Altered ligands reveal limited plasticity in the T cell response to a pathogenic epitope

Journal of Experimental Medicine

Volumn 189, Issue 7, 1999, Pages 1111-1120

  Pingel, Sabine ^a   Launois, Pascal ^a,b   Fowell, Deborah J ^a   Turck, Christoph W ^a   Southwood, Scott ^c   Sette, Alessandro ^c   Glaichenhaus, Nicolas ^d   Louis, Jacques A ^b   Locksley, Richard M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c CYTEL CORPORATION   (United States)

^d INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Altered peptide ligands; CD4+ T cell subsets; LACK antigen; Leishmania major

Indexed keywords

INTERLEUKIN 4;

ANTIGEN SPECIFICITY; ARTICLE; CELL DIFFERENTIATION; EFFECTOR CELL; EPITOPE MAPPING; GENE DELETION; HELPER CELL; IMMUNE RESPONSE; INFECTION; LEISHMANIA MAJOR; LEISHMANIASIS; LIGAND BINDING; MACROPHAGE ACTIVATION; NERVE CELL PLASTICITY; PRIORITY JOURNAL; RECEPTOR AFFINITY; T LYMPHOCYTE ACTIVATION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ANTIGENS, PROTOZOAN; DISEASE SUSCEPTIBILITY; EPITOPES; FEMALE; HISTOCOMPATIBILITY ANTIGENS CLASS II; IMMUNE TOLERANCE; IMMUNITY, CELLULAR; INTERFERON TYPE II; INTERLEUKIN-4; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; LIGANDS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTOZOAN PROTEINS; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECOMBINANT FUSION PROTEINS; SUPERANTIGENS; TH2 CELLS;

EID: 0033526022     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.189.7.1111     Document Type: Article

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