Measuring dissociation constants of RNA and aminoglycoside antibiotics by electrospray ionization mass spectrometry

Analytical Biochemistry

Volumn 280, Issue 2, 2000, Pages 264-271

  Sannes Lowery, Kristin A ^a   Griffey, Richard H ^a   Hofstadler, Steven A ^a  

^a ISIS PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; BINDING SITES; DISSOCIATION; ELECTRODEPOSITION; LIGANDS; MASS SPECTROMETRY; RNA;

AMINOGLYCOSIDE ANTIBIOTICS; DISSOCIATION CONSTANT; ELECTROSPRAY IONIZATION MASS SPECTROMETRY; LIGAND CONCENTRATION; NON-SPECIFIC BINDING; SALT CONCENTRATION; SOLUTION CONDITIONS; TARGET CONCENTRATIONS;

ELECTROSPRAY IONIZATION;

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ORGANIC SOLVENT; PAROMOMYCIN; RNA; RNA 16S; SODIUM CHLORIDE; TOBRAMYCIN;

ARTICLE; DISSOCIATION CONSTANT; DRUG BINDING SITE; DRUG DETERMINATION; ELECTRICITY; MASS SPECTROMETRY; PRIORITY JOURNAL; RNA ANALYSIS; STOICHIOMETRY;

EID: 0034193686     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1006/abio.2000.4550     Document Type: Article

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