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Volumn 189, Issue 5, 1999, Pages 803-810

T helper cell type 1-associated and cytotoxic T lymphocyte-mediated tumor immunity is impaired in interleukin 4-deficient mice

Author keywords

Interleukin 4; Interleukin 4 deficient mice; T cell immunity; Tumor vaccination

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 4;

EID: 0345628580     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.189.5.803     Document Type: Article
Times cited : (153)

References (48)
  • 2
    • 0002044055 scopus 로고
    • Tumor immunology
    • W.E. Paul, editor. Raven Press, New York
    • Schreiber, H. 1993. Tumor immunology. In Fundamental Immunology, Third Edition. W.E. Paul, editor. Raven Press, New York. 1143-1178.
    • (1993) Fundamental Immunology, Third Edition , pp. 1143-1178
    • Schreiber, H.1
  • 3
    • 0032473562 scopus 로고    scopus 로고
    • Specific T helper cell requirement for optimal induction of cytotoxic T lymphocytes against major histocompatibility complex class II negative tumors
    • Ossendorp, F., E. Mengede, M. Camps, R. Filius, and C.J. Melief. 1998. Specific T helper cell requirement for optimal induction of cytotoxic T lymphocytes against major histocompatibility complex class II negative tumors. J. Exp. Med. 187:693-702.
    • (1998) J. Exp. Med. , vol.187 , pp. 693-702
    • Ossendorp, F.1    Mengede, E.2    Camps, M.3    Filius, R.4    Melief, C.J.5
  • 5
    • 0027394642 scopus 로고
    • Vaccinations with tumor cells genetically engineered to produce different cytokines: Effectivity not superior to a classical adjuvant
    • Hock, H., M. Dorsch, U. Kunzendorf, K. Überla, Z. Qin, T. Diamantstein, and T. Blankenstein. 1993. Vaccinations with tumor cells genetically engineered to produce different cytokines: effectivity not superior to a classical adjuvant. Cancer Res. 53:714-716.
    • (1993) Cancer Res. , vol.53 , pp. 714-716
    • Hock, H.1    Dorsch, M.2    Kunzendorf, U.3    Überla, K.4    Qin, Z.5    Diamantstein, T.6    Blankenstein, T.7
  • 6
    • 0027487856 scopus 로고
    • Protective and curative potential of vaccination with interleukin-2-gene-transfected cells from a spontaneous mouse mammary adenocarcinoma
    • Cavallo, F., F. Di Pierro, M. Giovarelli, A. Gulino, A. Vacca, A. Stoppacciaro, M. Forni, A. Modesti, and G. Forni. 1993. Protective and curative potential of vaccination with interleukin-2-gene-transfected cells from a spontaneous mouse mammary adenocarcinoma. Cancer Res. 53:5067-5070.
    • (1993) Cancer Res. , vol.53 , pp. 5067-5070
    • Cavallo, F.1    Di Pierro, F.2    Giovarelli, M.3    Gulino, A.4    Vacca, A.5    Stoppacciaro, A.6    Forni, M.7    Modesti, A.8    Forni, G.9
  • 7
    • 0032502844 scopus 로고    scopus 로고
    • Double suicide gene (cytosine deaminase and herpes simplex virus thymidine kinase) but not single gene transfer allows reliable elimination of tumor cells in vivo
    • Uckert, W., T. Kammertöns, K. Haack, Z. Qin, J. Gebert, D.J. Schendel, and T. Blankenstein. 1998. Double suicide gene (cytosine deaminase and herpes simplex virus thymidine kinase) but not single gene transfer allows reliable elimination of tumor cells in vivo. Hum. Gene Ther. 9:855-865.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 855-865
    • Uckert, W.1    Kammertöns, T.2    Haack, K.3    Qin, Z.4    Gebert, J.5    Schendel, D.J.6    Blankenstein, T.7
  • 9
    • 0017126775 scopus 로고
    • Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay
    • Bevan, M.J. 1976. Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay. J. Exp. Med. 143: 1283-1288.
    • (1976) J. Exp. Med. , vol.143 , pp. 1283-1288
    • Bevan, M.J.1
  • 10
    • 0028179056 scopus 로고
    • Role of bone marrow-derived cells in presenting MHG class I-restricted tumor antigens
    • Huang, A.Y., P. Golumbek, M. Ahmadzadeh, E. Jaffee, D. Pardoll, and H. Levitsky. 1994. Role of bone marrow-derived cells in presenting MHG class I-restricted tumor antigens. Science. 264:961-965.
    • (1994) Science , vol.264 , pp. 961-965
    • Huang, A.Y.1    Golumbek, P.2    Ahmadzadeh, M.3    Jaffee, E.4    Pardoll, D.5    Levitsky, H.6
  • 11
    • 0031569119 scopus 로고    scopus 로고
    • Influence of gene-modified (IL-7, IL-4, and B7) tumor cell vaccines on tumor antigen presentation
    • Cayeux, S., G. Richter, G. Noffz, B. Dörken, and T. Blankenstein. 1997. Influence of gene-modified (IL-7, IL-4, and B7) tumor cell vaccines on tumor antigen presentation. J. Immunol. 158:2834-2841.
    • (1997) J. Immunol. , vol.158 , pp. 2834-2841
    • Cayeux, S.1    Richter, G.2    Noffz, G.3    Dörken, B.4    Blankenstein, T.5
  • 15
    • 0032482474 scopus 로고    scopus 로고
    • T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions
    • Schoenberger, S.P., R.E. Toes, E. van der Voort, R. Offringa, and C.J. Melief. 1998. T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature. 393:480-483.
    • (1998) Nature , vol.393 , pp. 480-483
    • Schoenberger, S.P.1    Toes, R.E.2    Van Der Voort, E.3    Offringa, R.4    Melief, C.J.5
  • 16
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • Mosmann, T.R., H. Cherwinski, M.W. Bond, M.A. Giedlin, and R.L. Coffman. 1986. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 136:2348-2357.
    • (1986) J. Immunol. , vol.136 , pp. 2348-2357
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 17
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas, A.K., K.M. Murphy, and A. Sher. 1996. Functional diversity of helper T lymphocytes. Nature. 383:787-793.
    • (1996) Nature , vol.383 , pp. 787-793
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 18
    • 0032033419 scopus 로고    scopus 로고
    • Cytokines induce the development of functionally heterogeneous T helper cell subsets
    • O'Garra, A. 1998. Cytokines induce the development of functionally heterogeneous T helper cell subsets. Immunity. 8:275-283.
    • (1998) Immunity , vol.8 , pp. 275-283
    • O'Garra, A.1
  • 20
    • 0026708718 scopus 로고
    • Regulation of immunity to parasites by T cells and T cell-derived cytokines
    • Sher, A., and R.L. Coffman. 1992. Regulation of immunity to parasites by T cells and T cell-derived cytokines. Annu. Rev. Immunol. 10:385-409.
    • (1992) Annu. Rev. Immunol. , vol.10 , pp. 385-409
    • Sher, A.1    Coffman, R.L.2
  • 21
    • 0030746897 scopus 로고    scopus 로고
    • Th1-Th2: Reliable paradigm or dangerous dogma?
    • Allen, J.E., and R.M. Maizels. 1997. Th1-Th2: reliable paradigm or dangerous dogma? Immunol. Today. 18:387-392.
    • (1997) Immunol. Today , vol.18 , pp. 387-392
    • Allen, J.E.1    Maizels, R.M.2
  • 22
    • 0032550353 scopus 로고    scopus 로고
    • T helper 1 (Th1) and Th2 characteristics start to develop during T cell priming and are associated with an immediate ability to induce immunoglobulin class switching
    • Toellner, K.M., S.A. Luther, D. Sze, R. Choy, D.R. Taylor, I. MacLennan, and H. Acha-Orbea. 1998. T helper 1 (Th1) and Th2 characteristics start to develop during T cell priming and are associated with an immediate ability to induce immunoglobulin class switching. J. Exp. Med. 187:1193-1204.
    • (1998) J. Exp. Med. , vol.187 , pp. 1193-1204
    • Toellner, K.M.1    Luther, S.A.2    Sze, D.3    Choy, R.4    Taylor, D.R.5    MacLennan, I.6    Acha-Orbea, H.7
  • 24
    • 0028981128 scopus 로고
    • Interleukin-4 enhances interferon-gamma synthesis but inhibits development of interferon-gamma-producing cells
    • Noble, A., and D.M. Kemeny. 1995. Interleukin-4 enhances interferon-gamma synthesis but inhibits development of interferon-gamma-producing cells. Immunology. 85:357-363.
    • (1995) Immunology , vol.85 , pp. 357-363
    • Noble, A.1    Kemeny, D.M.2
  • 25
    • 0027788043 scopus 로고
    • The relationship of IL-4- and IFN gamma-producing T cells studied by lineage ablation of IL-4-producing cells
    • Kamogawa, Y., L.A. Minasi, S.R. Carding, K. Bottomly, and R.A. Flavell. 1993. The relationship of IL-4- and IFN gamma-producing T cells studied by lineage ablation of IL-4-producing cells. Cell. 75:985-995.
    • (1993) Cell , vol.75 , pp. 985-995
    • Kamogawa, Y.1    Minasi, L.A.2    Carding, S.R.3    Bottomly, K.4    Flavell, R.A.5
  • 26
    • 0030298210 scopus 로고    scopus 로고
    • Efficient targeting of the IL-4 gene in a BALB/c embryonic stem cell line
    • Noben-Trauth, N., G. Köhler, K. Burki, and B. Ledermann. 1996. Efficient targeting of the IL-4 gene in a BALB/c embryonic stem cell line. Transgenic Res. 5:487-491.
    • (1996) Transgenic Res. , vol.5 , pp. 487-491
    • Noben-Trauth, N.1    Köhler, G.2    Burki, K.3    Ledermann, B.4
  • 27
    • 0030023112 scopus 로고    scopus 로고
    • Susceptibility to Leishmania major infection in interleukin-4-deficient mice
    • Noben-Trauth, N., P. Kropf, and I. Müller. 1996. Susceptibility to Leishmania major infection in interleukin-4-deficient mice. Science. 271:987-990.
    • (1996) Science , vol.271 , pp. 987-990
    • Noben-Trauth, N.1    Kropf, P.2    Müller, I.3
  • 28
    • 0021077888 scopus 로고
    • TS/A: A new metastasizing cell line from a BALB/c spontaneous mammary adenocarcinoma
    • Nanni, P., C. de Giovanni, P.L. Lollini, G. Nicoletti, and G. Prodi. 1983. TS/A: a new metastasizing cell line from a BALB/c spontaneous mammary adenocarcinoma. Clin. Exp. Metastasis. 1:373-380.
    • (1983) Clin. Exp. Metastasis , vol.1 , pp. 373-380
    • Nanni, P.1    De Giovanni, C.2    Lollini, P.L.3    Nicoletti, G.4    Prodi, G.5
  • 29
    • 0016696542 scopus 로고
    • Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure
    • Corbett, T.H., D.J. Griswold, B.J. Roberts, J.C. Peckham, and F.J. Schabel. 1975. Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure. Cancer Res. 35:2434-2439.
    • (1975) Cancer Res. , vol.35 , pp. 2434-2439
    • Corbett, T.H.1    Griswold, D.J.2    Roberts, B.J.3    Peckham, J.C.4    Schabel, F.J.5
  • 30
    • 0024547146 scopus 로고
    • Derivation of a T cell line that is highly responsive to IL-4 and IL-2 (CT.4R) and of an IL-2 hyporesponsive mutant of that line (CT.4S)
    • Hu, L.J., J. Ohara, C. Watson, W. Tsang, and W.E. Paul. 1989. Derivation of a T cell line that is highly responsive to IL-4 and IL-2 (CT.4R) and of an IL-2 hyporesponsive mutant of that line (CT.4S).J. Immunol. 142:800-807.
    • (1989) J. Immunol. , vol.142 , pp. 800-807
    • Hu, L.J.1    Ohara, J.2    Watson, C.3    Tsang, W.4    Paul, W.E.5
  • 31
    • 0016792586 scopus 로고
    • Genetic variation of in vitro cytolytic activity and in vivo rejection potential of non-immunized semi-syngeneic mice against a mouse lymphoma line
    • Kiessling, R., G. Petranyi, G. Klein, and H. Wigzel. 1975. Genetic variation of in vitro cytolytic activity and in vivo rejection potential of non-immunized semi-syngeneic mice against a mouse lymphoma line. Int. J. Cancer. 15:933-940.
    • (1975) Int. J. Cancer , vol.15 , pp. 933-940
    • Kiessling, R.1    Petranyi, G.2    Klein, G.3    Wigzel, H.4
  • 33
    • 0029885750 scopus 로고    scopus 로고
    • IL-12 is an effective adjuvant to recombinant vaccinia virus-based tumor vaccines: Enhancement by simultaneous B7-1 expression
    • Rao, J.B., R.S. Chamberlain, V. Bronte, M.W. Carroll, K.R. Irvine, B. Moss, S.A. Rosenberg, and N.P. Restifo. 1996. IL-12 is an effective adjuvant to recombinant vaccinia virus-based tumor vaccines: enhancement by simultaneous B7-1 expression. J. Immunol. 156:3357-3365.
    • (1996) J. Immunol. , vol.156 , pp. 3357-3365
    • Rao, J.B.1    Chamberlain, R.S.2    Bronte, V.3    Carroll, M.W.4    Irvine, K.R.5    Moss, B.6    Rosenberg, S.A.7    Restifo, N.P.8
  • 39
    • 0028500836 scopus 로고
    • Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFN gamma receptors
    • Dighe, A.S., E. Richards, L.J. Old, and R.D. Schreiber. 1994. Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFN gamma receptors. Immunity. 1:447-456.
    • (1994) Immunity , vol.1 , pp. 447-456
    • Dighe, A.S.1    Richards, E.2    Old, L.J.3    Schreiber, R.D.4
  • 41
    • 0031930938 scopus 로고    scopus 로고
    • Neutrophils but not eosinophils are involved in growth suppression of IL-4-secreting tumors
    • Noffz, G., Z. Qin, M. Kopf, and T. Blankenstein. 1998. Neutrophils but not eosinophils are involved in growth suppression of IL-4-secreting tumors. J. Immunol. 160:345-350.
    • (1998) J. Immunol. , vol.160 , pp. 345-350
    • Noffz, G.1    Qin, Z.2    Kopf, M.3    Blankenstein, T.4
  • 42
    • 0031570843 scopus 로고    scopus 로고
    • Interleukin-10 prevents dendritic cell accumulation and vaccination with granulocyte-macrophage colony-stimulating factor gene-modified tumor cells
    • Qin, Z., G. Noffz, M. Mohaupt, and T. Blankenstein. 1997. Interleukin-10 prevents dendritic cell accumulation and vaccination with granulocyte-macrophage colony-stimulating factor gene-modified tumor cells. J. Immunol. 159:770-776.
    • (1997) J. Immunol. , vol.159 , pp. 770-776
    • Qin, Z.1    Noffz, G.2    Mohaupt, M.3    Blankenstein, T.4
  • 43
    • 2642622573 scopus 로고    scopus 로고
    • Interleukin 4 gene-defective mice reconstituted with wild-type bone marrow fail to produce normal immunoglobulin E levels
    • Lange, C., T. Schüler, and T. Blankenstein. 1998. Interleukin 4 gene-defective mice reconstituted with wild-type bone marrow fail to produce normal immunoglobulin E levels. J. Exp. Med. 187:1487-1493.
    • (1998) J. Exp. Med. , vol.187 , pp. 1487-1493
    • Lange, C.1    Schüler, T.2    Blankenstein, T.3
  • 44
    • 0025119692 scopus 로고
    • Low doses of IL-4 injected perilymphatically in tumor-bearing mice inhibit the growth of poorly and apparently nonimmunogenic tumors and in-duce a tumor-specific immune memory
    • Bosco, M., M. Giovarelli, M. Forni, A. Modesti, S. Scarpa, L. Masuelli, and G. Forni. 1990. Low doses of IL-4 injected perilymphatically in tumor-bearing mice inhibit the growth of poorly and apparently nonimmunogenic tumors and in-duce a tumor-specific immune memory. J. Immunol. 145: 3136-3143.
    • (1990) J. Immunol. , vol.145 , pp. 3136-3143
    • Bosco, M.1    Giovarelli, M.2    Forni, M.3    Modesti, A.4    Scarpa, S.5    Masuelli, L.6    Forni, G.7
  • 45
    • 0032007351 scopus 로고    scopus 로고
    • IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis
    • Urban, J., N. Noben-Trauth, D.D. Donaldson, K.B. Madden, S.C. Morris, M. Collins, and F.D. Finkelman. 1998. IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis. Immunity. 8:255-264.
    • (1998) Immunity , vol.8 , pp. 255-264
    • Urban, J.1    Noben-Trauth, N.2    Donaldson, D.D.3    Madden, K.B.4    Morris, S.C.5    Collins, M.6    Finkelman, F.D.7
  • 46
    • 0032554784 scopus 로고    scopus 로고
    • Differences between IL-4R alpha-deficient and IL-4-deficient mice reveal a role for IL-13 in the regulation of Th2 responses
    • Barner, M., M. Mohrs, F. Brombacher, and M. Kopf. 1998. Differences between IL-4R alpha-deficient and IL-4-deficient mice reveal a role for IL-13 in the regulation of Th2 responses. Curr. Biol. 8:669-672.
    • (1998) Curr. Biol. , vol.8 , pp. 669-672
    • Barner, M.1    Mohrs, M.2    Brombacher, F.3    Kopf, M.4
  • 47
    • 0027930810 scopus 로고
    • The immune response to Plasmodium chabaudi malaria in interleukin-4-deficient mice
    • von der Weid, T., M. Kopf, G. Köhler, and J. Langhorne. 1994. The immune response to Plasmodium chabaudi malaria in interleukin-4-deficient mice. Eur. J. Immunol. 24:2285-2293.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2285-2293
    • Von Der Weid, T.1    Kopf, M.2    Köhler, G.3    Langhorne, J.4
  • 48
    • 0027367189 scopus 로고
    • Resistance of mice deficient in IL-4 to retrovirus-induced immunodeficiency syndrome (MAIDS)
    • Kanagawa, O., B.A. Vaupel, S. Gayama, G. Koehler, and M. Kopf. 1993. Resistance of mice deficient in IL-4 to retrovirus-induced immunodeficiency syndrome (MAIDS). Science. 262:240-242.
    • (1993) Science , vol.262 , pp. 240-242
    • Kanagawa, O.1    Vaupel, B.A.2    Gayama, S.3    Koehler, G.4    Kopf, M.5


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