jacobson, A. S. Dighe, U. Gubler, and K. M. Murphy. 1995. Developmental commitment to the Th2 lineage by extinction of IL-12 signaling. Immunity 2:665.
    • (1995) Immunity , vol.2 , pp. 665
    • Szabo, S.J.1    Jacobson, N.G.2    Dighe, A.S.3    Gubler, U.4    Murphy, K.M.5
  • 27
    • 0022400673 scopus 로고
    • Therapeutic effect of anti-L3T4 monoclonal antibody GK1.5 on cutaneous leishmaniasis in genetically susceptible BALB/c mice
    • Titus, R. G., Rh. Ceredig, J. C. Cerottini, and J. A. Louis. 1985. Therapeutic effect of anti-L3T4 monoclonal antibody GK1.5 on cutaneous leishmaniasis in genetically susceptible BALB/c mice. J. Immunol. 135:2108.
    • (1985) J. Immunol. , vol.135 , pp. 2108
    • Titus, R.G.1    Ceredig, R.2    Cerottini, J.C.3    Louis, J.A.4
  • 28
    • 0023724978 scopus 로고
    • + T cells that promote parasite growth distinct from those mediating resistance?
    • + T cells that promote parasite growth distinct from those mediating resistance? Immunol. Lett. 19:251.
    • (1988) Immunol. Lett. , vol.19 , pp. 251
    • Müller, I.1    Pedrazzini, T.2    Louis, J.A.3
  • 32
    • 0030298210 scopus 로고    scopus 로고
    • Efficient targeting of the IL-4 gene in a BALB/c embryonic stem cell line
    • Noben-Trauth, N., G. Köhler, K. Bürki, and B. Ledermann. 1996. Efficient targeting of the IL-4 gene in a BALB/c embryonic stem cell line. Transgenic Res. 5:487.
    • (1996) Transgenic Res. , vol.5 , pp. 487
    • Noben-Trauth, N.1    Köhler, G.2    Bürki, K.3    Ledermann, B.4
  • 33
    • 0018571965 scopus 로고
    • Recognition of protozoan parasite antigens by murine T lymphocytes. I. Induction of specific T lymphocyte dependent proliferative response to Leishmania tropica
    • Louis, J. A., E. Moedder, R. Behin, and H. Engers. 1979. Recognition of protozoan parasite antigens by murine T lymphocytes. I. Induction of specific T lymphocyte dependent proliferative response to Leishmania tropica. Eur. J. Immunol. 9:841.
    • (1979) Eur. J. Immunol. , vol.9 , pp. 841
    • Louis, J.A.1    Moedder, E.2    Behin, R.3    Engers, H.4
  • 34
    • 0018745489 scopus 로고
    • Cutaneous leishmaniasis: A case with persistent organisms after treatment in presence of normal immune response
    • Neva, F. A., D. Wyler, and T. Nash. 1979. Cutaneous leishmaniasis: a case with persistent organisms after treatment in presence of normal immune response. Am. J. Trop. Med. Hyg. 28:467.
    • (1979) Am. J. Trop. Med. Hyg. , vol.28 , pp. 467
    • Neva, F.A.1    Wyler, D.2    Nash, T.3
  • 35
    • 0021691659 scopus 로고
    • Cell contact mediated macrophage activation for antileishmanial defense. I. Lymphocyte effector mechanism that is contact dependent and noncytotoxic
    • Panosian, C. B., J. P. Sypek, and D. J. Wyler. 1984. Cell contact mediated macrophage activation for antileishmanial defense. I. Lymphocyte effector mechanism that is contact dependent and noncytotoxic. J. Immunol. 133:3358.
    • (1984) J. Immunol. , vol.133 , pp. 3358
    • Panosian, C.B.1    Sypek, J.P.2    Wyler, D.J.3
  • 36
    • 0023619138 scopus 로고
    • The generation of infective stage Leishmania major promastigotes is associated with the cell-surface expression and release of a developmentally regulated glycolipid
    • Sacks, D. L., and R. P. Da Silva. 1987. The generation of infective stage Leishmania major promastigotes is associated with the cell-surface expression and release of a developmentally regulated glycolipid. J. Immunol. 139:3099.
    • (1987) J. Immunol. , vol.139 , pp. 3099
    • Sacks, D.L.1    Da Silva, R.P.2
  • 37
    • 0023872192 scopus 로고
    • Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5 using modified cDNA expression vectors
    • Karasuyama, H., and F. Melchers. 1988. Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5 using modified cDNA expression vectors. Eur. J. Immunol. 18:97.
    • (1988) Eur. J. Immunol. , vol.18 , pp. 97
    • Karasuyama, H.1    Melchers, F.2
  • 38
    • 0023716831 scopus 로고
    • Highly efficient action of autocrine mouse interferon-γ expressed via a retroviral vector
    • Watanabe, Y., and T. Sakata. 1988. Highly efficient action of autocrine mouse interferon-γ expressed via a retroviral vector. Eur. J. Immunol. 18:1627.
    • (1988) Eur. J. Immunol. , vol.18 , pp. 1627
    • Watanabe, Y.1    Sakata, T.2
  • 40
    • 0021234635 scopus 로고
    • Monoclonal antibody to murine gamma interferon inhibits lymphokine-induced antiviral and macrophage tumoricidal activities
    • Spitalny, G. L., and E. A. Havell. 1984. Monoclonal antibody to murine gamma interferon inhibits lymphokine-induced antiviral and macrophage tumoricidal activities. J. Exp. Med. 159:1560.
    • (1984) J. Exp. Med. , vol.159 , pp. 1560
    • Spitalny, G.L.1    Havell, E.A.2
  • 42
    • 0021052516 scopus 로고
    • Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: Similarity of L3T4 to the human Leu3/T4 molecule
    • Dialynas, D. P., Z. S. Quan, K. A. Wall, A. Pierres, J. Quintans, M. R. Loken, M. Pierres, and F. W. Fitch. 1983. Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu3/T4 molecule. J. Immunol. 131:2445.
    • (1983) J. Immunol. , vol.131 , pp. 2445
    • Dialynas, D.P.1    Quan, Z.S.2    Wall, K.A.3    Pierres, A.4    Quintans, J.5    Loken, M.R.6    Pierres, M.7    Fitch, F.W.8
  • 43
    • 0024455588 scopus 로고
    • Production of interferon-γ during infection of mice with Plasmodium chabaudi chabaudi
    • Slade, S. S., and J. Langhorne. 1989. Production of interferon-γ during infection of mice with Plasmodium chabaudi chabaudi. Immunobiology 179:353.
    • (1989) Immunobiology , vol.179 , pp. 353
    • Slade, S.S.1    Langhorne, J.2
  • 44
    • 0022234330 scopus 로고
    • A limiting dilution assay for quantifying Leishmania major in tissues of infected mice
    • Titus, R. G., M. Marchand, T. Boon, and J. A. Louis. 1985. A limiting dilution assay for quantifying Leishmania major in tissues of infected mice. Parasite Immunol. 7:545.
    • (1985) Parasite Immunol. , vol.7 , pp. 545
    • Titus, R.G.1    Marchand, M.2    Boon, T.3    Louis, J.A.4
  • 45
    • 0019468220 scopus 로고
    • Limiting dilution assay for the determination of immunocompetent cell frequencies. I. Data analysis
    • Taswell, C. 1981. Limiting dilution assay for the determination of immunocompetent cell frequencies. I. Data analysis. J. Immunol. 126:1614.
    • (1981) J. Immunol. , vol.126 , pp. 1614
    • Taswell, C.1
  • 46
    • 0027197436 scopus 로고
    • Interleukin-12/T cell stimulating factor, a cytokine with multiple effects on T helper type 1 (Th1) but not on Th2 cells
    • Germann, T., M. K. Gately, D. S. Schoenhaut, M. Lohoff, F. Mattner, S.-C. Jin, E. Schmitt, and E. Rüde. 1994. Interleukin-12/T cell stimulating factor, a cytokine with multiple effects on T helper type 1 (Th1) but not on Th2 cells. Eur. J. Immunol. 23:1762.
    • (1994) Eur. J. Immunol. , vol.23 , pp. 1762
    • Germann, T.1    Gately, M.K.2    Schoenhaut, D.S.3    Lohoff, M.4    Mattner, F.5    Jin, S.-C.6    Schmitt, E.7    Rüde, E.8
  • 49
    • 0029034041 scopus 로고
    • Immunity to intracellular microbial pathogens
    • Kaufmann, S. H. E. 1995. Immunity to intracellular microbial pathogens. Immunol. Today 16:338.
    • (1995) Immunol. Today , vol.16 , pp. 338
    • Kaufmann, S.H.E.1
  • 50
    • 0030266857 scopus 로고    scopus 로고
    • Differential roles for IL-12 in the maintenance of immune responses in infectious versus autoimmune disease
    • Seder, R. A., B. L. Kelsall, and D. Jankovic. 1996. Differential roles for IL-12 in the maintenance of immune responses in infectious versus autoimmune disease. J. Immunol. 157:2745.
    • (1996) J. Immunol. , vol.157 , pp. 2745
    • Seder, R.A.1    Kelsall, B.L.2    Jankovic, D.3
  • 51
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
    • Trinchieri, G. 1995. Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 13:251.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 251
    • Trinchieri, G.1
  • 54
    • 0029937829 scopus 로고    scopus 로고
    • Th cell development and regulation in experimental cutaneous leishmaniasis
    • S. Romagnani, ed. S. Karger, Basel
    • Scott, P. 1996. Th cell development and regulation in experimental cutaneous leishmaniasis. In Th1 and Th2 Cells in Health and Disease, Vol. 63: Chemical Immunology. S. Romagnani, ed. S. Karger, Basel, p. 98.
    • (1996) Th1 and Th2 Cells in Health and Disease, Vol. 63: Chemical Immunology , vol.63 , pp. 98
    • Scott, P.1
  • 55
    • 0030298147 scopus 로고    scopus 로고
    • Early IL-4 production does not predict susceptibility to Leishmania major
    • Scott, P., A. Eaton, W. C. Gause, X. diZhou, and B. Hondowicz. 1996. Early IL-4 production does not predict susceptibility to Leishmania major. Exp. Parasitol. 84:178.
    • (1996) Exp. Parasitol. , vol.84 , pp. 178
    • Scott, P.1    Eaton, A.2    Gause, W.C.3    DiZhou, X.4    Hondowicz, B.5
  • 56
    • 0028982517 scopus 로고
    • Th1 and Th2 subsets: Paradigms lost?
    • Kelso, A. 1995. Th1 and Th2 subsets: paradigms lost? Immunol. Today 16:371.
    • (1995) Immunol. Today , vol.16 , pp. 371
    • Kelso, A.1
  • 58
    • 0025760597 scopus 로고
    • Production of IL-1α by activated Th type 2 cells: Its role as an autocrine growth factor
    • Zubiaga, A. M., E. Munoz, and B. T. Huber. 1991. Production of IL-1α by activated Th type 2 cells: its role as an autocrine growth factor. J. Immunol. 146:3849.
    • (1991) J. Immunol. , vol.146 , pp. 3849
    • Zubiaga, A.M.1    Munoz, E.2    Huber, B.T.3
  • 61
    • 0029783225 scopus 로고    scopus 로고
    • TcR- and IL-1-mediated co-stimulation reveals an IL-4-independent way of Th2 cell proliferation
    • Huber, M., A. Rutherford, W. Meister, A. Weiss, M. Röllinghoff, and M. Lohoff. 1996. TcR-and IL-1-mediated co-stimulation reveals an IL-4-independent way of Th2 cell proliferation. Int. Immunol. 8:1257.
    • (1996) Int. Immunol. , vol.8 , pp. 1257
    • Huber, M.1    Rutherford, A.2    Meister, W.3    Weiss, A.4    Röllinghoff, M.5    Lohoff, M.6
  • 63
    • 0024340791 scopus 로고
    • CR1, the C3b receptor mediates binding of infective Leishmania major metacyclic promastigotes to human macrophages
    • DaSilva, R. P., B. F. Hall, K. A. Joiner, and D. L. Sacks. 1989. CR1, the C3b receptor mediates binding of infective Leishmania major metacyclic promastigotes to human macrophages. J. Immunol. 143:617.
    • (1989) J. Immunol. , vol.143 , pp. 617
    • DaSilva, R.P.1    Hall, B.F.2    Joiner, K.A.3    Sacks, D.L.4
  • 65
    • 0029937829 scopus 로고    scopus 로고
    • Th cell development and regulation in experimental cutaneous leishmaniasis
    • S. Romagnani, ed. S. Karger, Basel
    • Scott, P. 1996. Th cell development and regulation in experimental cutaneous leishmaniasis. In Th1 and Th2 Cells in Health and Disease. Vol. 63: Chemical Immunology. S. Romagnani, ed. S. Karger, Basel, p. 98.
    • (1996) Th1 and Th2 Cells in Health and Disease. Vol. 63: Chemical Immunology , vol.63 , pp. 98
    • Scott, P.1
  • 66
    • 0030021084 scopus 로고
    • Leishmania promastigotes selectively inhibit interleukin-12 induction in bone marrow-derived macrophages from susceptible and resistant mice
    • Carrera, L., R. T. Gazzinelli, R. Badolato, S. Hieny, W. Müller, R. Kühn, and D. L. Sacks. 1995. Leishmania promastigotes selectively inhibit interleukin-12 induction in bone marrow-derived macrophages from susceptible and resistant mice. J. Exp. Med. 183:515.
    • (1995) J. Exp. Med. , vol.183 , pp. 515
    • Carrera, L.1    Gazzinelli, R.T.2    Badolato, R.3    Hieny, S.4    Müller, W.5    Kühn, R.6    Sacks, D.L.7
  • 67
    • 0029077326 scopus 로고
    • IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis
    • Scharton-Kersten, T., L. C. C. Afonso, M. Wysocka, G. Trinchieri, and P. Scott. 1995. IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis. J. Immunol. 154:5320.
    • (1995) J. Immunol. , vol.154 , pp. 5320
    • Scharton-Kersten, T.1    Afonso, L.C.C.2    Wysocka, M.3    Trinchieri, G.4    Scott, P.5
  • 68
    • 0031054302 scopus 로고    scopus 로고
    • Interferon-γ and interleukin-4 regulate T cell interleukin-12 responsiveness through the differential modulation of high-affinity interleukin-12 receptor expression
    • Gollob, J. A., H. Kawasaki, and J. Ritz. 1997. Interferon-γ and interleukin-4 regulate T cell interleukin-12 responsiveness through the differential modulation of high-affinity interleukin-12 receptor expression. Eur. J. Immunol. 27:647.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 647
    • Gollob, J.A.1    Kawasaki, H.2    Ritz, J.3
  • 69
    • 0028934155 scopus 로고
    • Switch from a type 2 to a type 1 T helper cell response and cure of established Leishmania major infection in mice is induced by combined therapy with interleukin 12 and pentostam
    • Nabors, G. S., L. C. C. Afonso, J. P. Farrell, and P. Scott. 1995. Switch from a type 2 to a type 1 T helper cell response and cure of established Leishmania major infection in mice is induced by combined therapy with interleukin 12 and pentostam. Proc. Natl. Acad. Sci. USA 92:3142.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3142
    • Nabors, G.S.1    Afonso, L.C.C.2    Farrell, J.P.3    Scott, P.4
  • 70
    • 0027472336 scopus 로고
    • Interleukin-4 transgenic mice of resistant background are susceptible to Leishmania major infection
    • Leal, L. M. C. C., D. W. Moss, R. Kuhn, W. Müller, and F. Y. Liew. 1993. Interleukin-4 transgenic mice of resistant background are susceptible to Leishmania major infection. Eur. J. Immunol. 23:566.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 566
    • Leal, L.M.C.C.1    Moss, D.W.2    Kuhn, R.3    Müller, W.4    Liew, F.Y.5


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