2′-O-methyl-RNA hairpins generate loop-loop complexes and selectively inhibit HIV-1 tat-mediated transcription

Biochemistry

Volumn 41, Issue 40, 2002, Pages 12186-12192

  Darfeuille, Fabien ^a,b   Arzumanov, Andrey ^c   Gait, Michael J ^c   Di Primo, Carmelo ^a,b   Toulmé, Jean Jacques ^a,b  

^a INSERM   (France)

^b INSTITUT EUROPÉEN DE CHIMIE ET BIOLOGIE   (France)

^c MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; SURFACE PLASMON RESONANCE; ULTRAVIOLET RADIATION; VIRUSES;

HAIRPIN APTAMERS;

RNA;

2' O METHYL RNA; APTAMER; CELL EXTRACT; NUCLEIC ACID; OLIGONUCLEOTIDE; RNA DERIVATIVE; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG; VIRUS RNA; RNA;

ARTICLE; CELL FREE SYSTEM; DENATURATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LIFESPAN; MOLECULAR INTERACTION; PRIORITY JOURNAL; RNA BINDING; RNA STRUCTURE; SURFACE PLASMON RESONANCE; ULTRAVIOLET RADIATION; CONFORMATION; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; GENETICS; HELA CELL; KINETICS; LONG TERMINAL REPEAT; METABOLISM; TEMPERATURE;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

GENE EXPRESSION REGULATION, VIRAL; GENE PRODUCTS, TAT; HELA CELLS; HIV LONG TERMINAL REPEAT; HIV-1; HUMANS; KINETICS; NUCLEIC ACID CONFORMATION; RNA; RNA, VIRAL; TEMPERATURE; TRANSCRIPTION, GENETIC;

EID: 0037044192     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi025974d     Document Type: Article

References (40)

1. Sczakiel, G. (2000) Front. Biosci. 5, D194-D201.
2. Sohail, M., Akhtar, S., and Southern, E. M. (1999) RNA 5, 646-655.
3. Smith, L., Andersen, K. B., Hovgaard, L., and Jaroszewski, J. W. (2000) Eur. J. Pharm. Sci. 11, 191-198.
4. Lehmann, M. J., Patzel, V., and Sczakiel, G. (2000) Nucleic Acids Res. 28, 2597-2604.
5. Monia, B. P., Johnston, J. F., Sasmor, H., and Cummins, L. L. (1996) J. Biol. Chem. 271, 14533-14540.
6. Chen, T. Z., Lin, S. B., Wu, J. C., Choo, K. B., and Au, L. C. (1996) J. Biochem. 119, 252-255.
7. Peyman, A., Helsberg, M., Kretzschmar, G., Mag, M., Grabley, S., and Uhlmann, E. (1995) Biol. Chem. Hoppe-Seyler376, 195-198.
8. Matveeva, O., Felden, B., Audlin, S., Gesteland, R. F., and Atkins, J. F. (1997) Nucleic Acids Res. 25, 5010-5016.
9. Allawi, H. T., Dong, F., Ip, H. S., Neri, B. P., and Lyamichev, V. I. (2001) RNA 7, 314-327.
10. Sohail, M., and Southern, E. M. (2001) Methods Mol. Biol. 170, 181-199.
11. Mir, K. U., and Southern, E. M. (1999) Nat. Biotechnol. 17, 788-792.
12. Amarzguioui, M., Brede, G., Babaie, E., Grotli, M., Sproat, B., and Prydz, H. (2000) Nucleic Acids Res. 28, 4113-4124.
13. Toulmé, J. J., Di Primo, C., and Moreau, S. (2001) Prog. Nucleic Acid Res. Mol. Biol. 69, 1-46.
14. Aldaz-Carroll, L., Tallet, B., Dausse, E., Yurchenko, L., and Toulmé, J. J. (2002) Biochemistry 41, 5883-5893.
15. Ducongé, F., and Toulmé, J. J. (1999) RNA 5, 1605-1614.
16. Ducongé, F., Di Primo, C., and Toulmé, J. J. (2000) J. Biol. Chem. 275, 21287-21294.
17. Osborne, S. E., Matsumura, I., and Ellington, A. D. (1997) Curr. Opin. Chem. Biol. 1, 5-9.
18. Kusser, W. (2000) J. Biotechnol. 74, 27-38.
19. Arzumanov, A., Walsh, A. P., Liu, X., Rajwanshi, V. K., Wengel, J., and Gait, M. J. (2001) Nucleosides, Nucleotides Nucleic Acids 20, 471-480.
20. Arzumanov, A., Walsh, A. P., Rajwanshi, V. K., Kumar, R., Wengel, J., and Gait, M. J. (2001) Biochemistry 40, 14645-14654.
21. Keen, N. J., Gait, M. J., and Karn, J. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 2505-2510.
22. Selby, M. J., Bain, E. S., Luciw, P. A., and Peterlin, B. M. (1989) Genes Dev. 3, 547-558.
23. Darfeuille, F., Cazenave, C., Gryaznov, S, Duconge, F., Di Primo, C., and Toulmé, J. J. (2001) Nucleosides, Nucleotides Nucleic Acids 20, 441-449.
24. Egli, M. (1996) Angew. Chem., Int. Ed. 35, 1894-1909.
25. Lukavsky, P. J., Otto, G. A., Lancaster, A. M., Sarnow, P., and Puglisi, J. D. (2000) Nat. Struct. Biol. 7, 1105-1110.
26. Klinck, R., Westhof, E., Walker, S., Afshar, M., Collier, A., and Aboul Ela, F. (2000) RNA 6, 1423-1431.
27. Lodmell, J. S., Ehresmann, C., Ehresmann, B., and Marquet, R. (2000) RNA 6, 1267-1276.
28. Jossinet, F., Paillart, J. C., Westhof, E., Hermann, T., Skripkin, E., Lodmell, J. S., Ehresmann, C., Ehresmann, B., and Marquet, R. (1999) RNA 5, 1222-1234.
29. Lodmell, J. S., Ehresmann, C., Ehresmann, B., and Marquet, R. (2001) J. Mol. Biol. 311, 475-490.
30. Stocks, M. R., and Rabbitts, T. H. (2000) EMBO Rep. 1, 59-64.
31. Svinarchuk, F., Cherny, D., Debin, A., Delain, E., and Malvy, C. (1996) Nucleic Acids Res. 24, 3858-3865.
32. Testa, S. M., Gryaznov, S. M., and Turner, D. H. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 2734-2739.
33. Tomizawa, J. I. (1984) Cell 38, 861-870.
34. Kolb, F. A., Malmgren, C., Westhof, E., Ehresmann, C., Ehresmann, B., Wagner, E. G., and Romby, P. (2000) RNA 6, 311- 324.
35. Argaman, L., and Altuvia, S. (2000) J. Mol. Biol. 300, 1101- 1112.
36. Paillart, J. C.- Skripkin, E., Ehresmann, B., Ehresmann, C., and Marquet, R. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 5572-5577.
37. Kim, C. H., and Tinoco, I., Jr. (2000) Proc. Natl. Acad. Sci. U.S.A. 97, 9396-9401.
38. Berkhout, B., Vastenhouw, N. L., Klasens, B. I., and Huthoff, H. (2001) RNA 7, 1097-1114.
39. Ferrandon, D., Koch, I., Westhof, E., and Nusslein-Volhard, C. (1997) EMBO J. 16, 1751-1758.
40. Andersen, A. A., and Collins, R. A. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 7730-7735.