-
1
-
-
13344261980
-
Differential structural requirements for interaction of Ras protein with its distinct downstream effectors
-
Akasaka, K., M. Tamada, F. Wang, K. Kariya, F. Shima, A. Kikuchi, M. Yamamoto, M. Shirouzu, S. Yokoyama, and T. Kataoka. 1996. Differential structural requirements for interaction of Ras protein with its distinct downstream effectors. J. Biol. Chem. 271:5353-5360.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 5353-5360
-
-
Akasaka, K.1
Tamada, M.2
Wang, F.3
Kariya, K.4
Shima, F.5
Kikuchi, A.6
Yamamoto, M.7
Shirouzu, M.8
Yokoyama, S.9
Kataoka, T.10
-
2
-
-
0029099408
-
Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and Raf
-
Alessi, D. R., P. Cohen, A. Ashworth, S. Cowley, S. J. Leevers, and C. J. Marshall. 1995. Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and Raf. Methods Enzymol. 255:279-290.
-
(1995)
Methods Enzymol.
, vol.255
, pp. 279-290
-
-
Alessi, D.R.1
Cohen, P.2
Ashworth, A.3
Cowley, S.4
Leevers, S.J.5
Marshall, C.J.6
-
3
-
-
0028293931
-
raf-1
-
raf-1. EMBO J. 13:1610-1619.
-
(1994)
EMBO J.
, vol.13
, pp. 1610-1619
-
-
Alessi, D.R.1
Saito, V.2
Campbell, D.G.3
Cohen, P.4
Sithanandam, G.5
Rapp, U.6
Ashworth, A.7
Marshall, C.J.8
Cowley, S.9
-
4
-
-
0024564417
-
Characterization and expression of the human rhoH12 gene product
-
Avraham, H., and R. A. Weinberg. 1989. Characterization and expression of the human rhoH12 gene product. Mol. Cell. Biol. 9:2058-2066.
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 2058-2066
-
-
Avraham, H.1
Weinberg, R.A.2
-
5
-
-
0022470480
-
Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins
-
Bar-Sagi, D., and J. R. Feramisco. 1986. Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins. Science 233:1061-1068.
-
(1986)
Science
, vol.233
, pp. 1061-1068
-
-
Bar-Sagi, D.1
Feramisco, J.R.2
-
6
-
-
0027732538
-
Proteins regulating Ras and its relatives
-
Boguski, M. S., and F. McCormick. 1993. Proteins regulating Ras and its relatives. Nature (London) 366:643-654.
-
(1993)
Nature (London)
, vol.366
, pp. 643-654
-
-
Boguski, M.S.1
McCormick, F.2
-
7
-
-
0021915337
-
Structure and biological activity of human homologs of the ruflmil oncogene
-
Bonner, T. I., S. B. Kerby, P. Sutrave, M. A. Gunnell, G. Mark, and U. R. Rapp. 1985. Structure and biological activity of human homologs of the ruflmil oncogene. Mol. Cell. Biol. 5:1400-1407.
-
(1985)
Mol. Cell. Biol.
, vol.5
, pp. 1400-1407
-
-
Bonner, T.I.1
Kerby, S.B.2
Sutrave, P.3
Gunnell, M.A.4
Mark, G.5
Rapp, U.R.6
-
8
-
-
0029102080
-
RAS signalling is abnormal in a c-raf1 MEK1 double mutant
-
Bottorff, D., S. Stang, S. Agellon, and J. C. Stone. 1995. RAS signalling is abnormal in a c-raf1 MEK1 double mutant. Mol. Cell. Biol. 15:5113-5122.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 5113-5122
-
-
Bottorff, D.1
Stang, S.2
Agellon, S.3
Stone, J.C.4
-
9
-
-
0025010979
-
The GTPase superfamily: A conserved switch for diverse cell functions
-
Bourne, H. R., D. A. Sanders, and F. McCormick. 1990. The GTPase superfamily: a conserved switch for diverse cell functions. Nature (London) 348:125-132.
-
(1990)
Nature (London)
, vol.348
, pp. 125-132
-
-
Bourne, H.R.1
Sanders, D.A.2
McCormick, F.3
-
10
-
-
0027937264
-
Cooperative interaction of S. pombe proteins required for mating and morphogenesis
-
Chang, E. C., M. Barr, Y. Wang, V. Jung, H.-P. Xu, and M. H. Wigler. 1994. Cooperative interaction of S. pombe proteins required for mating and morphogenesis. Cell 79:131-141.
-
(1994)
Cell
, vol.79
, pp. 131-141
-
-
Chang, E.C.1
Barr, M.2
Wang, Y.3
Jung, V.4
Xu, H.-P.5
Wigler, M.H.6
-
11
-
-
0028915743
-
GTPase cascades choreographing cellular behavior: Movement, morphogenesis and more
-
Chant, J., and L. Stowers. 1995. GTPase cascades choreographing cellular behavior: movement, morphogenesis and more. Cell 81:1-4.
-
(1995)
Cell
, vol.81
, pp. 1-4
-
-
Chant, J.1
Stowers, L.2
-
12
-
-
0029118592
-
Biological assays for Ras transformation
-
Clark, G. J., A. D. Cox, S. M. Graham, and C. J. Der. 1995. Biological assays for Ras transformation. Methods Enzymol. 255:395-412.
-
(1995)
Methods Enzymol.
, vol.255
, pp. 395-412
-
-
Clark, G.J.1
Cox, A.D.2
Graham, S.M.3
Der, C.J.4
-
13
-
-
0029055812
-
The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
-
Coso, O. A., M. Chiariello, J.-C. Yu, H. Teramoto, P. Crespo, N. Xu, T. Miki, and J. S. Gutkind. 1995. The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell 81:1137-1146.
-
(1995)
Cell
, vol.81
, pp. 1137-1146
-
-
Coso, O.A.1
Chiariello, M.2
Yu, J.-C.3
Teramoto, H.4
Crespo, P.5
Xu, N.6
Miki, T.7
Gutkind, J.S.8
-
14
-
-
0028228616
-
Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
-
Cowley, S., H. Paterson, P. Kemp, and C. J. Marshall. 1994. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 77:841-852.
-
(1994)
Cell
, vol.77
, pp. 841-852
-
-
Cowley, S.1
Paterson, H.2
Kemp, P.3
Marshall, C.J.4
-
15
-
-
0029097751
-
Analysis of Ras protein expression in mammalian cells
-
Cox, A. D., P. A. Solski, J. D. Jordan, and C. J. Der. 1995. Analysis of Ras protein expression in mammalian cells. Methods Enzymol. 255:195-221.
-
(1995)
Methods Enzymol.
, vol.255
, pp. 195-221
-
-
Cox, A.D.1
Solski, P.A.2
Jordan, J.D.3
Der, C.J.4
-
16
-
-
0026641090
-
Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro
-
Dent, P., W. Haser, T. A. J. Haystead, L. A. Vincent, T. M. Roberts, and T. W. Sturgill. 1992. Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro. Science 257:1404-1407.
-
(1992)
Science
, vol.257
, pp. 1404-1407
-
-
Dent, P.1
Haser, W.2
Haystead, T.A.J.3
Vincent, L.A.4
Roberts, T.M.5
Sturgill, T.W.6
-
17
-
-
0022471217
-
Biological and biochemical properties of human rasH genes mutated at codon 61
-
Der, C. J., T. Finkel, and G. M. Cooper. 1986. Biological and biochemical properties of human rasH genes mutated at codon 61. Cell 44:167-176.
-
(1986)
Cell
, vol.44
, pp. 167-176
-
-
Der, C.J.1
Finkel, T.2
Cooper, G.M.3
-
18
-
-
0026679892
-
Raf functions downstream of Ras1 in the sevenless signal transduction pathway
-
Dickson, B., F. Sprenger, D. Morrison, and E. Hafen. 1992. Raf functions downstream of Ras1 in the sevenless signal transduction pathway. Nature (London) 360:600-603.
-
(1992)
Nature (London)
, vol.360
, pp. 600-603
-
-
Dickson, B.1
Sprenger, F.2
Morrison, D.3
Hafen, E.4
-
19
-
-
0026760422
-
Rac and rho in tune
-
Downward, J. 1992. Rac and rho in tune. Nature (London) 359:273-274.
-
(1992)
Nature (London)
, vol.359
, pp. 273-274
-
-
Downward, J.1
-
20
-
-
0030053105
-
Ras interaction with two distinct binding domains in Raf-1 may be required for Ras transformation
-
Drugan, J. K., R. Khosravi-Far, M. A. White, C. J. Der, Y.-J. Sung, Y.-W. Huang, and S. L. Campbell. 1996. Ras interaction with two distinct binding domains in Raf-1 may be required for Ras transformation. J. Biol. Chem. 271:233-237.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 233-237
-
-
Drugan, J.K.1
Khosravi-Far, R.2
White, M.A.3
Der, C.J.4
Sung, Y.-J.5
Huang, Y.-W.6
Campbell, S.L.7
-
21
-
-
0027422247
-
The pathway to signal achievement
-
Egan, S. E., and R. A. Weinberg. 1993. The pathway to signal achievement. Nature (London) 365:781-783.
-
(1993)
Nature (London)
, vol.365
, pp. 781-783
-
-
Egan, S.E.1
Weinberg, R.A.2
-
22
-
-
0027364980
-
Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase
-
Fabian, J. R., I. O. Daar, and D. K. Morrison. 1993. Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase. Mol. Cell. Biol. 13:7170-7179.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 7170-7179
-
-
Fabian, J.R.1
Daar, I.O.2
Morrison, D.K.3
-
23
-
-
0027215221
-
The many roads that lead to Ras
-
Feig, L. A. 1993. The many roads that lead to Ras. Science 260:767-768.
-
(1993)
Science
, vol.260
, pp. 767-768
-
-
Feig, L.A.1
-
24
-
-
0023715225
-
Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP
-
Feig, L. A., and G. M. Cooper. 1988. Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP. Mol. Cell. Biol. 8:3235-3243.
-
(1988)
Mol. Cell. Biol.
, vol.8
, pp. 3235-3243
-
-
Feig, L.A.1
Cooper, G.M.2
-
25
-
-
0025373180
-
Ras and GAP - Who's controlling whom?
-
Hall, A. 1990. ras and GAP - who's controlling whom? Cell 61:921-923.
-
(1990)
Cell
, vol.61
, pp. 921-923
-
-
Hall, A.1
-
26
-
-
0027587322
-
Ras-related proteins
-
Hall, A. 1993. Ras-related proteins. Curr. Biol. 5:265-268.
-
(1993)
Curr. Biol.
, vol.5
, pp. 265-268
-
-
Hall, A.1
-
27
-
-
0028859266
-
A human protein selected for interference with Ras function interacts directly with Ras and competes with Rafl
-
Han, L., and J. Colicelli. 1995. A human protein selected for interference with Ras function interacts directly with Ras and competes with Rafl. Mol. Cell. Biol. 15:1318-1323.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 1318-1323
-
-
Han, L.1
Colicelli, J.2
-
28
-
-
0027263251
-
C. elegans lin-45 raf gene participates in let-60 ras-stimulated vulval differentiation
-
Han, M., A. Golden, Y. Han, and P. W. Sternberg. 1993. C. elegans lin-45 raf gene participates in let-60 ras-stimulated vulval differentiation. Nature (London) 363:133-140.
-
(1993)
Nature (London)
, vol.363
, pp. 133-140
-
-
Han, M.1
Golden, A.2
Han, Y.3
Sternberg, P.W.4
-
29
-
-
0029128482
-
Ras-mediated transcription activation: Analysis by transient cotransfection assays
-
Hauser, C. A., J. K. Westwick, and L. A. Quilliam. 1995. Ras-mediated transcription activation: analysis by transient cotransfection assays. Methods Enzymol. 255:412-426.
-
(1995)
Methods Enzymol.
, vol.255
, pp. 412-426
-
-
Hauser, C.A.1
Westwick, J.K.2
Quilliam, L.A.3
-
30
-
-
0027191808
-
Functional analysis of a growth factor-responsive transcription factor complex
-
Hill, C. S., R. Marais, S. John, J. Wynne, S. Dalton, and R. Treisman. 1993 Functional analysis of a growth factor-responsive transcription factor complex. Cell 73:385-406.
-
(1993)
Cell
, vol.73
, pp. 385-406
-
-
Hill, C.S.1
Marais, R.2
John, S.3
Wynne, J.4
Dalton, S.5
Treisman, R.6
-
31
-
-
0028897113
-
Transcriptional regulation by extracellular signals: Mechanisms and specificity
-
Hill, C. S., and R. Treisman. 1995. Transcriptional regulation by extracellular signals: mechanisms and specificity. Cell 80:199-211.
-
(1995)
Cell
, vol.80
, pp. 199-211
-
-
Hill, C.S.1
Treisman, R.2
-
32
-
-
0029015774
-
The Rho family GTPases RhoA, Rac1 and Cdc42Hs regulate transcriptional activation by SRF
-
Hill, C. S., J. Wynne, and R. Treisman. 1995. The Rho family GTPases RhoA, Rac1 and Cdc42Hs regulate transcriptional activation by SRF. Cell 81:1159-1170.
-
(1995)
Cell
, vol.81
, pp. 1159-1170
-
-
Hill, C.S.1
Wynne, J.2
Treisman, R.3
-
33
-
-
0028153277
-
Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator
-
Hofer, F., S. Fields, C. Schneider, and G. S. Martin. 1994. Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator. Proc. Natl. Acad. Sci. USA 91:11089-11093.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 11089-11093
-
-
Hofer, F.1
Fields, S.2
Schneider, C.3
Martin, G.S.4
-
34
-
-
0026754369
-
Activation of the MAP kinase pathway by the protein kinase raf
-
Howe, L. R., S. J. Leevers, N. Gómez, S. Nakielny, P. Cohen, and C. J. Marshall. 1992. Activation of the MAP kinase pathway by the protein kinase raf. Cell 71:335-342.
-
(1992)
Cell
, vol.71
, pp. 335-342
-
-
Howe, L.R.1
Leevers, S.J.2
Gómez, N.3
Nakielny, S.4
Cohen, P.5
Marshall, C.J.6
-
35
-
-
0028075246
-
Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras
-
Khosravi-Far, R., M. Chrzanowska-Wodnicka, P. A. Solski, A. Eva, K. Burridge, and C. J. Der. 1994. Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras. Mol. Cell. Biol. 14:6848-6857.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 6848-6857
-
-
Khosravi-Far, R.1
Chrzanowska-Wodnicka, M.2
Solski, P.A.3
Eva, A.4
Burridge, K.5
Der, C.J.6
-
37
-
-
0028800305
-
Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation
-
Khosravi-Far, R., P. A. Solski, G. J. Clark, M. S. Kinch, and C. J. Der. 1995. Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation. Mol. Cell. Biol. 15:6443-6453.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 6443-6453
-
-
Khosravi-Far, R.1
Solski, P.A.2
Clark, G.J.3
Kinch, M.S.4
Der, C.J.5
-
38
-
-
0027986765
-
RalGDS family members interact with the effector loop of ras p21
-
Kikuchi, A., S. D. Demo, Z.-H. Ye, Y.-W. Chen, and L. T. Williams. 1994. ralGDS family members interact with the effector loop of ras p21. Mol. Cell. Biol. 14:7483-7491.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 7483-7491
-
-
Kikuchi, A.1
Demo, S.D.2
Ye, Z.-H.3
Chen, Y.-W.4
Williams, L.T.5
-
39
-
-
0025979335
-
Raf-1 protein kinase is required for growth of induced NIH/3T3 cells
-
Kolch, W., G. Heidecker, P. Lloyd, and U. R. Rapp. 1991. Raf-1 protein kinase is required for growth of induced NIH/3T3 cells. Nature (London) 349:426-428.
-
(1991)
Nature (London)
, vol.349
, pp. 426-428
-
-
Kolch, W.1
Heidecker, G.2
Lloyd, P.3
Rapp, U.R.4
-
40
-
-
13344281006
-
Identification of AF-6 and Canoe as putative targets for Ras
-
Kuriyama, M., N. Harada, S. Kuroda, T. Yamamoto, M. Nakafuku, A. Iwamatsu, D. Yamamoto, R. Prasad, C. Croce, E. Canaani, and K. Kaibuchi. 1996. Identification of AF-6 and Canoe as putative targets for Ras. J. Biol. Chem. 271:607-610.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 607-610
-
-
Kuriyama, M.1
Harada, N.2
Kuroda, S.3
Yamamoto, T.4
Nakafuku, M.5
Iwamatsu, A.6
Yamamoto, D.7
Prasad, R.8
Croce, C.9
Canaani, E.10
Kaibuchi, K.11
-
41
-
-
0026647749
-
Raf-1 activates MAP kinase-kinase
-
Kyriakis, J. M., H. App. X.-F. Zhang, P. Banerjee, D. L. Brautigan, U. R. Rapp, and J. Avruch. 1992. Raf-1 activates MAP kinase-kinase. Nature (London) 358:417-421.
-
(1992)
Nature (London)
, vol.358
, pp. 417-421
-
-
Kyriakis, J.M.1
App, H.2
Zhang, X.-F.3
Banerjee, P.4
Brautigan, D.L.5
Rapp, U.R.6
Avruch, J.7
-
42
-
-
0027215820
-
A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf
-
Lange-Carter, C. A., C. M. Pleiman, A. M. Gardner, K. J. Blumer, and G. L. Johnson. 1993. A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf. Science 260:315-319.
-
(1993)
Science
, vol.260
, pp. 315-319
-
-
Lange-Carter, C.A.1
Pleiman, C.M.2
Gardner, A.M.3
Blumer, K.J.4
Johnson, G.L.5
-
43
-
-
0028272507
-
Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane
-
Leevers, S. J., H. F. Paterson, and C. J. Marshall. 1994. Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane. Nature (London) 369:411-414.
-
(1994)
Nature (London)
, vol.369
, pp. 411-414
-
-
Leevers, S.J.1
Paterson, H.F.2
Marshall, C.J.3
-
44
-
-
0028292062
-
Genetic and molecular analyses of mutations involved in Drosophila raf signal transduction
-
Lu, X., M. B. Melnick, J. Hsu, and N. Perrimon. 1994 Genetic and molecular analyses of mutations involved in Drosophila raf signal transduction. EMBO J. 13:2592-2599.
-
(1994)
EMBO J.
, vol.13
, pp. 2592-2599
-
-
Lu, X.1
Melnick, M.B.2
Hsu, J.3
Perrimon, N.4
-
45
-
-
0028141496
-
Transformation of mammalian cells by constitutively active MAP kinase kinase
-
Mansour, S. J., W. T. Matten, A. S. Hermann, J. M. Candia, S. Rong, K. Fukasawa, G. F. Vande Woude, and N. G. Ahn. 1994. Transformation of mammalian cells by constitutively active MAP kinase kinase. Science 265:966-970.
-
(1994)
Science
, vol.265
, pp. 966-970
-
-
Mansour, S.J.1
Matten, W.T.2
Hermann, A.S.3
Candia, J.M.4
Rong, S.5
Fukasawa, K.6
Vande Woude, G.F.7
Ahn, N.G.8
-
46
-
-
0027297647
-
The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain
-
Marais, R., J. Wynne, and R. Treisman. 1993. The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain. Cell 73:381-393.
-
(1993)
Cell
, vol.73
, pp. 381-393
-
-
Marais, R.1
Wynne, J.2
Treisman, R.3
-
47
-
-
0028872649
-
Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
-
Marshall, C. J. 1995. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80:179-185.
-
(1995)
Cell
, vol.80
, pp. 179-185
-
-
Marshall, C.J.1
-
49
-
-
0029070887
-
Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs
-
Minden, A., A. Lin, F.-X. Claret, A. Abo, and M. Karin. 1995. Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell 81:1147-1157.
-
(1995)
Cell
, vol.81
, pp. 1147-1157
-
-
Minden, A.1
Lin, A.2
Claret, F.-X.3
Abo, A.4
Karin, M.5
-
50
-
-
0027337519
-
Complexes of Ras-GTP with Raf-1 and mitogen-activated protein kinase kinase
-
Moodie, S. A., B. M. Willumsen, M. J. Weber, and A. Wolfman. 1993. Complexes of Ras-GTP with Raf-1 and mitogen-activated protein kinase kinase. Science 260:1658-1661.
-
(1993)
Science
, vol.260
, pp. 1658-1661
-
-
Moodie, S.A.1
Willumsen, B.M.2
Weber, M.J.3
Wolfman, A.4
-
51
-
-
0028096233
-
The 3 Rs of life: Ras. Raf and growth regulation
-
Moodie, S. A., and A. Wolfman. 1994. The 3 Rs of life: Ras. Raf and growth regulation. Trends Genet. 10:14-18.
-
(1994)
Trends Genet.
, vol.10
, pp. 14-18
-
-
Moodie, S.A.1
Wolfman, A.2
-
52
-
-
85033822486
-
Activation of the Raf/MAP kinase cascade is not sufficient for Ras transformation of R1E epithelial cells
-
in press
-
Oldham, S. M., G. J. Clark, L. M. Gangarosa, R. J. Coffey, and C. J. Der. Activation of the Raf/MAP kinase cascade is not sufficient for Ras transformation of R1E epithelial cells. Proc. Natl. Acad. Sci. USA, in press.
-
Proc. Natl. Acad. Sci. USA
-
-
Oldham, S.M.1
Clark, G.J.2
Gangarosa, L.M.3
Coffey, R.J.4
Der, C.J.5
-
55
-
-
0027191250
-
Tumorigenic activity of rho genes from Aplysia californica
-
Perona, R., P. Esteve, B. Jiménez, R. P. Ballestero, S. Ramón y Cajal, and J. C. Lacal. 1993. Tumorigenic activity of rho genes from Aplysia californica. Oncogene 8:1285-1292.
-
(1993)
Oncogene
, vol.8
, pp. 1285-1292
-
-
Perona, R.1
Esteve, P.2
Jiménez, B.3
Ballestero, R.P.4
Ramón y Cajal, S.5
Lacal, J.C.6
-
56
-
-
0027373678
-
Cloning of the ALL-1 fusion partner, the AF-6 gene, involved in acute myeloid leukemias with the t(6:11) chromosome translocation
-
Prasad, R., Y. Gu, H. Alder, T. Nakamura, O. Canaani, H. Saito, K. Huebner, R. P. Gale, P. C. Novell, K. Kuriyama, Y. Miyazaki, C. M. Croce, and E. Canaani. 1993. Cloning of the ALL-1 fusion partner, the AF-6 gene, involved in acute myeloid leukemias with the t(6:11) chromosome translocation. Cancer Res. 53:5624-5628.
-
(1993)
Cancer Res.
, vol.53
, pp. 5624-5628
-
-
Prasad, R.1
Gu, Y.2
Alder, H.3
Nakamura, T.4
Canaani, O.5
Saito, H.6
Huebner, K.7
Gale, R.P.8
Novell, P.C.9
Kuriyama, K.10
Miyazaki, Y.11
Croce, C.M.12
Canaani, E.13
-
57
-
-
0029057465
-
Critical role of RhoB in cell transformation by oncogenic Ras
-
Prendergast, G. C., R. Khosravi-Far, P. A. Solski, H. Kurzawa, P. F. Lebowitz, and C. J. Der. 1995. Critical role of RhoB in cell transformation by oncogenic Ras. Oncogene 10:2289-2296.
-
(1995)
Oncogene
, vol.10
, pp. 2289-2296
-
-
Prendergast, G.C.1
Khosravi-Far, R.2
Solski, P.A.3
Kurzawa, H.4
Lebowitz, P.F.5
Der, C.J.6
-
58
-
-
0029559310
-
A role for Rho in Ras transformation
-
Qiu, R.-G., J. Chen, F. McCormick, and M. Symons. 1995. A role for Rho in Ras transformation. Proc. Natl. Acad. Sci. USA 92:11781-11785.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 11781-11785
-
-
Qiu, R.-G.1
Chen, J.2
McCormick, F.3
Symons, M.4
-
59
-
-
0000552751
-
The GTPase Rac1 controls cell proliferation and cooperates with the MAP kinase pathway in fibroblast transformation
-
Qiu, R.-G., F. McCormick, and M. Symons. 1995. The GTPase Rac1 controls cell proliferation and cooperates with the MAP kinase pathway in fibroblast transformation. Nature (London) 374:457-459.
-
(1995)
Nature (London)
, vol.374
, pp. 457-459
-
-
Qiu, R.-G.1
McCormick, F.2
Symons, M.3
-
60
-
-
0029294676
-
Activators of Ras superfamily proteins
-
Quilliam, L. A., R. Khosravi-Far, S. Y. Huff, and C. J. Der. 1995. Activators of Ras superfamily proteins. Bioessays 17:395-404.
-
(1995)
Bioessays
, vol.17
, pp. 395-404
-
-
Quilliam, L.A.1
Khosravi-Far, R.2
Huff, S.Y.3
Der, C.J.4
-
61
-
-
0028356516
-
Elk-1 proteins interact with MAP kinases
-
Rao, V. N., and S. P. Reddy. 1994. elk-1 proteins interact with MAP kinases. Oncogene 9:1855-1860.
-
(1994)
Oncogene
, vol.9
, pp. 1855-1860
-
-
Rao, V.N.1
Reddy, S.P.2
-
62
-
-
0028965111
-
Biochemical analysis of MEK activation in NIH 3T3 fibroblasts
-
Reuter, C. W. M., A. D. Catling, T. Jelinek, and M. J. Weber. 1995. Biochemical analysis of MEK activation in NIH 3T3 fibroblasts. J. Biol. Chem. 270:7644-7655.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7644-7655
-
-
Reuter, C.W.M.1
Catling, A.D.2
Jelinek, T.3
Weber, M.J.4
-
63
-
-
0026778133
-
The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
-
Ridley, A. J., and A. Hall. 1992. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70:389-399.
-
(1992)
Cell
, vol.70
, pp. 389-399
-
-
Ridley, A.J.1
Hall, A.2
-
64
-
-
0026654125
-
The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
-
Ridley, A. J., H. F. Paterson, C. L. Johnston, D. Diekmann, and A. Hall. 1992. The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell 70:401-410.
-
(1992)
Cell
, vol.70
, pp. 401-410
-
-
Ridley, A.J.1
Paterson, H.F.2
Johnston, C.L.3
Diekmann, D.4
Hall, A.5
-
65
-
-
0027117408
-
A signal chain of events
-
Roberts, T. M. 1992. A signal chain of events. Nature (London) 360:534-535.
-
(1992)
Nature (London)
, vol.360
, pp. 534-535
-
-
Roberts, T.M.1
-
66
-
-
0028074316
-
Phosphatidylinositol-3-OH kinase as a direct target of Ras
-
Rodriguez-Viciana, P., P. H. Warne, R. Dhand, B. Vanhaesebroeck, I. Gout, M. J. Fry, M. D. Waterfield, and J. Downward. 1994. Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature (London) 370:527-532.
-
(1994)
Nature (London)
, vol.370
, pp. 527-532
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Dhand, R.3
Vanhaesebroeck, B.4
Gout, I.5
Fry, M.J.6
Waterfield, M.D.7
Downward, J.8
-
67
-
-
0029077563
-
Direct interaction between Ras and the kinase domain of mitogen-activited protein kinase kinase kinase (MEKK1)
-
Russell, M., C. A. Lange-Carter, and G. L. Johnson. 1995. Direct interaction between Ras and the kinase domain of mitogen-activited protein kinase kinase kinase (MEKK1). J. Biol. Chem. 270:11757-11760.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 11757-11760
-
-
Russell, M.1
Lange-Carter, C.A.2
Johnson, G.L.3
-
69
-
-
0027279176
-
How receptor tyrosine kinases activate Ras
-
Schlessinger, J. 1993. How receptor tyrosine kinases activate Ras. Trends Biochem. Sci. 18:273-275.
-
(1993)
Trends Biochem. Sci.
, vol.18
, pp. 273-275
-
-
Schlessinger, J.1
-
70
-
-
0027470176
-
Different structural organization of Ras and Rho effector domains
-
Self, A. J., H. F. Paterson, and A. Hall. 1993. Different structural organization of Ras and Rho effector domains. Oncogene 8:655-661.
-
(1993)
Oncogene
, vol.8
, pp. 655-661
-
-
Self, A.J.1
Paterson, H.F.2
Hall, A.3
-
71
-
-
0028206113
-
Mutations that abolish the ability of Ha-Ras to associate with Raf-1
-
Shirouzu, M., H. Koide, J. Fujita-Yoshigaki, H. Oshio, Y. Toyama, K. Yamasaki, S. A. Fuhrman, E. Villafranca, Y. Kaziro, and S. Yokoyama. 1994. Mutations that abolish the ability of Ha-Ras to associate with Raf-1. Oncogene 9:2153-2157.
-
(1994)
Oncogene
, vol.9
, pp. 2153-2157
-
-
Shirouzu, M.1
Koide, H.2
Fujita-Yoshigaki, J.3
Oshio, H.4
Toyama, Y.5
Yamasaki, K.6
Fuhrman, S.A.7
Villafranca, E.8
Kaziro, Y.9
Yokoyama, S.10
-
72
-
-
0022472990
-
Requirement for c-ras proteins during viral oncogene transformation
-
Smith, M. R., S. J. DeGudicibus, and D. W. Stacey. 1986. Requirement for c-ras proteins during viral oncogene transformation. Nature (London) 320: 540-543.
-
(1986)
Nature (London)
, vol.320
, pp. 540-543
-
-
Smith, M.R.1
Degudicibus, S.J.2
Stacey, D.W.3
-
73
-
-
0028577298
-
Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras and Rap
-
Spaargaren, M., and J. R. Bischoff. 1994. Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras and Rap. Proc. Natl. Acad. Sci. USA 91:12609-12613.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12609-12613
-
-
Spaargaren, M.1
Bischoff, J.R.2
-
74
-
-
0024545162
-
Definition of the human raf amino-terminal regulatory region by deletion mutagenesis
-
Stanton, V. P., Jr., D. W. Nichols, A. P. Laudano, and G. M. Cooper. 1989. Definition of the human raf amino-terminal regulatory region by deletion mutagenesis. Mol. Cell. Biol. 9:639-647.
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 639-647
-
-
Stanton Jr., V.P.1
Nichols, D.W.2
Laudano, A.P.3
Cooper, G.M.4
-
75
-
-
0028241533
-
Activation of Raf as a result of recruitment to the plasma membrane
-
Stokoe, D., S. G. Macdonald, K. Cadwallader, M. Symons, and J. F. Hancock. 1994. Activation of Raf as a result of recruitment to the plasma membrane. Science 264:1463-1467.
-
(1994)
Science
, vol.264
, pp. 1463-1467
-
-
Stokoe, D.1
Macdonald, S.G.2
Cadwallader, K.3
Symons, M.4
Hancock, J.F.5
-
76
-
-
0027407059
-
A protein kinase similar to MAP kinase activator acts downstream of the Raf kinase in Drosophila
-
Tsuda, L., Y. H. Inoue, M.-A. Yoo, M. Mizuno, M. Hata, Y.-M. Lim, T. Adachi-Yamada, H. Ryo, Y. Masamune, and Y. Nishida. 1993. A protein kinase similar to MAP kinase activator acts downstream of the Raf kinase in Drosophila. Cell 72:407-114.
-
(1993)
Cell
, vol.72
, pp. 407-1114
-
-
Tsuda, L.1
Inoue, Y.H.2
Yoo, M.-A.3
Mizuno, M.4
Hata, M.5
Lim, Y.-M.6
Adachi-Yamada, T.7
Ryo, H.8
Masamune, Y.9
Nishida, Y.10
-
77
-
-
0027161398
-
Complex formation between RAS and RAF and other protein kinases
-
Van Aelst, L., M. Barr, S. Marcus, A. Polverino, and M. Wigler. 1993. Complex formation between RAS and RAF and other protein kinases. Proc. Natl. Acad. Sci. USA 90:6213-6217.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 6213-6217
-
-
Van Aelst, L.1
Barr, M.2
Marcus, S.3
Polverino, A.4
Wigler, M.5
-
79
-
-
0027250250
-
Mammalian Ras interacts directly with the serine/threonine kinase Raf
-
Vojtek, A. B., S. M. Hollenberg, and J. A. Cooper. 1993. Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell 74:205-214.
-
(1993)
Cell
, vol.74
, pp. 205-214
-
-
Vojtek, A.B.1
Hollenberg, S.M.2
Cooper, J.A.3
-
80
-
-
0027200883
-
Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro
-
Warne, P. H., P. R. Viciana, and J. Downward. 1993. Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro. Nature (London) 364: 352-355.
-
(1993)
Nature (London)
, vol.364
, pp. 352-355
-
-
Warne, P.H.1
Viciana, P.R.2
Downward, J.3
-
81
-
-
0024513104
-
Expression of raf oncogenes activates the PEA1 transcription factor motif
-
Wasylyk, C., B. Wasylyk, G. Heidecker, M. Huleihel, and U. R. Rapp. 1989. Expression of raf oncogenes activates the PEA1 transcription factor motif. Mol. Cell. Biol. 9:2247-2250.
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 2247-2250
-
-
Wasylyk, C.1
Wasylyk, B.2
Heidecker, G.3
Huleihel, M.4
Rapp, U.R.5
-
82
-
-
0028201023
-
Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular-signal regulated kinases
-
Westwick, J. K., A. D. Cox, C. J. Der, M. H. Cobb, M. Hibi, M. Karin, and D. A. Brenner. 1994. Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular-signal regulated kinases. Proc. Natl. Acad. Sci. USA 91:6033-6034.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 6033-6034
-
-
Westwick, J.K.1
Cox, A.D.2
Der, C.J.3
Cobb, M.H.4
Hibi, M.5
Karin, M.6
Brenner, D.A.7
-
83
-
-
0028130213
-
Tumor necrosis factor alpha stimulates AP-1 activity through prolonged activation of the c-Jun kinase
-
Westwick, J. K., C. Weitzel, A. Minden, M. Karin, and D. A. Brenner. 1994. Tumor necrosis factor alpha stimulates AP-1 activity through prolonged activation of the c-Jun kinase. J. Biol. Chem. 269:26396-26401.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 26396-26401
-
-
Westwick, J.K.1
Weitzel, C.2
Minden, A.3
Karin, M.4
Brenner, D.A.5
-
84
-
-
0028948382
-
Multiple Ras functions can contribute to mammalian cell transformation
-
White, M. A., C. Nicolette, A. Minden, A. Polverino, L. Van Aelst, M. Karin, and M. H. Wigler. 1995. Multiple Ras functions can contribute to mammalian cell transformation. Cell 80:533-541.
-
(1995)
Cell
, vol.80
, pp. 533-541
-
-
White, M.A.1
Nicolette, C.2
Minden, A.3
Polverino, A.4
Van Aelst, L.5
Karin, M.6
Wigler, M.H.7
-
86
-
-
0024151614
-
Studies of Ras function in Saccharomyces cerevisiae
-
Wigler, M., J. Field, S. Powers, D. Broek, T. Toda, S. Cameron, J. Nikawa, T. Michaeli, J. Colicelli, and K. Ferguson. 1988. Studies of Ras function in Saccharomyces cerevisiae. Cold Spring Harbor Symp. Ouant. Biol. 53:649-655.
-
(1988)
Cold Spring Harbor Symp. Ouant. Biol.
, vol.53
, pp. 649-655
-
-
Wigler, M.1
Field, J.2
Powers, S.3
Broek, D.4
Toda, T.5
Cameron, S.6
Nikawa, J.7
Michaeli, T.8
Colicelli, J.9
Ferguson, K.10
-
87
-
-
0346222463
-
DNA-mediated transfer of the adenine phosphoribososyltransferase locus into mammalian cells
-
Wigler, M., A. Pellicer, S. Silverstein, R. Axel, G. Urlaub, and L. Chasin. 1979. DNA-mediated transfer of the adenine phosphoribososyltransferase locus into mammalian cells. Proc. Natl. Acad. Sci. USA 76:1373-1376.
-
(1979)
Proc. Natl. Acad. Sci. USA
, vol.76
, pp. 1373-1376
-
-
Wigler, M.1
Pellicer, A.2
Silverstein, S.3
Axel, R.4
Urlaub, G.5
Chasin, L.6
-
88
-
-
3142532865
-
Missing links between receptors and Ras
-
Williams, L. T. 1992. Missing links between receptors and Ras. Curr. Opin. Cell Biol. 2:601-603.
-
(1992)
Curr. Opin. Cell Biol.
, vol.2
, pp. 601-603
-
-
Williams, L.T.1
-
89
-
-
0027337248
-
ras proteins bind to the amino-terminal regulatory domain of c-Raf-1
-
ras proteins bind to the amino-terminal regulatory domain of c-Raf-1. Nature (London) 364:308-313.
-
(1993)
Nature (London)
, vol.364
, pp. 308-313
-
-
Zhang, X.1
Settleman, J.2
Kyriakis, J.M.3
Takeuchi-Suzuki, E.4
Elledge, S.J.5
Marshall, M.S.6
Bruder, J.T.7
Rapp, U.R.8
Avruch, J.9
-
90
-
-
0028329630
-
Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues
-
Zheng, C.-F., and K.-L. Guan. 1994. Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues. EMBO J. 13:1123-1131.
-
(1994)
EMBO J.
, vol.13
, pp. 1123-1131
-
-
Zheng, C.-F.1
Guan, K.-L.2
|