An in vivo library-versus-library selection of optimized protein- protein interactions

Nature Biotechnology

Volumn 17, Issue 7, 1999, Pages 683-690

  Pelletier, Joelle N ^a,b   Arndt, Katja M ^b   Plückthun, Andreas ^b   Michnick, Stephen W ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Coiled coil; Dihydrofolate reductase; Leucine zipper; Library screening; Library versus library; Protein fragment complementation assay; Protein protein interaction; Selection strategy; Trinucleotide

Indexed keywords

DIHYDROFOLATE REDUCTASE; LEUCINE ZIPPER PROTEIN; TRINUCLEOTIDE;

ARTICLE; BACTERIAL GROWTH; DIMERIZATION; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE LIBRARY; GENETIC COMPLEMENTATION; HYDROPHOBICITY; IN VIVO STUDY; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION;

ANIMALS; DIMERIZATION; ESCHERICHIA COLI; LEUCINE ZIPPERS; MICE; MUTATION; PEPTIDE FRAGMENTS; PEPTIDE LIBRARY; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT FUSION PROTEINS; TETRAHYDROFOLATE DEHYDROGENASE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MURINAE;

EID: 0032977886     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/10897     Document Type: Article

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