The PPARs and PXRs: Nuclear xenobiotic receptors that define novel hormone signaling pathways

Recent Progress in Hormone Research

Volumn 54, Issue , 1999, Pages 345-368

  Kliewer, Steven A ^a   Lehmann, Jürgen M ^a   Milburn, Michael V ^a   Willson, Timothy M ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ANTICONVULSIVE AGENT; ANTIFUNGAL AGENT; ANTIGESTAGEN; ANTILIPEMIC AGENT; ANTIRETROVIRUS AGENT; BARBITURIC ACID DERIVATIVE; BEZAFIBRATE; CLOFIBRATE; CLOTRIMAZOLE; CYTOCHROME P450; DEXAMETHASONE; ELTANOLONE; FATTY ACID; FENOFIBRATE; FIBRIC ACID DERIVATIVE; GLUCOCORTICOID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ICOSANOID; MEVINOLIN; MIFEPRISTONE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PHENOBARBITAL; PROGESTERONE; PROGESTERONE RECEPTOR; RIFAMPICIN; STEROID; THIAZOLIDINE DERIVATIVE; UNINDEXED DRUG; XENOBIOTIC AGENT;

ATHEROSCLEROSIS; CONFERENCE PAPER; DIABETES MELLITUS; DRUG MECHANISM; DRUG METABOLISM; HORMONE RECEPTOR INTERACTION; HUMAN; HYPERCHOLESTEROLEMIA; LIGAND BINDING; LIPID METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; SIGNAL TRANSDUCTION; XENOBIOTIC METABOLISM;

ANIMALS; HUMANS; NUCLEAR PROTEINS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; XENOBIOTICS;

EID: 0033395836     PISSN: 00799963     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (23)

1. Barnett, D., Craig, J.G., Robinson, D.S., and Perenna-Roberts, M. (1977). Br. J. Clin. Pharmacol. 4, 455-458.
2. Barwick, J.L., Quattrochi, L.C., Mills, A.S., Potenza, C., Tukey, R.H., and Guzelian, P.S. (1996). Molec. Pharmacol. 50, 10-16.
3. Blumberg, B., Kang, K., Bolado, J., Chen, H., Craig, A., Moreno, T., Umesono, K., Perlmann, T., DeRobertis, E., and Evans, R. (1998). Genes Devel. 12, 1269-1277.
4. Braissant, O., Foufelle, F., Scotto, C., Dauca, M., and Wahli, W. (1996). Endocrinology 137, 354-366.
5. Burger, H.-J., Schuetz, J.D., Schuetz, E.G., and Guzelian, P.S. (1992). Proc. Natl. Acad. Sci. U.S.A. 89, 2145-2149.
6. Chawla, A., Schwartz, E.J., Dimaculangan, D.D., and Lazar, M.A. (1994). Endocrinology 135, 798-800.
7. Chen, F., Law, S.W., and O'Malley, B.W. (1993). Biochem. Biophys. Res. Comm. 196, 671-677.
8. Cohen, B., Novick, D., and Rubinstein, M. (1996). Science 274, 1151-1152.
9. Desvergne, B., and Wahli, W. (1995). In "Inducible Gene Expression" (P. A. Baeuerle, ed.), pp. 142-176. Birkhauser, Boston.
10. Digby, J.E., Montague, C.T., Sewter, C.P., Sanders, L., Wilkison, W.O., O'Rahilly, S., and Prins, J.B. (1998). Diabetes 47, 138-141.
11. Dowell, P., Peterson, V., Zabriskie, T., and Leid, M. (1997). J. Biol. Chem. 272, 2013-2020.
12. Foellmi-Adams, L.A., Wyse, B.M., Herron, D., Nedergaard, J., and Kletzien, R.F. (1996). Biochem. Pharm. 52, 693-701.
13. Forman, B., Tontonoz, P., Chen, J., Brun, R., Spiegelman, B., and Evans, R. (1995). Cell 83, 803-812.
14. Forman, B.M., Chen, J., and Evans, R.M. (1997). Proc. Natl. Acad. Sci. U.S.A. 94, 4312-4317.
15. Göttlicher, M., Widmark, E., Li, Q., and Gustafsson, J.-A. (1992). Proc. Natl. Acad. Sci. U.S.A. 89, 4653-4657.
16. Greene, M.E., Blumberg, B., McBride, O.W., Yi, H.F., Kronquist, K., Kwan, K., Hsieh, L., Greene, G., and Nimer, S.D. (1995). Gene Expression 4, 281-299.
17. Grundy, S., and Denke, M. (1990). J. Lipid Res. 31, 1149-1172.
18. Guzelian, P.S. (1988). In "Microsomes and Drug Oxidations" (J.O. Miners, D.J. Birkett, R. Drew, and M. McManus, eds.), pp. 148-155. Taylor and Francis, London.
19. Hallakou, S., Doare, L., Foufelle, F., Kergoat, M., Guerre-Millo, M., Berthault, M.-F., Dugail, I., Morin, J., Auwerx, J., and Ferre, P. (1997). Diabetes 46, 1393-1399.
20. Hashimoto, H., Toide, K., Kitamura, R., Fujita, M., Tagawa, S., Itoh, S., and Kamataki, T. (1993). Eur. J. Biochem. 218, 585-595.
21. Hawke, R.L., Chapman, J.M., Winegar, D.A., Salisbury, J.A., Welch, R.M., Brown, A., Franzmann, K.W., and Sigel, C. (1997). J. Lipid Res. 38, 1189-1203.
22. Heyman, R.A., Mangelsdorf, D.J., Dyck, J.A., Stein, R., Eichele, G., Evans, R.M., and Thaller, C. (1992). Cell 68, 397-406.
23. Himms-Hagen, J. (1992). In "Obesity" (P. Bjorntorp and B.N. Brodoff, eds.), pp. 15-34. J.B. Lippincott Company, Philadelphia.