-
1
-
-
0028838971
-
Protein kinases and phosphatases: The yin and yang of protein phosphorylation and signaling
-
Hunter T. 1995. Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling. Cell 80:225-36
-
(1995)
Cell
, vol.80
, pp. 225-236
-
-
Hunter, T.1
-
2
-
-
0035895505
-
The sequence of the human genome
-
Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, et al. 2001. The sequence of the human genome. Science 291:1304-51
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
Li, P.W.4
Mural, R.J.5
-
3
-
-
2942581416
-
Protein tyrosine phosphatases in the human genome
-
Alonso A, Sasin J, Bottini N, Friedberg I, Friedberg I, et al. 2004. Protein tyrosine phosphatases in the human genome. Cell 117:699-711
-
(2004)
Cell
, vol.117
, pp. 699-711
-
-
Alonso, A.1
Sasin, J.2
Bottini, N.3
Friedberg, I.4
Friedberg, I.5
-
5
-
-
0036181649
-
Protein tyrosine phosphatases: Structure and function, substrate specificity, and inhibitor development
-
Zhang ZY. 2002. Protein tyrosine phosphatases: structure and function, substrate specificity, and inhibitor development. Annu. Rev. Pharmacol. Toxicol. 42:209-34
-
(2002)
Annu. Rev. Pharmacol. Toxicol.
, vol.42
, pp. 209-234
-
-
Zhang, Z.Y.1
-
6
-
-
0029975476
-
Crystal structure of the dual specificity protein phosphatase VHR
-
Yuvaniyama J, Denu JM, Dixon JE, Saper MA. 1996. Crystal structure of the dual specificity protein phosphatase VHR. Science 272:1328-31
-
(1996)
Science
, vol.272
, pp. 1328-1331
-
-
Yuvaniyama, J.1
Denu, J.M.2
Dixon, J.E.3
Saper, M.A.4
-
7
-
-
0038339419
-
Genomic analysis of the eukaryotic protein kinase superfamily: A perspective
-
111.1-7
-
Hanks SK. 2003. Genomic analysis of the eukaryotic protein kinase superfamily: a perspective. Genome Biol. 4:111.1-7
-
(2003)
Genome Biol.
, vol.4
-
-
Hanks, S.K.1
-
8
-
-
0026569665
-
The cdc25 M-phase inducer: An unconventional protein phosphatase
-
Millar JB, Russell P. 1992. The cdc25 M-phase inducer: an unconventional protein phosphatase. Cell 68:407-10
-
(1992)
Cell
, vol.68
, pp. 407-410
-
-
Millar, J.B.1
Russell, P.2
-
9
-
-
0026970108
-
The cell cycle regulator, human p50weel, is a tyrosine kinase and not a serine/tyrosine kinase
-
Honda R, Ohba Y, Yasuda H. 1992. The cell cycle regulator, human p50weel, is a tyrosine kinase and not a serine/tyrosine kinase. Biochem. Biophys. Res. Commun. 186:1333-38
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.186
, pp. 1333-1338
-
-
Honda, R.1
Ohba, Y.2
Yasuda, H.3
-
10
-
-
0031053117
-
The human Myt1 kinase preferentially phosphorylates Cdc2 on threonine 14 and localizes to the endoplasmic reticulum and Golgi complex
-
Liu F, Stanton JJ, Wu Z, Piwnica-Worms H. 1997. The human Myt1 kinase preferentially phosphorylates Cdc2 on threonine 14 and localizes to the endoplasmic reticulum and Golgi complex. Mol. Cell Biol. 17:571-83
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 571-583
-
-
Liu, F.1
Stanton, J.J.2
Wu, Z.3
Piwnica-Worms, H.4
-
11
-
-
0034162636
-
Preclinical and clinical development of cyclin-dependent kinase modulators
-
Senderowicz AM, Sausville EA. 2000. Preclinical and clinical development of cyclin-dependent kinase modulators. J. Natl. Cancer Inst. 92:376-87
-
(2000)
J. Natl. Cancer Inst.
, vol.92
, pp. 376-387
-
-
Senderowicz, A.M.1
Sausville, E.A.2
-
12
-
-
0025324692
-
Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2
-
Sadhu K, Reed SI, Richardson H, Russell P. 1990. Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2. Proc. Natl. Acad. Sci. USA 87:5139-43
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 5139-5143
-
-
Sadhu, K.1
Reed, S.I.2
Richardson, H.3
Russell, P.4
-
13
-
-
0028168379
-
Activation of p34cdc2 protein kinase by microinjection of human cdc25C into mammalian cells. Requirement for prior phosphorylation of cdc25C by p34cdc2 on sites phosphorylated at mitosis
-
Strausfeld U, Fernandez A, Capony JP, Girard F, Lautredou N, et al. 1994. Activation of p34cdc2 protein kinase by microinjection of human cdc25C into mammalian cells. Requirement for prior phosphorylation of cdc25C by p34cdc2 on sites phosphorylated at mitosis. J. Biol. Chem. 269:5989-6000
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 5989-6000
-
-
Strausfeld, U.1
Fernandez, A.2
Capony, J.P.3
Girard, F.4
Lautredou, N.5
-
14
-
-
0025917804
-
p55CDC25 is a nuclear protein required for the initiation of mitosis in human cells
-
Millar JB, Blevitt J, Gerace L, Sadhu K, Featherstone C, Russell P. 1991. p55CDC25 is a nuclear protein required for the initiation of mitosis in human cells. Proc. Natl. Acad. Sci. USA 88:10500-4
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 10500-10504
-
-
Millar, J.B.1
Blevitt, J.2
Gerace, L.3
Sadhu, K.4
Featherstone, C.5
Russell, P.6
-
15
-
-
0027339731
-
Dephosphorylation of human p34cdc2 kinase on both Thr-14 and Tyr-15 by human cdc25B phosphatase
-
Honda R, Ohba Y, Nagata A, Okayama H, Yasuda H. 1993. Dephosphorylation of human p34cdc2 kinase on both Thr-14 and Tyr-15 by human cdc25B phosphatase. FEBS Lett. 318:331-34
-
(1993)
FEBS Lett.
, vol.318
, pp. 331-334
-
-
Honda, R.1
Ohba, Y.2
Nagata, A.3
Okayama, H.4
Yasuda, H.5
-
16
-
-
0031669731
-
The cdc25B phosphatase is essential for the G2/M phase transition in human cells
-
Lammer C, Wagerer S, Saffrich R, Mertens D, Ansorge W, Hoffmann I. 1998. The cdc25B phosphatase is essential for the G2/M phase transition in human cells. J. Cell Sci. 111(Pt. 16):2445-53
-
(1998)
J. Cell Sci.
, vol.111
, Issue.PART 16
, pp. 2445-2453
-
-
Lammer, C.1
Wagerer, S.2
Saffrich, R.3
Mertens, D.4
Ansorge, W.5
Hoffmann, I.6
-
17
-
-
0031466961
-
Phosphorylation of human CDC25B phosphatase by CDK1-cyclin A triggers its proteasome-dependent degradation
-
Baldin V, Cans C, Knibiehler M, Ducommun B. 1997. Phosphorylation of human CDC25B phosphatase by CDK1-cyclin A triggers its proteasome-dependent degradation. J. Biol. Chem. 272:32731-34
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 32731-32734
-
-
Baldin, V.1
Cans, C.2
Knibiehler, M.3
Ducommun, B.4
-
18
-
-
0029937532
-
Cytoplasmic accumulation of cdc25B phosphatase in mitosis triggers centrosomal microtubule nucleation in HeLa cells
-
Gabrielli BG, De Souza CP, Tonks ID, Clark JM, Hayward NK, Ellem KA. 1996. Cytoplasmic accumulation of cdc25B phosphatase in mitosis triggers centrosomal microtubule nucleation in HeLa cells. J. Cell Sci. 109(Pt. 5):1081-93
-
(1996)
J. Cell Sci.
, vol.109
, Issue.PART 5
, pp. 1081-1093
-
-
Gabrielli, B.G.1
De Souza, C.P.2
Tonks, I.D.3
Clark, J.M.4
Hayward, N.K.5
Ellem, K.A.6
-
19
-
-
0033538847
-
Cdc25B and Cdc25C differ markedly in their properties as initiators of mitosis
-
Karlsson C, Katich S, Hagting A, Hoffmann I, Pines J. 1999. Cdc25B and Cdc25C differ markedly in their properties as initiators of mitosis. J. Cell Biol. 146:573-84
-
(1999)
J. Cell Biol.
, vol.146
, pp. 573-584
-
-
Karlsson, C.1
Katich, S.2
Hagting, A.3
Hoffmann, I.4
Pines, J.5
-
20
-
-
0027471557
-
Cdc25M2 activation of cyclin-dependent kinases by dephosphorylation of threonine-14 and tyrosine-15
-
Sebastian B, Kakizuka A, Hunter T. 1993. Cdc25M2 activation of cyclin-dependent kinases by dephosphorylation of threonine-14 and tyrosine-15. Proc. Natl. Acad. Sci. USA 90:3521-24
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 3521-3524
-
-
Sebastian, B.1
Kakizuka, A.2
Hunter, T.3
-
21
-
-
0030667428
-
Hyperphosphorylation of the N-terminal domain of Cdc25 regulates activity toward cyclin B1/Cdc2 but not cyclin A/Cdk2
-
Gabrielli BG, Clark JM, McCormack AK, Ellem KA. 1997. Hyperphosphorylation of the N-terminal domain of Cdc25 regulates activity toward cyclin B1/Cdc2 but not cyclin A/Cdk2. J. Biol. Chem. 272:28607-14
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 28607-28614
-
-
Gabrielli, B.G.1
Clark, J.M.2
McCormack, A.K.3
Ellem, K.A.4
-
22
-
-
0028022034
-
Activation of the phosphatase activity of human cdc25A by a cdk2-cyclin E dependent phosphorylation at the G1/S transition
-
Hoffmann I, Draetta G, Karsenti E. 1994. Activation of the phosphatase activity of human cdc25A by a cdk2-cyclin E dependent phosphorylation at the G1/S transition. EMBO J. 13:4302-10
-
(1994)
EMBO J.
, vol.13
, pp. 4302-4310
-
-
Hoffmann, I.1
Draetta, G.2
Karsenti, E.3
-
23
-
-
0028314952
-
Cdc25A is a novel phosphatase functioning early in the cell cycle
-
Jinno S, Suto K, Nagata A, Igarashi M, Kanaoka Y, et al. 1994. Cdc25A is a novel phosphatase functioning early in the cell cycle. EMBO J. 13:1549-56
-
(1994)
EMBO J.
, vol.13
, pp. 1549-1556
-
-
Jinno, S.1
Suto, K.2
Nagata, A.3
Igarashi, M.4
Kanaoka, Y.5
-
24
-
-
0032766844
-
Ectopic expression of Cdc25A accelerates the G(1)/S transition and leads to premature activation of cyclin E- and cyclin A-dependent kinases
-
Blomberg I, Hoffmann I. 1999. Ectopic expression of Cdc25A accelerates the G(1)/S transition and leads to premature activation of cyclin E- and cyclin A-dependent kinases. Mol. Cell Biol. 19:6183-94
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 6183-6194
-
-
Blomberg, I.1
Hoffmann, I.2
-
25
-
-
0036847320
-
Regulation of G(2)/M events by Cdc25A through phosphorylation-dependent modulation of its stability
-
Mailand N, Podtelejnikov AV, Groth A, Mann M, Bartek J, Lukas J. 2002. Regulation of G(2)/M events by Cdc25A through phosphorylation-dependent modulation of its stability. EMBO J. 21:5911-20
-
(2002)
EMBO J.
, vol.21
, pp. 5911-5920
-
-
Mailand, N.1
Podtelejnikov, A.V.2
Groth, A.3
Mann, M.4
Bartek, J.5
Lukas, J.6
-
26
-
-
0037119999
-
Dual mode of degradation of Cdc25 A phosphatase
-
Donzelli M, Squatrito M, Ganoth D, Hershko A, Pagano M, Draetta GF. 2002. Dual mode of degradation of Cdc25 A phosphatase. EMBO J. 21:4875-84
-
(2002)
EMBO J.
, vol.21
, pp. 4875-4884
-
-
Donzelli, M.1
Squatrito, M.2
Ganoth, D.3
Hershko, A.4
Pagano, M.5
Draetta, G.F.6
-
27
-
-
0034997233
-
Absence of apparent phenotype in mice lacking Cdc25C protein phosphatase
-
Chen MS, Hurov J, White LS, Woodford-Thomas T, Piwnica-Worms H. 2001. Absence of apparent phenotype in mice lacking Cdc25C protein phosphatase. Mol. Cell Biol. 21:3853-61
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 3853-3861
-
-
Chen, M.S.1
Hurov, J.2
White, L.S.3
Woodford-Thomas, T.4
Piwnica-Worms, H.5
-
28
-
-
0036544855
-
Cdc25b phosphatase is required for resumption of meiosis during oocyte maturation
-
Lincoln AJ, Wickramasinghe D, Stein P, Schultz RM, Palko ME, et al. 2002. Cdc25b phosphatase is required for resumption of meiosis during oocyte maturation. Nat. Genet. 30:446-49
-
(2002)
Nat. Genet.
, vol.30
, pp. 446-449
-
-
Lincoln, A.J.1
Wickramasinghe, D.2
Stein, P.3
Schultz, R.M.4
Palko, M.E.5
-
29
-
-
0035848819
-
The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis
-
Falck J, Mailand N, Syljuasen RG, Bartek J, Lukas J. 2001. The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis. Nature 410:842-47
-
(2001)
Nature
, vol.410
, pp. 842-847
-
-
Falck, J.1
Mailand, N.2
Syljuasen, R.G.3
Bartek, J.4
Lukas, J.5
-
30
-
-
0034717309
-
Rapid destruction of human Cdc25A in response to DNA damage
-
Mailand N, Falck J, Lukas C, Syljuasen RG, Welcker M, et al. 2000. Rapid destruction of human Cdc25A in response to DNA damage. Science 288:1425-29
-
(2000)
Science
, vol.288
, pp. 1425-1429
-
-
Mailand, N.1
Falck, J.2
Lukas, C.3
Syljuasen, R.G.4
Welcker, M.5
-
31
-
-
0037069326
-
Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints
-
Zhao H, Watkins JL, Piwnica-Worms H. 2002. Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints. Proc. Natl. Acad. Sci. USA 99:14795-800
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 14795-14800
-
-
Zhao, H.1
Watkins, J.L.2
Piwnica-Worms, H.3
-
32
-
-
0043066731
-
Regulating mammalian checkpoints through Cdc25 inactivation
-
Donzelli M, Draetta GF. 2003. Regulating mammalian checkpoints through Cdc25 inactivation. EMBO Rep. 4:671-77
-
(2003)
EMBO Rep.
, vol.4
, pp. 671-677
-
-
Donzelli, M.1
Draetta, G.F.2
-
33
-
-
0035969559
-
Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication
-
Nash P, Tang X, Orlicky S, Chen Q, Gertler FB, et al. 2001. Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication. Nature 414:514-21
-
(2001)
Nature
, vol.414
, pp. 514-521
-
-
Nash, P.1
Tang, X.2
Orlicky, S.3
Chen, Q.4
Gertler, F.B.5
-
34
-
-
0042858200
-
Regulation of Cdc25A half-life in interphase by cyclin-dependent kinase 2 activity
-
Ducruet AP, Lazo JS. 2003. Regulation of Cdc25A half-life in interphase by cyclin-dependent kinase 2 activity. J. Biol. Chem. 278:31838-42
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 31838-31842
-
-
Ducruet, A.P.1
Lazo, J.S.2
-
35
-
-
0027509501
-
Phosphorylation and activation of human cdc25-C by cdc2-cyclin B and its involvement in the self-amplification of MPF at mitosis
-
Hoffmann I, Clarke PR, Marcote MJ, Karsenti E, Draetta G. 1993. Phosphorylation and activation of human cdc25-C by cdc2-cyclin B and its involvement in the self-amplification of MPF at mitosis. EMBO J. 12:53-63
-
(1993)
EMBO J.
, vol.12
, pp. 53-63
-
-
Hoffmann, I.1
Clarke, P.R.2
Marcote, M.J.3
Karsenti, E.4
Draetta, G.5
-
36
-
-
0033526819
-
Multiple splicing variants of cdc25B regulate G2/M progression
-
Forrest AR, McCormack AK, DeSouza CP, Sinnamon JM, Tonks ID, et al. 1999. Multiple splicing variants of cdc25B regulate G2/M progression. Biochem. Biophys. Res. Commun. 260:510-15
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.260
, pp. 510-515
-
-
Forrest, A.R.1
McCormack, A.K.2
DeSouza, C.P.3
Sinnamon, J.M.4
Tonks, I.D.5
-
37
-
-
0033646929
-
Alternative splicing in the regulatory region of the human phosphatases CDC25A and CDC25C
-
Wegener S, Hampe W, Herrmann D, Schaller HC. 2000. Alternative splicing in the regulatory region of the human phosphatases CDC25A and CDC25C. Eur. J. Cell Biol. 79:810-15
-
(2000)
Eur. J. Cell Biol.
, vol.79
, pp. 810-815
-
-
Wegener, S.1
Hampe, W.2
Herrmann, D.3
Schaller, H.C.4
-
38
-
-
0035810050
-
Localization of human Cdc25C is regulated both by nuclear export and 14-3-3 protein binding
-
Graves PR, Lovly CM, Uy GL, Piwnica-Worms H. 2001. Localization of human Cdc25C is regulated both by nuclear export and 14-3-3 protein binding. Oncogene 20:1839-51
-
(2001)
Oncogene
, vol.20
, pp. 1839-1851
-
-
Graves, P.R.1
Lovly, C.M.2
Uy, G.L.3
Piwnica-Worms, H.4
-
39
-
-
0030884275
-
A dual-specificity phosphatase Cdc25B is an unstable protein and triggers p34(cdc2)/cyclin B activation in hamster BHK21 cells arrested with hydroxyurea
-
Nishijima H, Nishitani H, Seki T, Nishimoto T. 1997. A dual-specificity phosphatase Cdc25B is an unstable protein and triggers p34(cdc2)/cyclin B activation in hamster BHK21 cells arrested with hydroxyurea. J. Cell Biol. 138:1105-16
-
(1997)
J. Cell Biol.
, vol.138
, pp. 1105-1116
-
-
Nishijima, H.1
Nishitani, H.2
Seki, T.3
Nishimoto, T.4
-
40
-
-
0026234297
-
An additional homolog of the fission yeast cdc25+ gene occurs in humans and is highly expressed in some cancer cells
-
Nagata A, Igarashi M, Jinno S, Suto K, Okayama H. 1991. An additional homolog of the fission yeast cdc25+ gene occurs in humans and is highly expressed in some cancer cells. New Biol. 3:959-68
-
(1991)
New Biol.
, vol.3
, pp. 959-968
-
-
Nagata, A.1
Igarashi, M.2
Jinno, S.3
Suto, K.4
Okayama, H.5
-
41
-
-
0034720268
-
Regulation of CDC25B phosphatases subcellular localization
-
Davezac N, Baldin V, Gabrielli B, Forrest A, Theis-Febvre N, et al. 2000. Regulation of CDC25B phosphatases subcellular localization. Oncogene 19:2179-85
-
(2000)
Oncogene
, vol.19
, pp. 2179-2185
-
-
Davezac, N.1
Baldin, V.2
Gabrielli, B.3
Forrest, A.4
Theis-Febvre, N.5
-
42
-
-
0029042689
-
Raf1 interaction with Cdc25 phosphatase ties mitogenic signal transduction to cell cycle activation
-
Galaktionov K, Jessus C, Beach D. 1995. Raf1 interaction with Cdc25 phosphatase ties mitogenic signal transduction to cell cycle activation. Genes Dev. 9:1046-58
-
(1995)
Genes Dev.
, vol.9
, pp. 1046-1058
-
-
Galaktionov, K.1
Jessus, C.2
Beach, D.3
-
43
-
-
0033603454
-
Physical and functional interactions between Pim-1 kinase and Cdc25A phosphatase. Implications for the Pim-1-mediated activation of the c-Myc signaling pathway
-
Mochizuki T, Kitanaka C, Noguchi K, Muramatsu T, Asai A, Kuchino Y. 1999. Physical and functional interactions between Pim-1 kinase and Cdc25A phosphatase. Implications for the Pim-1-mediated activation of the c-Myc signaling pathway. J. Biol. Chem. 274:18659-66
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 18659-18666
-
-
Mochizuki, T.1
Kitanaka, C.2
Noguchi, K.3
Muramatsu, T.4
Asai, A.5
Kuchino, Y.6
-
44
-
-
1842486794
-
Cdc25A phosphatase: Combinatorial phosphorylation, ubiquitylation and proteolysis
-
Busino L, Chiesa M, Draetta GF, Donzelli M. 2004. Cdc25A phosphatase: combinatorial phosphorylation, ubiquitylation and proteolysis. Oncogene 23:2050-56
-
(2004)
Oncogene
, vol.23
, pp. 2050-2056
-
-
Busino, L.1
Chiesa, M.2
Draetta, G.F.3
Donzelli, M.4
-
45
-
-
0033063743
-
Tyrosine phosphorylation of the proto-oncoprotein Raf-1 is regulated by Raf-1 itself and the phosphatase Cdc25A
-
Xia K, Lee RS, Narsimhan RP, Mukhopadhyay NK, Neel BG, Roberts TM. 1999. Tyrosine phosphorylation of the proto-oncoprotein Raf-1 is regulated by Raf-1 itself and the phosphatase Cdc25A. Mol. Cell Biol. 19:4819-24
-
(1999)
Mol. Cell Biol
, vol.19
, pp. 4819-4824
-
-
Xia, K.1
Lee, R.S.2
Narsimhan, R.P.3
Mukhopadhyay, N.K.4
Neel, B.G.5
Roberts, T.M.6
-
46
-
-
0037205484
-
Identification of epidermal growth factor receptor as a target of Cdc25A protein phosphatase
-
Wang Z, Wang M, Lazo JS, Carr BI. 2002. Identification of epidermal growth factor receptor as a target of Cdc25A protein phosphatase. J. Biol. Chem. 277:19470-75
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 19470-19475
-
-
Wang, Z.1
Wang, M.2
Lazo, J.S.3
Carr, B.I.4
-
47
-
-
0346095286
-
Activation of the Raf-1/MEK/Erk kinase pathway by a novel Cdc25 inhibitor in human prostate cancer cells
-
Nemoto K, Vogt A, Oguri T, Lazo JS. 2004. Activation of the Raf-1/MEK/Erk kinase pathway by a novel Cdc25 inhibitor in human prostate cancer cells. Prostate 58:95-102
-
(2004)
Prostate
, vol.58
, pp. 95-102
-
-
Nemoto, K.1
Vogt, A.2
Oguri, T.3
Lazo, J.S.4
-
48
-
-
0041529687
-
Phosphorylation at serine 75 is required for UV-mediated degradation of human Cdc25A phosphatase at the S-phase checkpoint
-
Hassepass I, Voit R, Hoffmann I. 2003. Phosphorylation at serine 75 is required for UV-mediated degradation of human Cdc25A phosphatase at the S-phase checkpoint. J. Biol. Chem. 278:29824-29
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 29824-29829
-
-
Hassepass, I.1
Voit, R.2
Hoffmann, I.3
-
49
-
-
0035545996
-
Mammalian G1- and S-phase checkpoints in response to DNA damage
-
Bartek J, Lukas J. 2001. Mammalian G1- and S-phase checkpoints in response to DNA damage. Curr. Opin. Cell Biol. 13:738-47
-
(2001)
Curr. Opin. Cell Biol.
, vol.13
, pp. 738-747
-
-
Bartek, J.1
Lukas, J.2
-
50
-
-
0036467486
-
p38 and Chk1 kinases: Different conductors for the G(2)/M checkpoint symphony
-
Bulavin DV, Amundson SA, Fornace AJ. 2002. p38 and Chk1 kinases: different conductors for the G(2)/M checkpoint symphony. Curr. Opin. Genet. Dev. 12:92-97
-
(2002)
Curr. Opin. Genet. Dev.
, vol.12
, pp. 92-97
-
-
Bulavin, D.V.1
Amundson, S.A.2
Fornace, A.J.3
-
51
-
-
0037133189
-
Arsenite-induced Cdc25C degradation is through the KEN-box and ubiquitin-proteasome pathway
-
Chen F, Zhang Z, Bower J, Lu Y, Leonard SS, et al. 2002. Arsenite-induced Cdc25C degradation is through the KEN-box and ubiquitin-proteasome pathway. Proc. Natl. Acad. Sci. USA 99:1990-95
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 1990-1995
-
-
Chen, F.1
Zhang, Z.2
Bower, J.3
Lu, Y.4
Leonard, S.S.5
-
52
-
-
0035799557
-
Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase
-
Bulavin DV, Higashimoto Y, Popoff IJ, Gaarde WA, Basrur V, et al. 2001. Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase. Nature 411:102-7
-
(2001)
Nature
, vol.411
, pp. 102-107
-
-
Bulavin, D.V.1
Higashimoto, Y.2
Popoff, I.J.3
Gaarde, W.A.4
Basrur, V.5
-
53
-
-
0242497228
-
Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage
-
Busino L, Donzelli M, Chiesa M, Guardavaccaro D, Ganoth D, et al. 2003. Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage. Nature 426:87-91
-
(2003)
Nature
, vol.426
, pp. 87-91
-
-
Busino, L.1
Donzelli, M.2
Chiesa, M.3
Guardavaccaro, D.4
Ganoth, D.5
-
54
-
-
0347361537
-
SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25 A protein phosphatase
-
Jin J, Shirogane T, Xu L, Nalepa G, Qin J, et al. 2003. SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25 A protein phosphatase. Genes Dev. 17:3062-74
-
(2003)
Genes Dev.
, vol.17
, pp. 3062-3074
-
-
Jin, J.1
Shirogane, T.2
Xu, L.3
Nalepa, G.4
Qin, J.5
-
55
-
-
0033735581
-
Cell cycle checkpoints and their inactivation in human cancer
-
Molinari M. 2000. Cell cycle checkpoints and their inactivation in human cancer. Cell Prolif. 33:261-74
-
(2000)
Cell Prolif.
, vol.33
, pp. 261-274
-
-
Molinari, M.1
-
57
-
-
0035282334
-
Mammalian MAP kinase signalling cascades
-
Chang L, Karin M. 2001. Mammalian MAP kinase signalling cascades. Nature 410:37-40
-
(2001)
Nature
, vol.410
, pp. 37-40
-
-
Chang, L.1
Karin, M.2
-
58
-
-
0035313868
-
Combinatorial control of the specificity of protein tyrosine phosphatases
-
Tonks NK, Neel BG. 2001. Combinatorial control of the specificity of protein tyrosine phosphatases. Curr. Opin. Cell Biol. 13:182-95
-
(2001)
Curr. Opin. Cell Biol.
, vol.13
, pp. 182-195
-
-
Tonks, N.K.1
Neel, B.G.2
-
59
-
-
0034096201
-
Protein phosphatases and the regulation of mitogen-activated protein kinase signalling
-
Keyse SM. 2000. Protein phosphatases and the regulation of mitogen-activated protein kinase signalling. Curr. Opin. Cell Biol. 12:186-92
-
(2000)
Curr. Opin. Cell Biol.
, vol.12
, pp. 186-192
-
-
Keyse, S.M.1
-
60
-
-
0035923698
-
Activation of the Jnk signaling pathway by a dual-specificity phosphatase, JSP-1
-
Shen Y, Luche R, Wei B, Gordon ML, Diltz CD, Tonks NK. 2001. Activation of the Jnk signaling pathway by a dual-specificity phosphatase, JSP-1. Proc. Natl. Acad. Sci. USA 98:13613-18
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 13613-13618
-
-
Shen, Y.1
Luche, R.2
Wei, B.3
Gordon, M.L.4
Diltz, C.D.5
Tonks, N.K.6
-
61
-
-
0026570140
-
cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein
-
Charles CH, Abler AS, Lau LF. 1992. cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein. Oncogene 7:187-90
-
(1992)
Oncogene
, vol.7
, pp. 187-190
-
-
Charles, C.H.1
Abler, A.S.2
Lau, L.F.3
-
62
-
-
0027254428
-
The growth factor-inducible immediate-early gene 3CH134 encodes a protein-tyrosine-phosphatase
-
Charles CH, Sun H, Lau LF, Tonks NK. 1993. The growth factor-inducible immediate-early gene 3CH134 encodes a protein-tyrosine-phosphatase. Proc. Natl. Acad. Sci. USA 90:5292-96
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 5292-5296
-
-
Charles, C.H.1
Sun, H.2
Lau, L.F.3
Tonks, N.K.4
-
63
-
-
0027358722
-
MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo
-
Sun H, Charles CH, Lau LF, Tonks NK. 1993. MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo. Cell 75:487-93
-
(1993)
Cell
, vol.75
, pp. 487-493
-
-
Sun, H.1
Charles, C.H.2
Lau, L.F.3
Tonks, N.K.4
-
64
-
-
0026779540
-
Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase
-
Keyse SM, Emslie EA. 1992. Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase. Nature 359:644-47
-
(1992)
Nature
, vol.359
, pp. 644-647
-
-
Keyse, S.M.1
Emslie, E.A.2
-
65
-
-
2042538029
-
Structure and regulation of MAPK phosphatases
-
Farooq A, Zhou MM. 2004. Structure and regulation of MAPK phosphatases. Cell. Signal. 16:769-79
-
(2004)
Cell. Signal.
, vol.16
, pp. 769-779
-
-
Farooq, A.1
Zhou, M.M.2
-
66
-
-
0042355729
-
Activation of ERK induces phosphorylation of MAPK phosphatase-7, a JNK specific phosphatase, at Ser-446
-
Masuda K, Shima H, Katagiri C, Kikuchi K. 2003. Activation of ERK induces phosphorylation of MAPK phosphatase-7, a JNK specific phosphatase, at Ser-446. J. Biol. Chem. 278:32448-56
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 32448-32456
-
-
Masuda, K.1
Shima, H.2
Katagiri, C.3
Kikuchi, K.4
-
67
-
-
0031033716
-
The dual specificity mitogen-activated protein kinase phosphatase-1 and -2 are induced by the p42/p44MAPK cascade
-
Brondello JM, Brunei A, Pouyssegur J, McKenzie FR. 1997. The dual specificity mitogen-activated protein kinase phosphatase-1 and -2 are induced by the p42/p44MAPK cascade. J. Biol. Chem. 272:1368-76
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 1368-1376
-
-
Brondello, J.M.1
Brunei, A.2
Pouyssegur, J.3
McKenzie, F.R.4
-
68
-
-
0031775763
-
Isolation of the human genes encoding the pyst1 and Pyst2 phosphatases: Characterisation of Pyst2 as a cytosolic dual-specificity MAP kinase phosphatase and its catalytic activation by both MAP and SAP kinases
-
Dowd S, Sneddon AA, Keyse SM. 1998. Isolation of the human genes encoding the pyst1 and Pyst2 phosphatases: characterisation of Pyst2 as a cytosolic dual-specificity MAP kinase phosphatase and its catalytic activation by both MAP and SAP kinases. J. Cell Sci. 111:3389-99
-
(1998)
J. Cell Sci.
, vol.111
, pp. 3389-3399
-
-
Dowd, S.1
Sneddon, A.A.2
Keyse, S.M.3
-
69
-
-
0030013327
-
Activation of the mitogen-activated protein kinase pathway induces transcription of the PAC-1 phosphatase gene
-
Grumont RJ, Rasko JE, Strasser A, Gerondakis S. 1996. Activation of the mitogen-activated protein kinase pathway induces transcription of the PAC-1 phosphatase gene. Mol. Cell. Biol. 16:2913-21
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 2913-2921
-
-
Grumont, R.J.1
Rasko, J.E.2
Strasser, A.3
Gerondakis, S.4
-
70
-
-
0029905354
-
Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase
-
Groom LA, Sneddon AA, Alessi DR, Dowd S, Keyse SM. 1996. Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase. EMBO J. 15:3621-32
-
(1996)
EMBO J.
, vol.15
, pp. 3621-3632
-
-
Groom, L.A.1
Sneddon, A.A.2
Alessi, D.R.3
Dowd, S.4
Keyse, S.M.5
-
71
-
-
0037131170
-
Brain genomic response following hypoxia and re-oxygenation in the neonatal rat. Identification of genes that might contribute to hypoxia-induced ischemic tolerance
-
Bernaudin M, Tang Y, Reilly M, Petit E, Sharp FR. 2002. Brain genomic response following hypoxia and re-oxygenation in the neonatal rat. Identification of genes that might contribute to hypoxia-induced ischemic tolerance. J. Biol. Chem. 277:39728-38
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 39728-39738
-
-
Bernaudin, M.1
Tang, Y.2
Reilly, M.3
Petit, E.4
Sharp, F.R.5
-
72
-
-
0033617186
-
Mitogen-activated protein kinase phosphatase-1 (MKP-1) expression is induced by low oxygen conditions found in solid tumor microenvironments. A candidate MKP for the inactivation of hypoxia-inducible stress-activated protein kinase/c-Jun N-terminal protein kinase activity
-
Laderoute KR, Mendonca HL, Calaoagan JM, Knapp AM, Giaccia AJ, Stork PJ. 1999. Mitogen-activated protein kinase phosphatase-1 (MKP-1) expression is induced by low oxygen conditions found in solid tumor microenvironments. A candidate MKP for the inactivation of hypoxia-inducible stress-activated protein kinase/c-Jun N-terminal protein kinase activity. J. Biol. Chem. 274:12890-97
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 12890-12897
-
-
Laderoute, K.R.1
Mendonca, H.L.2
Calaoagan, J.M.3
Knapp, A.M.4
Giaccia, A.J.5
Stork, P.J.6
-
73
-
-
0035977013
-
Hyppxia-induced regulation of MAPK phosphatase-1 as identified by subtractive suppression hybridization and cDNA microarray analysis
-
Seta KA, Kim R, Kim HW, Millhorn DE, Beitner-Johnson D. 2001. Hyppxia-induced regulation of MAPK phosphatase-1 as identified by subtractive suppression hybridization and cDNA microarray analysis. J. Biol. Chem. 276:44405-12
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 44405-44412
-
-
Seta, K.A.1
Kim, R.2
Kim, H.W.3
Millhorn, D.E.4
Beitner-Johnson, D.5
-
74
-
-
0038832564
-
Reduced MAP kinase phosphatase-1 degradation after p42/p44MAPK- dependent phosphorylation
-
Brondello JM, Pouyssegur J, McKenzie FR. 1999. Reduced MAP kinase phosphatase-1 degradation after p42/p44MAPK- dependent phosphorylation. Science 286:2514-17
-
(1999)
Science
, vol.286
, pp. 2514-2517
-
-
Brondello, J.M.1
Pouyssegur, J.2
McKenzie, F.R.3
-
75
-
-
0032557632
-
Catalytic activation of the phosphatase MKP-3 by ERK2 mitogen-activated protein kinase
-
Camps M, Nichols A, Gillieron C, Antonsson B, Muda M, et al. 1998. Catalytic activation of the phosphatase MKP-3 by ERK2 mitogen-activated protein kinase. Science 280:1262-65
-
(1998)
Science
, vol.280
, pp. 1262-1265
-
-
Camps, M.1
Nichols, A.2
Gillieron, C.3
Antonsson, B.4
Muda, M.5
-
76
-
-
0038721205
-
c-Myc oncogene and Cdc25A cell activating phosphatase expression in non-Hodgkin's lymphoma
-
Aref S, Fouda M, El Dosoky E, Menessy A, Mabed M, et al. 2003. c-Myc oncogene and Cdc25A cell activating phosphatase expression in non-Hodgkin's lymphoma. Hematology 8:183-90
-
(2003)
Hematology
, vol.8
, pp. 183-190
-
-
Aref, S.1
Fouda, M.2
El Dosoky, E.3
Menessy, A.4
Mabed, M.5
-
77
-
-
0344393475
-
Distinct modes of deregulation of the proto-oncogenic Cdc25A phosphatase in human breast cancer cell lines
-
Loffler H, Syljuasen RG, Bartkova J, Worm J, Lukas J, Bartek J. 2003. Distinct modes of deregulation of the proto-oncogenic Cdc25A phosphatase in human breast cancer cell lines. Oncogene 22:8063-71
-
(2003)
Oncogene
, vol.22
, pp. 8063-8071
-
-
Loffler, H.1
Syljuasen, R.G.2
Bartkova, J.3
Worm, J.4
Lukas, J.5
Bartek, J.6
-
78
-
-
0033635191
-
The cell cycle Cdc25 A tyrosine phosphatase is activated in degenerating postmitotic neurons in Alzheimer's disease
-
Ding XL, Husseman J, Tomashevski A, Nochlin D, Jin LW, Vincent I. 2000. The cell cycle Cdc25 A tyrosine phosphatase is activated in degenerating postmitotic neurons in Alzheimer's disease. Am. J. Pathol. 157:1983-90
-
(2000)
Am. J. Pathol.
, vol.157
, pp. 1983-1990
-
-
Ding, X.L.1
Husseman, J.2
Tomashevski, A.3
Nochlin, D.4
Jin, L.W.5
Vincent, I.6
-
79
-
-
0035881867
-
Constitutive Cdc25B tyrosine phosphatase activity in adult brain neurons with M phase-type alterations in Alzheimer's disease
-
Vincent I, Bu B, Hudson K, Husseman J, Nochlin D, Jin L. 2001. Constitutive Cdc25B tyrosine phosphatase activity in adult brain neurons with M phase-type alterations in Alzheimer's disease. Neuroscience 105:639-50
-
(2001)
Neuroscience
, vol.105
, pp. 639-650
-
-
Vincent, I.1
Bu, B.2
Hudson, K.3
Husseman, J.4
Nochlin, D.5
Jin, L.6
-
80
-
-
0029119560
-
CDC25 phosphatases as potential human oncogenes
-
Galaktionov K, Lee AK, Eckstein J, Draetta G, Meckler J, et al. 1995. CDC25 phosphatases as potential human oncogenes. Science 269:1575-77
-
(1995)
Science
, vol.269
, pp. 1575-1577
-
-
Galaktionov, K.1
Lee, A.K.2
Eckstein, J.3
Draetta, G.4
Meckler, J.5
-
81
-
-
0033575959
-
Increased susceptibility to carcinogen-induced mammary tumors in MMTV-Cdc25B transgenic mice
-
Yao Y, Slosberg ED, Wang L, Hibshoosh H, Zhang YJ, et al. 1999. Increased susceptibility to carcinogen-induced mammary tumors in MMTV-Cdc25B transgenic mice. Oncogene 18:5159-66
-
(1999)
Oncogene
, vol.18
, pp. 5159-5166
-
-
Yao, Y.1
Slosberg, E.D.2
Wang, L.3
Hibshoosh, H.4
Zhang, Y.J.5
-
82
-
-
0033549866
-
Induction of mammary gland hyperplasia in transgenic mice overexpressing human Cdc25B
-
Ma ZQ, Chua SS, DeMayo FJ, Tsai SY. 1999. Induction of mammary gland hyperplasia in transgenic mice overexpressing human Cdc25B. Oncogene 18:4564-76
-
(1999)
Oncogene
, vol.18
, pp. 4564-4576
-
-
Ma, Z.Q.1
Chua, S.S.2
DeMayo, F.J.3
Tsai, S.Y.4
-
83
-
-
0035171497
-
Cdc25B functions as a novel coactivator for the steroid receptors
-
Ma ZQ, Liu Z, Ngan ES, Tsai SY. 2001. Cdc25B functions as a novel coactivator for the steroid receptors. Mol. Cell Biol. 21:8056-67
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 8056-8067
-
-
Ma, Z.Q.1
Liu, Z.2
Ngan, E.S.3
Tsai, S.Y.4
-
84
-
-
0034949255
-
The cell cycle-regulatory CDC25A phosphatase inhibits apoptosis signal-regulating kinase 1
-
Zou X, Tsutsui T, Ray D, Blomquist JF, Ichijo H, et al. 2001. The cell cycle-regulatory CDC25A phosphatase inhibits apoptosis signal-regulating kinase 1. Mol. Cell Biol. 21:4818-28
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 4818-4828
-
-
Zou, X.1
Tsutsui, T.2
Ray, D.3
Blomquist, J.F.4
Ichijo, H.5
-
85
-
-
0028868944
-
Growth inhibition of hepatoma cells induced by vitamin K and its analogs
-
Nishikawa Y, Carr BI, Wang M, Kar S, Finn F, et al. 1995. Growth inhibition of hepatoma cells induced by vitamin K and its analogs. J. Biol. Chem. 270:28304-10
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 28304-28310
-
-
Nishikawa, Y.1
Carr, B.I.2
Wang, M.3
Kar, S.4
Finn, F.5
-
86
-
-
0031028381
-
Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway
-
Pumiglia KM, Decker SJ. 1997. Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway. Proc. Natl. Acad. Sci. USA 94:448-52
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 448-452
-
-
Pumiglia, K.M.1
Decker, S.J.2
-
87
-
-
0034923671
-
Neuronal apoptosis at the G1/S cell cycle checkpoint
-
Liu DX, Greene LA. 2001. Neuronal apoptosis at the G1/S cell cycle checkpoint. Cell Tissue Res. 305:217-28
-
(2001)
Cell Tissue Res.
, vol.305
, pp. 217-228
-
-
Liu, D.X.1
Greene, L.A.2
-
88
-
-
0033037948
-
Re-entry into the cell cycle: A mechanism for neurodegeneration in Alzheimer disease
-
McShea A, Wahl AF, Smith MA. 1999. Re-entry into the cell cycle: a mechanism for neurodegeneration in Alzheimer disease. Med. Hypotheses 52:525-27
-
(1999)
Med. Hypotheses
, vol.52
, pp. 525-527
-
-
McShea, A.1
Wahl, A.F.2
Smith, M.A.3
-
89
-
-
0031661968
-
The cell division cycle and the pathophysiology of Alzheimer's disease
-
Nagy Z, Esiri MM, Smith AD. 1998. The cell division cycle and the pathophysiology of Alzheimer's disease. Neuroscience 87:731-39
-
(1998)
Neuroscience
, vol.87
, pp. 731-739
-
-
Nagy, Z.1
Esiri, M.M.2
Smith, A.D.3
-
90
-
-
0033551712
-
Cell cycle-related protein expression in vascular dementia and Alzheimer's disease
-
Smith MZ, Nagy Z, Esiri MM. 1999. Cell cycle-related protein expression in vascular dementia and Alzheimer's disease. Neurosci. Lett. 211:45-48
-
(1999)
Neurosci. Lett.
, vol.211
, pp. 45-48
-
-
Smith, M.Z.1
Nagy, Z.2
Esiri, M.M.3
-
91
-
-
1342333775
-
Cell cycle activation linked to neuronal cell death initiated by DNA damage
-
Kruman II, Wersto RP, Cardozo-Pelaez F, Smilenov L, Chan SL, et al. 2004. Cell cycle activation linked to neuronal cell death initiated by DNA damage. Neuron 41:549-61
-
(2004)
Neuron
, vol.41
, pp. 549-561
-
-
Kruman, I.I.1
Wersto, R.P.2
Cardozo-Pelaez, F.3
Smilenov, L.4
Chan, S.L.5
-
92
-
-
0031006939
-
Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain
-
Vincent I, Jicha G, Rosado M, Dickson DW. 1997. Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain. J. Neurosci. 17:3588-98
-
(1997)
J. Neurosci.
, vol.17
, pp. 3588-3598
-
-
Vincent, I.1
Jicha, G.2
Rosado, M.3
Dickson, D.W.4
-
93
-
-
0037442820
-
Cyclin-dependent kinase activity is required for apoptotic death but not inclusion formation in cortical neurons after proteasomal inhibition
-
Rideout HJ, Wang Q, Park DS, Stefanis L. 2003. Cyclin-dependent kinase activity is required for apoptotic death but not inclusion formation in cortical neurons after proteasomal inhibition. J. Neurosci. 23:1237-45
-
(2003)
J. Neurosci.
, vol.23
, pp. 1237-1245
-
-
Rideout, H.J.1
Wang, Q.2
Park, D.S.3
Stefanis, L.4
-
94
-
-
0038243934
-
Potential tumor suppressive pathway involving DUSP6/MKP-3 in pancreatic cancer
-
Furukawa T, Sunamura M, Motoi F, Matsuno S, Horii A. 2003. Potential tumor suppressive pathway involving DUSP6/MKP-3 in pancreatic cancer. Am. J. Pathol. 162:1807-15
-
(2003)
Am. J. Pathol.
, vol.162
, pp. 1807-1815
-
-
Furukawa, T.1
Sunamura, M.2
Motoi, F.3
Matsuno, S.4
Horii, A.5
-
95
-
-
0023637278
-
Deletion of a DNA sequence at the chromosomal region 3p21 in all major types of lung cancer
-
Kok K, Osinga J, Carritt B, Davis MB, van der Hout AH, et al. 1987. Deletion of a DNA sequence at the chromosomal region 3p21 in all major types of lung cancer. Nature 330:578-81
-
(1987)
Nature
, vol.330
, pp. 578-581
-
-
Kok, K.1
Osinga, J.2
Carritt, B.3
Davis, M.B.4
Van Der Hout, A.H.5
-
96
-
-
0011153988
-
Consistent chromosome 3p deletion and loss of heterozygosity in renal cell carcinoma
-
Kovacs G, Erlandsson R, Boldog F, Ingvarsson S, Muller-Brechlin R, et al. 1988. Consistent chromosome 3p deletion and loss of heterozygosity in renal cell carcinoma. Proc. Natl. Acad. Sci. USA 85:1571-75
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 1571-1575
-
-
Kovacs, G.1
Erlandsson, R.2
Boldog, F.3
Ingvarsson, S.4
Muller-Brechlin, R.5
-
97
-
-
0033768481
-
Expression and comparative chromosomal mapping of MKP-5 genes DUSP10/Dusp10
-
Masuda K, Shima H, Kikuchi K, Watanabe Y, Matsuda Y. 2000. Expression and comparative chromosomal mapping of MKP-5 genes DUSP10/Dusp10. Cytogenet. Cell Genet. 90:71-74
-
(2000)
Cytogenet. Cell Genet.
, vol.90
, pp. 71-74
-
-
Masuda, K.1
Shima, H.2
Kikuchi, K.3
Watanabe, Y.4
Matsuda, Y.5
-
98
-
-
0029088784
-
Allelic imbalance in gastric cancer: An affected site on chromosome arm 3p
-
Schneider BG, Pulitzer DR, Brown RD, Prihoda TJ, Bostwick DG, et al. 1995. Allelic imbalance in gastric cancer: an affected site on chromosome arm 3p. Genes Chromosomes Cancer 13:263-71
-
(1995)
Genes Chromosomes Cancer
, vol.13
, pp. 263-271
-
-
Schneider, B.G.1
Pulitzer, D.R.2
Brown, R.D.3
Prihoda, T.J.4
Bostwick, D.G.5
-
99
-
-
9344222738
-
Analysis of 99 microdissected prostate carcinomas reveals a high frequency of allelic loss on chromosome 8p12-21
-
Vocke CD, Pozzatti RO, Bostwick DG, Florence CD, Jennings SB, et al. 1996. Analysis of 99 microdissected prostate carcinomas reveals a high frequency of allelic loss on chromosome 8p12-21. Cancer Res. 56:2411-16
-
(1996)
Cancer Res.
, vol.56
, pp. 2411-2416
-
-
Vocke, C.D.1
Pozzatti, R.O.2
Bostwick, D.G.3
Florence, C.D.4
Jennings, S.B.5
-
100
-
-
0024371674
-
Loss of heterozygosity on the short arm of chromosome 3 in carcinoma of the uterine cervix
-
Yokota J, Tsukada Y, Nakajima T, Gotoh M, Shimosato Y, et al. 1989. Loss of heterozygosity on the short arm of chromosome 3 in carcinoma of the uterine cervix. Cancer Res. 49:3598-601
-
(1989)
Cancer Res.
, vol.49
, pp. 3598-3601
-
-
Yokota, J.1
Tsukada, Y.2
Nakajima, T.3
Gotoh, M.4
Shimosato, Y.5
-
101
-
-
9244244243
-
A member of the MAP kinase phosphatase gene family in mouse containing a complex trinucleotide repeat in the coding region
-
Theodosiou AM, Rodrigues NR, Nesbit MA, Ambrose HJ, Paterson H, et al. 1996. A member of the MAP kinase phosphatase gene family in mouse containing a complex trinucleotide repeat in the coding region. Hum. Mol. Genet. 5:675-84
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 675-684
-
-
Theodosiou, A.M.1
Rodrigues, N.R.2
Nesbit, M.A.3
Ambrose, H.J.4
Paterson, H.5
-
102
-
-
0028276007
-
Three tumor-suppressor regions on chromosome lip identified by high-resolution deletion mapping in human non-small-cell lung cancer
-
Bepler G, Garcia-Blanco MA. 1994. Three tumor-suppressor regions on chromosome lip identified by high-resolution deletion mapping in human non-small-cell lung cancer. Proc. Natl. Acad. Sci. USA 91:5513-17
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 5513-5517
-
-
Bepler, G.1
Garcia-Blanco, M.A.2
-
103
-
-
0344873757
-
MAPK phosphatase DUSP16/MKP-7, a candidate tumor suppressor for chromosome region 12p12-13, reduces BCR-ABL-induced transformation
-
Hoornaert I, Marynen P, Goris J, Sciot R, Baens M. 2003. MAPK phosphatase DUSP16/MKP-7, a candidate tumor suppressor for chromosome region 12p12-13, reduces BCR-ABL-induced transformation. Oncogene 22:7728-36
-
(2003)
Oncogene
, vol.22
, pp. 7728-7736
-
-
Hoornaert, I.1
Marynen, P.2
Goris, J.3
Sciot, R.4
Baens, M.5
-
104
-
-
0036119568
-
A detailed transcriptional map of the chromosome 12p12 tumour suppressor locus
-
Montpetit A, Boily G, Sinnett D. 2002. A detailed transcriptional map of the chromosome 12p12 tumour suppressor locus. Eur. J. Hum. Genet. 10:62-71
-
(2002)
Eur. J. Hum. Genet.
, vol.10
, pp. 62-71
-
-
Montpetit, A.1
Boily, G.2
Sinnett, D.3
-
105
-
-
0027939754
-
Chromosomal localization of four human VH1-like protein-tyrosine phosphatases
-
Martell KJ, Kwak S, Hakes DJ, Dixon JE, Trent JM. 1994. Chromosomal localization of four human VH1-like protein-tyrosine phosphatases. Genomics 22:462-64
-
(1994)
Genomics
, vol.22
, pp. 462-464
-
-
Martell, K.J.1
Kwak, S.2
Hakes, D.J.3
Dixon, J.E.4
Trent, J.M.5
-
106
-
-
0035863372
-
Chromosomal imbalances associated with response to chemotherapy and cytotoxic cytokines in human malignant glioma cell lines
-
Weber RG, Rieger J, Naumann U, Lichter P, Weller M. 2001. Chromosomal imbalances associated with response to chemotherapy and cytotoxic cytokines in human malignant glioma cell lines. Int. J. Cancer 91:213-18
-
(2001)
Int. J. Cancer
, vol.91
, pp. 213-218
-
-
Weber, R.G.1
Rieger, J.2
Naumann, U.3
Lichter, P.4
Weller, M.5
-
107
-
-
0035212658
-
Comparative genomic hybridization detects novel amplifications in fibroadenomas of the breast
-
Ojopi EP, Rogatto SR, Caldeira JR, Barbieri-Neto J, Squire JA. 2001. Comparative genomic hybridization detects novel amplifications in fibroadenomas of the breast. Genes Chromosomes Cancer 30:25-31
-
(2001)
Genes Chromosomes Cancer
, vol.30
, pp. 25-31
-
-
Ojopi, E.P.1
Rogatto, S.R.2
Caldeira, J.R.3
Barbieri-Neto, J.4
Squire, J.A.5
-
108
-
-
0029922544
-
Deletion mapping identifies loss of heterozygosity at 5p15.1-15.2, 5q11 and 5q34-35 in human male germ cell tumors
-
Murty VV, Reuter VE, Bosl GJ, Chaganti RS. 1996. Deletion mapping identifies loss of heterozygosity at 5p15.1-15.2, 5q11 and 5q34-35 in human male germ cell tumors. Oncogene 12:2719-23
-
(1996)
Oncogene
, vol.12
, pp. 2719-2723
-
-
Murty, V.V.1
Reuter, V.E.2
Bosl, G.J.3
Chaganti, R.S.4
-
109
-
-
0033609402
-
Chromosomal deletions occur in restricted regions of 5q in testicular germ cell cancer
-
Peng HQ, Liu L, Goss PE, Bailey D, Hogg D. 1999. Chromosomal deletions occur in restricted regions of 5q in testicular germ cell cancer. Oncogene 18:3277-83
-
(1999)
Oncogene
, vol.18
, pp. 3277-3283
-
-
Peng, H.Q.1
Liu, L.2
Goss, P.E.3
Bailey, D.4
Hogg, D.5
-
110
-
-
0034027646
-
Molecular genetic analysis of malignant ovarian germ cell tumors
-
Faulkner SW, Friedlander ML. 2000. Molecular genetic analysis of malignant ovarian germ cell tumors. Gynecol. Oncol. 77:283-88
-
(2000)
Gynecol. Oncol.
, vol.77
, pp. 283-288
-
-
Faulkner, S.W.1
Friedlander, M.L.2
-
111
-
-
0028329773
-
The CL100 gene, which encodes a dual specificity (Tyr/Thr) MAP kinase phosphatase, is highly conserved and maps to human chromosome 5q34
-
Emslie EA, Jones TA, Sheer D, Keyse SM. 1994. The CL100 gene, which encodes a dual specificity (Tyr/Thr) MAP kinase phosphatase, is highly conserved and maps to human chromosome 5q34. Hum. Genet. 93:513-16
-
(1994)
Hum. Genet.
, vol.93
, pp. 513-516
-
-
Emslie, E.A.1
Jones, T.A.2
Sheer, D.3
Keyse, S.M.4
-
112
-
-
0029757347
-
Disruption of the erp/mkp-1 gene does not affect mouse development: Normal MAP kinase activity in ERP/MKP-1-deficient fibroblasts
-
Dorfman K, Carrasco D, Gruda M, Ryan C, Lira SA, Bravo R. 1996. Disruption of the erp/mkp-1 gene does not affect mouse development: normal MAP kinase activity in ERP/MKP-1-deficient fibroblasts. Oncogene 13:925-31
-
(1996)
Oncogene
, vol.13
, pp. 925-931
-
-
Dorfman, K.1
Carrasco, D.2
Gruda, M.3
Ryan, C.4
Lira, S.A.5
Bravo, R.6
-
113
-
-
0029890896
-
Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation
-
Khosravi-Far R, White MA, Westwick JK, Solski PA, Chrzanowska-Wodnicka M, et al. 1996. Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation. Mol. Cell Biol. 16:3923-33
-
(1996)
Mol. Cell Biol.
, vol.16
, pp. 3923-3933
-
-
Khosravi-Far, R.1
White, M.A.2
Westwick, J.K.3
Solski, P.A.4
Chrzanowska-Wodnicka, M.5
-
114
-
-
0031036906
-
Mitogen-activated protein kinase phosphatase 1 is overexpressed in prostate cancers and is inversely related to apoptosis
-
Magi-Galluzzi C, Mishra R, Fiorentino M, Montironi R, Yao H, et al. 1997. Mitogen-activated protein kinase phosphatase 1 is overexpressed in prostate cancers and is inversely related to apoptosis. Lab. Invest. 76:37-51
-
(1997)
Lab. Invest.
, vol.76
, pp. 37-51
-
-
Magi-Galluzzi, C.1
Mishra, R.2
Fiorentino, M.3
Montironi, R.4
Yao, H.5
-
115
-
-
0032497287
-
Increased MAPK activity and MKP-1 overexpression in human gastric adenocarcinoma
-
Bang YJ, Kwon JH, Kang SH, Kim JW, Yang YC. 1998. Increased MAPK activity and MKP-1 overexpression in human gastric adenocarcinoma. Biochem. Biophys. Res. Commun. 250:43-47
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.250
, pp. 43-47
-
-
Bang, Y.J.1
Kwon, J.H.2
Kang, S.H.3
Kim, J.W.4
Yang, Y.C.5
-
116
-
-
0037430452
-
Overexpression of mitogen-activated protein kinase phosphatases MKP1, MKP2 in human breast cancer
-
Wang HY, Cheng Z, Malbon CC. 2003. Overexpression of mitogen-activated protein kinase phosphatases MKP1, MKP2 in human breast cancer. Cancer Lett. 191:229-37
-
(2003)
Cancer Lett.
, vol.191
, pp. 229-237
-
-
Wang, H.Y.1
Cheng, Z.2
Malbon, C.C.3
-
117
-
-
0037606170
-
Down-regulation of the dual-specificity phosphatase MKP-1 suppresses tumorigenicity of pancreatic cancer cells
-
Liao Q, Guo J, Kleeff J, Zimmermann A, Buchler MW, et al. 2003. Down-regulation of the dual-specificity phosphatase MKP-1 suppresses tumorigenicity of pancreatic cancer cells. Gastroenterology 124:1830-45
-
(2003)
Gastroenterology
, vol.124
, pp. 1830-1845
-
-
Liao, Q.1
Guo, J.2
Kleeff, J.3
Zimmermann, A.4
Buchler, M.W.5
-
118
-
-
0037058703
-
Expression of mitogen-activated protein kinase phosphatase-1 (MKP-1) in primary human ovarian carcinoma
-
Denkert C, Schmitt WD, Berger S, Reles A, Pest S, et al. 2002. Expression of mitogen-activated protein kinase phosphatase-1 (MKP-1) in primary human ovarian carcinoma. Int. J. Cancer 102:507-13
-
(2002)
Int. J. Cancer
, vol.102
, pp. 507-513
-
-
Denkert, C.1
Schmitt, W.D.2
Berger, S.3
Reles, A.4
Pest, S.5
-
119
-
-
0029904681
-
Expression of mitogen-activated protein kinase phosphatase-1 in the early phases of human epithelial carcinogenesis
-
Loda M, Capodieci P, Mishra R, Yao H, Corless C, et al. 1996. Expression of mitogen-activated protein kinase phosphatase-1 in the early phases of human epithelial carcinogenesis. Am. J. Pathol. 149:1553-64
-
(1996)
Am. J. Pathol.
, vol.149
, pp. 1553-1564
-
-
Loda, M.1
Capodieci, P.2
Mishra, R.3
Yao, H.4
Corless, C.5
-
120
-
-
0032539919
-
Conditional expression of mitogen-activated protein kinase phosphatase-1, MKP-1, is cytoprotective against UV-induced apoptosis
-
Franklin CC, Srikanth S, Kraft AS. 1998. Conditional expression of mitogen-activated protein kinase phosphatase-1, MKP-1, is cytoprotective against UV-induced apoptosis. Proc. Natl. Acad. Sci. USA 95:3014-19
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 3014-3019
-
-
Franklin, C.C.1
Srikanth, S.2
Kraft, A.S.3
-
121
-
-
0028924419
-
Role of mitogen-activated protein kinase phosphatase during the cellular response to genotoxic stress. Inhibition of c-Jun N- terminal kinase activity and AP-1-dependent gene activation
-
Liu Y, Gorospe M, Yang C, Holbrook NJ. 1995. Role of mitogen-activated protein kinase phosphatase during the cellular response to genotoxic stress. Inhibition of c-Jun N- terminal kinase activity and AP-1-dependent gene activation. J. Biol. Chem. 270:8377-80
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 8377-8380
-
-
Liu, Y.1
Gorospe, M.2
Yang, C.3
Holbrook, N.J.4
-
122
-
-
0034718760
-
CL100/MKP-1 modulates JNK activation and apoptosis in response to cisplatin
-
Sanchez-Perez I, Martinez-Gomariz M, Williams D, Keyse SM, Perona R. 2000. CL100/MKP-1 modulates JNK activation and apoptosis in response to cisplatin. Oncogene 19:5142-52
-
(2000)
Oncogene
, vol.19
, pp. 5142-5152
-
-
Sanchez-Perez, I.1
Martinez-Gomariz, M.2
Williams, D.3
Keyse, S.M.4
Perona, R.5
-
123
-
-
1342343926
-
Common alterations in gene expression and increased proliferation in recurrent acute myeloid leukemia
-
Staber PB, Linkesch W, Zauner D, Beham-Schmid C, Guelly C, et al. 2004. Common alterations in gene expression and increased proliferation in recurrent acute myeloid leukemia. Oncogene 23:894-904
-
(2004)
Oncogene
, vol.23
, pp. 894-904
-
-
Staber, P.B.1
Linkesch, W.2
Zauner, D.3
Beham-Schmid, C.4
Guelly, C.5
-
124
-
-
0038488950
-
A multigenic program mediating breast cancer metastasis to bone
-
Kang Y, Siegel PM, Shu W, Drobnjak M, Kakonen SM, et al. 2003. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 3:537-49
-
(2003)
Cancer Cell
, vol.3
, pp. 537-549
-
-
Kang, Y.1
Siegel, P.M.2
Shu, W.3
Drobnjak, M.4
Kakonen, S.M.5
-
125
-
-
0037392444
-
Issues and progress with protein kinase inhibitors for cancer treatment
-
Dancey J, Sausville EA. 2003. Issues and progress with protein kinase inhibitors for cancer treatment. Nat. Rev. Drug Discov. 2:296-313
-
(2003)
Nat. Rev. Drug Discov.
, vol.2
, pp. 296-313
-
-
Dancey, J.1
Sausville, E.A.2
-
126
-
-
18144432725
-
Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A
-
Fauman EB, Cogswell JP, Lovejoy B, Rocque WJ, Holmes W, et al. 1998. Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A. Cell 93:617-25
-
(1998)
Cell
, vol.93
, pp. 617-625
-
-
Fauman, E.B.1
Cogswell, J.P.2
Lovejoy, B.3
Rocque, W.J.4
Holmes, W.5
-
127
-
-
0032738102
-
Crystal structure of the catalytic subunit of Cdc25B required for G2/M phase transition of the cell cycle
-
Reynolds RA, Yem AW, Wolfe CL, Deibel MR Jr, Chidester CG, Watenpaugh KD. 1999. Crystal structure of the catalytic subunit of Cdc25B required for G2/M phase transition of the cell cycle. J. Mol. Biol. 293:559-68
-
(1999)
J. Mol. Biol.
, vol.293
, pp. 559-568
-
-
Reynolds, R.A.1
Yem, A.W.2
Wolfe, C.L.3
Deibel Jr., M.R.4
Chidester, C.G.5
Watenpaugh, K.D.6
-
129
-
-
0029816291
-
Dysidiolide: A novel protein phosphatase inhibitor from the Caribbean sponge Dysidea etheria de Laubenfels
-
Gunasekera SP, McCarthy PJ, Kelly-Borges M, Lobkovsky E, Clardy J. 1996. Dysidiolide: a novel protein phosphatase inhibitor from the Caribbean sponge Dysidea etheria de Laubenfels. J. Am. Chem. Soc. 118:8759-60
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 8759-8760
-
-
Gunasekera, S.P.1
McCarthy, P.J.2
Kelly-Borges, M.3
Lobkovsky, E.4
Clardy, J.5
-
130
-
-
0031080770
-
Studies on menadione as an inhibitor of the cdc25 phosphatase
-
Ham SW, Park HJ, Lim DH. 1997. Studies on menadione as an inhibitor of the cdc25 phosphatase. Bioorg. Chem. 25:33-36
-
(1997)
Bioorg. Chem.
, vol.25
, pp. 33-36
-
-
Ham, S.W.1
Park, H.J.2
Lim, D.H.3
-
131
-
-
0028063505
-
Dnacin A1 and dnacin B1 are antitumor antibiotics that inhibit cdc25B phosphatase activity
-
Horiguchi T, Nishi K, Hakoda S, Tanida S, Nagata A, Okayama H. 1994. Dnacin A1 and dnacin B1 are antitumor antibiotics that inhibit cdc25B phosphatase activity. Biochem. Pharmacol. 48:2139-41
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 2139-2141
-
-
Horiguchi, T.1
Nishi, K.2
Hakoda, S.3
Tanida, S.4
Nagata, A.5
Okayama, H.6
-
132
-
-
0034812565
-
Coscinosulfate, a CDC25 phosphatase inhibitor from the sponge Coscinoderma mathewsi
-
Loukaci A, Le SI, Samadi M, Leclerc S, Damiens E, et al. 2001. Coscinosulfate, a CDC25 phosphatase inhibitor from the sponge Coscinoderma mathewsi. Bioorg. Med. Chem. 9:3049-54
-
(2001)
Bioorg. Med. Chem.
, vol.9
, pp. 3049-3054
-
-
Loukaci, A.1
Le, S.I.2
Samadi, M.3
Leclerc, S.4
Damiens, E.5
-
133
-
-
0037026007
-
Separation of Cdc25 dual specificity phosphatase inhibition and DNA cleaving activities in a focused library of analogs of the antitumor antibiotic Dnacin
-
Wipf P, Hopkins CR, Phillips EO, Lazo JS. 2002. Separation of Cdc25 dual specificity phosphatase inhibition and DNA cleaving activities in a focused library of analogs of the antitumor antibiotic Dnacin. Tetrahedron 58:6367-72
-
(2002)
Tetrahedron
, vol.58
, pp. 6367-6372
-
-
Wipf, P.1
Hopkins, C.R.2
Phillips, E.O.3
Lazo, J.S.4
-
134
-
-
0032482536
-
Stereoselective synthesis of the core structure of the protein phosphatase inhibitor dysidiolide
-
Brohm D, Waldmann H. 1998. Stereoselective synthesis of the core structure of the protein phosphatase inhibitor dysidiolide. Tetrahedron Lett. 39:3995-98
-
(1998)
Tetrahedron Lett.
, vol.39
, pp. 3995-3998
-
-
Brohm, D.1
Waldmann, H.2
-
135
-
-
0037126836
-
Natural products are biologically validated starting points in structural space for compound library development: Solid-phase synthesis of dysidiolide-derived phosp hatase inhibitors
-
Brohm D, Metzger S, Bhargava A, Muller O, Lieb F, Waldmann H. 2001. Natural products are biologically validated starting points in structural space for compound library development: Solid-phase synthesis of dysidiolide-derived phosp hatase inhibitors. Angew. Chem.-Int. Ed. 41:307-11
-
(2001)
Angew. Chem.-Int. Ed.
, vol.41
, pp. 307-311
-
-
Brohm, D.1
Metzger, S.2
Bhargava, A.3
Muller, O.4
Lieb, F.5
Waldmann, H.6
-
136
-
-
0035959985
-
Synthesis of a tetronic acid library focused on inhibitors of tyrosine and dual-specificity protein phosphatases and its evaluation regarding VHR and cdc25B inhibition
-
Sodeoka M, Sampe R, Kojima S, Baba Y, Usui T, et al. 2001. Synthesis of a tetronic acid library focused on inhibitors of tyrosine and dual-specificity protein phosphatases and its evaluation regarding VHR and cdc25B inhibition. J. Med. Chem. 44:3216-22
-
(2001)
J. Med. Chem.
, vol.44
, pp. 3216-3222
-
-
Sodeoka, M.1
Sampe, R.2
Kojima, S.3
Baba, Y.4
Usui, T.5
-
137
-
-
0041315929
-
Binding and inhibition of Cdc25 phosphatases by vitamin K analogues
-
Kar S, Lefterov IM, Wang M, Lazo JS, Scott CN, et al. 2003. Binding and inhibition of Cdc25 phosphatases by vitamin K analogues. Biochemistry 42:10490-97
-
(2003)
Biochemistry
, vol.42
, pp. 10490-10497
-
-
Kar, S.1
Lefterov, I.M.2
Wang, M.3
Lazo, J.S.4
Scott, C.N.5
-
138
-
-
0035798185
-
Total synthesis and determination of the absolute configuration of coscinosulfate. A new selective inhibitor of Cdc25 protein phosphatase
-
Poigny S, Nouri S, Chiaroni A, Guyot M, Samadi M. 2001. Total synthesis and determination of the absolute configuration of coscinosulfate. A new selective inhibitor of Cdc25 protein phosphatase. J. Org. Chem. 66:7263-69
-
(2001)
J. Org. Chem.
, vol.66
, pp. 7263-7269
-
-
Poigny, S.1
Nouri, S.2
Chiaroni, A.3
Guyot, M.4
Samadi, M.5
-
139
-
-
0033964566
-
Synthesis and biological evaluation of a targeted library of protein phosphatase inhibitors
-
Wipf P, Aslan DC, Luci DK, Southwick EC, Lazo JS. 2000. Synthesis and biological evaluation of a targeted library of protein phosphatase inhibitors. Biotechnol Bioeng. 71:58-70
-
(2000)
Biotechnol Bioeng.
, vol.71
, pp. 58-70
-
-
Wipf, P.1
Aslan, D.C.2
Luci, D.K.3
Southwick, E.C.4
Lazo, J.S.5
-
140
-
-
13844318588
-
-
2001. JP Patent No. 2003104964
-
Kitaide M, Nagai K, Terada T, Asao T, Sugimoto Y, Yamada Y. 2001. JP Patent No. 2003104964
-
-
-
Kitaide, M.1
Nagai, K.2
Terada, T.3
Asao, T.4
Sugimoto, Y.5
Yamada, Y.6
-
141
-
-
0035282975
-
Syntheses and biological activities of a novel group of steroidal derived inhibitors for human Cdc25A protein phosphatase
-
Peng H, Xie W, Otterness DM, Cogswell JP, McConnell RT, et al. 2001. Syntheses and biological activities of a novel group of steroidal derived inhibitors for human Cdc25A protein phosphatase. J. Med. Chem. 44:834-48
-
(2001)
J. Med. Chem.
, vol.44
, pp. 834-848
-
-
Peng, H.1
Xie, W.2
Otterness, D.M.3
Cogswell, J.P.4
McConnell, R.T.5
-
144
-
-
0037777745
-
Inhibition of Cdc25 phosphatases by indolyldihydroxyquinones
-
Sohn J, Kiburz B, Li Z, Deng L, Safi A, et al. 2003. Inhibition of Cdc25 phosphatases by indolyldihydroxyquinones. J. Med. Chem. 46:2580-88
-
(2003)
J. Med. Chem.
, vol.46
, pp. 2580-2588
-
-
Sohn, J.1
Kiburz, B.2
Li, Z.3
Deng, L.4
Safi, A.5
-
145
-
-
0035935711
-
Discovery and biological evaluation of a new family of potent inhibitors of the dual specificity protein phosphatase Cdc25
-
Lazo JS, Asian DC, Southwick EC, Cooley KA, Ducruet AP, et al. 2001. Discovery and biological evaluation of a new family of potent inhibitors of the dual specificity protein phosphatase Cdc25. J. Med. Chem. 44:4042-49
-
(2001)
J. Med. Chem.
, vol.44
, pp. 4042-4049
-
-
Lazo, J.S.1
Asian, D.C.2
Southwick, E.C.3
Cooley, K.A.4
Ducruet, A.P.5
-
146
-
-
18344375627
-
Identification of a potent and selective pharmacophore for Cdc25 dual specificity phosphatase inhibitors
-
Lazo JS, Nemoto K, Pestell KE, Cooley K, Southwick EC, et al. 2002. Identification of a potent and selective pharmacophore for Cdc25 dual specificity phosphatase inhibitors. Mol. Pharmacol. 61:720-28
-
(2002)
Mol. Pharmacol.
, vol.61
, pp. 720-728
-
-
Lazo, J.S.1
Nemoto, K.2
Pestell, K.E.3
Cooley, K.4
Southwick, E.C.5
-
147
-
-
0035847677
-
Sulfonylated aminothiazoles as new small molecule inhibitors of protein phosphatases
-
Wipf P, Aslan DC, Southwick EC, Lazo JS. 2001. Sulfonylated aminothiazoles as new small molecule inhibitors of protein phosphatases. Bioorg. Med. Chem. Lett. 11:313-17
-
(2001)
Bioorg. Med. Chem. Lett.
, vol.11
, pp. 313-317
-
-
Wipf, P.1
Aslan, D.C.2
Southwick, E.C.3
Lazo, J.S.4
-
148
-
-
13844317152
-
-
2002. WO Patent No. 2003050098
-
Pfahl M, Al shamma HA, Fanjul AN, Pleynet DPM, Bao H, et al. 2002. WO Patent No. 2003050098
-
-
-
Pfahl, M.1
Al Shamma, H.A.2
Fanjul, A.N.3
Pleynet, D.P.M.4
Bao, H.5
-
149
-
-
2342455204
-
A novel synthetic inhibitor of CDC25 phosphatases: BN82002
-
Brezak MC, Quaranta M, Mondesert O, Galcera MO, Lavergne O, et al. 2004. A novel synthetic inhibitor of CDC25 phosphatases: BN82002. Cancer Res. 64:3320-25
-
(2004)
Cancer Res.
, vol.64
, pp. 3320-3325
-
-
Brezak, M.C.1
Quaranta, M.2
Mondesert, O.3
Galcera, M.O.4
Lavergne, O.5
-
150
-
-
13844310095
-
-
2001. U.S. Patent No. 2002183249
-
Taylor NR, Borhani D, Epstein D, Rudolph J, Ritter K, et al. 2001. U.S. Patent No. 2002183249
-
-
-
Taylor, N.R.1
Borhani, D.2
Epstein, D.3
Rudolph, J.4
Ritter, K.5
-
151
-
-
12144290332
-
Design and synthesis of macrocyclic inhibitors of phosphatase Cdc25B
-
Baurle S, Blume T, Gunther J, Henschel D, Hillig RC, et al. 2004. Design and synthesis of macrocyclic inhibitors of phosphatase Cdc25B. Bioorg. Med. Chem. Lett. 14:1673-77
-
(2004)
Bioorg. Med. Chem. Lett.
, vol.14
, pp. 1673-1677
-
-
Baurle, S.1
Blume, T.2
Gunther, J.3
Henschel, D.4
Hillig, R.C.5
-
152
-
-
0041913991
-
Cell-active dual specificity phosphatase inhibitors identified by high-content screening
-
Vogt A, Cooley KA, Brisson M, Tarpley MG, Wipf P, Lazo JS. 2003. Cell-active dual specificity phosphatase inhibitors identified by high-content screening. Chem. Biol. 10:733-42
-
(2003)
Chem. Biol.
, vol.10
, pp. 733-742
-
-
Vogt, A.1
Cooley, K.A.2
Brisson, M.3
Tarpley, M.G.4
Wipf, P.5
Lazo, J.S.6
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