Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response

European Journal of Immunology

Volumn 26, Issue 7, 1996, Pages 1553-1559

  Mattner, Frank ^a   Magram, Jeanne ^b   Ferrante, Jessica ^b   Launois, Pascal ^c   Padova, Karin Di ^a   Behin, Reza ^c   Gately, Maurice K ^b   Louis, Jacques A ^c   Alber, Gottfried ^a,d  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b HOFFMANN LA ROCHE INC   (United States)

^c UNIVERSITY OF LAUSANNE   (Switzerland)

^d UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Interleukin 12 deficient mice; Leishmania major; Th1 Th2 differentiation

Indexed keywords

CD4 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 4; MESSENGER RNA;

ANIMAL EXPERIMENT; ARTICLE; CELLULAR IMMUNITY; DELAYED HYPERSENSITIVITY; FEMALE; GENE DISRUPTION; HELPER CELL; INFECTION RESISTANCE; INFECTION SENSITIVITY; LEISHMANIA MAJOR; LEISHMANIASIS; MOUSE; NONHUMAN; PARASITE IMMUNITY; PRIORITY JOURNAL;

ANIMALS; ANIMALS, NEWBORN; CD4-POSITIVE T-LYMPHOCYTES; DISEASE SUSCEPTIBILITY; FEMALE; IMMUNITY, NATURAL; INTERLEUKIN-12; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; TH2 CELLS;

EID: 0030002111     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.1830260722     Document Type: Article

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