Degradation of Cdc25A by β-TrCP during S phase and in response to DNA damage

Nature

Volumn 426, Issue 6962, 2003, Pages 87-91

  Busino, Luca ^a   Donzelli, Maddalena ^a   Chiesa, Massimo ^a   Guardavaccaro, Daniele ^b   Ganoth, Dvora ^c   Dorrello, N Valerio ^b   Hershko, Avram ^c   Pagano, Michele ^b   Draetta, Giulio F ^a  

^a EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; DEGRADATION; DNA; IONIZING RADIATION; PROTEINS; RNA;

PHOSPHORYLATION;

ENZYME KINETICS;

ATM PROTEIN; ATR PROTEIN; CYCLIN DEPENDENT KINASE; PROTEIN; PROTEIN BETA TRCP; PROTEIN KINASE; PROTEIN TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG;

DNA;

ARTICLE; CELL CYCLE; CELL CYCLE S PHASE; CONTROLLED STUDY; DEPHOSPHORYLATION; DNA DAMAGE; DNA SYNTHESIS; DOWN REGULATION; ENZYME DEGRADATION; HUMAN; HUMAN CELL; IONIZING RADIATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BETA-TRANSDUCIN REPEAT-CONTAINING PROTEINS; BINDING SITES; CDC25 PHOSPHATASE; DNA DAMAGE; HELA CELLS; HUMANS; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN BINDING; RADIATION, IONIZING; S PHASE; UBIQUITIN;

EID: 0242497228     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature02082     Document Type: Article

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