Structure of TAR RNA complexed with a Tat-TAR interaction nanomolar inhibitor that was identified by computational screening

Chemistry and Biology

Volumn 9, Issue 6, 2002, Pages 707-712

  Du, Zhihua ^a   Lind, Kenneth E ^a   James, Thomas L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACEPROMAZINE; ANTI-HIV AGENTS; BINDING SITES; DRUG DESIGN; GENE PRODUCTS, TAT; HIV LONG TERMINAL REPEAT; HIV-1; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; NANOTECHNOLOGY; NUCLEIC ACID CONFORMATION; RNA, VIRAL; RNA-BINDING PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, U.S. GOV'T, P.H.S.; TRANS-ACTIVATION (GENETICS); VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

ACEPROMAZINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; RNA BINDING PROTEIN; TRANSACTIVATOR PROTEIN; VIRUS RNA;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG ANTAGONISM; DRUG DESIGN; DRUG EFFECT; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS 1; LONG TERMINAL REPEAT; METABOLISM; NANOTECHNOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE ACTIVITY RELATION; TRANSACTIVATION; VIRUS REPLICATION;

EID: 0035986695     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(02)00151-5     Document Type: Article

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