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Volumn 58, Issue 32, 2002, Pages 6367-6372

Separation of Cdc25 dual specificity phosphatase inhibition and DNA cleaving activities in a focused library of analogs of the antitumor antibiotic Dnacin

(4) Wipf, Peter a Hopkins, Corey R a Phillips, Eleanor O b Lazo, John S b

a UNIVERSITY OF PITTSBURGH (United States)

b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE (United States)

Author keywords

Cdc25; DNA cleavage; Dnacin; Dual specificity phosphatase inhibitors; Natural product library; PTP1B; SAR; Tyrosine phosphatase; VHR

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; DNA; PROTEIN KINASE; PROTEIN TYROSINE PHOSPHATASE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; ASYMMETRIC SYNTHESIS; DNA CLEAVAGE; DRUG SPECIFICITY; ENZYME ACTIVITY; ENZYME INHIBITION; EVALUATION; GENE TARGETING; PRIORITY JOURNAL;

EID: 0037026007 PISSN: 00404020 EISSN: None Source Type: Journal
DOI: 10.1016/S0040-4020(02)00636-1 Document Type: Article

Times cited : (18)

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