A potential RNA drug target in the hepatitis C virus internal ribosomal entry site

RNA

Volumn 6, Issue 10, 2000, Pages 1423-1431

  Klinck, Roscoe ^a   Westhof, Eric ^b   Walker, Stephen ^a   Afshar, Mohammad ^a   Collier, Adam ^a   Aboul Ela, Fareed ^a  

^a RiboTargets Ltd   (United Kingdom)

^b CNRS   (France)

Author keywords

5' UTR; Bioinformatics; Drug design; G U pair; HCV IRES; NMR; RNA motif; S motif; Sarcin ricin loop (SRL)

Indexed keywords

ALPHA SARCIN; CELL PROTEIN; RICIN; RNA; TRINUCLEOTIDE;

ARTICLE; BASE PAIRING; DRUG DESIGN; DRUG TARGETING; HEPATITIS C VIRUS; MOLECULAR MODEL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; RIBOSOME; RNA TRANSLATION;

BASE PAIRING; BASE SEQUENCE; COMPUTATIONAL BIOLOGY; DRUG DESIGN; ENDORIBONUCLEASES; FUNGAL PROTEINS; GENETIC ENGINEERING; HEPACIVIRUS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEIC ACID CONFORMATION; PROTEIN BIOSYNTHESIS; REGULATORY SEQUENCES, NUCLEIC ACID; REPRODUCIBILITY OF RESULTS; RIBOSOMES; RICIN; RNA, MESSENGER; RNA, VIRAL; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

ANIMALIA; DNA VIRUSES; HEPATITIS C VIRUS;

EID: 0033744387     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838200000935     Document Type: Article

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