Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

Nature

Volumn 414, Issue 6863, 2001, Pages 514-521

  Nash, Piers ^a   Tang, Xiaojing ^a   Orlicky, Stephen ^a   Chen, Qinghua ^b   Gertler, Frank B ^c   Mendenhall, Michael D ^b   Sicheri, Frank ^a,d   Pawson, Tony ^a,d   Tyers, Mike ^a,d  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF KENTUCKY   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DEGRADATION; ENZYME INHIBITION; PROTEINS;

PHOSPHORYLATION;

DNA;

CYCLIN DEPENDENT KINASE INHIBITOR; LIGASE; UBIQUITIN;

DNA; PROTEIN;

ARTICLE; BINDING AFFINITY; CELL CYCLE G1 PHASE; DNA REPLICATION; ENZYME PHOSPHORYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION;

BINDING SITES; CELL CYCLE; CELL CYCLE PROTEINS; CONSENSUS SEQUENCE; DNA REPLICATION; DNA, FUNGAL; ENZYME INHIBITORS; F-BOX PROTEINS; FUNGAL PROTEINS; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE PROTEINS; SUBSTRATE SPECIFICITY; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 0035969559     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35107009     Document Type: Article

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