-
1
-
-
0035895505
-
The sequence of the human genome
-
Venter J.C., et al. The sequence of the human genome. Science. 291:2001;1304-1351.
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
-
2
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
Lander E.S., et al. Initial sequencing and analysis of the human genome. Nature. 409:2001;860-921.
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
-
3
-
-
10244239321
-
Life with 6000 genes
-
Goffeau A., et al. Life with 6000 genes. Science. 274:1996;546-567.
-
(1996)
Science
, vol.274
, pp. 546-567
-
-
Goffeau, A.1
-
4
-
-
0033604566
-
Large-scale analysis of the yeast genome by transposon tagging and gene disruption
-
Ross-Macdonald P., et al. Large-scale analysis of the yeast genome by transposon tagging and gene disruption. Nature. 402:1999;413-418.
-
(1999)
Nature
, vol.402
, pp. 413-418
-
-
Ross-Macdonald, P.1
-
5
-
-
0035860499
-
Global analysis of protein activities using proteome chips
-
Zhu H., et al. Global analysis of protein activities using proteome chips. Science. 293:2001;2101-2105.
-
(2001)
Science
, vol.293
, pp. 2101-2105
-
-
Zhu, H.1
-
6
-
-
0037087575
-
Subcellular localization of the yeast proteome
-
Kumar A., et al. Subcellular localization of the yeast proteome. Genes Dev. 16:2002;707-719.
-
(2002)
Genes Dev.
, vol.16
, pp. 707-719
-
-
Kumar, A.1
-
7
-
-
0037059461
-
A combined experimental and computational strategy to define protein interaction networks for peptide recognition modules
-
Tong A.H., et al. A combined experimental and computational strategy to define protein interaction networks for peptide recognition modules. Science. 295:2002;321-324.
-
(2002)
Science
, vol.295
, pp. 321-324
-
-
Tong, A.H.1
-
8
-
-
0034628508
-
A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae
-
Uetz P., et al. A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature. 403:2000;623-627.
-
(2000)
Nature
, vol.403
, pp. 623-627
-
-
Uetz, P.1
-
9
-
-
0033669189
-
A network of protein-protein interactions in yeast
-
Schwikowski B., et al. A network of protein-protein interactions in yeast. Nat. Biotechnol. 18:2000;1257-1261.
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 1257-1261
-
-
Schwikowski, B.1
-
10
-
-
0037050004
-
Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry
-
Ho Y., et al. Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 415:2002;180-183.
-
(2002)
Nature
, vol.415
, pp. 180-183
-
-
Ho, Y.1
-
11
-
-
0037050026
-
Functional organization of the yeast proteome by systematic analysis of protein complexes
-
Gavin A.C., et al. Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature. 415:2002;141-147.
-
(2002)
Nature
, vol.415
, pp. 141-147
-
-
Gavin, A.C.1
-
12
-
-
0014027005
-
Cross-reactions of antisera against the terminal amino acid and dipeptide of tobacco mosaic virus
-
Anderer F.A., Schlumberger H.D. Cross-reactions of antisera against the terminal amino acid and dipeptide of tobacco mosaic virus. Biochim. Biophys. Acta. 115:1966;222-224.
-
(1966)
Biochim. Biophys. Acta
, vol.115
, pp. 222-224
-
-
Anderer, F.A.1
Schlumberger, H.D.2
-
13
-
-
0026579897
-
Genetic immunization is a simple method for eliciting an immune response
-
Tang D.-C., et al. Genetic immunization is a simple method for eliciting an immune response. Nature. 356:1992;152-154.
-
(1992)
Nature
, vol.356
, pp. 152-154
-
-
Tang, D.-C.1
-
14
-
-
0016756272
-
Continuous cultures of fused cells secreting antibody of predefined specificity
-
Kohler G., Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature. 256:1975;495-497.
-
(1975)
Nature
, vol.256
, pp. 495-497
-
-
Kohler, G.1
Milstein, C.2
-
15
-
-
0024991625
-
Peptides on phage: A vast library of peptides for identifying ligands
-
Cwirla S.E., et al. Peptides on phage: a vast library of peptides for identifying ligands. Proc. Natl. Acad. Sci. U. S. A. 87:1990;6378-6382.
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 6378-6382
-
-
Cwirla, S.E.1
-
16
-
-
0025112794
-
Searching for peptide ligands with an epitope library
-
Scott J.K., Smith G.P. Searching for peptide ligands with an epitope library. Science. 249:1990;386-390.
-
(1990)
Science
, vol.249
, pp. 386-390
-
-
Scott, J.K.1
Smith, G.P.2
-
17
-
-
0027287466
-
An M13 phage library displaying random 38-amino-acid peptides as a source of novel sequences with affinity to selected targets
-
Kay B.K., et al. An M13 phage library displaying random 38-amino-acid peptides as a source of novel sequences with affinity to selected targets. Gene. 128:1993;59-65.
-
(1993)
Gene
, vol.128
, pp. 59-65
-
-
Kay, B.K.1
-
18
-
-
0025226085
-
Phage antibodies: Filamentous phage displaying antibody variable domains
-
McCafferty J., et al. Phage antibodies: filamentous phage displaying antibody variable domains. Nature. 348:1990;552-554.
-
(1990)
Nature
, vol.348
, pp. 552-554
-
-
McCafferty, J.1
-
19
-
-
0035957011
-
Antibodies to human fetal erythroid cells from a nonimmune phage antibody library
-
Huie M.A., et al. Antibodies to human fetal erythroid cells from a nonimmune phage antibody library. Proc. Natl. Acad. Sci. U. S. A. 98:2001;2682-2687.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 2682-2687
-
-
Huie, M.A.1
-
20
-
-
9344223986
-
Human antibodies with sub-nanomolar affinities isolated from a large non-immunised phage display library
-
Vaughan T.J., et al. Human antibodies with sub-nanomolar affinities isolated from a large non-immunised phage display library. Nat. Biotechnol. 14:1996;309-314.
-
(1996)
Nat. Biotechnol.
, vol.14
, pp. 309-314
-
-
Vaughan, T.J.1
-
21
-
-
0033987925
-
Exploiting recombination in single bacteria to make large phage antibody libraries
-
Sblattero D., Bradbury A. Exploiting recombination in single bacteria to make large phage antibody libraries. Nat. Biotechnol. 18:2000;75-80.
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 75-80
-
-
Sblattero, D.1
Bradbury, A.2
-
22
-
-
0033603596
-
A large non-immunized human Fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies
-
de Haard H.J., et al. A large non-immunized human Fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies. J. Biol. Chem. 274:1999;18218-18230.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 18218-18230
-
-
De Haard, H.J.1
-
23
-
-
13144261717
-
Efficient construction of a large nonimmune phage antibody library; The production of panels of high affinity human single-chain antibodies to protein antigens
-
Sheets M.D., et al. Efficient construction of a large nonimmune phage antibody library; the production of panels of high affinity human single-chain antibodies to protein antigens. Proc. Natl. Acad. Sci. U. S. A. 95:1998;6157-6162.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 6157-6162
-
-
Sheets, M.D.1
-
24
-
-
0034635335
-
Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides
-
Knappik A., et al. Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides. J. Mol. Biol. 296:2000;57-86.
-
(2000)
J. Mol. Biol.
, vol.296
, pp. 57-86
-
-
Knappik, A.1
-
25
-
-
0027136111
-
Affinity maturation of human growth hormone by monovalent phage display
-
Lowman H.B., Wells J.A. Affinity maturation of human growth hormone by monovalent phage display. J. Mol. Biol. 234:1993;564-578.
-
(1993)
J. Mol. Biol.
, vol.234
, pp. 564-578
-
-
Lowman, H.B.1
Wells, J.A.2
-
26
-
-
0030976150
-
Bacteriophage display and discovery of peptide leads for drug development
-
Lowman H.B. Bacteriophage display and discovery of peptide leads for drug development. Annu. Rev. Biophys. Biomol. Struct. 26:1997;401-424.
-
(1997)
Annu. Rev. Biophys. Biomol. Struct.
, vol.26
, pp. 401-424
-
-
Lowman, H.B.1
-
27
-
-
0031812594
-
Antibody phage display technology and its applications
-
Hoogenboom H.R., et al. Antibody phage display technology and its applications. Immunotechnology. 4:1998;1-20.
-
(1998)
Immunotechnology
, vol.4
, pp. 1-20
-
-
Hoogenboom, H.R.1
-
28
-
-
0029011238
-
The use of phage display in neurobiology
-
Bradbury A., Cattaneo A. The use of phage display in neurobiology. Trends Neurosci. 18:1995;243-249.
-
(1995)
Trends Neurosci.
, vol.18
, pp. 243-249
-
-
Bradbury, A.1
Cattaneo, A.2
-
29
-
-
0026594374
-
Transport and anchoring of β-lactamase to the external surfaceof Escherichia coli
-
Francisco J.A., et al. Transport and anchoring of β-lactamase to the external surfaceof Escherichia coli. Proc. Natl. Acad. Sci. U. S. A. 89:1992;2713-2717.
-
(1992)
Proc. Natl. Acad. Sci. U. S. A.
, vol.89
, pp. 2713-2717
-
-
Francisco, J.A.1
-
30
-
-
0030994634
-
Yeast surface display for screening combinatorial polypeptide libraries
-
Boder E.T., Wittrup K.D. Yeast surface display for screening combinatorial polypeptide libraries. Nat. Biotechnol. 15:1997;553-557.
-
(1997)
Nat. Biotechnol.
, vol.15
, pp. 553-557
-
-
Boder, E.T.1
Wittrup, K.D.2
-
31
-
-
0030974119
-
In vitro selection and evolution of functional proteins by using ribosome display
-
Hanes J., Plückthun A. In vitro selection and evolution of functional proteins by using ribosome display. Proc. Natl. Acad. Sci. U. S. A. 94:1997;4937-4942.
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 4937-4942
-
-
Hanes, J.1
Plückthun, A.2
-
32
-
-
0030817279
-
RNA-peptide fusions for the in vitro selection of peptides and proteins
-
Roberts R.W., Szostak J.W. RNA-peptide fusions for the in vitro selection of peptides and proteins. Proc. Natl. Acad. Sci. U. S. A. 94:1997;12297-12302.
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 12297-12302
-
-
Roberts, R.W.1
Szostak, J.W.2
-
33
-
-
0024406857
-
A novel genetic system to detect protein-protein interactions
-
Fields S., Song O. A novel genetic system to detect protein-protein interactions. Nature. 340:1989;245-246.
-
(1989)
Nature
, vol.340
, pp. 245-246
-
-
Fields, S.1
Song, O.2
-
34
-
-
0032977886
-
An in vivo library-versus-library selection of optimized protein-protein interactions
-
Pelletier J.N., et al. An in vivo library-versus-library selection of optimized protein-protein interactions. Nat. Biotechnol. 17:1999;683-690.
-
(1999)
Nat. Biotechnol.
, vol.17
, pp. 683-690
-
-
Pelletier, J.N.1
-
35
-
-
0032716364
-
Selection of antibodies for intracellular function using a two-hybrid in vivo system
-
Visintin M., et al. Selection of antibodies for intracellular function using a two-hybrid in vivo system. Proc. Natl. Acad. Sci. U. S. A. 96:1999;11723-11728.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 11723-11728
-
-
Visintin, M.1
-
36
-
-
0035941063
-
Antigen-independent selection of stable intracellular single-chain antibodies
-
Auf-der-Maur A., et al. Antigen-independent selection of stable intracellular single-chain antibodies. FEBS Lett. 508:2001;407-412.
-
(2001)
FEBS Lett.
, vol.508
, pp. 407-412
-
-
Auf-der-Maur, A.1
-
37
-
-
0035957521
-
Fast selection of antibodies without antigen purification: Adaptation of the protein fragment complementation assay to select antigen-antibody pairs
-
Mossner E., et al. Fast selection of antibodies without antigen purification: adaptation of the protein fragment complementation assay to select antigen-antibody pairs. J. Mol. Biol. 308:2001;115-122.
-
(2001)
J. Mol. Biol.
, vol.308
, pp. 115-122
-
-
Mossner, E.1
-
38
-
-
0033865190
-
Engineered protein scaffolds for molecular recognition
-
Skerra A. Engineered protein scaffolds for molecular recognition. J. Mol. Recognit. 13:2000;167-187.
-
(2000)
J. Mol. Recognit.
, vol.13
, pp. 167-187
-
-
Skerra, A.1
-
39
-
-
0026699293
-
Selection of phage antibodies by binding affinity: Mimicking affinity maturation
-
Hawkins R.E., et al. Selection of phage antibodies by binding affinity: mimicking affinity maturation. J. Mol. Biol. 226:1992;889-896.
-
(1992)
J. Mol. Biol.
, vol.226
, pp. 889-896
-
-
Hawkins, R.E.1
-
40
-
-
0027425230
-
Production and fluorescence-activated cell sorting of Escherichia coli expressing a functional antibody fragment on the external surface
-
Francisco J.A., et al. Production and fluorescence-activated cell sorting of Escherichia coli expressing a functional antibody fragment on the external surface. Proc. Natl. Acad. Sci. U. S. A. 90:1993;10444-10448.
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 10444-10448
-
-
Francisco, J.A.1
-
41
-
-
0034425742
-
Antibody arrays for high-throughput screening of antibody-antigen interactions
-
de Wildt R.M., et al. Antibody arrays for high-throughput screening of antibody-antigen interactions. Nat. Biotechnol. 18:2000;989-994.
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 989-994
-
-
De Wildt, R.M.1
-
42
-
-
0031663081
-
Antibody affinity maturation using bacterial surface display
-
Daugherty P.S., et al. Antibody affinity maturation using bacterial surface display. Protein Eng. 11:1998;825-832.
-
(1998)
Protein Eng.
, vol.11
, pp. 825-832
-
-
Daugherty, P.S.1
-
43
-
-
0034718615
-
Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity
-
Boder E.T., et al. Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity. Proc. Natl. Acad. Sci. U. S. A. 97:2000;10701-10705.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 10701-10705
-
-
Boder, E.T.1
-
44
-
-
0033536626
-
Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency
-
Shusta E.V., et al. Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency. J. Mol. Biol. 292:1999;949-956.
-
(1999)
J. Mol. Biol.
, vol.292
, pp. 949-956
-
-
Shusta, E.V.1
-
45
-
-
0037318058
-
Flow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library
-
Feldhaus M.J., et al. Flow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library. Nat. Biotechnol. 21:2003;163-170.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 163-170
-
-
Feldhaus, M.J.1
-
46
-
-
0032993160
-
Single-chain variable fragments selected on the 57-76 p21Ras neutralising epitope from phage antibody libraries recognise the native protein
-
Persic L., et al. Single-chain variable fragments selected on the 57-76 p21Ras neutralising epitope from phage antibody libraries recognise the native protein. FEBS Lett. 443:1999;112-116.
-
(1999)
FEBS Lett.
, vol.443
, pp. 112-116
-
-
Persic, L.1
-
47
-
-
0037056219
-
Target validation for genomics using peptide-specific phage antibodies: A study of five gene products overexpressed in colorectal cancer
-
Van Beijnum J.R., et al. Target validation for genomics using peptide-specific phage antibodies: a study of five gene products overexpressed in colorectal cancer. Int. J. Cancer. 101:2002;118-127.
-
(2002)
Int. J. Cancer
, vol.101
, pp. 118-127
-
-
Van Beijnum, J.R.1
-
48
-
-
0036303521
-
Towards proteome-wide production of monoclonal antibody by phage display
-
Liu B., et al. Towards proteome-wide production of monoclonal antibody by phage display. J. Mol. Biol. 315:2002;1063-1073.
-
(2002)
J. Mol. Biol.
, vol.315
, pp. 1063-1073
-
-
Liu, B.1
-
49
-
-
0035715878
-
In vivo recombination as a tool to generate molecular diversity in phage antibody libraries
-
Sblattero D., et al. In vivo recombination as a tool to generate molecular diversity in phage antibody libraries. J. Biotechnol. 74:2001;303-315.
-
(2001)
J. Biotechnol.
, vol.74
, pp. 303-315
-
-
Sblattero, D.1
-
50
-
-
0028291823
-
Isolation of high affinity human antibodies directly from large synthetic repertoires
-
Griffiths A.D., et al. Isolation of high affinity human antibodies directly from large synthetic repertoires. EMBO J. 13:1994;3245-3260.
-
(1994)
EMBO J.
, vol.13
, pp. 3245-3260
-
-
Griffiths, A.D.1
-
51
-
-
0029564921
-
CDR walking mutagenesis for the affinity maturation of a potent human anti-HIV-1 antibody into the picomolar range
-
Yang W.P., et al. CDR walking mutagenesis for the affinity maturation of a potent human anti-HIV-1 antibody into the picomolar range. J. Mol. Biol. 254:1995;392-403.
-
(1995)
J. Mol. Biol.
, vol.254
, pp. 392-403
-
-
Yang, W.P.1
-
52
-
-
0030575802
-
Isolation of picomolar affinity anti-c-erB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site
-
Schier R., et al. Isolation of picomolar affinity anti-c-erB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site. J. Mol. Biol. 263:1996;551-567.
-
(1996)
J. Mol. Biol.
, vol.263
, pp. 551-567
-
-
Schier, R.1
-
53
-
-
0029927859
-
Affinity maturation of a high-affinity human monoclonal antibody against the third hypervariable loop of human immunodeficiency virus: Use of phage display to improve affinity and broaden strain reactivity
-
Thompson J., et al. Affinity maturation of a high-affinity human monoclonal antibody against the third hypervariable loop of human immunodeficiency virus: use of phage display to improve affinity and broaden strain reactivity. J. Mol. Biol. 256:1996;77-88.
-
(1996)
J. Mol. Biol.
, vol.256
, pp. 77-88
-
-
Thompson, J.1
-
54
-
-
0026528230
-
Miniantibodies: Use of amphipathic helices to produce functional, flexibly linked dimeric FV fragments with high avidity in Escherichia coli
-
Pack P., Pluckthun A. Miniantibodies: use of amphipathic helices to produce functional, flexibly linked dimeric FV fragments with high avidity in Escherichia coli. Biochemistry. 31:1992;1579-1584.
-
(1992)
Biochemistry
, vol.31
, pp. 1579-1584
-
-
Pack, P.1
Pluckthun, A.2
-
55
-
-
0035400341
-
Antibodies in haystacks: How selection strategy influences the outcome of selection from molecular diversity libraries
-
Lou J., et al. Antibodies in haystacks: how selection strategy influences the outcome of selection from molecular diversity libraries. J. Immunol. Methods. 253:2001;233-242.
-
(2001)
J. Immunol. Methods
, vol.253
, pp. 233-242
-
-
Lou, J.1
-
56
-
-
0030916353
-
Two amino acid mutations in an anti-human CD3 single chain Fv antibody fragment that affect the yield on bacterial secretion but not the affinity
-
Kipriyanov S.M., et al. Two amino acid mutations in an anti-human CD3 single chain Fv antibody fragment that affect the yield on bacterial secretion but not the affinity. Protein Eng. 10:1997;445-453.
-
(1997)
Protein Eng.
, vol.10
, pp. 445-453
-
-
Kipriyanov, S.M.1
-
57
-
-
0029017297
-
A point mutation in a murine immunoglobulin V-region strongly influences the antibody yield in Escherichia coli
-
Duenas M., et al. A point mutation in a murine immunoglobulin V-region strongly influences the antibody yield in Escherichia coli. Gene. 158:1995;61-66.
-
(1995)
Gene
, vol.158
, pp. 61-66
-
-
Duenas, M.1
-
58
-
-
0030832921
-
Use of mutator cells as a means for increasing production levels of a recombinant antibody directed against hepatitis B
-
Coia G., et al. Use of mutator cells as a means for increasing production levels of a recombinant antibody directed against hepatitis B. Gene. 201:1997;203-209.
-
(1997)
Gene
, vol.201
, pp. 203-209
-
-
Coia, G.1
-
59
-
-
0035427605
-
High-throughput generation and engineering of recombinant human antibodies
-
Krebs B., et al. High-throughput generation and engineering of recombinant human antibodies. J. Immunol. Methods. 254:2001;67-84.
-
(2001)
J. Immunol. Methods
, vol.254
, pp. 67-84
-
-
Krebs, B.1
-
60
-
-
0035854543
-
A semi-synthetic repertoire of intrinsically stable antibody fragments derived from a single-framework scaffold
-
Desiderio A., et al. A semi-synthetic repertoire of intrinsically stable antibody fragments derived from a single-framework scaffold. J. Mol. Biol. 310:2001;603-615.
-
(2001)
J. Mol. Biol.
, vol.310
, pp. 603-615
-
-
Desiderio, A.1
-
61
-
-
0034244316
-
By-passing selection: Direct screening for antibody-antigen interactions using protein arrays
-
Holt L.J., et al. By-passing selection: direct screening for antibody-antigen interactions using protein arrays. Nucleic Acids Res. 28:2000;E72.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 72
-
-
Holt, L.J.1
-
62
-
-
0033748716
-
Yeast surface display for directed evolution of protein expression, affinity, and stability
-
Boder E.T., Wittrup K.D. Yeast surface display for directed evolution of protein expression, affinity, and stability. Methods Enzymol. 328:2000;430-444.
-
(2000)
Methods Enzymol.
, vol.328
, pp. 430-444
-
-
Boder, E.T.1
Wittrup, K.D.2
-
63
-
-
0031559943
-
In vitro virus: Bonding of mRNA bearing puromycin at the 3′-terminal end to the C-terminal end of its encoded protein on the ribosome in vitro
-
Nemoto N., et al. In vitro virus: bonding of mRNA bearing puromycin at the 3′-terminal end to the C-terminal end of its encoded protein on the ribosome in vitro. FEBS Lett. 414:1997;405-408.
-
(1997)
FEBS Lett.
, vol.414
, pp. 405-408
-
-
Nemoto, N.1
-
64
-
-
0031574037
-
Antibody-ribosome-mRNA (ARM) complexes as efficient selection particles for in vitro display and evolution of antibody combining sites
-
He M., Taussig M.J. Antibody-ribosome-mRNA (ARM) complexes as efficient selection particles for in vitro display and evolution of antibody combining sites. Nucleic Acids Res. 25:1997;5132-5134.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 5132-5134
-
-
He, M.1
Taussig, M.J.2
-
65
-
-
0033664270
-
Picomolar affinity antibodies from a fully synthetic naive library selected and evolved by ribosome display
-
Hanes J., et al. Picomolar affinity antibodies from a fully synthetic naive library selected and evolved by ribosome display. Nat. Biotechnol. 18:2000;1287-1292.
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 1287-1292
-
-
Hanes, J.1
-
66
-
-
0033733267
-
Selecting and evolving functional proteins in vitro by ribosome display
-
Hanes J., et al. Selecting and evolving functional proteins in vitro by ribosome display. Methods Enzymol. 328:2000;404-430.
-
(2000)
Methods Enzymol.
, vol.328
, pp. 404-430
-
-
Hanes, J.1
-
67
-
-
0028110130
-
DNA shuffling by random fragmentation and reassembly: In vitro recombination for molecular evolution
-
Stemmer W.P. DNA shuffling by random fragmentation and reassembly: in vitro recombination for molecular evolution. Proc. Natl. Acad. Sci. U. S. A. 91:1994;10747-10751.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 10747-10751
-
-
Stemmer, W.P.1
-
68
-
-
0037029131
-
A bilayer cell-free protein synthesis system for high-throughput screening of gene products
-
Sawasaki T., et al. A bilayer cell-free protein synthesis system for high-throughput screening of gene products. FEBS Lett. 514:2002;102-105.
-
(2002)
FEBS Lett.
, vol.514
, pp. 102-105
-
-
Sawasaki, T.1
-
69
-
-
18544397601
-
Directed evolution of high-affinity antibody mimics using mRNA display
-
Xu L., et al. Directed evolution of high-affinity antibody mimics using mRNA display. Chem. Biol. 9:2002;933-942.
-
(2002)
Chem. Biol.
, vol.9
, pp. 933-942
-
-
Xu, L.1
-
70
-
-
0034957669
-
High-throughput proteomics: Protein expression and purification in the postgenomic world
-
Lesley S.A. High-throughput proteomics: protein expression and purification in the postgenomic world. Protein Expr. Purif. 22:2001;159-164.
-
(2001)
Protein Expr. Purif.
, vol.22
, pp. 159-164
-
-
Lesley, S.A.1
-
71
-
-
0037015054
-
Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline
-
Lesley S.A., et al. Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proc. Natl. Acad. Sci. U. S. A. 99:2002;11664-11669.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 11664-11669
-
-
Lesley, S.A.1
-
72
-
-
0036299049
-
The intracellular antibody capture technology (IACT): Towards a consensus sequence for intracellular antibodies
-
Visintin M., et al. The intracellular antibody capture technology (IACT): towards a consensus sequence for intracellular antibodies. J. Mol. Biol. 317:2002;73-83.
-
(2002)
J. Mol. Biol.
, vol.317
, pp. 73-83
-
-
Visintin, M.1
-
73
-
-
0036299007
-
Intracellular antibody capture technology: Application to selection of intracellular antibodies recognising the BCR-ABL oncogenic protein
-
Tse E., et al. Intracellular antibody capture technology: application to selection of intracellular antibodies recognising the BCR-ABL oncogenic protein. J. Mol. Biol. 317:2002;85-94.
-
(2002)
J. Mol. Biol.
, vol.317
, pp. 85-94
-
-
Tse, E.1
-
74
-
-
0034691202
-
A bacterial two-hybrid selection system for studying protein-DNA and protein-protein interactions
-
Joung J.K., et al. A bacterial two-hybrid selection system for studying protein-DNA and protein-protein interactions. Proc. Natl. Acad. Sci. U. S. A. 97:2000;7382-7387.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 7382-7387
-
-
Joung, J.K.1
-
75
-
-
0032510783
-
A bacterial two-hybrid system based on a reconstituted signal transduction pathway
-
Karimova G., et al. A bacterial two-hybrid system based on a reconstituted signal transduction pathway. Proc. Natl. Acad. Sci. U. S. A. 95:1998;5752-5756.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 5752-5756
-
-
Karimova, G.1
-
76
-
-
0032032533
-
Conversion of the omega subunit of Escherichia coli RNA polymerase into a transcriptional activator or an activation target
-
Dove S.L., Hochschild A. Conversion of the omega subunit of Escherichia coli RNA polymerase into a transcriptional activator or an activation target. Genes Dev. 12:1998;745-754.
-
(1998)
Genes Dev.
, vol.12
, pp. 745-754
-
-
Dove, S.L.1
Hochschild, A.2
-
77
-
-
0030907304
-
Activation of prokaryotic transcription through arbitrary protein-protein contacts
-
Dove S.L., et al. Activation of prokaryotic transcription through arbitrary protein-protein contacts. Nature. 386:1997;627-630.
-
(1997)
Nature
, vol.386
, pp. 627-630
-
-
Dove, S.L.1
-
78
-
-
0035424708
-
Exploring protein interactions by interaction-induced folding of proteins from complementary peptide fragments
-
Michnick S.W. Exploring protein interactions by interaction-induced folding of proteins from complementary peptide fragments. Curr. Opin. Struct. Biol. 11:2001;472-477.
-
(2001)
Curr. Opin. Struct. Biol.
, vol.11
, pp. 472-477
-
-
Michnick, S.W.1
-
79
-
-
0035984722
-
Beta-lactamase protein fragment complementation assays as in vivo and in vitro sensors of protein-protein interactions
-
Galarneau A., et al. Beta-lactamase protein fragment complementation assays as in vivo and in vitro sensors of protein-protein interactions. Nat. Biotechnol. 20:2002;619-622.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 619-622
-
-
Galarneau, A.1
-
80
-
-
0035793208
-
Stability engineering of antibody single-chain Fv fragments
-
Worn A., Pluckthun A. Stability engineering of antibody single-chain Fv fragments. J. Mol. Biol. 305:2001;989-1010.
-
(2001)
J. Mol. Biol.
, vol.305
, pp. 989-1010
-
-
Worn, A.1
Pluckthun, A.2
-
81
-
-
0344813702
-
Antibody scFv fragments without disulfide bonds made by molecular evolution
-
Proba K., et al. Antibody scFv fragments without disulfide bonds made by molecular evolution. J. Mol. Biol. 275:1998;245-253.
-
(1998)
J. Mol. Biol.
, vol.275
, pp. 245-253
-
-
Proba, K.1
-
82
-
-
0033584889
-
Selection for improved protein stability by phage display
-
Jung S., et al. Selection for improved protein stability by phage display. J. Mol. Biol. 294:1999;163-180.
-
(1999)
J. Mol. Biol.
, vol.294
, pp. 163-180
-
-
Jung, S.1
-
83
-
-
0032479180
-
Expression of an antibody fragment at high levels in the bacterial cytoplasm
-
Martineau P., et al. Expression of an antibody fragment at high levels in the bacterial cytoplasm. J. Mol. Biol. 280:1998;117-127.
-
(1998)
J. Mol. Biol.
, vol.280
, pp. 117-127
-
-
Martineau, P.1
-
85
-
-
0033520452
-
Intrabody construction and expression. II. A synthetic catalytic Fv fragment
-
Ohage E.C., et al. Intrabody construction and expression. II. A synthetic catalytic Fv fragment. J. Mol. Biol. 291:1999;1129-1134.
-
(1999)
J. Mol. Biol.
, vol.291
, pp. 1129-1134
-
-
Ohage, E.C.1
-
86
-
-
0028111743
-
Sequence statistics reliably predict stabilizing mutations in a protein domain
-
Steipe B., et al. Sequence statistics reliably predict stabilizing mutations in a protein domain. J. Mol. Biol. 240:1994;188-192.
-
(1994)
J. Mol. Biol.
, vol.240
, pp. 188-192
-
-
Steipe, B.1
-
87
-
-
0033520343
-
Intrabody construction and expression. I. The critical role of VL domain stability
-
Ohage E., Steipe B. Intrabody construction and expression. I. The critical role of VL domain stability. J. Mol. Biol. 291:1999;1119-1128.
-
(1999)
J. Mol. Biol.
, vol.291
, pp. 1119-1128
-
-
Ohage, E.1
Steipe, B.2
-
88
-
-
0032718607
-
Intrabody construction and expression III: Engineering hyperstable V(H) domains
-
Wirtz P., Steipe B. Intrabody construction and expression III: engineering hyperstable V(H) domains. Protein Sci. 8:1999;2245-2250.
-
(1999)
Protein Sci.
, vol.8
, pp. 2245-2250
-
-
Wirtz, P.1
Steipe, B.2
-
90
-
-
0035823143
-
Escherichia coli maltose-binding protein as a molecular chaperone for recombinant intracellular cytoplasmic single-chain antibodies
-
Bach H., et al. Escherichia coli maltose-binding protein as a molecular chaperone for recombinant intracellular cytoplasmic single-chain antibodies. J. Mol. Biol. 312:2001;79-93.
-
(2001)
J. Mol. Biol.
, vol.312
, pp. 79-93
-
-
Bach, H.1
-
91
-
-
0037172976
-
Isolation of receptor-ligand pairs by capture of long-lived multivalent interaction complexes
-
de Wildt R.M., et al. Isolation of receptor-ligand pairs by capture of long-lived multivalent interaction complexes. Proc. Natl. Acad. Sci. U. S. A. 99:2002;8530-8535.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 8530-8535
-
-
De Wildt, R.M.1
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