Serial backross mapping of multiple loci associated with resistance to leishmania major in mice

Immunity

Volumn 6, Issue 5, 1997, Pages 551-557

  Beebe, Amy M ^a   Mauze, Smita ^a   Schork, Nicholas J ^b,c,d   Coffman, Robert L ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d JACKSON LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GENE MAPPING; HELPER CELL; HOST RESISTANCE; LEISHMANIA MAJOR; LEISHMANIASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CHROMOSOME MAP; CROSS BREEDING; DISEASE PREDISPOSITION; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETICS; GENOTYPE; IMMUNOLOGY; INNATE IMMUNITY; MALE; PEDIGREE; PHENOTYPE; PROBABILITY; SKIN LEISHMANIASIS;

ANIMALS; CHROMOSOME MAPPING; CROSSES, GENETIC; DISEASE SUSCEPTIBILITY; FEMALE; GENOTYPE; IMMUNITY, NATURAL; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; LINKAGE DISEQUILIBRIUM; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PEDIGREE; PHENOTYPE; PROBABILITY;

EID: 0030612781     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80343-X     Document Type: Article

References (26)

1. Bartlett, M.S., and Haldane, J.B.S. (1935). The theory of inbreeding with forced heterozygosity. J. Genet. 31, 327-340.
2. Belosevic, M., Finbloom, D.S., Van Der Meide, P.M., Slayter, M.V., and Nacy, C.A. (1989). Administration of monoclonal anti-IFN-gamma antibodies in vivo abrogates natural resistance of C3H/HeN mice to infection with Leishmania major. J. Immunol. 143, 266-274.
3. Blackwell, J.M., Hale, C., Roberts, M.B., Ulczak, O.M., Liew, F.Y., and Howard, J.G. (1985). An H-11-linked gene has a parallel effect on Leishmania major and L. donovani infections in mice. Immunogenetics 21, 385-395.
4. Brownstein, D.G., Bhatt, P.N., Gras, L., and Budris, T. (1992). Serial backcross analysis of genetic resistance to mousepox, using marker loci for Rmp-2 and Rmp-3. J. Virol. 66, 7073-7079.
5. Chatelain, R., Varkila, K., and Coffman, R.L. (1992). IL-4 induces a Th2 response in Leishmania-major-infected Mice. J. Immunol. 148, 1182-1187.
6. Chen, S.Z., and Evans, G.A. (1990). A simple screening method for transgenic mice using the polymerase chain reaction. Biotechniques 8, 32-33.
7. DeTolla, L.J., Scott, P.A., and Farrell, J.P. (1981). Single gene control of resistance to cutaneous leishmaniasis in mice. Immunogenetics 14, 29-39.
8. Fisher, R.A. (1965). The Theory of Inbreeding, second edition (Edinburgh: Oliver and Boyd).
9. Giannini, M.S. (1986). Sex-influenced response in the pathogenesis of cutaneous leishmaniasis in mice. Parasite Immunol. 8, 31-37.
10. Gorham, J.D., Guler, M.L., Steen, R.G., Mackey, A.J., Daly, M.J., Frederick, K., Dietrich, W.F., and Murphy, K.M. (1996). Genetic mapping of a murine locus controlling development of T helper 1/T helper 2 type responses. Proc. Natl. Acad. Sci. USA 93, 12467-12472.
11. Heinzel, F.P., Sadick, M.D., Holaday, B.J., Coffman, R.L., and Locksley, R.M. (1989). Reciprocal expression of interferon gamma or IL4 during the resolution or progression of murine leishmaniasis: evidence for expansion of distinct helper T cell subsets. J. Exp. Med. 169, 59-72.
12. Heinzel, F.P., Schoenhaut, D.S., Rerko, R.M., Rosser, L.E., and Gately, M.K. (1993). Recombinant interleukin 12 cures mice infected with Leishmania major. J. Exp. Med. 177, 1505-1509.
13. Howard, J.G., Hale, C., and Chan-Liew, W.L. (1980a). Immunological regulation of experimental cutaneous leishmaniasis. I. Immunogenetic aspects of susceptibility to Leishmania tropica in mice. Parasite Immunol. 2, 303-314.
14. Howard, J.G., Hale, C., and Liew, F.Y. (1980b). Genetically determined susceptibility to Leishmania tropica infection is expressed by hemopoietic donor cells in mouse radiation chimeras. Nature 288, 161-162.
15. Karlin, S., and Liberman, U. (1979). A natural class of multilocus recombination processes and related measures of crossover interference. Adv. Appl. Probability 11, 479-501.
16. Krishnan, L., Guilbert, L.J., Russell, A.S., Wegmann, T.G., Mosmann, T.R., and Belosevic, M. (1996). Pregnancy impairs resistance of C57BL/6 mice to Leishmania major infection and causes decreased antigen-specific IFN-gamma response and increased production of T helper 2 cytokines. J. Immunol. 156, 644-652.
17. Lander, E., and Kruglyak, L. (1995). Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat. Genet. 11, 241-247.
18. Liew, F.Y., and O'Donnell, C.A. (1993). Immunology of leishmaniasis. Adv. Parasitol. 32, 161-259.
19. Mock, B., Blackwell, J., Hilgers, J., Potter, M., and Nacy, C. (1993). Genetic control of Leishmania major infection in congenic, recombinant inbred and F2 populations of mice. Eur. J. Immunogenet. 20, 335-348.
20. Mosmann, T.R., and Coffman, R.L. (1989). TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7, 145-173.
21. Murray, H.W. (1994). Interferon-gamma and host antimicrobial defense: current and future clinical applications. Am. J. Med. 97, 459-467.
22. Reiner, S.L., and Locksley, R.M. (1995). The regulation of immunity to Leishmania major. Annu. Rev. Immunol. 13, 151-177.
23. Roberts, M., Mock, B.A., and Blackwell, J.M. (1993). Mapping of genes controlling Leishmania major infection in CXS recombinant mice. Eur. J. Immunogenet. 20, 349-362.
24. Sadick, M.D., Heinzel, F.P., Holaday, B.J., Pu, R.T., Dawkins, R.S., and Locksley, R.M. (1990). Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody: evidence for a T cell-dependent, interferon gamma-independent mechanism. J. Exp. Med. 171, 115-127.
25. Spielman, R.S., McGinnis, R.E., and Ewens, W.J. (1993). Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am. J. Hum. Genet. 52, 506-516.
26. Sypek, J.P., Chung, C.L., Mayor, S.E., Subramanyam, J.M., Goldman, S.J., Sieburth, D.S., Wolf, S.F., and Schaub, R.G. (1993). Resolution of cutaneous leishmaniasis: interleukin 12 initiates a protective T helper type 1 immune response. J. Exp. Med. 177, 1797-1802.