Rapid expansion and IL-4 expression by Leishmania-specific naive helper T cells in vivo

Immunity

Volumn 17, Issue 2, 2002, Pages 191-200

  Stetson, Daniel B ^a   Mohrs, Markus ^a   Mallet Designe, Valerie ^b   Teyton, Luc ^b   Locksley, Richard M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 4;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; HELPER CELL; IN VIVO STUDY; INFECTION RESISTANCE; INFECTION SENSITIVITY; LEISHMANIA MAJOR; LEISHMANIASIS; LYMPH NODE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0036669784     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(02)00363-1     Document Type: Article

References (43)

1. Biedermann T., Zimmermann S., Himmelrich H., Gumy A., Egeter O., Sakrauski A.K., Seegmuller I., Voight H., Launois P., Levine A.D.et al. IL-4 instructs Th1 responses and resistance to Leishmania major in susceptible BALB/c mice. Nat. Immunol. 2:2001;1054-1060.
2. Blattman J.N., Antia R., Sourdive D.J.D., Wang X., Kaech S.M., Murali-Krishna K., Altman J.D., Ahmed R. Estimating the precursor frequency of naive antigen-specific CD8 T cells. J. Exp. Med. 195:2002;657-664.
3. Brown D.R., Fowell D.J., Corry D.B., Wynn T.A., Moskowitz N.H., Cheever A.W., Locksley R.M., Reiner S.L. β2-microglobulin-dependent NK1.1 T cells are not essential for T helper cell 2 immune responses. J. Exp. Med. 184:1996;1295-1304.
4. Casrouge A., Beaudoing E., Dalle S., Pannetier C., Kanellopoulos J., Kourilsky P. Size estimate of the alpha beta TCR repertoire of naive mouse splenocytes. J. Immunol. 164:2000;5782-5787.
5. Fahmy T.M., Glick Bieler J., Edidin M., Schneck J.P. Increased TCR avidity after T cell activation. a mechanism for sensing low-density antigen Immunity. 14:2001;135-143.
6. + T cells. Immunity. 11:1999;399-409.
7. Garside P., Ingulli E., Merica R.R., Johnson J.G., Noelle R.J., Jenkins M.K. Visualization of specific B and T lymphocyte interactions in the lymph node. Science. 281:1998;96-99.
8. Grogan J.L., Mohrs M., Harmon B., Lacy D.A., Sedat J.W., Locksley R.M. Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets. Immunity. 14:2001;205-215.
9. Hochrein H., O'Keefe M., Luft T., Vandenabeele S., Grumont R.J., Maraskovsky E., Shortman K. Interleukin (IL)-4 is a major regulatory cytokine governing bioactive IL-12 production by mouse and human dendritic cells. J. Exp. Med. 192:2000;823-833.
10. Hsieh C.-S., Macatonia S.E., Tripp C.S., Wolf S.F., O'Garra A., Murphy K.M. Development of Th1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages. Science. 260:1993;547-549.
11. Huang Q., Liu D., Majewski P., Schulte L.C., Korn J.M., Young R.A., Lander E.S., Hacohen N. The plasticity of dendritic cell responses to pathogens and their components. Science. 294:2001;870-875.
12. Julia V., Rassoulzadegan R., Glaichenhaus N. Resistance to Leishmania major induced by tolerance to a single antigen. Science. 274:1996;421-423.
13. Julia V., McSorley S.S., Malherbe L., Breittmayer J.P., Girard-Pipau F., Beck A., Glaichenhaus N. Priming by microbial antigens from the intestinal flora determines the ability of CD4+ T cells to rapidly secrete IL-4 in BALB/c mice infected with Leishmania major. J. Immunol. 165:2000;5637-5645.
14. Laskay T., Diefenbach A., Rollinghoff M., Solbach W. Early parasite containment is decisive for resistance to Leishmania major infection. Eur. J. Immunol. 25:1995;2220-2227.
15. + T cells instructs Th2 development and susceptibility of BALB/c mice. Immunity. 6:1997;541-549.
16. Liu Y.-J., Kanzler H., Soumelis V., Gilliet M. Dendritic cell lineage, plasticity and cross-regulation. Nat. Immunol. 2:2001;585-589.
17. + T cells in resistant mice upon infection with Leishmania major. Immunity. 13:2000;771-782.
18. Matsuda J.L., Naidenko O.V., Gapin L., Nakayama T., Taniguchi M., Wang C.-R., Koezuka Y., Kronenberg M. Tracking the response of natural killer T cells by a glycolipid antigen using CD1d tetramers. J. Exp. Med. 192:2000;741-753.
19. McHeyzer-Williams M.G., Davis M.M. Antigen-specific development of primary and memory T cells in vivo. Science. 268:1995;106-111.
20. McHeyzer-Williams L.J., Panus J.F., Mikszta J.A., McHeyzer-Williams M.G. Evolution of antigen-specific T cell receptors in vivo. preimmune and antigen-driven selection of preferred complementarity determining region 3 (CDR3) motifs J. Exp. Med. 189:1999;1823-1838.
21. Mohrs M., Shinkai K., Mohrs K., Locksley R.M. Analysis of type 2 immunity in vivo using a bicistronic IL-4 reporter. Immunity. 15:2001;301-311.
22. Morris L., Troutt A.B., Handman E., Kelso A. Changes in the precursor frequencies of IL-4 and IFN-γ secreting CD4+ cells correlate with resolution of lesions in murine cutaneous leishmaniasis. J. Immunol. 149:1992;2715-2721.
23. Mougneau E., Altare F., Wakil A.E., Zheng S., Coppola T., Wang Z.E., Waldmann R., Locksley R.M., Glaichenhaus N. Expression cloning of a protective Leishmania antigen. Science. 268:1995;563-566.
24. Murphy K.M., Heimberger A.B., Loh D.Y. Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo. Science. 250:1990;1720-1723.
25. Noben-Trauth N., Kropf P., Muller I. Susceptibility to Leishmania major infection in interleukin-4-deficient mice. Science. 271:1996;987-990.
26. Panus J.F., McHeyzer-Williams L.J., McHeyzer-Williams M.G. Antigen-specific T helper cell function. differential cytokine expression in primary and memory responses J. Exp. Med. 192:2000;1301-1316.
27. Pingel S., Launois P., Fowell D.J., Turck C.W., Southwood S., Sette A., Glaichenhaus N., Louis J.A., Locksley R.M. Altered ligands reveal limited plasticity in the T cell response to a pathogenic epitope. J. Exp. Med. 189:1999;1111-1120.
28. Prina E., Lang T., Glaichenhaus N., Antoine J.-C. Presentation of the protective parasite antigen LACK by Leishmania-infected macrophages. J. Immunol. 156:1996;4318-4327.
29. Reiner S.L., Locksley R.M. The regulation of immunity to Leishmania major. Annu. Rev. Immunol. 13:1995;151-177.
30. Reiner S.L., Zheng S., Wang Z.E., Stowring L., Locksley R.M. Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection. J. Exp. Med. 179:1994;447-456.
31. Reiner S.L., Fowell D.J., Moskowitz N.H., Swier K., Brown D.R., Brown C.R., Turck C.W., Scott P.A., Killeen N., Locksley R.M. Control of Leishmania major by a monoclonal αβ T cell repertoire. J. Immunol. 160:1998;884-889.
32. Reinhardt R.L., Khoruts A., Merica R., Zell T., Jenkins M.K. Visualizing the generation of memory T cells in the whole body. Nature. 410:2001;101-105.
33. Reis e Sousa C. Dendritic cells as sensors of infection. Immunity. 14:2001;495-498.
34. Rissoan M.-C., Soumelis V., Kadowaki N., Grouard G., Briere F., de Waal Malefyt R., Liu Y.J. Reciprocal control of T helper cell and dendritic cell differentiation. Science. 283:1999;1183-1186.
35. Sadick M.D., Street N., Mosmann T.R., Locksley R.M. Cytokine regulation of murine leishmaniasis. interleukin 4 is not sufficient to mediate progressive disease in resistant C57BL/6 mice Infect. Immun. 59:1991;4710-4714.
36. Schatz P.J. Use of peptide libraries to map the substrate specificity of a peptide-modifying enzyme. a 13 residue consensus peptide specifies biotinylation in Escherichia coli Biotechnology. 11:1993;1138-1143.
37. Schnare M., Barton G.M., Holt A.C., Takeda K., Akira S., Medzhitov R. Toll-like receptors control activation of adaptive immune responses. Nat. Immunol. 2:2001;947-950.
38. Schuler T., Qin Z., Noben-Trauth N., Blankenstein T. T helper cell type 1-associated and cytotoxic T lymphocyte-mediated tumor immunity is impaired in interleukin 4-deficient mice. J. Exp. Med. 189:1999;803-810.
39. Schuler T., Kammertoens T., Preiss S., Debs P., Noben-Trauth N., Blankenstein T. Generation of tumor-associated cytotoxic T lymphocytes requires interleukin 4 from CD8(+) T cells. J. Exp. Med. 194:2001;767-775.
40. d Protein Sci. 7:1998;413-418.
41. Sommer F., Meixner M., Mannherz M., Ogilvie A.L.J., Rollinghoff M., Lohoff M. Analysis of cytokine patterns produced by individual CD4+ lymph node cells during experimental murine leishmaniasis in resistant and susceptible mice. Int. Immunol. 10:1998;1853-1861.
42. Topham D., Doherty P.C. Longitudinal analysis of the acute sendai virus-specific CD4+ T cell response and memory. J. Immunol. 161:1998;4530-4535.
43. Whitmire J.K., Asano M.S., Murali-Krishna K., Suresh M., Ahmed R. Long-term CD4 Th1 and Th2 memory following acute lymphocyte choriomeningitis virus infection. J. Virol. 72:1998;8281-8288.