CYP3A4 inducible model for in vitro analysis of human drug metabolism using a bioartificial liver

Hepatology

Volumn 37, Issue 3, 2003, Pages 665-673

  Iwahori, Tohru ^a,b   Matsuura, Tomokazu ^a,b,d   Maehashi, Haruka ^a   Sugo, Ken ^a   Saito, Masaya ^a   Hosokawa, Masakiyo ^c   Chiba, Kan ^c   Masaki, Takahiro ^c   Aizaki, Hideki ^b   Ohkawa, Kiyoshi ^a   Suzuki, Tetsuro ^b  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^c CHIBA UNIVERSITY   (Japan)

^d KANAGAWA CANCER CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 3A4; DRUG; HEPATOCYTE NUCLEAR FACTOR 4; MESSENGER RNA; PREGNANE X RECEPTOR; RETINOID X RECEPTOR; RIFAMPICIN; TESTOSTERONE;

ANALYTIC METHOD; ARTICLE; ARTIFICIAL LIVER; BIOREACTOR; CELL CULTURE; DRUG METABOLISM; ENZYME INDUCTION; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL CARCINOMA; MODEL; MONOLAYER CULTURE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; WESTERN BLOTTING;

EID: 0037370005     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2003.50094     Document Type: Article

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