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Volumn 32, Issue 3, 1997, Pages 210-258

Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450;

EID: 0030935086     PISSN: 03125963     EISSN: None     Source Type: Journal    
DOI: 10.2165/00003088-199732030-00004     Document Type: Review
Times cited : (725)

References (681)
  • 2
    • 0029879648 scopus 로고    scopus 로고
    • Inhibition of sulfamethoxazole hydroxylamine formation by fluconazole in human liver microsomes and healthy volunteers
    • Mitra AK, Thummel KE, Kalhorn TF, et al. Inhibition of sulfamethoxazole hydroxylamine formation by fluconazole in human liver microsomes and healthy volunteers. Clin Pharmacol Trier 1996; 59: 332-40
    • (1996) Clin Pharmacol Trier , vol.59 , pp. 332-340
    • Mitra, A.K.1    Thummel, K.E.2    Kalhorn, T.F.3
  • 3
    • 0024347786 scopus 로고
    • Inhibition of human liver microsomal epoxide hydrolase by valproate and valpromide: In vitro/in vivo correlation
    • Kerr BM, Rettie AE, Eddy AC, et al. Inhibition of human liver microsomal epoxide hydrolase by valproate and valpromide: in vitro/in vivo correlation. Clin Pharmacol Ther 1989; 46: 82-93
    • (1989) Clin Pharmacol Ther , vol.46 , pp. 82-93
    • Kerr, B.M.1    Rettie, A.E.2    Eddy, A.C.3
  • 4
    • 0029914380 scopus 로고    scopus 로고
    • Warfarin-Fluconazole III: A rational approach to management of a metabolic ally based drug interaction
    • Kunze KL, Trager WF, Warfarin-Fluconazole III: a rational approach to management of a metabolic ally based drug interaction. Drug Metab Dispos 1996; 24: 429-35
    • (1996) Drug Metab Dispos , vol.24 , pp. 429-435
    • Kunze, K.L.1    Trager, W.F.2
  • 5
    • 0027440355 scopus 로고
    • Carbamazepine-valnoctamide interaction in epileptic patients: In vitro/in vivo correlation
    • Pisani F, Haj-Yehia A, Fazio A, et al. Carbamazepine-valnoctamide interaction in epileptic patients: In vitro/in vivo correlation. Epilepsia 1993; 34: 954-9
    • (1993) Epilepsia , vol.34 , pp. 954-959
    • Pisani, F.1    Haj-Yehia, A.2    Fazio, A.3
  • 6
    • 0027440418 scopus 로고
    • In vivo and in vitro correlation of microsomal epoxide hydrolase inhibition by progabide
    • Kroetz DL, Loiseau P, Guyot M, et al. In vivo and in vitro correlation of microsomal epoxide hydrolase inhibition by progabide. Clin Pharmacol Ther 1993; 54: 484-97
    • (1993) Clin Pharmacol Ther , vol.54 , pp. 484-497
    • Kroetz, D.L.1    Loiseau, P.2    Guyot, M.3
  • 7
    • 0028898816 scopus 로고
    • Inhibition of alprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: Comparison with other selective serotonin reuptake inhibitor antidepressants
    • von Moltke LL, Greenblatt DJ, Court MH, et al. Inhibition of alprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: comparison with other selective serotonin reuptake inhibitor antidepressants. J Clin Psychopharmacol 1995; 15: 125-31
    • (1995) J Clin Psychopharmacol , vol.15 , pp. 125-131
    • Von Moltke, L.L.1    Greenblatt, D.J.2    Court, M.H.3
  • 8
    • 0029950964 scopus 로고    scopus 로고
    • Prediction of in vivo drug disposition from in vitro data based on physiological pharmacokinetics
    • Iwatsubo T, Hirota N, Ooie T, et al. Prediction of in vivo drug disposition from in vitro data based on physiological pharmacokinetics. Biopharm Drug Dispos 1996; 17: 273-310
    • (1996) Biopharm Drug Dispos , vol.17 , pp. 273-310
    • Iwatsubo, T.1    Hirota, N.2    Ooie, T.3
  • 9
    • 0026778218 scopus 로고
    • Predictability of the in vivo metabolism of verapamil from in vitro data: Contribution of individual metabolic pathways and stereoseleclive aspects
    • Kroemer HK, Echizen H, Heidemann H, et al. Predictability of the in vivo metabolism of verapamil from in vitro data: contribution of individual metabolic pathways and stereoseleclive aspects. J Pharmacol Exp Ther 1992; 260: 1052-7
    • (1992) J Pharmacol Exp Ther , vol.260 , pp. 1052-1057
    • Kroemer, H.K.1    Echizen, H.2    Heidemann, H.3
  • 10
    • 0028820208 scopus 로고
    • Differentiation of absorption and first-pass gut and hepatic metabolism in humans: Studies with cyclosporine
    • Wu C-Y, Benet LZ, Herbert MF, et al. Differentiation of absorption and first-pass gut and hepatic metabolism in humans: studies with cyclosporine. Clin Pharmacol Ther 1995; 58: 492-7
    • (1995) Clin Pharmacol Ther , vol.58 , pp. 492-497
    • Wu, C.-Y.1    Benet, L.Z.2    Herbert, M.F.3
  • 11
    • 0028303820 scopus 로고
    • Plasma protein binding displacement interactions?: Why are they still regarded as clinically important?
    • Rolan PE. Plasma protein binding displacement interactions?: why are they still regarded as clinically important? Br J Clin Pharmacol 1994; 37: 125-8
    • (1994) Br J Clin Pharmacol , vol.37 , pp. 125-128
    • Rolan, P.E.1
  • 12
    • 0018363645 scopus 로고
    • Plasma protein displacement interactions are rarely of clinical importance
    • Sellers EM. Plasma protein displacement interactions are rarely of clinical importance. Pharmacology 1979; 18: 225-7
    • (1979) Pharmacology , vol.18 , pp. 225-227
    • Sellers, E.M.1
  • 13
    • 26444539817 scopus 로고
    • Genetic control of isoniazide metabolism in man
    • Price-Evans DA, Mainley KA, McKussick VA. Genetic control of isoniazide metabolism in man. BMJ 1960; 2: 485-91
    • (1960) BMJ , vol.2 , pp. 485-491
    • Price-Evans, D.A.1    Mainley, K.A.2    McKussick, V.A.3
  • 14
    • 0017695082 scopus 로고
    • Polymorphic hydroxylation of debrisoquin in man
    • Mahgoub A, Idle JR, Dring LG, et al. Polymorphic hydroxylation of debrisoquin in man. Lancet 1977; 11: 584-6
    • (1977) Lancet , vol.11 , pp. 584-586
    • Mahgoub, A.1    Idle, J.R.2    Dring, L.G.3
  • 16
    • 0010934844 scopus 로고
    • Family study of a genetically determined deficiency of mephenytoin hydroxylation in man
    • Kupper A, Desmond P, Schenker S, et al. Family study of a genetically determined deficiency of mephenytoin hydroxylation in man. Pharmacologist 1979; 21: 173
    • (1979) Pharmacologist , vol.21 , pp. 173
    • Kupper, A.1    Desmond, P.2    Schenker, S.3
  • 17
    • 0024236331 scopus 로고
    • The molecular biology of cytochrome P450
    • Gonzalez FJ. The molecular biology of cytochrome P450. Pharmacol Rev 1989; 40: 243-88
    • (1989) Pharmacol Rev , vol.40 , pp. 243-288
    • Gonzalez, F.J.1
  • 18
    • 0028237729 scopus 로고
    • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens, and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
    • Shimada T, Yamazaki H, Mimura M, et al. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens, and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther 1994; 270: 414-23
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 414-423
    • Shimada, T.1    Yamazaki, H.2    Mimura, M.3
  • 19
    • 0002769936 scopus 로고    scopus 로고
    • Pharmacokinetics: The dynamics of drug absorption, distribution, and elimination
    • Hardman JG, Limbird LE, Molinoff PB, et al., editors. New York (NY): McGraw-Hill
    • Benet LZ, Kroetz DL, Sheiner LB. Pharmacokinetics: the dynamics of drug absorption, distribution, and elimination. In: Hardman JG, Limbird LE, Molinoff PB, et al., editors. Goodman and Gilmans the pharmacological basis of therapeutics. 9th ed. New York (NY): McGraw-Hill, 1996: 3-29
    • (1996) Goodman and Gilmans the Pharmacological Basis of Therapeutics. 9th Ed. , pp. 3-29
    • Benet, L.Z.1    Kroetz, D.L.2    Sheiner, L.B.3
  • 20
    • 0025134337 scopus 로고
    • Cyclosporin A drug interactions: Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin a oxidase) in primary cultures of human hepatocytes and in liver microsomes
    • Pichard L, Fahre I, Fabre G, et al. Cyclosporin A drug interactions: screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes. Drug Metab Dispos 1990; 18: 595-605
    • (1990) Drug Metab Dispos , vol.18 , pp. 595-605
    • Pichard, L.1    Fahre, I.2    Fabre, G.3
  • 21
    • 0022998708 scopus 로고
    • Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation: A prototype for genetic polymorphism in oxidative drug metabolism
    • Guengerich FP, Maartin MV, Beaune PH, et al. Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation: a prototype for genetic polymorphism in oxidative drug metabolism. J Biol Chem 1986; 261: 5051-60
    • (1986) J Biol Chem , vol.261 , pp. 5051-5060
    • Guengerich, F.P.1    Maartin, M.V.2    Beaune, P.H.3
  • 22
    • 0025860978 scopus 로고
    • Oxidation of dihydropyridine calcium channel blockers and analogues by human liver cytochrome P450 IIIA4
    • Guengerieh FP, Brian WR, Iwasaki M, et al. Oxidation of dihydropyridine calcium channel blockers and analogues by human liver cytochrome P450 IIIA4. J Med Chem 1991; 34: 1838-44
    • (1991) J Med Chem , vol.34 , pp. 1838-1844
    • Guengerieh, F.P.1    Brian, W.R.2    Iwasaki, M.3
  • 23
    • 0024534194 scopus 로고
    • Isolation and characterization of human fetal liver cytochrome P450HLp2: A third member of the P450III gene family
    • Wrighton SA, Vandenbranden M. Isolation and characterization of human fetal liver cytochrome P450HLp2: a third member of the P450III gene family. Arch Biochem Biophys 1989; 268: 144-51
    • (1989) Arch Biochem Biophys , vol.268 , pp. 144-151
    • Wrighton, S.A.1    Vandenbranden, M.2
  • 24
    • 0024400702 scopus 로고
    • Identification of a polymorphically expressed member of the human cytochrome P-450III family
    • Wrighton SA, Ring BJ, Watkins PB, et al. Identification of a polymorphically expressed member of the human cytochrome P-450III family. Mol Pharmacol 1989; 86: 97-105
    • (1989) Mol Pharmacol , vol.86 , pp. 97-105
    • Wrighton, S.A.1    Ring, B.J.2    Watkins, P.B.3
  • 25
    • 0025161416 scopus 로고
    • Studies on the expression and metabolic capabilities of human liver cytochrome P450IIIA5 (HLp3)
    • Wrighton SA, Brian WR, Sari MA, et al. Studies on the expression and metabolic capabilities of human liver cytochrome P450IIIA5 (HLp3). Mol Pharmacol 1990; 38: 207-13
    • (1990) Mol Pharmacol , vol.38 , pp. 207-213
    • Wrighton, S.A.1    Brian, W.R.2    Sari, M.A.3
  • 26
    • 0025719746 scopus 로고
    • First-pass metabolism of cyclosporin by the gut
    • Kolars JC, Awni WM, Merion RM, et al. First-pass metabolism of cyclosporin by the gut. Lancet 1991; 338: 1488-90
    • (1991) Lancet , vol.338 , pp. 1488-1490
    • Kolars, J.C.1    Awni, W.M.2    Merion, R.M.3
  • 27
    • 0029978949 scopus 로고    scopus 로고
    • Influence of diet and nutritional status on drug metabolism
    • Walter-Sack I, Klotz U. Influence of diet and nutritional status on drug metabolism. Clin Pharmacokinet 1996; 31: 47-64
    • (1996) Clin Pharmacokinet , vol.31 , pp. 47-64
    • Walter-Sack, I.1    Klotz, U.2
  • 28
    • 0027155665 scopus 로고
    • Grapefruit juice-felodipine interaction: Mechanism, predictability and effect of naringin
    • Bailey DG, Arnold JMO, Munoz C, et al. Grapefruit juice-felodipine interaction: mechanism, predictability and effect of naringin. Clin Pharmacol Ther 1993; 53
    • (1993) Clin Pharmacol Ther , vol.53
    • Bailey, D.G.1    Arnold, J.M.O.2    Munoz, C.3
  • 29
    • 0026459382 scopus 로고
    • Speculations on the substrate structure-activity relationship (SSAR) of cytochrome P450 enzymes
    • Smith DA, Jones BC. Speculations on the substrate structure-activity relationship (SSAR) of cytochrome P450 enzymes. Biochem Pharmacol 1992; 44: 2089-98
    • (1992) Biochem Pharmacol , vol.44 , pp. 2089-2098
    • Smith, D.A.1    Jones, B.C.2
  • 30
    • 0027314831 scopus 로고
    • Development of a pharmacophore for inhibition of human liver cytochrome P-450 2D6: Molecular modeling and inhibition studies
    • Strobl GR, von Kruedener S, Stöckigt J, et al. Development of a pharmacophore for inhibition of human liver cytochrome P-450 2D6: molecular modeling and inhibition studies. J Med Chem 1993; 36: 1136-45
    • (1993) J Med Chem , vol.36 , pp. 1136-1145
    • Strobl, G.R.1    Von Kruedener, S.2    Stöckigt, J.3
  • 31
    • 0024796958 scopus 로고
    • The human debrisoquine 4-hydroxylation (CYP2D) locus: Sequence and identification of the polymorphic CYP2D6 gene, a related gene and pseudogene
    • Kimura S, Umeno M, Skoda RC, et al. The human debrisoquine 4-hydroxylation (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene and pseudogene. Am J Hum Genet 1989; 45: 889-90
    • (1989) Am J Hum Genet , vol.45 , pp. 889-890
    • Kimura, S.1    Umeno, M.2    Skoda, R.C.3
  • 32
    • 0025305464 scopus 로고
    • The genetic polymorphism of debrisoquin/sparteine metabolism-clinical aspects
    • Eichelbaum M, Gross AS. The genetic polymorphism of debrisoquin/sparteine metabolism-clinical aspects. Pharmacol Ther 1990; 46: 377-94
    • (1990) Pharmacol Ther , vol.46 , pp. 377-394
    • Eichelbaum, M.1    Gross, A.S.2
  • 33
    • 0025940815 scopus 로고
    • Molecular genetics of the debrisoquin/sparteine polymorphism
    • Gonzalez FJ, Meyer UA. Molecular genetics of the debrisoquin/sparteine polymorphism. Clin Pharmacol Ther 1991; 50; 233-8
    • (1991) Clin Pharmacol Ther , vol.50 , pp. 233-238
    • Gonzalez, F.J.1    Meyer, U.A.2
  • 34
    • 0027136288 scopus 로고
    • Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of derisoquine
    • Johansson I, Lundqvist E, Bertilsson L. Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of derisoquine. Proc Natl Acad Sci 1993; 90: 11825-9
    • (1993) Proc Natl Acad Sci , vol.90 , pp. 11825-11829
    • Johansson, I.1    Lundqvist, E.2    Bertilsson, L.3
  • 35
    • 0028942981 scopus 로고
    • Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population
    • Agúndez JA, Ledesma MC, Ladero JM, et al. Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population. Clin Pharmacol Ther 1995; 57: 265-9
    • (1995) Clin Pharmacol Ther , vol.57 , pp. 265-269
    • Agúndez, J.A.1    Ledesma, M.C.2    Ladero, J.M.3
  • 36
    • 0026670643 scopus 로고
    • Prediction of phenotype for acetylation and for debrisoquin hydroxylation by DNA tests in healthy human volunteers
    • Graf T, Broly F, Hoffmann F. Prediction of phenotype for acetylation and for debrisoquin hydroxylation by DNA tests in healthy human volunteers. Eur J Clin Pharmacol 1992; 43: 399-403
    • (1992) Eur J Clin Pharmacol , vol.43 , pp. 399-403
    • Graf, T.1    Broly, F.2    Hoffmann, F.3
  • 37
    • 0026610576 scopus 로고
    • Analysis of the CYP2D6 gene in relation to debrisoquin and desipramine hydroxylation in a swedish population
    • Dahl M-J, Johansson I, Palmertz MP, et al. Analysis of the CYP2D6 gene in relation to debrisoquin and desipramine hydroxylation in a swedish population. Clin Pharmacol Ther 1992; 51: 12-7
    • (1992) Clin Pharmacol Ther , vol.51 , pp. 12-17
    • Dahl, M.-J.1    Johansson, I.2    Palmertz, M.P.3
  • 38
    • 0025950370 scopus 로고
    • Debrisoquin/sparteine hydroxylation genotype and phenotype: Analysis of common mutations and alleles of CYP2D6 in a European population
    • Broly F, Gaedigk A, Heim M, et al. Debrisoquin/sparteine hydroxylation genotype and phenotype: analysis of common mutations and alleles of CYP2D6 in a European population. DNA Cell Biol 1991; 10: 545-58
    • (1991) DNA Cell Biol , vol.10 , pp. 545-558
    • Broly, F.1    Gaedigk, A.2    Heim, M.3
  • 39
    • 0026506140 scopus 로고
    • Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin
    • Bertilsson L, Lou Y-Q, Du Y-L, et al. Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin. Clin Pharmacol Ther 1992; 51: 388-97
    • (1992) Clin Pharmacol Ther , vol.51 , pp. 388-397
    • Bertilsson, L.1    Lou, Y.-Q.2    Du, Y.-L.3
  • 40
    • 0028997955 scopus 로고
    • 'Its the genes stupid': Molecular basis and clinical consequences of genetic cytochrome P450 2D6 polymorphism
    • Kroemer HK, Eichelbaum M. 'Its the genes stupid': molecular basis and clinical consequences of genetic cytochrome P450 2D6 polymorphism. Life Sci 1995; 56: 2285-98
    • (1995) Life Sci , vol.56 , pp. 2285-2298
    • Kroemer, H.K.1    Eichelbaum, M.2
  • 41
    • 0029075613 scopus 로고
    • Interindividual variations of desmethylation and hydroxylation of amitriptyline in a Japanese psychiatric population
    • Shimoda K, Noguchi T, Morita S, et al. Interindividual variations of desmethylation and hydroxylation of amitriptyline in a Japanese psychiatric population. J Clin Psychopharmacol 1995; 15: 175-81
    • (1995) J Clin Psychopharmacol , vol.15 , pp. 175-181
    • Shimoda, K.1    Noguchi, T.2    Morita, S.3
  • 42
    • 0029558898 scopus 로고
    • N-demethylation of amitriptyline in vitro: Role of cytochrome P-450 3A (CYP3A) isoforms and effect of metabolic inhibitors
    • Schmider J, Greenblatt DJ, Von Moltke L, et al. N-demethylation of amitriptyline in vitro: role of cytochrome P-450 3A (CYP3A) isoforms and effect of metabolic inhibitors. J Pharmacol Exp Ther 1995; 275: 592-7
    • (1995) J Pharmacol Exp Ther , vol.275 , pp. 592-597
    • Schmider, J.1    Greenblatt, D.J.2    Von Moltke, L.3
  • 43
    • 0027456438 scopus 로고
    • Inhibition by fluoxetine of cytochrome P450 2D6 activity
    • Otton SV, Wu D, Joffe RT, et al. Inhibition by fluoxetine of cytochrome P450 2D6 activity. Clin Pharmacol Ther 1993; 53: 401-9
    • (1993) Clin Pharmacol Ther , vol.53 , pp. 401-409
    • Otton, S.V.1    Wu, D.2    Joffe, R.T.3
  • 44
    • 0027167470 scopus 로고
    • Inhibition by paroxetine of desipramine metabolism in extensive but not in poor metabolizers of sparteine
    • Brosen K, Hansen JG, Nielsen KK, et al. Inhibition by paroxetine of desipramine metabolism in extensive but not in poor metabolizers of sparteine. Eur J Clin Pharmacol 1993; 1993: 349-55
    • (1993) Eur J Clin Pharmacol , vol.1993 , pp. 349-355
    • Brosen, K.1    Hansen, J.G.2    Nielsen, K.K.3
  • 45
    • 0028194864 scopus 로고
    • Inhibition of desipramine hydroxylation in vitro by serotonin-reuptake-inhihitor antidepressants, and by quinidine and ketoconazole: A model system to predict drug interactions in vivo
    • von Moltke LL, Greenblatt DJ, Cotreau-Bibbo MM, et al. Inhibition of desipramine hydroxylation in vitro by serotonin-reuptake-inhihitor antidepressants, and by quinidine and ketoconazole: a model system to predict drug interactions in vivo. J Pharmacol Exp Ther 1994; 268: 1278-83
    • (1994) J Pharmacol Exp Ther , vol.268 , pp. 1278-1283
    • Von Moltke, L.L.1    Greenblatt, D.J.2    Cotreau-Bibbo, M.M.3
  • 46
    • 0026519541 scopus 로고
    • Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: A role for P-450-2C9 in the etiology of (S)-warfarin-drug interactions
    • Rettie AE, Korzewaka KR, Kunze KL, et al. Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-450-2C9 in the etiology of (S)-warfarin-drug interactions. Chem Res Toxicol 1992; 5: 54-9
    • (1992) Chem Res Toxicol , vol.5 , pp. 54-59
    • Rettie, A.E.1    Korzewaka, K.R.2    Kunze, K.L.3
  • 47
    • 0025299490 scopus 로고
    • Slow omeprazole metabolizers are also poor S-mephenytoin hydroxylators
    • Andersson T, Regardh CG, Dahl-Puustinen ML, et al. Slow omeprazole metabolizers are also poor S-mephenytoin hydroxylators. Ther Drug Monitor 1990; 12: 415-6
    • (1990) Ther Drug Monitor , vol.12 , pp. 415-416
    • Andersson, T.1    Regardh, C.G.2    Dahl-Puustinen, M.L.3
  • 48
    • 0026816971 scopus 로고
    • Polymorphic hydroxylation of S-mephenytoin and omeprazole metabolism in Caucasian and Chinese subjects
    • Andersson T, Regardh CG, Lou YC, et al. Polymorphic hydroxylation of S-mephenytoin and omeprazole metabolism in Caucasian and Chinese subjects. Pharmacogenetics 1992; 2: 25-31
    • (1992) Pharmacogenetics , vol.2 , pp. 25-31
    • Andersson, T.1    Regardh, C.G.2    Lou, Y.C.3
  • 49
    • 0028260641 scopus 로고
    • A major genetic defect responsible for the polymorphism of S-mephentoin metabolism in humans
    • DeMorais SMF, Wilkinson GR, Blaisdell J, et al. A major genetic defect responsible for the polymorphism of S-mephentoin metabolism in humans. J Biol Chem 1994; 269: 15419-22
    • (1994) J Biol Chem , vol.269 , pp. 15419-15422
    • DeMorais, S.M.F.1    Wilkinson, G.R.2    Blaisdell, J.3
  • 50
    • 0029127629 scopus 로고
    • Interethnic difference in omeprazoles inhibition of diazepam metabolism
    • Caraco Y, Tateishi T, Wood AJJ. Interethnic difference in omeprazoles inhibition of diazepam metabolism. Clin Pharmacol Ther 1995; 58: 62-72
    • (1995) Clin Pharmacol Ther , vol.58 , pp. 62-72
    • Caraco, Y.1    Tateishi, T.2    Wood, A.J.J.3
  • 51
    • 0025064349 scopus 로고
    • Effect of omeprazole treatment on diazepam plasma levels in slow versus normal rapid metabolizers of omeprazole
    • Andersson T, Cederberg C, Edvardsson G, et al. Effect of omeprazole treatment on diazepam plasma levels in slow versus normal rapid metabolizers of omeprazole. Clin Pharmacol Ther 1990; 47: 79-85
    • (1990) Clin Pharmacol Ther , vol.47 , pp. 79-85
    • Andersson, T.1    Cederberg, C.2    Edvardsson, G.3
  • 52
    • 0025326803 scopus 로고
    • Effect of omeprazole and cimetidine on plasma diazepam levels
    • Andersson T, Andren K, Cederberg C, et al. Effect of omeprazole and cimetidine on plasma diazepam levels. Eur J Clin Pharmacol 1990; 39: 51-4
    • (1990) Eur J Clin Pharmacol , vol.39 , pp. 51-54
    • Andersson, T.1    Andren, K.2    Cederberg, C.3
  • 53
    • 0022398138 scopus 로고
    • Omeprazole inhibits oxidative drug metabolism: Studies with diazepam and phenytoin in vivo and 7-ethoxycoumarin in vitro
    • Gugler R, Jensen JC. Omeprazole inhibits oxidative drug metabolism: studies with diazepam and phenytoin in vivo and 7-ethoxycoumarin in vitro. Gastroenterology 1985; 89: 1235-41
    • (1985) Gastroenterology , vol.89 , pp. 1235-1241
    • Gugler, R.1    Jensen, J.C.2
  • 54
    • 0028860852 scopus 로고
    • Competitive inhibition of coumarin 7-hydroxylation by pilocarpine and its interaction with mouse CYP2A5 and human CYP2A6
    • Kinonen T, Pasanen M, Gynther J, et al. Competitive inhibition of coumarin 7-hydroxylation by pilocarpine and its interaction with mouse CYP2A5 and human CYP2A6. Br J Pharmacol 1995; 116: 2625-30
    • (1995) Br J Pharmacol , vol.116 , pp. 2625-2630
    • Kinonen, T.1    Pasanen, M.2    Gynther, J.3
  • 55
    • 0028586852 scopus 로고
    • Interactions of ingested food, beverage, and tobacco components involving human cytochrome P4501A2, 2A6, 2E1, and 3A4 enzymes
    • Guengerich FP, Shimada T, Yun C-H, et al. Interactions of ingested food, beverage, and tobacco components involving human cytochrome P4501A2, 2A6, 2E1, and 3A4 enzymes. Environ Health Perspect 1994; 102: 49-53
    • (1994) Environ Health Perspect , vol.102 , pp. 49-53
    • Guengerich, F.P.1    Shimada, T.2    Yun, C.-H.3
  • 57
    • 0021214044 scopus 로고
    • Theophylline metabolism in relation to antipyrine, debrisoquin, and sparteine metabolism
    • Dahlqvist R, Bertilsson L, Birkett DJ, et al. Theophylline metabolism in relation to antipyrine, debrisoquin, and sparteine metabolism. Clin Pharmacol Ther 1984; 35: 815-21
    • (1984) Clin Pharmacol Ther , vol.35 , pp. 815-821
    • Dahlqvist, R.1    Bertilsson, L.2    Birkett, D.J.3
  • 58
    • 0027304762 scopus 로고
    • Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics
    • Patten C, Thomas PE, Guy R, et al. Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics. Chem Res Toxicol 1993; 6: 511-8
    • (1993) Chem Res Toxicol , vol.6 , pp. 511-518
    • Patten, C.1    Thomas, P.E.2    Guy, R.3
  • 59
    • 85036449301 scopus 로고    scopus 로고
    • Characterization of tacrine metabolism and bioactivation using heterologous expression systems and inhibition studies: Evidence for CYP1A2 involvement
    • abstract no. 139. 1993 Oct 17-20; Tucson, Arizona. Bethesda (MD): International Society for the Study of Xenobiotics (ISSX)
    • Woolf TF, Pool WF, Kukan M, et al. Characterization of tacrine metabolism and bioactivation using heterologous expression systems and inhibition studies: evidence for CYP1A2 involvement [abstract no. 139]. 5th North American International Society for the Study of Xenobiotics Meeting; 1993 Oct 17-20; Tucson, Arizona. Bethesda (MD): International Society for the Study of Xenobiotics (ISSX) 4: 17-21
    • 5th North American International Society for the Study of Xenobiotics Meeting , vol.4 , pp. 17-21
    • Woolf, T.F.1    Pool, W.F.2    Kukan, M.3
  • 60
    • 0027985726 scopus 로고
    • Clozapine disposition covaries with CYP1A2 activity determined by a caffeine test
    • Bertilsson L, Carrillo JA, Dahl M-L, et al. Clozapine disposition covaries with CYP1A2 activity determined by a caffeine test. Br J Clin Pharmacol 1994; 38: 471-3
    • (1994) Br J Clin Pharmacol , vol.38 , pp. 471-473
    • Bertilsson, L.1    Carrillo, J.A.2    Dahl, M.-L.3
  • 61
    • 0026849441 scopus 로고
    • Biotransformation of caffeine, paraxanthine, theobromine and theophylline by c-DNA expressed human CYP1A2 and CYP1E1
    • Gu L, Gonzalez PJ, Kalow W, et al. Biotransformation of caffeine, paraxanthine, theobromine and theophylline by c-DNA expressed human CYP1A2 and CYP1E1. Pharmacogenetics 1992; 2: 73-7
    • (1992) Pharmacogenetics , vol.2 , pp. 73-77
    • Gu, L.1    Gonzalez, P.J.2    Kalow, W.3
  • 62
    • 0029125983 scopus 로고
    • Fluvoxamine: A review of global drug-drug interaction data
    • Wagner W, Vause EW. Fluvoxamine: a review of global drug-drug interaction data. Clin Pharmacokinet 1995; 29: 26-32
    • (1995) Clin Pharmacokinet , vol.29 , pp. 26-32
    • Wagner, W.1    Vause, E.W.2
  • 63
    • 0026567713 scopus 로고
    • Oxidative and reductive metabolism by cytochrome P450 2E1
    • Koop DR. Oxidative and reductive metabolism by cytochrome P450 2E1. FASEB J 1992; 6: 724-30
    • (1992) FASEB J , vol.6 , pp. 724-730
    • Koop, D.R.1
  • 64
    • 0025223625 scopus 로고
    • Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450 IIE1
    • Böcker PR, Beaune PH, Iwasaki M, et al. Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450 IIE1. Chem Res Toxicol 1990; 3: 566-73
    • (1990) Chem Res Toxicol , vol.3 , pp. 566-573
    • Böcker, P.R.1    Beaune, P.H.2    Iwasaki, M.3
  • 66
    • 0029146538 scopus 로고
    • Antidepressant drug interactions and the cytochrome P450 system: The role of cytochrome P450 2D6
    • Ereshefsky L, Riesenman C, Lam YWF. Antidepressant drug interactions and the cytochrome P450 system: the role of cytochrome P450 2D6. Clin Pharmacokinet 1995; 29: 10-9
    • (1995) Clin Pharmacokinet , vol.29 , pp. 10-19
    • Ereshefsky, L.1    Riesenman, C.2    Lam, Y.W.F.3
  • 67
    • 0029125984 scopus 로고
    • Metabolism of drugs by cytochrome P450 3A isoforms: Implications for drug interactions in psychopharmacology
    • von Moltke LL, Greenblatt D, Schmider J, et al. Metabolism of drugs by cytochrome P450 3A isoforms: implications for drug interactions in psychopharmacology. Clin Pharmacokinet 1995; 29: 33-44
    • (1995) Clin Pharmacokinet , vol.29 , pp. 33-44
    • Von Moltke, L.L.1    Greenblatt, D.2    Schmider, J.3
  • 68
    • 0002618678 scopus 로고
    • Quantitative predictions of in vivo drug metabolism and interactions from in vitro data
    • Pacifici GM, Fracchia GN, editors. Brussels: European Commision
    • Leeman TD, Dayer P. Quantitative predictions of in vivo drug metabolism and interactions from in vitro data. In: Pacifici GM, Fracchia GN, editors. Advances in drug metabolism. Brussels: European Commision, 1995: 785-830
    • (1995) Advances in Drug Metabolism , pp. 785-830
    • Leeman, T.D.1    Dayer, P.2
  • 69
    • 0023132476 scopus 로고
    • Clearance approaches in pharmacology
    • Wilkinson GR. Clearance approaches in pharmacology. Pharmacol Rev 1987; 39: 1-47
    • (1987) Pharmacol Rev , vol.39 , pp. 1-47
    • Wilkinson, G.R.1
  • 70
    • 0024993409 scopus 로고
    • Phosphatidylserine as a determinant for the tissue distribution of weakly basic drugs
    • Yata N, Toyoda T, Murakami T, et al. Phosphatidylserine as a determinant for the tissue distribution of weakly basic drugs. Pharm Res 1990; 10: 1019-25
    • (1990) Pharm Res , vol.10 , pp. 1019-1025
    • Yata, N.1    Toyoda, T.2    Murakami, T.3
  • 71
    • 0028987970 scopus 로고
    • The effects of cytochrome b5, NADPH-450 reductase and lipid on the rate of 6β-hydroxylation of testosterone as catalyzed by human P450 3A4 fusion protein
    • Shet MS, Faulkner KM, Holmans PL, et al. The effects of cytochrome b5, NADPH-450 reductase and lipid on the rate of 6β-hydroxylation of testosterone as catalyzed by human P450 3A4 fusion protein. Arch Biochem Biophys 1995; 318: 314-21
    • (1995) Arch Biochem Biophys , vol.318 , pp. 314-321
    • Shet, M.S.1    Faulkner, K.M.2    Holmans, P.L.3
  • 72
    • 0028054999 scopus 로고
    • Extrahepatic metabolism of drugs in humans
    • Krishna DR, Klotz U. Extrahepatic metabolism of drugs in humans. Clin Pharmacokinet 1994; 26: 144-60
    • (1994) Clin Pharmacokinet , vol.26 , pp. 144-160
    • Krishna, D.R.1    Klotz, U.2
  • 73
    • 0029123393 scopus 로고
    • The effects of ketoconazole on the intestinal metabolism and bioavailability of cyclosporine
    • Gomez DY, Wacher VJ, Tomlanovich SJ, et al. The effects of ketoconazole on the intestinal metabolism and bioavailability of cyclosporine. Clin Pharmacol Ther 1995; 58: 15-9
    • (1995) Clin Pharmacol Ther , vol.58 , pp. 15-19
    • Gomez, D.Y.1    Wacher, V.J.2    Tomlanovich, S.J.3
  • 74
    • 0026457407 scopus 로고
    • Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction
    • Herbert MF, Roberts JP, Prueksaritanont T, et al. Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction. Clin Pharmacol Ther 1992; 52: 453-7
    • (1992) Clin Pharmacol Ther , vol.52 , pp. 453-457
    • Herbert, M.F.1    Roberts, J.P.2    Prueksaritanont, T.3
  • 75
    • 0029028792 scopus 로고
    • Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: Implications for drug delivery and activity in cancer chemotherapy
    • Wacher VJ, Wu C-Y, Benet LZ. Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: Implications for drug delivery and activity in cancer chemotherapy. Mol Carcinog 1995; 13: 129-34
    • (1995) Mol Carcinog , vol.13 , pp. 129-134
    • Wacher, V.J.1    Wu, C.-Y.2    Benet, L.Z.3
  • 76
    • 0025367770 scopus 로고
    • Multidrug resistance genes, P-glycoprotein and the liver
    • Arias IM. Multidrug resistance genes, P-glycoprotein and the liver. Hepatology 1990; 12: 159-65
    • (1990) Hepatology , vol.12 , pp. 159-165
    • Arias, I.M.1
  • 77
    • 0344222368 scopus 로고    scopus 로고
    • Assessment of multiple doses of ritonavir on the pharmacokinetics of rifabutin
    • abstract Mo.B.1199. Jul 7-12: Vancouver
    • Cato A, Cavanaugh JH, Shi H, et al. Assessment of multiple doses of ritonavir on the pharmacokinetics of rifabutin [abstract Mo.B.1199]. XI International Conference on AIDS; 1996 Jul 7-12: Vancouver
    • (1996) XI International Conference on AIDS
    • Cato, A.1    Cavanaugh, J.H.2    Shi, H.3
  • 78
    • 0343001334 scopus 로고    scopus 로고
    • Assessment of the pharmacokinetic interaction between ritonavir and clarithromycin
    • Ouellet D, Hsu A, Granneman GR, et al. Assessment of the pharmacokinetic interaction between ritonavir and clarithromycin. Clin Pharmacol Ther 1996; 59: 143
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 143
    • Ouellet, D.1    Hsu, A.2    Granneman, G.R.3
  • 79
    • 0025055648 scopus 로고
    • Enzyme induction in the cytochrome P-450 system
    • Okey AB. Enzyme induction in the cytochrome P-450 system. Pharmacol Ther 1990; 45: 241-98
    • (1990) Pharmacol Ther , vol.45 , pp. 241-298
    • Okey, A.B.1
  • 80
    • 0025035723 scopus 로고
    • Enzyme induction and inhibition
    • Barry M, Feely J. Enzyme induction and inhibition. Pharmacol Ther 1990; 48: 71-94
    • (1990) Pharmacol Ther , vol.48 , pp. 71-94
    • Barry, M.1    Feely, J.2
  • 81
    • 8044243063 scopus 로고
    • Enzyme induction, lipids, and apolipoproteins
    • Sotaniemi EA, Pelkonen RO, editors. Bristol (PA): Taylor & Francis
    • Luoma PV. Enzyme induction, lipids, and apolipoproteins. In: Sotaniemi EA, Pelkonen RO, editors. Enzyme induction in man. Bristol (PA): Taylor & Francis, 1987: 231-42
    • (1987) Enzyme Induction in Man , pp. 231-242
    • Luoma, P.V.1
  • 82
    • 0009872253 scopus 로고    scopus 로고
    • Assessment of multiple doses of ritonavir on the pharmacokinetics of theophylline
    • Abstract Mo.B. 1200. Jul 7-12; Vancouver
    • Hsu A, Granneman GR, Witt G, et al. Assessment of multiple doses of ritonavir on the pharmacokinetics of theophylline [Abstract Mo.B. 1200]. XI International Conference on AIDS; 1996 Jul 7-12; Vancouver
    • (1996) XI International Conference on AIDS
    • Hsu, A.1    Granneman, G.R.2    Witt, G.3
  • 83
    • 1842275677 scopus 로고    scopus 로고
    • Effect of ritonavir on the pharmacokinetics of ethinyl estradiol in healthy female volunteers
    • Abstract Mo.B. 1198. Jul 7-12; Vancouver
    • Ouellet D, Hsu A, Qian J, et al. Effect of ritonavir on the pharmacokinetics of ethinyl estradiol in healthy female volunteers [Abstract Mo.B. 1198]. XI International Conference on AIDS; 1996 Jul 7-12; Vancouver
    • (1996) XI International Conference on AIDS
    • Ouellet, D.1    Hsu, A.2    Qian, J.3
  • 84
    • 7344246618 scopus 로고
    • Assessment of the pharmacokinetic interaction between the HIV-1 protease inhibitor ABT-538 and zidovudine
    • Abstract 134. Sept 17-20; San Francisco
    • Cato III A, Hsu A, Granneman R, et al. Assessment of the pharmacokinetic interaction between the HIV-1 protease inhibitor ABT-538 and zidovudine [Abstract 134]. 35th ICAAC Annual Meeting 1995; 1995 Sept 17-20; San Francisco
    • (1995) 35th ICAAC Annual Meeting 1995
    • Cato III, A.1    Hsu, A.2    Granneman, R.3
  • 85
    • 0027973024 scopus 로고
    • Theophylline N-demethylations as probes for P450 1A1 and P450 1A2
    • Sarker MA, Jackson BJ. Theophylline N-demethylations as probes for P450 1A1 and P450 1A2. Drug Metab Dispos 1994; 22: 827-34
    • (1994) Drug Metab Dispos , vol.22 , pp. 827-834
    • Sarker, M.A.1    Jackson, B.J.2
  • 86
    • 0019785149 scopus 로고
    • The effects of erythromycin on the absorption and disposition kinetics of theophylline
    • Branigan TA, Robins RA, Cady WJ, et al. The effects of erythromycin on the absorption and disposition kinetics of theophylline. Eur J Clin Pharmacol 1981; 21: 115-20
    • (1981) Eur J Clin Pharmacol , vol.21 , pp. 115-120
    • Branigan, T.A.1    Robins, R.A.2    Cady, W.J.3
  • 87
    • 0017340974 scopus 로고
    • Inhibition of theophylline clearance by troleandomycin
    • Weinberger M, Hudgel D, Spector S, et al. Inhibition of theophylline clearance by troleandomycin. J Allergy Clin Immunol 1977; 59: 228-31
    • (1977) J Allergy Clin Immunol , vol.59 , pp. 228-231
    • Weinberger, M.1    Hudgel, D.2    Spector, S.3
  • 88
    • 0024399217 scopus 로고
    • The effect of the of administration of the cimetidine-theophylline drug interaction
    • Cramer KF, Secor J, Speeg KV. The effect of the of administration of the cimetidine-theophylline drug interaction. J Clin Pharmacol 1989; 29: 451-6
    • (1989) J Clin Pharmacol , vol.29 , pp. 451-456
    • Cramer, K.F.1    Secor, J.2    Speeg, K.V.3
  • 89
    • 0026583361 scopus 로고
    • Effects of 2 quinolone antibacterials, temafloxin andenoxacin on theophylline pharmacokinetics
    • Sörgel F, Mahr G, Granneman GR, et al. Effects of 2 quinolone antibacterials, temafloxin andenoxacin on theophylline pharmacokinetics. Clin Pharmacokinet 1992; 22: 65-74
    • (1992) Clin Pharmacokinet , vol.22 , pp. 65-74
    • Sörgel, F.1    Mahr, G.2    Granneman, G.R.3
  • 91
    • 0028357256 scopus 로고
    • Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole and itraconazole
    • Olkkola KT, Backman JT, Neuvonen PJ. Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole and itraconazole. Clin Pharmacol Ther 1994; 55: 481-5
    • (1994) Clin Pharmacol Ther , vol.55 , pp. 481-485
    • Olkkola, K.T.1    Backman, J.T.2    Neuvonen, P.J.3
  • 92
    • 0025374791 scopus 로고
    • Quinidine reduces clearance of (+)-propranolol more than (-)-propranolol through marked reduction in 4-hydroxylation
    • Zhou H-H, Anthony LB, Roden DM, et al. Quinidine reduces clearance of (+)-propranolol more than (-)-propranolol through marked reduction in 4-hydroxylation. Clin Pharmacol Ther 1990; 47: 686-93
    • (1990) Clin Pharmacol Ther , vol.47 , pp. 686-693
    • Zhou, H.-H.1    Anthony, L.B.2    Roden, D.M.3
  • 93
    • 0029926747 scopus 로고    scopus 로고
    • Quinidine inhibits the 7-hydroxylation of chlorpromazine in extensive metabolizers
    • Muralidharan G, Cooper JK, Hawes EM, et al. Quinidine inhibits the 7-hydroxylation of chlorpromazine in extensive metabolizers. Eur J Clin Pharmacol 1996; 50: 121-8
    • (1996) Eur J Clin Pharmacol , vol.50 , pp. 121-128
    • Muralidharan, G.1    Cooper, J.K.2    Hawes, E.M.3
  • 94
    • 0026808682 scopus 로고
    • Identification of the pharmacogenetic determinants of alfentanil metabolism: Cytochrome P-450 3A4. An explanation of the variable elimination clearance
    • Yun CH, Wood M, Wood AJ, et al. Identification of the pharmacogenetic determinants of alfentanil metabolism: cytochrome P-450 3A4. An explanation of the variable elimination clearance. Anesthesiology 1992; 77: 467-74
    • (1992) Anesthesiology , vol.77 , pp. 467-474
    • Yun, C.H.1    Wood, M.2    Wood, A.J.3
  • 95
    • 0028933307 scopus 로고
    • Catalytic role of cytochrome P4503A4 in multiple pathways of alfentanil metabolism
    • Labroo RB, Thummel KE, Kunze KL, et al. Catalytic role of cytochrome P4503A4 in multiple pathways of alfentanil metabolism. Drug Metab Dispos 1995; 23: 490-6
    • (1995) Drug Metab Dispos , vol.23 , pp. 490-496
    • Labroo, R.B.1    Thummel, K.E.2    Kunze, K.L.3
  • 96
    • 0029022306 scopus 로고
    • Clinical pharmacokinetics and pharmacodynamics of opioid analgesics in infants and children
    • Olkkola KT, Hamunen K, Maunuksela E-L. Clinical pharmacokinetics and pharmacodynamics of opioid analgesics in infants and children. Clin Pharmacokinet 1995; 28: 385-404
    • (1995) Clin Pharmacokinet , vol.28 , pp. 385-404
    • Olkkola, K.T.1    Hamunen, K.2    Maunuksela, E.-L.3
  • 97
    • 0028102911 scopus 로고
    • The influence of pharmacogenetics on opoid analgesia: Studies with codeine and oxycodone in the Sprague-Dawley/Dark Agouti rat model
    • Cleary J, Mikus G, Somogyi A, et al. The influence of pharmacogenetics on opoid analgesia: Studies with codeine and oxycodone in the Sprague-Dawley/Dark Agouti rat model. J Pharmacol Exp Ther 1994; 271: 1528-34
    • (1994) J Pharmacol Exp Ther , vol.271 , pp. 1528-1534
    • Cleary, J.1    Mikus, G.2    Somogyi, A.3
  • 98
    • 0029003283 scopus 로고
    • Codeine metabolism in three Oriental populations: A pilot study in Chinese, Japanese and Koreans
    • Yue Q-Y, Svennson J-O, Säwe J, et al. Codeine metabolism in three Oriental populations: a pilot study in Chinese, Japanese and Koreans. Pharmacogenetics 1995; 5: 173-7
    • (1995) Pharmacogenetics , vol.5 , pp. 173-177
    • Yue, Q.-Y.1    Svennson, J.-O.2    Säwe, J.3
  • 99
    • 0029622428 scopus 로고
    • The pharmacogenetics of codeine hypoalgesia
    • Sindrup SH, Brosen K. The pharmacogenetics of codeine hypoalgesia. Pharmacogenetics 1995; 5: 335-46
    • (1995) Pharmacogenetics , vol.5 , pp. 335-346
    • Sindrup, S.H.1    Brosen, K.2
  • 100
    • 0029981345 scopus 로고    scopus 로고
    • Impact of quinidine on plasma and cerebrospinal fluid concentrations of codeine and morphine after codeine intake
    • Sindrup SH, Hofmann U, Asmussen J, et al. Impact of quinidine on plasma and cerebrospinal fluid concentrations of codeine and morphine after codeine intake. Eur J Clin Pharmacol 1996; 49: 503-9
    • (1996) Eur J Clin Pharmacol , vol.49 , pp. 503-509
    • Sindrup, S.H.1    Hofmann, U.2    Asmussen, J.3
  • 101
    • 0029680208 scopus 로고    scopus 로고
    • Microsomal codeine N-demethylation: Cosegregation with cytochrome P4503A4 activity
    • Caraco Y, Tateishi T, Guengerich FP, et al. Microsomal codeine N-demethylation: cosegregation with cytochrome P4503A4 activity. Drug Metab Dispos 1996; 24: 761-4
    • (1996) Drug Metab Dispos , vol.24 , pp. 761-764
    • Caraco, Y.1    Tateishi, T.2    Guengerich, F.P.3
  • 102
    • 0029620771 scopus 로고
    • Biotransformation of tritiated fentanyl in human liver microsomes. Monitoring metabolism using phenylacetic acid and 2-phenylethanol
    • Tateishi T, Wood AJJ, Guengerich FP, et al. Biotransformation of tritiated fentanyl in human liver microsomes. Monitoring metabolism using phenylacetic acid and 2-phenylethanol. Biochem Pharmacol 1995; 50: 1921-4
    • (1995) Biochem Pharmacol , vol.50 , pp. 1921-1924
    • Tateishi, T.1    Wood, A.J.J.2    Guengerich, F.P.3
  • 103
    • 0030041685 scopus 로고    scopus 로고
    • Identification of human liver cytochrome P-450 3A4 as the enzyme responsible for fentanyl and sufentanil n-dealkylation
    • Tateishi T, Krivoruk Y, Ueng Y-F, et al. Identification of human liver cytochrome P-450 3A4 as the enzyme responsible for fentanyl and sufentanil n-dealkylation. Anesth Analg 1996; 82: 167-72
    • (1996) Anesth Analg , vol.82 , pp. 167-172
    • Tateishi, T.1    Krivoruk, Y.2    Ueng, Y.-F.3
  • 104
    • 0028035064 scopus 로고
    • Determination of 6-monoacetylmorphine and morphine in plasma, whole blood and urine using high-performance liquid chromatography with electrochemical detection
    • Rop PP, Grimaldi F, Burle J, et al. Determination of 6-monoacetylmorphine and morphine in plasma, whole blood and urine using high-performance liquid chromatography with electrochemical detection. J Chromatogr B Biomed Appl 1994; 661: 245-53
    • (1994) J Chromatogr B Biomed Appl , vol.661 , pp. 245-253
    • Rop, P.P.1    Grimaldi, F.2    Burle, J.3
  • 105
    • 0021321402 scopus 로고
    • The pharmacokinetics of heroin in patients with chronic pain
    • Inturrisi CE, Max MB, Foley KM. The pharmacokinetics of heroin in patients with chronic pain. N Engl J Med 1984; 310: 1213-7
    • (1984) N Engl J Med , vol.310 , pp. 1213-1217
    • Inturrisi, C.E.1    Max, M.B.2    Foley, K.M.3
  • 106
    • 0027381603 scopus 로고
    • CYP2D6 phenotype determines the metabolic conversion of hydrocodone to hydromorphone
    • Otton SV, Schadel M, Cheung SW, et al. CYP2D6 phenotype determines the metabolic conversion of hydrocodone to hydromorphone. Clin Pharmacol Ther 1995; 54: 463-72
    • (1995) Clin Pharmacol Ther , vol.54 , pp. 463-472
    • Otton, S.V.1    Schadel, M.2    Cheung, S.W.3
  • 107
    • 0028843621 scopus 로고
    • Steady-state pharmacokinetics of hydromorphone and hydromorphone-3-glucuronide in cancer patients after immediate controlled-release hydromorphone
    • Hagen N, Thirwell MP, Dhaliwal HS, et al. Steady-state pharmacokinetics of hydromorphone and hydromorphone-3-glucuronide in cancer patients after immediate controlled-release hydromorphone. J Clin Pharmacol 1995; 35: 37-44
    • (1995) J Clin Pharmacol , vol.35 , pp. 37-44
    • Hagen, N.1    Thirwell, M.P.2    Dhaliwal, H.S.3
  • 108
    • 0022003852 scopus 로고
    • Effect of phenobarbital pretreatment on the plasma and urinary levels of (-)-alpha-acetylmethadol and its metabolites
    • Kuttab SH, Nowshad F, Shargel L. Effect of phenobarbital pretreatment on the plasma and urinary levels of (-)-alpha-acetylmethadol and its metabolites. J Pharm Sci 1985; 74: 331-44
    • (1985) J Pharm Sci , vol.74 , pp. 331-344
    • Kuttab, S.H.1    Nowshad, F.2    Shargel, L.3
  • 109
    • 0026489442 scopus 로고
    • Pethidine pharmacokinetics after intramuscular dose: A comparison in Caucasian, Chinese and Nepalese patients
    • Houghton IT, Chan K, Wong YC, et al. Pethidine pharmacokinetics after intramuscular dose: a comparison in Caucasian, Chinese and Nepalese patients. Methods Find Exp Clin Pharmacol 1992; 14: 451-8
    • (1992) Methods Find Exp Clin Pharmacol , vol.14 , pp. 451-458
    • Houghton, I.T.1    Chan, K.2    Wong, Y.C.3
  • 110
  • 111
    • 0019404314 scopus 로고
    • Presystemic metabolism of meperidine to normeperidine in normal cirrhotic subjects
    • Pond SM, Tong T, Benowitz NL, et al. Presystemic metabolism of meperidine to normeperidine in normal cirrhotic subjects. Clin Pharmacol Ther 1981; 30: 183-8
    • (1981) Clin Pharmacol Ther , vol.30 , pp. 183-188
    • Pond, S.M.1    Tong, T.2    Benowitz, N.L.3
  • 112
    • 0028331487 scopus 로고
    • Central nervous system toxicity associated with meperidine use in hepatic disease
    • Danzinger LH, Martin SJ, Blum RA. Central nervous system toxicity associated with meperidine use in hepatic disease. Pharmacotherapy 1994; 14: 235-8
    • (1994) Pharmacotherapy , vol.14 , pp. 235-238
    • Danzinger, L.H.1    Martin, S.J.2    Blum, R.A.3
  • 113
    • 0029962074 scopus 로고    scopus 로고
    • Glucuronidation of amines and hydroxylated xenobiotics and endobiotics catalyzed by expressed human UGT1.4 protein
    • Green MD, Tephly TR. Glucuronidation of amines and hydroxylated xenobiotics and endobiotics catalyzed by expressed human UGT1.4 protein. Drug MetabDispos 1996; 24: 356-63
    • (1996) Drug MetabDispos , vol.24 , pp. 356-363
    • Green, M.D.1    Tephly, T.R.2
  • 114
    • 0029944684 scopus 로고    scopus 로고
    • Involvement of cytochrome P450 3A4 enzyme in the N-demethylation of methadone in human liver microsomes
    • Iribarne C, Berthou F, Baird S, et al. Involvement of cytochrome P450 3A4 enzyme in the N-demethylation of methadone in human liver microsomes. Chem Res Toxicol 1996; 9: 365-73
    • (1996) Chem Res Toxicol , vol.9 , pp. 365-373
    • Iribarne, C.1    Berthou, F.2    Baird, S.3
  • 115
    • 0023092375 scopus 로고
    • Pharmacokinetics and pharmacodynamics of methadone in patients with chronic pain
    • Inturrisi CE, Colburn WA, Kaiko RF, et al. Pharmacokinetics and pharmacodynamics of methadone in patients with chronic pain. Clin Pharmacol Ther 1987; 41: 392-401
    • (1987) Clin Pharmacol Ther , vol.41 , pp. 392-401
    • Inturrisi, C.E.1    Colburn, W.A.2    Kaiko, R.F.3
  • 117
    • 0023975281 scopus 로고
    • Naltrexone: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the management of opioid dependence
    • Gonzalez JP, Brogden RN. Naltrexone: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the management of opioid dependence. Drugs 1988; 35: 192-213
    • (1988) Drugs , vol.35 , pp. 192-213
    • Gonzalez, J.P.1    Brogden, R.N.2
  • 118
    • 0028998039 scopus 로고
    • Reduction of drug ketones by dihydrodiol dehydrogenases, carbonyl reductase and aldehyde reductase of human liver
    • Ohara H, Miyabe Y, Deyashiki Y, et al. Reduction of drug ketones by dihydrodiol dehydrogenases, carbonyl reductase and aldehyde reductase of human liver. Biochem Pharmacol 1995; 50: 221-7
    • (1995) Biochem Pharmacol , vol.50 , pp. 221-227
    • Ohara, H.1    Miyabe, Y.2    Deyashiki, Y.3
  • 119
    • 0030060305 scopus 로고    scopus 로고
    • Pharmacokinetic-pharmacodynamic relationships of controlled-release oxycodone
    • Kaiko RF, Benziger DP, Fitzmartin RD, et al. Pharmacokinetic-pharmacodynamic relationships of controlled-release oxycodone. Clin Pharmacol Ther 1996; 59: 52-61
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 52-61
    • Kaiko, R.F.1    Benziger, D.P.2    Fitzmartin, R.D.3
  • 120
    • 0020058383 scopus 로고
    • Propoxyphene and norpropoxyphene kinetics after single and repeated doses of propoxyphene
    • Inturrisi CE, Colbum WA, Verebey K. Propoxyphene and norpropoxyphene kinetics after single and repeated doses of propoxyphene. Clin Pharmacol Ther 1982; 31: 157-67
    • (1982) Clin Pharmacol Ther , vol.31 , pp. 157-167
    • Inturrisi, C.E.1    Colbum, W.A.2    Verebey, K.3
  • 121
    • 0025270510 scopus 로고
    • D-Propoxyphene is a potent inhibitor of debrisoquine, but not S-mephenytoin 4-hydroxylation in vivo
    • Sanz EJ, Bertilsson L. D-Propoxyphene is a potent inhibitor of debrisoquine, but not S-mephenytoin 4-hydroxylation in vivo. Ther Drug Monitor 1990; 12: 297-9
    • (1990) Ther Drug Monitor , vol.12 , pp. 297-299
    • Sanz, E.J.1    Bertilsson, L.2
  • 122
    • 0026649268 scopus 로고
    • The metabolism of tramadol by human liver microsomes
    • Paar WD, Frankus P, Dengler HJ. The metabolism of tramadol by human liver microsomes. Clin Invest 1992; 70: 708-10
    • (1992) Clin Invest , vol.70 , pp. 708-710
    • Paar, W.D.1    Frankus, P.2    Dengler, H.J.3
  • 123
    • 0027194499 scopus 로고
    • Tramadol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in acute and chronic pain states
    • Lee CR, McTavish D, Sorkin EM, Tramadol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in acute and chronic pain states. Drugs 1993; 46: 313-40
    • (1993) Drugs , vol.46 , pp. 313-340
    • Lee, C.R.1    McTavish, D.2    Sorkin, E.M.3
  • 124
    • 0027253615 scopus 로고
    • Oxidation of acetaminophen to N-acetyl-p-aminobenzoquinone imine by human CYP3A4
    • Thummel KE, Lee CA, Kunze KL, et al. Oxidation of acetaminophen to N-acetyl-p-aminobenzoquinone imine by human CYP3A4. Biochem Pharmacol 1993; 45: 1563-9
    • (1993) Biochem Pharmacol , vol.45 , pp. 1563-1569
    • Thummel, K.E.1    Lee, C.A.2    Kunze, K.L.3
  • 125
    • 0029058914 scopus 로고
    • Cytochrome P4502E1 inhibition by propylene glycol prevents acetaminophen (paracetamol) hepatotoxicity in mice without cytochrome P4501A2 inhibition
    • Thomsen MS, Loft S, Roberts DW, et al. Cytochrome P4502E1 inhibition by propylene glycol prevents acetaminophen (paracetamol) hepatotoxicity in mice without cytochrome P4501A2 inhibition. Pharmacol Toxicol 1995; 76: 395-9
    • (1995) Pharmacol Toxicol , vol.76 , pp. 395-399
    • Thomsen, M.S.1    Loft, S.2    Roberts, D.W.3
  • 126
    • 0029002112 scopus 로고
    • Cytotoxicity of acetaminophen in human cytochrome P4502E1-transfected hepG2 cells
    • Dai Y, I CA. Cytotoxicity of acetaminophen in human cytochrome P4502E1-transfected hepG2 cells. J Pharmacol Exp Ther 1995; 273: 1497-505
    • (1995) J Pharmacol Exp Ther , vol.273 , pp. 1497-1505
    • Dai, Y.1    I., C.A.2
  • 127
    • 0019606624 scopus 로고
    • Salicylate metabolite kinetics after several salicylates
    • Bochner F, Graham GG, Cham E, et al. Salicylate metabolite kinetics after several salicylates. Clin Pharmacol Ther 1981; 30: 266-75
    • (1981) Clin Pharmacol Ther , vol.30 , pp. 266-275
    • Bochner, F.1    Graham, G.G.2    Cham, E.3
  • 128
    • 0024799035 scopus 로고
    • Pharmacokinetics of nicotinic acid-salicylic acid interaction
    • Ding RW, Kolbe K, Merz B, et al. Pharmacokinetics of nicotinic acid-salicylic acid interaction. Clin Pharmacol Ther 1989; 46: 642-7
    • (1989) Clin Pharmacol Ther , vol.46 , pp. 642-647
    • Ding, R.W.1    Kolbe, K.2    Merz, B.3
  • 129
    • 0018574044 scopus 로고
    • The pharmacokinetics of diclofenac sodium following intravenous and oral administration
    • Willis JV, Kendall MJ, Flinn RM, et al. The pharmacokinetics of diclofenac sodium following intravenous and oral administration. Eur J Clin Pharmacol 1979; 16: 405-10
    • (1979) Eur J Clin Pharmacol , vol.16 , pp. 405-410
    • Willis, J.V.1    Kendall, M.J.2    Flinn, R.M.3
  • 130
    • 0027739383 scopus 로고
    • TB (CYP2C subfamily) in the actions of non-steroidal antiinflammatory drugs
    • TB (CYP2C subfamily) in the actions of non-steroidal antiinflammatory drugs. Drug Exp Clin Res 1993; 19: 189-95
    • (1993) Drug Exp Clin Res , vol.19 , pp. 189-195
    • Leemann, T.D.1    Transon, C.2    Bonnabry, P.3
  • 131
    • 0028590127 scopus 로고
    • Biochemistry and molecular biology of the human CYP2C subfamily
    • Goldstein JA, de Morias SMF. Biochemistry and molecular biology of the human CYP2C subfamily. Pharmacogenetics 1994; 4: 285-99
    • (1994) Pharmacogenetics , vol.4 , pp. 285-299
    • Goldstein, J.A.1    De Morias, S.M.F.2
  • 132
    • 0029010518 scopus 로고
    • Role of cytochrome P450 2C9 and an allelic variant in the 4-hydroxylation of (R)- And (S)-flurbiprofen
    • Tracy TS, Rosenbluth BW, Wrighton SA, et al. Role of cytochrome P450 2C9 and an allelic variant in the 4-hydroxylation of (R)- and (S)-flurbiprofen. Biochem Pharmacol 1995; 49: 1269-75
    • (1995) Biochem Pharmacol , vol.49 , pp. 1269-1275
    • Tracy, T.S.1    Rosenbluth, B.W.2    Wrighton, S.A.3
  • 133
    • 0028984776 scopus 로고
    • Clinical pharamcokinetics of flurbiprofen and its enantiomers
    • Davies NM. Clinical pharamcokinetics of flurbiprofen and its enantiomers. Clin Pharmacokinet 1995; 28: 100-14
    • (1995) Clin Pharmacokinet , vol.28 , pp. 100-114
    • Davies, N.M.1
  • 134
    • 0022216138 scopus 로고
    • Stereoselective disposition of ibuprofen enantiomers in man
    • Lee EJD, Williams K, Day R, et al. Stereoselective disposition of ibuprofen enantiomers in man. Br J Clin Pharmacol 1985; 19: 669-74
    • (1985) Br J Clin Pharmacol , vol.19 , pp. 669-674
    • Lee, E.J.D.1    Williams, K.2    Day, R.3
  • 136
    • 0025126914 scopus 로고
    • Clinical pharmacokinetics of ketoprofen and its enantiomers
    • Jamali F, Brocks DR. Clinical pharmacokinetics of ketoprofen and its enantiomers. Clin Pharmacokinet 1990; 19: 197-217
    • (1990) Clin Pharmacokinet , vol.19 , pp. 197-217
    • Jamali, F.1    Brocks, D.R.2
  • 137
    • 0028949835 scopus 로고
    • Stereoselective esterase activity of human serum albumin toward ketoprofen glucuronide
    • Dubois-Presle N, Lapicque F, Maurice M-H, et al. Stereoselective esterase activity of human serum albumin toward ketoprofen glucuronide. Mol Pharmacol 1995; 47: 647-63
    • (1995) Mol Pharmacol , vol.47 , pp. 647-663
    • Dubois-Presle, N.1    Lapicque, F.2    Maurice, M.-H.3
  • 138
    • 0026463604 scopus 로고
    • Clinical pharmacokinetics of ketorolac tromethamine
    • Brocks DR, Jamali F. Clinical pharmacokinetics of ketorolac tromethamine. Clin Pharmacokinet 1992; 23: 415-27
    • (1992) Clin Pharmacokinet , vol.23 , pp. 415-427
    • Brocks, D.R.1    Jamali, F.2
  • 139
    • 0026461041 scopus 로고
    • An overview of the clinical pharmacokinetics of nabumetone
    • Hyneck ML. An overview of the clinical pharmacokinetics of nabumetone. J Rheumatol 1992; 19: 20-4
    • (1992) J Rheumatol , vol.19 , pp. 20-24
    • Hyneck, M.L.1
  • 140
    • 0027173237 scopus 로고
    • The pharmacokinetics of naproxen, its metabolite O-desmethylnaproxen, and their acyl-glucuronides in humans, Effect of cimetidine
    • Vree TB, Van Den Biggelaar-Martea M, Verwey-Van Wissen CPWGM, et al. The pharmacokinetics of naproxen, its metabolite O-desmethylnaproxen, and their acyl-glucuronides in humans, Effect of cimetidine. Br J Clin Pharmacol 1993; 35: 467-72
    • (1993) Br J Clin Pharmacol , vol.35 , pp. 467-472
    • Vree, T.B.1    Van Den Biggelaar-Martea, M.2    Verwey-Van Wissen, C.P.W.G.M.3
  • 142
    • 0029916692 scopus 로고    scopus 로고
    • Cytochromes P450, 1A2, and 2C9 are responsible for the human hepatic O-demethylation of R- And S-naproxen
    • Miners JO, Coulter S, Tukey RH, et al. Cytochromes P450, 1A2, and 2C9 are responsible for the human hepatic O-demethylation of R- and S-naproxen. Biochem Pharmacol 1996; 51: 1003-8
    • (1996) Biochem Pharmacol , vol.51 , pp. 1003-1008
    • Miners, J.O.1    Coulter, S.2    Tukey, R.H.3
  • 143
    • 0028084863 scopus 로고
    • Pharmacokinetics of oxicam nonsteroidal anti-inflammatory agents
    • Olkkola KT, Brunetto AV, Mattila MJ. Pharmacokinetics of oxicam nonsteroidal anti-inflammatory agents. Clin Pharmacokinet 1994; 26: 107-20
    • (1994) Clin Pharmacokinet , vol.26 , pp. 107-120
    • Olkkola, K.T.1    Brunetto, A.V.2    Mattila, M.J.3
  • 144
    • 0025302889 scopus 로고
    • Clinical pharmacokinetics of drugs used in the treatment of gastrointestinal diseases (Pt II)
    • Lauritsen K, Laursen LS, Rask-Madsen J. Clinical pharmacokinetics of drugs used in the treatment of gastrointestinal diseases (Pt II). Clin Pharmacokinet 1990; 19: 94-125
    • (1990) Clin Pharmacokinet , vol.19 , pp. 94-125
    • Lauritsen, K.1    Laursen, L.S.2    Rask-Madsen, J.3
  • 145
    • 0027325128 scopus 로고
    • Pharmacokinetics and dialyzability of sulindac and metabolites in patients with end-stage renal failure
    • Ravis WR, Diskin CJ, Campagna KD, et al. Pharmacokinetics and dialyzability of sulindac and metabolites in patients with end-stage renal failure. J Clin Pharmacol 1993; 33: 527-34
    • (1993) J Clin Pharmacol , vol.33 , pp. 527-534
    • Ravis, W.R.1    Diskin, C.J.2    Campagna, K.D.3
  • 146
    • 0028300816 scopus 로고
    • Human liver carbamazepine metabolism: Role of CYP3A4 and CYP2C8 in 10, 11-epoxide formation
    • Kerr BM, Thummel KE, Wurden CJ, et al. Human liver carbamazepine metabolism: role of CYP3A4 and CYP2C8 in 10, 11-epoxide formation. Biochem Pharmacol 1994; 47: 1969-79
    • (1994) Biochem Pharmacol , vol.47 , pp. 1969-1979
    • Kerr, B.M.1    Thummel, K.E.2    Wurden, C.J.3
  • 147
    • 0028787051 scopus 로고
    • Cytochrome P450 isozymes and antiepileptic drug interactions
    • Levy RH. Cytochrome P450 isozymes and antiepileptic drug interactions. Epilepsia 1995; 36: S8-S13
    • (1995) Epilepsia , vol.36
    • Levy, R.H.1
  • 148
    • 0030030330 scopus 로고    scopus 로고
    • Concentration and effects of oral midazolam are greatly reduced in patients treated with carbamazepine or phenytoin
    • Backman JT, Olkkola KT, Ojala M, et al. Concentration and effects of oral midazolam are greatly reduced in patients treated with carbamazepine or phenytoin. Epilepsia 1996; 37: 253-7
    • (1996) Epilepsia , vol.37 , pp. 253-257
    • Backman, J.T.1    Olkkola, K.T.2    Ojala, M.3
  • 149
    • 0029071781 scopus 로고
    • Valproic acid-carbamazepine interaction: Is valproic acid a selective inhibitor of epoxide hydrolase?
    • Svinarov DA, Pippenger CE. Valproic acid-carbamazepine interaction: is valproic acid a selective inhibitor of epoxide hydrolase? Ther Drug Monitor 1995; 17: 217-20
    • (1995) Ther Drug Monitor , vol.17 , pp. 217-220
    • Svinarov, D.A.1    Pippenger, C.E.2
  • 150
    • 0026799461 scopus 로고
    • In vivo evidence that ethosuximide is a substrate for cytochrome P450IIIA
    • Bachman K, Chang AC, Greear V. In vivo evidence that ethosuximide is a substrate for cytochrome P450IIIA. Pharmacology 1992; 45: 121-8
    • (1992) Pharmacology , vol.45 , pp. 121-128
    • Bachman, K.1    Chang, A.C.2    Greear, V.3
  • 151
    • 0020286881 scopus 로고
    • Ethosuximide kinetics: Possible interaction with valproic acid
    • Bauer LA, Harris C, Wilensky AJ, et al. Ethosuximide kinetics: possible interaction with valproic acid. Clin Pharmacol Ther 1982; 31: 741-5
    • (1982) Clin Pharmacol Ther , vol.31 , pp. 741-745
    • Bauer, L.A.1    Harris, C.2    Wilensky, A.J.3
  • 152
    • 0027223706 scopus 로고
    • Comparative pharmacokinetics of the newer antiepileptic drugs
    • Bialer M. Comparative pharmacokinetics of the newer antiepileptic drugs. Clin Pharmacokinet 1993; 24: 441-52
    • (1993) Clin Pharmacokinet , vol.24 , pp. 441-452
    • Bialer, M.1
  • 153
    • 0026005583 scopus 로고
    • Pharmacokinetics and safety of lamotrigine (Lamictal) in patients with epilepsy
    • Ramsay RE, Pellock JM, Garnett WR. Pharmacokinetics and safety of lamotrigine (Lamictal) in patients with epilepsy. Epilepsy Res 1991; 10: 191-200
    • (1991) Epilepsy Res , vol.10 , pp. 191-200
    • Ramsay, R.E.1    Pellock, J.M.2    Garnett, W.R.3
  • 154
    • 0028818418 scopus 로고
    • Effects of felbamate on the pharmacokinetics of phenobarbital
    • Reidenberg P, Glue P, Banfield CR, et al. Effects of felbamate on the pharmacokinetics of phenobarbital. Clin Pharmacol Ther 1995; 58: 279-87
    • (1995) Clin Pharmacol Ther , vol.58 , pp. 279-287
    • Reidenberg, P.1    Glue, P.2    Banfield, C.R.3
  • 155
    • 0029872471 scopus 로고    scopus 로고
    • Distinct effects of phenobarbital and its n-methylated derivative on liver cytochrome P450 induction
    • Murayama N, Shimada M, Yamazoe Y, et al. Distinct effects of phenobarbital and its n-methylated derivative on liver cytochrome P450 induction. Arch Biochem Biophys 1996; 328: 184-92
    • (1996) Arch Biochem Biophys , vol.328 , pp. 184-192
    • Murayama, N.1    Shimada, M.2    Yamazoe, Y.3
  • 156
    • 0029033092 scopus 로고
    • Effect of model inducers on cytochrome P450 activities of human liver hepatocytes in primary culture
    • Donato MT, Castell JV, Gómez-Lechón MJ. Effect of model inducers on cytochrome P450 activities of human liver hepatocytes in primary culture. Drug Metab Dispos 1995; 23: 553-8
    • (1995) Drug Metab Dispos , vol.23 , pp. 553-558
    • Donato, M.T.1    Castell, J.V.2    Gómez-Lechón, M.J.3
  • 157
    • 0022212549 scopus 로고
    • Stereoselective mephobarbital hydroxylation cosegregates with mephenytoin hydroxylation
    • Kupfer A, Branch RA. Stereoselective mephobarbital hydroxylation cosegregates with mephenytoin hydroxylation. Clin Pharmacol Ther 1985; 38: 414-8
    • (1985) Clin Pharmacol Ther , vol.38 , pp. 414-418
    • Kupfer, A.1    Branch, R.A.2
  • 158
    • 0026058222 scopus 로고
    • Relationship between phenytoin and tolbutamide hydroxylalions in human liver microsomes
    • Doecke CJ, Veronese ME, Pond SM, et al. Relationship between phenytoin and tolbutamide hydroxylalions in human liver microsomes. Br J Clin Pharmacol 1991; 31: 125-30
    • (1991) Br J Clin Pharmacol , vol.31 , pp. 125-130
    • Doecke, C.J.1    Veronese, M.E.2    Pond, S.M.3
  • 159
    • 0029595358 scopus 로고
    • Itraconazole and hydroxyitraconazole serum concentrations are reduced more than tenfold by phenytoin
    • Ducharme MP, Slaughter RL, Warbasse LH, et al. Itraconazole and hydroxyitraconazole serum concentrations are reduced more than tenfold by phenytoin. Clin Pharmacol Ther 1995; 58: 617-24
    • (1995) Clin Pharmacol Ther , vol.58 , pp. 617-624
    • Ducharme, M.P.1    Slaughter, R.L.2    Warbasse, L.H.3
  • 160
    • 0025222932 scopus 로고
    • Therapeutic drug monitoring of phenytoin: Rationale and current status
    • Levine M, Chang T. Therapeutic drug monitoring of phenytoin: rationale and current status. Clin Pharmacokinet 1990; 19: 341-58
    • (1990) Clin Pharmacokinet , vol.19 , pp. 341-358
    • Levine, M.1    Chang, T.2
  • 162
    • 0028045747 scopus 로고
    • Valproic acid. A reappraisal of its pharmacological properties and clinical efficacy in epilepsy
    • Davis R, Peters DH, McTavish D. Valproic acid. A reappraisal of its pharmacological properties and clinical efficacy in epilepsy. Drugs 1994; 47: 332-72
    • (1994) Drugs , vol.47 , pp. 332-372
    • Davis, R.1    Peters, D.H.2    McTavish, D.3
  • 163
    • 0029079640 scopus 로고
    • CYP4 isozyme specificity and the relationship between ω-hydroxylation and terminal desaturation of valproic acid
    • Rettie AE, Sheffels PR, Korzekwa KR, et al. CYP4 isozyme specificity and the relationship between ω-hydroxylation and terminal desaturation of valproic acid. Biochemistry 1995; 34: 7889-95
    • (1995) Biochemistry , vol.34 , pp. 7889-7895
    • Rettie, A.E.1    Sheffels, P.R.2    Korzekwa, K.R.3
  • 164
    • 0020549610 scopus 로고
    • Influence of age on amikacin pharmacokinetics in patients without renal disease, comparison with gentamicin and tobramycin
    • Bauer LA, Blouin RA. Influence of age on amikacin pharmacokinetics in patients without renal disease, comparison with gentamicin and tobramycin. Eur J Clin Pharmacol 1983; 24: 639-42
    • (1983) Eur J Clin Pharmacol , vol.24 , pp. 639-642
    • Bauer, L.A.1    Blouin, R.A.2
  • 165
    • 0022995887 scopus 로고
    • Intra- And inter-individual variation in pharmacokinetics of intravenously infused amoxycillin and ampicillin to elderly volunteers
    • Sjövall J, Alván G, Huitfeldt B. Intra- and inter-individual variation in pharmacokinetics of intravenously infused amoxycillin and ampicillin to elderly volunteers. Br J Clin Pharmacol 1986; 21: 171-81
    • (1986) Br J Clin Pharmacol , vol.21 , pp. 171-181
    • Sjövall, J.1    Alván, G.2    Huitfeldt, B.3
  • 166
    • 0027370119 scopus 로고
    • Azithromycin: Clinical pharmacokinetics
    • Lalak NJ, Morris DL. Azithromycin: clinical pharmacokinetics. Clin Pharmacokinet 1993; 25: 370-4
    • (1993) Clin Pharmacokinet , vol.25 , pp. 370-374
    • Lalak, N.J.1    Morris, D.L.2
  • 167
    • 0026766219 scopus 로고
    • Pharmacokinetic drug interactions of macrolides
    • Periti P, Mazzei T, Mini E, et al. Pharmacokinetic drug interactions of macrolides. Clin Pharmacokinet 1992; 23: 106-31
    • (1992) Clin Pharmacokinet , vol.23 , pp. 106-131
    • Periti, P.1    Mazzei, T.2    Mini, E.3
  • 168
    • 0027440142 scopus 로고
    • Pharmacokinetic drug interactions with antimicrobial agents
    • Gillum JG, Israel DS, Polk RE. Pharmacokinetic drug interactions with antimicrobial agents. Clin Pharmacokinet 1993; 25: 450-82
    • (1993) Clin Pharmacokinet , vol.25 , pp. 450-482
    • Gillum, J.G.1    Israel, D.S.2    Polk, R.E.3
  • 170
    • 13644250037 scopus 로고
    • The effects of quinolones on xanthine pharmacokinetics
    • Robson RA. The effects of quinolones on xanthine pharmacokinetics. Am J Med 1992; 92: 22S-25S
    • (1992) Am J Med , vol.92
    • Robson, R.A.1
  • 171
    • 0030031716 scopus 로고    scopus 로고
    • Quinolones: A practical review of clinical uses, dosing considerations, and drug interactions
    • Borcherding SM, Stevens R, Nicholas RA, et al. Quinolones: a practical review of clinical uses, dosing considerations, and drug interactions. J Fam Prac 1996; 42: 69-78
    • (1996) J Fam Prac , vol.42 , pp. 69-78
    • Borcherding, S.M.1    Stevens, R.2    Nicholas, R.A.3
  • 173
    • 0024516261 scopus 로고
    • Pharmacokinetic disposition of quinolones in human body fluids and tissues
    • Sörgel F, Jaehde U, Naber K, et al. Pharmacokinetic disposition of quinolones in human body fluids and tissues. Clin Pharmacokinet 1989; 16: 5-24
    • (1989) Clin Pharmacokinet , vol.16 , pp. 5-24
    • Sörgel, F.1    Jaehde, U.2    Naber, K.3
  • 176
    • 0028915901 scopus 로고
    • Reduced serum levels of clarithromycin in patients treated with multidrug regimens including rifampin or rifabutin for Mycobacterium avium-M. intracellulare infection
    • Wallace RJ, Brown BA, Griffith DE, et al. Reduced serum levels of clarithromycin in patients treated with multidrug regimens including rifampin or rifabutin for Mycobacterium avium-M. intracellulare infection. J Infect Dis 1995; 171: 747-50
    • (1995) J Infect Dis , vol.171 , pp. 747-750
    • Wallace, R.J.1    Brown, B.A.2    Griffith, D.E.3
  • 177
    • 0024557286 scopus 로고
    • Pharmacokinetic evaluation of two dosage regimens of clindamycin phosphate
    • Plaisance KI, Drusano GL, Forrest A, et al. Pharmacokinetic evaluation of two dosage regimens of clindamycin phosphate. Antimicrob Agents Chemother 1989; 33: 618-20
    • (1989) Antimicrob Agents Chemother , vol.33 , pp. 618-620
    • Plaisance, K.I.1    Drusano, G.L.2    Forrest, A.3
  • 178
    • 0027278550 scopus 로고
    • Pharmacokinetic optimisation in the treatment of Pneumocystis carinii pneumonia
    • Vöhringer H-F, Arastéh K. Pharmacokinetic optimisation in the treatment of Pneumocystis carinii pneumonia. Clin Pharmacokinet 1993; 24: 388-412
    • (1993) Clin Pharmacokinet , vol.24 , pp. 388-412
    • Vöhringer, H.-F.1    Arastéh, K.2
  • 179
    • 0020384294 scopus 로고
    • Pharmacokinetics of tetracycline in nutritional ocdema
    • Raghuram TC, Krishnaswamy K. Pharmacokinetics of tetracycline in nutritional ocdema. Chemotherapy 1982; 28: 428-33
    • (1982) Chemotherapy , vol.28 , pp. 428-433
    • Raghuram, T.C.1    Krishnaswamy, K.2
  • 180
    • 0024271676 scopus 로고
    • Clinical pharmacokinetics of doxycycline and minocycline
    • Saivin S, Houin G. Clinical pharmacokinetics of doxycycline and minocycline. Clin Pharmacokinet 1988; 15: 355-66
    • (1988) Clin Pharmacokinet , vol.15 , pp. 355-366
    • Saivin, S.1    Houin, G.2
  • 181
    • 0028847788 scopus 로고
    • The erythromycin breath test predicts the clearance of midazolam
    • Lown KS, Thummel KE, Benedict PE, et al. The erythromycin breath test predicts the clearance of midazolam. Clin Pharmacol Ther 1995: 16-24
    • (1995) Clin Pharmacol Ther , pp. 16-24
    • Lown, K.S.1    Thummel, K.E.2    Benedict, P.E.3
  • 182
    • 0026601064 scopus 로고
    • Heterogeneity of CYP3A isoforms metabolizing erythromycin and cortisol
    • Hunt CM, Watkins PB, Saenger P, et al. Heterogeneity of CYP3A isoforms metabolizing erythromycin and cortisol. Clin Pharmacol Ther 1992; 51: 18-23
    • (1992) Clin Pharmacol Ther , vol.51 , pp. 18-23
    • Hunt, C.M.1    Watkins, P.B.2    Saenger, P.3
  • 183
    • 0030029958 scopus 로고    scopus 로고
    • Erythromycin as a specific substrate for cytochrome P4503A isozymes and identification of a high-affinity erythromycin N-demethylase in adult female rats
    • Zhang X-J, Thomas PE. Erythromycin as a specific substrate for cytochrome P4503A isozymes and identification of a high-affinity erythromycin N-demethylase in adult female rats. Drug Metab Dispos 1996; 24: 23-7
    • (1996) Drug Metab Dispos , vol.24 , pp. 23-27
    • Zhang, X.-J.1    Thomas, P.E.2
  • 184
    • 0026768843 scopus 로고
    • Imipenem/cilastatin: A reappraisal of its antibacterial activity, pharmacokinetic properties and therapeutic efficacy
    • Buckley MM, Brogden RN, Barradell LB, et al. Imipenem/cilastatin: a reappraisal of its antibacterial activity, pharmacokinetic properties and therapeutic efficacy. Drugs 1992; 44: 408-44
    • (1992) Drugs , vol.44 , pp. 408-444
    • Buckley, M.M.1    Brogden, R.N.2    Barradell, L.B.3
  • 185
    • 0026666065 scopus 로고
    • Clinical pharmacokinetics of metronidazole and other nitroimidazole anti-infectives
    • Lau AH, Lam NP, Piscitelli SC, et al. Clinical pharmacokinetics of metronidazole and other nitroimidazole anti-infectives. Clin Pharmacokinet 1992; 23: 328-64
    • (1992) Clin Pharmacokinet , vol.23 , pp. 328-364
    • Lau, A.H.1    Lam, N.P.2    Piscitelli, S.C.3
  • 186
    • 0017700655 scopus 로고
    • Disposition of nafcillin in patients with cirrhosis and extrahepatic biliary obstruction
    • Marshall JP II, Salt WB, Elam RO, et al. Disposition of nafcillin in patients with cirrhosis and extrahepatic biliary obstruction. Gastroenterology 1977; 73: 1388-92
    • (1977) Gastroenterology , vol.73 , pp. 1388-1392
    • Marshall II, J.P.1    Salt, W.B.2    Elam, R.O.3
  • 187
    • 0014650758 scopus 로고
    • Pharmacokinetic interpretation of penicillin levels in serum and urine after intravenous administration
    • Dittert LW, Griffen WO Jr, LaPiana JC, et al. Pharmacokinetic interpretation of penicillin levels in serum and urine after intravenous administration. Antimicrob Agents Chemother 1969; 9: 42-8
    • (1969) Antimicrob Agents Chemother , vol.9 , pp. 42-48
    • Dittert, L.W.1    Griffen Jr., W.O.2    LaPiana, J.C.3
  • 189
    • 0025256091 scopus 로고
    • Amphotericin B: 30 years of clinical experience
    • Gallis HA, Drew RH, Pickard WW. Amphotericin B: 30 years of clinical experience. Rev Infect Dis 1990; 12: 308-29
    • (1990) Rev Infect Dis , vol.12 , pp. 308-329
    • Gallis, H.A.1    Drew, R.H.2    Pickard, W.W.3
  • 191
    • 0023253045 scopus 로고
    • A comparative trial of clotrimazole troches and oral nystatin suspension in recipients of renal transplants. Use in prophylaxix of oropharyngeal candidiasis
    • Gombert ME, DuBouchet L, Aulicino TM, et al. A comparative trial of clotrimazole troches and oral nystatin suspension in recipients of renal transplants. Use in prophylaxix of oropharyngeal candidiasis. JAMA 1987; 258: 2553-5
    • (1987) JAMA , vol.258 , pp. 2553-2555
    • Gombert, M.E.1    DuBouchet, L.2    Aulicino, T.M.3
  • 193
    • 0029877219 scopus 로고    scopus 로고
    • Warfarin-Fluconazole I: Inhibition of the human cytochrome P450-dependent metabolism of warfarin by fluconazole: in vitro studies
    • Kunze KL, Weinkers LC, Thummel KE, et al. Warfarin-Fluconazole I: inhibition of the human cytochrome P450-dependent metabolism of warfarin by fluconazole: in vitro studies. Drug Metab Dispos 1996; 24: 414-21
    • (1996) Drug Metab Dispos , vol.24 , pp. 414-421
    • Kunze, K.L.1    Weinkers, L.C.2    Thummel, K.E.3
  • 194
    • 0029996292 scopus 로고    scopus 로고
    • Warfarin-Fluconazole II: A metabolically based drug interaction: in vivo studies
    • Black DJ, Kunze KL, Wienkers LC, et al. Warfarin-Fluconazole II: a metabolically based drug interaction: in vivo studies. Drug Metab Dispos 1996; 24: 422-8
    • (1996) Drug Metab Dispos , vol.24 , pp. 422-428
    • Black, D.J.1    Kunze, K.L.2    Wienkers, L.C.3
  • 196
    • 0028970047 scopus 로고
    • Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9
    • Baldwin SJ, Bloomer JC, Smith GJ, et al. Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9. Xenobiotica 1995; 25: 261-70
    • (1995) Xenobiotica , vol.25 , pp. 261-270
    • Baldwin, S.J.1    Bloomer, J.C.2    Smith, G.J.3
  • 197
    • 0029131555 scopus 로고
    • Clinical importance of hepatic cytochrome P450 in drug metabolism
    • Spatzenegger M, Jaeger W. Clinical importance of hepatic cytochrome P450 in drug metabolism. Drug Metab Rev 1995; 27: 397-417
    • (1995) Drug Metab Rev , vol.27 , pp. 397-417
    • Spatzenegger, M.1    Jaeger, W.2
  • 198
    • 0023571651 scopus 로고
    • The pharmacokinetics of ketoconazole after chronic administration in adults
    • Badcock NR, Bartholomeusz FD, Frewin DB, et al. The pharmacokinetics of ketoconazole after chronic administration in adults. Eur J Clin Pharmacol 1987; 33: 531-4
    • (1987) Eur J Clin Pharmacol , vol.33 , pp. 531-534
    • Badcock, N.R.1    Bartholomeusz, F.D.2    Frewin, D.B.3
  • 199
    • 0029920875 scopus 로고    scopus 로고
    • Clinical observations of metabolic changes occurring in renal transplant recipients receiving ketoconazole
    • Moore LW, Alloway RR, Acchiardo SR, et al. Clinical observations of metabolic changes occurring in renal transplant recipients receiving ketoconazole. Transplantation 1996; 61: 537-41
    • (1996) Transplantation , vol.61 , pp. 537-541
    • Moore, L.W.1    Alloway, R.R.2    Acchiardo, S.R.3
  • 200
    • 0026763432 scopus 로고
    • Mechanisms of the stereoselective interaction between miconazole and racemic warfarin in human subjects
    • OReilly RA, Goulart DA, Kunze KL, et al. Mechanisms of the stereoselective interaction between miconazole and racemic warfarin in human subjects. Clin Pharmacol Ther 1992; 51: 656-7
    • (1992) Clin Pharmacol Ther , vol.51 , pp. 656-657
    • Oreilly, R.A.1    Goulart, D.A.2    Kunze, K.L.3
  • 201
    • 0026592286 scopus 로고
    • Azoles, allylamines and drug metabolism
    • Back DJ, Tha JF, Abel SM. Azoles, allylamines and drug metabolism. Br J Dermatol 1992; 126: 14-8
    • (1992) Br J Dermatol , vol.126 , pp. 14-18
    • Back, D.J.1    Tha, J.F.2    Abel, S.M.3
  • 202
    • 0028832737 scopus 로고
    • Pharmacokinetics of terbinafine and of its five main metabolites in plasma and urine, following a single oral dose in healthy subjects
    • Humbert H, Cabiac MD, Denouèl J, et al. Pharmacokinetics of terbinafine and of its five main metabolites in plasma and urine, following a single oral dose in healthy subjects. Biopharm Drug Dispos 1995; 16: 685-94
    • (1995) Biopharm Drug Dispos , vol.16 , pp. 685-694
    • Humbert, H.1    Cabiac, M.D.2    Denouèl, J.3
  • 203
    • 0026556493 scopus 로고
    • Dose-proportional pharmacokinetics of terbinafine and its N-demethylated metabolite in healthy volunteers
    • Kovarik JM, Kirkesseli S, Humbert H, et al. Dose-proportional pharmacokinetics of terbinafine and its N-demethylated metabolite in healthy volunteers. Br J Dermatol 1992; 126: 8-13
    • (1992) Br J Dermatol , vol.126 , pp. 8-13
    • Kovarik, J.M.1    Kirkesseli, S.2    Humbert, H.3
  • 204
    • 0028840511 scopus 로고
    • Multiple-dose pharmacokinetics and distribution in tissue of terbinafine and metabolites
    • Kovarik JM, Mueller E, A., Zehender H, et al. Multiple-dose pharmacokinetics and distribution in tissue of terbinafine and metabolites. Antimicrob Agents Chemother 1995; 39: 2738-41
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 2738-2741
    • Kovarik, J.M.1    Mueller, E.A.2    Zehender, H.3
  • 205
    • 0025829277 scopus 로고
    • Clofazimine: A review of its use in leprosy and Mycobacterium avium complex infection
    • Garrelts JC. Clofazimine: A review of its use in leprosy and Mycobacterium avium complex infection. DICP Ann Pharmacother 1991; 25: 525-31
    • (1991) DICP Ann Pharmacother , vol.25 , pp. 525-531
    • Garrelts, J.C.1
  • 206
    • 0021711632 scopus 로고
    • Clinical pharmacokinetics of the antituberculosis drugs
    • Holdiness MR. Clinical pharmacokinetics of the antituberculosis drugs. Clin Pharmacokinet 1984; 9: 511-44
    • (1984) Clin Pharmacokinet , vol.9 , pp. 511-544
    • Holdiness, M.R.1
  • 207
    • 0023550902 scopus 로고
    • Pharmacokinetics of antituberculosis drugs in patients
    • Israili ZH, Rogers CM, El-Attar H. Pharmacokinetics of antituberculosis drugs in patients. J Clin Pharmacol 1987; 27: 78-83
    • (1987) J Clin Pharmacol , vol.27 , pp. 78-83
    • Zh, I.1    Rogers, C.M.2    El-Attar, H.3
  • 208
    • 0027163604 scopus 로고
    • Inhibition and induction of cytochrome P4502E1-catalyzed oxidation by isoniazid in humans
    • Zand R, Nelson SD, Slattery JT, et al. Inhibition and induction of cytochrome P4502E1-catalyzed oxidation by isoniazid in humans. Clin Pharmacol Ther 1993; 54: 142-9
    • (1993) Clin Pharmacol Ther , vol.54 , pp. 142-149
    • Zand, R.1    Nelson, S.D.2    Slattery, J.T.3
  • 209
    • 0026599779 scopus 로고
    • Pharmacogenetics: Part I
    • Gibaldi M. Pharmacogenetics: Part I. Ann Pharmacother 1992; 26: 121-6
    • (1992) Ann Pharmacother , vol.26 , pp. 121-126
    • Gibaldi, M.1
  • 210
    • 0029070017 scopus 로고    scopus 로고
    • In vitro and in vivo study on the conversion of allopurinol and pyrazinamide
    • Nasako Y, Yamamoto T, Moriwaki Y, et al. In vitro and in vivo study on the conversion of allopurinol and pyrazinamide. Adv Exp Med Biol 1996; 370: 43-6
    • (1996) Adv Exp Med Biol , vol.370 , pp. 43-46
    • Nasako, Y.1    Yamamoto, T.2    Moriwaki, Y.3
  • 211
    • 0030055907 scopus 로고    scopus 로고
    • The clinical pharmacokinetics of rifabutin
    • Blaschke TF, Skinner MH. The clinical pharmacokinetics of rifabutin. Clin Infect Dis 1996; 22: S15-S22
    • (1996) Clin Infect Dis , vol.22
    • Blaschke, T.F.1    Skinner, M.H.2
  • 212
    • 0028567499 scopus 로고
    • Induction and autoinduction properties of rifamycin derivatives: A review of animal and human studies
    • Benedetti MS, Dostert P. Induction and autoinduction properties of rifamycin derivatives: A review of animal and human studies. Environ Health Perspect 1994; 109: 101-5
    • (1994) Environ Health Perspect , vol.109 , pp. 101-105
    • Benedetti, M.S.1    Dostert, P.2
  • 213
    • 0026695073 scopus 로고
    • Two- And four-day rifampin chemoprophylaxis regimens induce oxidative metabolism
    • Borcherding SM, Bastian TL, Self TH, et al. Two- and four-day rifampin chemoprophylaxis regimens induce oxidative metabolism. Antimicrob Agents Chemother 1992; 36: 1553-8
    • (1992) Antimicrob Agents Chemother , vol.36 , pp. 1553-1558
    • Borcherding, S.M.1    Bastian, T.L.2    Self, T.H.3
  • 214
    • 0030068752 scopus 로고    scopus 로고
    • Rifampin drastically reduces plasma concentrations and effects of oral midazolam
    • Backman JT, Olkkola KT, Neuvonen PJ. Rifampin drastically reduces plasma concentrations and effects of oral midazolam. Clin Pharmacol Ther 1996; 59: 7-13
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 7-13
    • Backman, J.T.1    Olkkola, K.T.2    Neuvonen, P.J.3
  • 217
    • 0029009850 scopus 로고
    • Small intestinal sulphoxidation of albendazole
    • Villaverde C, Alvarez AI, Redondo P, et al. Small intestinal sulphoxidation of albendazole. Xenobiotica 1995; 25: 433-41
    • (1995) Xenobiotica , vol.25 , pp. 433-441
    • Villaverde, C.1    Alvarez, A.I.2    Redondo, P.3
  • 218
    • 0028812229 scopus 로고
    • Chiral sulfoxidation of albendazole by the flavin adenine dinucleotide-containing and cytochrome P450-dependent monoxygenases from rat liver microsomes
    • Moroni P, Buronfosse T, Longin-Sauvageon C, et al. Chiral sulfoxidation of albendazole by the flavin adenine dinucleotide-containing and cytochrome P450-dependent monoxygenases from rat liver microsomes. Drug Metab Dispos 1995; 23: 160-5
    • (1995) Drug Metab Dispos , vol.23 , pp. 160-165
    • Moroni, P.1    Buronfosse, T.2    Longin-Sauvageon, C.3
  • 219
    • 0028998292 scopus 로고
    • Atovaquone. A review of its pharmacological properties and therapeutic efficacy in opportunistic infections
    • Spencer CM, Goa KL. Atovaquone. A review of its pharmacological properties and therapeutic efficacy in opportunistic infections. Drugs 1995; 50: 176-96
    • (1995) Drugs , vol.50 , pp. 176-196
    • Spencer, C.M.1    Goa, K.L.2
  • 220
    • 0030069046 scopus 로고    scopus 로고
    • Atovaquone inhibits the glucuronidation and increases the plasma concentrations of zidovudine
    • Lee BL, Täuber MG, Sadler B, et al. Atovaquone inhibits the glucuronidation and increases the plasma concentrations of zidovudine. Clin Pharmacol Ther 1996; 59: 14-21
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 14-21
    • Lee, B.L.1    Täuber, M.G.2    Sadler, B.3
  • 222
    • 0030007219 scopus 로고    scopus 로고
    • Pharmacokinetics of quinine, chloroquine and amodiaquine. Clinical implications
    • Krishna S, White NJ. Pharmacokinetics of quinine, chloroquine and amodiaquine. Clinical implications. Clin Pharmacokinet 1996; 30: 263-99
    • (1996) Clin Pharmacokinet , vol.30 , pp. 263-299
    • Krishna, S.1    White, N.J.2
  • 223
    • 0029819068 scopus 로고    scopus 로고
    • Clinical pharmacokinetics and metabolism of chloroquine. Focus on recent advancements
    • Ducharme J, Farinotti R. Clinical pharmacokinetics and metabolism of chloroquine. Focus on recent advancements. Clin Pharmacokinet 1996; 31: 257-74
    • (1996) Clin Pharmacokinet , vol.31 , pp. 257-274
    • Ducharme, J.1    Farinotti, R.2
  • 224
    • 0028917691 scopus 로고
    • Dapsone acetylation by human liver arylamine N-acetyltransferases and interaction with antiopportunistic infection drugs
    • Palamanda JR, Hickman D, Ward A, et al. Dapsone acetylation by human liver arylamine N-acetyltransferases and interaction with antiopportunistic infection drugs. Drug Metab Dispos 1995; 23: 473-7
    • (1995) Drug Metab Dispos , vol.23 , pp. 473-477
    • Palamanda, J.R.1    Hickman, D.2    Ward, A.3
  • 225
    • 0028839899 scopus 로고
    • Metabolism of dapsone to its hydroxylamine by CYP2E1 in vitro and in vivo
    • Mitra AK, Thummel KE, Kalhorn T, et al. Metabolism of dapsone to its hydroxylamine by CYP2E1 in vitro and in vivo. Clin Pharmacol Ther 1995; 58: 556-66
    • (1995) Clin Pharmacol Ther , vol.58 , pp. 556-566
    • Mitra, A.K.1    Thummel, K.E.2    Kalhorn, T.3
  • 226
    • 0029416939 scopus 로고
    • N-Hydroxylation of dapsone by multiple enzymes of cytochrome P450: Implications for inhibition of haemotoxicity
    • Gill HJ, Tingle MD, Park BK. N-Hydroxylation of dapsone by multiple enzymes of cytochrome P450: Implications for inhibition of haemotoxicity. Br J Clin Pharmacol 1995; 40: 531-8
    • (1995) Br J Clin Pharmacol , vol.40 , pp. 531-538
    • Gill, H.J.1    Tingle, M.D.2    Park, B.K.3
  • 227
    • 0030060304 scopus 로고    scopus 로고
    • Comparison of the dapsone recovery ratio and the erythromycin breath test as in vivo probes of CYP3A activity in patients with rheumatoid arthritis receiving cyclosporine
    • Stein CM, Kinirons MT, Pincus T, et al. Comparison of the dapsone recovery ratio and the erythromycin breath test as in vivo probes of CYP3A activity in patients with rheumatoid arthritis receiving cyclosporine. Clin Pharmacol Ther 1996; 59: 47-51
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 47-51
    • Stein, C.M.1    Kinirons, M.T.2    Pincus, T.3
  • 228
    • 0026056370 scopus 로고
    • Pharmacokinetic justification of antiprotozoal therapy: A US perspective
    • Berman JD, Fleckenstein L. Pharmacokinetic justification of antiprotozoal therapy: A US perspective. Clin Pharmacokinet 1991; 21: 479-92
    • (1991) Clin Pharmacokinet , vol.21 , pp. 479-492
    • Berman, J.D.1    Fleckenstein, L.2
  • 229
    • 0027396392 scopus 로고
    • Ivermectin, an antiparasitic agent
    • Campbell WC. Ivermectin, an antiparasitic agent. Med Res Rev 1993; 13: 61-79
    • (1993) Med Res Rev , vol.13 , pp. 61-79
    • Campbell, W.C.1
  • 231
    • 0019389490 scopus 로고
    • Chemotherapy of alveolar echinococcosis: Comparison of plasma mebendazole concentrations in animals and man
    • Witassek F, Burkhardt B, Eckert J, et al. Chemotherapy of alveolar echinococcosis: comparison of plasma mebendazole concentrations in animals and man. Eur J Clin Pharmacokin 1981; 20: 427-33
    • (1981) Eur J Clin Pharmacokin , vol.20 , pp. 427-433
    • Witassek, F.1    Burkhardt, B.2    Eckert, J.3
  • 232
    • 0020065571 scopus 로고
    • Clinical pharmacokinetics of high dose mebendazole in patients treated for cystic hydatid disease
    • Braithwaite PA, Roberts MS, Allan RJ, et al. Clinical pharmacokinetics of high dose mebendazole in patients treated for cystic hydatid disease. Eur J Clin Pharmacol 1982; 22: 161-9
    • (1982) Eur J Clin Pharmacol , vol.22 , pp. 161-169
    • Braithwaite, P.A.1    Roberts, M.S.2    Allan, R.J.3
  • 233
    • 0027403103 scopus 로고
    • Mefloquine: A review of its antimalarial activity, pharmacokinetic properties and therapeutic efficacy
    • Palmer KJ, Holliday SM, Brogden RN. Mefloquine: a review of its antimalarial activity, pharmacokinetic properties and therapeutic efficacy. Drugs 1993; 45: 430-75
    • (1993) Drugs , vol.45 , pp. 430-475
    • Palmer, K.J.1    Holliday, S.M.2    Brogden, R.N.3
  • 234
    • 0027968269 scopus 로고
    • Clinical pharmacokinetics in the treatment of tropical diseases: Some applications and limitations
    • Edwards G, Winstanley PA, Ward SA. Clinical pharmacokinetics in the treatment of tropical diseases: some applications and limitations. Clin Pharmacokinet 1994; 27: 150-65
    • (1994) Clin Pharmacokinet , vol.27 , pp. 150-165
    • Edwards, G.1    Winstanley, P.A.2    Ward, S.A.3
  • 235
    • 0027931671 scopus 로고
    • Absence of systemic absorption of oral paromomycin during long-term, high-dose treatment for cryptosporidiosis in AIDS (5)
    • Bissuel F, Cotte L, De Montclos M, et al. Absence of systemic absorption of oral paromomycin during long-term, high-dose treatment for cryptosporidiosis in AIDS (5). J Infect Dis 1994; 170: 749-50
    • (1994) J Infect Dis , vol.170 , pp. 749-750
    • Bissuel, F.1    Cotte, L.2    De Montclos, M.3
  • 236
    • 0026099160 scopus 로고
    • Pharmacokinetics of intravenous pentamidine in patients with normal renal function or receiving hemodialysis
    • Conte Jr JE. Pharmacokinetics of intravenous pentamidine in patients with normal renal function or receiving hemodialysis. J Infect Dis 1991; 163: 169-75
    • (1991) J Infect Dis , vol.163 , pp. 169-175
    • Conte Jr., J.E.1
  • 237
    • 0024582705 scopus 로고
    • Drugs five years later: Praziquantel
    • King CH, Mahmoud AAF. Drugs five years later: praziquantel. Ann Intern Med 1989; 110: 290-6
    • (1989) Ann Intern Med , vol.110 , pp. 290-296
    • King, C.H.1    Mahmoud, A.A.F.2
  • 239
    • 0021229470 scopus 로고
    • Pharmacokinetics of primaquine in man: Identification of the carboxylic acid derivative as a major plasma metabolite
    • Mihaly GW, Ward SA, Edwards G, et al. Pharmacokinetics of primaquine in man: identification of the carboxylic acid derivative as a major plasma metabolite. Br J Clin Pharmacokinet 1984; 17: 441-6
    • (1984) Br J Clin Pharmacokinet , vol.17 , pp. 441-446
    • Mihaly, G.W.1    Ward, S.A.2    Edwards, G.3
  • 240
    • 0028903810 scopus 로고
    • The role of S-mephenytoin hydroxylase (CYP2C19) in the metabolism of the antimalarial biguanides
    • Wright JD, Helsby NA, Ward SA. The role of S-mephenytoin hydroxylase (CYP2C19) in the metabolism of the antimalarial biguanides. Br J Clin Pharmacol 1995; 39: 441-4
    • (1995) Br J Clin Pharmacol , vol.39 , pp. 441-444
    • Wright, J.D.1    Helsby, N.A.2    Ward, S.A.3
  • 241
    • 0028228630 scopus 로고
    • In vitro proguanil activation to cycloguanil by human liver microsomes is mediated by CYP3A isoforms as well as by S-mephenytoin hydroxylase
    • Birkett DJ, Rees D, Andersson T, et al. In vitro proguanil activation to cycloguanil by human liver microsomes is mediated by CYP3A isoforms as well as by S-mephenytoin hydroxylase. Br J Clin Pharmacol 1994; 37: 413-20
    • (1994) Br J Clin Pharmacol , vol.37 , pp. 413-420
    • Birkett, D.J.1    Rees, D.2    Andersson, T.3
  • 242
    • 0025307263 scopus 로고
    • In vitro metabolism of the biguanide antimalarials in human liver microsomes: Evidence for a role of the mephenytoin hydroxylase (P450 MP) enzyme
    • Helsbey NA, Ward SA, Howells RE, et al. In vitro metabolism of the biguanide antimalarials in human liver microsomes: evidence for a role of the mephenytoin hydroxylase (P450 MP) enzyme. Br J Clin Pharmacol 1990; 30: 287-91
    • (1990) Br J Clin Pharmacol , vol.30 , pp. 287-291
    • Helsbey, N.A.1    Ward, S.A.2    Howells, R.E.3
  • 243
    • 0029960882 scopus 로고    scopus 로고
    • Chloroguanide metabolism in relation to the efficacy in malaria prophylaxis and the S-mephenytoin oxidation in Tanzanians
    • Skjelbo E, Mutabingwa TK, Bygbjerg I, et al. Chloroguanide metabolism in relation to the efficacy in malaria prophylaxis and the S-mephenytoin oxidation in Tanzanians. Clin Pharmacol Ther 1996; 59: 304-11
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 304-311
    • Skjelbo, E.1    Mutabingwa, T.K.2    Bygbjerg, I.3
  • 244
    • 0026571243 scopus 로고
    • The disposition of oral and intramuscular pyrimethamine/sulphadoxine in Kenyan children with high parasitaemia but clinically non-severe Falciparum malaria
    • Winstanley PA, Watkins WM, Newton CRJC, et al. The disposition of oral and intramuscular pyrimethamine/sulphadoxine in Kenyan children with high parasitaemia but clinically non-severe Falciparum malaria. Br J Clin Pharmacokinet 1992; 33: 143-8
    • (1992) Br J Clin Pharmacokinet , vol.33 , pp. 143-148
    • Winstanley, P.A.1    Watkins, W.M.2    Newton, C.R.J.C.3
  • 245
    • 0027232747 scopus 로고
    • Determination of isomeric N-oxide metabolites of some substituted 2,4-diaminopyrimidines by reverse-phase ion-pair high-performance liquid chromatography
    • Watkins PJ, Gorrod JW. Determination of isomeric N-oxide metabolites of some substituted 2,4-diaminopyrimidines by reverse-phase ion-pair high-performance liquid chromatography. J Chromatogr 1993; 616: 79-85
    • (1993) J Chromatogr , vol.616 , pp. 79-85
    • Watkins, P.J.1    Gorrod, J.W.2
  • 246
    • 0024506566 scopus 로고
    • Pharmacokinetics of quinacrine after intrapleural instillation in rabbits and man
    • Bjorkman S, Elisson LO, Gabrielsson J. Pharmacokinetics of quinacrine after intrapleural instillation in rabbits and man. J Pharm Pharmacol 1989; 41: 160-3
    • (1989) J Pharm Pharmacol , vol.41 , pp. 160-163
    • Bjorkman, S.1    Elisson, L.O.2    Gabrielsson, J.3
  • 247
    • 0023950223 scopus 로고
    • Inhibition of desipramine 2-hydroxylation by quinidine and quinine
    • Steiner E, Dumont E, Spina E, et al. Inhibition of desipramine 2-hydroxylation by quinidine and quinine. Clin Pharmacol Ther 1987; 43: 577-81
    • (1987) Clin Pharmacol Ther , vol.43 , pp. 577-581
    • Steiner, E.1    Dumont, E.2    Spina, E.3
  • 249
    • 0019974096 scopus 로고
    • Comparison of the disposition of total and unbound sulfisoxazole after single and multiple dosing
    • Oie S, Gambertoglio JG, Fleckenstein L. Comparison of the disposition of total and unbound sulfisoxazole after single and multiple dosing. J Pharmacokinet Biopharm 1982; 10: 157-72
    • (1982) J Pharmacokinet Biopharm , vol.10 , pp. 157-172
    • Oie, S.1    Gambertoglio, J.G.2    Fleckenstein, L.3
  • 250
    • 0028986887 scopus 로고
    • 4-Hydroxylation of sulfamethoxazole by cytochrome P450 of the cytochrome P4502C subfamily and reduction of sulfamethoxazole hydroxylamine in human and rat hepatic microsomes
    • 4-Hydroxylation of sulfamethoxazole by cytochrome P450 of the cytochrome P4502C subfamily and reduction of sulfamethoxazole hydroxylamine in human and rat hepatic microsomes. Drug Metab Dispos 1995; 23: 406-14
    • (1995) Drug Metab Dispos , vol.23 , pp. 406-414
    • Cribb, A.E.1    Spielberg, S.P.2    Griffin, G.P.3
  • 251
    • 0028872405 scopus 로고
    • Pharmacokinetics of trimethoprim-sulfamethoxazole in critically ill and non-critically ill AIDS patients
    • Chin TWF, Vanderbroucke A, Fong IW. Pharmacokinetics of trimethoprim-sulfamethoxazole in critically ill and non-critically ill AIDS patients. Antimicrob Agents Chemother 1995; 39: 28-33
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 28-33
    • Chin, T.W.F.1    Vanderbroucke, A.2    Fong, I.W.3
  • 252
    • 0019967382 scopus 로고
    • The pharmacokinetics of thiabendazole and its metabolites in an anephric patient undergoing hemodialysis and hemoperfusion
    • Bauer LA, Raisys VA, Watts MT, et al. The pharmacokinetics of thiabendazole and its metabolites in an anephric patient undergoing hemodialysis and hemoperfusion. J Clin Pharmacol 1982; 22: 276-80
    • (1982) J Clin Pharmacol , vol.22 , pp. 276-280
    • Bauer, L.A.1    Raisys, V.A.2    Watts, M.T.3
  • 253
    • 0028970173 scopus 로고
    • Trimetrexate: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the treatment of Pneumocystis carinii pneumonia
    • Fulton B, Wagstaff AJ, McTavish D. Trimetrexate: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the treatment of Pneumocystis carinii pneumonia. Drugs 1995; 49: 563-76
    • (1995) Drugs , vol.49 , pp. 563-576
    • Fulton, B.1    Wagstaff, A.J.2    McTavish, D.3
  • 254
    • 0028911385 scopus 로고
    • Clinical pharmacokinetics of nucleoside antiretroviral agents
    • Dudley MN. Clinical pharmacokinetics of nucleoside antiretroviral agents. J Infect Dis 1995; 171: S99-S112
    • (1995) J Infect Dis , vol.171
    • Dudley, M.N.1
  • 255
    • 0026721305 scopus 로고
    • Didanosine: A review of its antiviral activity, pharmacokinetic properties and therapeutic potential in human immunodeficiency virus infection
    • Faulds D, Brogden RN. Didanosine: A review of its antiviral activity, pharmacokinetic properties and therapeutic potential in human immunodeficiency virus infection. Drugs 1992; 44: 94-116
    • (1992) Drugs , vol.44 , pp. 94-116
    • Faulds, D.1    Brogden, R.N.2
  • 256
    • 0029872126 scopus 로고    scopus 로고
    • Role of cytochrome P450 3A4 in human metabolism of MK-639, a potent human immunodeficiency virus protease inhibitor
    • Chiba M, Hensleigh M, Nishime JA, et al. Role of cytochrome P450 3A4 in human metabolism of MK-639, a potent human immunodeficiency virus protease inhibitor. Drug Metab Dispos 1996; 24: 307-14
    • (1996) Drug Metab Dispos , vol.24 , pp. 307-314
    • Chiba, M.1    Hensleigh, M.2    Nishime, J.A.3
  • 257
    • 0029964107 scopus 로고    scopus 로고
    • Current knowledge and future prospects for the use of HIV protease inhibitors
    • Moyle G, Gazzard B. Current knowledge and future prospects for the use of HIV protease inhibitors. Drugs 1996; 51: 701-12
    • (1996) Drugs , vol.51 , pp. 701-712
    • Moyle, G.1    Gazzard, B.2
  • 258
    • 0029591139 scopus 로고
    • Pharmacokinetics, absolute bioavailability, and absorption characteristics of lamivudine
    • Yuen GJ, Morris DM, Mydlow PK, et al. Pharmacokinetics, absolute bioavailability, and absorption characteristics of lamivudine. J Clin Pharmacol 1995; 35: 1174-80
    • (1995) J Clin Pharmacol , vol.35 , pp. 1174-1180
    • Yuen, G.J.1    Morris, D.M.2    Mydlow, P.K.3
  • 259
    • 0028997078 scopus 로고
    • A phase I/II study of 2-deoxy-3thiacytidine (lamivudine) in patients with advanced human immunodeficiency virus infection
    • Pluda JM, Cooley TP, Montaner JSG, et al. A phase I/II study of 2-deoxy-3thiacytidine (lamivudine) in patients with advanced human immunodeficiency virus infection. J Infect Dis 1995; 171: 1438-47
    • (1995) J Infect Dis , vol.171 , pp. 1438-1447
    • Pluda, J.M.1    Cooley, T.P.2    Montaner, J.S.G.3
  • 260
    • 0030430035 scopus 로고    scopus 로고
    • Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes
    • Kumar GN, Rodrigues AD, Buko AM, et al. Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes. J Pharmacol Exp Ther 1996; 277: 423-31
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 423-431
    • Kumar, G.N.1    Rodrigues, A.D.2    Buko, A.M.3
  • 261
    • 0027321002 scopus 로고
    • In vitro and in vivo dispositon and metabolism of 3-deoxy-2,3-didehydrothymidine
    • Cretton EM, Zhou Z, Kidd LB, et al. In vitro and in vivo dispositon and metabolism of 3-deoxy-2,3-didehydrothymidine. Antimicrob Agents Chemother 1993; 37: 1816-25
    • (1993) Antimicrob Agents Chemother , vol.37 , pp. 1816-1825
    • Cretton, E.M.1    Zhou, Z.2    Kidd, L.B.3
  • 262
    • 0028939311 scopus 로고
    • Comparison of metabolism and in vitro antiviral activity of stavudine versus other 2,3-dideoxynucleoside analogues
    • Sommadossi J-P. Comparison of metabolism and in vitro antiviral activity of stavudine versus other 2,3-dideoxynucleoside analogues. J Infect Dis 1995; 171: S88-S92
    • (1995) J Infect Dis , vol.171
    • Sommadossi, J.-P.1
  • 263
    • 0029038269 scopus 로고
    • Zalcitabine: Clinical pharmacokinetics and efficacy
    • Devineni D, Gallo JM. Zalcitabine: Clinical pharmacokinetics and efficacy. Clin Pharmacokinet 1995; 28: 351-60
    • (1995) Clin Pharmacokinet , vol.28 , pp. 351-360
    • Devineni, D.1    Gallo, J.M.2
  • 265
    • 0028068832 scopus 로고
    • The metabolism of zidovudine by human liver microsomes in vitro : Formation of 3-amino-3-deoxythymidine
    • Eagling VA, Howe JL, Barry MJ, et al. The metabolism of zidovudine by human liver microsomes in vitro : formation of 3-amino-3-deoxythymidine. Biochem Pharmacol 1994; 48: 267-76
    • (1994) Biochem Pharmacol , vol.48 , pp. 267-276
    • Eagling, V.A.1    Howe, J.L.2    Barry, M.J.3
  • 266
    • 0029591968 scopus 로고
    • Metabolism of zidovudine
    • Veal GJ, Back DJ. Metabolism of zidovudine. Gen Pharmacol 1995; 26: 1469-75
    • (1995) Gen Pharmacol , vol.26 , pp. 1469-1475
    • Veal, G.J.1    Back, D.J.2
  • 267
  • 268
    • 0028799413 scopus 로고
    • Pharmacokinetics of new antiherpetic agents
    • Rolan P. Pharmacokinetics of new antiherpetic agents. Clin Pharmacokinet 1995; 29: 333-40
    • (1995) Clin Pharmacokinet , vol.29 , pp. 333-340
    • Rolan, P.1
  • 269
    • 0027480434 scopus 로고
    • Comparative pharmacokinetics of antiviral nucleoside analogues
    • Morse GD, Shelton MJ, ODonnell AM. Comparative pharmacokinetics of antiviral nucleoside analogues. Clin Pharmacokinet 1993; 24: 101-23
    • (1993) Clin Pharmacokinet , vol.24 , pp. 101-123
    • Morse, G.D.1    Shelton, M.J.2    Odonnell, A.M.3
  • 270
    • 0028936048 scopus 로고
    • (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine (cidofovir): Results of a phase I/II study of a novel antiviral nucleotide analogue
    • Lalezari JP, Drew WL, Glutzer E, et al. (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine (cidofovir): Results of a phase I/II study of a novel antiviral nucleotide analogue. J Infect Dis 1995; 171: 788-96
    • (1995) J Infect Dis , vol.171 , pp. 788-796
    • Lalezari, J.P.1    Drew, W.L.2    Glutzer, E.3
  • 271
    • 0028832926 scopus 로고
    • Role of aldehyde oxidase in the in vitro conversion of famciclovir to penciclovir in human liver
    • Clarke SE, Harrell AW, Chenery RJ. Role of aldehyde oxidase in the in vitro conversion of famciclovir to penciclovir in human liver. Drug Metab Dispos 1995; 23: 251-4
    • (1995) Drug Metab Dispos , vol.23 , pp. 251-254
    • Clarke, S.E.1    Harrell, A.W.2    Chenery, R.J.3
  • 272
    • 0028920826 scopus 로고
    • Foscarnet and ganciclovir pharmacokinetics during concomitant or alternating maintenance therapy for AIDS-related cytomegalovirus retinitis
    • Aweeka FT, Gambertoglio JG, Kramer F, et al. Foscarnet and ganciclovir pharmacokinetics during concomitant or alternating maintenance therapy for AIDS-related cytomegalovirus retinitis. Clin Pharmacol Ther 1995; 57: 403-12
    • (1995) Clin Pharmacol Ther , vol.57 , pp. 403-412
    • Aweeka, F.T.1    Gambertoglio, J.G.2    Kramer, F.3
  • 273
    • 0019160852 scopus 로고
    • Vidarabine: A preliminary review of its pharmacological properties and therapeutic use
    • Whitley R, Alford C, Hess F, et al. Vidarabine: a preliminary review of its pharmacological properties and therapeutic use. Drugs 1980; 47: 267-82
    • (1980) Drugs , vol.47 , pp. 267-282
    • Whitley, R.1    Alford, C.2    Hess, F.3
  • 274
    • 0030051034 scopus 로고    scopus 로고
    • Purification and characterization of bleomycin hydrolase, which represents a new family of cysteine proteases, from rat skin
    • Takeda A, Higuchi D, Yamamoto T, et al. Purification and characterization of bleomycin hydrolase, which represents a new family of cysteine proteases, from rat skin. J Biochem 1996; 119: 29-36
    • (1996) J Biochem , vol.119 , pp. 29-36
    • Takeda, A.1    Higuchi, D.2    Yamamoto, T.3
  • 275
    • 0020504936 scopus 로고
    • Bleomycin disposition in children with cancer
    • Yee GC, Crom WR, Lee FH, et al. Bleomycin disposition in children with cancer. Clin Pharmacol Ther 1983; 33: 668-73
    • (1983) Clin Pharmacol Ther , vol.33 , pp. 668-673
    • Yee, G.C.1    Crom, W.R.2    Lee, F.H.3
  • 276
    • 0029897684 scopus 로고    scopus 로고
    • Sensitization of human breast cancer cells to cyclophosphamide and ifosfamide by transfer of a liver cytochrome P450 gene
    • Chen L, Waxman DJ, Chen D, et al. Sensitization of human breast cancer cells to cyclophosphamide and ifosfamide by transfer of a liver cytochrome P450 gene. Cancer Res 1996; 56: 1331-40
    • (1996) Cancer Res , vol.56 , pp. 1331-1340
    • Chen, L.1    Waxman, D.J.2    Chen, D.3
  • 277
    • 0029582977 scopus 로고
    • The role of human cytochrome P450 enzymes in the metabolism of anticancer agents: Implications for drug interaction
    • Kivisto KT, Kroemer HK, Eichelbaum M. The role of human cytochrome P450 enzymes in the metabolism of anticancer agents: implications for drug interaction. Br J Clin Pharmacol 1995; 40: 523-30
    • (1995) Br J Clin Pharmacol , vol.40 , pp. 523-530
    • Kivisto, K.T.1    Kroemer, H.K.2    Eichelbaum, M.3
  • 278
    • 0029685930 scopus 로고    scopus 로고
    • Overexpression of the human aldehyde dehydrogenase class 1 results in increased resistance to 4-hydroperoxycyclophosphamide
    • Moreb J, Schweder M, Suresh A, et al. Overexpression of the human aldehyde dehydrogenase class 1 results in increased resistance to 4-hydroperoxycyclophosphamide. Cancer Gene Ther 1996; 3: 24-30
    • (1996) Cancer Gene Ther , vol.3 , pp. 24-30
    • Moreb, J.1    Schweder, M.2    Suresh, A.3
  • 279
    • 0027369366 scopus 로고
    • Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes
    • Chang TKH, Weber GF, Crespi CL, et al. Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes. Cancer Res 1993; 53: 5629-37
    • (1993) Cancer Res , vol.53 , pp. 5629-5637
    • Chang, T.K.H.1    Weber, G.F.2    Crespi, C.L.3
  • 280
    • 0020641082 scopus 로고
    • Clinical pharmacokinetics of commonly used anticancer drugs
    • Balis FM, Holcenberg JS, Bleyer WA. Clinical pharmacokinetics of commonly used anticancer drugs. Clin Pharmacokinet 1983; 8: 202-32
    • (1983) Clin Pharmacokinet , vol.8 , pp. 202-232
    • Balis, F.M.1    Holcenberg, J.S.2    Bleyer, W.A.3
  • 281
    • 0027787743 scopus 로고
    • Pharmacokinetics and metabolism of anthracyclines
    • Robert J, Gianni L. Pharmacokinetics and metabolism of anthracyclines. Cancer Surv 1993; 17: 219-51
    • (1993) Cancer Surv , vol.17 , pp. 219-251
    • Robert, J.1    Gianni, L.2
  • 282
    • 0028837002 scopus 로고
    • Expression of a 95 kDa membrane protein is associated with low daunorubicin accumulation in leukaemic blast cells
    • Doyle LA, Ross DD, Sridhara R, et al. Expression of a 95 kDa membrane protein is associated with low daunorubicin accumulation in leukaemic blast cells. Br J Cancer 1995; 71: 52-8
    • (1995) Br J Cancer , vol.71 , pp. 52-58
    • Doyle, L.A.1    Ross, D.D.2    Sridhara, R.3
  • 283
    • 0028017904 scopus 로고
    • The effects of cyclosporine on the pharmacokinetics of doxorubicin in patients with small cell lung cancer
    • Rushing DA, Raber SR, Rodvold KA, et al. The effects of cyclosporine on the pharmacokinetics of doxorubicin in patients with small cell lung cancer. Cancer 1994; 74: 834-41
    • (1994) Cancer , vol.74 , pp. 834-841
    • Rushing, D.A.1    Raber, S.R.2    Rodvold, K.A.3
  • 284
    • 0028009274 scopus 로고
    • O-Demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4
    • Relling MV, Nemec J, Schuetz EG, et al. O-Demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4. Mol Pharmacol 1994; 45: 352-8
    • (1994) Mol Pharmacol , vol.45 , pp. 352-358
    • Relling, M.V.1    Nemec, J.2    Schuetz, E.G.3
  • 285
    • 0023235581 scopus 로고
    • The clinical pharmacology of etoposide and teniposide
    • Clark PI, Slevin ML. The clinical pharmacology of etoposide and teniposide. Clin Pharmacokinet 1987; 12: 223-52
    • (1987) Clin Pharmacokinet , vol.12 , pp. 223-252
    • Clark, P.I.1    Slevin, M.L.2
  • 286
    • 0024595925 scopus 로고
    • Clinical pharmacology of 5-fluorouracil
    • Diasio RB, Harris BE. Clinical pharmacology of 5-fluorouracil. Clin Pharmacokinet 1989; 16: 215-37
    • (1989) Clin Pharmacokinet , vol.16 , pp. 215-237
    • Diasio, R.B.1    Harris, B.E.2
  • 287
    • 0029923839 scopus 로고    scopus 로고
    • Pharmacokinetics of hydroxyurca in patients infected with human immunodeficiency virus type I
    • Villani P, Maserati R, Regazzi MB, et al. Pharmacokinetics of hydroxyurca in patients infected with human immunodeficiency virus type I. J Clin Pharmacol 1996; 36: 117-21
    • (1996) J Clin Pharmacol , vol.36 , pp. 117-121
    • Villani, P.1    Maserati, R.2    Regazzi, M.B.3
  • 288
    • 0028985925 scopus 로고
    • The kinetics of the auto-induction of ifosfamide metabolism during continuous infusion
    • Boddy AV, Cole M, Pearson ADJ, et al. The kinetics of the auto-induction of ifosfamide metabolism during continuous infusion. Cancer Chemother Pharmacol 1995; 36: 53-60
    • (1995) Cancer Chemother Pharmacol , vol.36 , pp. 53-60
    • Boddy, A.V.1    Cole, M.2    Pearson, A.D.J.3
  • 289
    • 0026354562 scopus 로고
    • Metabolism and pharmacokinetics of oral and intravenous ifosfamide
    • Kurowski V, Cerny T, Kupfer A, et al. Metabolism and pharmacokinetics of oral and intravenous ifosfamide. J Cancer Res Clin Oncol 1991; 117: S148-S153
    • (1991) J Cancer Res Clin Oncol , vol.117
    • Kurowski, V.1    Cerny, T.2    Kupfer, A.3
  • 290
    • 0025203837 scopus 로고
    • Clinical pharmcokinetics of interferons
    • Wills RJ. Clinical pharmcokinetics of interferons. Clin Pharmacokinet 1990; 19: 390-9
    • (1990) Clin Pharmacokinet , vol.19 , pp. 390-399
    • Wills, R.J.1
  • 291
    • 0027179010 scopus 로고
    • Effects of interferon-α monotherapy on hepatic drug metabolism in cancer patients
    • Israel BC, Blouin RA, McIntyre W, et al. Effects of interferon-α monotherapy on hepatic drug metabolism in cancer patients. Br J Clin Pharmacol 1993; 36: 229-35
    • (1993) Br J Clin Pharmacol , vol.36 , pp. 229-235
    • Israel, B.C.1    Blouin, R.A.2    McIntyre, W.3
  • 292
    • 0029898079 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of low-dose pulse methotrexate in rheumatoid arthritis
    • Bannwarth B, Péhourcq F, Schaeverbeke T, et al. Clinical pharmacokinetics of low-dose pulse methotrexate in rheumatoid arthritis. Clin Pharmacokinet 1996; 30: 194-210
    • (1996) Clin Pharmacokinet , vol.30 , pp. 194-210
    • Bannwarth, B.1    Péhourcq, F.2    Schaeverbeke, T.3
  • 294
    • 0029003696 scopus 로고
    • Metabolism of îaxol by human and rat liver in vitro: A screen for drug interactions and interspecies differences
    • Jamis-Dow CA, Klecker RW, Katki AG, et al. Metabolism of îaxol by human and rat liver in vitro: A screen for drug interactions and interspecies differences. Cancer Chemother Pharmacol 1995; 35: 107-14
    • (1995) Cancer Chemother Pharmacol , vol.35 , pp. 107-114
    • Jamis-Dow, C.A.1    Klecker, R.W.2    Katki, A.G.3
  • 295
    • 0029061742 scopus 로고
    • Comparative in vitro cytotoxic effects of taxol and its major human metabolite 6α-hydroxytaxol
    • Kumar G, Ray S, Walle T, et al. Comparative in vitro cytotoxic effects of taxol and its major human metabolite 6α-hydroxytaxol. Cancer Chemother Pharmacol 1995; 36: 129-35
    • (1995) Cancer Chemother Pharmacol , vol.36 , pp. 129-135
    • Kumar, G.1    Ray, S.2    Walle, T.3
  • 296
    • 0029584558 scopus 로고
    • Variability in human cytochrome P450 paclitaxel metabolism
    • Sonnichsen DS, Liu Q, Schuctz EG, et al. Variability in human cytochrome P450 paclitaxel metabolism. J Pharmacol Exp Ther 1995; 275: 566-75
    • (1995) J Pharmacol Exp Ther , vol.275 , pp. 566-575
    • Sonnichsen, D.S.1    Liu, Q.2    Schuctz, E.G.3
  • 297
    • 0028670421 scopus 로고
    • Involvement of cytochrome P4503A in catalysis of tamoxifen activation and covalent binding to rat and human liver microsomes
    • Mani C, Pearce R, Parkinson A, et al. Involvement of cytochrome P4503A in catalysis of tamoxifen activation and covalent binding to rat and human liver microsomes. Carcinogenesis 1994; 15: 2715-20
    • (1994) Carcinogenesis , vol.15 , pp. 2715-2720
    • Mani, C.1    Pearce, R.2    Parkinson, A.3
  • 298
  • 299
    • 0028596462 scopus 로고
    • Interindividual variation in the isomerization of 4-hydroxytamoxifen by human liver microsomes: Involvement of cytochromes P450
    • Williams ML, Lennard MS, Martin IJ, et al. Interindividual variation in the isomerization of 4-hydroxytamoxifen by human liver microsomes: involvement of cytochromes P450. Carcinogenesis 1994; 15: 2733-8
    • (1994) Carcinogenesis , vol.15 , pp. 2733-2738
    • Williams, M.L.1    Lennard, M.S.2    Martin, I.J.3
  • 300
    • 0027443019 scopus 로고
    • Involvement of human liver cytochrome P450 3A in vinblastine metabolism: Drug interactions
    • Zhou-Pan X-R, Sérée E, Zhou X-J, et al. Involvement of human liver cytochrome P450 3A in vinblastine metabolism: drug interactions. Cancer Res 1993; 53: 5121-6
    • (1993) Cancer Res , vol.53 , pp. 5121-5126
    • Zhou-Pan, X.-R.1    Sérée, E.2    Zhou, X.-J.3
  • 301
    • 0027787742 scopus 로고
    • Pharmacokinetics and metabolism of Vinca alkaloids
    • Rahmani R, Zhou X-J. Pharmacokinetics and metabolism of Vinca alkaloids. Cancer Surv 1993; 17: 269-81
    • (1993) Cancer Surv , vol.17 , pp. 269-281
    • Rahmani, R.1    Zhou, X.-J.2
  • 302
    • 0025146303 scopus 로고
    • Clinical pharmacokinetics of the newer ACE inhibitors. A review
    • Kelley JG, OMalley K. Clinical pharmacokinetics of the newer ACE inhibitors. A review. Clin Pharmacokinet 1990; 19: 177-96
    • (1990) Clin Pharmacokinet , vol.19 , pp. 177-196
    • Kelley, J.G.1    Omalley, K.2
  • 303
    • 0023899603 scopus 로고
    • Pharmacokinetics of captopril in healthy subjects and in patients with cardiovascular diseases
    • Duchin KL, McKinstry DN, Cohen AI, et al. Pharmacokinetics of captopril in healthy subjects and in patients with cardiovascular diseases. Clin Pharmacokinet 1988; 14: 241-59
    • (1988) Clin Pharmacokinet , vol.14 , pp. 241-259
    • Duchin, K.L.1    McKinstry, D.N.2    Cohen, A.I.3
  • 304
    • 0027437840 scopus 로고
    • Enalapril clinical pharmacokinetics and pharmacokinetic-pharmacodynamic relationships
    • MacFadyen RJ, Meredith PA, Elliott HL. Enalapril clinical pharmacokinetics and pharmacokinetic-pharmacodynamic relationships. Clin Pharmacokinet 1993; 25: 274-82
    • (1993) Clin Pharmacokinet , vol.25 , pp. 274-282
    • MacFadyen, R.J.1    Meredith, P.A.2    Elliott, H.L.3
  • 305
    • 0028835364 scopus 로고
    • Single-dose and steady-state pharmacokinetics of fosinopril and fosinoprilat in patients with hepatic impairment
    • Ford NF, Lasseter KC, Van Harken DR, et al. Single-dose and steady-state pharmacokinetics of fosinopril and fosinoprilat in patients with hepatic impairment. J Clin Pharmacol 1995; 35: 145-50
    • (1995) J Clin Pharmacol , vol.35 , pp. 145-150
    • Ford, N.F.1    Lasseter, K.C.2    Van Harken, D.R.3
  • 306
    • 0027379673 scopus 로고
    • Evidence for CYP3A-mediated N-deethylation of amiodarone in human liver microsomal fractions
    • Fahre G, Julian B, Saint-Aubert B, et al. Evidence for CYP3A-mediated N-deethylation of amiodarone in human liver microsomal fractions. Drug Metab Dispos 1995; 21: 978-85
    • (1995) Drug Metab Dispos , vol.21 , pp. 978-985
    • Fahre, G.1    Julian, B.2    Saint-Aubert, B.3
  • 307
    • 0026604734 scopus 로고
    • Amiodarone: An overview of its pharmacological properties and review of its therapeutic use in cardiac arrhythmias
    • Gill J, Heel RC, Fitton A. Amiodarone: an overview of its pharmacological properties and review of its therapeutic use in cardiac arrhythmias. Drugs 1992; 43: 69-110
    • (1992) Drugs , vol.43 , pp. 69-110
    • Gill, J.1    Heel, R.C.2    Fitton, A.3
  • 308
    • 0027455141 scopus 로고
    • The mechanism of the verapamil-digoxin interaction in renal tubular cells (LLC-PKI)
    • Ito S, Woodland C, Harper PA, et al. The mechanism of the verapamil-digoxin interaction in renal tubular cells (LLC-PKI). Life Sci 1993; 53: PL399-PL403
    • (1993) Life Sci , vol.53
    • Ito, S.1    Woodland, C.2    Harper, P.A.3
  • 309
    • 0023772455 scopus 로고
    • Digitalis: An update of clinical pharmacokinetics, therapeutic monmitoring techniques, and treatment recommendations
    • Mooradian AD. Digitalis: an update of clinical pharmacokinetics, therapeutic monmitoring techniques, and treatment recommendations. Clin Pharmacokinet 1988; 15: 165-79
    • (1988) Clin Pharmacokinet , vol.15 , pp. 165-179
    • Mooradian, A.D.1
  • 310
  • 311
    • 0027440310 scopus 로고
    • A potent inhibitory effect of erythromycin and other macrolide antibiotics on the mono-N-dealkylation metabolism of disopyramide with human liver microsomes
    • Echizen H, Kawasaki H, China K, et al. A potent inhibitory effect of erythromycin and other macrolide antibiotics on the mono-N-dealkylation metabolism of disopyramide with human liver microsomes. J Pharmacol Exp Ther 1993; 264: 1425-31
    • (1993) J Pharmacol Exp Ther , vol.264 , pp. 1425-1431
    • Echizen, H.1    Kawasaki, H.2    China, K.3
  • 312
    • 0021347053 scopus 로고
    • Influence of genetic polymorphism on the metabolism and disposition of encainide in man
    • Wang T, Wolfenden HT, Woosley RL, et al. Influence of genetic polymorphism on the metabolism and disposition of encainide in man. J Pharmacol Exp Ther 1984; 228: 605-11
    • (1984) J Pharmacol Exp Ther , vol.228 , pp. 605-611
    • Wang, T.1    Wolfenden, H.T.2    Woosley, R.L.3
  • 313
    • 0026472355 scopus 로고
    • Polymorphism of dextromethorphan metabolism: Relationships between phenotype, genotype and response to the administration of encainide in humans
    • Funck-Bretano C, Thomas G, Jacqz-Aigrain E, et al. Polymorphism of dextromethorphan metabolism: relationships between phenotype, genotype and response to the administration of encainide in humans. J Pharmacol Exp Ther 1992; 263: 780-5
    • (1992) J Pharmacol Exp Ther , vol.263 , pp. 780-785
    • Funck-Bretano, C.1    Thomas, G.2    Jacqz-Aigrain, E.3
  • 314
    • 0023724194 scopus 로고
    • Is there a genetic factor in flecainide toxicity?
    • Beckmann J, Hertrampf R, Gundert-Remy U, et al. Is there a genetic factor in flecainide toxicity? BMJ 1988; 297: 1316
    • (1988) BMJ , vol.297 , pp. 1316
    • Beckmann, J.1    Hertrampf, R.2    Gundert-Remy, U.3
  • 315
    • 0028236315 scopus 로고
    • Variable disposition kinetics and electrocardiographic effects of flecainide during repeated dosing in humans: Contribution of genetic factors, dose-dependent clearance, and interaction with amiodarone
    • Funck-Brentano C, Becquemont L, Kroemer HK, et al. Variable disposition kinetics and electrocardiographic effects of flecainide during repeated dosing in humans: contribution of genetic factors, dose-dependent clearance, and interaction with amiodarone. Clin Pharmacol Ther 1994; 55: 256-69
    • (1994) Clin Pharmacol Ther , vol.55 , pp. 256-269
    • Funck-Brentano, C.1    Becquemont, L.2    Kroemer, H.K.3
  • 316
    • 0025601454 scopus 로고
    • Lidocaine metabolism by human cytochrome P-450s purified from hepatic microsomes: Comparison of those with rat hepatic cytochrome P-450s
    • Iamoko S, Enomoto K, Oda Y, et al. Lidocaine metabolism by human cytochrome P-450s purified from hepatic microsomes: comparison of those with rat hepatic cytochrome P-450s. J Pharmacol Exp Ther 1990; 255: 1385-91
    • (1990) J Pharmacol Exp Ther , vol.255 , pp. 1385-1391
    • Iamoko, S.1    Enomoto, K.2    Oda, Y.3
  • 317
    • 0023226617 scopus 로고
    • The pharmacokinetics of lignocaine and β-adrenoceptor antagonists in patients with acute myocardial infarction
    • Nattel S, Gagne G, Pineau M. The pharmacokinetics of lignocaine and β-adrenoceptor antagonists in patients with acute myocardial infarction. Clin Pharmacokinet 1987; 13: 293-316
    • (1987) Clin Pharmacokinet , vol.13 , pp. 293-316
    • Nattel, S.1    Gagne, G.2    Pineau, M.3
  • 318
    • 0026342550 scopus 로고
    • Influence of debrisoquin phenotype and of quinidine on mexiletine disposition in man
    • Turgeon J, Fiset C, Giguère R, et al. Influence of debrisoquin phenotype and of quinidine on mexiletine disposition in man. J Pharmacol Exp Ther 1991; 259: 789-98
    • (1991) J Pharmacol Exp Ther , vol.259 , pp. 789-798
    • Turgeon, J.1    Fiset, C.2    Giguère, R.3
  • 319
    • 0018427570 scopus 로고
    • Clinical pharmacokinetics of procainamide infusions in relation to acetylator phenotype
    • Lima JJ, Conti DR, Goldfarb AL. Clinical pharmacokinetics of procainamide infusions in relation to acetylator phenotype. J Pharmacokinet Biopharm 1979; 7: 69-85
    • (1979) J Pharmacokinet Biopharm , vol.7 , pp. 69-85
    • Lima, J.J.1    Conti, D.R.2    Goldfarb, A.L.3
  • 320
    • 0024455874 scopus 로고
    • Pharmacokinetics of N-acetylprocainamide in patients profiled with a stable isotope method
    • Atkinson AJ Jr, Ruo TI, Piergies AA, et al. Pharmacokinetics of N-acetylprocainamide in patients profiled with a stable isotope method. Clin Pharmacol Ther 1989; 46
    • (1989) Clin Pharmacol Ther , vol.46
    • Atkinson Jr., A.J.1    Ruo, T.I.2    Piergies, A.A.3
  • 321
    • 0025823440 scopus 로고
    • Enantiomer/enantiomer interaction of (S)- And (R)-propafenone for cytochrome P450IID6-catalyzed 5-hydroxylation: In vitro evaluation of the mechanism
    • Kroemer HK, Fischer C, Meese CO, et al. Enantiomer/enantiomer interaction of (S)- and (R)-propafenone for cytochrome P450IID6-catalyzed 5-hydroxylation: In vitro evaluation of the mechanism. Mol Pharmacol 1991; 40: 135-42
    • (1991) Mol Pharmacol , vol.40 , pp. 135-142
    • Kroemer, H.K.1    Fischer, C.2    Meese, C.O.3
  • 322
    • 0028824253 scopus 로고
    • Propafenone in a usual dose produces severe side-effects: The impact of genetically determined metabolic status on drug therapy
    • Mörike K, Magadum S, Mettang T, et al. Propafenone in a usual dose produces severe side-effects: The impact of genetically determined metabolic status on drug therapy. J Intern Med 1995; 238: 469-72
    • (1995) J Intern Med , vol.238 , pp. 469-472
    • Mörike, K.1    Magadum, S.2    Mettang, T.3
  • 323
    • 0024548251 scopus 로고
    • In vitro characterisation of the human cytochrome P-450 involved in polymorphic oxidation of propafenone
    • Kroemer HK, Mikus G, Kronbach T, et al. In vitro characterisation of the human cytochrome P-450 involved in polymorphic oxidation of propafenone. Clin Pharmacol Ther 1989; 45: 28-33
    • (1989) Clin Pharmacol Ther , vol.45 , pp. 28-33
    • Kroemer, H.K.1    Mikus, G.2    Kronbach, T.3
  • 324
    • 0023122069 scopus 로고
    • Polymorphism of propafenone metabolism and disposition in man: Clinical and pharmacokinetic consequences
    • Siddoway LA, Thompson KA, McAllister CB, et al. Polymorphism of propafenone metabolism and disposition in man: Clinical and pharmacokinetic consequences. Circulation 1987; 75: 785-91
    • (1987) Circulation , vol.75 , pp. 785-791
    • Siddoway, L.A.1    Thompson, K.A.2    McAllister, C.B.3
  • 325
    • 0028876653 scopus 로고
    • Possible inhibition of hepatic metabolism of quinidine by erytnromycin
    • Spinier SS, Cheng JWM, Kindwall KE, et al. Possible inhibition of hepatic metabolism of quinidine by erytnromycin. Clin Pharmacol Ther 1995; 57: 89-94
    • (1995) Clin Pharmacol Ther , vol.57 , pp. 89-94
    • Spinier, S.S.1    Cheng, J.W.M.2    Kindwall, K.E.3
  • 326
    • 0029050135 scopus 로고
    • Potent inhibition of yeast-expressed CYP2D6 by dihydroquinidine, quinidine and its metabolites
    • Ching MS, Blake CL, Ghabrial H, et al. Potent inhibition of yeast-expressed CYP2D6 by dihydroquinidine, quinidine and its metabolites. Biochem Pharmacol 1995; 50: 833-7
    • (1995) Biochem Pharmacol , vol.50 , pp. 833-837
    • Ching, M.S.1    Blake, C.L.2    Ghabrial, H.3
  • 328
    • 0026525121 scopus 로고
    • Pharmacokinetics of quinidine in male patients: A population analysis
    • Verme CN, Ludden TM, Clementi WA, et al. Pharmacokinetics of quinidine in male patients: A population analysis. Clin Pharmacokinet 1992; 22: 468-80
    • (1992) Clin Pharmacokinet , vol.22 , pp. 468-480
    • Verme, C.N.1    Ludden, T.M.2    Clementi, W.A.3
  • 329
    • 0029087821 scopus 로고
    • Pharmacokinetic interactions of nifedipine and quinidine
    • Hippius M, Henschel L, Sigusch H, et al. Pharmacokinetic interactions of nifedipine and quinidine. Pharmazie 1995; 50: 613-6
    • (1995) Pharmazie , vol.50 , pp. 613-616
    • Hippius, M.1    Henschel, L.2    Sigusch, H.3
  • 330
    • 0022998722 scopus 로고
    • Sparteine oxidation is practically abolished in quinidine-treated patients
    • Brinn R, Brøsen K, Gram LF, et al. Sparteine oxidation is practically abolished in quinidine-treated patients. Br J Clin Pharmacol 1986; 22: 194-7
    • (1986) Br J Clin Pharmacol , vol.22 , pp. 194-197
    • Brinn, R.1    Brøsen, K.2    Gram, L.F.3
  • 332
    • 0019143383 scopus 로고
    • Clinical pharmacokinetics of heparin
    • Estes JW. Clinical pharmacokinetics of heparin. Clin Pharmacokinet 1980; 5: 204-20
    • (1980) Clin Pharmacokinet , vol.5 , pp. 204-220
    • Estes, J.W.1
  • 333
    • 0026576324 scopus 로고
    • Heparin pharmacokinetics and pharmacodynamics
    • Kandrotas RJ. Heparin pharmacokinetics and pharmacodynamics. Clin Pharmacokinet 1992; 22: 359-74
    • (1992) Clin Pharmacokinet , vol.22 , pp. 359-374
    • Kandrotas, R.J.1
  • 335
    • 0027267722 scopus 로고
    • Human liver microsomal metabolism of the enantiomers of warfarin and acenocoumaral: P450 isozyme diversity determines the differences in their pharrnacokinetics
    • Hermans JJR, Thijssen HHW. Human liver microsomal metabolism of the enantiomers of warfarin and acenocoumaral: P450 isozyme diversity determines the differences in their pharrnacokinetics. Br J Pharmacol 1993; 110: 482-90
    • (1993) Br J Pharmacol , vol.110 , pp. 482-490
    • Hermans, J.J.R.1    Thijssen, H.H.W.2
  • 336
    • 0029037096 scopus 로고
    • Inhibition of (S)-warfarin metabolism by sulfinpyrazone and its metabolites
    • He M, Kunze KL, Trager WF. Inhibition of (S)-warfarin metabolism by sulfinpyrazone and its metabolites. Drug Metab Dispos 1995; 23: 659-63
    • (1995) Drug Metab Dispos , vol.23 , pp. 659-663
    • He, M.1    Kunze, K.L.2    Trager, W.F.3
  • 337
    • 0029559028 scopus 로고
    • Human cytochromes P4501A1 and P4501A2: R-warfarin metabolism as a probe
    • Zhang Z, Fasco MJ, Huang Z, et al. Human cytochromes P4501A1 and P4501A2: R-warfarin metabolism as a probe. Drug Metab Dispos 1995; 23: 1339-45
    • (1995) Drug Metab Dispos , vol.23 , pp. 1339-1345
    • Zhang, Z.1    Fasco, M.J.2    Huang, Z.3
  • 338
    • 0029867317 scopus 로고    scopus 로고
    • Formation of (R)-8-hydroxywarfarin in human liver microsomes
    • Wienkers LC, Wurden CJ, Storch E, et al. Formation of (R)-8-hydroxywarfarin in human liver microsomes. Drug Metab Dispos 1996; 24: 610-4
    • (1996) Drug Metab Dispos , vol.24 , pp. 610-614
    • Wienkers, L.C.1    Wurden, C.J.2    Storch, E.3
  • 339
    • 0029041921 scopus 로고
    • Pharmacokinetic and pharmacodynamic evaluation of warfarin and nefazodone coadministration in healthy subjects
    • Salazar DE, Dockens RC, Milbrath RL, et al. Pharmacokinetic and pharmacodynamic evaluation of warfarin and nefazodone coadministration in healthy subjects. J Clin Pharmacol 1995; 35: 730-8
    • (1995) J Clin Pharmacol , vol.35 , pp. 730-738
    • Salazar, D.E.1    Dockens, R.C.2    Milbrath, R.L.3
  • 340
    • 0022611656 scopus 로고
    • Acebutolol: A review of its pharmacology, pharmacokinetics, clinical uses, and adverse effects
    • Singh BN, Thoden WR, Wahl J. Acebutolol: a review of its pharmacology, pharmacokinetics, clinical uses, and adverse effects. Pharmacotherapy 1986; 6: 45-63
    • (1986) Pharmacotherapy , vol.6 , pp. 45-63
    • Singh, B.N.1    Thoden, W.R.2    Wahl, J.3
  • 341
    • 0025990589 scopus 로고
    • Metabolites of antihypertensive drugs. An updated review of their clinical pharmacokinetic and therapeutic implications
    • Ebihara A, Fujimura A. Metabolites of antihypertensive drugs. An updated review of their clinical pharmacokinetic and therapeutic implications. Clin Pharmacokinet 1991; 21: 331-43
    • (1991) Clin Pharmacokinet , vol.21 , pp. 331-343
    • Ebihara, A.1    Fujimura, A.2
  • 342
    • 0022182790 scopus 로고
    • Timolol and atenolol: Relationships between oxidation phenotype, pharmacokinetics and pharmacodynamics
    • Lewis RV, Lennard MS, Jackson PR, et al. Timolol and atenolol: relationships between oxidation phenotype, pharmacokinetics and pharmacodynamics. Br J Clin Pharmacol 1985; 19: 329-33
    • (1985) Br J Clin Pharmacol , vol.19 , pp. 329-333
    • Lewis, R.V.1    Lennard, M.S.2    Jackson, P.R.3
  • 343
    • 0022470627 scopus 로고
    • Debrisoquine polymorphism and the metabolism and action of metoprolol, timolol, propranolol and atenolol
    • Lennard MS, Tucker GT, Silas JH, et al. Debrisoquine polymorphism and the metabolism and action of metoprolol, timolol, propranolol and atenolol. Xenobiotica 1986; 16: 435-77
    • (1986) Xenobiotica , vol.16 , pp. 435-477
    • Lennard, M.S.1    Tucker, G.T.2    Silas, J.H.3
  • 346
    • 0023547394 scopus 로고
    • The effect of impaired renal function on the multiple dose clinical pharmacokinetics of carteolol
    • Sennello LT, Finley RA, Chu S-Y, et al. The effect of impaired renal function on the multiple dose clinical pharmacokinetics of carteolol. Adv Ther 1987; 4: 298-308
    • (1987) Adv Ther , vol.4 , pp. 298-308
    • Sennello, L.T.1    Finley, R.A.2    Chu, S.-Y.3
  • 347
    • 0025772279 scopus 로고
    • Clinical pharmacokinetics and kinetic-dynamic relationships of delevalol and labetalol
    • Donnelly R, Macphee GJA. Clinical pharmacokinetics and kinetic-dynamic relationships of delevalol and labetalol. Clin Pharmacokinet 1991; 21: 95-109
    • (1991) Clin Pharmacokinet , vol.21 , pp. 95-109
    • Donnelly, R.1    Macphee, G.J.A.2
  • 348
    • 0028906331 scopus 로고
    • Regioselective and stereoselective oxidation of metoprolol and bufuralol catalyzed by microsomes containing cDNA-expressed human P4502D6
    • Mautz D, Nelson WL, Shen DD. Regioselective and stereoselective oxidation of metoprolol and bufuralol catalyzed by microsomes containing cDNA-expressed human P4502D6. Drug Metab Dispos 1995; 23: 513-7
    • (1995) Drug Metab Dispos , vol.23 , pp. 513-517
    • Mautz, D.1    Nelson, W.L.2    Shen, D.D.3
  • 349
    • 0029919063 scopus 로고    scopus 로고
    • Metoprolol metabolism via cytochrome P4502D6 in ethnic populations
    • Johnson JA, Burlew BS. Metoprolol metabolism via cytochrome P4502D6 in ethnic populations. Drug Metab Dispos 1996; 24: 350-5
    • (1996) Drug Metab Dispos , vol.24 , pp. 350-355
    • Johnson, J.A.1    Burlew, B.S.2
  • 350
    • 0022620540 scopus 로고
    • Single-dose quinidine treatment inhibits metoprolol oxidation in extensive metabolisers
    • Leemann TP, Dayer P, Meyer UA. Single-dose quinidine treatment inhibits metoprolol oxidation in extensive metabolisers. Eur J Clin Pharmacol 1986; 29: 739-41
    • (1986) Eur J Clin Pharmacol , vol.29 , pp. 739-741
    • Leemann, T.P.1    Dayer, P.2    Meyer, U.A.3
  • 351
    • 0021082394 scopus 로고
    • Differential stereoselective metabolism of metoprolol in extensive and poor debrisoquin metabolizers
    • Lennard MS, Tucker GT, Silas JH, et al. Differential stereoselective metabolism of metoprolol in extensive and poor debrisoquin metabolizers. Clin Pharmacol Ther 1983; 34: 732-7
    • (1983) Clin Pharmacol Ther , vol.34 , pp. 732-737
    • Lennard, M.S.1    Tucker, G.T.2    Silas, J.H.3
  • 352
    • 0022381040 scopus 로고
    • Metoprolol metabolism and debrisoquine oxidation polymorphism: Population and family studies
    • McGourty JC, Silas JH, Lennard MS, et al. Metoprolol metabolism and debrisoquine oxidation polymorphism: population and family studies. Br J Clin Pharmacol 1985; 20: 555-66
    • (1985) Br J Clin Pharmacol , vol.20 , pp. 555-566
    • McGourty, J.C.1    Silas, J.H.2    Lennard, M.S.3
  • 353
    • 0020409410 scopus 로고
    • Oxidation phenotype. a major determinant of metoprolol metabolism and response
    • Lennard MS, Silas JH, Freestone S, et al. Oxidation phenotype. a major determinant of metoprolol metabolism and response. N Engl J Med 1982; 307: 1558-60
    • (1982) N Engl J Med , vol.307 , pp. 1558-1560
    • Lennard, M.S.1    Silas, J.H.2    Freestone, S.3
  • 354
    • 0023833916 scopus 로고
    • Dose proportionality of nadolol pharmacokineties after intravenous administration to healthy subjects
    • Morrison RA, Singhvi SM, Creasey WA, et al. Dose proportionality of nadolol pharmacokineties after intravenous administration to healthy subjects. Eur J Clin Pharmacol 1988; 33: 625-8
    • (1988) Eur J Clin Pharmacol , vol.33 , pp. 625-628
    • Morrison, R.A.1    Singhvi, S.M.2    Creasey, W.A.3
  • 355
    • 0022637069 scopus 로고
    • The polymorphic oxidation of beta-adrenoceptor antagonists: Clinical pharmacokinetic considerations
    • Lennard MS, Tucker GT, Woods HF. The polymorphic oxidation of beta-adrenoceptor antagonists: clinical pharmacokinetic considerations. Clin Pharmacokinet 1986; 11: 1-17
    • (1986) Clin Pharmacokinet , vol.11 , pp. 1-17
    • Lennard, M.S.1    Tucker, G.T.2    Woods, H.F.3
  • 356
    • 0025734765 scopus 로고
    • Pharmacokinetic optimisation of therapy with beta-adrenergic blocking agents
    • Frishman WH, Lazar EJ, Gorodokin G. Pharmacokinetic optimisation of therapy with beta-adrenergic blocking agents. Clin Pharmacokinet 1991; 20: 311-8
    • (1991) Clin Pharmacokinet , vol.20 , pp. 311-318
    • Frishman, W.H.1    Lazar, E.J.2    Gorodokin, G.3
  • 357
    • 0021345446 scopus 로고
    • Competitive inhibition of sparteine oxidation in human liver by beta-adrenoceptor antagonists and other cardiovascular drugs
    • Otton SV, Inaba T, Kalow W. Competitive inhibition of sparteine oxidation in human liver by beta-adrenoceptor antagonists and other cardiovascular drugs. Life Sci 1984; 34: 73-80
    • (1984) Life Sci , vol.34 , pp. 73-80
    • Otton, S.V.1    Inaba, T.2    Kalow, W.3
  • 358
    • 0020521466 scopus 로고
    • Estimation of the absolute oral bioavailability of pindolol by two analytical methods
    • Guerret M, Cheymol G, Aubry JP, et al. Estimation of the absolute oral bioavailability of pindolol by two analytical methods. Eur J Clin Pharmacol 1983; 25: 357-9
    • (1983) Eur J Clin Pharmacol , vol.25 , pp. 357-359
    • Guerret, M.1    Cheymol, G.2    Aubry, J.P.3
  • 359
    • 0021179556 scopus 로고
    • The relationship between debrisoquine oxidation phenotype and the pharmacokinetics and pharmacodynamics of propranolol
    • Lennard MS, Jackson PR, Freestone S, et al. The relationship between debrisoquine oxidation phenotype and the pharmacokinetics and pharmacodynamics of propranolol. Br J Clin Pharmacol 1984; 39: 679-85
    • (1984) Br J Clin Pharmacol , vol.39 , pp. 679-685
    • Lennard, M.S.1    Jackson, P.R.2    Freestone, S.3
  • 361
    • 0028956887 scopus 로고
    • Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers: N-desisopropylation is mediated mainly by CYP1A2
    • Yoshimoto K, Echizen H, Chiba K, et al. Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers: N-desisopropylation is mediated mainly by CYP1A2. Br J Clin Pharmacol 1995; 39: 421-31
    • (1995) Br J Clin Pharmacol , vol.39 , pp. 421-431
    • Yoshimoto, K.1    Echizen, H.2    Chiba, K.3
  • 362
    • 0030028540 scopus 로고    scopus 로고
    • Propranolol 4- And 5-hydroxylation and N-desisopropylation by cloned human cytochrome P4501A1 and P4501A2
    • Ching MS, Bichara N, Blake CL, et al. Propranolol 4- and 5-hydroxylation and N-desisopropylation by cloned human cytochrome P4501A1 and P4501A2. Drug Metab Dispos 1996; 24: 692-4
    • (1996) Drug Metab Dispos , vol.24 , pp. 692-694
    • Ching, M.S.1    Bichara, N.2    Blake, C.L.3
  • 363
    • 0024534047 scopus 로고
    • Propranolols metabolism is determined by both mephenytoin and debrisoquin hydroxylase activities
    • Ward SA, Walle T, Walle K, et al. Propranolols metabolism is determined by both mephenytoin and debrisoquin hydroxylase activities. Clin Pharmacol Ther 1989; 45: 72-9
    • (1989) Clin Pharmacol Ther , vol.45 , pp. 72-79
    • Ward, S.A.1    Walle, T.2    Walle, K.3
  • 364
    • 0025138732 scopus 로고
    • Pharmacology, pharmacodynamics and pharmacokinetics of sotalol
    • Antonaccio MJ, Gomoll A. Pharmacology, pharmacodynamics and pharmacokinetics of sotalol. Am J Cardiol 1990; 65: 12A-21A
    • (1990) Am J Cardiol , vol.65
    • Antonaccio, M.J.1    Gomoll, A.2
  • 365
    • 0029049389 scopus 로고
    • Amlodipine. A reappraisal of its pharmacological properties and therapeutic use in cardiovascular disease
    • Haria M, Wagstaff AJ. Amlodipine. A reappraisal of its pharmacological properties and therapeutic use in cardiovascular disease. Drugs 1995; 50: 560-86
    • (1995) Drugs , vol.50 , pp. 560-586
    • Haria, M.1    Wagstaff, A.J.2
  • 366
    • 0028911110 scopus 로고
    • Pharmacokinetics of bepridil and two of its metabolites in patients with end-stage renal disease
    • Awni WM, Halstenson CE, Nayak RK, et al. Pharmacokinetics of bepridil and two of its metabolites in patients with end-stage renal disease. J Clin Pharmacol 1995; 35: 379-83
    • (1995) J Clin Pharmacol , vol.35 , pp. 379-383
    • Awni, W.M.1    Halstenson, C.E.2    Nayak, R.K.3
  • 367
    • 0025168996 scopus 로고
    • Identification of the rabbit and human cytochromes P-450IIIA as the major enzymes involved in the N-demethylation of diltiazem
    • Pichard L, Gillet G, Fabre I, et al. Identification of the rabbit and human cytochromes P-450IIIA as the major enzymes involved in the N-demethylation of diltiazem. Drug Metab Dispos 1990; 18: 711-9
    • (1990) Drug Metab Dispos , vol.18 , pp. 711-719
    • Pichard, L.1    Gillet, G.2    Fabre, I.3
  • 368
    • 0029584276 scopus 로고
    • Substrates of human hepatic cytochrome P450 3A4
    • Li AP, Kaminski DL, Rasmussen A. Substrates of human hepatic cytochrome P450 3A4. Toxicology 1995; 104: 1-8
    • (1995) Toxicology , vol.104 , pp. 1-8
    • Li, A.P.1    Kaminski, D.L.2    Rasmussen, A.3
  • 369
    • 0029925714 scopus 로고    scopus 로고
    • Diltiazem enhances the effects of triazolam by inhibiting its metabolism
    • Varhe A, Olkkola KT, Neuvonen PJ. Diltiazem enhances the effects of triazolam by inhibiting its metabolism. Clin Pharmacol Ther 1996; 59: 369-75
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 369-375
    • Varhe, A.1    Olkkola, K.T.2    Neuvonen, P.J.3
  • 370
    • 0029782647 scopus 로고    scopus 로고
    • Erythromycin-felodipine interaction: Magnitude, mechanism, and comparison with grapefruit juice
    • Bailey DG, Bend JR, Arnold MO, et al. Erythromycin-felodipine interaction: magnitude, mechanism, and comparison with grapefruit juice. Clin Pharmacol Ther 1996; 60: 25-33
    • (1996) Clin Pharmacol Ther , vol.60 , pp. 25-33
    • Bailey, D.G.1    Bend, J.R.2    Arnold, M.O.3
  • 371
    • 0028927151 scopus 로고
    • Isradipine. An update of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the treatment of mild to moderate hypertension
    • Brogden RN, Sorkin EM. Isradipine. An update of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the treatment of mild to moderate hypertension. Drugs 1995; 49: 618-49
    • (1995) Drugs , vol.49 , pp. 618-649
    • Brogden, R.N.1    Sorkin, E.M.2
  • 372
    • 0025174133 scopus 로고
    • Clinical pharmacology, pharmacokinetics and hemodynamic effects of nicardipine
    • Singh BN, Josephson MA. Clinical pharmacology, pharmacokinetics and hemodynamic effects of nicardipine. Am Heart J 1990; 119: 427-34
    • (1990) Am Heart J , vol.119 , pp. 427-434
    • Singh, B.N.1    Josephson, M.A.2
  • 373
    • 0027135349 scopus 로고
    • Influence of CYP2D6-dependent metabolism on the steady-state pharmacokinetics and pharmacodynamics of metoprolol and nicardipine, alone and in combination
    • Laurent-Kenesi M-A, Funck-Brentano C, Poirier J-M, et al. Influence of CYP2D6-dependent metabolism on the steady-state pharmacokinetics and pharmacodynamics of metoprolol and nicardipine, alone and in combination. Br J Clin Pharmacol 1993; 36: 531-8
    • (1993) Br J Clin Pharmacol , vol.36 , pp. 531-538
    • Laurent-Kenesi, M.-A.1    Funck-Brentano, C.2    Poirier, J.-M.3
  • 374
    • 0027339926 scopus 로고
    • The influences of dose and ethnic origins on the pharmacokinetics of nifedipine
    • Ahsan CH, Renwick AG, Waller DG, et al. The influences of dose and ethnic origins on the pharmacokinetics of nifedipine. Clin Pharmacol Ther 1993; 54: 329-38
    • (1993) Clin Pharmacol Ther , vol.54 , pp. 329-338
    • Ahsan, C.H.1    Renwick, A.G.2    Waller, D.G.3
  • 375
    • 0029671251 scopus 로고    scopus 로고
    • 5 in the oxidation of testosterone and nifedipine by recombinant cytochrome P450 3A4 and by human liver microsomes
    • 5 in the oxidation of testosterone and nifedipine by recombinant cytochrome P450 3A4 and by human liver microsomes. Arch Biochem Biophys 1996; 325: 174-82
    • (1996) Arch Biochem Biophys , vol.325 , pp. 174-182
    • Yamazaki, H.1    Nakano, M.2    Imai, Y.3
  • 376
    • 0030045954 scopus 로고    scopus 로고
    • The nifedipine gastrointestinal therapeutic system (GITS). Evaluation of pharmaceutical, pharmacokinetic and parmacological properties
    • Grundy JS, Foster RT. The nifedipine gastrointestinal therapeutic system (GITS). Evaluation of pharmaceutical, pharmacokinetic and parmacological properties. Clin Pharmacokinet 1996; 30: 28-51
    • (1996) Clin Pharmacokinet , vol.30 , pp. 28-51
    • Grundy, J.S.1    Foster, R.T.2
  • 377
    • 0029268491 scopus 로고
    • Nimodipine: Potential for drug drug interactions in the elderly
    • Muck W, Ahr G, Kuhlmann J. Nimodipine: potential for drug drug interactions in the elderly. Drugs Aging 1995; 6: 229-42
    • (1995) Drugs Aging , vol.6 , pp. 229-242
    • Muck, W.1    Ahr, G.2    Kuhlmann, J.3
  • 378
    • 0029030691 scopus 로고
    • The effect of age and liver disease on the pharmacokinetics of the calcium antagonist, nisoldipine
    • Davidsson GK, Edwards JS, Davidson C. The effect of age and liver disease on the pharmacokinetics of the calcium antagonist, nisoldipine. Curr Med Res Opin 1995; 13: 285-97
    • (1995) Curr Med Res Opin , vol.13 , pp. 285-297
    • Davidsson, G.K.1    Edwards, J.S.2    Davidson, C.3
  • 379
    • 0028153858 scopus 로고
    • Grapefruit juice and drugs: How significant is the interaction?
    • Bailey DG, Malcolm J, Arnold O, et al. Grapefruit juice and drugs: how significant is the interaction? Clin Pharmacokinet 1994; 26: 91-8
    • (1994) Clin Pharmacokinet , vol.26 , pp. 91-98
    • Bailey, D.G.1    Malcolm, J.2    Arnold, O.3
  • 380
    • 0025737821 scopus 로고
    • Stereoselective pharmacokinetics of oral intravenous nitrendipine in healthy male subjects
    • Soons PA, Breimer DD. Stereoselective pharmacokinetics of oral intravenous nitrendipine in healthy male subjects. Br J Clin Pharmacol 1991; 32: 11-6
    • (1991) Br J Clin Pharmacol , vol.32 , pp. 11-16
    • Soons, P.A.1    Breimer, D.D.2
  • 381
    • 0029591169 scopus 로고
    • Cytochromes of the P450 2C subfamily are the major enzymes involved in the O-demelhylation of verapamil in humans
    • Busse D, Cosme J, Beaune P, et al. Cytochromes of the P450 2C subfamily are the major enzymes involved in the O-demelhylation of verapamil in humans. Naunyn Schmeidebergs Arch Pharmacol 1995; 353: 116-21
    • (1995) Naunyn Schmeidebergs Arch Pharmacol , vol.353 , pp. 116-121
    • Busse, D.1    Cosme, J.2    Beaune, P.3
  • 382
    • 0030066895 scopus 로고    scopus 로고
    • Simultaneous first-order and capacity-limited elimination kinetics after oral administration of verapamil
    • Gupta SK, Hwang S, Atkinson L, et al. Simultaneous first-order and capacity-limited elimination kinetics after oral administration of verapamil. J Clin Pharmacol 1996; 36: 25-34
    • (1996) J Clin Pharmacol , vol.36 , pp. 25-34
    • Gupta, S.K.1    Hwang, S.2    Atkinson, L.3
  • 383
    • 0028303513 scopus 로고
    • Decreased plasma concentrations of imipramine and desipramine following cholestyramine intake in depressed patients
    • Spina E, Avenoso A, Campo GM, et al. Decreased plasma concentrations of imipramine and desipramine following cholestyramine intake in depressed patients. Ther Drug Monitor 1994; 16: 432-4
    • (1994) Ther Drug Monitor , vol.16 , pp. 432-434
    • Spina, E.1    Avenoso, A.2    Campo, G.M.3
  • 384
    • 0018398897 scopus 로고
    • Clofibrate disposition in renal failure and acute and chronic liver disease
    • Gugler R, Kurten JW, Jensen CJ, et al. Clofibrate disposition in renal failure and acute and chronic liver disease. Eur J Clin Pharmacol 1979; 15: 341-7
    • (1979) Eur J Clin Pharmacol , vol.15 , pp. 341-347
    • Gugler, R.1    Kurten, J.W.2    Jensen, C.J.3
  • 385
    • 0026694388 scopus 로고
    • Pharmacokinetics of fluvastatin after single and multiple doses in normal volunteers
    • Tse FLS, Jaffe JM, Troendle A. Pharmacokinetics of fluvastatin after single and multiple doses in normal volunteers. J Clin Pharmacol 1992; 32: 630-8
    • (1992) J Clin Pharmacol , vol.32 , pp. 630-638
    • Tse, F.L.S.1    Jaffe, J.M.2    Troendle, A.3
  • 386
    • 0027146460 scopus 로고
    • Pharmacokinetics of fluvastatin and specific drug interactions
    • Smith HT, Jokubaitis LA, Troendle A-J, et al. Pharmacokinetics of fluvastatin and specific drug interactions. Am J Hypertens 1993; 6: 375S-382S
    • (1993) Am J Hypertens , vol.6
    • Smith, H.T.1    Jokubaitis, L.A.2    Troendle, A.-J.3
  • 387
    • 0028846142 scopus 로고
    • In vivo inhibition profile of cytochrome P450TB (CYP2C9) by (±)-fluvastatin
    • Transon C, Leemann T, Vogl N, et al. In vivo inhibition profile of cytochrome P450TB (CYP2C9) by (±)-fluvastatin. Clin Pharmacol Ther 1995; 58: 412-7
    • (1995) Clin Pharmacol Ther , vol.58 , pp. 412-417
    • Transon, C.1    Leemann, T.2    Vogl, N.3
  • 388
    • 0029143748 scopus 로고
    • Reactivity of gemfibrozil 1-O-β-acyl glucuronide. Pharmacokinetics of covalently bound gemfibrozil-protein adducts in rats
    • Sallustio BC, Foster DJR. Reactivity of gemfibrozil 1-O-β-acyl glucuronide. Pharmacokinetics of covalently bound gemfibrozil-protein adducts in rats. Drug Metab Dispos 1995; 23: 892-9
    • (1995) Drug Metab Dispos , vol.23 , pp. 892-899
    • Sallustio, B.C.1    Foster, D.J.R.2
  • 389
    • 0023677227 scopus 로고
    • Gemfibrozil, a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in dislipidaemia
    • Todd PA, Ward A. Gemfibrozil, a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in dislipidaemia. Drugs 1988; 36: 314-39
    • (1988) Drugs , vol.36 , pp. 314-339
    • Todd, P.A.1    Ward, A.2
  • 390
    • 0025944905 scopus 로고
    • Biotransformation of lovastatin: Identification of cytochrome P450 3A proteins as thé major enzymes responsible for the oxidative metabolism of lovastatin in rat and human liver microsomes
    • Wang RW, Kari PH, Lu AYH, et al. Biotransformation of lovastatin: identification of cytochrome P450 3A proteins as thé major enzymes responsible for the oxidative metabolism of lovastatin in rat and human liver microsomes. Arch Biochem Biophys 1991; 290: 355-61
    • (1991) Arch Biochem Biophys , vol.290 , pp. 355-361
    • Wang, R.W.1    Kari, P.H.2    Lu, A.Y.H.3
  • 391
    • 0023911252 scopus 로고
    • Lovastatin: A new cholesterol-lowering agent
    • McKenney JM. Lovastatin: a new cholesterol-lowering agent. Clin Pharmacokinet 1988; 7: 21-36
    • (1988) Clin Pharmacokinet , vol.7 , pp. 21-36
    • McKenney, J.M.1
  • 392
    • 0029758869 scopus 로고    scopus 로고
    • Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid
    • Neuvonen P, Jalava K-M. Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid. Clin Pharmacol Ther 1996; 60: 54-61
    • (1996) Clin Pharmacol Ther , vol.60 , pp. 54-61
    • Neuvonen, P.1    Jalava, K.-M.2
  • 393
    • 0028168962 scopus 로고
    • Clinical pharmacokinetics of pravastatin
    • Quion JAV, Jones PH. Clinical pharmacokinetics of pravastatin. Clin Pharmacokinet 1994; 27: 94-103
    • (1994) Clin Pharmacokinet , vol.27 , pp. 94-103
    • Quion, J.A.V.1    Jones, P.H.2
  • 394
    • 0027496128 scopus 로고
    • Effects of simvastatin and pravastatin on 6-beta-hydroxycortisol excretion, a potential marker of cytochrome P-450 3A
    • Horsmans Y, Desager JP, Van den Berge V, et al. Effects of simvastatin
    • (1993) Pharmacol Res , vol.28 , pp. 243-248
    • Horsmans, Y.1    Desager, J.P.2    Van Den Berge, V.3
  • 395
    • 0027488452 scopus 로고
    • Pharmacokinetics of pravastatin in elderly versus young men and women
    • Pan HY, Waclawski AP, Funke PT, et al. Pharmacokinetics of pravastatin in elderly versus young men and women. Ann Pharmacother 1993; 27: 1029-33
    • (1993) Ann Pharmacother , vol.27 , pp. 1029-1033
    • Pan, H.Y.1    Waclawski, A.P.2    Funke, P.T.3
  • 396
    • 0027394378 scopus 로고
    • Clinical pharmacokinetics and practical applications of simvastatin
    • Mauro VF. Clinical pharmacokinetics and practical applications of simvastatin. Clin Pharmacokinet 1993; 24: 195-202
    • (1993) Clin Pharmacokinet , vol.24 , pp. 195-202
    • Mauro, V.F.1
  • 397
    • 0029092064 scopus 로고
    • Simvastatin: A reappraisal of its pharmacology and therapeutic efficacy in hypercholesterolaemia
    • Plosker GL, McTavish D. Simvastatin: a reappraisal of its pharmacology and therapeutic efficacy in hypercholesterolaemia. Drugs 1995; 50: 334-63
    • (1995) Drugs , vol.50 , pp. 334-363
    • Plosker, G.L.1    McTavish, D.2
  • 399
    • 0028869716 scopus 로고
    • Doxazosin: An update of its clinical pharmacology and therapeutic applications in hypertension and benign prostatic hyperplasia
    • Fulton B, Wagstaff AJ, Sorkin EM. Doxazosin: An update of its clinical pharmacology and therapeutic applications in hypertension and benign prostatic hyperplasia. Drugs 1995; 49: 295-320
    • (1995) Drugs , vol.49 , pp. 295-320
    • Fulton, B.1    Wagstaff, A.J.2    Sorkin, E.M.3
  • 400
    • 0025238474 scopus 로고
    • Furosemide (Frusemide): A pharmacokinetic/pharmacodynamic review (Pt I)
    • Boles Ponto LL, Schoenwald RD. Furosemide (Frusemide): A pharmacokinetic/pharmacodynamic review (Pt I). Clin Pharmacokinet 1990; 18: 381-408
    • (1990) Clin Pharmacokinet , vol.18 , pp. 381-408
    • Boles Ponto, L.L.1    Schoenwald, R.D.2
  • 402
    • 0028260356 scopus 로고
    • Biotransformation of organic nitrates and vascular smooth muscle cell function
    • Bennett BM, McDonald BJ, Nigam R, et al. Biotransformation of organic nitrates and vascular smooth muscle cell function. Trends Pharmacol Sci 1994; 15: 245-9
    • (1994) Trends Pharmacol Sci , vol.15 , pp. 245-249
    • Bennett, B.M.1    McDonald, B.J.2    Nigam, R.3
  • 403
    • 0028894286 scopus 로고
    • Biotransformation of losartan to its active carboxylic acid metabolite in human liver microsomes: Role of cytochrome P4502C and 3A subfamily members
    • Stearns RA, Chakravarty PK, Chen R, et al. Biotransformation of losartan to its active carboxylic acid metabolite in human liver microsomes: role of cytochrome P4502C and 3A subfamily members. Drug Metab Dispos 1995; 23: 207-15
    • (1995) Drug Metab Dispos , vol.23 , pp. 207-215
    • Stearns, R.A.1    Chakravarty, P.K.2    Chen, R.3
  • 404
    • 0029588499 scopus 로고
    • Pharmacokinetics of losartan, an angiotensin II receptor antagonist, and its active metabolite EXP3174 in humans
    • Lo M-W, Goldberg MR, McCrea JB, et al. Pharmacokinetics of losartan, an angiotensin II receptor antagonist, and its active metabolite EXP3174 in humans. Clin Pharmacol Ther 1995; 58: 641-9
    • (1995) Clin Pharmacol Ther , vol.58 , pp. 641-649
    • Lo, M.-W.1    Goldberg, M.R.2    McCrea, J.B.3
  • 405
    • 0029972753 scopus 로고    scopus 로고
    • Phenobarbital minimally alters plasma concentrations of losartan and its active metabolite E-3174
    • Goldberg MR, Lo MW, Deutch PJ, et al. Phenobarbital minimally alters plasma concentrations of losartan and its active metabolite E-3174. Clin Pharmacol Ther 1996; 59: 268-74
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 268-274
    • Goldberg, M.R.1    Lo, M.W.2    Deutch, P.J.3
  • 407
    • 0028933481 scopus 로고
    • Combined terazosin and verapamil therapy in essential hypertension: Hemodynamic and pharmacokinetic interactions
    • L
    • Lenz ML, Pool J, L, Laddu AR, et al. Combined terazosin and verapamil therapy in essential hypertension: hemodynamic and pharmacokinetic interactions. Am J Hypertens 1995; 8: 133-45
    • (1995) Am J Hypertens , vol.8 , pp. 133-145
    • Lenz, M.L.1    Pool, J.2    Laddu, A.R.3
  • 408
    • 8044227918 scopus 로고
    • Involvement of human liver microsomal cytochrome P450 2C9 in torasemide hydroxylation
    • Miners JO, Rees DLP, Veronese ME, et al. Involvement of human liver microsomal cytochrome P450 2C9 in torasemide hydroxylation. Clin Exp Pharmacol Physiol 1993: 49
    • (1993) Clin Exp Pharmacol Physiol , vol.49
    • Miners, J.O.1    Rees, D.L.P.2    Veronese, M.E.3
  • 409
    • 0028816616 scopus 로고
    • Torasemide: An update of its pharmacological properties and therapeutic efficacy
    • Dunn CJ, Fitton A, Brogden RN. Torasemide: An update of its pharmacological properties and therapeutic efficacy. Drugs 1995; 49: 121-42
    • (1995) Drugs , vol.49 , pp. 121-142
    • Dunn, C.J.1    Fitton, A.2    Brogden, R.N.3
  • 410
    • 0020601435 scopus 로고
    • Pharmacokinetics of triamterene after iv administration to man: Determination of bioavailability
    • Gilfrich HJ, Kremer G, Möhrke W, et al. Pharmacokinetics of triamterene after iv administration to man: determination of bioavailability. Eur J Clin Pharmacol 1983; 25: 237-41
    • (1983) Eur J Clin Pharmacol , vol.25 , pp. 237-241
    • Gilfrich, H.J.1    Kremer, G.2    Möhrke, W.3
  • 411
    • 0022544582 scopus 로고
    • Effect of cimetidine on renal and hepatic drug elimination: Studies with triamterene
    • Muirhead MR, Somogyi AA, Rolan PE, et al. Effect of cimetidine on renal and hepatic drug elimination: studies with triamterene. Clin Pharmacol Ther 1986; 40: 400-7
    • (1986) Clin Pharmacol Ther , vol.40 , pp. 400-407
    • Muirhead, M.R.1    Somogyi, A.A.2    Rolan, P.E.3
  • 413
    • 0028936268 scopus 로고
    • Cardiac electrophysical actions of the histamine H1-receptor antagonists astemizole and terfenadine compared with chlorpheniramine and pyrilamine
    • Salata JJ, Jurkiewicz NK, Wallace AA, et al. Cardiac electrophysical actions of the histamine H1-receptor antagonists astemizole and terfenadine compared with chlorpheniramine and pyrilamine. Circ Res 1995; 76: 110-9
    • (1995) Circ Res , vol.76 , pp. 110-119
    • Salata, J.J.1    Jurkiewicz, N.K.2    Wallace, A.A.3
  • 414
    • 0022472863 scopus 로고
    • Dose-proportionality, bioavailability, and steady-state kinetics of astemizole in man
    • Heykants J, Van Peer A, Woestenborghs R, et al. Dose-proportionality, bioavailability, and steady-state kinetics of astemizole in man. Drug Development Res 1986; 8: 71-8
    • (1986) Drug Development Res , vol.8 , pp. 71-78
    • Heykants, J.1    Van Peer, A.2    Woestenborghs, R.3
  • 416
    • 0020434840 scopus 로고
    • The pharmacokinetics and antihistaminic effects of brompheniramine
    • Simons FER, Frith EM, Simons KJ. The pharmacokinetics and antihistaminic effects of brompheniramine. J Allergy Clin Immunol 1982; 70: 458-64
    • (1982) J Allergy Clin Immunol , vol.70 , pp. 458-464
    • Simons, F.E.R.1    Frith, E.M.2    Simons, K.J.3
  • 417
    • 0028816462 scopus 로고
    • Mepyramine, a histamine H1 receptor antagonist, inhibits the metabolic activity of rat and human P450 2D forms
    • Hiroi T, Ohishi N, Imaoka S, et al. Mepyramine, a histamine H1 receptor antagonist, inhibits the metabolic activity of rat and human P450 2D forms. J Pharmacol Exp Ther 1995; 272: 939-43
    • (1995) J Pharmacol Exp Ther , vol.272 , pp. 939-943
    • Hiroi, T.1    Ohishi, N.2    Imaoka, S.3
  • 418
    • 0027751835 scopus 로고
    • Cetirizine: A reappraisal of its pharmacological properties and therapeutic use in selected allergic disorders
    • Spencer CM, Faulds D, Peters DH. Cetirizine: a reappraisal of its pharmacological properties and therapeutic use in selected allergic disorders. Drugs 1993; 46: 1055-80
    • (1993) Drugs , vol.46 , pp. 1055-1080
    • Spencer, C.M.1    Faulds, D.2    Peters, D.H.3
  • 420
    • 0029558056 scopus 로고
    • Drug interactions and the cytochrorne P-450 enzymes
    • Carlston JA. Drug interactions and the cytochrorne P-450 enzymes. Pediatric Asthma, Allergy Immunol 1995; 9: 123-32
    • (1995) Pediatric Asthma, Allergy Immunol , vol.9 , pp. 123-132
    • Carlston, J.A.1
  • 421
    • 0019997580 scopus 로고
    • Pharmacokinetics of chlorpheniramine after intravenous and oral administration in normal adults
    • Huang S-M, Athanikar NK, Sridhar K, et al. Pharmacokinetics of chlorpheniramine after intravenous and oral administration in normal adults. Eur J Clin Pharmacol 1982; 22: 359-65
    • (1982) Eur J Clin Pharmacol , vol.22 , pp. 359-365
    • Huang, S.-M.1    Athanikar, N.K.2    Sridhar, K.3
  • 422
    • 0025850248 scopus 로고
    • N+-Glucuronidation of aliphatic tertiary amines, a general phenomenon in the metabolism of H1-antihistamines in humans
    • Luo H, Hawes EM, McKay G, et al. N+-Glucuronidation of aliphatic tertiary amines, a general phenomenon in the metabolism of H1-antihistamines in humans. Xenobiotica 1991; 21: 1281-8
    • (1991) Xenobiotica , vol.21 , pp. 1281-1288
    • Luo, H.1    Hawes, E.M.2    McKay, G.3
  • 423
    • 0022535010 scopus 로고
    • Pharmacokinetics of diphenhydramine and a demethylated metabolite following intravenous and oral administration
    • Blyden GT, Greenblatt DJ, Scavone JM, et al. Pharmacokinetics of diphenhydramine and a demethylated metabolite following intravenous and oral administration. J Clin Pharmacol 1986; 26: 529-33
    • (1986) J Clin Pharmacol , vol.26 , pp. 529-533
    • Blyden, G.T.1    Greenblatt, D.J.2    Scavone, J.M.3
  • 425
    • 0028882348 scopus 로고
    • Loratadine administered concomitantly with erythromycin: Pharmacokinetic and electrocardiographic evaluations
    • Brannan MD, Reidenberg P, Radwanski E, et al. Loratadine administered concomitantly with erythromycin: pharmacokinetic and electrocardiographic evaluations. Clin Pharmacol Ther 1995; 58: 269-78
    • (1995) Clin Pharmacol Ther , vol.58 , pp. 269-278
    • Brannan, M.D.1    Reidenberg, P.2    Radwanski, E.3
  • 426
    • 0030048830 scopus 로고    scopus 로고
    • Identification of human liver cytochrorne P450 enzymes that metabolize the non-sedating antihistamine loratadine
    • Yumibe N, Huie K, Chen K-J, et al. Identification of human liver cytochrorne P450 enzymes that metabolize the non-sedating antihistamine loratadine. Biochem Pharmacol 1996; 51: 165-72
    • (1996) Biochem Pharmacol , vol.51 , pp. 165-172
    • Yumibe, N.1    Huie, K.2    Chen, K.-J.3
  • 427
    • 0020659120 scopus 로고
    • Physical and biological properties of pyrilamine
    • Haley TJ. Physical and biological properties of pyrilamine. J Pharm Sci 1983; 72: 3-12
    • (1983) J Pharm Sci , vol.72 , pp. 3-12
    • Haley, T.J.1
  • 428
    • 0028335006 scopus 로고
    • Identification of urinary metabolites of pyrilamine after oral administration to man
    • Chung BC, Kim DH, Jung BH, et al. Identification of urinary metabolites of pyrilamine after oral administration to man. Xenobiotica 1994; 24: 451-9
    • (1994) Xenobiotica , vol.24 , pp. 451-459
    • Chung, B.C.1    Kim, D.H.2    Jung, B.H.3
  • 429
    • 0029040522 scopus 로고
    • Metabolism of terfenadine associated with CYP3A(4) activity in human hepatic microsomes
    • Ling K-HJ, Leeson GS, Burmaster SD, et al. Metabolism of terfenadine associated with CYP3A(4) activity in human hepatic microsomes. Drug Metab Dispos 1995; 23: 631-6
    • (1995) Drug Metab Dispos , vol.23 , pp. 631-636
    • Ling, K.-H.J.1    Leeson, G.S.2    Burmaster, S.D.3
  • 430
    • 0028568568 scopus 로고
    • In vitro prediction of the terfenadine-ketoconazole pharmacokinetic interaction
    • von Moltke LL, Greenblatt DJ, Duan SX, et al. In vitro prediction of the terfenadine-ketoconazole pharmacokinetic interaction. J Clin Pharmacol 1994; 34: 1222-7
    • (1994) J Clin Pharmacol , vol.34 , pp. 1222-1227
    • Von Moltke, L.L.1    Greenblatt, D.J.2    Duan, S.X.3
  • 431
    • 0029124814 scopus 로고
    • In vitro metabolism of terfenadine by a purified recombinant fusion protein containing cytochrome P4503A4 and NADPH-P450 reductase
    • Rodrigues AD, Mulford DJ, Lee RD, et al. In vitro metabolism of terfenadine by a purified recombinant fusion protein containing cytochrome P4503A4 and NADPH-P450 reductase. Drug Metab Dispos 1995; 23: 765-75
    • (1995) Drug Metab Dispos , vol.23 , pp. 765-775
    • Rodrigues, A.D.1    Mulford, D.J.2    Lee, R.D.3
  • 432
    • 0030012246 scopus 로고    scopus 로고
    • Grapefruit juice alters terfenadine pharmacokinetics, resulting in prolongation of repolarization on the electrocardiogram
    • Benton RE, Honig PK, Zamani K, et al. Grapefruit juice alters terfenadine pharmacokinetics, resulting in prolongation of repolarization on the electrocardiogram. Clin Pharmacol Ther 1996; 59: 383-8
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 383-388
    • Benton, R.E.1    Honig, P.K.2    Zamani, K.3
  • 433
    • 0030009690 scopus 로고    scopus 로고
    • Inhibition of terfenadine metabolism in vitro by azole antifungal agents and by selective serotonin reuptake inhibitor antidepressants: Relation to pharmacokinetic interactions in vivo
    • von Moltke LL, Greenblatt DJ, Duan SX, et al. Inhibition of terfenadine metabolism in vitro by azole antifungal agents and by selective serotonin reuptake inhibitor antidepressants: Relation to pharmacokinetic interactions in vivo. J Clin Psychopharmacol 1996; 16: 104-12
    • (1996) J Clin Psychopharmacol , vol.16 , pp. 104-112
    • Von Moltke, L.L.1    Greenblatt, D.J.2    Duan, S.X.3
  • 434
    • 0027168405 scopus 로고
    • Oxidation of the antihistaminic drug terfenadine in human liver microsomes. Role of cytochrorne P-450 3A(4) in N-dealkylation and C-hydroxylation
    • Yun C-H, Okerholm RA, Guengerich FP. Oxidation of the antihistaminic drug terfenadine in human liver microsomes. Role of cytochrorne P-450 3A(4) in N-dealkylation and C-hydroxylation. Drug Metab Dispos 1993; 21: 403-9
    • (1993) Drug Metab Dispos , vol.21 , pp. 403-409
    • Yun, C.-H.1    Okerholm, R.A.2    Guengerich, F.P.3
  • 435
    • 0022559543 scopus 로고
    • 1-receptor antagonist triprolidine: Pharmacokinetics and antihistaminic effects
    • 1-receptor antagonist triprolidine: pharmacokinetics and antihistaminic effects. J Allergy Clin Immunol 1986; 77: 326-30
    • (1986) J Allergy Clin Immunol , vol.77 , pp. 326-330
    • Simons, K.J.1    Singh, M.2    Gillespie, C.A.3
  • 436
    • 0024333023 scopus 로고
    • Cocaine: Pharmacokinetics and biotransformation in man
    • Inaba T. Cocaine: Pharmacokinetics and biotransformation in man. Can J Physiol Pharmacol 1989; 67: 1154-7
    • (1989) Can J Physiol Pharmacol , vol.67 , pp. 1154-1157
    • Inaba, T.1
  • 437
    • 0027513040 scopus 로고
    • Norcaine and N-hydroxynorcocaine formation in human liver microsomes: Role of cytochrome P-4503A4
    • LeDuc BW, Sinclair PR, Shuster L, et al. Norcaine and N-hydroxynorcocaine formation in human liver microsomes: role of cytochrome P-4503A4. Pharmacology 1993; 46: 294-300
    • (1993) Pharmacology , vol.46 , pp. 294-300
    • LeDuc, B.W.1    Sinclair, P.R.2    Shuster, L.3
  • 438
    • 0028897643 scopus 로고
    • The role of CYP enzymes in cocaine-induced liver damage
    • Pasanen M, Pellinen P, Stenbäck F, et al. The role of CYP enzymes in cocaine-induced liver damage. Arch Toxicol 1995; 69: 287-90
    • (1995) Arch Toxicol , vol.69 , pp. 287-290
    • Pasanen, M.1    Pellinen, P.2    Stenbäck, F.3
  • 439
    • 0029868823 scopus 로고    scopus 로고
    • The influence of the sparteine/debrisoquine genetic polymorphism on the disposition of dexfenfluramine
    • Gross AS, Phillips AC, Rieutord A, et al. The influence of the sparteine/debrisoquine genetic polymorphism on the disposition of dexfenfluramine. BrJ Clin Pharmacol 1996; 41: 311-7
    • (1996) BrJ Clin Pharmacol , vol.41 , pp. 311-317
    • Gross, A.S.1    Phillips, A.C.2    Rieutord, A.3
  • 440
    • 0027956791 scopus 로고
    • Characterization of dextromethorphan N-demethylation by human liver microsomes
    • Gorski JC, Jenes DR, Wrighton SA, et al. Characterization of dextromethorphan N-demethylation by human liver microsomes. Biochem Pharmacol 1994; 48: 173-82
    • (1994) Biochem Pharmacol , vol.48 , pp. 173-182
    • Gorski, J.C.1    Jenes, D.R.2    Wrighton, S.A.3
  • 441
    • 0029059649 scopus 로고
    • Pharmacokinetics of dextromethorphan and metabolites in humans: Influence of the CYP2D6 phenotype and quinidine inhibition
    • Schadel M, Wu D, Otton V, et al. Pharmacokinetics of dextromethorphan and metabolites in humans: Influence of the CYP2D6 phenotype and quinidine inhibition. J Clin Psychopharmacol 1995; 15: 263-9
    • (1995) J Clin Psychopharmacol , vol.15 , pp. 263-269
    • Schadel, M.1    Wu, D.2    Otton, V.3
  • 442
    • 0029965231 scopus 로고    scopus 로고
    • Dextromethorphan as an in vivo probe for the simultaneous determination of CYP2D6 and CYP3A activity
    • Ducharme J, Abdullah S, Wainer IW. Dextromethorphan as an in vivo probe for the simultaneous determination of CYP2D6 and CYP3A activity. J Chromatogr B Biomed Appl 1996; 678: 113-8
    • (1996) J Chromatogr B Biomed Appl , vol.678 , pp. 113-118
    • Ducharme, J.1    Abdullah, S.2    Wainer, I.W.3
  • 443
    • 0027518224 scopus 로고
    • Effects of a sauna on the pharmacokinetics and pharmacodynamics of midazolam and ephedrine in healthy young women
    • Vanakoski J, Strömberg C, Seppälä T. Effects of a sauna on the pharmacokinetics and pharmacodynamics of midazolam and ephedrine in healthy young women. Eur J Clin Pharmacol 1993; 45: 377-81
    • (1993) Eur J Clin Pharmacol , vol.45 , pp. 377-381
    • Vanakoski, J.1    Strömberg, C.2    Seppälä, T.3
  • 444
    • 0029017447 scopus 로고
    • Cytochrome P4502D isozymes catalyze the 4-hydroxylation of methamphetamine enantiomers
    • Lin LY, Kumagai Y, Hiratsuka A, et al. Cytochrome P4502D isozymes catalyze the 4-hydroxylation of methamphetamine enantiomers. Drug Metab Dispos 1995; 23: 610-4
    • (1995) Drug Metab Dispos , vol.23 , pp. 610-614
    • Lin, L.Y.1    Kumagai, Y.2    Hiratsuka, A.3
  • 445
    • 0020573799 scopus 로고
    • Pharmacokinetics of methylphenidate in man, rat and monkey
    • Wargin W, Patrick K, Kilts C. Pharmacokinetics of methylphenidate in man, rat and monkey. J Pharmacol Exp Ther 1983; 226: 382-6
    • (1983) J Pharmacol Exp Ther , vol.226 , pp. 382-386
    • Wargin, W.1    Patrick, K.2    Kilts, C.3
  • 446
  • 447
    • 0025085521 scopus 로고
    • Steady state pharmacokinetics and dose-proportionality of phenylpropanolamine in healthy subjects
    • Scherzinger SS, Dowse R, Kanfer I. Steady state pharmacokinetics and dose-proportionality of phenylpropanolamine in healthy subjects. J Clin Pharmacol 1990; 30: 372-7
    • (1990) J Clin Pharmacol , vol.30 , pp. 372-377
    • Scherzinger, S.S.1    Dowse, R.2    Kanfer, I.3
  • 448
    • 0028980987 scopus 로고
    • Pretreatmcnl H2 receptor antagonists that differ in P450 modulation activity: Comparative effects on paclilaxel clearance rates and neutropenia
    • Slichenmeyer WJ, Donehower RC, Chen T-L, et al. Pretreatmcnl H2 receptor antagonists that differ in P450 modulation activity: comparative effects on paclilaxel clearance rates and neutropenia. Cancer Chemother Pharmacol 1995; 36: 227-32
    • (1995) Cancer Chemother Pharmacol , vol.36 , pp. 227-232
    • Slichenmeyer, W.J.1    Donehower, R.C.2    Chen, T.-L.3
  • 450
    • 0029562838 scopus 로고
    • Effect of cimetidine on hepatic cyto-chrome P450: Evidence for formation of a metabolite-intermediate complex
    • Levine M, Bellward GD. Effect of cimetidine on hepatic cyto-chrome P450: Evidence for formation of a metabolite-intermediate complex. Drug Metab Dispos 1995; 23: 1407-11
    • (1995) Drug Metab Dispos , vol.23 , pp. 1407-1411
    • Levine, M.1    Bellward, G.D.2
  • 451
    • 0025357746 scopus 로고
    • Clinical pharmacokinetics of drugs used in the treatment of gastrointestinal dispases (Pt I)
    • Lauritsen K, Laursen LS, Rask-Madsen J. Clinical pharmacokinetics of drugs used in the treatment of gastrointestinal dispases (Pt I). Clin Pharmacokinet 1990; 19: 11-31
    • (1990) Clin Pharmacokinet , vol.19 , pp. 11-31
    • Lauritsen, K.1    Laursen, L.S.2    Rask-Madsen, J.3
  • 452
    • 0030430339 scopus 로고    scopus 로고
    • Identification of the human P450 enzymes involved in lansoprazole metabolism
    • Pearce RE, Rodrigues AD, Goldstein JA, et al. Identification of the human P450 enzymes involved in lansoprazole metabolism. J Pharmacol Exp Ther 1996; 277: 805-16
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 805-816
    • Pearce, R.E.1    Rodrigues, A.D.2    Goldstein, J.A.3
  • 453
    • 0028923801 scopus 로고
    • Oxidative metabolism of lansoprazole by human liver cytochromes P450
    • Pichard L, Curi-Pedrosa R, Bonfils C, et al. Oxidative metabolism of lansoprazole by human liver cytochromes P450. Mol Pharmacol 1995; 47: 410-8
    • (1995) Mol Pharmacol , vol.47 , pp. 410-418
    • Pichard, L.1    Curi-Pedrosa, R.2    Bonfils, C.3
  • 455
    • 0026699994 scopus 로고
    • Increase of cytochrome P4501A2 activity by omeprazole: Evidence by the 13C-[N-3-methyl]-caffeine breath test in poor and extensive metabolizers of S-mephenytoin
    • Rost KL, Brösicke H, Brockmöller J, et al. Increase of cytochrome P4501A2 activity by omeprazole: evidence by the 13C-[N-3-methyl]-caffeine breath test in poor and extensive metabolizers of S-mephenytoin. Clin Pharmacol Ther 1995; 52: 170-80
    • (1995) Clin Pharmacol Ther , vol.52 , pp. 170-180
    • Rost, K.L.1    Brösicke, H.2    Brockmöller, J.3
  • 456
    • 0029138380 scopus 로고
    • Review article: Omeprazole and the cytochrome P450 system
    • Petersen K-U. Review article: omeprazole and the cytochrome P450 system. Aliment Pharmacol Ther 1995; 9: 1-9
    • (1995) Aliment Pharmacol Ther , vol.9 , pp. 1-9
    • Petersen, K.-U.1
  • 457
    • 0029088251 scopus 로고
    • Phenocopies of poor metabolizers of omeprazole caused by liver disease and drug treatment
    • Rost KL, Brockmöller J, Esdorn F, et al. Phenocopies of poor metabolizers of omeprazole caused by liver disease and drug treatment. J Hepatol 1995; 23: 268-77
    • (1995) J Hepatol , vol.23 , pp. 268-277
    • Rost, K.L.1    Brockmöller, J.2    Esdorn, F.3
  • 458
    • 0027145018 scopus 로고
    • Identification of human liver cytochrome P450 isoforms mediating omeprazole metabolism
    • Andersson T, Miners JO, Veronese ME, et al. Identification of human liver cytochrome P450 isoforms mediating omeprazole metabolism. Br J Clin Pharmacol 1993; 36: 521-30
    • (1993) Br J Clin Pharmacol , vol.36 , pp. 521-530
    • Andersson, T.1    Miners, J.O.2    Veronese, M.E.3
  • 459
    • 0026806412 scopus 로고
    • Disposition kinetics and metabolism of omeprazole in extensive and poor metabolizers of S-mephenytoin 4-hydroxylation recruited from an Oriental population
    • Sohn D-R, Kobayashi K, Chiba K, et al. Disposition kinetics and metabolism of omeprazole in extensive and poor metabolizers of S-mephenytoin 4-hydroxylation recruited from an Oriental population. J Pharmacol Exp Ther 1992; 262: 1195-202
    • (1992) J Pharmacol Exp Ther , vol.262 , pp. 1195-1202
    • Sohn, D.-R.1    Kobayashi, K.2    Chiba, K.3
  • 460
    • 0030067605 scopus 로고    scopus 로고
    • Relatively low doses of cisapride in the treatment of nausea in patients treated with venlafaxine for treatment-refractory depression
    • Russell JL. Relatively low doses of cisapride in the treatment of nausea in patients treated with venlafaxine for treatment-refractory depression. J Clin Psychopharmacol 1996; 16: 35-7
    • (1996) J Clin Psychopharmacol , vol.16 , pp. 35-37
    • Russell, J.L.1
  • 461
    • 0000035081 scopus 로고
    • Cisapride and torsades de pointes
    • Ahmad SR, Wolfe SM. Cisapride and torsades de pointes. Lancet 1995; 345: 508
    • (1995) Lancet , vol.345 , pp. 508
    • Ahmad, S.R.1    Wolfe, S.M.2
  • 462
    • 0028089027 scopus 로고
    • Cisapride. An updated review of its pharmacology and therapeutic efficacy as a prokinetic agent in gastrointestinal motility disorders
    • Wiseman LR, Faulds D. Cisapride. An updated review of its pharmacology and therapeutic efficacy as a prokinetic agent in gastrointestinal motility disorders. Drugs 1994; 47: 116-52
    • (1994) Drugs , vol.47 , pp. 116-152
    • Wiseman, L.R.1    Faulds, D.2
  • 463
    • 0029114516 scopus 로고
    • Involvement of CYP2C in the metabolism of cannabinoids by human hepatic microsomes from an old woman
    • Watanabe K, Matsunaga T, Yamamoto I, et al. Involvement of CYP2C in the metabolism of cannabinoids by human hepatic microsomes from an old woman. Biol Pharm Bull 1995; 18: 1138-41
    • (1995) Biol Pharm Bull , vol.18 , pp. 1138-1141
    • Watanabe, K.1    Matsunaga, T.2    Yamamoto, I.3
  • 464
    • 0029147666 scopus 로고
    • Recent advances in the metabolism of cannabinoids
    • Yamamoto I, Watanabe K, Narimatsu S, et al. Recent advances in the metabolism of cannabinoids. Int J Cell Biol 1995; 27: 741-6
    • (1995) Int J Cell Biol , vol.27 , pp. 741-746
    • Yamamoto, I.1    Watanabe, K.2    Narimatsu, S.3
  • 465
    • 0018833864 scopus 로고
    • The pharmacokinetics of metoclopramide in man with observations in the dog
    • Bateman DN, Kahn C, Davies DS. The pharmacokinetics of metoclopramide in man with observations in the dog. Br J Pharmacol 1980; 9: 371-7
    • (1980) Br J Pharmacol , vol.9 , pp. 371-377
    • Bateman, D.N.1    Kahn, C.2    Davies, D.S.3
  • 466
    • 0028856786 scopus 로고
    • Identification and full characterization of a new metabolite of metoclopramide
    • Maurich V, De Amici M, De Micheli C, et al. Identification and full characterization of a new metabolite of metoclopramide. Eur J Med Chemistry 1995; 30: 757-62
    • (1995) Eur J Med Chemistry , vol.30 , pp. 757-762
    • Maurich, V.1    De Amici, M.2    De Micheli, C.3
  • 467
    • 0028229191 scopus 로고
    • The pharmacokinetics of ondansetron after intravenous injection in healthy volunteers phenotyped as poor or extensive metabolisers of debrisoquine
    • Ashforth EIL, Palmer JL, Bye A, et al. The pharmacokinetics of ondansetron after intravenous injection in healthy volunteers phenotyped as poor or extensive metabolisers of debrisoquine. Br J Clin Pharmacol 1994; 37: 389-91
    • (1994) Br J Clin Pharmacol , vol.37 , pp. 389-391
    • Ashforth, E.I.L.1    Palmer, J.L.2    Bye, A.3
  • 468
    • 0028223289 scopus 로고
    • The polymorphic cytochrome P-4502D6 is involved in the metabolism of both 5-hydroxytryptamine antagonists, tropisetron and ondasetron
    • Fischer V, Vickers AEM, Heitz F, et al. The polymorphic cytochrome P-4502D6 is involved in the metabolism of both 5-hydroxytryptamine antagonists, tropisetron and ondasetron. Drug Metab Dispos 1994; 22: 269-74
    • (1994) Drug Metab Dispos , vol.22 , pp. 269-274
    • Fischer, V.1    Vickers, A.E.M.2    Heitz, F.3
  • 469
    • 0029096972 scopus 로고
    • Ondansetron clinical pharmacokinetics
    • Roila F, Del Favero A. Ondansetron clinical pharmacokinetics. Clin Pharmacokinet 1995; 29: 95-109
    • (1995) Clin Pharmacokinet , vol.29 , pp. 95-109
    • Roila, F.1    Del Favero, A.2
  • 470
    • 0028840740 scopus 로고
    • Multiple forms of cytochrome P450 are involved in the metabolism of ondansetron in humans
    • Dixon CM, Colthup PV, Serabjit-Singh CJ, et al. Multiple forms of cytochrome P450 are involved in the metabolism of ondansetron in humans. Drug Metab Dispos 1995; 23: 1225-30
    • (1995) Drug Metab Dispos , vol.23 , pp. 1225-1230
    • Dixon, C.M.1    Colthup, P.V.2    Serabjit-Singh, C.J.3
  • 471
    • 0027197296 scopus 로고
    • Clinical perspectives of some neuroleptics through development and application of their assays
    • Midha KK, Marder SR, Jaworski TJ, et al. Clinical perspectives of some neuroleptics through development and application of their assays. Ther Drug Monitor 1993; 15: 179-89
    • (1993) Ther Drug Monitor , vol.15 , pp. 179-189
    • Midha, K.K.1    Marder, S.R.2    Jaworski, T.J.3
  • 472
    • 0027408928 scopus 로고
    • Prochlorperazine as a doxorubicin-efflux blocker: Phase I clinical and pharmacokinetics studies
    • Sridhar KS, Krishan A, Samy TSA, et al. Prochlorperazine as a doxorubicin-efflux blocker: Phase I clinical and pharmacokinetics studies. Cancer Chemother Pharmacol 1993; 31: 423-30
    • (1993) Cancer Chemother Pharmacol , vol.31 , pp. 423-430
    • Sridhar, K.S.1    Krishan, A.2    Samy, T.S.A.3
  • 473
    • 0025355951 scopus 로고
    • Simultaneous determination of the sulphonylurea glimepiride and its metabolites in human serum and urine by high-performance liquid chromatography after pre-column derivatization
    • Lehr KH, Damm P. Simultaneous determination of the sulphonylurea glimepiride and its metabolites in human serum and urine by high-performance liquid chromatography after pre-column derivatization. J Chromatogr 1990; 526: 497-505
    • (1990) J Chromatogr , vol.526 , pp. 497-505
    • Lehr, K.H.1    Damm, P.2
  • 474
    • 0030003142 scopus 로고    scopus 로고
    • Glimepiride for NIDDM
    • Abramowicz M. Glimepiride for NIDDM. The Med Lett 1996; 38: 47-50
    • (1996) The Med Lett , vol.38 , pp. 47-50
    • Abramowicz, M.1
  • 475
    • 0023944043 scopus 로고
    • Glipizide pharmacokinetics in young and elderly volunteers
    • Kobayashi KA, Bauer LA, Horn JR, et al. Glipizide pharmacokinetics in young and elderly volunteers. Clin Pharmacokinet 1988; 7: 224-8
    • (1988) Clin Pharmacokinet , vol.7 , pp. 224-228
    • Kobayashi, K.A.1    Bauer, L.A.2    Horn, J.R.3
  • 476
    • 0027976649 scopus 로고
    • Slow elimination of glyburide in NIDDM subjects
    • Jonsson A, Rydberg T, Ekberg G, et al. Slow elimination of glyburide in NIDDM subjects. Diabetes Care 1994; 17: 142-5
    • (1994) Diabetes Care , vol.17 , pp. 142-145
    • Jonsson, A.1    Rydberg, T.2    Ekberg, G.3
  • 477
    • 0018703481 scopus 로고
    • Pharmacokinetics of metformin after intravenous and oral administration to man
    • Pentikainen PJ, Neuvonen PJ, Penttila A. Pharmacokinetics of metformin after intravenous and oral administration to man. Eur J Clin Pharmacol 1979; 16: 195-202
    • (1979) Eur J Clin Pharmacol , vol.16 , pp. 195-202
    • Pentikainen, P.J.1    Neuvonen, P.J.2    Penttila, A.3
  • 478
    • 0028913896 scopus 로고
    • Metformin: A review of its pharmacological properties and therapeutic use in non-insulin-dependent diabetes mellitus
    • Dünn CJ, Peters DH. Metformin: A review of its pharmacological properties and therapeutic use in non-insulin-dependent diabetes mellitus. Drugs 1995; 49: 721-49
    • (1995) Drugs , vol.49 , pp. 721-749
    • Dünn, C.J.1    Peters, D.H.2
  • 479
    • 0019783320 scopus 로고
    • Clinical pharmacokinetics of sulphonylurea hypoglycaemic drugs
    • Balant L. Clinical pharmacokinetics of sulphonylurea hypoglycaemic drugs. Clin Pharmacokinet 1981; 6: 215-41
    • (1981) Clin Pharmacokinet , vol.6 , pp. 215-241
    • Balant, L.1
  • 480
    • 0023924549 scopus 로고
    • In vitro inhibition studies of tolbutamide hydroxylase activity of human liver microsomes by azoles, sutphonamides and quinolines
    • Back DJ, Tjia JF, Karbwang J, et al. In vitro inhibition studies of tolbutamide hydroxylase activity of human liver microsomes by azoles, sutphonamides and quinolines. Br J Clin Pharmacol 1988; 26: 23-9
    • (1988) Br J Clin Pharmacol , vol.26 , pp. 23-29
    • Back, D.J.1    Tjia, J.F.2    Karbwang, J.3
  • 481
    • 0029984037 scopus 로고    scopus 로고
    • Metabolism of intravenously administered high-dose 6-mercaptopurine with and without allopurinol treatment in patients with non-Hodgkin lymphoma
    • Keuzenkamp-Jansen CW, De Abreu RA, Bökkerink JPM, et al. Metabolism of intravenously administered high-dose 6-mercaptopurine with and without allopurinol treatment in patients with non-Hodgkin lymphoma. J Pediatric Hematol Oncol 1996; 18: 145-50
    • (1996) J Pediatric Hematol Oncol , vol.18 , pp. 145-150
    • Keuzenkamp-Jansen, C.W.1    De Abreu, R.A.2    Bökkerink, J.P.M.3
  • 482
    • 0025217803 scopus 로고
    • Cyclosporin metabolism in human liver microsomes and its inhibition by other drugs
    • Henricsson S, Lindholm A, Aravolglou M. Cyclosporin metabolism in human liver microsomes and its inhibition by other drugs. Pharmacol Toxicol 1990; 66: 49-52
    • (1990) Pharmacol Toxicol , vol.66 , pp. 49-52
    • Henricsson, S.1    Lindholm, A.2    Aravolglou, M.3
  • 483
    • 0029960192 scopus 로고    scopus 로고
    • Drug interactions and interindividual variability of cyclosporin metabolism in the small intestine
    • Lampen A, Christians U, Bader A, et al. Drug interactions and interindividual variability of cyclosporin metabolism in the small intestine. Pharmacology 1996; 52: 159-68
    • (1996) Pharmacology , vol.52 , pp. 159-168
    • Lampen, A.1    Christians, U.2    Bader, A.3
  • 484
    • 0023921505 scopus 로고
    • Cyclosporine metabolism in human liver: Identification of a cytochrome P450III gene family as the major cyclosporine metabolizing enzyme explains interactions of cyclosporine with other drugs
    • Kronbach T, Fischer V, Meyer UA. Cyclosporine metabolism in human liver: Identification of a cytochrome P450III gene family as the major cyclosporine metabolizing enzyme explains interactions of cyclosporine with other drugs. Clin Pharmacol Ther 1988; 43: 630-5
    • (1988) Clin Pharmacol Ther , vol.43 , pp. 630-635
    • Kronbach, T.1    Fischer, V.2    Meyer, U.A.3
  • 485
    • 0030042485 scopus 로고    scopus 로고
    • Clinically significant drug interactions with cyclosporin, an update
    • Campana C, Regazzi MB, Buggia I, et al. Clinically significant drug interactions with cyclosporin, an update. Clin Pharmacokinet 1996; 30: 141-79
    • (1996) Clin Pharmacokinet , vol.30 , pp. 141-179
    • Campana, C.1    Regazzi, M.B.2    Buggia, I.3
  • 486
    • 0026662551 scopus 로고
    • Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat
    • Sattler M, Guengerich FP, Yun C-H, et al. Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat. Drug Metab Dispos 1992; 20: 753-61
    • (1992) Drug Metab Dispos , vol.20 , pp. 753-761
    • Sattler, M.1    Guengerich, F.P.2    Yun, C.-H.3
  • 487
    • 0028886999 scopus 로고
    • Rapamycin: Distribution, pharmacokinetics, and therapeutic range investigations
    • Yatscoff RW, Wang P, Chan K, et al. Rapamycin: Distribution, pharmacokinetics, and therapeutic range investigations. Ther Drug Monitor 1995; 17: 666-71
    • (1995) Ther Drug Monitor , vol.17 , pp. 666-671
    • Yatscoff, R.W.1    Wang, P.2    Chan, K.3
  • 488
    • 0029922323 scopus 로고    scopus 로고
    • Identification of drugs inhibiting the in vitro metabolism of tacrolimus by human liver microsomes
    • Christians U, Schmidt G, Bader A, et al. Identification of drugs inhibiting the in vitro metabolism of tacrolimus by human liver microsomes. Br J Clin Pharmacol 1996; 41: 187-90
    • (1996) Br J Clin Pharmacol , vol.41 , pp. 187-190
    • Christians, U.1    Schmidt, G.2    Bader, A.3
  • 489
    • 0029560982 scopus 로고
    • Metabolism of the immunosuppressant tacrolimus in the small intestine: Cytochrome P450, drug interactions, and interindividual variability
    • Lampen A, Christians U, Guengerich FP, et al. Metabolism of the immunosuppressant tacrolimus in the small intestine: cytochrome P450, drug interactions, and interindividual variability. Drug Metab Dispos 1995; 23: 1315-24
    • (1995) Drug Metab Dispos , vol.23 , pp. 1315-1324
    • Lampen, A.1    Christians, U.2    Guengerich, F.P.3
  • 490
    • 0030065812 scopus 로고    scopus 로고
    • Interactions of FK506 (tacrolimus) with clinically important drugs
    • Matsuda H, Iwasaki K, Shiraga T, et al. Interactions of FK506 (tacrolimus) with clinically important drugs. Res Commun Mol Pathol Pharmacol 1996; 91: 57-64
    • (1996) Res Commun Mol Pathol Pharmacol , vol.91 , pp. 57-64
    • Matsuda, H.1    Iwasaki, K.2    Shiraga, T.3
  • 491
    • 0028917496 scopus 로고
    • Pharmacokinetics of tacrolimus in liver transplant patients
    • Jusko WJ, Piekoszewski W, Klintmalm GB, et al. Pharmacokinetics of tacrolimus in liver transplant patients. Clin Pharmacol Ther 1995; 57: 281-90
    • (1995) Clin Pharmacol Ther , vol.57 , pp. 281-290
    • Jusko, W.J.1    Piekoszewski, W.2    Klintmalm, G.B.3
  • 492
    • 0028891859 scopus 로고
    • Steady-state kinetics of fluoxetine and amitriptyline in patients treated with a combination of these drugs as compared with those treated with amitriptyline alone
    • El-Yazigi A, Chaleby K, Gad A, et al. Steady-state kinetics of fluoxetine and amitriptyline in patients treated with a combination of these drugs as compared with those treated with amitriptyline alone. J Clin Pharmacol 1995; 35: 17-21
    • (1995) J Clin Pharmacol , vol.35 , pp. 17-21
    • El-Yazigi, A.1    Chaleby, K.2    Gad, A.3
  • 493
    • 0029068546 scopus 로고
    • Fluvoxamine and fluoxetine interaction studies with amitriptyline, clomipramine and neuroleptics in phenotyped patients
    • Vandel S, Bertschy G, Baumann P, et al. Fluvoxamine and fluoxetine interaction studies with amitriptyline, clomipramine and neuroleptics in phenotyped patients. Pharmacol Res 1995; 31: 347-53
    • (1995) Pharmacol Res , vol.31 , pp. 347-353
    • Vandel, S.1    Bertschy, G.2    Baumann, P.3
  • 494
    • 0029557455 scopus 로고
    • Genotypes of cytochrome P450 and clinical response to clomipramine in patients with major depression
    • Bouchez J, Dumur V, Lhermitte M, et al. Genotypes of cytochrome P450 and clinical response to clomipramine in patients with major depression. Euro Psychiatry 1995; 10: 410-2
    • (1995) Euro Psychiatry , vol.10 , pp. 410-412
    • Bouchez, J.1    Dumur, V.2    Lhermitte, M.3
  • 496
    • 0022898438 scopus 로고
    • Importance of oxidative polymorphism and levomepromazine treatment on the steady-state blood concentrations of clomipramine and its major metabolites
    • Balant-Gorgia AE, Balant LP, C. G, et al. Importance of oxidative polymorphism and levomepromazine treatment on the steady-state blood concentrations of clomipramine and its major metabolites. J Clin Pharmacol 1986; 31
    • (1986) J Clin Pharmacol , vol.31
    • Balant-Gorgia, A.E.1    Balant, L.P.2    C., G.3
  • 497
    • 0030010301 scopus 로고    scopus 로고
    • Pharmacokinetic fluvoxamine-clomipramine interaction with favorable therapeutic consequences in therapy-resistant depressive patient
    • Conus P, Bondolfi G, Eap CB, et al. Pharmacokinetic fluvoxamine-clomipramine interaction with favorable therapeutic consequences in therapy-resistant depressive patient. Pharmacopyschiatry 1996; 29: 108-10
    • (1996) Pharmacopyschiatry , vol.29 , pp. 108-110
    • Conus, P.1    Bondolfi, G.2    Eap, C.B.3
  • 498
    • 0030425332 scopus 로고    scopus 로고
    • The biotransformation of clomipramine in vitro, identification of the cytochrome P450s responsible for the separate metabolic pathways
    • Kramir K, Flinois JP, Beaune P, et al. The biotransformation of clomipramine in vitro, identification of the cytochrome P450s responsible for the separate metabolic pathways. J Pharmacol ExpTher 1996; 277: 1659-64
    • (1996) J Pharmacol ExpTher , vol.277 , pp. 1659-1664
    • Kramir, K.1    Flinois, J.P.2    Beaune, P.3
  • 499
    • 0026552617 scopus 로고
    • Quantification and mechanism of the fluoxetine and tricyclic antidepressant interaction
    • Bergstrom RF, Peyton AL, Lemberger L. Quantification and mechanism of the fluoxetine and tricyclic antidepressant interaction. Clin Pharmacol Ther 1992; 51: 239-48
    • (1992) Clin Pharmacol Ther , vol.51 , pp. 239-248
    • Bergstrom, R.F.1    Peyton, A.L.2    Lemberger, L.3
  • 500
    • 0024342596 scopus 로고
    • Quinidine inhibits the 2-hydroxylation of imipramine and desipramine but not the demethylation of imipramine
    • Brosen K, Gram LF. Quinidine inhibits the 2-hydroxylation of imipramine and desipramine but not the demethylation of imipramine. Eur J Clin Pharmacol 1989; 37: 155-60
    • (1989) Eur J Clin Pharmacol , vol.37 , pp. 155-160
    • Brosen, K.1    Gram, L.F.2
  • 501
    • 0021825307 scopus 로고
    • Inhibition of desmethylimipramine 2-hydroxylation by drugs in human liver microsomes
    • von Bahr C, Spina E, Birgersson C, et al. Inhibition of desmethylimipramine 2-hydroxylation by drugs in human liver microsomes. Biochem Pharmacol 1985; 34: 2501-5
    • (1985) Biochem Pharmacol , vol.34 , pp. 2501-2505
    • Von Bahr, C.1    Spina, E.2    Birgersson, C.3
  • 502
    • 0023905440 scopus 로고
    • First-pass metabolism of imipramine and desipramine: Impact of the sparteine oxidation phenotype
    • Brosen K, Gram LF. First-pass metabolism of imipramine and desipramine: impact of the sparteine oxidation phenotype. Clin Pharmacol Ther 1988; 43: 400-6
    • (1988) Clin Pharmacol Ther , vol.43 , pp. 400-406
    • Brosen, K.1    Gram, L.F.2
  • 503
    • 0026556556 scopus 로고
    • Interindividual variability in the N-sulphation of desipramine in human liver and platelets
    • Romiti P, Giuliani L, Pacifici GM. Interindividual variability in the N-sulphation of desipramine in human liver and platelets. Br J Clin Pharmacokinet 1992; 33: 17-23
    • (1992) Br J Clin Pharmacokinet , vol.33 , pp. 17-23
    • Romiti, P.1    Giuliani, L.2    Pacifici, G.M.3
  • 504
    • 0030040670 scopus 로고    scopus 로고
    • Phenobarbital induces the 2-hydroxylation of desipramine
    • Spina E, Avenoso A, Campo GM, et al. Phenobarbital induces the 2-hydroxylation of desipramine. Ther Drug Monitor 1996; 18: 60-4
    • (1996) Ther Drug Monitor , vol.18 , pp. 60-64
    • Spina, E.1    Avenoso, A.2    Campo, G.M.3
  • 505
    • 0020639904 scopus 로고
    • Multiple-dose doxepin kinetics in depressed patients
    • Faulkner RD, Pitts WM, Lee CS, et al. Multiple-dose doxepin kinetics in depressed patients. Clin Pharmacol Ther 1983; 34: 509-15
    • (1983) Clin Pharmacol Ther , vol.34 , pp. 509-515
    • Faulkner, R.D.1    Pitts, W.M.2    Lee, C.S.3
  • 506
    • 0023877814 scopus 로고
    • Pharmacokinetic factors affecting antidepressant drug clearance and clinical effect: Evaluation of doxepin and imipramine. New data and review
    • Ereshefsky L, Tran-Johnson T, Davis CM, et al. Pharmacokinetic factors affecting antidepressant drug clearance and clinical effect: Evaluation of doxepin and imipramine. New data and review. Clin Chem 1988; 34: 863-80
    • (1988) Clin Chem , vol.34 , pp. 863-880
    • Ereshefsky, L.1    Tran-Johnson, T.2    Davis, C.M.3
  • 507
    • 0028969436 scopus 로고
    • Imipramine metabolism in relation to the sparteine and mephenytoin oxidation polymorphisms: A population study
    • Madsen H, Kramer N, K, Brosen K. Imipramine metabolism in relation to the sparteine and mephenytoin oxidation polymorphisms: a population study. Br J Clin Pharmacol 1995; 39: 433-9
    • (1995) Br J Clin Pharmacol , vol.39 , pp. 433-439
    • Madsen, H.1    Kramer, N.K.2    Brosen, K.3
  • 508
    • 0026795695 scopus 로고
    • Inhibitors of imipramine metabolism by human liver microsomes
    • Skjelbo E, Brosen K. Inhibitors of imipramine metabolism by human liver microsomes. Br J Clin Pharmacol 1992; 34: 256-61
    • (1992) Br J Clin Pharmacol , vol.34 , pp. 256-261
    • Skjelbo, E.1    Brosen, K.2
  • 509
    • 0027945112 scopus 로고
    • Metabolic disposition of imipramine in Oriental subjects; relation to metropolol α-hydroxylation and S-mephenytoin 4-hydroxylation phenotypes
    • Koyama E, Sohn D-R, Shin S-G, et al. Metabolic disposition of imipramine in Oriental subjects; relation to metropolol α-hydroxylation and S-mephenytoin 4-hydroxylation phenotypes. J Pharmacol Exp Ther 1994; 271: 860-7
    • (1994) J Pharmacol Exp Ther , vol.271 , pp. 860-867
    • Koyama, E.1    Sohn, D.-R.2    Shin, S.-G.3
  • 510
    • 0030022593 scopus 로고    scopus 로고
    • Paroxetine shifts imipramine metabolism
    • Albers LJ, Reist C, Helmeste D, et al. Paroxetine shifts imipramine metabolism. Psychiatry Res 1996; 59: 189-96
    • (1996) Psychiatry Res , vol.59 , pp. 189-196
    • Albers, L.J.1    Reist, C.2    Helmeste, D.3
  • 511
    • 0023854892 scopus 로고
    • Multiple-dose pharmacokinetics of imipramine and its major active and conjugated metabolites in depressed patients
    • Sutfin TA, Perini GI, Molnar G, et al. Multiple-dose pharmacokinetics of imipramine and its major active and conjugated metabolites in depressed patients. J Clin Psychopharmacol 1988; 8: 48-53
    • (1988) J Clin Psychopharmacol , vol.8 , pp. 48-53
    • Sutfin, T.A.1    Perini, G.I.2    Molnar, G.3
  • 512
    • 0027230584 scopus 로고
    • Major pathway of imipramine metabolism is catalyzed by cytochromes P-450 1A2 and P-450 3A4 in human liver
    • Lemoine A, Gautier JC, Azoulay D, et al. Major pathway of imipramine metabolism is catalyzed by cytochromes P-450 1A2 and P-450 3A4 in human liver. Mol Pharmacol 1993; 43: 827-32
    • (1993) Mol Pharmacol , vol.43 , pp. 827-832
    • Lemoine, A.1    Gautier, J.C.2    Azoulay, D.3
  • 513
    • 0019449455 scopus 로고
    • E- And Z-10-hydroxylation of nortriptyline: Relationship to polymorphic debrisoquine hydroxylation
    • McIlström B, Bertilsson L, Säwe J, et al. E- and Z-10-hydroxylation of nortriptyline: Relationship to polymorphic debrisoquine hydroxylation. Clin Pharmacol Ther 1981; 30: 189-93
    • (1981) Clin Pharmacol Ther , vol.30 , pp. 189-193
    • McIlström, B.1    Bertilsson, L.2    Säwe, J.3
  • 514
    • 0019199097 scopus 로고
    • Nortriptyline and antipyrine clearance in relation to debrisoquine hydroxylation in man
    • Bertilsson L, Elchelbaum M, Mellström B, et al. Nortriptyline and antipyrine clearance in relation to debrisoquine hydroxylation in man. Life Sci 1980; 27: 1673-7
    • (1980) Life Sci , vol.27 , pp. 1673-1677
    • Bertilsson, L.1    Elchelbaum, M.2    Mellström, B.3
  • 515
    • 0029147975 scopus 로고
    • Paroxetine increases serum trimipramine concentration. A report of two cases
    • Leinonen E, Koponen HJ, Lepola U. Paroxetine increases serum trimipramine concentration. A report of two cases. Human Psychopharmacology 1995; 10: 345-7
    • (1995) Human Psychopharmacology , vol.10 , pp. 345-347
    • Leinonen, E.1    Koponen, H.J.2    Lepola, U.3
  • 516
  • 517
    • 0028787766 scopus 로고
    • Bupropion: A review of its mechanism of antidepressant activity
    • Ascher JA, Cole JO, Colin J-N, et al. Bupropion: A review of its mechanism of antidepressant activity. J Clin Psychiatry 1995; 56: 395-401
    • (1995) J Clin Psychiatry , vol.56 , pp. 395-401
    • Ascher, J.A.1    Cole, J.O.2    Colin, J.-N.3
  • 518
    • 0029549892 scopus 로고
    • Effect of fluoxetine, norfluoxetine, sertraline and desmethyl sertraline on human CYP3A catalyzed 1-hydroxy midazolam formation in vitro
    • Ring BJ, Binkley SN, Roskos L, et al. Effect of fluoxetine, norfluoxetine, sertraline and desmethyl sertraline on human CYP3A catalyzed 1-hydroxy midazolam formation in vitro. J Pharmacol Exp Ther 1995; 275: 1131-5
    • (1995) J Pharmacol Exp Ther , vol.275 , pp. 1131-1135
    • Ring, B.J.1    Binkley, S.N.2    Roskos, L.3
  • 519
    • 0025826069 scopus 로고
    • Adverse effects and drug interactions and associated with fluoxetine therapy
    • Levinson ML, Lipsy RJ, Fuller DK. Adverse effects and drug interactions and associated with fluoxetine therapy. DICP Ann Pharmacother 1991; 25: 657-61
    • (1991) DICP Ann Pharmacother , vol.25 , pp. 657-661
    • Levinson, M.L.1    Lipsy, R.J.2    Fuller, D.K.3
  • 520
    • 0028903368 scopus 로고
    • Fluoxetine: An overview of its pharmacodynamic and pharmacokinetic properties and review of its therapeutic efficacy in obsessive-compulsive disorder
    • Bulton B, McTavish D. Fluoxetine: an overview of its pharmacodynamic and pharmacokinetic properties and review of its therapeutic efficacy in obsessive-compulsive disorder. CNS Drugs 1995; 3: 305-22
    • (1995) CNS Drugs , vol.3 , pp. 305-322
    • Bulton, B.1    McTavish, D.2
  • 521
    • 0027442014 scopus 로고
    • Interaction of the enantiomers of fluoxetine and norfluoxetine with human liver cytochromes P450
    • Stevens JC, Wrighton SA. Interaction of the enantiomers of fluoxetine and norfluoxetine with human liver cytochromes P450. J Pharmacol Exp Ther 1993; 266: 964-71
    • (1993) J Pharmacol Exp Ther , vol.266 , pp. 964-971
    • Stevens, J.C.1    Wrighton, S.A.2
  • 522
    • 0028842707 scopus 로고
    • The effects of selective serotonin reuptake inhibitors and their metabolites on S-mephenytoin 4-hydroxylase activity in human liver microsomes
    • Kohayashi K, Yamamoto T, Chiba K, et al. The effects of selective serotonin reuptake inhibitors and their metabolites on S-mephenytoin 4-hydroxylase activity in human liver microsomes. Br J Clin Pharmacol 1995; 40: 481-5
    • (1995) Br J Clin Pharmacol , vol.40 , pp. 481-485
    • Kohayashi, K.1    Yamamoto, T.2    Chiba, K.3
  • 523
    • 0029827303 scopus 로고    scopus 로고
    • The disposition of fluoxetine but not sertraline is altered in poor metabolizers of debrisoquin
    • Hamelin BA, Turgeon J, Vallée F, et al. The disposition of fluoxetine but not sertraline is altered in poor metabolizers of debrisoquin. Clin Pharmacol Ther 1996; 60: 512-21
    • (1996) Clin Pharmacol Ther , vol.60 , pp. 512-521
    • Hamelin, B.A.1    Turgeon, J.2    Vallée, F.3
  • 524
    • 0029160813 scopus 로고
    • Overview of the pharmacokinetics of fluvoxamine
    • van Harten J. Overview of the pharmacokinetics of fluvoxamine. Clin Pharmacokinet 1995; 29: 1-9
    • (1995) Clin Pharmacokinet , vol.29 , pp. 1-9
    • Van Harten, J.1
  • 525
    • 0028318740 scopus 로고
    • Pharmacogenetic aspects in the metabolism of psychotropic drugs: Pharmacokinetic and clinical implications
    • Spina E, Caputi AP. Pharmacogenetic aspects in the metabolism of psychotropic drugs: Pharmacokinetic and clinical implications. Pharmacol Res 1994; 29: 121-37
    • (1994) Pharmacol Res , vol.29 , pp. 121-137
    • Spina, E.1    Caputi, A.P.2
  • 526
    • 0028898044 scopus 로고
    • Selective serotonin reuptake inhibitors and theophylline metabolism in human liver microsomes: Potent inhibition by fluvoxamine
    • Rasmussen BB, Mäenpää J, Pelkonen O, et al. Selective serotonin reuptake inhibitors and theophylline metabolism in human liver microsomes: potent inhibition by fluvoxamine. Br J Clin Pharmacokinet 1995; 39: 151-9
    • (1995) Br J Clin Pharmacokinet , vol.39 , pp. 151-159
    • Rasmussen, B.B.1    Mäenpää, J.2    Pelkonen, O.3
  • 527
    • 0029145903 scopus 로고
    • Drug interactions and the cytochrome P450 system: The role of cytochrome P450 1A2
    • Brøsen K. Drug interactions and the cytochrome P450 system: the role of cytochrome P450 1A2. Clin Pharmacokinet 1995; 29: 20-5
    • (1995) Clin Pharmacokinet , vol.29 , pp. 20-25
    • Brøsen, K.1
  • 528
    • 0029860967 scopus 로고    scopus 로고
    • Disposition of fluvoxamine in humans is determined by the polymorphic CYP2D6 and also by the CYP1A2 activity
    • Carrillo JA, Dahl M-L, Svensson J-O, et al. Disposition of fluvoxamine in humans is determined by the polymorphic CYP2D6 and also by the CYP1A2 activity. Clin Pharmacol Ther 1996; 60: 183-90
    • (1996) Clin Pharmacol Ther , vol.60 , pp. 183-190
    • Carrillo, J.A.1    Dahl, M.-L.2    Svensson, J.-O.3
  • 529
    • 0029824249 scopus 로고    scopus 로고
    • In vivo inhibition of CYP2C19 but not CYP2D6 by fluvoxamine
    • Xu Z-H, Xie H-G, Zhou H-H. In vivo inhibition of CYP2C19 but not CYP2D6 by fluvoxamine. Br J Clin Pharmacol 1996; 42: 518-21
    • (1996) Br J Clin Pharmacol , vol.42 , pp. 518-521
    • Xu, Z.-H.1    Xie, H.-G.2    Zhou, H.-H.3
  • 531
    • 0028282613 scopus 로고
    • Maprotiline metabolism appears to cosegregate with genetically-determined CYP2D6 polymorphic hydroxylation of debrisoquine
    • Firkusny L, Gleiter CH. Maprotiline metabolism appears to cosegregate with genetically-determined CYP2D6 polymorphic hydroxylation of debrisoquine. Br J Clin Pharmacol 1994; 37: 383-8
    • (1994) Br J Clin Pharmacol , vol.37 , pp. 383-388
    • Firkusny, L.1    Gleiter, C.H.2
  • 532
    • 0029584313 scopus 로고
    • Coadministration of nefazodone and benzodiazepines: III. A pharmacokinetic interaction study with alprazolam
    • Greene DS, Salazar DE, Dockens RC, et al. Coadministration of nefazodone and benzodiazepines: III. A pharmacokinetic interaction study with alprazolam. J Clin Psychopharmacol 1995; 15: 399-408
    • (1995) J Clin Psychopharmacol , vol.15 , pp. 399-408
    • Greene, D.S.1    Salazar, D.E.2    Dockens, R.C.3
  • 533
    • 0028828577 scopus 로고
    • Coadministration of nefazodone and benzodiazepines: II. A pharmacokinetic interaction study with triazolam
    • Barbhaiya RH, Shukla UA, Kroboth PD, et al. Coadministration of nefazodone and benzodiazepines: II. A pharmacokinetic interaction study with triazolam. J Clin Psychopharmacol 1995; 15: 320-6
    • (1995) J Clin Psychopharmacol , vol.15 , pp. 320-326
    • Barbhaiya, R.H.1    Shukla, U.A.2    Kroboth, P.D.3
  • 534
    • 0030046921 scopus 로고    scopus 로고
    • Investigation of pharmacokinetic and pharmacodynamic interactions after Coadministration of nefazodone and haloperidol
    • Barbhaiya RH, Shukla UA, Greene DS, et al. Investigation of pharmacokinetic and pharmacodynamic interactions after Coadministration of nefazodone and haloperidol. J Clin Psychopharmacol 1996; 16: 26-34
    • (1996) J Clin Psychopharmacol , vol.16 , pp. 26-34
    • Barbhaiya, R.H.1    Shukla, U.A.2    Greene, D.S.3
  • 535
    • 0029979348 scopus 로고    scopus 로고
    • Inhibition of cytochrome P450 by nefazodone in vitro: Studies of dextromethorphan O- And N-demethylation
    • Schmider J, Greenblatt DJ, Von Moltke LL, et al. Inhibition of cytochrome P450 by nefazodone in vitro: studies of dextromethorphan O- and N-demethylation. Br J Clin Pharmacol 1996; 41: 339-43
    • (1996) Br J Clin Pharmacol , vol.41 , pp. 339-343
    • Schmider, J.1    Greenblatt, D.J.2    Von Moltke, L.L.3
  • 536
    • 0030023969 scopus 로고    scopus 로고
    • A study of the effect of age and gender on the pharmacokinetics of nefazodone after single and multiple doses
    • Barbhaiya RH, Buch AB, Greene DS. A study of the effect of age and gender on the pharmacokinetics of nefazodone after single and multiple doses. J Clin Psychopharmacol 1996; 16: 19-25
    • (1996) J Clin Psychopharmacol , vol.16 , pp. 19-25
    • Barbhaiya, R.H.1    Buch, A.B.2    Greene, D.S.3
  • 537
    • 0029120535 scopus 로고
    • The contribution of pre-clinical drug evaluation in predicting the clinical profile of the selective serotonin reuptake inhibitor paroxetine
    • Kelly JP, E. LB. The contribution of pre-clinical drug evaluation in predicting the clinical profile of the selective serotonin reuptake inhibitor paroxetine. J Serotonin Res 1995; 1: 27-46
    • (1995) J Serotonin Res , vol.1 , pp. 27-46
    • Kelly, J.P.1    E., L.B.2
  • 538
    • 0026576928 scopus 로고
    • Pharmacokinetics of the selective serotonin reuptake inhibitor paroxetine: Nonlinearity and relation to the sparteine oxidation polymorphism
    • Sindrup SH, Brosen K, Gram LF. Pharmacokinetics of the selective serotonin reuptake inhibitor paroxetine: nonlinearity and relation to the sparteine oxidation polymorphism. Clin Pharmacol Ther 1992; 51: 288-95
    • (1992) Clin Pharmacol Ther , vol.51 , pp. 288-295
    • Sindrup, S.H.1    Brosen, K.2    Gram, L.F.3
  • 539
    • 0028603653 scopus 로고
    • Pharmacogenetics and drug metabolism of newer antidepressant agents
    • DeVane CL. Pharmacogenetics and drug metabolism of newer antidepressant agents. J Clin Psychiatry 1994; 55: 38-45
    • (1994) J Clin Psychiatry , vol.55 , pp. 38-45
    • DeVane, C.L.1
  • 540
    • 0026787192 scopus 로고
    • The effect of selective serotonin re-uptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes
    • Crewe HK, Lennard MS, Tucker GT, et al. The effect of selective serotonin re-uptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes. Br J Clin Pharmacol 1992; 34: 262-5
    • (1992) Br J Clin Pharmacol , vol.34 , pp. 262-265
    • Crewe, H.K.1    Lennard, M.S.2    Tucker, G.T.3
  • 541
    • 0025453622 scopus 로고
    • Adverse interactions encountered when using trazodone to treat insomnia associated with fluoxetine
    • Metz A, Shader RI. Adverse interactions encountered when using trazodone to treat insomnia associated with fluoxetine. International Journal of Clin Psychopharmacol 1990; 5: 191-4
    • (1990) International Journal of Clin Psychopharmacol , vol.5 , pp. 191-194
    • Metz, A.1    Shader, R.I.2
  • 542
    • 0029156976 scopus 로고
    • Inhibition of trazodone metabolism by thioridazine in humans
    • Yasui N, Otani K, Kaneko S, et al. Inhibition of trazodone metabolism by thioridazine in humans. Ther Drug Monitor 1995; 17: 333-5
    • (1995) Ther Drug Monitor , vol.17 , pp. 333-335
    • Yasui, N.1    Otani, K.2    Kaneko, S.3
  • 543
    • 0029142536 scopus 로고
    • Effects of various factors on steady state plasma concentrations of trazodone and its active metabolite m-chlorophenylpiperazine
    • Ishida M, Otani K, Kaneko S, et al. Effects of various factors on steady state plasma concentrations of trazodone and its active metabolite m-chlorophenylpiperazine. Int Clin Psychopharmacol 1995; 10: 143-6
    • (1995) Int Clin Psychopharmacol , vol.10 , pp. 143-146
    • Ishida, M.1    Otani, K.2    Kaneko, S.3
  • 544
    • 0028962073 scopus 로고
    • Venlafaxine: A structurally unique and novel antidepressant
    • Morton AW, Sonne SC, Verga MA. Venlafaxine: a structurally unique and novel antidepressant. Ann Pharmacother 1995; 29: 387-95
    • (1995) Ann Pharmacother , vol.29 , pp. 387-395
    • Morton, A.W.1    Sonne, S.C.2    Verga, M.A.3
  • 545
    • 0030045095 scopus 로고    scopus 로고
    • Venlafaxine oxidation in vitro is catalysed by CYP2D6
    • Otton SV, Ball SE, Cheung SW, et al. Venlafaxine oxidation in vitro is catalysed by CYP2D6. Br J Clin Pharmacol 1996; 41: 149-56
    • (1996) Br J Clin Pharmacol , vol.41 , pp. 149-156
    • Otton, S.V.1    Ball, S.E.2    Cheung, S.W.3
  • 546
    • 0029863975 scopus 로고    scopus 로고
    • Biotransformation of'chlorpromazine and methdilazine by Cunninghamella elegans
    • Zhang D, Freeman JP, Sutherland JB, et al. Biotransformation of'chlorpromazine and methdilazine by Cunninghamella elegans, App Environ Microbiol 1996; 62; 798-803
    • (1996) App Environ Microbiol , vol.62 , pp. 798-803
    • Zhang, D.1    Freeman, J.P.2    Sutherland, J.B.3
  • 547
    • 0028944753 scopus 로고
    • Metabolism and bioactivation of clozapine by human liver in vitro
    • Pirmohamed M, Williams D, Madden S, et al. Metabolism and bioactivation of clozapine by human liver in vitro. J Pharmacol Exp Ther 1995; 272: 984-90
    • (1995) J Pharmacol Exp Ther , vol.272 , pp. 984-990
    • Pirmohamed, M.1    Williams, D.2    Madden, S.3
  • 548
    • 0028052932 scopus 로고
    • Serum concentrations of clozapine and its major metabolites: Effects of cotreatment with fluoxetine or valproate
    • Centorrino F, Baldessarini RJ, Kando J, et al. Serum concentrations of clozapine and its major metabolites: Effects of cotreatment with fluoxetine or valproate. Am J Psychriatry 1994; 151: 123-5
    • (1994) Am J Psychriatry , vol.151 , pp. 123-125
    • Centorrino, F.1    Baldessarini, R.J.2    Kando, J.3
  • 549
    • 0028307888 scopus 로고
    • Disposition of clozapine in man: Lack of association with debrisoquine and S-mephenytoin hydroxylation polymorphisms
    • Dahl M-L, Llerena A, Bondesson U, et al. Disposition of clozapine in man: lack of association with debrisoquine and S-mephenytoin hydroxylation polymorphisms. Br J Clin Pharmacokinet 1994; 37: 71-4
    • (1994) Br J Clin Pharmacokinet , vol.37 , pp. 71-74
    • Dahl, M.-L.1    Llerena, A.2    Bondesson, U.3
  • 550
    • 0028318482 scopus 로고
    • Fluvoxamine inhibition and carbamazepine induction of the metabolism of clozapine: Evidence from a therapeutic drug monitoring service
    • Jerling M, Linström L, Bondesson U, et al. Fluvoxamine inhibition and carbamazepine induction of the metabolism of clozapine: Evidence from a therapeutic drug monitoring service. Ther Drug Monitor 1994; 16: 368-74
    • (1994) Ther Drug Monitor , vol.16 , pp. 368-374
    • Jerling, M.1    Linström, L.2    Bondesson, U.3
  • 551
    • 0009404019 scopus 로고    scopus 로고
    • Pharmacokinetics of clozapine and risperidone: A review of recent literature
    • Byerly MJ, DeVane CL. Pharmacokinetics of clozapine and risperidone: A review of recent literature. J Clin Psychopharmacol 1996; 16: 177-87
    • (1996) J Clin Psychopharmacol , vol.16 , pp. 177-187
    • Byerly, M.J.1    DeVane, C.L.2
  • 552
    • 0028843247 scopus 로고
    • Intra- And interethnic variability in reduced haloperidol to haloperidol ratios
    • Lam YWF, Jann MW, Chang W-h, et al. Intra- and interethnic variability in reduced haloperidol to haloperidol ratios. J Clin Pharmacol 1995; 35: 128-36
    • (1995) J Clin Pharmacol , vol.35 , pp. 128-136
    • Lam, Y.W.F.1    Jann, M.W.2    W-h, C.3
  • 553
    • 0027229530 scopus 로고
    • Effect of quinidine on the interconversions kinetics between haloperidol and reduced haloperidol in humans: Implications for the involvement of cytochrome P450IID6
    • Young D, Midha KK, Fossler MJ, et al. Effect of quinidine on the interconversions kinetics between haloperidol and reduced haloperidol in humans: implications for the involvement of cytochrome P450IID6. Eur J Clin Pharmacol 1993; 44: 433-8
    • (1993) Eur J Clin Pharmacol , vol.44 , pp. 433-438
    • Young, D.1    Midha, K.K.2    Fossler, M.J.3
  • 554
    • 0028358360 scopus 로고
    • Metabolism of haloperidol: Clinical implications and unanswered questions
    • Tsang MW, Shader Ri, Greenblatt DJ. Metabolism of haloperidol: Clinical implications and unanswered questions. Clin Psychopharmacol 1994; 14: 159-62
    • (1994) Clin Psychopharmacol , vol.14 , pp. 159-162
    • Tsang, M.W.1    Ri, S.2    Greenblatt, D.J.3
  • 555
    • 0028811154 scopus 로고
    • Studies on metabolism of haloperidol (HP): The role of CYP3A in the production of the neurotoxic pyridinium metabolite HPP+ found in rat brain following IP administration of HP
    • Igarashi K, Kasuya F, Fukui M, et al. Studies on metabolism of haloperidol (HP): The role of CYP3A in the production of the neurotoxic pyridinium metabolite HPP+ found in rat brain following IP administration of HP. Life Sci 1995; 57: 2439-46
    • (1995) Life Sci , vol.57 , pp. 2439-2446
    • Igarashi, K.1    Kasuya, F.2    Fukui, M.3
  • 556
    • 0024333471 scopus 로고
    • Disposition of perphenazine is related to polymorphic debrisoquin hydroxylation in human beings
    • Dahl-Puustinen M-L, Lidén A, Alm C, et al. Disposition of perphenazine is related to polymorphic debrisoquin hydroxylation in human beings. Clin Pharmacol Ther 1989; 46: 78-81
    • (1989) Clin Pharmacol Ther , vol.46 , pp. 78-81
    • Dahl-Puustinen, M.-L.1    Lidén, A.2    Alm, C.3
  • 557
    • 0029053686 scopus 로고
    • Comparison of the kinetic interactions of the neuroleptics perphenazine and zuclopentihixol with tricyclic antidepressives
    • Linnet K. Comparison of the kinetic interactions of the neuroleptics perphenazine and zuclopentihixol with tricyclic antidepressives. Ther Drug Monitor 1995; 17: 308-11
    • (1995) Ther Drug Monitor , vol.17 , pp. 308-311
    • Linnet, K.1
  • 558
    • 0029930015 scopus 로고    scopus 로고
    • The CYP2D6 genotype predicts the oral clearance of the neuroleptic agents perphenazine and zuclopenthixol
    • Jerling M, Dahl M-L, Åberg-Wistedt A, et al. The CYP2D6 genotype predicts the oral clearance of the neuroleptic agents perphenazine and zuclopenthixol. Clin Pharmacol Ther 1996; 59: 423-8
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 423-428
    • Jerling, M.1    Dahl, M.-L.2    Åberg-Wistedt, A.3
  • 559
    • 0029738332 scopus 로고    scopus 로고
    • Steady-state serum concentrations of the neuroleptic perphenazine in relation to CYP2D6 genetic polymorphism
    • Linnet K, Wiborg O. Steady-state serum concentrations of the neuroleptic perphenazine in relation to CYP2D6 genetic polymorphism. Clin Pharmacol Ther 1996; 60: 41-7
    • (1996) Clin Pharmacol Ther , vol.60 , pp. 41-47
    • Linnet, K.1    Wiborg, O.2
  • 560
    • 0023611859 scopus 로고
    • Pharmacokinetics of pimozide in adults and children with Tourettes syndrome
    • Sallee RF, Pollock BG, Stiller RL, et al. Pharmacokinetics of pimozide in adults and children with Tourettes syndrome. J Clin Pharmacol 1987; 27: 776-81
    • (1987) J Clin Pharmacol , vol.27 , pp. 776-781
    • Sallee, R.F.1    Pollock, B.G.2    Stiller, R.L.3
  • 561
    • 0000280860 scopus 로고    scopus 로고
    • A metabolic interaction between clarithromycin and pimozide may result in cardiac toxicity
    • Flockhart DA, Richard E, Woosley RL, et al. A metabolic interaction between clarithromycin and pimozide may result in cardiac toxicity. Clin Pharmacol Ther 1996; 59: 189
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 189
    • Flockhart, D.A.1    Richard, E.2    Woosley, R.L.3
  • 562
    • 0027436269 scopus 로고    scopus 로고
    • Pharmacokinetics of the novel antipsychotic agent risperidone and the prolactin response in healthy subjects
    • Huang M-L, Van Peer A, Woestenborghs R, et al. Pharmacokinetics of the novel antipsychotic agent risperidone and the prolactin response in healthy subjects. Clin Pharmacol Ther 1996; 54: 257-68
    • (1996) Clin Pharmacol Ther , vol.54 , pp. 257-268
    • Huang, M.-L.1    Van Peer, A.2    Woestenborghs, R.3
  • 563
    • 0026086815 scopus 로고
    • Plasma levels of thioridazine and metabolites are influenced by the debrisoquin hydroxylation phenotype
    • von Bahr C, Movin G, Nordin C, et al. Plasma levels of thioridazine and metabolites are influenced by the debrisoquin hydroxylation phenotype. Clin Pharmacol Ther 1991; 49: 234-40
    • (1991) Clin Pharmacol Ther , vol.49 , pp. 234-240
    • Von Bahr, C.1    Movin, G.2    Nordin, C.3
  • 564
    • 0029018089 scopus 로고
    • Metabolism of thioridazine by microsomal monooxygenases; relative roles of P450 and flavin-containing monooxygenase
    • Blake BL, Rose RL, Mailman RB, et al. Metabolism of thioridazine by microsomal monooxygenases; relative roles of P450 and flavin-containing monooxygenase. Xenobiotica 1995; 25: 377-93
    • (1995) Xenobiotica , vol.25 , pp. 377-393
    • Blake, B.L.1    Rose, R.L.2    Mailman, R.B.3
  • 565
    • 0029897864 scopus 로고    scopus 로고
    • Plasma levels of the enantiomers of thioridazine, thioridazine 2-sulfoxide, thioridazine 2-sulfone, and thioridazine 5-sulfoxide in poor and extensive metabolizers of dextromethorphan and mephenytoin
    • Eap CB, Guentert TW, Schäublin-Loidl M, et al. Plasma levels of the enantiomers of thioridazine, thioridazine 2-sulfoxide, thioridazine 2-sulfone, and thioridazine 5-sulfoxide in poor and extensive metabolizers of dextromethorphan and mephenytoin. Clin Pharmacol Ther 1996; 59: 322-31
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 322-331
    • Eap, C.B.1    Guentert, T.W.2    Schäublin-Loidl, M.3
  • 566
    • 0026451267 scopus 로고
    • Fluoxetine impairs clearance of alprazolam but not of clonazepam
    • Greenblatt DJ, Preskorn SH, Cotreau MM, et al. Fluoxetine impairs clearance of alprazolam but not of clonazepam. Clin Pharmacol Ther 1992; 52: 479-86
    • (1992) Clin Pharmacol Ther , vol.52 , pp. 479-486
    • Greenblatt, D.J.1    Preskorn, S.H.2    Cotreau, M.M.3
  • 567
    • 0027326229 scopus 로고
    • Alprazolam metabolism in vitro: Studies of man, monkey, mouse and rat liver microsomes
    • von Moltke LL, Greenblatt DJ, Harmatz JS, et al. Alprazolam metabolism in vitro: studies of man, monkey, mouse and rat liver microsomes. Pharmacology 1993; 47: 268-76
    • (1993) Pharmacology , vol.47 , pp. 268-276
    • Von Moltke, L.L.1    Greenblatt, D.J.2    Harmatz, J.S.3
  • 568
    • 0029984992 scopus 로고    scopus 로고
    • A kinetic and dynamic study of oral alprazolam with and without erythromycin in humans: In vivo evidence for the involvement of CYP3A4 in alprazolam metabolism
    • Yasui N, Koichi O, Kaneko S, et al. A kinetic and dynamic study of oral alprazolam with and without erythromycin in humans: In vivo evidence for the involvement of CYP3A4 in alprazolam metabolism. Clin Pharmacol Ther 1996; 59: 514-9
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 514-519
    • Yasui, N.1    Koichi, O.2    Kaneko, S.3
  • 569
    • 0024402403 scopus 로고
    • Pharmacokinetics of the newer benzodiazepines
    • Garzone PD, Kroboth PD. Pharmacokinetics of the newer benzodiazepines. Clin Pharmacokinet 1989; 16: 337-64
    • (1989) Clin Pharmacokinet , vol.16 , pp. 337-364
    • Garzone, P.D.1    Kroboth, P.D.2
  • 570
    • 0028279667 scopus 로고
    • Inhibitors of alprazolam metabolism in vitro: Effect of serotonin-reuptake-inhibitor antidepressants, ketoconazole and quinidine
    • von Moltke LL, Greenblatt DJ, Cotreau-Bibbo MM, et al. Inhibitors of alprazolam metabolism in vitro: effect of serotonin-reuptake-inhibitor antidepressants, ketoconazole and quinidine. Br J Clin Pharmacol 1994; 38: 23-31
    • (1994) Br J Clin Pharmacol , vol.38 , pp. 23-31
    • Von Moltke, L.L.1    Greenblatt, D.J.2    Cotreau-Bibbo, M.M.3
  • 571
    • 0025179699 scopus 로고
    • In vitro metabolism of the antianxiety drug buspirone as a predictor of its metabolism in vivo
    • Jajoo HK, Blair IA, Klunk LJ, et al. In vitro metabolism of the antianxiety drug buspirone as a predictor of its metabolism in vivo. Xenobiotica 1990; 20: 779-86
    • (1990) Xenobiotica , vol.20 , pp. 779-786
    • Jajoo, H.K.1    Blair, I.A.2    Klunk, L.J.3
  • 572
    • 0017375527 scopus 로고
    • Clinical pharmacokinetics of hypnotics
    • Breimer DD. Clinical pharmacokinetics of hypnotics. Clin Pharmacokinet 1977; 2: 93-109
    • (1977) Clin Pharmacokinet , vol.2 , pp. 93-109
    • Breimer, D.D.1
  • 573
    • 0027468597 scopus 로고
    • Identification of the human and animal hepatic cytochromes P450 involved in clonazepam metabolism
    • Seree EJ, Pisano PJ, Placidi M, et al. Identification of the human and animal hepatic cytochromes P450 involved in clonazepam metabolism. Fundam Clin Pharmacol 1993; 7: 69-75
    • (1993) Fundam Clin Pharmacol , vol.7 , pp. 69-75
    • Seree, E.J.1    Pisano, P.J.2    Placidi, M.3
  • 574
    • 0018332470 scopus 로고
    • Pharmacokinetics of clorazepate in pregnant and nonpregnant women
    • Rey E, dAthis P, Giraux P, et al. Pharmacokinetics of clorazepate in pregnant and nonpregnant women. Eur J Clin Pharmacol 1979; 15: 175-80
    • (1979) Eur J Clin Pharmacol , vol.15 , pp. 175-180
    • Rey, E.1    DAthis, P.2    Giraux, P.3
  • 575
    • 0024246519 scopus 로고
    • Desmethyldiazepam pharmacokinetics: Studies following intravenous and oral desmethyldiazepam, oral clorazepate, and intravenous diazepam
    • Greenblatt DJ, Divoll MK, Soong MH, et al. Desmethyldiazepam pharmacokinetics: studies following intravenous and oral desmethyldiazepam, oral clorazepate, and intravenous diazepam. J Clin Pharmacol 1988; 28: 853-9
    • (1988) J Clin Pharmacol , vol.28 , pp. 853-859
    • Greenblatt, D.J.1    Divoll, M.K.2    Soong, M.H.3
  • 576
    • 0024580554 scopus 로고
    • Importance of genetic factors in the regulation of diazepam metabolism: Relationship to 5-mephenytoin, but not debrisoquin, hydroxylation phenotype
    • Bertilsson L, Henthorn TK, Sanch E, et al. Importance of genetic factors in the regulation of diazepam metabolism: Relationship to 5-mephenytoin, but not debrisoquin, hydroxylation phenotype. Clin Pharmacol Ther 1989; 45: 348-55
    • (1989) Clin Pharmacol Ther , vol.45 , pp. 348-355
    • Bertilsson, L.1    Henthorn, T.K.2    Sanch, E.3
  • 577
    • 0028080304 scopus 로고
    • Inhibition of diazepam metabolism by fluvoxamine: A pharmacokinetic study in normal volunteers
    • Perucca E, Gatti G, Cipolla G, et al. Inhibition of diazepam metabolism by fluvoxamine: a pharmacokinetic study in normal volunteers. Clin Pharmacol Ther 1994; 56: 471-6
    • (1994) Clin Pharmacol Ther , vol.56 , pp. 471-476
    • Perucca, E.1    Gatti, G.2    Cipolla, G.3
  • 578
    • 0028589604 scopus 로고
    • m diazepam N-demethylase in livers of poor metabolizers for 5-mephenytoin 4-hydroxylation
    • m diazepam N-demethylase in livers of poor metabolizers for 5-mephenytoin 4-hydroxylation. Pharmacogenetics 1994; 4: 323-31
    • (1994) Pharmacogenetics , vol.4 , pp. 323-331
    • Yasumori, T.1    Qing-Hua, L.2    Yamazoe, Y.3
  • 579
    • 0030049943 scopus 로고    scopus 로고
    • Interaction between erythromycin and the benzodiazepines diazepam and flunitrazepam
    • Luurila H, Olkkola KT, Neuvonen PJ. Interaction between erythromycin and the benzodiazepines diazepam and flunitrazepam. Pharmacol Toxicol 1996; 78: 117-22
    • (1996) Pharmacol Toxicol , vol.78 , pp. 117-122
    • Luurila, H.1    Olkkola, K.T.2    Neuvonen, P.J.3
  • 580
  • 581
    • 0021863799 scopus 로고
    • Kinetic and pharmacological studies on estazolam in mice and man
    • Mancinelli A, Guiso G, Garattini S, et al. Kinetic and pharmacological studies on estazolam in mice and man. Xenobiotica 1985; 15: 257-65
    • (1985) Xenobiotica , vol.15 , pp. 257-265
    • Mancinelli, A.1    Guiso, G.2    Garattini, S.3
  • 582
    • 0019624375 scopus 로고
    • Kinetics and clinical effects of flurazepam in young and elderly noninsomniacs
    • Greenblatt DJ, Divoll M, Harmatz JS, et al. Kinetics and clinical effects of flurazepam in young and elderly noninsomniacs. Clin Pharmacol Ther 1981; 30: 475-86
    • (1981) Clin Pharmacol Ther , vol.30 , pp. 475-486
    • Greenblatt, D.J.1    Divoll, M.2    Harmatz, J.S.3
  • 583
    • 0019819202 scopus 로고
    • Clinical pharmacokinetics of oxazepam and lorazepam
    • Greenblatt DJ. Clinical pharmacokinetics of oxazepam and lorazepam. Clin Pharmacokinet 1981; 6: 89-105
    • (1981) Clin Pharmacokinet , vol.6 , pp. 89-105
    • Greenblatt, D.J.1
  • 584
    • 0028923920 scopus 로고
    • Early pharmacokinetics of midazolam: Sampling site and schedule considerations
    • Mastey V, Donati F, Varin F. Early pharmacokinetics of midazolam: Sampling site and schedule considerations. Clin Pharmacokinet 1995; 9: 131-40
    • (1995) Clin Pharmacokinet , vol.9 , pp. 131-140
    • Mastey, V.1    Donati, F.2    Varin, F.3
  • 585
    • 0027477751 scopus 로고
    • A potentially hazardous interaction between erythiomycin and midazolam
    • Olkkola KT, Aranko K, Luurila H, et al. A potentially hazardous interaction between erythiomycin and midazolam. Clin Pharmacol Ther 1993; 53: 298-305
    • (1993) Clin Pharmacol Ther , vol.53 , pp. 298-305
    • Olkkola, K.T.1    Aranko, K.2    Luurila, H.3
  • 586
  • 587
    • 0030015297 scopus 로고    scopus 로고
    • Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism
    • Thummel KE, OShea D, Paine MF, et al. Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism. Clin Pharmacol Ther 1996; 59: 491-502
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 491-502
    • Thummel, K.E.1    Oshea, D.2    Paine, M.F.3
  • 588
    • 0024373348 scopus 로고
    • Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4
    • Kronbach T, Mathys D, Umeno M, et al. Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4. Mol Pharmacol 1989; 36: 89-96
    • (1989) Mol Pharmacol , vol.36 , pp. 89-96
    • Kronbach, T.1    Mathys, D.2    Umeno, M.3
  • 589
    • 0029664974 scopus 로고    scopus 로고
    • The effect of systemic antimycotics, itraconazole and fluconazole, on the pharmacokinetics and pharmacodynamics of intravenous and oral midazolam
    • Olkkola KT, Ahonen J, Neuvonen PJ. The effect of systemic antimycotics, itraconazole and fluconazole, on the pharmacokinetics and pharmacodynamics of intravenous and oral midazolam. Anesth Analg 1996; 82: 511-6
    • (1996) Anesth Analg , vol.82 , pp. 511-516
    • Olkkola, K.T.1    Ahonen, J.2    Neuvonen, P.J.3
  • 590
    • 0028811175 scopus 로고
    • Interindividual variability in the glucuronidation of (S) oxazepam contrasted with that of (R) oxazepam
    • Patel M, Tang BK, Grant DM, et al. Interindividual variability in the glucuronidation of (S) oxazepam contrasted with that of (R) oxazepam. Pharmacogenetics 1995; 5: 287-97
    • (1995) Pharmacogenetics , vol.5 , pp. 287-297
    • Patel, M.1    Tang, B.K.2    Grant, D.M.3
  • 592
    • 0029089659 scopus 로고
    • Glucuronidation of propofol in microsomal fractions from various tissues and species including humans: Effect of different drugs
    • Le Guellec C, Lacarelle B, Villard P-H, et al. Glucuronidation of propofol in microsomal fractions from various tissues and species including humans: Effect of different drugs. Anesth Analg 1995; 81: 855-61
    • (1995) Anesth Analg , vol.81 , pp. 855-861
    • Le Guellec, C.1    Lacarelle, B.2    Villard, P.-H.3
  • 593
    • 0029878797 scopus 로고    scopus 로고
    • Lack of effect of antimycotic itraconazole on the pharmacokinetics or pharmacodynamics of temazepam
    • Ahonen J, Olkkola KT, Neuvonen PJ. Lack of effect of antimycotic itraconazole on the pharmacokinetics or pharmacodynamics of temazepam. Ther Drug Monitor 1996; 18: 124-7
    • (1996) Ther Drug Monitor , vol.18 , pp. 124-127
    • Ahonen, J.1    Olkkola, K.T.2    Neuvonen, P.J.3
  • 594
    • 0030077245 scopus 로고    scopus 로고
    • Triazolam biotransformation by human liver microsomes in vitro: Effects of metabolic inhibitors and clinical confirmation of a predicted interaction with kelaconazole
    • von Moltke LL, Greenblatt DJ, Harmatz JS, et al. Triazolam biotransformation by human liver microsomes in vitro: effects of metabolic inhibitors and clinical confirmation of a predicted interaction with kelaconazole. J Pharmacol Exp Ther 1996; 276: 370-9
    • (1996) J Pharmacol Exp Ther , vol.276 , pp. 370-379
    • Von Moltke, L.L.1    Greenblatt, D.J.2    Harmatz, J.S.3
  • 595
    • 0029101508 scopus 로고
    • Plasma concentrations of triazolam are increase by concomitant ingestion of grapefruit juice
    • Hukkinen SK, Varhe A, Olkkola KT, et al. Plasma concentrations of triazolam are increase by concomitant ingestion of grapefruit juice. Clin Pharmacol Ther 1995; 58: 127-31
    • (1995) Clin Pharmacol Ther , vol.58 , pp. 127-131
    • Hukkinen, S.K.1    Varhe, A.2    Olkkola, K.T.3
  • 596
    • 0030025732 scopus 로고    scopus 로고
    • Triazolam pharmacokinetics and pharmacodynamics in Caucasians and southern asians: Ethnicity and CYP3 a activity
    • Kinirons MT, Lang CC, He HB, et al. Triazolam pharmacokinetics and pharmacodynamics in Caucasians and southern asians: ethnicity and CYP3 A activity. Br J Clin Pharmacol 1996; 41: 69-72
    • (1996) Br J Clin Pharmacol , vol.41 , pp. 69-72
    • Kinirons, M.T.1    Lang, C.C.2    He, H.B.3
  • 597
    • 0023009594 scopus 로고
    • A pharmacokinetic interaction between erythromycin and triazolam
    • Phillips JP, Antal EJ, Smith RB. A pharmacokinetic interaction between erythromycin and triazolam. J Clin Psychopharmacol 1986; 6: 297-9
    • (1986) J Clin Psychopharmacol , vol.6 , pp. 297-299
    • Phillips, J.P.1    Antal, E.J.2    Smith, R.B.3
  • 598
    • 0028787788 scopus 로고
    • Oxidative metabolism of zolpidem by human liver cytochrome P450S
    • Pichard L, Gillet G, Bonfils C, et al. Oxidative metabolism of zolpidem by human liver cytochrome P450S. Drug Metab Dispos 1995; 23: 1253-62
    • (1995) Drug Metab Dispos , vol.23 , pp. 1253-1262
    • Pichard, L.1    Gillet, G.2    Bonfils, C.3
  • 599
    • 0029074925 scopus 로고
    • Clinical pharmacokinetics and pharmacodynamics of zolpidem: Therapeutic implications
    • Salvà P, Costa J. Clinical pharmacokinetics and pharmacodynamics of zolpidem: therapeutic implications. Clin Pharmacokinet 1995; 29: 142-53
    • (1995) Clin Pharmacokinet , vol.29 , pp. 142-153
    • Salvà, P.1    Costa, J.2
  • 600
    • 0030435332 scopus 로고    scopus 로고
    • Dexamethasone metabolism by human liver in vitro. Metabolite identification and inhibition of 6-hydroxylation
    • Gentile DM, Tomlinson ES, Maggs JL, et al. Dexamethasone metabolism by human liver in vitro. Metabolite identification and inhibition of 6-hydroxylation. J Pharmacol Exp Ther 1996; 277: 105-12
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 105-112
    • Gentile, D.M.1    Tomlinson, E.S.2    Maggs, J.L.3
  • 601
    • 0030059885 scopus 로고    scopus 로고
    • Identification of a novel dexamethasone responsive enhancer in the human CYP3A5 gene and its activation in human and rat liver cells
    • Schuetz JD, Schuetz EG, Thottassery JV, et al. Identification of a novel dexamethasone responsive enhancer in the human CYP3A5 gene and its activation in human and rat liver cells. Mol Pharmacol 1996; 49: 63-72
    • (1996) Mol Pharmacol , vol.49 , pp. 63-72
    • Schuetz, J.D.1    Schuetz, E.G.2    Thottassery, J.V.3
  • 602
    • 0025368334 scopus 로고
    • Pharmacokinetic drug interactions with oral contraceptives
    • Back DJ, Orme MLE. Pharmacokinetic drug interactions with oral contraceptives. Clin Pharmacokinet 1990; 18: 472-84
    • (1990) Clin Pharmacokinet , vol.18 , pp. 472-484
    • Back, D.J.1    Orme, M.L.E.2
  • 603
    • 0029098973 scopus 로고
    • Pharmacokinetic and pharmacologic variation between different estrogen products
    • OConnell MB. Pharmacokinetic and pharmacologic variation between different estrogen products. J Clin Pharmacol 1995; 35: 18S-24S
    • (1995) J Clin Pharmacol , vol.35
    • Oconnell, M.B.1
  • 604
    • 0028792438 scopus 로고
    • Flavonoids in grapefruit juice inhibit the in vitro hepatic metabolism of 17β-estradiol
    • Schubert W, Eriksson U, Edgar B, et al. Flavonoids in grapefruit juice inhibit the in vitro hepatic metabolism of 17β-estradiol. Eur J Drug Metab Pharmacokinet 1995, 20: 219-24
    • (1995) Eur J Drug Metab Pharmacokinet , vol.20 , pp. 219-224
    • Schubert, W.1    Eriksson, U.2    Edgar, B.3
  • 605
    • 0023883363 scopus 로고
    • Oxidation of 17-α-ethynylestradiol by human liver cytochrome P-450
    • Guengerich FP. Oxidation of 17-α-ethynylestradiol by human liver cytochrome P-450. Mol Pharmacol 1988; 33: 500-8
    • (1988) Mol Pharmacol , vol.33 , pp. 500-508
    • Guengerich, F.P.1
  • 606
    • 0027521059 scopus 로고
    • Human bilirubin UDP-glucuronosyltransferase catalyzes the glucuronidation of ethinylestradiol
    • Ebner T, Remmel R, Burchell B. Human bilirubin UDP-glucuronosyltransferase catalyzes the glucuronidation of ethinylestradiol. Mol Pharmacol 1993; 43: 649-54
    • (1993) Mol Pharmacol , vol.43 , pp. 649-654
    • Ebner, T.1    Remmel, R.2    Burchell, B.3
  • 607
    • 0025637609 scopus 로고
    • Pharmacokinetics of ethinyl estradiol and mestranol
    • Goldhzieher JW, Brody SA. Pharmacokinetics of ethinyl estradiol and mestranol. Am J Obstet Gynecol 1990; 163: 2114-9
    • (1990) Am J Obstet Gynecol , vol.163 , pp. 2114-2119
    • Goldhzieher, J.W.1    Brody, S.A.2
  • 608
    • 0028824848 scopus 로고
    • Identification of human cytochrome P450 isozymes responsible for the in vitro oxidative metabolism of finasteride
    • Huskey S-EW, Dean DC, Miller RR, et al. Identification of human cytochrome P450 isozymes responsible for the in vitro oxidative metabolism of finasteride. Drug Metab Dispos 1995; 23: 1126-35
    • (1995) Drug Metab Dispos , vol.23 , pp. 1126-1135
    • Huskey, S.-E.W.1    Dean, D.C.2    Miller, R.R.3
  • 609
    • 0030040505 scopus 로고    scopus 로고
    • Clinical pharmacokinetics and pharmacodynamics of finasteride
    • Steiner JF. Clinical pharmacokinetics and pharmacodynamics of finasteride. Clin Pharmacokinet 1996; 30: 16-27
    • (1996) Clin Pharmacokinet , vol.30 , pp. 16-27
    • Steiner, J.F.1
  • 610
    • 0027373878 scopus 로고
    • Metabolic activation of the nitroaminic antiandrogen flutamide by rat and human cytochromes P-450, including forms belonging to the 3A and 1A subfamilies
    • Berson A, Wolf C, Chachaty C, et al. Metabolic activation of the nitroaminic antiandrogen flutamide by rat and human cytochromes P-450, including forms belonging to the 3A and 1A subfamilies. J Pharmacol Exp Ther 1993; 265: 366-72
    • (1993) J Pharmacol Exp Ther , vol.265 , pp. 366-372
    • Berson, A.1    Wolf, C.2    Chachaty, C.3
  • 611
    • 0028925148 scopus 로고
    • Levonorgestrel: Clinical pharmacokinetics
    • Fotherby K. Levonorgestrel: Clinical pharmacokinetics. Clin Pharmacokinet 1995; 28: 203-15
    • (1995) Clin Pharmacokinet , vol.28 , pp. 203-215
    • Fotherby, K.1
  • 612
    • 0029101172 scopus 로고
    • P450-mediated progesterone hydroxylation in Cochliobolus lunatus
    • Vitas M, Rozman D, Komel R, et al. P450-mediated progesterone hydroxylation in Cochliobolus lunatus. J Biotech 1995; 42: 145-50
    • (1995) J Biotech , vol.42 , pp. 145-150
    • Vitas, M.1    Rozman, D.2    Komel, R.3
  • 613
    • 0023803235 scopus 로고
    • Pharmacokinetics and metabolism of medroxyprogesterone acetate in patients with advanced breast cancer
    • Utaaker E, Lundgren S, Kvinnsland S, et al. Pharmacokinetics and metabolism of medroxyprogesterone acetate in patients with advanced breast cancer. J Steroid Biochem 1988; 31: 437-41
    • (1988) J Steroid Biochem , vol.31 , pp. 437-441
    • Utaaker, E.1    Lundgren, S.2    Kvinnsland, S.3
  • 614
    • 0019827363 scopus 로고
    • Medroxyprogesterone acetate in human serum
    • Marthrubutham M, Fotherby K. Medroxyprogesterone acetate in human serum. J Steroid Biochem 1981; 14: 783-6
    • (1981) J Steroid Biochem , vol.14 , pp. 783-786
    • Marthrubutham, M.1    Fotherby, K.2
  • 615
    • 0026585136 scopus 로고
    • Clinical pharmacokinetics of endocrine agents used in advanced breast cancer
    • Lonning PE, Lien EA, Lundgren S, et al. Clinical pharmacokinetics of endocrine agents used in advanced breast cancer. Clin Pharmacokinet 1992; 22: 327-58
    • (1992) Clin Pharmacokinet , vol.22 , pp. 327-358
    • Lonning, P.E.1    Lien, E.A.2    Lundgren, S.3
  • 616
    • 0026572562 scopus 로고
    • Megestrol acetate reverses multidrug resistance and interacts with P-glycoprotein
    • Fleming GF, Amato JM, Agresti M, et al. Megestrol acetate reverses multidrug resistance and interacts with P-glycoprotein. Cancer Chemother Pharmacol 1992; 29: 445-9
    • (1992) Cancer Chemother Pharmacol , vol.29 , pp. 445-449
    • Fleming, G.F.1    Amato, J.M.2    Agresti, M.3
  • 617
    • 0029019018 scopus 로고
    • Pharmacokinetic evaluation of two different formulations of megestrol acetate in patients with advanced malignancies
    • Camaggi CM, Strocchi E, Martoni A, et al. Pharmacokinetic evaluation of two different formulations of megestrol acetate in patients with advanced malignancies. Cancer Chemother Pharmacol 1995; 36: 356-9
    • (1995) Cancer Chemother Pharmacol , vol.36 , pp. 356-359
    • Camaggi, C.M.1    Strocchi, E.2    Martoni, A.3
  • 618
    • 0027365895 scopus 로고
    • Gender-based effects on methylprednisolone pharmacokinetics and pharmacodynamics
    • Lew KH, Ludwig EA, Milad MA, et al. Gender-based effects on methylprednisolone pharmacokinetics and pharmacodynamics. Clin Pharmacol Ther 1993; 54: 402-14
    • (1993) Clin Pharmacol Ther , vol.54 , pp. 402-414
    • Lew, K.H.1    Ludwig, E.A.2    Milad, M.A.3
  • 619
    • 0029880041 scopus 로고    scopus 로고
    • The effects of menopause and hormone replacement therapies on pre-dnisolone and erythromycin pharmacokinetics
    • Harris RZ, Tsunoda SM, Mroczkowski P, et al. The effects of menopause and hormone replacement therapies on pre-dnisolone and erythromycin pharmacokinetics. Clin Pharmacol Ther 1996; 59: 429-35
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 429-435
    • Harris, R.Z.1    Tsunoda, S.M.2    Mroczkowski, P.3
  • 620
    • 0028878830 scopus 로고
    • Budesonide is metabolized by cytochrome P450 3A (CYP3A) enzymes in human liver
    • Jönsson G, Aström A, Andersson P. Budesonide is metabolized by cytochrome P450 3A (CYP3A) enzymes in human liver. Drug Metab Dispos 1995; 23: 137-42
    • (1995) Drug Metab Dispos , vol.23 , pp. 137-142
    • Jönsson, G.1    Aström, A.2    Andersson, P.3
  • 621
    • 0025302890 scopus 로고
    • Clinical pharmacokinetics of prednisone and prednisolone
    • Frey BM, Frey FJ. Clinical pharmacokinetics of prednisone and prednisolone. Clin Pharmacokinet 1990; 19: 126-46
    • (1990) Clin Pharmacokinet , vol.19 , pp. 126-146
    • Frey, B.M.1    Frey, F.J.2
  • 622
    • 0024412071 scopus 로고
    • Cytochrome P450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine
    • Aoyama T, Yamano S, Waxman DJ, et al. Cytochrome P450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine. J Biol Chem 1989; 264: 10388-95
    • (1989) J Biol Chem , vol.264 , pp. 10388-10395
    • Aoyama, T.1    Yamano, S.2    Waxman, D.J.3
  • 623
    • 0025090954 scopus 로고
    • Pharmacokinetics and neuromuscular blocking effects of atracurium besylate and two of its metabolites in patients with normal and impaired renal function
    • Vandenbrom RHG, Wierda JMKH, Agoston S. Pharmacokinetics and neuromuscular blocking effects of atracurium besylate and two of its metabolites in patients with normal and impaired renal function. Clin Pharmacokinet 1990; 19: 230-40
    • (1990) Clin Pharmacokinet , vol.19 , pp. 230-240
    • Vandenbrom, R.H.G.1    Wierda, J.M.K.H.2    Agoston, S.3
  • 625
    • 0028227627 scopus 로고
    • Clinical enflurane metabolism by cytochrome P450 2E1
    • Kharasch ED, Thummel KE, Mautz D, et al. Clinical enflurane metabolism by cytochrome P450 2E1. Clin Pharmacol Ther 1994; 55: 434-40
    • (1994) Clin Pharmacol Ther , vol.55 , pp. 434-440
    • Kharasch, E.D.1    Thummel, K.E.2    Mautz, D.3
  • 626
    • 0029609131 scopus 로고
    • Stereoselective metabolism of enflurane by human liver cytochrome P450 2E1
    • Garton KJ, Yuen P, Meinwald J, et al. Stereoselective metabolism of enflurane by human liver cytochrome P450 2E1. Drug Metab Dispos 1995; 23: 1426-30
    • (1995) Drug Metab Dispos , vol.23 , pp. 1426-1430
    • Garton, K.J.1    Yuen, P.2    Meinwald, J.3
  • 627
    • 0027515708 scopus 로고
    • Identification of cytochrome P450 2El as the predominant enzyme catalyzing human liver microsomal defluorination of sevoflurane, isoflurane, and methoxyflurane
    • Kharasch ED, Thummel KE. Identification of cytochrome P450 2El as the predominant enzyme catalyzing human liver microsomal defluorination of sevoflurane, isoflurane, and methoxyflurane. Anesthesiology 1993; 79: 795-807
    • (1993) Anesthesiology , vol.79 , pp. 795-807
    • Kharasch, E.D.1    Thummel, K.E.2
  • 628
    • 0029070863 scopus 로고
    • Clinical sevoflurane metabolism and disposition: II. the role of cytochrome P450 2E1 in fluoride and hexafluoroisopropanol formation
    • Kharasch ED, Armstrong AS, Gunn K, et al. Clinical sevoflurane metabolism and disposition: II. The role of cytochrome P450 2E1 in fluoride and hexafluoroisopropanol formation. Anesthesiology 1995; 82: 1379-88
    • (1995) Anesthesiology , vol.82 , pp. 1379-1388
    • Kharasch, E.D.1    Armstrong, A.S.2    Gunn, K.3
  • 629
    • 0028921691 scopus 로고
    • Pharmacokinetic and pharmacodynamic studies of N-acetylcysteine, a potential chemopreventive agent during a phase I trial
    • Pendyala L, Creaven PJ. Pharmacokinetic and pharmacodynamic studies of N-acetylcysteine, a potential chemopreventive agent during a phase I trial. Cancer Epidemiol Biomarkers Prev 1995; 4: 245-51
    • (1995) Cancer Epidemiol Biomarkers Prev , vol.4 , pp. 245-251
    • Pendyala, L.1    Creaven, P.J.2
  • 631
    • 0023029295 scopus 로고
    • Pharmacokinetics of intravenous and oral salbutamol and its sulphate conjugate
    • Morgan DJ, Paull JD, Rchmond BH, et al. Pharmacokinetics of intravenous and oral salbutamol and its sulphate conjugate. Br J Clin Pharmacol 1986; 22: 587-93
    • (1986) Br J Clin Pharmacol , vol.22 , pp. 587-593
    • Morgan, D.J.1    Paull, J.D.2    Rchmond, B.H.3
  • 632
    • 0027197696 scopus 로고
    • Gender and age as factors in the inhibition of renal clearance of amantadine by quinine and quinidine
    • Gaudry SE, Sitar DS, Smyth DD, et al. Gender and age as factors in the inhibition of renal clearance of amantadine by quinine and quinidine. Clin Pharmacol Ther 1993; 54: 23-7
    • (1993) Clin Pharmacol Ther , vol.54 , pp. 23-27
    • Gaudry, S.E.1    Sitar, D.S.2    Smyth, D.D.3
  • 633
    • 0028912283 scopus 로고
    • Chronic tobacco smoking and gender as variables affecting amantadine disposition in healthy subjects
    • Wong LTY, Sitar DS, Aoki FY. Chronic tobacco smoking and gender as variables affecting amantadine disposition in healthy subjects. Br J Clin Pharmacol 1995; 39: 81-4
    • (1995) Br J Clin Pharmacol , vol.39 , pp. 81-84
    • Wong, L.T.Y.1    Sitar, D.S.2    Aoki, F.Y.3
  • 634
    • 0025761992 scopus 로고
    • CSF baclofen levels after intrathecal administration in severe spasticity
    • Sallerin-Caute B, Lazorthes Y, Monsarrat B, et al. CSF baclofen levels after intrathecal administration in severe spasticity. Eur J Clin Pharmacol 1991; 40: 363-5
    • (1991) Eur J Clin Pharmacol , vol.40 , pp. 363-365
    • Sallerin-Caute, B.1    Lazorthes, Y.2    Monsarrat, B.3
  • 635
    • 0028241592 scopus 로고
    • Caffeine metabolism by human hepatic cytochromes P450: Contributions of 1A2, 2E1 and 3A isoforms
    • Tassaneeyakul W, Birkett DJ, McManus ME, et al. Caffeine metabolism by human hepatic cytochromes P450: contributions of 1A2, 2E1 and 3A isoforms. Biochem Pharmacol 1994; 47: 1767-76
    • (1994) Biochem Pharmacol , vol.47 , pp. 1767-1776
    • Tassaneeyakul, W.1    Birkett, D.J.2    McManus, M.E.3
  • 636
    • 0029981725 scopus 로고    scopus 로고
    • The use of caffeine as a metabolic probe for human drug metabolizing enzymes
    • Miners JO, Birkett DJ. The use of caffeine as a metabolic probe for human drug metabolizing enzymes. Gen Pharmacol 1996; 27: 245-9
    • (1996) Gen Pharmacol , vol.27 , pp. 245-249
    • Miners, J.O.1    Birkett, D.J.2
  • 637
    • 0028214383 scopus 로고
    • Carisoprodol elimination in humans
    • Olsen H, Koppang E, Alvn G, et al. Carisoprodol elimination in humans. Ther Drug Monitor 1994; 16: 337-40
    • (1994) Ther Drug Monitor , vol.16 , pp. 337-340
    • Olsen, H.1    Koppang, E.2    Alvn, G.3
  • 638
    • 0029028932 scopus 로고
    • Geographical/interracial differences in polymorphic drug oxidation: Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19
    • Bertilsson L. Geographical/interracial differences in polymorphic drug oxidation: current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19. Clin Pharmacokinet 1995; 29: 192-209
    • (1995) Clin Pharmacokinet , vol.29 , pp. 192-209
    • Bertilsson, L.1
  • 639
    • 0029035739 scopus 로고
    • Interindividual variability of chlorzoxazone 6-hydroxylation in men and women and its relationship to CYP2E1 genetic polymorphisms
    • Kim RB, OShea D, Wilkinson GR. Interindividual variability of chlorzoxazone 6-hydroxylation in men and women and its relationship to CYP2E1 genetic polymorphisms. Clin Pharmacol Ther 1995; 57: 645-55
    • (1995) Clin Pharmacol Ther , vol.57 , pp. 645-655
    • Kim, R.B.1    Oshea, D.2    Wilkinson, G.R.3
  • 640
    • 0028997743 scopus 로고
    • Chloroxazone is metabolized by human liver CYP1A2 as well as by human CYP2E1
    • Ono S, Hatanaka T, Hotta H, et al. Chloroxazone is metabolized by human liver CYP1A2 as well as by human CYP2E1. Pharmacogeneties 1995; 1995: 143-50
    • (1995) Pharmacogeneties , vol.1995 , pp. 143-150
    • Ono, S.1    Hatanaka, T.2    Hotta, H.3
  • 641
    • 0028889870 scopus 로고
    • Epoetin alfa: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in nonrenal applications
    • Markham A, Bryson HM, Epoetin alfa: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in nonrenal applications. Drugs 1995; 49: 232-54
    • (1995) Drugs , vol.49 , pp. 232-254
    • Markham, A.1    Bryson, H.M.2
  • 642
    • 0026499920 scopus 로고
    • Characterization of the cytochrome P-450 gene family responsible for the W-dealkylation of the ergot alkaloid CQA 206-291 in humans
    • Ball SE, Maurer G, Zollinger M, et al. Characterization of the cytochrome P-450 gene family responsible for the W-dealkylation of the ergot alkaloid CQA 206-291 in humans. Drug Metab Dispos 1992; 20: 56-63
    • (1992) Drug Metab Dispos , vol.20 , pp. 56-63
    • Ball, S.E.1    Maurer, G.2    Zollinger, M.3
  • 643
    • 0028095629 scopus 로고
    • Assessment of liver metabolic function: Clinical implications
    • Brockmöller J, Roots I. Assessment of liver metabolic function: clinical implications. Clin Pharmacokinet 1994; 27: 216-48
    • (1994) Clin Pharmacokinet , vol.27 , pp. 216-248
    • Brockmöller, J.1    Roots, I.2
  • 644
    • 0029990040 scopus 로고    scopus 로고
    • Evidence that cytochrome P-4502E1 contributes to ethanol elimination at low doses: Effects of diallyl sulfide and 4-methyl pyrazole on ethanol elimination in the perfused rat liver
    • Matsumoto H, Matsubayashi K, Fukui Y. Evidence that cytochrome P-4502E1 contributes to ethanol elimination at low doses: Effects of diallyl sulfide and 4-methyl pyrazole on ethanol elimination in the perfused rat liver. Alcohol Clin Exp Res 1996; 20: 12A-16A
    • (1996) Alcohol Clin Exp Res , vol.20
    • Matsumoto, H.1    Matsubayashi, K.2    Fukui, Y.3
  • 645
    • 0030431698 scopus 로고    scopus 로고
    • Microsomal ethanol oxidizing system activity by human hepatic cytochrome P450s
    • Asai H, Imaoka S, Kuroki T, et al. Microsomal ethanol oxidizing system activity by human hepatic cytochrome P450s. J Pharmacol Exp Ther 1996; 277: 1004-9
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 1004-1009
    • Asai, H.1    Imaoka, S.2    Kuroki, T.3
  • 646
    • 0029117256 scopus 로고
    • Metabolism of oral 9-cis-retinoic acid in the human identification of 9-cis-retinoyl-β-glucuronide and 9-cis-4-oxo-retinoyl-β-glucuronide as urinary metabolites
    • Sass JO, Masgrau E, Saurat J-H, et al. Metabolism of oral 9-cis-retinoic acid in the human identification of 9-cis-retinoyl-β-glucuronide and 9-cis-4-oxo-retinoyl-β-glucuronide as urinary metabolites. Drug Metab Dispos 1995; 23: 887-91
    • (1995) Drug Metab Dispos , vol.23 , pp. 887-891
    • Sass, J.O.1    Masgrau, E.2    Saurat, J.-H.3
  • 647
    • 0028786006 scopus 로고
    • Inhibition of all-trans-retinoic acid metabolism by fluconazole in vitro and in patients with acute promyelocytic leukemia
    • Schwartz EL, Hallam S, Gallagher RE, et al. Inhibition of all-trans-retinoic acid metabolism by fluconazole in vitro and in patients with acute promyelocytic leukemia. Biochem Pharmacol 1995; 50: 923-8
    • (1995) Biochem Pharmacol , vol.50 , pp. 923-928
    • Schwartz, E.L.1    Hallam, S.2    Gallagher, R.E.3
  • 648
    • 0029918184 scopus 로고    scopus 로고
    • Metabolism of all-trans, 9-cis, and 13-cis isomers of retinal by purified isozymes of microsomal cytochrome P450 and mechanism-based inhibition of retinoid oxidation by citral
    • Raner GM, Vaz ADN, Coon MJ. Metabolism of all-trans, 9-cis, and 13-cis isomers of retinal by purified isozymes of microsomal cytochrome P450 and mechanism-based inhibition of retinoid oxidation by citral. Mol Pharmacol 1996; 49: 515-22
    • (1996) Mol Pharmacol , vol.49 , pp. 515-522
    • Raner, G.M.1    Vaz, A.D.N.2    Coon, M.J.3
  • 649
    • 0026684697 scopus 로고
    • Pharmacokinetics and therapeutic efficacy of retinoids in skin diseases
    • Larsen FG, Nielsen-Kudsk F, Jakobsen P, et al. Pharmacokinetics and therapeutic efficacy of retinoids in skin diseases. Clin Pharmacokinet 1992; 23: 42-61
    • (1992) Clin Pharmacokinet , vol.23 , pp. 42-61
    • Larsen, F.G.1    Nielsen-Kudsk, F.2    Jakobsen, P.3
  • 650
    • 0024586375 scopus 로고
    • Metabolism of retinol and retinoic acid by human liver cytochrome P450IIC8
    • Leo MA, Lasker JM, Raucy JL, et al. Metabolism of retinol and retinoic acid by human liver cytochrome P450IIC8. Arch Biochem Biophys 1989; 269: 305-12
    • (1989) Arch Biochem Biophys , vol.269 , pp. 305-312
    • Leo, M.A.1    Lasker, J.M.2    Raucy, J.L.3
  • 651
    • 0027249747 scopus 로고
    • Participation of P450 3A enzymes in rat hepatic microsomal retinoic acid 4-hydroxylation
    • Martini R, Murray M. Participation of P450 3A enzymes in rat hepatic microsomal retinoic acid 4-hydroxylation. Arch Biochem Biophys 1993; 303: 57-66
    • (1993) Arch Biochem Biophys , vol.303 , pp. 57-66
    • Martini, R.1    Murray, M.2
  • 652
    • 0021933729 scopus 로고
    • Melatonin is metabolized to N-acetyl serotonin and 6-hydroxymelatonin in man
    • Young IM, Leone RM, Francis P, et al. Melatonin is metabolized to N-acetyl serotonin and 6-hydroxymelatonin in man. J Clin Endocrinol Metab 1985; 60: 114-9
    • (1985) J Clin Endocrinol Metab , vol.60 , pp. 114-119
    • Young, I.M.1    Leone, R.M.2    Francis, P.3
  • 653
    • 0023193395 scopus 로고
    • A cyclic isomer of 2-hydroxymelatonin: A novel metabolite of melatonin
    • Vakkuri O, Tervo J, Luttinen R, et al. A cyclic isomer of 2-hydroxymelatonin: A novel metabolite of melatonin. Endocrinology 1987; 120: 2453-9
    • (1987) Endocrinology , vol.120 , pp. 2453-2459
    • Vakkuri, O.1    Tervo, J.2    Luttinen, R.3
  • 654
    • 0025253595 scopus 로고
    • Pharmacokinetics of melatonin in man after intravenous infusion and bolus injection
    • Mallo C, Zaidan R, Galy G, et al. Pharmacokinetics of melatonin in man after intravenous infusion and bolus injection. Eur J Clin Pharmacol 1990; 38: 297-301
    • (1990) Eur J Clin Pharmacol , vol.38 , pp. 297-301
    • Mallo, C.1    Zaidan, R.2    Galy, G.3
  • 655
    • 0029113117 scopus 로고
    • In vitro-in vivo correlations of human (S)-nicotine metabolism
    • Berkman C, Park SB, Wrighton SA, et al. In vitro-in vivo correlations of human (S)-nicotine metabolism. Biochem Pharmacol 1995; 50: 565-70
    • (1995) Biochem Pharmacol , vol.50 , pp. 565-570
    • Berkman, C.1    Park, S.B.2    Wrighton, S.A.3
  • 656
    • 0027958225 scopus 로고
    • Nicotine metabolic profile in man: Comparison of cigarette smoking and transdermal nicotine
    • Benowitz NL, Jacob III P, Fong I, et al. Nicotine metabolic profile in man: Comparison of cigarette smoking and transdermal nicotine. J Pharmacol Exp Ther 1994; 268: 296-303
    • (1994) J Pharmacol Exp Ther , vol.268 , pp. 296-303
    • Benowitz, N.L.1    Jacob III, P.2    Fong, I.3
  • 657
    • 5544281923 scopus 로고    scopus 로고
    • Characterization of CYP2A6 involved in the 3-hydroxylation of cotinine in human liver microsomes
    • Nakajima M, Yamamoto T, Nunoya K-I, et al. Characterization of CYP2A6 involved in the 3-hydroxylation of cotinine in human liver microsomes. J Pharm Exp Ther 1996; 277: 1010-5
    • (1996) J Pharm Exp Ther , vol.277 , pp. 1010-1015
    • Nakajima, M.1    Yamamoto, T.2    Nunoya, K.-I.3
  • 658
    • 0025215045 scopus 로고
    • Pharmacokinetics of intravenous and oral pentoxifylline in healthy volunteers and in cirrhotic patients
    • Rames A, Poirier J-M, LeCoz F, et al. Pharmacokinetics of intravenous and oral pentoxifylline in healthy volunteers and in cirrhotic patients. Clin Pharmacol Ther 1990; 47: 354-9
    • (1990) Clin Pharmacol Ther , vol.47 , pp. 354-359
    • Rames, A.1    Poirier, J.-M.2    LeCoz, F.3
  • 659
    • 0025845805 scopus 로고
    • Prohenecid pharmacokinetics in cystic fibrosis
    • Weber A, de Groot R, Ramsey B, et al. Prohenecid pharmacokinetics in cystic fibrosis. Dev Pharmacol Ther 1991; 16: 7-12
    • (1991) Dev Pharmacol Ther , vol.16 , pp. 7-12
    • Weber, A.1    De Groot, R.2    Ramsey, B.3
  • 660
    • 0028170962 scopus 로고
    • Sumatriptan. Clinical pharmacokinetics
    • Scott AK. Sumatriptan. Clinical pharmacokinetics. Clin Pharmacokinet 1994; 27: 337-44
    • (1994) Clin Pharmacokinet , vol.27 , pp. 337-344
    • Scott, A.K.1
  • 661
    • 0028240611 scopus 로고
    • The effect of enzyme inhibition on the metabolism and activation of tacrine by human liver microsomes
    • Spaldin V, Madden S, Pool WF, et al. The effect of enzyme inhibition on the metabolism and activation of tacrine by human liver microsomes. Br J Clin Pharmacol 1994; 38: 15-22
    • (1994) Br J Clin Pharmacol , vol.38 , pp. 15-22
    • Spaldin, V.1    Madden, S.2    Pool, W.F.3
  • 662
    • 0029089652 scopus 로고
    • Determination of human hepatic cytochrome P4501A2 activity in vitro use of tacrine as an isoenzyme-specific probe
    • Spaldin V, Madden S, Adams DA, et al. Determination of human hepatic cytochrome P4501A2 activity in vitro use of tacrine as an isoenzyme-specific probe. Drug Metab Dispos 1995; 23: 929-34
    • (1995) Drug Metab Dispos , vol.23 , pp. 929-934
    • Spaldin, V.1    Madden, S.2    Adams, D.A.3
  • 664
    • 0028879821 scopus 로고
    • Thalidomide-induced neuropathy and genetic differences in drug metabolism
    • Harland CC, Steventon GB, Marsden JR. Thalidomide-induced neuropathy and genetic differences in drug metabolism. Eur J Clin Pharmacol 1995; 49: 1-6
    • (1995) Eur J Clin Pharmacol , vol.49 , pp. 1-6
    • Harland, C.C.1    Steventon, G.B.2    Marsden, J.R.3
  • 665
    • 0024402108 scopus 로고
    • Plasma pharmacokinetics and urinary excretion of thalidomide after oral dosing in healthy male volunteers
    • Chen T-L, Vogelsang GB, Petty BG, et al. Plasma pharmacokinetics and urinary excretion of thalidomide after oral dosing in healthy male volunteers. Drug Metab Dispos 1989; 17: 402-5
    • (1989) Drug Metab Dispos , vol.17 , pp. 402-405
    • Chen, T.-L.1    Vogelsang, G.B.2    Petty, B.G.3
  • 666
    • 0022625689 scopus 로고
    • Teratogen metabolism: Thalidomide activation is mediated by cytochrome P-450
    • Braun AG, Harding FA, Weinreb SL. Teratogen metabolism: Thalidomide activation is mediated by cytochrome P-450. Toxicol Appl Pharmacol 1986; 82: 175-9
    • (1986) Toxicol Appl Pharmacol , vol.82 , pp. 175-179
    • Braun, A.G.1    Harding, F.A.2    Weinreb, S.L.3
  • 667
    • 0028304159 scopus 로고
    • Stereoselectivity of the in vitro metabolism of thalidomide
    • Knoche B, Blaschke G. Stereoselectivity of the in vitro metabolism of thalidomide. Chirality 1994; 6: 221-4
    • (1994) Chirality , vol.6 , pp. 221-224
    • Knoche, B.1    Blaschke, G.2
  • 668
    • 0028927771 scopus 로고
    • Influence of endogenous and exogenous effectors on the pharmacokinetics of theophylline: Focus on biotransformation
    • Tröger U, Meyer FP. Influence of endogenous and exogenous effectors on the pharmacokinetics of theophylline: focus on biotransformation. Clin Pharmacokinet 1995; 28: 287-314
    • (1995) Clin Pharmacokinet , vol.28 , pp. 287-314
    • Tröger, U.1    Meyer, F.P.2
  • 669
    • 0028929645 scopus 로고
    • Metabolism of theophylline by cDNA-expressed human cytochromes P-450
    • Ha HR, Chen J, Freiburghaus AU, et al. Metabolism of theophylline by cDNA-expressed human cytochromes P-450. Br J Clin Pharmacol 1995; 39: 321-326
    • (1995) Br J Clin Pharmacol , vol.39 , pp. 321-326
    • Ha, H.R.1    Chen, J.2    Freiburghaus, A.U.3
  • 670
    • 0029018483 scopus 로고
    • Characterization of human cytochromes P450 involved in theophylline 8-hydroxylation
    • Zhang Z-Y, Kaminsky LS. Characterization of human cytochromes P450 involved in theophylline 8-hydroxylation. Biochem Pharmacol 1995; 50: 205-11
    • (1995) Biochem Pharmacol , vol.50 , pp. 205-211
    • Zhang, Z.-Y.1    Kaminsky, L.S.2
  • 671
    • 0030094638 scopus 로고    scopus 로고
    • Theophylline metabolism in human liver microsomes: Inhibition studies
    • Tjia JF, Colbert J, Back DJ. Theophylline metabolism in human liver microsomes: Inhibition studies. J Pharmacol Exp Ther 1996; 276: 912-7
    • (1996) J Pharmacol Exp Ther , vol.276 , pp. 912-917
    • Tjia, J.F.1    Colbert, J.2    Back, D.J.3
  • 672
    • 0028327671 scopus 로고
    • Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti-inflammatory drugs
    • Garcia Rodriguez LA, Jick H. Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti-inflammatory drugs. Lancet 1994; 343: 769-72
    • (1994) Lancet , vol.343 , pp. 769-772
    • Garcia Rodriguez, L.A.1    Jick, H.2
  • 673
    • 0028115856 scopus 로고
    • Torsade de pointes: Mechanisms and management
    • Napolitano C, Priori SG, Schwartz PJ. Torsade de pointes: mechanisms and management. Drugs 1994; 47: 51-65
    • (1994) Drugs , vol.47 , pp. 51-65
    • Napolitano, C.1    Priori, S.G.2    Schwartz, P.J.3
  • 674
    • 0030011760 scopus 로고    scopus 로고
    • Cardiac actions of antihistamines
    • Woosley RL. Cardiac actions of antihistamines. Ann Rev Pharmacol Toxicol 1996; 36: 233-52
    • (1996) Ann Rev Pharmacol Toxicol , vol.36 , pp. 233-252
    • Woosley, R.L.1
  • 675
    • 0029562495 scopus 로고
    • The emerging role of cytochrome P450 3A in psychopharmacology
    • Ketter TA, Flockhart DA, Post RM, et al. The emerging role of cytochrome P450 3A in psychopharmacology. J Clin Psychopharmacol 1995; 15: 387-98
    • (1995) J Clin Psychopharmacol , vol.15 , pp. 387-398
    • Ketter, T.A.1    Flockhart, D.A.2    Post, R.M.3
  • 676
    • 0028832177 scopus 로고
    • Cytochrome P450 monoxygenases and interactions of psychotropic drugs: A five year update
    • Shen WW. Cytochrome P450 monoxygenases and interactions of psychotropic drugs: a five year update. Int J Psychiatry Med 1995; 25: 277-90
    • (1995) Int J Psychiatry Med , vol.25 , pp. 277-290
    • Shen, W.W.1
  • 677
    • 0029979414 scopus 로고    scopus 로고
    • Polymorphic drug oxidation: Relevance to the treatment of psychiatric disorders
    • Bertilsson L, Dahl M-L. Polymorphic drug oxidation: relevance to the treatment of psychiatric disorders. CNS Drugs 1996; 5: 200-23
    • (1996) CNS Drugs , vol.5 , pp. 200-223
    • Bertilsson, L.1    Dahl, M.-L.2
  • 678
    • 0030003604 scopus 로고    scopus 로고
    • Psychiatry, psychopharmacology and P-450s
    • Glue P, Banfield C. Psychiatry, psychopharmacology and P-450s. Hum Psychopharmacol 1996; 11: 97-114
    • (1996) Hum Psychopharmacol , vol.11 , pp. 97-114
    • Glue, P.1    Banfield, C.2
  • 679
    • 0027383271 scopus 로고
    • The pharmacogenetics of the selective serotonin reuptake inhibitors
    • Brøsen K. The pharmacogenetics of the selective serotonin reuptake inhibitors. Clin Investig 1993; 71: 1002-9
    • (1993) Clin Investig , vol.71 , pp. 1002-1009
    • Brøsen, K.1
  • 680
    • 0029612315 scopus 로고
    • Interactions with drugs used in the treatment of depressive illness
    • DArcy PF, Griffin JP. Interactions with drugs used in the treatment of depressive illness. Adverse Drug React Toxicol Rev 1995; 14: 211-31
    • (1995) Adverse Drug React Toxicol Rev , vol.14 , pp. 211-231
    • Darcy, P.F.1    Griffin, J.P.2
  • 681
    • 0028926704 scopus 로고
    • Comparative pharmacokinetics of selective serotonin reuptake inhibitors: A look behind the mirror
    • Baumann P, Rochat B. Comparative pharmacokinetics of selective serotonin reuptake inhibitors: A look behind the mirror. Int Clin Psychopharmacol 1995; 10: 15-21
    • (1995) Int Clin Psychopharmacol , vol.10 , pp. 15-21
    • Baumann, P.1    Rochat, B.2


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