Binding of neomycin to the TAR element of HIV-1 RNA induces dissociation of Tat protein by an allosteric mechanism

Biochemistry

Volumn 37, Issue 16, 1998, Pages 5549-5557

  Wang, Shaohui ^a   Huber, Paul W ^a   Cui, Mei ^b   Czarnik, Anthony W ^b   Mei, Houng Yau ^a,b  

^a UNIVERSITY OF NOTRE DAME   (United States)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE; INOSINE; NEOMYCIN; TRANSACTIVATOR PROTEIN; VIRUS RNA;

ALLOSTERISM; ARTICLE; BINDING SITE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSOCIATION; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROTEIN RNA BINDING; RNA STRUCTURE; TRANSACTIVATION;

ALLOSTERIC REGULATION; BINDING SITES; GENE PRODUCTS, TAT; GUANOSINE; HIV LONG TERMINAL REPEAT; HIV-1; INOSINE; MUTAGENESIS; NEOMYCIN; NUCLEIC ACID CONFORMATION; RNA, VIRAL;

EID: 0032554635     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi972808a     Document Type: Article

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