-
2
-
-
0032507263
-
Probing the specificity of aminoglycoside-ribosomal RNA interactions with designed synthetic analogs
-
Alper PB, Hendrix M, Sears P & Wong C-H (1998) Probing the specificity of aminoglycoside-ribosomal RNA interactions with designed synthetic analogs. Journal of the American Chemical Society 120:1965-1978.
-
(1998)
Journal of the American Chemical Society
, vol.120
, pp. 1965-1978
-
-
Alper, P.B.1
Hendrix, M.2
Sears, P.3
Wong, C.-H.4
-
3
-
-
0034636984
-
NMR structure of the HIV-1 nucleocapsid protein bound to stem-loop SL2 of the psi-RNA packaging signal. Implications for genome recognition
-
Amarasinghe GK, De Guzman RN, Turner RB, Chancellor, KJ, Wu ZR & Summers MF (2000) NMR structure of the HIV-1 nucleocapsid protein bound to stem-loop SL2 of the psi-RNA packaging signal. Implications for genome recognition. Journal of Molecular Biology 301:491-511.
-
(2000)
Journal of Molecular Biology
, vol.301
, pp. 491-511
-
-
Amarasinghe, G.K.1
De Guzman, R.N.2
Turner, R.B.3
Chancellor, K.J.4
Wu, Z.R.5
Summers, M.F.6
-
4
-
-
0035861980
-
Stem-loop SL4 of the HIV-1 psi RNA packaging signal exhibits weak affinity for the nucleocapsid protein. Structural studies and implications for genome recognition
-
Amarasinghe GK, Zhou J, Miskimon M, Chancellor KJ, McDonald JA, Matthews AG, Miller RR, Rouse MD & Summers MF (2001) Stem-loop SL4 of the HIV-1 psi RNA packaging signal exhibits weak affinity for the nucleocapsid protein. structural studies and implications for genome recognition. Journal of Molecular Biology 314:961-970.
-
(2001)
Journal of Molecular Biology
, vol.314
, pp. 961-970
-
-
Amarasinghe, G.K.1
Zhou, J.2
Miskimon, M.3
Chancellor, K.J.4
McDonald, J.A.5
Matthews, A.G.6
Miller, R.R.7
Rouse, M.D.8
Summers, M.F.9
-
5
-
-
0031879544
-
Genes and spectrum: The theoretical limits
-
Amyes SG (1998) Genes and spectrum: the theoretical limits. Clinical Infectious Diseases 27(Suppl. 1):S21-S28.
-
(1998)
Clinical Infectious Diseases
, vol.27
, Issue.SUPPL. 1
-
-
Amyes, S.G.1
-
6
-
-
0029821897
-
Inhibition of human cytomegalovirus immediate-early gene expression by an antisense oligonucleotide complementary to immediate-early RNA
-
Anderson KP, Fox MC, Brown-Driver V, Martin MJ & Azad RF (1996) Inhibition of human cytomegalovirus immediate-early gene expression by an antisense oligonucleotide complementary to immediate-early RNA. Antimicrobial Agents & Chemotherapy 40:2004-2011.
-
(1996)
Antimicrobial Agents & Chemotherapy
, vol.40
, pp. 2004-2011
-
-
Anderson, K.P.1
Fox, M.C.2
Brown-Driver, V.3
Martin, M.J.4
Azad, R.F.5
-
7
-
-
0027170180
-
Poliovirus RNA synthesis utilizes an RNP complex formed around the 5′-end of viral RNA
-
Andino R, Rieckhof GE, Achacoso PL & Baltimore D (1993) Poliovirus RNA synthesis utilizes an RNP complex formed around the 5′-end of viral RNA. EMBO Journal 12:3587-3598.
-
(1993)
EMBO Journal
, vol.12
, pp. 3587-3598
-
-
Andino, R.1
Rieckhof, G.E.2
Achacoso, P.L.3
Baltimore, D.4
-
8
-
-
0027216834
-
Antiviral activity of a phosphorothioate oligonucleotide complementary to RNA of the human cytomegalovirus major immediate-early region
-
Azad RF, Driver VB, Tanaka K, Crooke RM & Anderson KP (1993) Antiviral activity of a phosphorothioate oligonucleotide complementary to RNA of the human cytomegalovirus major immediate-early region. Antimicrobial Agents & Chemotherapy 37:1945-1954.
-
(1993)
Antimicrobial Agents & Chemotherapy
, vol.37
, pp. 1945-1954
-
-
Azad, R.F.1
Driver, V.B.2
Tanaka, K.3
Crooke, R.M.4
Anderson, K.P.5
-
9
-
-
0029924327
-
The binding mode of drugs to the TAR RNA of HIV-1 studied by electric linear dichroism
-
Bailly C, Colson P, Houssier C & Hamy F (1996) The binding mode of drugs to the TAR RNA of HIV-1 studied by electric linear dichroism. Nucleic Acids Research 24:1460-1464.
-
(1996)
Nucleic Acids Research
, vol.24
, pp. 1460-1464
-
-
Bailly, C.1
Colson, P.2
Houssier, C.3
Hamy, F.4
-
10
-
-
0024299563
-
Gene therapy. Intracellular immunization
-
Baltimore D (1988) Gene therapy. Intracellular immunization. Nature 335:395-396.
-
(1988)
Nature
, vol.335
, pp. 395-396
-
-
Baltimore, D.1
-
11
-
-
0029837263
-
Assays for poliovirus polymerase, 3D(Pol), and authentic RNA replication in HeLa S10 extracts
-
Barton DJ, Morasco BJ & Flanegan JB (1996) Assays for poliovirus polymerase, 3D(Pol), and authentic RNA replication in HeLa S10 extracts. Methods of Enzymology 275:35-57.
-
(1996)
Methods of Enzymology
, vol.275
, pp. 35-57
-
-
Barton, D.J.1
Morasco, B.J.2
Flanegan, J.B.3
-
12
-
-
0029784592
-
α-Helix-RNA major groove recognition in an HIV-1 rev peptide-RRE RNA complex
-
Battiste JL, Mao H, Rao NS, Tan R, Muhandiram DR, Kay LE, Frankel AD & Williamson JR (1996) α-Helix-RNA major groove recognition in an HIV-1 rev peptide-RRE RNA complex. Science 273:1547-1551.
-
(1996)
Science
, vol.273
, pp. 1547-1551
-
-
Battiste, J.L.1
Mao, H.2
Rao, N.S.3
Tan, R.4
Muhandiram, D.R.5
Kay, L.E.6
Frankel, A.D.7
Williamson, J.R.8
-
13
-
-
0032004967
-
A good antisense molecule is hard to find
-
Branch AD (1998) A good antisense molecule is hard to find. Trends in Biochemical Sciences 23:45-50.
-
(1998)
Trends in Biochemical Sciences
, vol.23
, pp. 45-50
-
-
Branch, A.D.1
-
14
-
-
0033000084
-
Inhibition of translation of hepatitis C virus RNA by 2-modified antisense oligonucleotides
-
Brown-Driver V, Eto T, Lesnik E, Anderson KP & Hanecak RC (1999) Inhibition of translation of hepatitis C virus RNA by 2-modified antisense oligonucleotides. Antisense Nucleic Acid Drug Development 9:145-154.
-
(1999)
Antisense Nucleic Acid Drug Development
, vol.9
, pp. 145-154
-
-
Brown-Driver, V.1
Eto, T.2
Lesnik, E.3
Anderson, K.P.4
Hanecak, R.C.5
-
15
-
-
0036839458
-
Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference
-
Capodici J, Kariko K & Weissman D (2002) Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference. Journal of Immunology 169:5196-5201.
-
(2002)
Journal of Immunology
, vol.169
, pp. 5196-5201
-
-
Capodici, J.1
Kariko, K.2
Weissman, D.3
-
16
-
-
0030954877
-
Structure-based discovery of ligands targeted to the RNA double helix
-
Chen Q Shafer RH & Kuntz ID (1997) Structure-based discovery of ligands targeted to the RNA double helix. Biochemistry 36:11402-11407.
-
(1997)
Biochemistry
, vol.36
, pp. 11402-11407
-
-
Chen, Q.1
Shafer, R.H.2
Kuntz, I.D.3
-
17
-
-
0031042434
-
Targeting RNA decay with 2′,5′ oligoadenylate-antisense in respiratory syncytial virus-infected cells
-
Cirino NM, Li G, Xiao W, Torrence PF & Silverman RH (1997) Targeting RNA decay with 2′,5′ oligoadenylate-antisense in respiratory syncytial virus-infected cells. Proceedings of the National Academy of Sciences, USA 94:1937-1942.
-
(1997)
Proceedings of the National Academy of Sciences, USA
, vol.94
, pp. 1937-1942
-
-
Cirino, N.M.1
Li, G.2
Xiao, W.3
Torrence, P.F.4
Silverman, R.H.5
-
18
-
-
0036721314
-
Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference
-
Coburn GA & Cullen BR (2002) Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference. Journal of Virology 76:9225-9231.
-
(2002)
Journal of Virology
, vol.76
, pp. 9225-9231
-
-
Coburn, G.A.1
Cullen, B.R.2
-
19
-
-
0036237498
-
A conserved RNA structure within the HCV IRES eIF3-binding site
-
Collier AJ, Gallego J, Klinck R, Cole PT, Harris SJ, Harrison GP, Aboul-Ela F, Varani G & Walker S (2002) A conserved RNA structure within the HCV IRES eIF3-binding site. Nature Structural Biology 9:375-380.
-
(2002)
Nature Structural Biology
, vol.9
, pp. 375-380
-
-
Collier, A.J.1
Gallego, J.2
Klinck, R.3
Cole, P.T.4
Harris, S.J.5
Harrison, G.P.6
Aboul-Ela, F.7
Varani, G.8
Walker, S.9
-
20
-
-
0033990403
-
Progress in antisense technology: The end of the beginning
-
Crooke ST (2000) Progress in antisense technology: the end of the beginning. Methods in Enzymology 313:3-45.
-
(2000)
Methods in Enzymology
, vol.313
, pp. 3-45
-
-
Crooke, S.T.1
-
21
-
-
0037044192
-
2′-O-methyl-RNA hairpins generate loop-loop complexes and selectively inhibit HIV-1 Tat-mediated transcription
-
Darfeuille F, Arzumanov A, Gait MJ, Di Primo C & Toulme JJ (2002a) 2′-O-methyl-RNA hairpins generate loop-loop complexes and selectively inhibit HIV-1 Tat-mediated transcription. Biochemistry 41:12186-12192.
-
(2002)
Biochemistry
, vol.41
, pp. 12186-12192
-
-
Darfeuille, F.1
Arzumanov, A.2
Gait, M.J.3
Di Primo, C.4
Toulme, J.J.5
-
22
-
-
0037162493
-
Loop-loop interaction of HIV-1 TAR RNA with N3′->P5′ deoxyphosphoramidate aptamers inhibits in vitro Tat-mediated transcription
-
Darfeuille F, Arzumanov A, Gryaznov S, Gait MJ, Di Primo C & Toulme JJ (2002b) Loop-loop interaction of HIV-1 TAR RNA with N3′->P5′ deoxyphosphoramidate aptamers inhibits in vitro Tat-mediated transcription. Proceedings of the National Academy of Sciences, USA 99:9709-9714.
-
(2002)
Proceedings of the National Academy of Sciences, USA
, vol.99
, pp. 9709-9714
-
-
Darfeuille, F.1
Arzumanov, A.2
Gryaznov, S.3
Gait, M.J.4
Di Primo, C.5
Toulme, J.J.6
-
23
-
-
0025039326
-
HIV-1 tat protein stimulates transcription by binding to a U-rich bulge in the stem of the TAR RNA structure
-
Dingwall C, Ernberg I, Gait MJ, Green SM, Heaphy S, Karn J, Lowe AD, Singh M & Skinner MA (1990) HIV-1 tat protein stimulates transcription by binding to a U-rich bulge in the stem of the TAR RNA structure. EMBO Journal 9:4145-4153.
-
(1990)
EMBO Journal
, vol.9
, pp. 4145-4153
-
-
Dingwall, C.1
Ernberg, I.2
Gait, M.J.3
Green, S.M.4
Heaphy, S.5
Karn, J.6
Lowe, A.D.7
Singh, M.8
Skinner, M.A.9
-
24
-
-
0037196599
-
Emergence and selection of RNA virus variants: Memory and extinction
-
Domingo E, Ruiz-Jarabo CM, Sierra S, Arias A, Pariente N, Baranowski E & Escarmis C (2002) Emergence and selection of RNA virus variants: memory and extinction. Virus Research 82:39-44.
-
(2002)
Virus Research
, vol.82
, pp. 39-44
-
-
Domingo, E.1
Ruiz-Jarabo, C.M.2
Sierra, S.3
Arias, A.4
Pariente, N.5
Baranowski, E.6
Escarmis, C.7
-
25
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
-
Druker BJ, Tamura S, Buchdunger E, Ohno S, Segal GM, Fanning S, Zimmermann J & Lydon NB (1996) Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nature Medicine 2:561-566.
-
(1996)
Nature Medicine
, vol.2
, pp. 561-566
-
-
Druker, B.J.1
Tamura, S.2
Buchdunger, E.3
Ohno, S.4
Segal, G.M.5
Fanning, S.6
Zimmermann, J.7
Lydon, N.B.8
-
26
-
-
0035986695
-
Structure of TAR RNA complexed with a Tat-TAR interaction nanomolar inhibitor that was identified by computational screening
-
Du Z, Lind KE & James TL (2002) Structure of TAR RNA complexed with a Tat-TAR interaction nanomolar inhibitor that was identified by computational screening. Chemistry & Biology 9:707-712.
-
(2002)
Chemistry & Biology
, vol.9
, pp. 707-712
-
-
Du, Z.1
Lind, K.E.2
James, T.L.3
-
27
-
-
0032546817
-
HIV-1 regulatory/accessory genes: Keys to unraveling viral and host cell biology
-
Emerman M & Malim MH (1998) HIV-1 regulatory/accessory genes: keys to unraveling viral and host cell biology. Science 280:1880-1884.
-
(1998)
Science
, vol.280
, pp. 1880-1884
-
-
Emerman, M.1
Malim, M.H.2
-
28
-
-
0033949057
-
Identification of ligands for RNA targets via structure-based virtual screening: HIV-1 TAR
-
Filikov AV, Mohan V, Vickers TA, Griffey RH, Cook PD, Abagyan RA & James T L (2000) Identification of ligands for RNA targets via structure-based virtual screening: HIV-1 TAR. Journal of Computer-Aided Molecular Design 14:593-610.
-
(2000)
Journal of Computer-Aided Molecular Design
, vol.14
, pp. 593-610
-
-
Filikov, A.V.1
Mohan, V.2
Vickers, T.A.3
Griffey, R.H.4
Cook, P.D.5
Abagyan, R.A.6
James, T.L.7
-
29
-
-
0036130616
-
Structure elucidation of the hepatitis B virus encapsidation signal by NMR on selectively labeled RNAs
-
Flodell S, Cromsigt J, Schleucher J, Kidd-Ljunggren K & Wijmenga S (2002) Structure elucidation of the hepatitis B virus encapsidation signal by NMR on selectively labeled RNAs. Journal of Biomolecular Structural & Dynamics 19:627-636.
-
(2002)
Journal of Biomolecular Structural & Dynamics
, vol.19
, pp. 627-636
-
-
Flodell, S.1
Cromsigt, J.2
Schleucher, J.3
Kidd-Ljunggren, K.4
Wijmenga, S.5
-
30
-
-
0030797950
-
Identification of a phosphodiester hexanucleotide that inhibits HIV-1 infection in vitro on covalent linkage of its 5′-end with a dimethoxytrityl residue
-
Furukawa H, Momota K, Agatsuma T, Yamamoto I, Kimura S & Shimada K (1997) Identification of a phosphodiester hexanucleotide that inhibits HIV-1 infection in vitro on covalent linkage of its 5′-end with a dimethoxytrityl residue. Antisense Nucleic Acid Drug Development 7:167-175.
-
(1997)
Antisense Nucleic Acid Drug Development
, vol.7
, pp. 167-175
-
-
Furukawa, H.1
Momota, K.2
Agatsuma, T.3
Yamamoto, I.4
Kimura, S.5
Shimada, K.6
-
31
-
-
0034783659
-
Targeting RNA with small-molecule drugs: Therapeutic promise and chemical challenges
-
Gallego J & Varani G (2001) Targeting RNA with small-molecule drugs: therapeutic promise and chemical challenges. Accounts of Chemical Research 34:836-843.
-
(2001)
Accounts of Chemical Research
, vol.34
, pp. 836-843
-
-
Gallego, J.1
Varani, G.2
-
32
-
-
0034766987
-
Biochemical and genetic studies of the initiation of human rhinovirus 2 RNA replication: Identification of a cis-replicating element in the coding sequence of 2A(pro)
-
Gerber K, Wimmer E & Paul AV (2001) Biochemical and genetic studies of the initiation of human rhinovirus 2 RNA replication: identification of a cis-replicating element in the coding sequence of 2A(pro). Journal of Virology 75:10979-10990.
-
(2001)
Journal of Virology
, vol.75
, pp. 10979-10990
-
-
Gerber, K.1
Wimmer, E.2
Paul, A.V.3
-
33
-
-
0037173613
-
Short interfering RNA confers intracellular antiviral immunity in human cells
-
Gitlin L, Karelsky S & Andino R (2002) Short interfering RNA confers intracellular antiviral immunity in human cells. Nature 418:430-434.
-
(2002)
Nature
, vol.418
, pp. 430-434
-
-
Gitlin, L.1
Karelsky, S.2
Andino, R.3
-
34
-
-
0027723181
-
Selection and design of high-affinity RNA ligands for HIV-1 Rev
-
Giver L, Bartel DP, Zapp ML, Green MR & Ellington AD (1993) Selection and design of high-affinity RNA ligands for HIV-1 Rev. Gene 137:19-24.
-
(1993)
Gene
, vol.137
, pp. 19-24
-
-
Giver, L.1
Bartel, D.P.2
Zapp, M.L.3
Green, M.R.4
Ellington, A.D.5
-
36
-
-
0030976612
-
An inhibitor of the Tat/TAR RNA interaction that effectively suppresses HIV-1 replication
-
Hamy F, Felder ER, Heizmann G, Lazdins J, Aboul-ela F, Varani G, Karn J & Klimkait T (1997) An inhibitor of the Tat/TAR RNA interaction that effectively suppresses HIV-1 replication. Proceedings of the National Academy of Sciences, USA 94:3548-3553.
-
(1997)
Proceedings of the National Academy of Sciences, USA
, vol.94
, pp. 3548-3553
-
-
Hamy, F.1
Felder, E.R.2
Heizmann, G.3
Lazdins, J.4
Aboul-ela, F.5
Varani, G.6
Karn, J.7
Klimkait, T.8
-
37
-
-
0029996016
-
Antisense oligonucleotide inhibition of hepatitis C virus gene expression in transformed hepatocytes
-
Hanecak R, Brown-Driver V, Fox MC, Azad RF, Furusako S, Nozaki C, Ford C, Sasmor H & Anderson KP (1996) Antisense oligonucleotide inhibition of hepatitis C virus gene expression in transformed hepatocytes. Journal of Virology 70:5203-5212.
-
(1996)
Journal of Virology
, vol.70
, pp. 5203-5212
-
-
Hanecak, R.1
Brown-Driver, V.2
Fox, M.C.3
Azad, R.F.4
Furusako, S.5
Nozaki, C.6
Ford, C.7
Sasmor, H.8
Anderson, K.P.9
-
39
-
-
0031933080
-
RNA as a drug target: Chemical, modelling, and evolutionary tools
-
Hermann T & Westhof E (1998) RNA as a drug target: chemical, modelling, and evolutionary tools. Current Opinion in Biotechnology 9:66-73.
-
(1998)
Current Opinion in Biotechnology
, vol.9
, pp. 66-73
-
-
Hermann, T.1
Westhof, E.2
-
40
-
-
0033535566
-
Docking of cationic antibiotics to negatively charged pockets in RNA folds
-
Hermann T & Westhof E (1999) Docking of cationic antibiotics to negatively charged pockets in RNA folds. Journal of Medicinal Chemistry 42:1250-1261.
-
(1999)
Journal of Medicinal Chemistry
, vol.42
, pp. 1250-1261
-
-
Hermann, T.1
Westhof, E.2
-
41
-
-
0033566617
-
Multiplexed screening of neutral mass-tagged RNA targets against ligand libraries with electrospray ionization FTICR MS: A paradigm for high-throughput affinity screening
-
Hofstadler SA, Sannes-Lowery KA, Crooke ST, Ecker DJ, Sasmor H, Manalili S & Griffey RH (1999) Multiplexed screening of neutral mass-tagged RNA targets against ligand libraries with electrospray ionization FTICR MS: a paradigm for high-throughput affinity screening. Analytical Chemistry 71:3436-3440.
-
(1999)
Analytical Chemistry
, vol.71
, pp. 3436-3440
-
-
Hofstadler, S.A.1
Sannes-Lowery, K.A.2
Crooke, S.T.3
Ecker, D.J.4
Sasmor, H.5
Manalili, S.6
Griffey, R.H.7
-
42
-
-
0032903304
-
A phylogenetically conserved stem-loop structure at the 5′ border of the internal ribosome entry site of hepatitis C virus is required for cap-independent viral translation
-
Honda M, Beard MR, Ping LH & Lemon SM (1999) A phylogenetically conserved stem-loop structure at the 5′ border of the internal ribosome entry site of hepatitis C virus is required for cap-independent viral translation. Journal of Virology 73:1165-1174.
-
(1999)
Journal of Virology
, vol.73
, pp. 1165-1174
-
-
Honda, M.1
Beard, M.R.2
Ping, L.H.3
Lemon, S.M.4
-
43
-
-
0032543957
-
A 1.3-A resolution crystal structure of the HIV-1 trans-activation response region RNA stem reveals a metal ion-dependent bulge conformation
-
Ippolito JA & Steitz TA (1998) A 1.3-A resolution crystal structure of the HIV-1 trans-activation response region RNA stem reveals a metal ion-dependent bulge conformation. Proceedings of the National Academy of Sciences, USA 95:9819-9824.
-
(1998)
Proceedings of the National Academy of Sciences, USA
, vol.95
, pp. 9819-9824
-
-
Ippolito, J.A.1
Steitz, T.A.2
-
44
-
-
0034723137
-
The structure of the HIV-1 RRE high affinity rev binding site at 1.6 A resolution
-
Ippolito JA & Steitz TA (2000) The structure of the HIV-1 RRE high affinity rev binding site at 1.6 A resolution. Journal of Molecular Biology 295:711-717.
-
(2000)
Journal of Molecular Biology
, vol.295
, pp. 711-717
-
-
Ippolito, J.A.1
Steitz, T.A.2
-
45
-
-
0037173610
-
Modulation of HIV-1 replication by RNA interference
-
Jacque JM, Triques K & Stevenson M (2002) Modulation of HIV-1 replication by RNA interference. Nature 418:435-438.
-
(2002)
Nature
, vol.418
, pp. 435-438
-
-
Jacque, J.M.1
Triques, K.2
Stevenson, M.3
-
46
-
-
0033765890
-
Hepatitis C virus internal ribosome entry site (IRES) stem loop IIId contains a phylogenetically conserved GGG triplet essential for translation and IRES folding
-
Jubin R, Vantuno NE, Kieft JS, Murray MG, Doudna JA, Lau JY & Baroudy BM (2000) Hepatitis C virus internal ribosome entry site (IRES) stem loop IIId contains a phylogenetically conserved GGG triplet essential for translation and IRES folding. Journal of Virology 74:10430-10437.
-
(2000)
Journal of Virology
, vol.74
, pp. 10430-10437
-
-
Jubin, R.1
Vantuno, N.E.2
Kieft, J.S.3
Murray, M.G.4
Doudna, J.A.5
Lau, J.Y.6
Baroudy, B.M.7
-
48
-
-
0036237981
-
Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiation
-
Kieft JS, Zhou K, Grech A, Jubin R & Doudna JA (2002) Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiation. Nature Structural Biology 9:370-374.
-
(2002)
Nature Structural Biology
, vol.9
, pp. 370-374
-
-
Kieft, J.S.1
Zhou, K.2
Grech, A.3
Jubin, R.4
Doudna, J.A.5
-
50
-
-
0033744387
-
A potential RNA drug target in the hepatitis C virus internal ribosomal entry site
-
Klinck R, Westhof E, Walker S, Afshar M, Collier A & Aboul-Ela F (2000) A potential RNA drug target in the hepatitis C virus internal ribosomal entry site. RNA 6:1423-1431.
-
(2000)
RNA
, vol.6
, pp. 1423-1431
-
-
Klinck, R.1
Westhof, E.2
Walker, S.3
Afshar, M.4
Collier, A.5
Aboul-Ela, F.6
-
51
-
-
0036061381
-
Targeted therapy of respiratory syncytial virus in African green monkeys by intranasally administered 2-5A antisense
-
Leaman DW, Longano FJ, Okicki JR, Soike KF, Torrence PF, Silverman RH & Cramer H (2002) Targeted therapy of respiratory syncytial virus in African green monkeys by intranasally administered 2-5A antisense. Virology 292:70-77.
-
(2002)
Virology
, vol.292
, pp. 70-77
-
-
Leaman, D.W.1
Longano, F.J.2
Okicki, J.R.3
Soike, K.F.4
Torrence, P.F.5
Silverman, R.H.6
Cramer, H.7
-
52
-
-
0031894779
-
Modeling RNA-ligand interactions: The Rev-binding element RNA-aminoglycoside complex
-
Leclerc F & Cedergren R (1998) Modeling RNA-ligand interactions: the Rev-binding element RNA-aminoglycoside complex. Journal of Medicinal Chemistry 41:175-182.
-
(1998)
Journal of Medicinal Chemistry
, vol.41
, pp. 175-182
-
-
Leclerc, F.1
Cedergren, R.2
-
53
-
-
0033848988
-
Pharmacokinetics and tissue distribution of a ribozyme directed against hepatitis C virus RNA following subcutaneous or intravenous administration in mice
-
Lee PA, Blatt LM, Blanchard KS, Bouhana KS, Pavco PA, Bellon L & Sandberg JA (2000) Pharmacokinetics and tissue distribution of a ribozyme directed against hepatitis C virus RNA following subcutaneous or intravenous administration in mice. Hepatology 32:640-646.
-
(2000)
Hepatology
, vol.32
, pp. 640-646
-
-
Lee, P.A.1
Blatt, L.M.2
Blanchard, K.S.3
Bouhana, K.S.4
Pavco, P.A.5
Bellon, L.6
Sandberg, J.A.7
-
54
-
-
0034494311
-
Non-specific antiviral activity of antisense molecules targeted to the E1 region of human papillomavirus
-
Lewis EJ, Agrawal S, Bishop J, Chadwick J, Cristensen ND, Cuthill S, Dunford P, Field AK, Francis J, Gibson V, Greenham AK, Kelly F, Kilkushie R, Kreider JW, Mills JS, Mulqueen M, Roberts NA, Roberts P & Szymkowski DE (2000) Non-specific antiviral activity of antisense molecules targeted to the E1 region of human papillomavirus. Antiviral Research 48:187-196.
-
(2000)
Antiviral Research
, vol.48
, pp. 187-196
-
-
Lewis, E.J.1
Agrawal, S.2
Bishop, J.3
Chadwick, J.4
Cristensen, N.D.5
Cuthill, S.6
Dunford, P.7
Field, A.K.8
Francis, J.9
Gibson, V.10
Greenham, A.K.11
Kelly, F.12
Kilkushie, R.13
Kreider, J.W.14
Mills, J.S.15
Mulqueen, M.16
Roberts, N.A.17
Roberts, P.18
Szymkowski, D.E.19
-
55
-
-
0031006594
-
Targeting the Tat-binding site of bovine immunodeficiency virus TAR RNA with a shape-selective rhodium complex
-
Lim AC & Barton JK (1997) Targeting the Tat-binding site of bovine immunodeficiency virus TAR RNA with a shape-selective rhodium complex. Bioorganic & Medicinal Chemistry 5:1131-1136.
-
(1997)
Bioorganic & Medicinal Chemistry
, vol.5
, pp. 1131-1136
-
-
Lim, A.C.1
Barton, J.K.2
-
56
-
-
0031032603
-
Combinatorial screening and rational optimization for hybridization to folded hepatitis C virus RNA of oligonucleotides with biological antisense activity
-
Lima WF, Brown-Driver V, Fox M, Hanecak R & Bruice TW (1997) Combinatorial screening and rational optimization for hybridization to folded hepatitis C virus RNA of oligonucleotides with biological antisense activity. Journal of Biological Chemistry 272:626-638.
-
(1997)
Journal of Biological Chemistry
, vol.272
, pp. 626-638
-
-
Lima, W.F.1
Brown-Driver, V.2
Fox, M.3
Hanecak, R.4
Bruice, T.W.5
-
57
-
-
0036008846
-
Structure-based computational database screening, in vitro assay, and NMR assessment of compounds that target TAR RNA
-
Lind KE, Du Z, Fujinaga K, Peterlin BM & James TL (2002) Structure-based computational database screening, in vitro assay, and NMR assessment of compounds that target TAR RNA. Chemistry & Biology 9:185-193.
-
(2002)
Chemistry & Biology
, vol.9
, pp. 185-193
-
-
Lind, K.E.1
Du, Z.2
Fujinaga, K.3
Peterlin, B.M.4
James, T.L.5
-
58
-
-
0035951091
-
Neomycin B-arginine conjugate, a novel HIV-1 Tat antagonist: Synthesis and anti-HIV activities
-
Litovchick A, Lapidot A, Eisenstein M, Kalinkovich A & Borkow G (2001) Neomycin B-arginine conjugate, a novel HIV-1 Tat antagonist: synthesis and anti-HIV activities. Biochemistry 40:15612-15625.
-
(2001)
Biochemistry
, vol.40
, pp. 15612-15625
-
-
Litovchick, A.1
Lapidot, A.2
Eisenstein, M.3
Kalinkovich, A.4
Borkow, G.5
-
59
-
-
0028058105
-
In vitro selection of RNA aptamers specific for cyanocobalamin
-
Lorsch JR & Szostak JW (1994) In vitro selection of RNA aptamers specific for cyanocobalamin. Biochemistry 33:973-982.
-
(1994)
Biochemistry
, vol.33
, pp. 973-982
-
-
Lorsch, J.R.1
Szostak, J.W.2
-
60
-
-
0035942172
-
Vitamin B12 and hepatitis C: Molecular biology and human pathology
-
Lott WB, Takyar SS, Tuppen J, Crawford DH, Harrison M, Sloots TP & Gowans EJ (2001) Vitamin B12 and hepatitis C: molecular biology and human pathology. Proceedings of the National Academy of Sciences, USA 98:4916-4921.
-
(2001)
Proceedings of the National Academy of Sciences, USA
, vol.98
, pp. 4916-4921
-
-
Lott, W.B.1
Takyar, S.S.2
Tuppen, J.3
Crawford, D.H.4
Harrison, M.5
Sloots, T.P.6
Gowans, E.J.7
-
61
-
-
0033673387
-
Structures of two RNA domains essential for hepatitis C virus internal ribosome entry site function
-
Lukavsky PJ, Otto GA, Lancaster AM, Sarnow P & Puglisi JD (2000) Structures of two RNA domains essential for hepatitis C virus internal ribosome entry site function. Nature Structural Biology 7:1105-1110.
-
(2000)
Nature Structural Biology
, vol.7
, pp. 1105-1110
-
-
Lukavsky, P.J.1
Otto, G.A.2
Lancaster, A.M.3
Sarnow, P.4
Puglisi, J.D.5
-
62
-
-
0035720187
-
RNAPack: An integrated NMR approach to RNA structure determination
-
Lukavsky PJ & Puglisi JD (2001) RNAPack: an integrated NMR approach to RNA structure determination. Methods 25:316-332.
-
(2001)
Methods
, vol.25
, pp. 316-332
-
-
Lukavsky, P.J.1
Puglisi, J.D.2
-
63
-
-
0035553604
-
Enhanced antiviral effect in cell culture of type 1 interferon and ribozymes targeting HCV RNA
-
Macejak DG, Jensen KL, Pavco PA, Phipps KM, Heinz BA, Colacino JM & Blatt LM (2001) Enhanced antiviral effect in cell culture of type 1 interferon and ribozymes targeting HCV RNA. Journal of Viral Hepatitis 8:400-405.
-
(2001)
Journal of Viral Hepatitis
, vol.8
, pp. 400-405
-
-
Macejak, D.G.1
Jensen, K.L.2
Pavco, P.A.3
Phipps, K.M.4
Heinz, B.A.5
Colacino, J.M.6
Blatt, L.M.7
-
64
-
-
0028108364
-
A molecular rheostat. Co-operative rev binding to stem I of the rev-response element modulates human immunodeficiency virus type-1 late gene expression
-
Mann DA, Mikaelian I, Zemmel RW, Green SM, Lowe AD, Kimura T, Singh M, Butler PJ, Gait MJ & Karn J (1994) A molecular rheostat. Co-operative rev binding to stem I of the rev-response element modulates human immunodeficiency virus type-1 late gene expression. Journal of Molecular Biology 241:193-207.
-
(1994)
Journal of Molecular Biology
, vol.241
, pp. 193-207
-
-
Mann, D.A.1
Mikaelian, I.2
Zemmel, R.W.3
Green, S.M.4
Lowe, A.D.5
Kimura, T.6
Singh, M.7
Butler, P.J.8
Gait, M.J.9
Karn, J.10
-
65
-
-
0032522198
-
In vitro selection of HIV-1 TAR variants by the Tat protein
-
Marozzi A, Meneveri R, Giacca M, Gutierrez MI, Siccardi AG & Ginelli E (1998) In vitro selection of HIV-1 TAR variants by the Tat protein. Journal of Biotechnology 61:117-128.
-
(1998)
Journal of Biotechnology
, vol.61
, pp. 117-128
-
-
Marozzi, A.1
Meneveri, R.2
Giacca, M.3
Gutierrez, M.I.4
Siccardi, A.G.5
Ginelli, E.6
-
66
-
-
0037032933
-
Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication
-
Martinez MA, Gutierrez A, Armand-Ugon M, Blanco J, Parera M, Gomez J, Clotet B & Este JA (2002) Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication. AIDS 16:2385-2390.
-
(2002)
AIDS
, vol.16
, pp. 2385-2390
-
-
Martinez, M.A.1
Gutierrez, A.2
Armand-Ugon, M.3
Blanco, J.4
Parera, M.5
Gomez, J.6
Clotet, B.7
Este, J.A.8
-
67
-
-
0031762554
-
The rhinovirus type 14 genome contains an internally located RNA structure that is required for viral replication
-
McKnight KL & Lemon SM (1998) The rhinovirus type 14 genome contains an internally located RNA structure that is required for viral replication. RNA 4:1569-1584.
-
(1998)
RNA
, vol.4
, pp. 1569-1584
-
-
McKnight, K.L.1
Lemon, S.M.2
-
68
-
-
0036639381
-
Footprinting, circular dichroism and UV melting studies on neomycin B binding to the packaging region of human immunodeficiency virus type-1 RNA
-
McPike MP, Sullivan JM, Goodisman J & Dabrowiak JC (2002) Footprinting, circular dichroism and UV melting studies on neomycin B binding to the packaging region of human immunodeficiency virus type-1 RNA. Nucleic Acids Research 30:2825-2831.
-
(2002)
Nucleic Acids Research
, vol.30
, pp. 2825-2831
-
-
McPike, M.P.1
Sullivan, J.M.2
Goodisman, J.3
Dabrowiak, J.C.4
-
69
-
-
0031005114
-
Discovery of selective, small-molecule inhibitors of RNA complexes-I. The Tat protein/TAR RNA complexes required for HIV-1 transcription
-
Mei HY, Mack DP, Galan AA, Halim NS, Heldsinger A, Loo JA, Moreland DW, Sannes-Lowery KA, Sharmeen L, Truong HN & Czarnik AW (1997) Discovery of selective, small-molecule inhibitors of RNA complexes-I. The Tat protein/TAR RNA complexes required for HIV-1 transcription. Bioorganic & Medicinal Chemistry 5:1173-1184.
-
(1997)
Bioorganic & Medicinal Chemistry
, vol.5
, pp. 1173-1184
-
-
Mei, H.Y.1
Mack, D.P.2
Galan, A.A.3
Halim, N.S.4
Heldsinger, A.5
Loo, J.A.6
Moreland, D.W.7
Sannes-Lowery, K.A.8
Sharmeen, L.9
Truong, H.N.10
Czarnik, A.W.11
-
70
-
-
0023614254
-
Regulation of mRNA accumulation by a human immunodeficiency virus trans-activator protein
-
Muesing MA, Smith DH & Capon DJ (1987) Regulation of mRNA accumulation by a human immunodeficiency virus trans-activator protein. Cell 48:691-701.
-
(1987)
Cell
, vol.48
, pp. 691-701
-
-
Muesing, M.A.1
Smith, D.H.2
Capon, D.J.3
-
71
-
-
0034671676
-
Molecular dynamics studies of the HIV-1 TAR and its complex with argininamide
-
Nifosi R, Reyes CM & Kollman PA (2000) Molecular dynamics studies of the HIV-1 TAR and its complex with argininamide. Nucleic Acids Research 28:4944-4955.
-
(2000)
Nucleic Acids Research
, vol.28
, pp. 4944-4955
-
-
Nifosi, R.1
Reyes, C.M.2
Kollman, P.A.3
-
72
-
-
0036066508
-
siRNA-directed inhibition of HIV-1 infection
-
Novina CD, Murray MF, Dykxhoorn DM, Beresford PJ, Riess J, Lee SK, Collman RG, Lieberman J, Shankar P & Sharp PA (2002) siRNA-directed inhibition of HIV-1 infection. Nature Medicine 8:681-686.
-
(2002)
Nature Medicine
, vol.8
, pp. 681-686
-
-
Novina, C.D.1
Murray, M.F.2
Dykxhoorn, D.M.3
Beresford, P.J.4
Riess, J.5
Lee, S.K.6
Collman, R.G.7
Lieberman, J.8
Shankar, P.9
Sharp, P.A.10
-
73
-
-
0036636074
-
Nucleic-acid therapeutics: Basic principles and recent applications
-
Opalinska JB & Gewirtz AM (2002) Nucleic-acid therapeutics: basic principles and recent applications. Nature Reviews Drug Discovery 1:503-514.
-
(2002)
Nature Reviews Drug Discovery
, vol.1
, pp. 503-514
-
-
Opalinska, J.B.1
Gewirtz, A.M.2
-
74
-
-
0034945407
-
Technology evaluation: Fomivirsen, Isis Pharmaceuticals Inc/CIBA vision
-
Orr RM (2001) Technology evaluation: fomivirsen, Isis Pharmaceuticals Inc/CIBA vision. Current Opinion in Molecular Therapy 3:288-294.
-
(2001)
Current Opinion in Molecular Therapy
, vol.3
, pp. 288-294
-
-
Orr, R.M.1
-
75
-
-
0029905917
-
Rapid combinatorial synthesis of aminoglycoside antibiotic mimetics: Use of a polyethylene glycol-linked amine and a neamine-derived aldehyde in multiple component condensation as a strategy for the discovery of new inhibitors of the HIV RNA rev responsive element
-
Park WKC, Auer M, Jaksche H & Wong C-H (1996) Rapid combinatorial synthesis of aminoglycoside antibiotic mimetics: use of a polyethylene glycol-linked amine and a neamine-derived aldehyde in multiple component condensation as a strategy for the discovery of new inhibitors of the HIV RNA rev responsive element. Journal of the American Chemical Society 118:10150-10155.
-
(1996)
Journal of the American Chemical Society
, vol.118
, pp. 10150-10155
-
-
Park, W.K.C.1
Auer, M.2
Jaksche, H.3
Wong, C.-H.4
-
76
-
-
0033766003
-
Identification of an RNA hairpin in poliovirus RNA that serves as the primary template in the in vitro uridylylation of VPg
-
Paul AV, Rieder E, Kim DW, van Boom JH & Wimmer E (2000) Identification of an RNA hairpin in poliovirus RNA that serves as the primary template in the in vitro uridylylation of VPg. Journal of Virology 74:10359-10370.
-
(2000)
Journal of Virology
, vol.74
, pp. 10359-10370
-
-
Paul, A.V.1
Rieder, E.2
Kim, D.W.3
Van Boom, J.H.4
Wimmer, E.5
-
77
-
-
0030596005
-
Structural change in Rev responsive element RNA of HIV-1 on binding Rev peptide
-
Peterson RD & Feigon J (1996) Structural change in Rev responsive element RNA of HIV-1 on binding Rev peptide. Journal of Molecular Biology 264:863-877.
-
(1996)
Journal of Molecular Biology
, vol.264
, pp. 863-877
-
-
Peterson, R.D.1
Feigon, J.2
-
79
-
-
0028185394
-
Common replication strategies emerging from the study of diverse groups of positive-strand RNA viruses
-
Pogue GP, Huntley CC & Hall TC (1994) Common replication strategies emerging from the study of diverse groups of positive-strand RNA viruses. Archives of Virology Supplement 9:181-194.
-
(1994)
Archives of Virology Supplement
, vol.9
, pp. 181-194
-
-
Pogue, G.P.1
Huntley, C.C.2
Hall, T.C.3
-
80
-
-
0037422607
-
Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs
-
Randall G, Grakoui A & Rice CM (2003) Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs. Proceedings of the National Academy of Sciences, USA 100:235-240.
-
(2003)
Proceedings of the National Academy of Sciences, USA
, vol.100
, pp. 235-240
-
-
Randall, G.1
Grakoui, A.2
Rice, C.M.3
-
81
-
-
0029961381
-
Inhibition of HIV-1 Rev-RRE interaction by diphenylfuran derivatives
-
Ratmeyer L, Zapp ML, Green MR, Vinayak R, Kumar A, Boykin DW & Wilson WD (1996) Inhibition of HIV-1 Rev-RRE interaction by diphenylfuran derivatives. Biochemistry 35:13689-13696.
-
(1996)
Biochemistry
, vol.35
, pp. 13689-13696
-
-
Ratmeyer, L.1
Zapp, M.L.2
Green, M.R.3
Vinayak, R.4
Kumar, A.5
Boykin, D.W.6
Wilson, W.D.7
-
82
-
-
0033992656
-
Internal ribosome entry site-mediated translation in hepatitis C virus replication
-
Rijnbrand RC & Lemon SM (2000) Internal ribosome entry site-mediated translation in hepatitis C virus replication. Current Topics in Microbiology & Immunology 242:85-116.
-
(2000)
Current Topics in Microbiology & Immunology
, vol.242
, pp. 85-116
-
-
Rijnbrand, R.C.1
Lemon, S.M.2
-
83
-
-
0343799864
-
Inhibition of the self-cleavage reaction of the human hepatitis delta virus ribozyme by antibiotics
-
Rogers J, Chang AH, von Ahsen U, Schroeder R & Davies J (1996) Inhibition of the self-cleavage reaction of the human hepatitis delta virus ribozyme by antibiotics. Journal of Molecuar Biology 259:916-925.
-
(1996)
Journal of Molecuar Biology
, vol.259
, pp. 916-925
-
-
Rogers, J.1
Chang, A.H.2
Von Ahsen, U.3
Schroeder, R.4
Davies, J.5
-
84
-
-
0034193686
-
Measuring dissociation constants of RNA and aminoglycoside antibiotics by electrospray ionization mass spectrometry
-
Sannes-Lowery KA, Griffey RH & Hofstadler SA (2000) Measuring dissociation constants of RNA and aminoglycoside antibiotics by electrospray ionization mass spectrometry. Analytical Biochemistry 280:264-271.
-
(2000)
Analytical Biochemistry
, vol.280
, pp. 264-271
-
-
Sannes-Lowery, K.A.1
Griffey, R.H.2
Hofstadler, S.A.3
-
85
-
-
0031573676
-
HIV-1 Tat peptide binding to TAR RNA by electrospray ionization mass spectrometry
-
Sannes-Lowery KA, Hu P, Mack DP, Mei HY & Loo JA (1997) HIV-1 Tat peptide binding to TAR RNA by electrospray ionization mass spectrometry. Analytical Chemistry 69:5130-5135.
-
(1997)
Analytical Chemistry
, vol.69
, pp. 5130-5135
-
-
Sannes-Lowery, K.A.1
Hu, P.2
Mack, D.P.3
Mei, H.Y.4
Loo, J.A.5
-
86
-
-
0037213594
-
Small Interfering RNA-mediated inhibition of hepatitis C virus replication in the human hepatoma cell line Huh-7
-
Seo MY, Abrignani S, Houghton M & Han JH (2003) Small Interfering RNA-mediated inhibition of hepatitis C virus replication in the human hepatoma cell line Huh-7. Journal of Virology 77:810-812.
-
(2003)
Journal of Virology
, vol.77
, pp. 810-812
-
-
Seo, M.Y.1
Abrignani, S.2
Houghton, M.3
Han, J.H.4
-
87
-
-
0035281741
-
RNA interference-2001
-
Sharp PA (2001) RNA interference-2001. Genes & Development 15:485-490.
-
(2001)
Genes & Development
, vol.15
, pp. 485-490
-
-
Sharp, P.A.1
-
88
-
-
0033991627
-
Selective RNA cleavage by isolated RNase L activated with 2-5A antisense chimeric oligonucleotides
-
Silverman RH, Dong B, Maitra RK, Player MR & Torrence PF (2000) Selective RNA cleavage by isolated RNase L activated with 2-5A antisense chimeric oligonucleotides. Methods in Enzymology 313:522-533.
-
(2000)
Methods in Enzymology
, vol.313
, pp. 522-533
-
-
Silverman, R.H.1
Dong, B.2
Maitra, R.K.3
Player, M.R.4
Torrence, P.F.5
-
89
-
-
0031017973
-
The origin of hepatitis C virus genotypes
-
Smith DB, Pathirana S, Davidson F, Lawlor E, Power J, Yap PL & Simmonds P (1997) The origin of hepatitis C virus genotypes. Journal of General Virology 78:321-328.
-
(1997)
Journal of General Virology
, vol.78
, pp. 321-328
-
-
Smith, D.B.1
Pathirana, S.2
Davidson, F.3
Lawlor, E.4
Power, J.5
Yap, P.L.6
Simmonds, P.7
-
90
-
-
0037194620
-
SAR by MS: A ligand based technique for drug lead discovery against structured RNA targets
-
Swayze EE, Jefferson EA, Sannes-Lowery KA, Blyn LB, Risen LM, Arakawa S, Osgood SA, Hofstadler SA & Griffey RH (2002) SAR by MS: a ligand based technique for drug lead discovery against structured RNA targets. Journal of Medicinal Chemistry 45:3816-3819.
-
(2002)
Journal of Medicinal Chemistry
, vol.45
, pp. 3816-3819
-
-
Swayze, E.E.1
Jefferson, E.A.2
Sannes-Lowery, K.A.3
Blyn, L.B.4
Risen, L.M.5
Arakawa, S.6
Osgood, S.A.7
Hofstadler, S.A.8
Griffey, R.H.9
-
91
-
-
0036306460
-
Vitamin B12 stalls the 80 s ribosomal complex on the hepatitis C internal ribosome entry site
-
Takyar SS, Gowans EJ & Lott WB (2002) Vitamin B12 stalls the 80 s ribosomal complex on the hepatitis C internal ribosome entry site. Journal of Molecular Biology 319:1-8.
-
(2002)
Journal of Molecular Biology
, vol.319
, pp. 1-8
-
-
Takyar, S.S.1
Gowans, E.J.2
Lott, W.B.3
-
93
-
-
0030844452
-
Selection of RNA aptamers that bind specifically to the NS3 protease of hepatitis C virus
-
Urvil PT, Kakiuchi N, Zhou DM, Shimotohno K, Kumar PK & Nishikawa S (1997) Selection of RNA aptamers that bind specifically to the NS3 protease of hepatitis C virus. European Journal of Biochemistry 248:130-138.
-
(1997)
European Journal of Biochemistry
, vol.248
, pp. 130-138
-
-
Urvil, P.T.1
Kakiuchi, N.2
Zhou, D.M.3
Shimotohno, K.4
Kumar, P.K.5
Nishikawa, S.6
-
95
-
-
0033692912
-
Nuclease-resistant synthetic ribozymes: Developing a new class of therapeutics
-
Usman N & Blatt LM (2000) Nuclease-resistant synthetic ribozymes: developing a new class of therapeutics. Journal of Clinical Investigation 106:1197-1202.
-
(2000)
Journal of Clinical Investigation
, vol.106
, pp. 1197-1202
-
-
Usman, N.1
Blatt, L.M.2
-
96
-
-
0032554635
-
Binding of neomycin to the TAR element of HIV-1 RNA induces dissociation of Tat protein by an allosteric mechanism
-
Wang S, Huber PW, Cui M, Czarnik AW & Mei HY (1998) Binding of neomycin to the TAR element of HIV-1 RNA induces dissociation of Tat protein by an allosteric mechanism. Biochemistry 37:5549-5557.
-
(1998)
Biochemistry
, vol.37
, pp. 5549-5557
-
-
Wang, S.1
Huber, P.W.2
Cui, M.3
Czarnik, A.W.4
Mei, H.Y.5
-
97
-
-
0342699722
-
Hepatitis C viral IRES inhibition by phenazine and phenazine-like molecules
-
Wang W, Preville P, Morin N, Mounir S, Cai W & Siddiqui MA (2000) Hepatitis C viral IRES inhibition by phenazine and phenazine-like molecules. Bioorganic & Medicinal Chemistry Letters 10:1151-1154.
-
(2000)
Bioorganic & Medicinal Chemistry Letters
, vol.10
, pp. 1151-1154
-
-
Wang, W.1
Preville, P.2
Morin, N.3
Mounir, S.4
Cai, W.5
Siddiqui, M.A.6
-
98
-
-
0031051477
-
Specificity of aminoglycoside binding to RNA constructs derived from the 16S rRNA decoding region and the HIV-RRE activator region
-
Wang Y, Hamasaki K & Rando RR (1997) Specificity of aminoglycoside binding to RNA constructs derived from the 16S rRNA decoding region and the HIV-RRE activator region. Biochemistry 36:768-779.
-
(1997)
Biochemistry
, vol.36
, pp. 768-779
-
-
Wang, Y.1
Hamasaki, K.2
Rando, R.R.3
-
100
-
-
10344260221
-
Design and analysis of RNA structure-specific agents as potential antivirals
-
Wilson WD, Ratmeyer L, Zhao M, Ding D, McConnaughie AW, Kumar A & Boykin DW (1996) Design and analysis of RNA structure-specific agents as potential antivirals. Journal of Molecular Recognition 9:187-196.
-
(1996)
Journal of Molecular Recognition
, vol.9
, pp. 187-196
-
-
Wilson, W.D.1
Ratmeyer, L.2
Zhao, M.3
Ding, D.4
McConnaughie, A.W.5
Kumar, A.6
Boykin, D.W.7
-
102
-
-
0032569212
-
A library approach to the discovery of small molecules that recognize RNA: Use of a 1,3-hydroxyamine motif as core
-
Wong C-H, Hendrix M, Manning DD, Rosenbohm C & Greenberg WA (1998) A library approach to the discovery of small molecules that recognize RNA: use of a 1,3-hydroxyamine motif as core. Journal of the American Chemical Society 120:8319-8327.
-
(1998)
Journal of the American Chemical Society
, vol.120
, pp. 8319-8327
-
-
Wong, C.-H.1
Hendrix, M.2
Manning, D.D.3
Rosenbohm, C.4
Greenberg, W.A.5
-
103
-
-
0035015697
-
Inhibition of the HIV-1 rev-RRE complex formation by unfused aromatic cations
-
Xiao G, Kumar A, Li K, Rigl CT, Bajic M, Davis TM, Boykin DW & Wilson WD (2001) Inhibition of the HIV-1 rev-RRE complex formation by unfused aromatic cations. Bioorganic & Medicinal Chemistry 9:1097-1113.
-
(2001)
Bioorganic & Medicinal Chemistry
, vol.9
, pp. 1097-1113
-
-
Xiao, G.1
Kumar, A.2
Li, K.3
Rigl, C.T.4
Bajic, M.5
Davis, T.M.6
Boykin, D.W.7
Wilson, W.D.8
-
104
-
-
0036314310
-
Sequence requirements for viral RNA replication and VPg uridylylation directed by the internal cis-acting replication element (cre) of human rhinovirus type 14
-
Yang Y, Rijnbrand R, McKnight KL, Wimmer E, Paul A, Martin A & Lemon SM (2002) Sequence requirements for viral RNA replication and VPg uridylylation directed by the internal cis-acting replication element (cre) of human rhinovirus type 14. Journal of Virology 76:7485-7494.
-
(2002)
Journal of Virology
, vol.76
, pp. 7485-7494
-
-
Yang, Y.1
Rijnbrand, R.2
McKnight, K.L.3
Wimmer, E.4
Paul, A.5
Martin, A.6
Lemon, S.M.7
-
105
-
-
0026493730
-
A molecular mechanics investigation of RNA complexes. I. Ethidium intercalation in an HIV-1 TAR RNA sequence with an unpaired adenosine
-
Yao S & Wilson WD (1992) A molecular mechanics investigation of RNA complexes. I. Ethidium intercalation in an HIV-1 TAR RNA sequence with an unpaired adenosine. Journal of Biomolecular Structural Dynamics 10:367-387.
-
(1992)
Journal of Biomolecular Structural Dynamics
, vol.10
, pp. 367-387
-
-
Yao, S.1
Wilson, W.D.2
-
106
-
-
0032730633
-
Phase I study of an antisense oligonucleotide to protein kinase C-α (ISIS 3521/CGP 64128A) in patients with cancer
-
Yuen AR, Halsey J, Fisher GA, Holmlund JT, Geary RS, Kwoh TJ, Dorr A & Sikic BI (1999) Phase I study of an antisense oligonucleotide to protein kinase C-α (ISIS 3521/CGP 64128A) in patients with cancer. Clinical Cancer Research 5:3357-3363.
-
(1999)
Clinical Cancer Research
, vol.5
, pp. 3357-3363
-
-
Yuen, A.R.1
Halsey, J.2
Fisher, G.A.3
Holmlund, J.T.4
Geary, R.S.5
Kwoh, T.J.6
Dorr, A.7
Sikic, B.I.8
-
107
-
-
0031005113
-
Modulation of the Rev-RRE interaction by aromatic heterocyclic compounds
-
Zapp ML, Young DW, Kumar A, Singh R, Boykin DW, Wilson WD & Green MR (1997) Modulation of the Rev-RRE interaction by aromatic heterocyclic compounds. Bioorganic & Medicinal Chemistry 5:1149-1155.
-
(1997)
Bioorganic & Medicinal Chemistry
, vol.5
, pp. 1149-1155
-
-
Zapp, M.L.1
Young, D.W.2
Kumar, A.3
Singh, R.4
Boykin, D.W.5
Wilson, W.D.6
Green, M.R.7
-
108
-
-
0034615776
-
The major HIV-1 packaging signal is an extended bulged stem loop whose structure is altered on interaction with the Gag polyprotein
-
Zeffman A, Hassard S, Varani G & Lever A (2000) The major HIV-1 packaging signal is an extended bulged stem loop whose structure is altered on interaction with the Gag polyprotein. Journal of Molecular Biology 297:877-893.
-
(2000)
Journal of Molecular Biology
, vol.297
, pp. 877-893
-
-
Zeffman, A.1
Hassard, S.2
Varani, G.3
Lever, A.4
-
109
-
-
0032995650
-
Antisense oligonucleotide inhibition of hepatitis C virus (HCV) gene expression in livers of mice infected with an HCV-vaccinia virus recombinant
-
Zhang H, Hanecak R, Brown-Driver V, Azad R, Conklin B, Fox MC & Anderson KP (1999) Antisense oligonucleotide inhibition of hepatitis C virus (HCV) gene expression in livers of mice infected with an HCV-vaccinia virus recombinant. Antimicrobial Agents & Chemotherapy 43:347-353.
-
(1999)
Antimicrobial Agents & Chemotherapy
, vol.43
, pp. 347-353
-
-
Zhang, H.1
Hanecak, R.2
Brown-Driver, V.3
Azad, R.4
Conklin, B.5
Fox, M.C.6
Anderson, K.P.7
-
110
-
-
0035081519
-
Genetic analysis of a poliovirus/hepatitis C virus chimera: New structure for domain II of the internal ribosomal entry site of hepatitis C virus
-
Zhao WD & Wimmer E (2001) Genetic analysis of a poliovirus/hepatitis C virus chimera: new structure for domain II of the internal ribosomal entry site of hepatitis C virus. Journal of Virology 75:3719-3730.
-
(2001)
Journal of Virology
, vol.75
, pp. 3719-3730
-
-
Zhao, W.D.1
Wimmer, E.2
-
111
-
-
0032850206
-
Technology evaluation: GEM-92, Hybridon Inc
-
Zheng R (1999) Technology evaluation: GEM-92, Hybridon Inc. Current Opinion in Molecular Therapy 1:521-523.
-
(1999)
Current Opinion in Molecular Therapy
, vol.1
, pp. 521-523
-
-
Zheng, R.1
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